Anti-NOX5 (internal region) polyclonal antibody (DPAB-DC3268) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Antigen Description This gene is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes. It encodes a calcium-dependen NADPH oxidase that generates superoxide, and functions as a calcium-dependent proton channel that may regulate redox-dependent processes in lymphocytes and spermatozoa. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. Specificity This antibody is expected to recognize all reported isoforms (NP_078781.3; NP_001171708.1; NP_001171709.1). Immunogen A synthetic peptide corresponding to amino acids at internal region of human NOX5. The sequence is C-EWHPFTISSAPEQKD Source/Host Goat Species Reactivity Human Purification Antigen affinity purification Conjugate Unconjugated Applications WB (Tissue lysate), ELISA, Format Liquid Concentration 0.5 mg/mL Size 100 μg Buffer In 0.5 mg/mL in Tris saline, pH7.3 (0.5% BSA, 0.02% sodium azide) Preservative 0.02% Sodium Azide Storage Store at -20°C.Aliquot to avoid repeated freezing and thawing. GENE INFORMATION Gene Name NOX5 NADPH oxidase, EF-hand calcium binding domain 5 [ Homo sapiens (human) ] 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Official Symbol NOX5 Synonyms NOX5; NADPH oxidase, EF-hand calcium binding domain 5; NADPH oxidase 5; Entrez Gene ID 79400 Protein Refseq NP_001171708 UniProt ID A3QRJ0 Chromosome Location 15q23 Function NADP binding; calcium ion binding; flavin adenine dinucleotide binding; heme binding 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved.