2004 Eastern Society for Pediatric Research 16Th Annual Meeting
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2004 Eastern Society for Pediatric Research 16th Annual Meeting Program Guide March 26–28, 2004 Hyatt Regency Old Greenwich, CT In cooperation with the New York Academy of Medicine New for 2004 We are pleased to announce that we have engaged the services of the New York Academy of Medicine (NYAM) to run our 2004 meeting. They will also sponsor the CME program. While our recent meetings have been terrific, the administrative burden has exceeded what could reasonably be expected of our volunteers. We expect the engagement of the professional meeting planners at the NYAM will further enhance our meeting. This will include improved informatics enabling presenters to load their PowerPoint presentations at a central station in advance, avoiding some of the glitches we encountered last year. ESPR Officers and Council Sponsorship Honor Roll 2003–2004 President The ESPR expresses its appreciation to all of our Luc P. Brion, M.D. sponsors of the 2004 ESPR Annual Meeting Albert Einstein College of Medicine and Children’s Hospital at Montefiore, Established Sponsors Bronx, New York Curative Pharmacy Services Mead-Johnson Nutritionals Secretary-Treasurer Rashmin C. Savani, M.B.Ch.B. MedImmune, Inc. The University of Pennsylvania School of Medicine, Philips Medical Systems Philadelphia, Pennsylvania Ross Products Division of Abbott Laboratories, Inc. Chairperson, Planning Committee Additional Sponsors Bruce D. Gelb, M.D. Mount Sinai School of Medicine Dey L. P. New York, New York INO Therapeutics, Inc. Council Members Immediate Past President Mercury Medical Anthony Alario, MD Viasys Healthcare Mitchell J. Kresch, MD Clifford Bogue, MD Bruce D. Gelb, MD Academic Sponsors Ian Holzman, MD Past Presidents Alan R. Cohen, MD Philip Larussa, MD The Children’s Hospital of Philiadelphia Lawrence M. Nogee, MD Laurence Finberg, MD Philadelphia, Pennsylvania Joseph B. Warshaw, MD Planning Committee Gabriel Haddad, MD Bruce D. Gelb, MD (Chair) Marc Yudkoff, MD Children’s Hospital at Montefiore, Bronx, New York Clifford W. Bogue, MD Alan R. Fleischman, MD Luc P. Brion, MD Margaret K. Hostetter, MD Heber Nielsen, MD Ira H. Gewolb, MD Yale University, New Haven, Connecticut Lawrence M. Nogee, MD Thomas R. Welch, MD Daniel Notterman, MD SUNY Upstate Medical University, Syracuse, New York CONTENTS Faculty . 1 Meeting Services and CME Accreditation . 2 Schedule-at-a-Glance . 3 Friday Programming . 4 Saturday Programming . 5 Sunday Programming . 10 Abstracts . 12 Author Index . 46 Hyatt Regency Facilities Map . Inside Back Cover Welcome to the 16th Annual Meeting! Dear Colleagues: Welcome to the 16th Annual Meeting of the Eastern Society for Pediatric Research (ESPR)! We are sure that this will be an exciting meeting with excellent State-of-the-Art Plenary Talks, a Lunch with the Professors Educational Program, featured speakers at subspecialty sessions and a large number of high-quality abstracts. The organization of this meeting would not have been possible without the help of the American Pediatric Society and the Society for Pediatric Research, especially Deborah Atwood, Information Services Director of the APS/SPR, and Debbie Anagnostelis, APS/SPR Executive Director, as well as Marathon Multimedia. We would like to acknowledge the ESPR Planning Committee and the other members of the ESPR Council for their help. We appreciate the meeting planning and provision of CME accreditation by the New York Academy of Medicine Office of Continuing Medical Education, especially Donald Morcone. We would like to thank our corporate and academic sponsors who were instrumental in making this meeting possible. We are confident that this meeting continues to satisfy the mission of the ESPR in providing a forum for young investigators to present their research in a structured, yet informal and relaxed atmosphere, and by offering timely educational programs that address important current clinical and basic science questions in Pediatrics. Thank you for attending! We look forward to sharing this time with you. Luc P. Brion, MD Rashmin C. Savani, MB, ChB Bruce D. Gelb, MD President Secretary-Treasurer Chair, Planning Committee Faculty Michael F. Artman, MD Stephen Ludwig, MD Michael Rosenbaum, MD New York University The Children’s Hospital of Philadelphia Columbia University College of School of Medicine Philadelphia, Pennsylvania Physicians and Surgeons New York, New York New York, New York Laura R. Ment, MD Diane Bianchi, MD Yale University School of Medicine Karen Santucci, MD Tufts-New England Medical Center and New Haven, Connecticut Yale University and New Haven Tufts University School of Medicine Children’s Hospital Ed Morrisey, PhD Boston, Massachusetts University of Pennsylvania New Haven, Connecticut Luc P. Brion, MD School of Medicine Rashmin Savani, MBChB Albert Einstein College of Medicine and Philadelphia, Pennsylvania University of Pennsylvania Children’s Hospital at Montefiore School of Medicine Bronx, New York Heber Nielsen, MD Tufts-New England Medical Center and Philadelphia, Pennsylvania William Carroll, MD Tufts University School of Medicine Tor Savidge, PhD New York University Boston, Massachusetts Massachusetts General Hospital School of Medicine and Harvard Medical School New York, New York Lawrence M. Nogee, MD Johns Hopkins University Boston, Massachusetts Marie M. Egan, MD Baltimore, Maryland Howard Spivak, MD Yale University School of Medicine Tufts University School of Medicine New Haven, Connecticut Philip O. Ozuah, MD Albert Einstein College of Medicine and New England Medical Center Boston, Massachusetts Bruce D. Gelb, MD Bronx, New York Mount Sinai School of Medicine Alda Tufro, MD, PhD New York, New York Alice S. Prince, MD Columbia University College of Albert Einstein College of Medicine and Danielle Laraque, MD Physicians and Surgeons Children’s Hospital at Montefiore Mount Sinai School of Medicine New York, New York Bronx, New York New York, New York Meeting Services and CME Accreditation Registration and CME Desk Hours CME Accreditation Registration will be held in the Lobby of the Hyatt Regency. This activity has been planned and implemented in accordance Registration hours are as follows: with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint Friday, March 26 << >> – 7:00pm sponsorship of The New York Academy of Medicine and the Saturday, March 27 7:30am – 7:00pm Eastern Society for Pediatric Research. The New York Academy of Medicine is accredited by the ACCME to provide continuing Sunday, March 28 7:30am – << >> medical education for physicians. <<THE TIMES ABOVE NEED TO BE SUPPLIED BY ESPR >> The New York Academy of Medicine designates this educational activity for a maximum of 11.0 Category 1 credits toward the Abstract Publication Physician’s Recognition Award of the AMA. Each physician should claim only those credits that he/she actually spent in the All abstracts being presented at the 2004 Eastern Society for activity. Pediatric Research Annual Meeting are printed in this Program Guide, beginning on page 12. Disclosure All abstracts submitted to the 2004 ESPR Annual Meeting, whether presented or not, are being published in the April 2004 Supplement The New York Academy of Medicine relies upon invited faculty to Pediatric Research. Abstracts submitted to the PAS as well as participants to provide educational information that is objective to the ESPR are included in the Pediatric Research publication and as free from bias as possible. In this spirit, and in accordance and are noted by a superscripted “ESPR” after the publication with the guidelines of the session sponsor, faculty participants number (i.e., 236ESPR). ESPR abstract publication numbers in are required to indicate any commercial relationship that might be Pediatric Research will NOT be the same number that is indicated perceived as a real or apparent conflict of interest. in this publication. Abstracts submitted only to the ESPR appear under the Eastern Society for Pediatric Research heading in the CME Procedure Pediatric Research publication. To receive the appropriate number of CME credit hours, it is Audio/Visual Information IMPORTANT! important to do the following: Upon arrival, pick up your verification form at the Continuing All presentations must be made using PowerPoint. Computers Education Desk. (Lobby–Hyatt Regency) and LCD projectors will be provided. Slide projectors will not be provided. Speakers will need to bring their presentations on a CD- On your departure date, turn in your completed verification ROM, ZIP drive, or flash memory. Presentations will be loaded form. <<Where to Turn in Fom?>> onto a central computer during the session prior to the presentation A record of credit will be emailed to each registrant after the activity (i.e., Friday evening for Saturday morning presentations, Saturday concludes. morning for Saturday afternoon presentations, and Saturday afternoon for Sunday morning presentations). THINGS TO DO WHILE IN Speaker Check In REQUIRED! GREENWICH Speakers must have their presentations loaded onto a central Bush-Holley Historic Site computer during the session prior to the session in which the Home of Connecticut's first art colony, presentation is to be made. Please take your materials to the Speaker the Historical Society's facilities include Ready Room/Area in <<LOCATION>>. the circa 1730 National Historic Landmark Bush-Holley House; the circa 1805 visitor center, housed in <<ADDITIONAL INFO NEEDS TO BE SUPPLIED BY ESPR >> a former village post office;