Magic™ Anti-GPHN (aa 500-600) polyclonal antibody (DPABH-26837) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Antigen Description Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules (By similarity). Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. Immunogen Synthetic peptide conjugated to KLH derived from within residues 500 - 600 of Human Gephyrin. Isotype IgY Source/Host Chicken Species Reactivity Mouse, Rat, Human Purification Immunogen affinity purified Conjugate Unconjugated Applications IHC-P, ICC/IF Format Liquid Size 100 μg Buffer pH: 7.40; Constituents: PBS, 3% BSA Preservative 0.02% Sodium Azide Storage Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or - 80°C. Avoid freeze / thaw cycle. GENE INFORMATION Gene Name GPHN gephyrin [ Homo sapiens ] Official Symbol GPHN Synonyms GPHN; gephyrin; GPH; GEPH; HKPX1; GPHRYN; MOCODC; 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Entrez Gene ID 10243 Protein Refseq NP_001019389.1 UniProt ID Q9NQX3 Pathway Defective AMN causes hereditary megaloblastic anemia 1; Defective CD320 causes methylmalonic aciduria; Defective GIF causes intrinsic factor deficiency; Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Function ATP binding; metal ion binding; molybdopterin adenylyltransferase activity; molybdopterin molybdotransferase activity 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved.
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