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CURRICULUM VITAE 1. Personal Details Family name, first name: Purim Ofer Date & place of birth: February 10, 1970, Israel Address (Office): Department of Oncology, Assuta Academic Hospital, Ashdod 7747629, Israel (Residence): 6 Wengrover Street, Petach Tikva, Israel Telephone number (Office): +972-72-3398127 (Residence): +972-77-2002848 Cellular phone number: +972-52-4841199 Fax number: +972-72-3399087 E-mail address: [email protected] 2. Academic Education 1992-1995 Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel Subject: Life Sciences BSc degree 1996-1998 School of Dentistry, Tel Aviv University, Tel Aviv, Israel 1998-2002 University of Szeged, Szeged, Hungary Subject: Medicine MD degree [Cum Laude] Title of Doctoral Dissertation: Identification of sentinel node with gamma probe with technetium in melanoma patients 3. Professional Training 2003 Internship, Rabin Medical Center – Beilinson Hospital, Petach Tikva, Israel 2004-2010 Resident in Institute of Oncology, Rabin Medical Center – Beilinson Hospital, Petach Tikva, Israel 2008 GCP course, Shefayim, Israel 3. Professional Training 2010-2017 Attending Physician, Institute of Oncology, Davidoff Cancer Center, Rabin Medical Center – Beilinson Hospital, Petach Tikva, Israel Since 11/17 Head of Gastrointestinal Malignancy Service, Assuta Academic Hospital, Ashdod, Israel 4. Board Certification Passed Oncology Step A 2007 Passed Oncology Step B 2009 Oncology Specialty 2009 5. Professional Licensing Medical License #37134 2002 Specialty License #28470 2009 6. Employment History Year Position Department Institution 2003 Internship Rabin Medical Center – Beilinson Hospital, Petach Tikva, Israel 2004-2010 Resident Institute of Oncology Rabin Medical Center – Beilinson Hospital, Petach Tikva, Israel 2010-2017 Attending Institute of Oncology Rabin Medical Center – Physician Beilinson Hospital, Petach Tikva, Israel Since Nov 2017 Head Gastrointestinal Assuta Academic Hospital, Malignancy Service Ashdod, Israel 7. Academic Appointments Year Title (Rank) Department Faculty University 2006 Tutor Oncology Sackler Tel Aviv University 9. Membership in Professional/Scientific Societies Year Name of Society 2004 Israel Medical Association 2005 Israel Society of Clinical Oncology and Radiotherapy 2010 American Society of Clinical Oncology 11. Additional Functions (Committee memberships, academic and administrative functions) Year Function Since 2008 Gave Frontal Lectures to Family Physicians, Nurses, Oncological Residents, Pharmacists 13. Scientific Publications Hindex h-index 6 Sum of Times Cited 252 Without self citations 247 Refereed articles in scientific journals 1. Articles Published 1. Kundel Y*, Purim O*, Figer A, Stemmer SM, Tichler T, Sulkes J, Sulkes A, Brenner B. (*Equal Contribution) Weekly infusional high-dose 5-fluorouracil and leucovorin and biweekly cisplatin: a convenient treatment option in advanced gastric cancer. Med Sci Monit. 2008 Apr;14(4):CR190-5. (MEDICINE, RESEARCH & EXPERIMENTAL JR 89/128, Q3, IF 1.585, CI 1) 2. Joachims Z, Feinmesser R, Purim O, Halpern M, Brenner B, Fenig E, Roizman P, Sulkes J, Feinmesser M. Cyclooxygenase-2 expression in primary and metastatic Merkel cell carcinoma. Appl Immunohistochem Mol Morphol. 2008 Oct;16(5):442-6. (ANATOMY & MORPHOLOGY JR 8/21, Q2, IF 1.634, CI 4) 3. Kundel Y, Brenner R, Purim O, Peled N, Idelevich E, Fenig E, Sulkes A, Brenner B. Is local excision after complete pathological response to neoadjuvant chemoradiation for rectal cancer an acceptable treatment option? Dis Colon Rectum. 2010 Dec;53(12):1624-31. (SURGERY JR 32/197, Q1, IF 3.519, CI 43) 4. Brenner B*, Hoshen MB*, Purim O*, David MB, Ashkenazi K, Marshak G, Kundel Y, Brenner R, Morgenstern S, Halpern M, Rosenfeld N, Chajut A, Niv Y, Kushnir M. (*Equal Contribution) MicroRNAs as a potential prognostic factor in gastric cancer. World J Gastroenterol. 2011 Sep 21;17(35):3976-85. (GASTROENTEROLOGY & HEPATOLOGY JR 30/79, Q2, IF 3.365, CI 76) 5. Kundel Y*, Purim O*, Idelevich E, Lavrenkov K, Man S, Kovel S, Karminsky N, Pfeffer RM, Nisenbaum B, Fenig E, Sulkes A, Brenner B. (*Equal Contribution) Postoperative chemoradiation for resected gastric cancer--is the Macdonald Regimen Tolerable? A retrospective multi-institutional study. Radiat Oncol. 2011 Sep 29;6:127. (RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING JR 38/127, Q2, IF 2.568, CI 9) 6. Dreznik A, Purim O, Idelevich E, Kundel Y, Sulkes J, Sulkes A, Brenner B. Gastric cancer: biology and clinical manifestations in Israel. J Surg Oncol. 2012 Mar;105(3):316-22. (SURGERY JR 43/197, Q1, IF 2.993, CI 3) 1. Articles Published 7. Ben Aharon I*, Purim O*, Kundel Y, Brenner R, Gordon N, Sulkes A, Brenner B. (*Equal Contribution) The combination of docetaxel, cisplatin, and 5-fluorouracil in advanced gastric cancer: a single-institution experience. Anticancer Drugs. 2012 Mar;23(3):313-20. (PHARMACOLOGY & PHARMACY JR 135/257, Q3, IF 2.320, CI 5) 8. Rath-Wolfson L, Purim O, Ram E, Morgenstern S, Koren R, Brenner B. Expression of estrogen receptor β1 in colorectal cancer: correlation with clinicopathological variables. Oncol Rep. 2012 Jun;27(6):2017-22. (ONCOLOGY JR 125/217, Q3, IF 2.662, CI 5) 9. Weissmann-Brenner A, Kushnir M, Lithwick Yanai G, Aharonov R, Gibori H, Purim O, Kundel Y, Morgenstern S, Halperin M, Niv Y, Brenner B. Tumor microRNA-29a expression and the risk of recurrence in stage II colon cancer. Int J Oncol. 2012 Jun;40(6):2097-103. (ONCOLOGY JR 105/217, Q2, IF 3.079, CI 39) 10. Goldberg N*, Kundel Y*, Purim O*, Bernstine H, Gordon N, Morgenstern S, Idelevich E, Wasserberg N, Sulkes A, Groshar D, Brenner B. (*Equal Contribution) Early prediction of histopathological response of rectal tumors after one week of preoperative radiochemotherapy using 18 F-FDG PET-CT imaging. A prospective clinical study. Radiat Oncol. 2012 Aug 1;7:124. (RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING JR 38/127, Q2, IF 2.568, CI 19) 11. Purim O, Gordon N, Brenner B. Cancer of the colon and rectum: potential effects of sex-age interactions on incidence and outcome. Med Sci Monit. 2013 Mar 20;19:203-9. (MEDICINE, RESEARCH & EXPERIMENTAL JR 89/128, Q3, IF 1.585, CI 20) 12. Purim O*, Kundel Y*, Shapira R, Tichler T, Brenner B. (*Equal Contribution) Dose-Dense Regimen of Cisplatin and Infusional Fluorouracil in Advanced Gastric Cancer: A Single Institution Experience. J Cancer Therapy. 2013 Apr;4(2):529-35. (No IF, CI ) 1. Articles Published 13. Kundel Y, Nasser NJ, Purim O, Yerushalmi R, Fenig E, Pfeffer RM, Stemmer SM, Rizel S, Symon Z, Kaufman B, Sulkes A, Brenner B. Phase II Study of Concurrent Capecitabine and External Beam Radiotherapy for Pain Control of Bone Metastases of Breast Cancer Origin. PLoS One. 2013 Jul 10;8(7):e68327. (MULTIDISCIPLINARY SCIENCES JR 15/64, Q1, IF 2.806, CI 1) 14. Brenner RM, Kivity S, Kundel Y, Purim O, Peled N, Idelevich E, Lavrenkov K, Kovel S, Fenig E, Sulkes A, Brenner B. Ethnic variation in toxicity and outcome of adjuvant chemoradiation for gastric cancer in Israel. Anticancer Res. 2013 Nov;33(11):5151-7. (ONCOLOGY JR 161/217, Q3, IF 1.937, CI 0) 15. Dickman R, Kundel Y, Levy-Drummer R, Purim O, Wasserberg N, Fenig E, Sulkes A, Brenner B. Restaging locally advanced rectal cancer by different imaging modalities after preoperative chemoradiation: a comparative study. Radiat Oncol. 2013 Nov 29;8:278. (RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING JR 38/127, Q2, IF 2.568, CI 4) 16. Berger Y, Zbar AP, Lebedyev A, Levi Y, Nevler A, Aderka D, Golan T, Purim O, Brenner B, Natur M, Gutman M. [Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis of colorectal and appendiceal origin]. Harefuah. 2014 Jun;153(6):315-9, 368. (No IF, CI ) 17. Vilkin A, Halpern M, Morgenstern S, Brazovski E, Gingold-Belfer R, Boltin D, Purim O, Kundel Y, Welinsky S, Brenner B, Niv Y, Levi Z. How reliable is immunohistochemical staining for DNA mismatch repair proteins performed after neoadjuvant chemoradiation? Hum Pathol. 2014 Oct;45(10):2029-36. (PATHOLOGY JR 18/79, Q1, IF 3.014, CI 5) 18. Wasserberg N, Kundel Y, Purim O, Keidar A, Kashtan H, Sadot E, Fenig E, Brenner B. Sphincter preservation in distal CT2N0 rectal cancer after preoperative chemoradiotherapy. Radiat Oncol. 2014 Oct 22;9:233. (RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING JR 38/127, Q2, IF 2.568, CI 1) 1. Articles Published 19. Epelbaum R, Shacham-Shmueli E, Klein B, Agbarya A, Brenner B, Brenner R, Gez E, Golan T, Hubert A, Purim O, Temper M, Tepper E, Voss A, Russell K, Dvir A, Soussan-Gutman L, Stemmer SM, Geva R. Molecular Profiling-Selected Therapy for Treatment of Advanced Pancreaticobiliary Cancer: A Retrospective Multicenter Study. Biomed Res Int. 2015;2015:681653. (BIOTECHNOLOGY & APPLIED MICROBIOLOGY JR 67/160, Q2, IF 2.476, CI 1) 20. Wasserberg N*, Purim O*, Bard V, Kundel Y, Gordon N, Groshar D, Goldberg N, Kashtan H, Sulkes A, Brenner B. (*Equal Contribution) Early postoperative 18F-FDG PET/CT in high-risk stage III colorectal cancer. Clin Nucl Med. 2015 Apr;40(4):e222-7. (RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING JR 12/127, Q1, IF 4.563, CI 3) 21. Levi M, Shalgi R, Brenner B, Perl G, Purim O, Amit L, Stemmer SM, Ben- Aharon I. The impact of oxaliplatin on the gonads: from bedside to the bench. Mol Hum Reprod. 2015 Dec;21(12):885-93. (OBSTETRICS & GYNECOLOGY JR 10/80, Q1, IF 3.585, CI 2) 22. Brenner B, Geva R, Rothney M, Beny A, Dror Y, Steiner M, Hubert A, Idelevich E, Gluzman A, Purim O, Shacham-Shmueli E, Shulman K, Mishaeli M, Man S, Soussan-Gutman L, Tezcan H, Chao C, Shani A, Liebermann N. Impact of the 12-Gene Colon Cancer Assay on Clinical Decision Making for Adjuvant Therapy in Stage II Colon Cancer Patients. Value Health. 2016 Jan;19(1):82-7. (HEALTH CARE SCIENCES & SERVICES JR 10/90, Q1, IF 4.235, CI 2) 23.