cancers Article Piperlongumine, a Potent Anticancer Phytotherapeutic, Induces Cell Cycle Arrest and Apoptosis In Vitro and In Vivo through the ROS/Akt Pathway in Human Thyroid Cancer Cells Fang-Ping Kung 1,†, Yun-Ping Lim 2,3,4,†, Wen-Ying Chao 5, Yi-Sheng Zhang 6, Hui-I Yu 1, Tsai-Sung Tai 1, Chieh-Hsiang Lu 1, Shu-Hsin Chen 6, Yi-Zhen Li 6, Pei-Wen Zhao 6, Yu-Pei Yen 1 and Ying-Ray Lee 7,* 1 Division of Endocrinology and Metabolism, Department of Internal Medicine, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chiayi 60002, Taiwan;
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[email protected] (S.-H.C.); Citation: Kung, F.-P.; Lim, Y.-P.;
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[email protected] (P.-W.Z.) Chao, W.-Y.; Zhang, Y.-S.; Yu, H.-I.; 7 Department of Microbiology and Immunology, School of Medicine, College of Medicine, Tai, T.-S.; Lu, C.-H.; Chen, S.-H.; Li, Kaohsiung Medical University, Kaohsiung 80708, Taiwan Y.-Z.; Zhao, P.-W.; et al.