Magic™ Anti-GPHN (Aa 500-600) Polyclonal Antibody (DPABH-26837) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Magic™ Anti-GPHN (aa 500-600) polyclonal antibody (DPABH-26837) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules (By similarity). Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.

Immunogen Synthetic peptide conjugated to KLH derived from within residues 500 - 600 of Human Gephyrin.

Isotype IgY

Source/Host Chicken

Species Reactivity Mouse, Rat, Human

Purification Immunogen affinity purified

Conjugate Unconjugated

Applications IHC-P, ICC/IF

Format Liquid

Size 100 μg

Buffer pH: 7.40; Constituents: PBS, 3% BSA

Preservative 0.02% Sodium Azide

Storage Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or - 80°C. Avoid freeze / thaw cycle.

GENE INFORMATION

Gene Name GPHN gephyrin [ Homo sapiens ]

Official Symbol GPHN

Synonyms GPHN; gephyrin; GPH; GEPH; HKPX1; GPHRYN; MOCODC;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Protein Refseq NP_001019389.1

UniProt ID Q9NQX3

Pathway Defective AMN causes hereditary megaloblastic anemia 1; Defective CD320 causes methylmalonic aciduria; Defective GIF causes intrinsic factor deficiency; Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF

Function ATP binding; metal ion binding; molybdopterin adenylyltransferase activity; molybdopterin molybdotransferase activity

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]