Anti-NOX5 (Internal Region) Polyclonal Antibody (DPAB-DC3268) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-NOX5 (internal region) polyclonal antibody (DPAB-DC3268) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description This gene is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes. It encodes a calcium-dependen NADPH oxidase that generates superoxide, and functions as a calcium-dependent proton channel that may regulate redox-dependent processes in lymphocytes and spermatozoa. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Specificity This antibody is expected to recognize all reported isoforms (NP_078781.3; NP_001171708.1; NP_001171709.1).

Immunogen A synthetic peptide corresponding to amino acids at internal region of human NOX5. The sequence is C-EWHPFTISSAPEQKD

Source/Host Goat

Species Reactivity Human

Purification Antigen affinity purification

Conjugate Unconjugated

Applications WB (Tissue lysate), ELISA,

Format Liquid

Concentration 0.5 mg/mL

Size 100 μg

Buffer In 0.5 mg/mL in Tris saline, pH7.3 (0.5% BSA, 0.02% sodium azide)

Preservative 0.02% Sodium Azide

Storage Store at -20°C.Aliquot to avoid repeated freezing and thawing.

GENE INFORMATION

Gene Name NOX5 NADPH oxidase, EF-hand calcium binding domain 5 [ Homo sapiens (human) ]

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Synonyms NOX5; NADPH oxidase, EF-hand calcium binding domain 5; NADPH oxidase 5;

Entrez Gene ID 79400

Protein Refseq NP_001171708

UniProt ID A3QRJ0

Chromosome Location 15q23

Function NADP binding; calcium ion binding; flavin adenine dinucleotide binding; heme binding

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]