B4GALT2 Antibody Cat. No.: 16-989

B4GALT2 Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 155-271 IMMUNOGEN: of human B4GALT2 (NP_085076.2).

TESTED APPLICATIONS: IHC, WB

WB: ,1:500 - 1:2000 APPLICATIONS: IHC: ,1:100 - 1:200

POSITIVE CONTROL: 1) U-87MG

2) PC-3

3) OVCAR3

4) HT-29

5) Mouse brain

6) Mouse skeletal muscle

PREDICTED MOLECULAR Observed: 42kDa WEIGHT:

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PURIFICATION: Affinity purification

CLONALITY: Polyclonal

ISOTYPE: IgG

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

Additional Info

OFFICIAL SYMBOL: B4GALT2

Beta-1,4-galactosyltransferase 2, Beta-1,4-GalTase 2, Beta4Gal-T2, b4Gal-T2, 241-, UDP- Gal:beta-GlcNAc beta-1,4-galactosyltransferase 2, UDP-galactose:beta-N- acetylglucosamine beta-1,4-galactosyltransferase 2, Lactose synthase A protein, N- ALTERNATE NAMES: acetyllactosamine synthase, Nal synthase, Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase, Beta-N-acetylglucosaminyl- beta-1,4- galactosyltransferase, 241-, B4GALT2

GENE ID: 8704

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

This is one of seven beta-1,4-galactosyltransferase (beta4GalT) . They encode type II membrane-bound that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to BACKGROUND: the and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The encoded by this gene synthesizes N-acetyllactosamine in and glycoproteins. Its substrate specificity is affected by alpha-lactalbumin but it is not expressed in lactating mammary tissue. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]

ANTIBODIES FOR RESEARCH USE ONLY.

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