N o i s e C The book offers noise technologies for monitoring of the beginning of o n cardiovascular and respiratory diseases, considering the possibility of t r listening to the sounds of heart and lungs by means of mobile phones. o l Such estimates of the sounds of heart and lungs as noise variance, value of o f noise correlation, cross-correlation function between the useful signal and H the noise and coefficient of correlation are used as informative attributes e a for identification of the beginning of the latent period of diseases. For this r t purpose, obtained noise estimates are taken as symptoms and, by training, their combinations are used to form the set of reference symptoms and the bank of set of symptoms of both disease state and healthy state of the phone user, who after a certain training period can use the phone as a device for noise control of his heart and lungs health. Duplication of monitoring with application of informative attributes obtained by means of technologies for robust correlation, spectral and position-binary analysis provides validity of results. Telman Aliev Tahir Alizada Narmin Rzayeva Telman Aliev Telman Aliev was born in 1935 in Azerbaijan. 1977 – Noise Control of Heart by Doctor of Computing Sciences, 1985 – Professor, 1991 – Keldysh Medal, 2001 – full member of the Azerbaijan National Academy of Sciences, 2004 – Means of a Mobile Phone Order of Glory AR. Director of Cybernetics Institute (Baku) since 1988. Telman Aliev is author of over 400 Noise analysis of the sound of heart and published papers, 60 patents and 10 monographs. lungs for monitoring of the beginning of the latent period of their diseases A l i e v , A l i z a d a , R z a y e 978-3-659-31130-7 v a Contents Preface ........................................................................................................................... 9 Introduction ................................................................................................................. 19 Chapter 1. Applicability of mobile phones for noise control of heart performance ............................................................................................................... 27 1.1 Mission of computer diagnostics of cardiovascular and respiratory systems...................................................................................................................... 27 1.2 Purposes of noise monitoring in noise control of the heart on a mobile phone......................................................................................................................... 29 1.3 Complications of use of mobile phones in noise control of the heart with application of conventional technologies ................................................................. 31 1.4 Factors influencing the adequacy of process of control of the heart by correlation analysis methods..................................................................................... 32 1.5 Factors influencing the adequacy of computer diagnostics by spectral analysis methods....................................................................................................... 36 1.6 Influence of filtration on the adequacy of computer diagnostics ....................... 38 1.7 Influence of conventional methods of choice of sampling interval on the adequacy of computer diagnostics............................................................................ 40 Chapter 2. Robust technology for correlation noise analysis of heart sound and sound of human respiratory organs...................................................... 43 2.1 Specifics of analysis of heart sound and sound of respiratory organs with application of correlation analysis technology ......................................................... 43 2.2 Technology for calculation of the value providing robustness of estimates of auto- and cross-correlation functions of heart sound and sound of respiratory organs........................................................................................................................ 44 5 Contents 2.3 Robust algorithms for improving estimates of correlation functions of the sound of heart and respiratory organs....................................................................... 49 2.4 Digital technology for analysis of noise and useful signal of heart sound and sound of respiratory organs in the absence of correlation between them.......... 52 2.5 Digital technology for calculation of noise variance of heart sound and sound of respiratory organs in the presence of correlation between the useful signal and the noise................................................................................................... 55 2.6 Correlation technologies for noise indication of the beginning of origin of cardiovascular diseases............................................................................................. 61 2.7 Robust noise technology of monitoring of the beginning of origin of cardiovascular diseases............................................................................................. 64 2.8 Technology of determination of estimates of cross-correlation function and coefficient of correlation between the useful signal and the noise of heart sound and sound of respiratory organs ..................................................................... 67 2.9 Robust correlation indicators of the beginning of origin of cardiovascular diseases ..................................................................................................................... 70 Chapter 3. Robust technology for spectral noise analysis of heart sound and sound of human respiratory organs ........................................................................ 73 3.1 Spectral robust technology for analysis of heart and lungs sound ..................... 73 3.2 Origin of difference of positive and negative errors from noise in spectral analysis of heart and lungs sound received at the output of a mobile phone microphone ........................................................................................ 76 3.3 Algorithms for determination of robust estimates of Fourier series coefficients in spectral monitoring of the condition of heart and lungs................... 81 3.4 Robust spectral indicators of origin of cardiovascular diseases......................... 87 Chapter 4. Position-binary technology for noise analysis of periodic sound of human heart and respiratory organs .................................................................. 93 4.1 Specific character of heart and lungs sound received at the output of microphones of mobile phones................................................................................. 93 6 Contents 4.2 Position-binary technology for analysis of heart and lungs sound received from microphones of mobile phones ........................................................................ 94 4.3 Possibility of application of position-binary technology for monitoring of the condition of cardiovascular and respiratory systems.......................................... 98 4.4 Excessive frequency sampling of signals of heart and respiratory organs......... 99 4.5 Position-binary noise analysis of the sound of heart and respiratory organs ... 104 4.6 Position-binary indicators of the beginning of origin of cardiovascular and respiratory diseases................................................................................................. 108 Chapter 5. Forms of noise monitoring of the latent period of deviation of condition of heart and respiratory organs from the norm by mobile phones ....................................................................................................................... 111 5.1 Correlation robust technology for monitoring of the beginning of the latent period of vascular pathology of human body ............................................... 111 5.2 Forms of noise monitoring and control of the latent period of deviation of cardiovascular and respiratory systems from the norm by mobile phones ............ 116 References ................................................................................................................. 131 Appendix A: Multichannel voltage-to-digital converter (Author's certificate) ........ 141 Appendix B: Multichannel correlation meter (Author's certificate) ......................... 142 Appendix C: Multichannel correlator (Author's certificate)..................................... 143 Appendix D: Multichannel adaptive device for transmission of information with delta modulation (Author's certificate)........................................ 144 Appendix E: Device for illness diagnostics (Author's certificate)............................ 145 Appendix F: Multifunctional analog-to-digital converter (Author's certificate) ...... 146 Appendix G: Stationary stochastic objects diagnostics device (Author's certificate)............................................................................................ 147 Appendix H: Device for information registration (Author's certificate) .................. 148 Appendix I: Signals receiving and transmission device (Author's certificate)......... 149 7 Contents Appendix J: Analyzer of rheovasosignals for indication of existence of permeability-breach vessels (Author's certificate) ............................... 150 Appendix K: Expert system (Eurasian patent).......................................................... 151 Appendix L: Method of monitoring of the