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Development of New Implant System for Correction of Coxofemoral Luxation in Canines

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Development of New Implant System for Correction of Coxofemoral Luxation in Canines Project Number: GRG-0901 DEVELOPMENT OF NEW IMPLANT SYSTEM FOR CORRECTION OF COXOFEMORAL LUXATION IN CANINES A Major Qualifying Report Submitted to the Faculty Of the WORCESTER POLYTECHNIC INSTITUTE In partial fulfillment of the requirements for the Degree of Bachelor of Science by Meghan Pasquali ________________________ Nicholas Pelletier ________________________ Jennifer Richards ________________________ Jonathan Shoemaker ________________________ Date: April 23, 2009 Approved: Prof. Glenn Gaudette, Advisor 1. Toggle rod _________________________ 2. Coxofemoral luxation 3. Novel implants Table of Contents Authorship .................................................................................................................................................... 5 Table of Figures ............................................................................................................................................ 6 Acknowledgements ....................................................................................................................................... 8 1 Abstract ................................................................................................................................................. 9 2 Introduction ......................................................................................................................................... 10 3 Background ......................................................................................................................................... 12 3.1 Anatomy of a Dog ....................................................................................................................... 12 3.2 Coxofemoral Luxation ................................................................................................................ 15 3.3 Treatment .................................................................................................................................... 18 4 Project Approach ................................................................................................................................ 24 4.1 Initial Client Statement ............................................................................................................... 24 4.2 Objectives ................................................................................................................................... 24 4.3 Functions ..................................................................................................................................... 25 4.4 Revised Client Statement ............................................................................................................ 26 4.5 Specific Aims – Project Specifications ....................................................................................... 26 4.6 Assumptions ................................................................................................................................ 28 5 Design ................................................................................................................................................. 29 5.1 Needs, Analysis & Specifications ............................................................................................... 29 5.2 Alternative Implant Designs ....................................................................................................... 31 5.3 Alternative Designs for Insertion Tool ....................................................................................... 42 5.4 Alternative Designs for Suture Sheath ........................................................................................ 44 5.5 Alternative Designs for Aiming Guide ....................................................................................... 48 5.6 Modeling ..................................................................................................................................... 52 5.7 Decisions ..................................................................................................................................... 54 5.8 Optimization ............................................................................................................................... 55 5.9 Preliminary Data ......................................................................................................................... 59 6 Methods............................................................................................................................................... 61 7 Results ................................................................................................................................................. 65 7.1 Suture Tensile Testing ................................................................................................................ 65 7.2 Implant ........................................................................................................................................ 68 7.3 Insertion Tool .............................................................................................................................. 69 7.4 Aiming Guide .............................................................................................................................. 70 2 7.5 Suture Sheath .............................................................................................................................. 71 8 Discussion ........................................................................................................................................... 72 8.1 Implant ........................................................................................................................................ 72 8.2 Insertion Tool .............................................................................................................................. 76 8.3 Aiming Guide .............................................................................................................................. 78 8.4 Suture Sheath .............................................................................................................................. 79 8.5 Economic Impact of θ De-Lux System ....................................................................................... 81 8.6 Environmental Impact ................................................................................................................. 81 8.7 Societal Influence ........................................................................................................................ 82 8.8 Political Ramifications ................................................................................................................ 82 8.9 Ethical Concern ........................................................................................................................... 83 8.10 Health and Safety ........................................................................................................................ 83 8.11 Manufacturability ........................................................................................................................ 83 8.12 Sustainability ............................................................................................................................... 84 9 Final Design Validation ...................................................................................................................... 85 10 Conclusions ..................................................................................................................................... 86 10.1 Double Theta Implant ................................................................................................................. 86 10.2 Insertion Tool .............................................................................................................................. 86 10.3 Suture Sheath .............................................................................................................................. 87 10.4 Aiming Guide .............................................................................................................................. 87 11 Recommendations ........................................................................................................................... 89 12 Works Cited .................................................................................................................................... 90 Appendix A: Glossary of Terms ................................................................................................................ 92 Appendix B: Pairwise Comparison Chart ................................................................................................... 94 Appendix C: Function Means Tree ............................................................................................................. 96 Appendix D: Interview with Dr. Seponoski ................................................................................................ 97 Appendix E: Interview with Dr. Flynn ....................................................................................................... 98 Appendix F: Interview with Dr. Ralphs .................................................................................................... 100 Appendix G: Preliminary Testing Protocol .............................................................................................. 101 Appendix
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