<> 86148161.indd 1 you. This isbecauseCanesten ThrushCombi maynotbethe righttreatment for • • • • • • Cream, youshouldseeyourdoctorif: Before usingCanesten® ThrushCombi SoftGelPessary andExternal • • Cream: Do notuseCanesten®ThrushCombi SoftGelPessary andExternal 2. antifungal agentwhichfightsthecauseofinfectionssuchasvaginal thrush. Clotrimazole belongstoagroup ofmedicinescalledazolesandisan The activesubstanceinCanestenThrushCombi isclotrimazole. doctor ashavingvaginal thrush. Only usethisproduct if youhavebeenpreviously diagnosedbyyour cause andexternalsymptoms. complete treatment forvaginal thrushbecauseittreats boththeinternal Canesten ThrushCombi Soft Gel Pessary andExternal Cream isa 1. 6. 5 4. 3. 2. 1. IN THISLEAFLET • • • • the bestresults from it. Canesten ThrushCombi SoftGelPessary andExternal Cream carefully toget This medicineisavailable withoutprescription. However, youstillneedtouse information foryou. Read allofthisleafletcarefully becauseitcontainsimportant

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• • • • • • • • • You haveanyofthefollowingsymptoms: antifungal products. You haveeverhadanaller You ar You oryourpartnerhaveeverhadasexuallytr You havehadmor had thesesymptoms. You ar To tr Further Information). Combi Soft Gel Pessary andExternal 6. Cream (seeSection ingredients, alcohol,ofCanestenThrush includingcetostearyl If youar Further information How tostor Possible sideeffects How touseCanestenThrushC Before youuseCanestenThrushC What isCanestenThrushCombi andwhatisitusedfor? pharmacist. If youhaveanyunusualeffectsafterusingthispr 7 You mustcontactadoctorifyoursymptomsworsenordonotimpr Ask yourpharmacistifyouneedmore informationoradvice Keep thisleaflet.Y

AND WHA WHAT ISCANESTEN®THRUSHCOMBI C BEFORE YOU USECANESTEN®THRUSH days. D A foulsmellingdischarge fr Feeling sickorvomiting. Fever orchills Pain or difficult Lower abdominalpain. Ulcers Abnormal vaginal bleedingorablood-staineddischar Irr OMBI eat nailandscalpinfections. iarrhoea. egular vaginal bleeding. e agedunder16orover60. e unsure whetheryouhavethrushorthisisthefirsttime e allergic (hypersensitive) toclotrimazoleoranyoftheother , blistersorsores ofthevagina orvulva. e CanestenThrushCombi Ca . y inpassingurine. e than two infectionsofthrushinthelastsixmonths.e thantwo ou mayneedtoread itagain. T ISITUSEDFOR? gic reaction toCanestenoranyothervaginal om thevagina. nesten ombi ombi ansmitted disease. oduct, tell your doctor or oduct, tellyourdoctoror ge. . ove in 2. 1. afterwards whenyouhave usedtheapplicator. Wash yourhandsbefore removing thefoilfrom theblisterpackandagain comfortable treatment. the vagina, preferably before goingtosleepatnightforconvenientand ashighpossibleinto The applicatorshouldbeusedtoinsertthepessary The SoftGelPessary: product without a prescription, followthesedirections closely. follow anyinstructionshe/she may havegivenyou.If youpurchased this If CanestenThrush Combi hasbeenprescribed foryoubyyourdoctor, 3. The cream alcoholwhichmaycauselocalskinirritation containscetostearyl Important informationaboutsome oftheingredients: pessary withoutthehelpofanapplicator.pessary To treat internalthrush,yourdoctormayrecommend that youusethe doctor ormidwifealready, instructionscarefully. followhis/her midwife before usingCanesten ThrushCombi. If youhaveinformedyour If youare pregnant, breast-feeding forababy, ortrying tellyourdoctoror Pregnancy andbreast-feeding: the immuneresponse toprevent rejection afteranorgan transplant). Inform yourdoctorifyouare takingtacrolimus orsirolimus (usedtoreduce any othermedicines, includingmedicines obtainedwithoutaprescription. Please tellyourdoctororpharmacistifyouare takingorhaverecently taken Using othermedicines: Do notusethisproduct duringyourperiodasitmaybelesseffective. product becauseyourpartnercouldbecomeinfected. Avoid vaginal intercourse whileyouhavethrushandduringuseofthis products whileusingthisproduct. Do notusetampons, intravaginal douches, spermicidesorothervaginal after usingthisproduct. Consequently, youshouldusealternativeprecautions foratleastfivedays effectiveness ofrubbercontraceptives, suchascondomsordiaphragms. As withothercreams andpessaries, thisproduct mayreduce the Special precautions: (e.

g. rash, itchingorredness).

Cream External & Pessary Gel Combi Soft Thrush Clotrimazole 500mg vaginalcapsule&2%w/wcream C HOW TO USECANESTEN®THRUSH applicator B, fitstightlyintotheapplicator. Thepessary byalighttwist. Fix theSoftGelPessar into theapplicatorB. it stops. Remove from thepessary thefoilblisterpackandplacefirmly Remove theapplicatorfr OMBI y firmlyintothedesignatedholderof om thepackaging.Pull out theplungerAuntil 05.12.17 10:59

Black

Pantone 485 U

Pantone Cool CAN Soft Gel Pessary Combi GB Gray 11 U

210 x 297 mm

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Verlag Book, Book Italic, Bold, Bold Italic; Zapf Dingbats Regular; Bliss Pro Medium 9 pt <> 86148161.indd 2 or contacttheAccidentandEmergency Department ofyournearest hospital. If orcream thepessary are swallowed accidentally, tellyourdoctorstraight away Do orcream notputthepessary inyourmouthorswallow them. The cream isfor externaluseonly: The SoftGelPessary isforuseinthevagina only. more infectionswithinsixmonthsyoushouldseeyourdoctor. thantwo returns aftersevendaysyoumayuseonefurthertreatment, but ifyouhave improvement isseenaftersevendaysyoumusttellyourdoctor. If theinfection The symptomsofthrushshoulddisappearwithinthree daysoftreatment. If no the symptomsofinfectiondisappear. 3 timesadayandsmoothedingently. Treatment shouldbecontinueduntil thinly andevenlyappliedtothearea around theentrance ofthevagina, 2or To treat theitchingandsoreness ofthevulva (vulvitis),thecream shouldbe tube andpress. Before use, pierce thetubesealbyinvertingcapoverendof The Cream: liner. dissolvesinthevagina, Since thepessary itmaybehelpfultowearapanty 4. 3. protect from moisture. This product shouldbestored placein order intheoriginalcartonadry to Do notstore above30°C. Keep thismedicine outofthesightandreach ofchildren. 5. ofthismedicine.safety By reporting sideeffectsyoucanhelpprovide more informationonthe www.mhra.gov.uk/yellowcard also report sideeffectsdirectly viatheYellow Card Schemeat: This includes anypossiblesideeffectsnotlistedinthisleaflet.You can If yougetanysideeffects, talktoyourdoctor, pharmacistornurse. Reporting ofsideeffects immediately. If youexperienceanyoftheaboveeffects, tellyourdoctororpharmacist • After youapply the cream youmightexperience: • • After youmightexperience: youusethe pessary • • • • hospital. Signsofanallergic reaction mayinclude: or contacttheAccidentandEmergency Department ofyournearest swelling getworse, stopusingthisproduct andtellyourdoctorstraight away you experienceanallergic reaction ortheredness, burning,pain,itchingor are allergic, areaction willoccursoonafteryouhaveusedthemedicine. If all medicines, somepeoplemaybeallergic orcream. tothepessary If you Cream cancause sideeffects, getsthem.Aswith althoughnoteverybody Like allmedicines, CanestenThrushCombi SoftGelPessary andExternal 4. •

peeling ofskin. Itching, r Pain intheabdomenorpelvicar peeling orbleeding. Itching, r N Weakness Swelling ofyourlips, f Swallowing orbr Rash.

C HOW TO STORE CANESTEN®THRUSH the r Remove theapplicator. Dispose oftheapplicatorinasafeplace, outof isdepositedintothevagina.that thepessary H (this iseasiestwhenlyingonyourbackwithkneesbentup). Carefully puttheapplicatorasdeepiscomfortableintovagina POSSIBLE SIDEEFFECTS ausea. olding theapplicatorinplace, slowlypress theplungeruntilitstopsso OMBI each ofchildren. Theapplicatorcannotbeflusheddownthetoilet. ash, blisters, burning,discomfort,swelling,redness, irritationor ash, swelling,redness, discomfort,burning,irritation,vaginal , feelingdizzyorfaint. eathing problems. ace, throat ortongue. ea. Canesten isaregistered trademark ofBayerAG, Germany. This leafletwas lastrevised inOctober 2017. Calls charged atlocalrate. information, callourCanestenAdvice Lineon0845758 5030. For UKresidents only: ifyouhaveanyquestionsorwouldlike more advice. treatment ofthrush,donothesitatetoaskyourdoctororpharmacistfor If youare stillworriedorhaveanyquestionsaboutthesymptoms 7 7 7 3 3 3 3 How toavoidfuture recurrences: these symptoms;youmayhaveonlyoneofthem. odourless discharge from thevagina. Not whohasthrush all everybody swelling andsoreness of thetissuesofvagina andvulva andawhitish, persistent burningand/oritchingaround thevagina andvulva, redness, develop intoathrushinfectioncausinganyofthefollowingsymptoms: If thenatural pHbalanceisaltered, thelevelofyeastincreases andcan perfumed soaps, bathadditivesandtightclothing. contraceptive pill, pregnancy, menopause),poorhealth,antibiotics, upset bymanyfactors such ashormonalchanges(menstruation, However, thenatural balancethatkeeps Candidaundercontrol canbe in thevagina andother parts ofthebody, without youevennoticingit. Thrush iscausedbyayeast(fungus)calledCandidawhichlivesharmlessly hygiene. from atsometime intheirlivesandisnotcausedbylackofpersonal Vaginal thrush(candidiasis) isacommoninfectionthatmostwomensuffer Further informationaboutvaginal thrush: orpharmacist. doctor Soft GelPessary andExternal Cream correctly, seektheadviceof your Remember: If youhave anydoubtsaboutusingCanesten® ThrushCombi 79639 Grenzach-Wyhlen, Germany. GP Grenzach Produktions GmbH, Manufacturer: 400SouthOakBayer plc, Way, Reading, RG2 6AD, UK. Marketing AuthorisationHolder: intothevaginaof thepessary andone10gtubeofwhiteexternalcream. soft vaginal capsuleheldinsideafoilblister pack, oneapplicator for insertion full courseoftreatment, whichconsistsofasingleyellowteardropshaped Canesten ThrushCombi SoftGelPessary andExternal Cream containsa looks like andcontentsofthepack: What Canesten®ThrushCombi SoftGelPessary andExternal Cream • • Cream: • • Soft GelPessary: What Canesten®ThrushCombi SoftGelPessary andCream contains: 6. measures willhelptoprotect theenvironment. Ask yourpharmacisthowtodisposeofmedicinesnolongerrequired. These Medicines shouldnotbedisposedofviawastewater or householdwaste. the tubeofcream. daterefers Theexpiry tothelastdayofthatmonth. andontheendof end ofthecarton,onfoilblisterstrippessary Do orcream datewhichisstatedatone notusethepessary aftertheexpiry

baths withstrong perfumedoils. infection maybetransferred from thebowel. ingredients’ forcetostearyl alcoholadvice. 2‘D See Section purified water. stearate, palmitate, and cetyl alcohol,octyldodecanol cetostearyl The otheringredients ar The activesubstanceisclotrimazoleatastrength of2%w yellow (E110),lecithin,medium-chaintriglycerides. glycerol, water, titaniumdioxide (E171),quinoloneyellow(E104),sunset The otheringredients ar The activesubstanceisclotrimazoleatastrength of500mg. Do notw Tr Tr pr Change yoursanitary After goingtothetoilet,wipeyourselffr Wash daily Wear cottonknick

FURTHERINFORMATION y toavoidwashing withperfumedsoapsorusingvaginal deodorants. y toavoidwearingtights, nylonknickers andclosefittingjeans. ash orrubyourselfhard withspongesorflannelsandavoidhot . o notuse’ and‘Important informationaboutsomeof the ers andlooseclothing. otection regularly. e benzylalcohol,polysorbate60,sorbitan e whitesoftparaffin, liquidparaffin, gelatin, om thefront tobackasathrush /w. 86148161 05.12.17 10:59

Black

Pantone 485 U

Pantone Cool CAN Soft Gel Pessary Combi GB Gray 11 U

210 x 297 mm

Kontur

Verlag Book, Book Italic, Bold, Bold Italic; Zapf Dingbats Regular; Bliss Pro Medium 9 pt