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Cell

Editor Associate Editors Benjamin Lewin Richard Axel Philippa Marrack Rosa Beddington Chris Marshall European Editor Pierre Chambon Diane Mathis Peter W. J. Rigby Joanne Chory Ira Mellman Don Metcalf Senior Editors David Friedman Elliot Meyerowitz Amy Axelrod Phillip Gallimore Tim Mitchison Vivian Siegel John Gerhart Stephen Goff William Paul Joe Goldstein Hugh Pelham Consulting Editor Peter Goodfellow Roger Perlmutter Gregory Gasic Klaus Rajewsky Martin Hemier Danny Reinberg Managing Editor Ira Herskowitz James Roberts Rebecca Kennison Chris Higgins Elliott Ross Robert Horvitz Gerald Rubin Editorial Staff Joshua Sanes Alexander Barnett Tony Hunter Jeff Schell Edward J. Dionne Richard Hynes Matthew Scott Jennifer MacMillan David Ish-Horowitz David Sherratt Martha Sullivan Thomas Jesse11 Jim Smith Peter Kim Frank Solomon Judith Kimble Davor Solter Advertising Roger Kornberg George Sprague Lynn Reznick Parisi - Director John Kuriyan Charles Stevens Jennifer Oneglia - Classifieds Ron Laskey Robert Tjian Christa A. Matukaitis Michael Levine Richard Losick Mike Waterfield Circulation Vivek Malhotra Alan Weiner Marie Arsenault - Manager Owen Witte Heather L. McCormick

Telephone Numbers Principal Office European Office Cell Division of Eukaryotic Editorial: 617-661-7057 1050 Massachusetts Avenue Molecular Genetics Advertising: 617-661-7059 Cambridge, Massachusetts 02138 NIMR USA The Ridgeway, Mill Hill Subscriptions: 617-661-7060 Fax: 617-661-7061 London NW7 1 AA, England E-mail: [email protected] Telephone: (0)181-906-3897 Fax: (0)181-913-8527 E-mail: [email protected]

Cell (ISSN 0092-8674) is published biweekly by Cell Press, 1050 Massachusetts Avenue, Cambridge, Massachusetts 02138. The institutional subscription rate for 1995 is $375 (US), $525 (Europe and Israel), or $460 (elsewhere). The individual subscription rate is $105 (US), $225 (Europe and Israel), or $170 (elsewhere). The individual copy price is $30.

There is no page charge except for intergovernmental organizations ($20 per page). Copyright 0 1995 by Cell Press. Second class postage paid at Boston, Massachusetts, and additional mailing offices. Postmaster: send address changes to Cell, 1050 Massachusetts Avenue, Cambridge, Massachusetts 02138.