Artificial Sweeteners That Substance Or a Viable Are Used in Food and Drink Alternative to Sugar, There Across the World
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Popular Sweeteners and Their Health Effects Based Upon Valid Scientific Data
Popular Sweeteners and Their Health Effects Interactive Qualifying Project Report Submitted to the Faculty of the WORCESTER POLYTECHNIC INSTITUTE in partial fulfillment of the requirements for the Degree of Bachelor of Science By __________________________________ Ivan Lebedev __________________________________ Jayyoung Park __________________________________ Ross Yaylaian Date: Approved: __________________________________ Professor Satya Shivkumar Abstract Perceived health risks of artificial sweeteners are a controversial topic often supported solely by anecdotal evidence and distorted media hype. The aim of this study was to examine popular sweeteners and their health effects based upon valid scientific data. Information was gathered through a sweetener taste panel, interviews with doctors, and an on-line survey. The survey revealed the public’s lack of appreciation for sweeteners. It was observed that artificial sweeteners can serve as a low-risk alternative to natural sweeteners. I Table of Contents Abstract .............................................................................................................................................. I Table of Contents ............................................................................................................................... II List of Figures ................................................................................................................................... IV List of Tables ................................................................................................................................... -
Full Assessment Report. (Word5)
ATTACHMENT 3 SAFETY ASSESSMENT REPORT APPLICATION A406 PERMISSION FOR USE OF NEOTAME SUMMARY Introduction The NutraSweet Company is seeking approval for the use of a new artificial sweetener (Neotame) in Australia and New Zealand. The proposed uses include, but are not limited to, soft drink beverages (both carbonated and non-carbonated), beverage concentrates, beverage mixes, dairy beverages, fruit juice products, alcoholic drinks, non-dairy desserts, gelatin, ice cream, breakfast cereals and as a tabletop sweetener for use in hot beverages such as tea or coffee. Neotame (L-phenylalanine, N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-,1-methyl ester; or NC- 00723) is a dipeptide methyl ester derivative, chemically-related to aspartame. It has a sweetness potency of 7000 to 13,000-times sweeter than sucrose, and 30 to 60-times that of aspartame, depending on the use. Neotame was very stable in mock beverage solutions simulating commercial formulations. The only degradation product formed at >1% was L-phenylalanine, N-[N-3,3-dimethylbutyl)- L-α-aspartyl (NC-00751), which is also the major metabolite in both animals and humans and other minor degradation products (each <1%) which are not expected to be detectable at actual use levels of Neotame. Metabolism and toxicokinetics A number of studies on the metabolism and toxicokinetics were performed in rats and dogs, mainly via the oral route, although the intravenous route was also investigated. Neotame was rapidly absorbed following oral dosing, with around 14% of the administered dose absorbed in a pilot metabolism study and around 20-30% absorbed in the definitive rat metabolism study. -
The Reality of Artificial Sweeteners
Review Article Curre Res Diabetes & Obes J Volume 7 Issue 2 - May 2018 Copyright © All rights are reserved by Rafia Bano DOI: 10.19080/CRDOJ.2018.07.555708 The Reality of Artificial Sweeteners Rafia Bano* Department of Clinical Nutrition, College of Applied medical Sciences, University of Hail, Saudi Arabia Submission: April 04, 2018; Published: May 09, 2018 *Corresponding author: Rafia Bano, Department of Clinical Nutrition, College of Applied medical Sciences, University of Hail, HAIL, KSA, Saudi Arabia, Email: Abstract Now a days we are facing serious obesity issues worldwide. More than half of people in the US are becoming overweight, of which more than half are obese. As a result the weight related disorders are on the rise. So with all of these weight related problems going around, increased number of people struggling with weight lost regimens. They are trying to change their eating habits to include more vegetables and whole grains in their diets. They’re trying to be more physically active. They’re trying to modify snacking choices to healthier ones. There has been found an increasing trend of substituting artificial sweeteners in the sweet snacks and drinks that make up the majority of the American diet. But the question is that - are these substitutes really going to help? Or are they going to do more harm than benefit? The research has shown mixed evidences, but more and more is showing that these artificial sweeteners are not a good substitute. Artificial sweeteners continue to be a controversial public health issue, and the research keeps coming. At one side, many people are strongly opposing the use of artificial sweeteners because of the reported connections with increased risk for cancer and other metabolic and degenerative diseases. -
Clean Label Alternatives in Meat Products
foods Review Clean Label Alternatives in Meat Products Gonzalo Delgado-Pando 1 , Sotirios I. Ekonomou 2 , Alexandros C. Stratakos 2 and Tatiana Pintado 1,* 1 Institute of Food Science, Technology and Nutrition (CSIC), José Antonio Novais 10, 28040 Madrid, Spain; [email protected] 2 Centre for Research in Biosciences, Coldharbour Lane, Faculty of Health and Applied Sciences, University of the West of England, Bristol BS16 1QY, UK; [email protected] (S.I.E.); [email protected] (A.C.S.) * Correspondence: [email protected] Abstract: Food authorities have not yet provided a definition for the term “clean label”. However, food producers and consumers frequently use this terminology for food products with few and recognisable ingredients. The meat industry faces important challenges in the development of clean-label meat products, as these contain an important number of functional additives. Nitrites are an essential additive that acts as an antimicrobial and antioxidant in several meat products, making it difficult to find a clean-label alternative with all functionalities. Another important additive not complying with the clean-label requirements are phosphates. Phosphates are essential for the correct development of texture and sensory properties in several meat products. In this review, we address the potential clean-label alternatives to the most common additives in meat products, including antimicrobials, antioxidants, texturisers and colours. Some novel technologies applied for the development of clean label meat products are also covered. Keywords: clean label; meat products; nitrites alternatives; phosphates alternatives Citation: Delgado-Pando, G.; Ekonomou, S.I.; Stratakos, A.C.; Pintado, T. -
Sweet Sensations by Judie Bizzozero | Senior Editor
[Confections] July 2015 Sweet Sensations By Judie Bizzozero | Senior Editor By R.J. Foster, Contributing Editor For many, terms like “reduced-sugar” or “sugar-free” do not go with the word “candy.” And yet, the confectionery industry is facing growing demand for treats that offer the taste people have grown to love without the adverse health effects they’re looking to avoid. Thankfully, there is a growing palette of ingredients from which candy makers can paint a new picture of sweetness that will be appreciated by the even most discerning of confectionery critics. SUGAR ALCOHOLS Also referred to as polyols, sugar alcohols are a common ingredient in reduced-sugar and sugar-free applications, especially confections. Funny thing, they’re not sugars or alcohols. Carbohydrate chains composed of monomeric, dimeric and polymeric units, polyols resemble both sugars and alcohols, but do not contain an ethanol molecule. All but two sugar alcohols are less sweet than sugar. Being only partially digestible, though, replacing a portion of a formulation’s sugar with a sugar alcohol reduces total calories without losing bulk (which can occur when replacing sugar with high-intensity sweeteners). Unique flavoring, texturizing and moisture-controlling effects also make polyols well-suited for confectionery products. Two very common and very similar monomeric polyols are sorbitol and mannitol. Present in a variety of fruits and vegetables, both are derived from products of cornstarch hydrolysis. Sorbitol is made via hydrogenation of glucose, which is why sorbitol is sometimes referred to as glucitol. Mannitol is created when fructose hydrogenation converts fructose into mannose, for which the final product, mannitol, is named. -
Chemical Basics of Life
© Jones & Bartlett Learning, LLC. NOT FOR SALE OR DISTRIBUTION CHAPTER 2 Chemical Basics of Life OUTLINE KEY TERMS Atoms, Molecules, and Chemical Bonds Acids: Electrolytes that release hydrogen ions in water. Atomic Structure Activation energy: The amount of energy required to start a Molecules reaction. Chemical Bonds Anions: Ions with a negative charge. Types of Chemical Reactions Atomic number: A whole number representing the number Enzymes of positively charged protons in the nucleus of an atom. Acids, Bases, and the pH Scale Atomic weight: The total number of protons and neutrons in Chemical Constituents of Cells the nucleus of an atom. Inorganic Substances Atoms: The smallest complete units of an element, varying in Organic Substances size, weight, and interaction with other atoms. Summary Bases: Electrolytes that release ions that bond with Learning Goals hydrogen ions. Critical Thinking Questions Carbohydrates: Substances (including sugars) that provide Websites much of the energy required by the body’s cells, as well as Review Questions helping to build cell structures. Catalysts: Atoms or molecules that can change the rate of a OBJECTIVES reaction without being consumed during the process. After studying this chapter, readers should be able to: Cations: Ions with a positive charge. 1. Describe the relationships between atoms and Chemistry: The study of the composition of matter and molecules. changes in its composition. 2. Explain chemical bonds. Compounds: Molecules made up of different bonded atoms. 3. Describe how an atomic number is determined. Decomposition: A reaction that occurs when bonds with a 4. List the major groups of inorganic chemicals reactant molecule break, forming simpler atoms, molecules, common in cells. -
Nutrasweet and Laidlaw Bruce M. Graham*
Abuse of Dominance - Recent Case Law: Nutrasweet and Laidlaw Bruce M. Graham* Nutrasweet and Laidlaw are the Competi- Dans Nutrasweet et Laidlaw, le Tribunal de tion Tribunal's first two decisions applying the Ia concurrence aborda les dispositions de Ia abuse of dominant position provisions of the Loi sur la concurrence en mati~re d'abus de Competition Act. The author undertakes an in position dominante. L'auteur nous livre une depth analysis of these two decisions. His 6tude ddtdill6e de ces deux d6cisions. II exa- comments explore tensions in the goals pur-, mine certaines tensions qui existent dans les sued by competition law and call into question objectifs vis6s par le droit de la concurrence et the approach adopted by the Tribunal in these remet en question l'opportunit6 de l'approche cases. The author argues that the Tribunal pr6conis6e par le Tribunal, qui, selon l'auteur, underestimated the disciplining power of the a sous-estim6 le pouvoir du march6 de corriger market in these decisions and closes with lui-m~me les abus. L'auteur conclut en offrant advice to corporate counsel advising large des conseils aux avocats appel6s A guider le firms on how to conduct themselves in light of comportement des grandes compagnies DLla Nutrasweet and Laidlaw. lumi~re de ces deux d6cisions. *Partner, Smith, Lyons, Torrance, Stevenson & Mayer. © McGill Law Journal 1993 Revue de droit de McGill To be cited as: (1993) 38 McGill L.L 800 Mode de r6fdrence: (1993) 38 R.D. McGill 800 1993] NUTRASWEET AND LAIDLAW Synopsis Introduction 1. The Case Law A. -
Aspartame—True Or False? Narrative Review of Safety Analysis of General Use in Products
nutrients Review Aspartame—True or False? Narrative Review of Safety Analysis of General Use in Products Kamila Czarnecka 1,2,*, Aleksandra Pilarz 1, Aleksandra Rogut 1, Patryk Maj 1, Joanna Szyma ´nska 1, Łukasz Olejnik 1 and Paweł Szyma ´nski 1,2,* 1 Department of Pharmaceutical Chemistry, Drug Analyses and Radiopharmacy, Faculty of Pharmacy, Medical University of Lodz, Muszy´nskiego1, 90-151 Lodz, Poland; [email protected] (A.P.); [email protected] (A.R.); [email protected] (P.M.); [email protected] (J.S.); [email protected] (Ł.O.) 2 Department of Radiobiology and Radiation Protection, Military Institute of Hygiene and Epidemiology, 4 Kozielska St., 01-163 Warsaw, Poland * Correspondence: [email protected] (K.C.); [email protected] (P.S.); Tel.: +48-42-677-92-53 (K.C. & P.S.) Abstract: Aspartame is a sweetener introduced to replace the commonly used sucrose. It was discovered by James M. Schlatter in 1965. Being 180–200 times sweeter than sucrose, its intake was expected to reduce obesity rates in developing countries and help those struggling with diabetes. It is mainly used as a sweetener for soft drinks, confectionery, and medicines. Despite its widespread use, its safety remains controversial. This narrative review investigates the existing literature on the use of aspartame and its possible effects on the human body to refine current knowledge. Taking to account that aspartame is a widely used artificial sweetener, it seems appropriate to continue Citation: Czarnecka, K.; Pilarz, A.; research on safety. Studies mentioned in this article have produced very interesting results overall, Rogut, A.; Maj, P.; Szyma´nska,J.; the current review highlights the social problem of providing visible and detailed information about Olejnik, Ł.; Szyma´nski,P. -
An Integrated Approach to Understand Apicomplexan Metabolism From
Shanmugasundram et al. BMC Bioinformatics 2014, 15(Suppl 3):A3 http://www.biomedcentral.com/1471-2105/15/S3/A3 MEETINGABSTRACT Open Access An integrated approach to understand apicomplexan metabolism from their genomes Achchuthan Shanmugasundram1,2*, Faviel F Gonzalez-Galarza1, Jonathan M Wastling2, Olga Vasieva1, Andrew R Jones1 From Ninth International Society for Computational Biology (ISCB) Student Council Symposium 2013 Berlin, Germany. 19 July 2013 Background Methods The Apicomplexa is a large phylum of intracellular para- We have utilised an approach called ‘metabolic recon- sites that show great diversity and adaptability in the struction’, in which genes are systematically assigned to various ecological niches they occupy. They are the cau- functions within pathways/networks [1-4]. Functional sative agents of human and animal infections including annotation and metabolic reconstruction was carried malaria, toxoplasmosis and theileriosis, which have a out using a semi-automatic approach, integrating geno- huge economic and social impact. A number of apicom- mic information with biochemical evidence from the plexan genomes have been sequenced and are publicly literature. The functions were automatically assigned available. However, the prediction of gene models and using a sequence similarity-based approach and protein annotation of gene functions remains challenging. motif information. Experimental evidence was also Table 1 A survey of the data available for the different apicomplexan genomes in LAMP. The analysis is updated from the survey table published in the previous publication [5] Organism No of metabolic No of unique No of missing No of Total no of No of metabolites No of end pathways enzymesa enzymesb reactionsc metabolitesd from hoste metabolites to host or of unknown fatef T. -
The Effect of Using E-Numbers Or Colloquial Additive Names on the Consumption Intention
The effect of using E-numbers or colloquial additive names on the consumption intention. Master thesis Author: Ron Hoogma Supervisor: Arnout Fischer Coreader: Ivo van der Lans Chairgroup: Marketing and Consumer Behaviour Date: 2015 The effect of using E-numbers or colloquial additive names on the consumption intention. Table of content Abstract ................................................................................................................................................... 3 Introduction ............................................................................................................................................. 4 Theoretical background ........................................................................................................................... 6 Risk & Benefit perception .................................................................................................................... 6 Understanding and perceiving additives ............................................................................................. 7 Methodology ......................................................................................................................................... 10 Operationalization ............................................................................................................................. 10 Pre-test .............................................................................................................................................. 11 Main study ........................................................................................................................................ -
Aspartame | European Food Safety Authority
5/17/2017 Aspartame | European Food Safety Authority Home Topics AZ Aspartame Aspartame Aspartame is a lowcalorie, intense artificial sweetener. It is a white, odourless powder, approximately 200 times sweeter than sugar. In Europe, it is authorised to be used as a food additive in foodstuffs such as drinks, desserts, sweets, dairy, chewing gums, energyreducing and weight control products and as a tabletop sweetener. The sweetener aspartame and its breakdown products have been a matter of extensive investigation for more than 30 years including experimental animal studies, clinical research, intake and epidemiological studies and postmarketing surveillance. It has been found to be safe and authorised for human consumption for many years and in many countries following thorough safety assessments. In the European Union (EU) the label on foodstuffs containing aspartame must state its presence, indicating either its name or its E number (E 951). Activities Role EU framework FAQ Completed work Since 2002, EFSA has kept the safety of aspartame under regular review and its Scientific Panels have issued several opinions on studies related to this sweetener. Currently, this work is carried out by the Panel on Food Additives and Nutrient Sources Added to Food (ANS). Latest activities In December 2013 EFSA published its first full risk assessment of aspartame. The opinion concludes that aspartame and its breakdown products are safe for general population (including infants, children and pregnant women). The current Acceptable Daily Intake (ADI) of 40mg/kg bw/day is considered protective for the general population and consumer exposure to aspartame is well below this ADI. -
Food Additives
Food additives Department of Chemistry The Open University of Sri Lanka 1 Published by The Open University of Sri Lanka 2014 Food additives Introduction In previous lessons, we considered the chemistry of synthetic polymers, natural polymers and biomolecules such as carbohydrates, amino acids, proteins, fatty acids and lipids. In this lesson, we intend to study pros and cons of food additives. People around the world use natural and artificial food additives particularly to improve the taste and appearance of food without thinking of their effects on their health. Do you have the practice of checking the list of food additives given in the label when you buy food items? Centuries ago and even today people smoke fish/meat and add certain chemicals to them (e.g. salt) to improve their shelf life. Particularly in eastern countries, people add spices and indigenous herbs to food to improve its taste and colour. Some food varieties are seasonal (and abundant during the season) and are not available throughout the year. But preserved food is made available around the year, enabling us to enjoy food in different forms, even in places where it is not available or produced. Consumption of food additives may have certain health risks. Carcinogenesis (i.e. causation of cancers), hyperactivity in children, precipitation of allergies, and migraine are some known health risks associated with food additives. It is high time you knew more about what you eat. Let us examine the definition of a food additive. Food additives can be defined as chemical substances deliberately added to food, directly or indirectly, in known or regulated quantities, for purposes of assisting in the processing of food, preservation of food, or in improving the flavour, texture, or appearance of food.