Course Title/Code: Functional Neuroimaging- Phys 4710/6710/Neuro 6330 Course Credit: 3 Meeting times/place: TR 11:00 AM – 12:15 PM / Classroom South 528

Course Objectives

Neuroimaging is a rapidly developing multidisciplinary field with new possibilities of understanding the brain both in health and disease. Functional neuroimaging tools, such as fMRI and EEG, aim to provide valuable insights into brain structure-function and brain-behavior relationships. This course is suitable for students with an interest in using neuroimaging tools. The objective of this course is to help students understand (i) the principles, potential and limitations of brain imaging techniques, (ii) the relationship of neurophysiology and brain imaging data (iii) the experimental design principles and basic data analysis methods, and (iv) how brain imaging techniques are applied to answer questions in cognitive neuroscience.

Course materials

• Functional Magnetic Resonance Imaging by Huettel, Song, and McCarthy • Articles from Scholarpedia and Other scientific Journals (Available from Pubmed /GSU subscription)

Instructor Dr. Mukesh Dhamala Office: Science Annex, Room #456 Phone: (404) 413-6043 Email: [email protected] Web: http://www.phy-astr.gsu.edu/dhamala/dhamala.html Office hours: Tuesday afternoon, or by appointment

Grading Final Grade= 40%(Homework)+30%(Class Quiz)+30%(Final Project/Presentation) Letter Grades: A= 4.0, A-, B+, B= 3.0, B-, C+, C=2.0, C-, D=1.0, F =0.0 (x+/- =x +/-0.33) Grade scale: > 90 (A), > 80 (B), >70 (C), >60 (D), <60 (F)

Final Project Presentation December 12, 2013 (10:45AM to 1:15AM)

Disability Services Students who wish to request accommodation for a disability may do so by registering with the Office of Disability Services of a signed Accommodation Plan and are responsible for providing a copy of that plan to instructors of all classes in which an accommodation is sought.

Honor code It is the responsibility of the students to abide by the GSU academic honesty policy .

Course evaluation Constructive assessment of this course from students plays an indispensable role in shaping education at Georgia State University. Upon completing the course, students are requested to fill out the online course evaluation.

Lectures

• Week 1 : Introduction to Functional Neuroimaging, Basic Physics Review • Week 2 : NeuroPhysics of EEG Assignment 1 • Week 3 : MRI Physics and Image Formation • Week 4 : MR Contrast Mechanisms, Pulse Sequences, Hands- on experience with a ‘little’ MR system Assignment 2 • Week 5 : From Neuronal to Hemodynamic Activity • Week 6 : Physics of BOLD fMRI Assignment 3, Quiz 1 • Week 7 : Simultaneous EEG-fMRI • Week 8 : Preprocessing of fMRI data Assignment 4 • Week 9 : Experimental Design • Week 10 : Analysis of fMRI data • Week 11 : Preprocessing and analysis of EEG data Assignment 5 • Week 12 : Application I: fMRI study (brain node and network activity) • Week 13 : Application II: EEG study (brain node and network activity) Assignment 6, Quiz 2 • Week 14 : MRI/fMRI data analysis tools and demo Final Projects + Presentations : Brain Connectivity, EEG forward and inverse solutions, DTI, VBM, Resting-State Brain Networks, Brain Analysis Tools: PCA/ICA, …

Holidays: Sept 2 (Labor day), Thanksgiving Break (Nov 25 – 30)

Here is the link to GSU academic calendar for the fall of 2013: http://registrar.gsu.edu/files/2013/05/Academic_Year_2013-2014.pdf