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Microdosing Psychedelics: Results from the Global Drug Survey 2019
Microdosing Psychedelics: Results from the Global Drug Survey 2019 Petranker, R.1,2, Anderson, T.2,3, Maier, L. J.4,5, Barratt, M. J.6,7, Ferris, J. A.8, & Winstock, A. R.9,10 1 Clinical Psychology, York University, Toronto, ON, Canada 2 Psychedelic Studies Research Program, University of Toronto Mississauga, Mississauga, ON, Canada 3 Department of Psychology, University of Toronto, Toronto, ON, Canada. 4 Department of Psychiatry and Weill Institute for Neurosciences, University of California, San Francisco, CA, United States 5 Early Postdoc Mobility Grantee, Swiss National Science Foundation, Bern, Switzerland 6 Social and Global Studies Centre, RMIT University, Australia 7 National Drug and Alcohol Research Centre, UNSW Sydney, Australia 8 Centre for Health Services Research, Faculty of Medicine, The University of Queensland, Brisbane, Australia 9 University College London, Gower St, Bloomsbury, London, UK 10 Global Drug Survey Ltd, London, UK *Corresponding Author Rotem Petranker Toronto, ON, Canada Email: [email protected] Abstract Microdosing psychedelics – the practice of taking small, sub-hallucinogenic amounts of substances like psilocybin-containing mushrooms or LSD – is becoming increasingly popular. Despite its surging popularity, little is known about the effects of this practice. This research had two aims. First, we attempted to replicate previous findings in the literature regarding the subjective benefits and challenges involved in microdosing. Second, we wanted to examine whether people who microdose test their substances for purity before consumption, and whether approach-intention to microdosing was predictive of more reported benefits. 7,313 people who reported microdosing, from a variety of countries, ages, and other demographics participated in our survey. -
Psilocybin Mushrooms Fact Sheet
Psilocybin Mushrooms Fact Sheet January 2017 What are psilocybin, or “magic,” mushrooms? For the next two decades thousands of doses of psilocybin were administered in clinical experiments. Psilocybin is the main ingredient found in several types Psychiatrists, scientists and mental health of psychoactive mushrooms, making it perhaps the professionals considered psychedelics like psilocybin i best-known naturally-occurring psychedelic drug. to be promising treatments as an aid to therapy for a Although psilocybin is considered active at doses broad range of psychiatric diagnoses, including around 3-4 mg, a common dose used in clinical alcoholism, schizophrenia, autism spectrum disorders, ii,iii,iv research settings ranges from 14-30 mg. Its obsessive-compulsive disorder, and depression.xiii effects on the brain are attributed to its active Many more people were also introduced to psilocybin metabolite, psilocin. Psilocybin is most commonly mushrooms and other psychedelics as part of various found in wild or homegrown mushrooms and sold religious or spiritual practices, for mental and either fresh or dried. The most popular species of emotional exploration, or to enhance wellness and psilocybin mushrooms is Psilocybe cubensis, which is creativity.xiv usually taken orally either by eating dried caps and stems or steeped in hot water and drunk as a tea, with Despite this long history and ongoing research into its v a common dose around 1-2.5 grams. therapeutic and medical benefits,xv since 1970 psilocybin and psilocin have been listed in Schedule I of the Controlled Substances Act, the most heavily Scientists and mental health professionals criminalized category for drugs considered to have a consider psychedelics like psilocybin to be “high potential for abuse” and no currently accepted promising treatments as an aid to therapy for a medical use – though when it comes to psilocybin broad range of psychiatric diagnoses. -
Community and Practice in Two Generations of Online Illicit Drugs Discussions
Community and practice in two generations of online illicit drugs discussions A thesis submitted to the University of Manchester for the degree of Doctor of Philosophy in the Faculty of Humanities. 2020 P. O. Enghoff School of Social Sciences, Department of Criminology and Criminal Justice Table of Contents Abstract .................................................................................................................. 5 Acknowledgements .............................................................................................. 8 Other acknowledgements .................................................................................... 9 The author .............................................................................................................. 9 Chapter 1. Introduction ..................................................................................... 10 1.1 Background ........................................................................................... 11 1.2 Summary of thesis contents ................................................................ 19 1.2.1 Literature review .......................................................................... 20 1.2.2 Research design ............................................................................. 24 1.2.3 Research papers ............................................................................ 28 1.2.4 Discussion ...................................................................................... 31 Chapter 2. Literature review ............................................................................ -
BC2019-Printproginccovers-High.Pdf
CONTENTS Welcome with Acknowledgements 1 Talk Abstracts (Alphabetically by Presenter) 3 Programme (Friday) 32–36 Programme (Saturday) 37–41 Programme (Sunday) 42–46 Installations 47–52 Film Festival 53–59 Entertainment 67–68 Workshops 69–77 Visionary Art 78 Invited Speaker & Committee Biographies 79–91 University Map 93 Area Map 94 King William Court – Ground Floor Map 95 King William Court – Third Floor Map 96 Dreadnought Building Map (Telesterion, Underworld, Etc.) 97 The Team 99 Safer Spaces Policy 101 General Information 107 BREAK TIMES - ALL DAYS 11:00 – 11:30 Break 13:00 – 14:30 Lunch 16:30 – 17:00 Break WELCOME & ACKNOWLEDGEMENTS WELCOME & ACKNOWLEDGEMENTS for curating the visionary art exhibition, you bring that extra special element to BC. Ashleigh Murphy-Beiner & Ali Beiner for your hard work, in your already busy lives, as our sponsorship team, which gives us more financial freedom to put on such a unique event. Paul Callahan for curating the Psychedelic Cinema, a fantastic line up this year, and thanks to Sam Oliver for stepping in last minute to help with this, great work! Andy Millns for stepping up in programming our installations, thank you! Darren Springer for your contribution to the academic programme, your perspective always brings new light. Andy Roberts for your help with merchandising, and your enlightening presence. Julian Vayne, another enlightening and uplifting presence, thank you for your contribution! To Rob Dickins for producing the 8 circuit booklet for the welcome packs, and organising the book stall, your expertise is always valuable. To Maria Papaspyrou for bringing the sacred feminine and TRIPPth. -
Psychedelics in Psychiatry: Neuroplastic, Immunomodulatory, and Neurotransmitter Mechanismss
Supplemental Material can be found at: /content/suppl/2020/12/18/73.1.202.DC1.html 1521-0081/73/1/202–277$35.00 https://doi.org/10.1124/pharmrev.120.000056 PHARMACOLOGICAL REVIEWS Pharmacol Rev 73:202–277, January 2021 Copyright © 2020 by The Author(s) This is an open access article distributed under the CC BY-NC Attribution 4.0 International license. ASSOCIATE EDITOR: MICHAEL NADER Psychedelics in Psychiatry: Neuroplastic, Immunomodulatory, and Neurotransmitter Mechanismss Antonio Inserra, Danilo De Gregorio, and Gabriella Gobbi Neurobiological Psychiatry Unit, Department of Psychiatry, McGill University, Montreal, Quebec, Canada Abstract ...................................................................................205 Significance Statement. ..................................................................205 I. Introduction . ..............................................................................205 A. Review Outline ........................................................................205 B. Psychiatric Disorders and the Need for Novel Pharmacotherapies .......................206 C. Psychedelic Compounds as Novel Therapeutics in Psychiatry: Overview and Comparison with Current Available Treatments . .....................................206 D. Classical or Serotonergic Psychedelics versus Nonclassical Psychedelics: Definition ......208 Downloaded from E. Dissociative Anesthetics................................................................209 F. Empathogens-Entactogens . ............................................................209 -
Hallucinogenic Mushrooms: a Guide
Hallucinogenic Mushrooms: A Guide Presented by the Hamre Center for Health and Wellness Table of Contents Introduction Harm Reduction What are Hallucinogenic Mushrooms? What are the U.S. and MN Laws Surrounding Mushrooms? What Kinds of Hallucinogenic Mushrooms are There? How are Hallucinogenic Mushrooms Ingested? How Do Hallucinogenic Mushrooms Affect the Brain? What are Some Short-Term Effects of Use? What are Some Long-Term Effects of Use? How Do Hallucinogenic Mushrooms Interact with Alcohol? What are Some Harm-Reduction Strategies for Use? Are Hallucinogenic Mushrooms Addictive? What are Some Substance Abuse Help Resources? Introduction Welcome to the Hamre Center’s hallucinogenic mushrooms guide! Thank you for wanting to learn more about “magic mushrooms” and how they can affect you. This guide is designed to be a science-based resource to help inform people about hallucinogenic mushrooms. We use a harm-reduction model, which we’ll talk about more in the next slide. If you have any concerns regarding your own personal health and mushrooms, we strongly recommend that you reach out to your health care provider. No matter the legal status of hallucinogenic mushrooms in your state or country, health care providers are confidential resources. Your health is their primary concern. Harm Reduction ● The harm reduction model used in this curriculum is about neither encouraging or discouraging use; at its core, harm reduction simply aims to minimize the negative consequences of behaviors. ● Please read through the Hamre Center’s statement on use and harm reduction below: “The Hamre Center knows pleasure drives drug use, not the avoidance of harm. -
The Production of Psilocybin in Submerged Culture by Psilocybe Cubensis
The Production of Psilocybin in Submerged Culture by Psilocybe cubensis PHILIP CATALF01!O' AND V. E. TYLER, JR. (Drug Plant Laboratory, College of Pharmacy, University of Washington, Seattle 5) Psychotomimetic mushrooms have long been employed as intoxicants by vari- ous native peoples. Schultes (10) describes their employment in magico-religious ceremonies by the Indians of Mexico and Central America, and extensive docu- mentation of such usage has been provided by the Wassons (14, 15) and by Heim and Wasson (6). Especially noteworthy is the occurrence of certain indole derivatives in many of the basidiomycetes to which psychotomimetic properties have been ascribed. Several species of Panaeolus contain serotonin (o-hydroxytryptamine), first demonstrated in a fungus, Panaeolus campanulatus (Fr.) Quel., by Tyler (13). Bufotenine (5-hydroxy-N,lV-dimethyltryptamine) was shown to exist in Amanita citrina (Shaeff.) S. F. Gray [Amanita mappa (Lasch) Quel.] by Wieland and Motzel (16). Psilocybin (4-phosphoryl-N,N-dimethyltryptamine), together with the closely related psilocin (4-hydroxy-1Y,N-dimethyltryptamine), was first found in Psilocybe species by Hofmann, et al. (8).The latter two principles are the most recently discovered hallucinogens in basidiomycetes and are of particular interest since they are the only principles isolated from mushrooms 'w-hichare capable of inducing psychotomimetic effects in human beings following oral ingestion. Heim, et al.(7), established conditions favoring the formation of both sclerotia and sporocarps from mycelial growth obtained upon subculture of the spores and tissue of the naturally occurring Mexican Psilocybe species. In this way they obtained ample amounts of materials for isolation and structural studies of the active principles. -
FACTS About DRUGS: PSILOCYBIN (“Magic Mushrooms”)
Educate Yourself FACTS about DRUGS: PSILOCYBIN (“Magic Mushrooms”) WHAT IS IT? THE RISKS Psilocybin is a naturally occurring hallucinogen found in over one The risk of death from psilocybin overdose is hundred species of mushrooms growing throughout the world. virtually nonexistent – there remains no conclusive Many of these species also grow in parts of the United States, evidence of any fatalities despite ingestion particularly in the Deep South and the Pacific Northwest. Psilocybin (often accidental) of dosages greatly exceeding the mushrooms have a long history of ritualistic use by the native effective amount. No apparent physiological populations of Mesoamerica; the Aztecs called them teonanacatl damage from the use of psilocybin has been (“flesh of the gods”). Contemporary users of mushrooms containing observed from the limited research conducted to psilocybin will experience LSD-like effects, although of considerably date (Grinspoon and Bakalar 1997; Stamets 1916). shorter duration. Of particular concern for mushroom foragers SLANG however, is the risk of poisoning resulting from misidentification. It is estimated that toxic Magic mushrooms, shrooms, mushies, cubes (for psilocybe cubensis), mushroom species outnumber those containing liberty caps (for psilocybe semilanceata). psilocybin by at least ten to one. Many mushroom hunters do not realize that there are some extremely poisonous species, which superficially resemble AVAILABILITY & USE particular mushrooms containing psilocybin (Stamets 1996). The number of mushroom species growing wild in the United States and found to contain psilocybin continues to increase. In the Pacific As with LSD, the actual risks posed by psilocybin Northwest alone, over a dozen species of such mushrooms have are predominantly psychological in nature. -
Dosing Creativity
UvA-DARE (Digital Academic Repository) Drug-craft On the configurations of psychedelic efficacies Mishra, S. Publication date 2020 Document Version Other version License Other Link to publication Citation for published version (APA): Mishra, S. (2020). Drug-craft: On the configurations of psychedelic efficacies. General rights It is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), other than for strictly personal, individual use, unless the work is under an open content license (like Creative Commons). Disclaimer/Complaints regulations If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library: https://uba.uva.nl/en/contact, or a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible. UvA-DARE is a service provided by the library of the University of Amsterdam (https://dare.uva.nl) Download date:06 Oct 2021 Chapter 1 Dosing Creativity Besides alcohol, I don’t really use drugs and have little interest in them, but this microdosing – for work, being creative, for being focused and effective… its increased use by Silicon Valley professionals – it did catch my attention. You research drugs, what do you think about it? I would like to try it someday. (Informal conversation, Amsterdam 2017) This is what Jan said to me, on an afternoon at my research institute in Amsterdam, as we bumped into each other by the department’s coffee machine. -
The Effect of Microdosing Classical Psychedelics on Cognitive Performance
University of Central Florida STARS Honors Undergraduate Theses UCF Theses and Dissertations 2021 The Effect of Microdosing Classical Psychedelics On Cognitive Performance Michael Harris University of Central Florida Part of the Chemicals and Drugs Commons, and the Psychology Commons Find similar works at: https://stars.library.ucf.edu/honorstheses University of Central Florida Libraries http://library.ucf.edu This Open Access is brought to you for free and open access by the UCF Theses and Dissertations at STARS. It has been accepted for inclusion in Honors Undergraduate Theses by an authorized administrator of STARS. For more information, please contact [email protected]. Recommended Citation Harris, Michael, "The Effect of Microdosing Classical Psychedelics On Cognitive Performance" (2021). Honors Undergraduate Theses. 974. https://stars.library.ucf.edu/honorstheses/974 THE EFFECT OF MICRODOSING CLASSICAL PSYCHEDELICS ON COGNITIVE PERFORMANCE by MICHAEL HARRIS A thesis submitted in partial fulfillment of the requirements for the Honors in the Major Program in Psychology in the College of Sciences and in the Burnett Honors College at the University of Central Florida Orlando, Florida Spring Term, 2021 Thesis Chair: Daniel McConnell, PhD ABSTRACT Public interest and scientific inquiry are currently bringing psychedelic research back into the spotlight after a decades-long respite from clinical human trials. A majority of the research during this recent renaissance has surrounded applications of psychedelics in the fields of mental health. Less attention is being focused to other research areas where psychedelics may also prove informative, such as cognition and information processing. A common trend taking place is the act of administering very small doses of psychedelics as a potential cognitive enhancer, called microdosing. -
Aspects Op Secondary Metabolism in Basidiqmycetes
ASPECTS OP SECONDARY METABOLISM IN BASIDIQMYCETES BIOLOGICAL AND BIOCHEMICAL STUDIES ON PSILOCYBE CUBENSIS A SURVEY OF PHENOL-O-METHYLTRANSFERASE IN SPECIES OF LENTINUS AND LENTINELLUS by by.' . WEI-WEI/WANG B.Sc, National Taiwan University, 1974 A THESIS SUBMITTED IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE DEGREE OF MASTER OF SCIENCE in THE FACULTY OF GRADUATE STUDIES (DEPARTMENT OF BOTANY) We accept 'this thesis as conforming to the required standard THE UNIVERSITY OF BRITISH COLUMBIA November, 1977 f7\ Wei-Wei Wang, 1977 In presenting this thesis in partial fulfilment of the requirements for an advanced degree at the University of British Columbia, I agree that the Library shall make it freely available for reference and study. I further agree that permission for extensive copying of this thesis for scholarly purposes may be granted by the Head of my Department or by his representatives. It is understood that copying or publication of this thesis for financial gain shall not be allowed without my written permission. Department of Botany The University of British Columbia 2075 Wesbrook Place Vancouver, Canada V6T 1W5 Date December 6. 1977 ii ABSTRACT I. Psilocybe cubensis was cultured successfully in two media. Medium A was devised by Catalfomo and Tyler and Medium B was a modification of a medium which has been used for ergot alkaloid production by Claviceps purpurea. Only when the fungus was kept on Sabouraud agar plates.did it subsequently produce psilocybin when transferred to liquid media. A quantitative time-course study of psilocybin production in the two media was carried out. Maximal production appeared on the fifth day. -
Ihe Jbialwogeiii Law Heporterjj Chicago Police Seize
Ihe JbialWogeiii Law HeporterJJ Issue No. 9 ISSN 1074-8040 Winter 1995 Chicago Police Seize 10,000 Doses Conceptual Artwork GALLERY DIRECTOR ARRESTED AND ARREST WARRANT ISSUED FOR ARTIST of the Chicago Police Department entered Chicago'sFeigen, Inc., art gallery On Augustand 10,1995,seized an membersartwork title ofthed W.O OrganizedOODoses. TCrimehepie candewa sNarcoticscreatedby Gdivisionregory [The seizure oj10,000 Green a 36-year-old artist with a masters of fine arts degree from the School of Art Doses was] Institute of Chicago. Created in 1994,10,000 Doses was a mixed-media sculpture consisting of 12 quart-sized laboratory bottles filled with an amber-colored liquid. frightening because The bottles were arranged in rows on a small industrial metal table. At the time of its confiscation, 10,000 Doses was in the front window ofthe Feigen gallery, and on the Chicago Police the window was emblazoned a four-foot-high revised recipe for making LSD in the had a knee-jerk kitchen, taken from The Anarchist Cookbook. Four days after seizing the work, the Chicago Police Department informed the reaction that this gallery that drug-testing of the liquid inside the bottles was "positive." Arrest artist violated the law. warrants were issued for artist Gregory Green as well as Lance Kiiiz, the gallery co- director. Mr. Green, who lives in New York, was not arrested, but Mr. Kinz, who They should have lives in Chicago, was taken into custody and charged with felony possession ofLSD. Chicago Police issued statements estimating that the roughly three gallons of liquid carefully analyzed the could have supplied 230,000 doses ofLSD with an alleged "street value" of $1.2 [presumed] controlled million dollars.