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Op-001 Op-003 Op-002 TSC Abstracts/ORALS Anatol J Cardiol 2017; 18 (Suppl 1): 1-109 October 5-8, 2017 1 Arrhythmia / Electrophysiology / Pacemaker / CRT- ICD Table 1. Baseline characteristics and laboratory findings of the study population OP-001 Ventricular arrhythmias prediction in bodybuilders Kadir Uğur Mert, Muhammet Dural, Serdar İlgüy, Gurbet Özge Mert, Kemal İskenderov, Taner Ulus Department of Cardiology, Eskişehir Osmangazi University Faculty of Medicine, Eskişehir Background and Aim: Arrythmias are often recorded in strength training athletes without cardiovascular abnormalities but also may be a sign of an underlying cardiovascular disease which predicts risk of sud- den cardiac death(SCD). Nowadays, bodybuilding is a popular sport among adolescents. There was lack of studies comparing bodybuilders with healthy controls by excluding anabolics in arrythmias. We aimed to evaluate structural, functional and electrical characteristics of the bodybuilders’ heart comparing with control subjects. Methods: In this study, 35 male competitive bodybuilders and 35 age-, gender-, body mass index- matched healthy control subjects were evaluated. A detailed cardiovascular and systemic examination was per- formed at the beginning of the study with demographic data and anthropometric measures. Biochemical ACE: Angiotensin converting enzyme; ARB: Angiotensin receptor blocker; TSH: Thyroid-stimulating hormone. and haemotologic, echocardiographic, 24 h holter recordings, and ECG measurements obtained from all participants. Table 2. Conventional echocardiographic parameters and atrial conduction times Results: VAs encountered significantly more frequently in bodybuilders than control group (Table). QT and of the two groups QTc were not significantly different among groups. Tp-e interval, Tp-e/QT ratio, and Tp-e/QTc ratio were significantly higher in bodybuilders group compared to the control group (constantly p<0.001) (figure). There were a positive correlation between Tp-e interval, Tp-e/QT ratio, and Tp-e/QTc ratio with RV and arrythmias. Conclusions: Prolonged repolarization are common in athletes, even if their predictive value is unclear. In this study, alteration in ventricular repolarization were positively correlated with RV dimensions, thus we postulated that arrythmias, exclusively in strength athletes, may be predicted by evaluating RV echocardio- graphically and dispersions of repolarization in ECG. Finally, SCD could be evitable in strength athletes with this kind of reasonable and applicable interpretation. (a) (b) (c) Figure Table EMD: Electromechanical delay; LA: Left atrium; LV: Left ventricle; LVH: Left ventricular hypertrophy; PA: Time interval from the onset of P wave to the beginning of the late myocardial diastolic velocity; Pd P-wave disper- sion, Pmax maximum P-wave duration, Pmin: Minimum P-wave duration, PW: Posterior wall thickness; RA Right atrium; Vmax: Maximum volume; Vmin: Minimum volume. Arrhythmia / Electrophysiology / Pacemaker / CRT- ICD OP-003 Arrhythmia / Electrophysiology / Pacemaker / CRT- ICD OP-002 Electrocardiographic alterations in patients consuming synthetic cannabinoids Hayriye Mihrimah Öztürk,1 Mehmet Erdoğan,2 Yakup Alsancak,3 Mikail Yarlıoğlueş,2 Mustafa Duran,2 Mehmed Hamid Boztaş,4 Sani Namık Murat,2 Selçuk Öztürk2 Atrial conduction time in patients with pseudoexfoliation syndrome 1Department of Psychiatry, Ankara Numune Training and Research Hospital, Ankara 1 1 1 2 Taner Ulus, Kamal Isgandarov, Sayyed Hamed Moghanchızadeh, Merve Bozkurt, 2Department of Cardiology, Ankara Numune Training and Research Hospital, Ankara 3 2 Fezan Mutlu, Nilgün Yildirim 3Department of Cardiology, Ankara Atatürk Training and Research Hospital, Ankara 1Department of Cardiology, Eskişehir Osmangazi University Faculty of Medicine, Eskişehir 4Abant İzzet Baysal University Mental Health and Diseases Training and Research Hospital, Bolu 2 Department of Ophthalmology, Eskişehir Osmangazi University Faculty of Medicine, Eskişehir Background and Aim: Synthetic cannabinoids (SCs) are chemical products imitating the effect of tetrahy- 3 Department of Biostatistics, Eskişehir Osmangazi University Faculty of Medicine, Eskişehir drocannabinol (THC), which is derived from the cannabis plant and consist the primary psychoactive com- Background and Aim: Pseudoexfoliation (PEX) syndrome is a common disorder of the extracellular matrix. ponent. SCs were first defined in Europe in 2008 and over the years their popularity has increased. Until Some studies have showed an association between PEX syndrome and an increased risk for cardiovascu- now, more than one hundred class of agents belonging to this group has been defined. There is little data lar and cerebrovascular diseases. Atrial fibrillation is a major cause of ischemic strokes. There is no data about the cardiovascular effects of SCs, mainly including case reports presenting with myocardial infarc- related to any association between PEX syndrome and increased risk of AF. The deposition of PEX mate- tion (MI) or sudden cardiac death after SC consumption. The exact mechanism causing cardiovascular rial in myocardium, altered function of calcium channel or alterations of calcium concentration in tissue, event is not known. The aim of this study was to investigate the electrocardiographic parameters in patients increased oxidative stress, elevated plasma homocysteine levels were found in PEX patiens. All of them consuming SCs. increase the risk of AF. Impaired left atrial electrical function plays a significant role in the development of Methods: 35 patients who were consuming SCs were enrolled to the study, prospectively. The control group AF. This study aimed to evaluate the atrial electromechanical delay (EMD) in patients with PEX. included 35 healthy age and sex-matched volunteers. The standard 12-lead surface ECGs of the study popu- Methods: Thirty-four PEX patients and 29 age-matched and sex-matched healthy controls were included. lation were recorded. P maximum (Pmax), P minimum (Pmin), P wave dispersion (PWD), interatrial duration, Fasting blood samples were taken and the following data were obtained from all cases: A 12-lead surface P wave area in D2 derivation, abnormal P terminal force in V1 derivation, heart rate, QT duration, corrected electrocardiogram to evaluate P-wave duration and dispersion (Pd), a tissue Doppler echocardiography to QT (QTc), QT dispersion (QTd), PR interval duration and macrovolt T-wave alternans were evaluated by determine the atrial conduction and EMD time, left atrium maximum and minimum volumes. two experienced cardiologists. The intra-observer and inter-observer variations for all measurements were Results: Pmaximum [100 ms (100-120) vs. 90 ms (80-100), p<0.001] and Pd [40 ms (40-60) vs. 30 ms (20-40), non-significant. p<0.001] were higher in patients with PEX than in controls. Tissue Doppler echocardiography measurements Results: Pmax and Pmin duration was not different between the groups (p=0.96, p=0.15, respectively). How- showed PA lateral, PA septal and PA tricuspid were higher in patients with PEX than in controls (p<0.001, ever, PWD was higher in the patient group compared to control group (34±9.4, 29.5±6.6, p=0.02, respec- 0.010 and 0.021, respectively). Interatrial EMD [39.00 ms (28.00-44.00) vs 28.00 ms (23.50-33.00), p=0.001] and tively). QT duration was significantly higher in the patient group than the control group (380.3±25, 365.6±22.8, intra-left atrial EMD [17.00 ms (15.00-23.25) vs 11.00 ms (10.00-17.50), p=0.003] were higher in patients with p=0.01,respectively). Besides, QTc duration was higher in the patient group compared to control group PEX. Left atrial volumes were similar between the groups. (415±36.8, 392±15.5, p=0.001, respectively). QTd was also higher in the patient group than the control group Conclusions: Echocardiographic atrial EMD indices, Pmax and Pd were significantly increased in PEX pa- (39.8±10.0, 29.2±5.4, p<0.001, respectively). tients with normal cardiac function. These results suggest that PEX patients may have an increased risk Conclusions: Patients consuming SC are at high risk for developing atrial and ventricular arrhythmias. These of AF. Further long-term follow-up studies are needed to investigate whether the risk of developing AF is patients should be evaluated regularly for CVD and arrhythmia development. ECG, which is a cheap and easy increased in patients with PEX. test to apply, can be used to determine the proarrythmic risk in patients consuming SC. TSC Abstracts/ORALS 2 October 5-8, 2017 Anatol J Cardiol 2017; 18 (Suppl 1): 1-109 Table 1. Demographical, Clinical, and Biochemical values Figure 1. QT measurements of the study groups. Figure 2. P wave and QT dispersion measure- ments of the study groups. Arrhythmia / Electrophysiology / Pacemaker / CRT- ICD OP-005 Prevalence and characteristics of inappropriate sinus tachycardia in the outpatient clinic of a tertiary hospital * Control group vs Pre-DM group, ** Pre-DM group vs DM group ACEI: angiotensin converting enzyme inhibitor, ARB: angiotensin receptor blocker, BMI: Body mass index, CCB: calcium channel blocker, DU: 1 1 1 1 1 Evrim Şimşek, Benay Özbay, Inan Mutlu, Emir Baskovski, Ecem Gürses, diuretic, FBG: Fasting blood glucose, HDL-C: High density lipoprotein cholesterol, LDL-C: Low density lipo- Hatice Soner Kemal,2 Cemil Gürgün1 protein cholesterol, TC: Total cholesterol, TG: Triglycerides. 1Department of Cardiology, Ege University Faculty of Medicine, İzmir Table 2. Heart rate variability parameters 2Department of Cardiology, Near
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