C O N T E N T S
OVERVIEW i-vi Resource Base vii Performance viii
1.0 S&T CONTRIBUTIONS 1.1 Aerospace Science & Technology 2 1.2 Biology & Biotechnology 6 1.3 Chemical Science & Technology 29 1.4 Earth Resources & Natural Hazards Assessment 44 1.5 Ecology & Environment 50 1.6 Electronics & Instrumentation 57 1.7 Energy 65 1.8 Food & Food Processing 69 1.9 Health Care, Drugs & Pharmaceuticals 79 1.10 Housing & Construction 90 1.11 Information Dissemination & Products 96 1.12 Leather 102 1.13 Material, Minerals, Metals & Manufacturing 105
2.0 CENTRAL MANAGEMENT ACTIVITIES 2.1 CSIR Society 119 2.2 Governing Body 122 2.3 Advisory Board 123 2.4 Department Related Parliamentary Committee 123 2.5 CSIR Foundation Day 124 2.6 Shanti Swarup Bhatnagar Prize 2003: Presentation Ceremony 126 2.7 Shanti Swarup Bhatnagar Prizes 2004 129 2.8 Directors’ Conference 130 3.0 HEADQUARTERS ACTIVITIES 3.1 R&D Planning Division (RDPD) 135 3.2 International S&T Affairs Directorate (ISTAD) 143 3.3 Intellectual Property Management Division (IPMD) 152 3.4 Technology Networking & Business Development Division 154 (TNBD) 3.5 Human Resource Development Group (HRDG) 160 3.6 Human Resource Development Centre (HRDC) 164 3.7 Unit for Science Dissemination (USD) 164 3.8 Recruitment and Assessment Board (RAB) 165
4.0 DATELINE CSIR 169
ANNEXURES I Intellectual Property from CSIR 189 Ia Foreign Patents Granted 190 II Top Papers published by CSIR 213 III Members of CSIR Society (including Members of CSIR 217 Governing Body) IV Members of the Advisory Board 219 V List of Network Projects 220 VI CAG Report 222 VII PM’s Speech at CSIR Society Meeting 224
O V E R V I E W
The Annual Report for the year 2004-2005 highlights the salient features of the contributions made by CSIR in a wide spectrum of activities, which span from creation of public goods to private goods to social goods to strategic goods. While maiden flight of SARAS was a landmark in CSIR’s contributions to herald the civil aviation industry in the country, the discovery of a new molecule, as a potential drug for cure of deadly disease of tuberculosis, CSIR’s instant response to alleviation of hardships of Tsunami’s victims were the major contributions in other spheres.
During the period under review, CSIR continued to make strides in scientific achievements as well as management reforms. These reform processes and new modes of operation were in consonance with the new demands on CSIR to respond to the dynamic changes taking place in India.
Under new mode of operation, CSIR continued to consolidate its programme delivery through network projects. A large number of knowledge networks spread across and beyond CSIR laboratories were created. The focus of the programmes thus evolved has been to synergise the vast competencies of CSIR laboratories and others within the country. Special attention has been paid towards monitoring and evaluation of these large network projects.
CSIR pioneered New Millennium Indian Technology Leadership Initiative (NMITLI) scheme, which is considered to be India’s largest private public partnership programme. There are 65 private sector companies and 175 institutions involved essentially to capture global technology leadership position and development of technology through consortia of the “best” academic/R&D and industrial partners. A number of NMITLI projects have paid handsome dividends by way of new discoveries. A major initiative was taken during this year to consolidate on the research results from these projects to convert them into major technology missions, e.g. TB Mission with a view to develop the first TB drug from India.
CSIR has been an open and learning system with periodic reviews undertaken through internal and external committees. The ongoing reform process within CSIR owes itself largely to the recommendations of Kelkar Committee Report submitted last year. The committee revitalized the thought process for change management within the CSIR, which has been appreciated widely and emerged as a model for other institutions in India and abroad to emulate.
The process of change within CSIR has also drawn our attention to focus on issues associated with human resource development. The ‘Human Resource Development
i Center’ (HRDC) established during the year 2002 has taken an initiative for setting up of Human Resource Groups (HRGs) in all the CSIR laboratories. The HRDC shall be looking at the human resource development issues centrally at CSIR level; the Groups shall be responsible for meeting the specific HR needs of the laboratories.
More specifically, it presents CSIR’s S&T contributions in the sectors such as Aerospace Science & Technology, Biology & Biotechnology, Chemical Science & Technology, Earth Resources & Natural Hazards Assessment, Ecology & Environment, Energy, Food & Food Processing, Health Care, Drugs & Pharmaceuticals, Housing & Construction, Information Dissemination & Products, Leather, Material, Minerals, Metals & Manufacturing and Metrology. Various activities related to Central Management and Headquarters are also detailed in the Report. The section on ‘Dateline CSIR’ lists the significant events that took place at various CSIR constituent laboratories during the year.
Some of the notable features of the Report are provided below:
SARAS TAKES TO SKIES
SARAS, India’s first indigenously developed, multi-role civilian aircraft took its inaugural flight to skies at 8.20 am on Sunday, 22 nd August, 2004. SARAS will serve as a multi-role aircraft with feeder airline and air taxi operations as its primary roles. It would also be used as executive transport and light cargo carrier, in remote sensing, as aerial research vehicle, coast guard, border patrol, air ambulance and other services. It can take off and land from short semi-prepared runways and is therefore ideally suited for operations in difficult terrains and would help in providing connectivity, especially in the North East India. With potential for such multiple roles, it is expected that SARAS will usher in a vibrant civil aircraft industry in the country in the coming years.
A NEW TB VACCINE
Tuberculosis (TB) is the leading infectious killer of youth and adults. One third of the world’s population is currently infected with the causative organism, Mycobacterium tuberculosis , a Gram-positive bacterium. A candidate vaccine has successfully been evaluated in the form of live Mycobacterium habana in animals. M. habana is an atypical mycobacteria reported non pathogenic in mice, guinea pig and monkey. There is no report of its association with any human disease. The antigens of M.habana cross-react strongly to the antigens of M. tuberculosis , which means that the two mycobacterial strains share antigenic homology.
ii TB MOLECULE BREAKTHROUGH
As a result of private-public partnership programme, launched by New Millennium Indian Technology Leadership Initiative (NMITLI), a new molecule, ‘sudoterb’ for the treatment of TB has been developed, for which clinical trial has been started. This is the first new molecular strain discovered after Rifampicin in 1963. The molecule, which may help reduce the treatment time from eight months to two months, is especially well suited for the poor.
A BIOMARKER FOR THE DIAGNOSIS OF VISCERAL LEISHMANIASIS
IICB identified the increased presence of disease specific biomarker(glycotype) on erythrocytes of patients with visceral leishmaniasis (VL). The over expression of this biomarker has helped in the development of erythrocyte binding assay to monitor the clinical status of visceral leishmaniasis patients, which can detect VL even under field conditions. Only a drop of blood is required for this assay. The assay is cheap, non-invasive and above all is rapid and can be carried out in field conditions. The assay has greater sensitivity and minimal cross reactivity with malaria and tuberculosis. The potential of this discovery has been quickly identified by World Health Organisation (WHO) for its global application and the technology has recently been transferred to an Indian company (Zephyr Biomedical, Goa).
VAXIPRED- COMPUTER AIDED VACCINE DESIGN
VaxiPred, an innovative immuno-informatics tool enabled computer aided vaccine design has been released. This research tool contains components, which synergistically and seamlessly combine the best of research in immunology and immuno-informatics, the offshoot of information technology. VaxiPred is primarily the result of premier research in vaccinology at IMTECH, which has been adequately backed and supported by use of state-of-the-art in information technology by BioMantra. VaxiPred changes the very percept, outlook and approach of vaccinology and immunology. Release of this state-of-the art technology for use amongst the research community has the potential to bring Indian vaccinology at par with world-class research.
ISFET (ION-SENSITIVE FIELD-EFFECT TRANSISTOR)- BASED GLUCOSE BIOSENSOR CEERI has developed ISFET based glucose biosensor. This biosensor comprises an ion-sensitive field-effect transistor (ISFET), which is a metal-oxide-semiconductor field-effect transistor (MOSFET) with the metal gate replaced by a chemical membrane (SiO 2-Si 3N4) responsive to hydrogen ions, producing a solid-state pH- micro-sensor. This has the advantage over conventional biosensor in terms of smaller size, robustness, easy cleaning, minimal need for maintenance, and fast response.
iii OPTICAL FIBRE AMPLIFIER For the first time in India, an optical amplifier for light wave telecommunication network has been developed by CGCRI using erbium-doped optical fibre (EDF) and power semiconductor pump laser source. This device has the potential for use in the propagation of “Fibre to Home” technology in the country.
TRADITIONAL KNOWLEDGE PROTECTION Two NISCAIR journals, Indian Journal of Traditional Knowledge (IJTK) and Medicinal and Aromatic Plant Abstracts (MAPA) , have become part of Non Patent Literature (NPL) of the PCT Minimum Documentation. For the first time journals from a developing country have been included in the coveted list of ‘prior art search journals’. Inclusion of IJTK in the list is yet another feat towards achieving the basic objective of Traditional Knowledge Digital Library (TKDL) for prevention of grant of wrong patents through misappropriation of our traditional knowledge. With this, India has joined the select list of thirteen nations. It shares the seventh position with France & Switzerland. TKDL is serving as a role model for protection of traditional knowledge for various countries like South Africa, African Regional Industrial Property Organization (representing 16 member nations), Singapore, Japan etc.
COMPUTER-AIDED MICROSCOPIC INSPECTION SYSTEM FOR MEDICINAL PLANTS A computer-aided microscopic inspection system, which avoids some of the shortcomings of the conventional microscopic inspection methods, has been developed. The system, HERBAS (Herbs Authentication System) consists of a computer, microscope, digital camera, printer and custom-developed application software. The application software running on the computer allows the user to capture the microscopic images through the digital camera and utilizes them appropriately.
CSIR’S SCIENTIFIC BREAKTHROUGHS The year saw several of CSIR’S significant breakthroughs picked up by prestigious international research publications to be highlighted on their cover pages. Some of these are
From CCMB
“Role of cycline E in cell fate determination in the central nervous system of Drosophila melanogaster ” on the cover page of ‘Nature Cell Biology’, January 2005. The study has led to understanding the mechanism of critical role of c ycline E in the nerve cell fate determination which will help in gene therapy for neural disorders.
iv “Changes in cell shape induced by membrane cholesterol” on the cover page of ‘Experimental Cell Research’, October 2004. “Microbes from cold habitats: Biodiversity, Biotechnology & Cold Adaptation” on the cover page of ‘Cellular & Molecular Biology’, July 2004. It would open up avenues for developing strategies for improving resistance of crop plants to low temperatures and also yield biomolecules of biotechnological potential such as enzymes.
From IICB “Micronuclei as Biomarkers of Carcinogen exposure in populations exposed to arsenic through drinking water in West Bengal, India: A comparative study in three cell types” on the cover page of American Association for Cancer Research, May 2004.
From ITRC “Modulation of P-glycoprotein-mediated multidrug resistance in K562 leukemic cells by indole-3-carbinol” on the cover page of ‘Toxicology and Applied Pharmacology’, February 2005.
CSIR PROVIDES RELIEF IN TSUNAMI HIT AREAS The devastating tsunami that hit the coastal areas of South-East Asia on 26 th December 2004 left behind in its wake a wide swath of death and destruction. With a death toll of 300,000 across Asia, of which around 11,000 reported from the eastern coast of South India and the Andaman & Nicobar Islands, the sea-based earthquake has come to hold the dubious distinction of being one of the largest disasters ever in recent history. It is estimated that as many as 2 million people in India have been rendered homeless, foodless and clothless owing to this fury. A number of CSIR laboratories rose to the occasion to offer their scientific & technical skills and other resources to mitigate the sufferings of those who survived this unprecedented calamity and also to initiate programmes that could help the country to deal with such natural catastrophic events. These offers and initiatives included shelter, food, drinking water and numerous studies that could improve our knowledge and skills to deal with such disasters and their after effects in times to come.
FOOD CFTRI took the mission of providing food for the needy people in the tsunami hit areas. It undertook the largest production of instant food by an R&D laboratory, providing 55 tonnes of food equivalent to nearly 1,80,000 meals. This includes ready to eat meals (upma mix, sambar rice with pickles), high-energy food, baby milk powder, rice, sugar, oil, suji and atta.
v DRINKING WATER CSMCRI has installed Reverse Osmosis (RO) and Electrodialysis (ED) plants in different Tsunami hit areas:
• Nagapattinam - RO Plant (1,500-2,000 litres per hour) installed at Akkaraipettai that is supplying nearly 20,000 litres of water per day. Around 12,000 people benefited. • Andaman & Nicobar Islands – Two RO Units (each of 800-1,200 litres per hour capacity) were installed in Port Blair. • Ayyampettai – The first Electrodialysis Desalination (ED) Unit of 500 litres per hour capacity installed at Ayyampettai (1500 population) is operating smoothly and producing potable water of 500 litres per hour. It is connected to the distribution pipeline and people are getting water in their taps. The second unit was installed at Rajapettai village with a population of around 2000.
SHELTER
CBRI provided backup support in rehabilitation of the devastated areas by providing pragmatic solutions to the repair and retrofit of the existing infrastructure and buildings.
Even though the washed away shelters of most fishermen were non-engineered or semi-engineered, SERC, commissioned a team of scientists to survey the entire coastal stretch from the Chennai to Nagapattinam and prepared a report on structural damage and its assessment. - AFTERSHOCKS
NGRI continuously recorded and monitored the aftershocks of the tsunami. The data was provided to the concerned authorities in Andhra Pradesh on possible effects of such shocks on sea so that appropriate steps could be taken to avoid further loss of life.
EXCELLING IN SCIENTIFIC & INDUSTRIAL RESEARCH OUTPUT
CSIR’s basic research contributions scored an all time high. As a result of researches carried out in the national laboratories over 2660 research papers have been published in internationally peer reviewed journals with average impact factor per paper of nearly 1.90. CSIR was granted 272 patents abroad, again an all time high. 60% share in the total US Patents granted to Indians excluding NRIs and foreign assignees belongs to CSIR.
vi R E S O U R C E B A S E
1. Infrastructural Number
• Laboratories/Institutes 38
• Outreach Centers 39
2. Human
• Total Staff 18251
Total S & T staff 13338
Scientists (Group IV) 4682 Technical (Group III) 2957
Technical (Group II+I) 5699
• Total Administrative& non-technical (includes 4913 isolated staff strength)
3. Financial Rs. crore
• Government budgetary support 1266.47
Government plan allocation 580.77
Government non-plan allocation 685.70
• Extra budgetary resource generation
From contract R & D and consultancy 258.75
Miscellaneous receipts (non R & D) 55.747 Laboratory reserves 88.967
vii P E R F O R M A N C E
1. Science Output Numbers • Papers contributed Number 2668 (2188)
Average Impact Factor Per Paper 1.899 (1.749)
• Patents Filed in India 418 (406) Filed abroad 500 (495) In force in India 1240 (1083) In force abroad 990 (727)
2. National S & T Human Resource Developement Research Fellows/Associates Supported 7640 (6755) Emeritus Scientists in position 119 (137) Pool Scientists (SRAs) in position 186 (206) Research Schemes supported 760 (728) Figures in parenthesis correspond to the previous year 2003-04
viii
T laboratories are functioning at present. 3 at functioning are laboratories and activities research their further to stations laboratories. Some of the establishments have set i country, the Ther of parts different in establishments results. research of utilization and research research in diverse of fields science and technolog of of the Society such as food, fuel, buildings, roads advancement of Indian industry whereas other labora development specific to their respective geographic respective their to experim specific development dea laboratories oceanography, research regional The toxicology. geophysics, aerospace electrochemistry, engineering, mechanical in research with marine chemicals and scientific instruments. There ceramics, and glass electronics, pharmaceuticals, & with problems of interest to specific industries, l care and the new job creation/saving jobs, essentia frontiers of science. of frontiers res basic covers also laboratories CSIR in Research f provide laboratories CSIR teamwork. for call and for their solutions the knowledge and techniques of industry, and even of pure science, are multi-disci standa and testing beneficiation, indust their on of research surveys undertake They work. development Some of the CSIR are resear in laboratories engaged n eea,al h lbrtre r eupe fr a for equipped are laboratories the all general, In CSIR has several programmes relating to water, ener he Council of Scientific and Industrial Research ha Research Industrial and Scientific of Council he national laboratories/institutes in various parts o parts various in laboratories/institutes national & CONTRIBUTIONS CONTRIBUTIONS S&T S&T & CONTRIBUTIONS CONTRIBUTIONS S&T S&T 1 ike ike biotechnology, chemicals, drugs , , etc. A few of these are concerned lly lly to provide S&T base solutions up up survey experimental, or field plinary plinary in character, and require y y and with emphasis on applied are some laboratories concerned ncluding five regional research regional five ncluding more than one branch of science sc sain atce t 16 to attached stations such 9 earch aimed at exploring new exploring at aimed earch rdization. Many problems of problems Many rdization. leather, minerals and metals, and minerals leather, l with problems of industrial of problems with l al areas. al ae t rsn 3 research 38 present at are e tories deal with general needs acilities for such teamwork.such for acilities f the country to undertaketo country the f gy, environment and health pidrsac, including research, pplied ch, ch, which contribute to the s established a network of network a established s cec n engineering, and science il a mtras and materials raw rial na mdcn and medicine ental
S&T Contributions CSIR Annual Report 2004-05 to economic development. In the following, results of a few of the more significant, both basic and applied researches, carried out by the national laboratories are presented sectorally. S&T Contributions S&T 1.1 AEROSPACE SCIENCE & TECHNOLOGY
NAL is a major player in India’s aerospace programmes. It has developed a world class capacity for design, development and fabrication of large components of advanced composites for civilian and combat aircraft, structural testing and analysis, aerospace electronics and systems, innovative capabilities in surface engineering etc. The activities are focused on design, development, fabrication and airworthiness testing of small civilian aircraft and on creating, maintaining and providing high class expertise and world class test and certification facilities.
1.1.1 Progress made under Network projects
Some of the significant achievements project-wise are:
I. CATERING TO SPECIALISED AEROSPACE MATERIALS
The objective of the project is to formulate and execute a structured programme on development and characterization of different specialized aerospace materials and to provide materials related technological services to aerospace organizations.
PROGRESS:
NAL has developed some variants of the pressure sensitive paints and two of the paints developed have withstood 50 blow downs in the NAL high-speed wind tunnel without any performance deterioration. CSIR Annual Report 2004-05 II. HIGH SCIENCE & TECHNOLOGY FOR NATIONAL AEROSPACE PROGRAMMES
The main objectives of this programme are enhancing the capabilities for generating crucial design and certification data for aerospace systems; enhancing the knowledge base through R & D activity for increased self-reliance and freedom; building up new and critical facilities in the area to minimize dependence on foreign test facilities.
2 jigs for weight optimised structure for SARAS complSARAS for structure optimised weight for jigs and composite pressure bulkhead design of SARAS com Composite completed. structured SARAS optimisation fabri under are parts b and actuater gear landing pressure for and VT & HT Configuration the for EICAS and autopilot De finalized. Strec for (HANSA design aircraft Configuration 4-seater the of Configuration PROGRESS: versions of SARAS. optimization and other improvements of SARAS to pro development of critical LRUs with particular releva Civil Aircraft R&D, Civil Aviation Policy Research dev and to project of are the design objectives The SMALL SPEARHEADING CIVILIAN AIRCRAFT DESIGN, III. Models International and Airport C like Bangalore Airports Traffic on-line Air developed. for been have fusion and Algorithms sens multi estimation, parameter and reconstruction demonstrated. and developed braidin of combination using cylindrical) and (flat manufactur for techniques Fabrication delamination. multipl modeling for composites, addressing developed issues related to actuator been / have techniques be to found been has speeds high at flows separated diagn a as paints sensitive pressure of Application PROGRESS: sonar dome of a warship. A model approach has been been has approach model A warship. a of dome sonar simulation RANS and hover in blade rotor helicopter computat incidence, large at wings over flow flows, Some packages were also enhanced to compute real li flow situations like flow on SARAS HANSA-3, aircraf appro (CFD) Dynamics Fluid Computational using NAL, COMPUTATIONAL FLUID DYNAMICS (CFD) Scientific Achievements under non-network prog 1.1.2 DEVELOPMENT & DEVELOPMENT MANUFACTURE 3 sensor debonding and substrate nce to small aircraft; and Weight HANSA;of stretched elopment & & Market Analysis; Indigenous g and resin injection has beenhas injection resin and g ostic tool for complex and 3D and complex for tool ostic ochin ochin International Airport. fe flow situation like separated sign sign and completeddrawings cation. Wing root rib weight rib root Wing cation. very satisfactory. Numerical satisfactory. very or and multi target tracking target multi and or eted. ion of unsteady flow over aover flow unsteady of ion t and missile configurations. e of glass epoxy composites epoxy glass of e of flow past bow mounted bow past flow of duction standards; duction variousstandards; pleted. pleted. Design of assembly empennage layout design layout empennage ae en iuae for simulated been have used to study the liquidthe study to used e vrin finalized. version) hed rammes ach, analysed practical analysed ach, dmgs n smart in damages e lha completed. ulkhead lgt data/path flight
S&T Contributions CSIR Annual Report 2004-05 sloshing in spherical tanks and successfully applied to calculate slosh frequencies in spherical tanks for different fill volume and Bond number conditions. The method was also extended to sloshing in satellite fuel tanks due to prescribed spacecraft rotational maneuvers.
S&T Contributions S&T CO-CURED CO-BONDED COMPOSITE FABRICATION TECHNOLOGY
NAL has developed co-cured, co-bonded technology for fabrication of composite aircraft structures. The impact of this technology on national aircraft programmes is substantial as it reduces the space inventory, reduces down time during maintenance and ensures a higher degree of reliability. This is a national first in a field held closely by international players. The figure shows the fabrication of Trouser duct for TEJAS by this technique.
Trouser Duct for TEJAS
SUPERSONIC COMBUSTOR / SCRAMJET
NAL has successfully demonstrated combustion in supersonic flow regimes using both hydrogen and kerosene. Successful combustion has been achieved in the dual mode i.e. subsonic as well as supersonic flows and thus has fulfilled a major requirement for futuristic launch vehicles. The technology is very useful for futuristic propulsion systems. CSIR Annual Report 2004-05
Demonstration of supersonic combustion
4 is a major contribution for data theseprovided by sensors detectionfor of dam characteri sensor for methodologies Simultaneously, d been has structures aircraft composite in sensors Technology systems. aerospace to application their relatin aspects of number a on working been has NAL MATERIALS SMART received a high degree of appreciation from the aer the from appreciation of degree high a received di flying and static the both in part took aircraft aerospace in area, SARAStook Aircraft to sky thin During the Aero India 2005, as a part of showcasing AERO-INDIA 2005 develope Z been controlcharacteristics of a has Lead actuator using “V-stack” A control technology. vibration active for materials has advance notable Another carrier. aircraft from vital a is This scale. prototype a on demonstrated o version naval the for surface) control (a mousche f alloys memory shape of use Successful flight. in in-situ surface NAL stall, Aero India 2005 structural health monitoring of aircraft component piezo actuator stack 5 splay every day. These aircrafts These day. every splay or deploying and retracting the retracting and deploying or NAL expertise and capabilities input in operating the aircraftthe operating in input e flying display while HANSA while display e flying ospace community.ospace age age has developed. Thisbeen been the application of smart of application the been vlpdad demonstrated. and eveloped fgtr icat a been has aircraft fighter a f sation and interpretation of interpretation and sation o ebdig ir optic fibre embedding for roae iaae (PZT) Titanate irconate g to smart materials and materials smart to g t ehne h flutter the enhance to d s
S&T Contributions CSIR Annual Report 2004-05 1.1.3 Human Resource Development
• A special ISO 9001-2000 Auditors Course for Internal Auditors was held.
• CSIR Programme on Youth for Leadership in Science (CPYLS) was held. 45 top ranking students from Karnataka State participated and were certified. S&T Contributions S&T
1.1.4 Recognition & Awards
Technology Shield NAL
H. K. Firodia Award Dr. T. S. Prahlad, NAL
National Aeronautical Prize for 2004 of the Dr. K. Y. Narayan, NAL Aeronautical Society of India
Distinguished Alumnus of IIT-Chennai Dr. P.R. Pai, NAL for 2004
Raman Research Fellowship Dr. P.K. Panda, NAL
Mechanical Engineering Design Award Dr. D.B. 2004 of the Institution of Engineers Venkatasubramanyam, NAL
1.2 BIOLOGY & BIOTECHNOLOGY
CSIR continues to make wide ranging contributions in the areas of genomics, control of gene expressions, recombinant DNA products, molecular & cellular biology, tissue culture, agro-biotechnology and fermentation. The work in these areas is not only getting published in high impact factor journal (Nature-Cell Biology, CSIR Annual Report 2004-05 Science, Langumir etc. for example) but it is gratifying to note about its getting highlighted on the cover pages of different issues of journals as well. Work on multi locus, BKm derived probe for DNA fingerprinting has placed India among the first few nations, which has its own DNA finger printing probe. CSIR has done pioneering work on leishmania, cholera cataract formation in the eye, apoptosis, and antibacterial activity of plant sources. It has also developed several PCR based marker and diagnostic systems. CSIR has to its credit development of many new and improved strains for several medicinal, aromatic and flowering plants.
6 Molecular Molecular of analysis bacterial diversity by cultur PROGRESS: processes. and sour major a as it exploiting of goal ultimate with cul and dependent culture both through exploitation diversit microbial to project envisages exploit The Fusarium isolates showed high tolerance to desiccation.to tolerance high showed isolates toler stress their for screened high were with solubilization Carolina isolates North bacterial and one Twenty phosphate, phosphates. ferric and phosphate tric of solubilization the in efficiency high shows tea rhizosphere, was studied for solubilization of • • AND EXPLOITATION EXPLORATION OF MICROBIAL WEALTH I. a project-wise achievements significant the of Some Progress made under projectsNetwork 1.2.1 were obtained for each sample.each for obtained were 1000 than More cloned. were samples ETP Gharda and metageno from obtained products PCR Eubacterial The amplification for used was obtained DNA metagenomic Thirty Thirty eight pseudomonades were screened for their The fungus fungus The uncharacterized bacteria. The results indicate that hot spring mat microbial 96% identity) and an uncultured bacterium (1 clone identity % 88 clone (1 mobilis Tistrella identity), Thi identity), 95% and 91% clones, (2 Cyanobacteria terraneu Desulfocaldus to related Clones identity). Halot to related reveale bacteria by clones) BLAST (58% dominated by analysis Sequence gene. 16S the of t more obtain to sequenced were DNA mat metagenomic mat: microbial spring Hot samples: ETP PROCESS INDIA FOR NOVEL COMPOUNDS AND BIOTRANSFORMATION spp., infecting gladiolus and carnation to carnation and assess gladiolus infecting spp., Eupenicillium parvum Eupenicillium o nesad h mcoil iest o EP sampl ETP of diversity microbial the understand To bu 2 coe fo a 6 gn lbay from library gene 16S a from clones 20 About , isolated and recorded for the first time from time first the for recorded and isolated , 7 phosphate substrates. The fungus y of commercialof country the for y ce of biotechnological products biotechnological of ce e independent method ne gis dscain Nine desiccation. against ance lim hsht, aluminium phosphate, alcium re: ), Betaproteobacteria (1 clone, (1 Betaproteobacteria ), community possesses unique 95% identity) were obtained. ture independent methods, independent ture fiiny o phosphate for efficiency s (2 clones, 94% identity), 94% clones, (2 s antifungal antifungal activity against omonas sp. (1 clone, 95% clone, (1 sp. omonas hiobacillus sp. (89%-90% sp. hiobacillus the role of siderophores the role n Msore rock Mussoorie and ta mt ape is sample mat that d recombinant colonies recombinant mic DNA of Merind of DNA mic han 500 bp sequence bp 500 han of 16S RNA genes. RNA 16S of : OF es
S&T Contributions CSIR Annual Report 2004-05 in fungal antagonism. The results indicate the production of antifungal metabolites along with siderophores by 5 isolates.
Twenty-two Trichoderma isolates antagonistic to Fusarium spp. infecting gladiolus and carnation were characterized for their diversity for RAPD markers. Significant genetic variability was observed and the similarity coefficient values ranged from S&T Contributions S&T 0.05 to 0.60 amongst the isolates. The groups that emerged from cluster analysis represented two different species, with group I representing T. harzianum and group II representing T. viride.
II. MOLECULAR BIOLOGY OF SELECTED PATHOGENS FOR DEVELOPING DRUG TARGETS
Molecular biology description of a given pathogen plays major role in the development of a new drug for the given disease. The project envisages in depth study of molecular biology of a few pathogens for developing drug targets, namely for Mycobacterium tuberculosis, Plasmodium falciparum, Leishmania Donovani, Fungal pathogens (C. albicans and A. fumigatus), Enteric pathogens (V. cholerae, S. dysenteriae and H. pylori).
PROGRESS:
glnE (Glutamine Synthetase ) as a novel drug target in M. tuberculosis: BLAST2 analysis of sequences of the predicted N-terminal and C-terminal domains of GlnE (Glutamine Synthetase), full-length ATase was concluded to contain two duplicated homologous domains. Protein secondary structure prediction using PHD server for the predicted N-terminal and C-terminal domains showed similar prediction of the helices and ß-sheets. Sequence alignment of GlnE from 59 bacterial organisms was analysed using ClustalW . It was found that the residues responsible for forming the phosphate binding loop and the metal binding residues in E. coli were conserved in Mtb as well. The phylogenetic trees for the conserved regions of GlnE and its substrate GlnA1 have been generated to study the co-evolutionary pattern.
CSIR Annual Report 2004-05 Meanwhile, glnE (2985bp) has been successfully cloned in pBlueScript (SK+), which has been confirmed by PCR amplification of glnE from the recombinant clone and by restriction digestion with NotI .
III. DEVELOPING CELL & TISSUE ENGINEERING
The project targets to develop commercially sustainable and viable products in the field of Cell & Tissue engineering with applications in modern medicine, agriculture and basic sciences. It will come through new technologies and methodologies for maintaining and growing cells in vitro , developing new types of cells and tissues for transplantation into new hosts including humans, methods
8 plants: IV. TOXICOGENOMICS TOXICOGENOMICS OF POLYMORPHISM IN INDIAN POPULAT IV. gis rbe. ag-cl tsu clue n bior and culture production tissue of biomass Large-scale rabies. against wo strategy This established. been has glycoprotein tobacco plant cells and the large-scale production glycoprotein virus rabies the of system deve expression been has trees mango alphanso of diversity the of alphanso mangoes has been done. A database using Prelimi molecules res of specific characterization chemical identified. been have euchroma Arnebia from expression pathways involved in the production of c ne Some established. been has colors shikonin-based tde o te ai poete ad plctos of medicine applications and properties basic the on Studies PROGRESS: etc. origin animal c in compounds important commercially preparing for isolation and and isolation be has technology A management. their and leukemias categories for different characterizing established and fluorescence activated cell sorting. Improved d potent stem cells (SP cells) from the bone marrow u fetal liver cells, limbal cells, etc. ske A astechnique such h tissues human and rodent different from diseases. for the maintenance of cybrid cells to develop new establishe based oftherapies human A diseases. new cultu cell been has pre-clinical mice do to tissues human of transplantation SCID/Hu of maintenance and is being tested to develop this protocol for human new m in Leishmaniasis of A treatment the for established patients. vitiligo of treat to use their for that are genetically predisposed for differential i t the screen and exposure, toxic for biomarkers the basis molecular the understand to aims project The Isolation, characterization, production and applica TO INDUSTRIAL CHEMICALS FOR DEVELOPMENT OF BIOMARKE ise utr bsd re elsse fr h co the for cell-system free based culture tissue A : Significant progress has been made in the charactethe in made been has progress Significant in vitro in growth of human melanocytes in serum free defined defined free serum in melanocytes human of growth Swertia chirata and 9 Rauwolfia serpentina as been standardized to isolate highly oxic response. It will help to design application. A facility for breeding of acute lymphocyticchildhood of of tobacco plants expressing this therapies for neurodegenerative sing a simple staining technique iagnostic methodology has been ponsible for the unique flavourunique thefor ponsible hrpui pooo hs been has protocol therapeutic studies and develop new cell new develop and studies re re system has been developed ouse models and its potentialits and models ouse of the toxic response, identify response, toxic the of ommercially ommercially important colors ndividuals in the populationthe in ndividuals DNA markers to understand uld be used for vaccination for used be uld the in established been has tion of special products from tm el i regenerative in cells stem atr ae mtos for methods based eactor w components of the gene the of components w letal muscle bone marrow, bone muscle letal oe. taseto and transfection A loped. ells and tissues of plant or plant of tissues and ells nsadrie fr the for standardized en ay dniiain and identification nary told rdcin of production ntrolled have been established. rization of stemcells of rization fr arig out carrying for d media ION RS
S&T Contributions CSIR Annual Report 2004-05 suitable strategies for reducing the risk of the chemicals, mitigation and treatment of the toxic response, and adoption of preventive methods for the susceptible individuals.
PROGRESS: S&T Contributions S&T Assessing natural variations in gene expression in humans by comparing with monozygotic twins using microarrays: Gene expression profiling in blood leukocytes with thirteen individuals (including five pairs of monozygotic twins) on 10,000 genes using HG U95Av2 oligonucleotide microarrays was done. The proportion of differentially expressed genes between monozygotic twins was low (0-1.76%). Variation in expression of genes between monozygotic twins can be classified as ‘random variations’. Genes exhibiting random variations did not show clear preference to any functional class, although ‘signaling and communication’ and ‘immune and related functions’ generally topped the list. The extent of variation in gene expression increased in comparisons between unrelated individuals (0.37%- 14.13%). Most of the genes (89%) exhibiting random variations in twins also varied in expression in unrelated individuals. As with twins, ‘signaling and communication’ topped the list and substantial variations were observed in all three categories: least variable, moderately variable and most variable. A striking outcome of this study was that the housekeeping genes were nearly insensitive to random variations but appeared to be more susceptible to genetic differences.
ArrayD: A general purpose software for microarray design: Software called ‘ArrayD’ is developed that offers various alternative design solutions for an array given a set of user requirements. The user feeds the following inputs: type of source plates to be used, number of gene probes to be printed, number of replicates and number of pins to be used for printing. The solutions are stored in a text file. The choice of a design solution to be used will be governed by the spotting chemistry to be used and the accuracy of the robot. ArrayD is a software for standard cartesian robots. The software aids users in preparing a judicious and elegant design, universally applicable and is available at http://www.igib.res.in/scientists/arrayd/ CSIR Annual Report 2004-05 arrayd.html.
V. DESIGNING ANIMALS AND PLANTS AS BIO-REACTORS FOR PROTEINS & OTHER PRODUCTS
The project envisages designing of transgenic plant, animal, and yeast bioreactors, to develop genetic transformation technology in novel hyper expression systems, to cell exploit bioreactors for production of high value biopharmaceuticals and to construct Gtases library for biotransformation (glucosylation) of natural products.
10 eeomn o gntc rnfrain ehooy in technology transformation genetic of Development production: Designing of transgenic plants, animals and yeast b Down-stream processing: Down-stream nigricans collagen) from the isolated collagen has been estim been has collagen isolated the from collagen) metabolites and intermediates is in progress. progress. in is intermediates qu and and metabolites metabolites alkaloid ergot for analyzed been Claviceps through developed being is system associative ergot completed. completed. Collagen (in small amounts) from the spo isolated and light microscopy and scanning electron ind the from network collagen and Spicules weight). carbohydrates and protein of content total sponges, coast has been made and these have been taxonomical 95 of collection A systems. bioreactor membrane and to up-scaled being are cultures Ginseng LC-MS. and qualitati and quantitative to respect with analyzed bioreactor system: system: bioreactor Cell exploit bioreactors for production of high val high of production for bioreactors exploit Cell expr hyper novel for developed being is system This recombi homologous for vector chloroplast second of screened. being now are transformants chloroplastic deve been has recombination and transformation mediated biolistic vector transformation chloroplast One to immobilization for TF production. TF for immobilization to properti its and achieved been has purification PPO resi site active to respect with characterized been as matrix as well thefrom plant admixture has been and cecropin gene in yeast yeast in gene cecropin and Genes: PROGRESS: Transformation protocol: protocol: Transformation hand. in already is virus rabies of gene G been has designed for catalase cloning SOD, and which was PPO cloned in expre of Cloning from characterized. “Cecropin” gene native the characterized sequenced, was gene The optimization. Hyoscyamus
h teaetc ee AT ws yteie wt cod with synthesized was “AAT” gene therapeutic The has been isolated and hydroxy proline content (mar content proline hydroxy and isolated been has as mycelia a of simulation natural Sclerot system. and and Cicer Three chloroplast transformation vectors have been been have vectors transformation chloroplast Three being developed. Cloning and expression analysis o analysis expression and Cloning developed. being
AAT purification protocol both from the native tiss native the from both protocol purification AAT Pischia h tasomto ad eeeain rtcl for protocols regeneration and transformation The is in progress. in is Drossophila melanogaster melanogaster Drossophila 11 Panax ioreactors for therapeutic protein ue biopharmaceuticals:ue dues and structural attributes.structural and dues ated. microscopy studies have been ve ginsenosides through TLCthrough ginsenosides ve developed. Purified hasAAT Purified developed. were estimated (mg/gm dry (mg/gm estimated were ssion vector. The glycoprotein es characterized with respect with characterized es nges nges carried out. carried Several putative Cloning and reconstitution and Cloning ly identified. ly In identified. the collected ession bioreactor system. bioreactor ession cultured ovaries harboring ovaries cultured 10-20 litre scale using airlift using scale litre 10-20 nation is at advanced stage. advanced at is nation als utrs ae been have cultures callus ividual sponges have been have sponges ividual sponges from Mandapam from sponges n cnimd Similarly confirmed. and niaie slto o the of isolation antitative civd Pies were Primers achieved. oe hpr expression hyper novel Iricinia Iricinia fusca oe fr homologous for loped ia ia of lines haveselected ker amino acid for acid amino ker a coe and cloned was and and n usage on designed.
Petrosia In vitro In f AAT f ue
S&T Contributions CSIR Annual Report 2004-05 Construction of Gtase/Gdases library for biotransformation of natural products: A set of five Gdases of unique physico-kinetic characteristics has been identified. The set includes usual gluconolactone inhibition sensitive enzymes, gluconolactone inhibition insensitive, alpha-link specific, beta-link specific, conjugated gluco- specific and conjugated galacto-specific. Two GDases have been purified. A high
S&T Contributions S&T temperature active GDase has been isolated and patent has been filed. Radiochemical assay screening (primary) has been carried out for progress towards the Gtases using artificial and natural substrates. 4-NP glycosylating GTases have been detected in several medicinal plants. GTases for geraniol, andrographolide, oleonolioc acid and some putative endogenouis substrate specific Gtases have been detected. VI. MEDICINAL PLANT CHEMOTYPES FOR ENHANCED MARKER AND VALUE ADDED COMPOUNDS
The project envisages to enhance the production of around 20 commercially important high value drug molecules present in medicinal plants viz. Artemisia annua, Acorus calamus, Bicopa monnieri, cathranthus roseus, Picorrhiza kurroa etc.
PROGRESS:
Artemisia annua : The first chemotype tagged through marker assisted breeding of this network programme (named CIM-AROGYA) was released and licensed to M/s Themis, India and M/s Vital Health Care for commercial exploitation. The chemovar has distinct DNA fingerprints, unique globular canopy, high biomass yield (553.0 q/ha fresh herb; 48.89 q/ha dry leaf and I.0% artemisinin against 438.4 q/ha fresh herb, 42.30 q/ha dry leaf and 0.5% artmisinin in best variety Jeevan Raksha). CIM-Arogya has now being multiplied for seed production for targeting 25,000 ha area of its plantation to make India a major global supplier of this anti- malarial molecule.
Andrographis paniculata : Based on breeding and agronomic trials of the selected
CSIR Annual Report 2004-05 chemovars at two locations, the genotype AP-3 named as “CIM-MEGHA” has now been released as an improved cultivar (variety) for commercial cultivation in the country. The chemovar is characterised by open canopy type with a branch angle of 60 0 from the main stem, early maturing, tolerant to iron deficiency, 32-40 q/ha herb yield with 2.33-3.18 % andrographolide (against 1.79% in Check) and 0.76- 1.32% neo –andrographolide content. One-step chemical conversion of andrographolide into Isoandrographolide with 90% recovery has been developed. A new diterpene named as “COR-002” has been identified as a novel marker in this plant. The new molecule is an isomer of andrographolide. Also, two new flavonoids named as 5,7-dihydroxy-8,2’- dimethoxy-flavone and 5-hydroxy-7,8- Di- methoxy flavone (andrographosides) have been isolated that show potent anti- neoplastic activity against mouse myeloid leukemia cells .
12 Podophyllum hexandrum crs calamus Acorus irrhz kurroa Picrorrhiza ef ic hs en eeoe o te is tm in time first the for developed been has discs leaf plants in herb.thisin plants of bottleneck biggest the remove will breakthrough isnhss HGCA n HGCA euts hv be have pathwa reductase pathway. HMG-CoA Irridoid and the HMG-CoA in biosynthesis, involved genes Three demand. la a is which catapol, into biotransformed been has for isolated been have PK-3 and 6-O-feruloylcatapol maint being is n markers new Four standardized. been have recovery m 10 chemovrs from markers these of quantification of microanalytical plants 50000 about a yield a few root Kashir atlocationsincluding 3 in multiplied g/plant 200-250 with and respectively) double double bond activation reaction followed by C componentundesirable of the oil) into a novel neol h fr o Fr Blei fr amr. e polysacc New named is farmers. This (MGM)”. roots. the for of extract aqueous forming be Bulletin has Marker promoting Farm health and immunomodulatory of form the de been has returns maximum for crops season winter requiring growth phase, harvesting schedule, spacin concrete onrecommendations optimal time planting for package Agrotechnology Ha. 500 about is far so q/ 83.4 yields variety harvestable roots and is tolerant to leaf The blight di farmers. to distribution a stable genetically first India’s as released been expdpyltxn 4-eehl deoxypodophyllo- a picropodophyllo-toxin, iso- 4’-demethyl new 6 isol been have also glucoside deoxypodophyllo-toxin podophyllotoxin, picropodophyllotoxin, to addition deoxypodophyllotoxin, In standardised. podophyllotoxi molecule marker detecting for Method enabl devised, been have herb this in dormancy seed Catharanthus roseus Catharanthus Also, a method for converting â-asarone into 2,4,5 Chlorophytum borivilianumChlorophytum has industry, cosmetic and flavor in used widely is : : hmcl oiiain f -srn (h predominant (the â-asarone of modification Chemical : he hmvr rc i Pcoie o I (. an (4.5 II or I Picroside in rich chemovars Three : A method for inducing direct shoot bud regeneratio bud shoot direct inducing for method A : New mechanical and hormonal treatments to break st : One of the Chemovar, named as “CIM-OJ”, has now 13 6 -C sease. Area sease. Area covered theby variety 3
nd uniform variety of Musli for Musli of variety uniform nd trimethoxybenzeldehyde, trimethoxybenzeldehyde, which dimerisation has been achieved. farmers’ field. A population of A population field. farmers’ ignan with with ignan 65% recovery using been achieved. been g, intercroping with rainy and
. roseus C. commercial cultivation with cultivation commercial chemoprofiling. Picroside-I chemoprofiling. aie n duei du in drug diuretic and xative ated for selection.chemovarfor ated , sowing rates, sowing rates, , putin crucial ing up to 93% germination. 93% to up ing eeomn o transgenic of development pat aeil ih 90% with material plant g e n ad n ae being are and hand in re a ues hs moderate has tubers, Ha amely apocynin, androsin, apocynin, amely s Msi Glucomannan “Musli as veloped and published in published and veloped i 20 g ln tissue plant mg 2.0 in n nml, Thiamine namely, y ie. ehd for Methods ained. n sltd rm gel from isolated en Ti technological This . akr namely markers n eune for sequenced en d 4-demethyl nd aie based harides . %, 3.9 d n from n toxin, rong but
S&T Contributions CSIR Annual Report 2004-05 Swertia chirayita : The eight accessions showed 0.01-0.59% of the target marker amarogentin from Swertia chirayita . A new marker compound mangiferin in Swertia chirayita is also isolated. An efficient micropropagation technique has been developed and patented. Four to ten weeks old in vitro -raised shoot cultures were analysed for marker molecules and were found positive. The content of these
S&T Contributions S&T markers in 8 weeks old tissue culture varied from 0.07-0.085, 0.03-0.06 and 0.10- 0.70, respectively. Bicopa monnieri : The fresh weight as well as dry weight (dry matter accumulation) at both 90 DAP and 120 DAP were significantly affected by FYM levels as well as plant spacing. Significantly higher yields were obtained with the application of 40 t FYM as compared to 20 t/ha. Also the plant material collected from Joginder Nagar gave higher yield than the material collected from Toru. Amongst the different plant spacing closer spacing of 20x20 cm gave significantly higher yields.
VII. DEVELOPMENT AND COMMERCILISATION OF NEW BIOACTIVES AND TRADITIONAL PREPARATION The objectives of the project are to discover new single molecules as drugs and take them to the IND stage for diseases of interest to India and to the international community; Discover and develop herbals which function through different, mechanisms including metabolic activation and which are based on synergism; Introduce combination drugs including the use of bioenhancers which themselves are not drugs but increase the effectiveness of the drug; Introduce formulations and novel delivery systems which may be target specific; and Discover and develop new herbal pest management agents which influence the pests in the desired fashion but are safe for humans.
PROGRESS:
Around 12000 samples were bio-evaluated against various diseases and disorders [viz., malaria (4600), tuberculosis (3000), filaria (3600), hypertension (600),
CSIR Annual Report 2004-05 anxiety (85), depression (70) and dementia (110). Samples found active are at various stages of confirmation and reconfirmation.
1.2.2 Scientific Achievements under non-network programmes
Apart from network projects CSIR is making S&T progress in non-network mode also. Some of the significant achievements during the year are highlighted below:
CYLIN E IN CELL FATE DETERMINATION OF DROSOPHILA MELANOGASTER CCMB has examined the process by which cell diversity is generated in neuroblast (NB) lineages in the central nervous system of Drosophia melanogaster. It has been
14 DROSOPHILA MELANOGASTER MELANOGASTER DROSOPHILA rspia eaoatr ( melanogaster Drosophila a model, the validate to study a conducted has ITRC s in fate cell regulating in CycE for role critical rol minor haveto seem cycle cell the componentsof transf reverse induces CycE ectopic whereas NB6-4a, sublineage. Loss of of Loss sublineage. genes A genes the input of any homeotic gene, whereas NB6-4a line shown that the NB6-4t lineage represents the ground (MMS), (MMS), first first division of functions NB6-4t, upstream of lyaig agents Alkylating melanogaster eonzdcrioes ee sd Bify tid in third Briefly, used. were carcinogens recognized the G1 the chimera loses its protective abilities completely. completely. abilities protective its loses chimera more effective chaperone in the case of alpha BNAC alp and A alpha human between domain N-terminal the the N-terminals of alpha A and alpha B crystallins CCMB has generated two chimeric proteins, alpha ANB ACTIVITY OF PROTEINA CHAPERONE-LIKE LENS controto comparison in agents, alkylating four the increase dependent dose a showed Results performed. pr were suspensions cell single out, dissected were fr gut mid anterior 2h, ± 98 At 24h. for 1.0mM) and h cl lns etd A lwr hre ais h c type 55° C.at the than more active the wild ratios bee also has charge lipase mutant A lower DNA. of At transcription tested. lines cell the t as efficient moieties as were molecules hydroxyl These synthesized. with several lipids new Further, CCMB has developed several cationic lipid formulati SYSTEMSDRUG DELIVERY DELIVERY AND GENE cataract.as such diseases s design to leads give useful may which crystallin, chapero the enhance to approach engineering protein cycline DmCycE (CycE). CycE, (CycE). DmCycE cycline bd-A N -ethyl- were fed different concentrations of EMS, MMS, ENU and and N Abd-B. i.e. -nitrosourea (ENU) and cyclophosphamide (CP) which which (CP) cyclophosphamide and (ENU) -nitrosourea CycE ehl ehnsloae ES, ehl methanesulfo methyl (EMS), methanesulfonate ethyl , NB6-4a lineage is specified by down regulating lev regulating down by specified is lineage NB6-4a rgn R Oregon function causes homeotic transformation of NB6-4t NB6-4t of transformation homeotic causes function + FOR GENOTOXICITY ASSESSMENT GENOTOXICITY FOR , o evaluating for ), which is asymmetrically expressed after the after expressed asymmetrically is which 15 pros egment-specific neural lineages. neural egment-specific This study provides a promising provides a study This and have been swapped. Swapping l. age is specified by the homeotic chimera, whereas alpha ANBC om control and treated larvae treated controland om trategies to tackle chaperone- tackle to trategies he dihydroxy analogue in all in analogue dihydroxy he e in this process, suggesting a suggesting process, thisin e epared and Comet assay wasassay Comet and epared ons for efficient gene delivery. state, which does not require n isolated, which is 6 times6 is which isolated, n toi lpd ehne the enhance lipids ationic C and alpha BNAC, in which
star larvae (74 ± 2h) of of 2h) ± (74 larvae star ormations. However, other However, ormations. gcm oai cl genotoxicity. cell somatic mdfe Cmtasy inassay Comet modified elk atvt o apa - alpha of activity ne-like in DNA damage with all with damage DNA in n h ha gop were group head the in ha B crystallins makes a makes crystallins B ha to specify the neuronal and CP (0.05, 0.5 els of els nate D. to is
S&T Contributions CSIR Annual Report 2004-05 “CIM-GROW”- A HIGHLY EFFECTIVE PLANT GROWTH PROMOTER
CIMAP has selected a superior bacterial strain ( Bacillus sp CIMAP B1) on the basis of its influence on the enhanced growth of several medicinal and aromatic plants and unique antagonistic behavior against wide range of fungal pathogens known to infect medicinal and aromatic plants. The strain was exploited for the S&T Contributions S&T development of the product, designated as 'Cim-Grow' using semi-synthetic medium for growth and multiplication on the simple carrier medium (vermicompost) in polyethylene bags. It is considered to be a safe and effective product due to rapid multiplication in the carrier medium and formation of resistant spores. 'Cim-Grow' was tested alone and in different combinations to test their effectiveness on the plant growth and productivity of geranium. It produced 298.5 g / pot herb yield when treated alone. The increase was recorded to be 95% over untreated control (153.1g/plant). The combination of 'Cim-Grow' with G. aggregatum increased herb yield by 102.9% over control. In combinations of other bio-inoculants, viz. G. aggregatum + Streptomyces sp., it produced 346 g/pot herb yield which was recorded to be 126.2% more than that with untreated control.
SWEET SMELLING PEPPERMINT GENOTYPE ‘CIM-MADHURAS’
CIMAP has developed a method to allow open pollination in the available parent cv Kukrail followed by single seed progeny selection through chemoprofile and aroma matching the best available commercial samples of oil. A sweet smelling chemotype 'CIM-Madhuras' is produced as a result. `CIM-Madhuras' were produced 51 kg herbage per 25 m 2 plot, which was highest compared to all the control varieties. The herb contained about 0.65% oil.
“CALLITERPENONE“ A NATURAL PLANT GROWTH PROMOTER FROM CALLICARPA MACROPHYLLA
CIMAP has isolated Phyllocladane diterpenoids from Callicarpa macrophylla, which shows remarkable plant growth promoting activities in various pot, tissue culture CSIR Annual Report 2004-05 and field experiments. Among Calliterpenone and its four derivatives valuated for plant growth promoting activities, calliterpenone was found to be the best, for seed germination, root growth, and overall growth of the plant, even better than
GA- 3 and IBA the commonly used plant growth promoters. A bench scale process for isolation of calliterpenone has been developed (0.4-0.9% yield).
“CIM-LIV”- A HIGH SILYMARIN YIELDING CULTIVAR OF MILK THISTLE
Milk thistle, Slibum marianum is an important medicinal plant and has considerable market potential and is used in various drugs for liver protection. CIMAP developed a high yielding cultivar “CIM-LIV” of Slibum marianum, which possesses 2.8%
16 IN VITRO on orbital shaker facilitated rapid growth and morp and growth rapid facilitated shaker orbital on embryogenic callus along with tiny somatic embryos laborato for higher consistently was rate induction Provasoli enriched seawater (PES) medium showed on cal cultured explants the of 80% than More cultures. pigmented uniseriate filamentous callus of callus filamentous uniseriate pigmented plants thr whole somaticto of embryos regeneration SCI a scesul dmntae i demonstrated successfully has CSMCRI ALVAREZII (DOTY) process for the hepatoprotective agent silymarin fr silymarin agent hepatoprotective the yie for process silymarin The hectare. per seeds q 12-14 yields t is cultivar this of plant The silymarin. of yield three pot processes with yield between 43.5 to 53% 53% to 43.5 between yield processeswith pot three h 10-12 in 85-88% yield, higher with acid artelinic M (DHA). dihydroartemisinin products, intermediate pots. CIMAP has adeveloped one-pot process, which and alkylation (reduction, steps three in prepared ( “CIM-CHANDNI”- HIGH YIELDING NEW VARIETY OF CLARYSA level. pilot to scaled already are involved / seeds kg (40 level plant pilot to up scaled being per seed gms (100 scale bench on developed also was vial wtrslbe eiaie o artemisinin. of derivatives water-soluble available testing under preclinical and has been considered a Clraysage ( antimalarial activity antimalarial Lamiaceae, tblt i auos ouin n eteey hr p short of extremely derivative water-soluble and another artelinate, solution aqueous in stability its but malaria cerebral of treatment the in useful pr artesunate, sodium derivative, water-soluble The FOR DRUG ACI ARTELINIC ANTIMALARIAL POT PROCESS ONE acetate are about“CIM-Chandni” in and 52.4%, 26.2% yield is 20 kg against 14 kg of control. The major “CIM-Ch as named variety flower white the developed its refreshing and long lasting note and also posse AVA SCLAREA SALVIA is cultivated is for cultivated production a of s oil- essential SOMATIC EMBRYOGENESIS FROM FROM KAPPAPHYCUS SOMATIC EMBRYOGENESIS Salvia sclarea ) in in vitro ), ), an important aromatic perennial temperate plant as well as vivo 17 to Kappaphycus alvarezii Kappaphycus vitro n artemether oil constituents linalool and linalyl artemisinin sses medicinal properties. CIMAP all with erect growth habit and habit growth erect with all utility is impaired by its poorits by impaired is utility batch). Some of the processesthe of Some batch). oai ebygnss and embryogenesis somatic s the best amongcandidate the ry-adapted plants. Transfer of Transfer plants. ry-adapted om the plant the om ours as compared to prior art prior to compared as ours to liquid medium and swirling in 4 to 5 days. 5 to 4 in hydrolysis) in three differentthree in hydrolysis) h genesis of somatic embryossomatic of genesis h ough micro-propagules from micro-propagules ough Basically Basically d otn i 3 k/a The kg/ha. 35 is content ld 1.5% (w/v) agar solidified agar (w/v) 1.5% does does not isolation require of prd rm reiii is artemisinin from epared respectively. lus development. The callus batch). The process is now is process The batch). and and andni” whose per hectare per whose andni” ty atlnt produces artelinate ethyl am hl-ie Sodium half-life. lasma ource todue of fragrance osse comparable possesses arteether artelinate Silbum marianum Silbum (Doty) in axenic in (Doty) . . It is currently GE s being is D of family
S&T Contributions CSIR Annual Report 2004-05 into micropropagules that grew into whole plants in subsequent cultivation in the sea. The daily growth rate of one tissue cultured plant was monitored for seven generations in field and found to be as high as 105-1.8 times over farmed plants.
INHIBITION OF BCR-ABL TYROSINE KINASE BY CHLOROGENIC ACID S&T Contributions S&T IICB has found that chlorogenic acid (Chl) induces apoptosis of several Bcr-Abl– positive chronic myelogenous leukemia (CML) cell lines and primary cells from CML patients in vitro and destroys Bcr-Abl–positive K562 cells in vivo. In contrast, this compound has no effect on the growth and viability of Bcr-Abl–negative lymphocytic and myeloid cell lines and primary CML cells. Sodium chlorogenate (NaChl) exhibits 2-fold higher efficiency in killing K562 cells compared with Chl. The results indicate that inhibition of Bcr-Abl kinase leading to activation of p38 mitogen-activated protein (MAP) kinase may play an important role in the anti- CML activity of chlorogenic acid.
POLYKETIDE SYNTHASES
CCMB studies show that the superfamily of plant and bacterial type III polyketide synthases (PKSs) produces diverse metabolites with distinct biological functions. PKS18, a type III PKS from Mycobacterium tuberculosis , displays an unusual broad
specificity for aliphatic long-chain acyl-coenzyme A (CoA) starter units (C 6 to C 20 ) to produce tri- and tetra-ketide pyrones. The crystal structure of PKS18 at 2.25 Å resolution reveals a remarkable 20 Å substrate-binding tunnel, hitherto unidentified in this superfamily of enzymes. This remarkable cavity, extending from the active site to the surface of the protein, is primarily generated by subtle changes of backbone dihedral angles in the core of the protein. Mutational and functional analysis of this cavity emphasizes its significance in substrate specificity and also offers new insights into the product release mechanism. This first bacterial type III PKS structure underlines a fascinating example of how delicate changes in protein architecture can generate metabolite diversity in nature. CSIR Annual Report 2004-05
A surface representation of PKS 18 shown with the novel substrate binding tunnel perpendicular to the plane of the paper.
18 h-Tae lae wt [a- with loaded Rho-GTPases bacter the of pathogenesis in aid may activity this downre to Rho-GAP a as functions tuberculosis M. of nucleotide-binding activities, showed GAP activity. for impaired was which Ndk, of mutant histidine-117 Rac/Cdc42 proteins (1 mg each) were incubated with with incubated were mg each) proteins Rac/Cdc42 (1 uoaiga. AC Ln 1 [a- 1, Lane (A–C) autoradiogram. p PEITLC on resolved eluted, were nucleotides Be bound min. 5 for 25°C at mixtures reaction separate in w thrice incubated and washed were beads min, 5 for protein that stimulated thatstimulated protein Thi form. GDP-bound the to Rho-GTPases GTP-bound of t H(37)Rv tuberculosis M. of supernatant in present d Nucleoside time first the for identified has IGIB TUBERCULOSIS KINASE OF DIPHOSPHATE NUCLEOSIDE MYCOBACTERIUM tuberculosis the reaction mechanism of Nucleotide diphosphate ki the nature essenti and the biochemical IMT explains ENZYMESAND OF PROTEINS BIOLOGY STRUCTURAL asbelow: shown is Ndk combination with hydantoinase mutants, which can be used to produce produce to used be can derivatives. which mutants, hydantoinase ver be will D-hydantoinase of structure The enzyme. f the inhibits mercury how showed D-hydantoinase of specific all specific to a in of variety spite ligands, of a lar they that showed proteins fold SH3-like looking of GDP formed when [a- when formed of GDP by quantified was formed GDP of Intensity (D) Ndk. GTPases (RhoA, RacI and Cdc42) and Lane 3, [a- 3, Lane and Cdc42) and RacI (RhoA, GTPases on the basis of the structure. Likewise the struct in vitro in 32 P]GTP was loaded either with Rho-GTPases alone or Rho-GTPasesor i alone with either loaded was P]GTP 32 GTP hydrolysis by members of Rho-GTPases. The Rho-GTPases. of members by hydrolysis GTP ]T. S–ehrs bas on GST-Rho/ bound beads GSH–Sepharose P]GTP. 32 ]T aoe Ln 2 [a- 2, Lane alone; P]GTP 19 ge ge sequence The variation. structure 32 iphosphate kinase (Ndk), to beto (Ndk), kinase iphosphate These results suggest that Ndk P]GTP plus Rho-GTPases andRho-GTPases plus P]GTP ia. GAP activity of Ndk with Ndk of activity GAP ia. hat stimulates the conversionthe stimulates hat al aminoacids responsible for responsible aminoacids al ads were washed twice and twice washed were ads nase (NdK) of y helpful in designing novel designing in helpful y ith or without Ndk (0.5 mg)(0.5 ithwithout or Ndk ae iia bnig sites binding similar have densitometer. The intensity The densitometer. 3 mCi of [a- mCi of 3 autophosphorylation andautophosphorylation lates and visualized by an by visualized and lates gulate Rho-GTPases, and Rho-GTPases, gulate nto o hydantoinase of unction ural analysis of similarly clue supernatant culture s eie aminoacid desired 32 ]T pu Rho- plus P]GTP 32 P]GTP at 25°C atP]GTP Mycobacterium n
S&T Contributions CSIR Annual Report 2004-05 A RAPID METHOD OF SEQUENCING LONG SYNTHETIC PEPTIDE
IGIB has developed a very simple and efficient method of sequencing of long peptides, using long polyglutamine stretches with and without interruptions, as model peptides, using MALDI-ToF in a linear mode. The method does not require any enzymatic or proteolytic digestions, and very long synthetic polyglutamine S&T Contributions S&T sequences can be sequenced efficiently, just by incremental variation of laser power. This method provides an alternative tool for validating long polyglutamine stretches, which are very often used as models for studying the structure and conformation of proteins associated with a number of neurodegenerative disorders.
SPAAN: A SOFTWARE FOR PREDICTION OF ADHESINS AND ADHESIN- LIKE PROTEINS USING NEURAL NETWORKS
The adhesion of microbial pathogens to host cells is mediated by adhesins. IGIB has employed 105 compositional properties and ANN to develop SPAAN, which predicts the probability of a protein being an adhesin (Pad). SPAAN had optimal sensitivity of 89% and specificity of 100% on a defined test set and could identify 97.4% of known adhesins at high Pad value from a wide range of bacteria. Further, SPAAN guided in improved annotation of several proteins as adhesins. Novel adhesins were identified in 17 pathogenic organisms causing diseases in humans and plants. In the Severe Acute Respiratory Syndrome (SARS) associated human corona virus, the spike glycoprotein and nsp's (nsp1, nsp5, nsp6 and nsp7) were identified with adhesin-like characteristics. These results offer new leads for rapid experimental testing.
LANGMUIR–BLODGETT FILM BASED BIOSENSOR
IGIB has developed a mono-enzyme amperometric biosensor for the estimation of galactose in milk and milk products. Galactose oxidase was immobilized with poly(3-hexyl thiophene)/stearic acid (P3HT/SA) on to indium tin-oxide (ITO) coated glass plates using Langmuir–Blodgett (LB) film deposition technique. This CSIR Annual Report 2004-05 P3HT/SA/GaO LB film on ITO-coated glass plate was used as working electrode with platinum as reference electrode for development of galactose biosensor. The biosensor shows the linearity 1–4 g/dl galactose. The electrode was found stable upto 45 °C and has a shelf life of more than 90 days.
GENES OF ASPERGILLUS FUMIGATUS
IGIB has generated 125 expressed sequence tags (ESTs) from 200 phage clones of a non-normalized cDNA library to identify genes of aspergillus fumigatus , a fungal pathogen, causes a spectrum of allergic and invasive disorders. Out of a novel 68 ESTs, 45 were assigned putative functions based on the sequence similarity. The
20 IHBT completed the sequencing nucleotide IHBT of an Indi PLANT VIRAL GENOME ORGANIZATION infections. for the development of antifungal drugs or that may or autoimmune reactions. Additional genes were iden identities of some of these genes suggest that they is responsible for responsible is thechiefly activation of Th1 ce with associated protein 150-kDa a that demonstrated AIDS, TB, against defending in cardinal is immunity immune response to evoke immunity esp cell-mediated a provides therefore study This response. cell Th1 was observed that this immunization strategy chiefl deliver antigen. The mice were immunized with antig a ofsource a as cells allogeneic using by response anti evoking of possibility the examined has IMTECH DELIVERY OF ANTIGEN CELLS IN ALLOGENEIC an antigen. of prediction the rapid for attractive very package integrat through addition value The command. single use thereafter and once only sequences their input a sing in been integrated havecomputer programs of availab commercially as user-friendly as considered scientif the by used heavily are and servers web of are availa methodsthese Though accuracy. high with have been developed by IMTECH. These allow a user t In the last 5 years, a large number of computer aid DESIGN A VAXIPRED: VA SUITE FOR PROGRAMS COMPUTER-AIDED OF sequenced. and and genes parts individual of the amplify wh genes, and 3’ end from 5’ CERVand genome using of primers by sequenced was CERV of genome The amplification. gen matrix Binding Inclusion protein, Poly Protein, Fa Transmission Aphid Protein, Movement viz. genome the by encoded genes the all of amplification Prim RT-PCR. by amplified were carnations perennial (MP protein movement and (CP) protein Coat reports. virus (CarMV). It was determined to be 4005 bp in length, 21 Carnation etched ring virus ring etched Carnation lls lls is and constitutively expressed ed prediction and design methods may be involved in pathogenesis djuvant and also as a vehicle to vehicle a as also and djuvant potential vaccine candidates in vaccine candidates potential y y elicited antigen specific CD4 rational approach for skewing for approach rational be of use in diagnosing fungal ich were ich were clonedsubsequently ic community, they were not were they community, ic le programs. A large number large A programs. le es and for complete genomecomplete for and es tified that are possible targets malaria, etc. It has also beenhas etc. It also malaria, le software, where can users where software, le the surface of macrophages of surface the an isolate an of isolate l te rgas hog a through programs the all en-pulsed en-pulsed allogeneic Itcells. ble to the public in the formthe in public to the ble o predict B or T cell epitopes gen-specific T cell immune cell T gen-specific with internal primers thatprimers internal with ecially ecially since cell-mediated ers were designed for the for designed were ers 2 bp longer than previous ) genes from annual and annual from genes ) ctor, DNA Binding, Coat Binding, DNA ctor, o mks hs software this makes ion amplifying the completethe amplifying Carnation mottle (CERV) CCINE +
S&T Contributions CSIR Annual Report 2004-05 on peritoneal but not splenic macrophages isolated from mice of different genetic backgrounds: Balb/c, C57BL/6 and C3He. However, it was expressed not only on peritoneal but also on splenic macrophages of non-obese diabetic (NOD) mice. Expression on splenic macrophages was significantly induced by culture with lipopolysaccharide (LPS), interferon (IFN)-gamma and granulocyte-macrophage
S&T Contributions S&T colony stimulating factor (GM-CSF) and cross-linking of B7-2, CD40 and ICAM-1. In contrast, the expression was inhibited by interleukin (IL)-10.
AGNI
NBRI has developed an excellent hybrid from a cross between cultivar ‘Charm’ and cultivar ‘Pink Pearl’. This hybrid produces 1-2 scapes (50.0 cm tall) bearing 2- 4 horizontal flowers during March-April and lasts for a week. The flowers are large in size (19.0 cm across), flat faced, fully open, showy and attractive red (47A/F-1) colour and no streaks present on ground colour of the petal. The throat is yellowish green in colour (150 C/F-3). The petal texture and bloom quality are very good. The plant is evergreen and produces dark green foliage. This hybrid does not produce seeds but it can be used freely as a male parent.
‘Agni’ - A new hybrid of Hippeastrum CSIR Annual Report 2004-05 SAINT BERNARD’S LILY
NBRI has introduced Chlorophytum bichetii (Karrer) Backer popularly known as ‘Saint Bernard’s Lily’ belonging to family Liliaceae with handsome foliage. The plant is native to Gabon (Tropical West Africa) and has been performing well at Lucknow under sub-tropical climatic conditions. It is a dwarf herbaceous plant with fleshy roots growing to 20 cm high forming bushy tufts of linear-lanceolate leaves 10-20 cm long and 0.85-1.66 cm wide, thin-leathery, fresh-green with yellowish white stripes particularly along margin, distinctly petioled. The flower stalks, distinctly shorter than the foliage, are slender, lax and usually branchless, flowers white rather larger than those of other Chlorophytum under cultivation, pedicels jointed below middle.
22 biopesticide by using solid state fermentation. The water. water. The solid is rich in phenolics stable colou material). raw the in 3% (yield solid hygroscopic arboreum water colouring non hygroscopic, highly removing by and convenient simple aprocess has developed IHBT EXTRACT OF mature plants of condition known physiological age ensured be field the in seedlings the of performance BI a dvlpd tcnlg fr as production mass for technology a developed has NBRI TECHNOLOGY OF PLANT GROWTH DEVELOPMENT PROMOTING growth promoting mustard microorganism sunflower, ( maize, chickpea vine, betel viz. e of diseases borne soil control to found been have vivo both propagation massattempting before ensured was fi the in seedlings the of selection Prior genesis. secr of amylase analysis biochemical and techniques sunlight for 4 hr. and to acidic medium.to acidic and hr. 4 for sunlight of of has IHBT protocol standardized for somatic embryo g BAMBOO MICROPROPAGATION seedfor bio-fungicide and growth as enhancer plant f tolerance growth, phosphatesolubilize even under abiotic stress cond plant promote fungi, the pathogenic have which developed also were products, based edoaau hamiltonii Dendrocalamus as well as through tissue culture. The selections selections The culture. tissue through as well as flowers using polymeric resin to obtain brick-red RHODODENDRON ARBOREUM RHODODENDRON Chlorophytum bichetii (Karrer) Backer taig opoeei eet uig histological using events morphogenetic tracing , Pseudomonas 23 and r. r. It was stable up to 150 eld grown plants of of plants grown eld
Trichoderma- It is readily soluble in alcohol/ in soluble readily is It Bacillus itions. itions. The products are useful conomically important cropsimportant conomically etion during embryosomatic during etion , soil, and foliar applications.foliar and soil, , ad h poaain from propagation the and s tter performance in the field. gails t. oe plant Novel etc. gladiolus , enesis enesis from mature explants to extract and colourtoenrich and extract were based on the growth the on based were through nodal explants explants nodal through soluble portion from from portion soluble blt t cnrl phyto- control to ability r boi srse, and stresses, abiotic or colour free flowing non- and TRICHODERMA of of based bio-pesticides Trichoderma Trichoderma Trichoderma D. hamiltonii D. 0 C, C, under strains) based R. in
S&T Contributions CSIR Annual Report 2004-05 SOFTENING INSECT CELL WALLS FOR KILLER FUNGI
NCL have uncovered the role of certain enzymes in “softening” the cell wall of pests. These enzymes could greatly enhance the effectiveness of a certain class of pesticides called myco-pesticides. Myco-pesticides use fungi to kill pests. The mechanism by which fungal pesticides (or myco-pesticides) act is: the fungi produce S&T Contributions S&T dry spores that stick to the body of the insect. After attachment, the fungal spores produce filaments called hyphae that penetrate the body of the insect. These filaments then multiply and poison the pest. Typically, the fungal filaments enter the insect body via wounds or through joints between segments of the insect body or via its sense organs. The main barrier in the penetration process is the hard skin (cuticle) of the insect that is composed of a hard polymer called chitin. Therefore, if the insect cuticle can be softened, the pest can be killed faster by fungal filaments. It has been demonstrated that certain enzymes in conjunction with these fungi can form a highly effective integrated formulation to kill pests. For example, in lab tests, use of the enzyme with Metarhizium anisopliae , a fungus used against a pest called the gram pod borer ( Helicoverpa armigera ) took less than three days to eliminate the pest.
Schematic of softening of insect wall 1 PEST RESISTANT PLANTS
CSIR Annual Report 2004-05 NCL has demonstrated the effectiveness of a novel approach to thwart pests by developing pest-resistant variety of chickpea. To defend themselves against insect attack, plants synthesize a wide range of molecules. Of these, the Proteinase Inhibitors (PI) block digestive capabilities of the insect and, are detrimental to the growth, development and reproductive potential of insects. These molecules are part of the plant’s natural defense system. The proteinase inhibitor synthesized by a plant might not be effective against all insects. NCL has found that the Gram Pod borer disarms the host plant’s natural defense mechanism by inactivating proteinase inhibitors and, then feeds on them. Several other plants were screened, which were resistant to the Pod borer and identified their Pls. The study revealed that when Pls from winged bean, bitter gourd, capsicum, potato and groundnut were fed to the Pod borer, its growth and, egg-laying/hatching abilities were
24 RRL-Jorhat has developed a process to produce high high produce process uses an strain indigenous bacterial to process a reaction condition mild under acid hydroxynicotinic developed has RRL-Jorhat 6-HYDROXYNICOTINIC ACID OF BIOTRANSFORMATION NICOTINIC ACID TO pulp. paper of biobleaching in activity effl thermostable, possessing isolate fungal marine applicati potential the showing report first the is uranosidase, which could act synergistically with x beta-xy of activities moderate showed also filtrate ciiy Tecue nyefo NOC slt (3 isolate NIOCC from enzyme crude The habitats activity. marine from obtained were isolates fungal NIO has screened obligate and facultative marine fu PULP PAPER OF BIOBLEACHING FROM FOR MARINE XYLANASES FUNGI USE INPOTENTIAL Th yeast. b Pod the against activity effective show organisms and bacteria to transferred successfully th for genes The responsible retarded. dramatically was detected at 50°C, with a second peak of activit of peak second a with 50°C, at detected was activity at xylanase WhenpH assaye 3.5 pH 8.5. and in consumption of The cu bleaching. chlorine during treatment at sugarcane 55°C, resulting of in a bleaching decrease of about ten k bring could xylanase, proper unique and effluents-free activity, xylanase 25 Pseudomonas appa numbers and a 30% reduction on of crude culture filtrate of aof filtrate culture crude of on ngi for xylanase activity. Several losidase and alpha-L-arabinof- and losidase ylanase ylanase in attacking xylan. This ties containing 580 U l sup(-1) l U 580 containing ties ese PIs have been isolated ese andisolated PIs have been orer. d d at optimum 3.5, activitypH y at 90 at y lture lture filtrate peaks showed of s with a yield of 90-95%. The of 90-95%. yield awith s et-re laie xylanase alkaline uents-free seglu nigerAspergillus Ps yteie b these by synthesized PIs e aas pl b a 0 min 60 a by pulp bagasse hwd laie xylanase alkaline showed sp. for RLJ12N producing o C. The crude culture crude The C. ocnrto o 6- of concentration , ih high with ),
S&T Contributions CSIR Annual Report 2004-05 100-120g/l of 6-hydroxynicotinic acid by reacting nicotinic acid with resting cells of the organism in aqueous medium at pH 6.5 - 8.5 and at 25-350C over a reaction period of 17-24 h. The product yield is high (90-95%) due to high specificity of the nicotinic acid hydrolyase present in the strain RLJ12N.
S&T Contributions S&T 1.2.3 Human Resource Development
CCMB
• Hands on training course on “Chromosomal & Molecular Diagnostics”
• A Three-day Symposium on “Molecular medicine and health”
• An International Conference on Translational Research (B2B-2K5) for “Cancer and Other diseases”
• Hands on training course on “Advanced Microscopy and Image Analyses”
• International EMBO workshop on “Cell Interactions in Development and Diseases”
• International workshop on “Bioinformatics”
• Summer training: CCMB conducts summer training programme for M.Sc. students every year in the month of May-June. During the year, 28 M.Sc. students were chosen on a national basis for hands on research training
IGIB
• An innovative course-work program in integrative biology for Ph.D. students has been launched. The program is specially designed to encourage young minds to thinking vacuum and come up with integrative methods of approaching contemporary challenging problems in biology. The broad areas that would be covered in this course are biological information flow, time and space in CSIR Annual Report 2004-05 biological systems, system biology approach to biomaterials and organ systems, host-pathogen interactions, microbial community structure and dynamics and bio-tools theory and practice.
IHBT
• Training on: Medicinal and aromatic plants; Bioresource awareness; Production of disease free planting material; IPR
• CSIR Programme on Youth for Leadership in Science: Thirty three participants attended the programme. The students were exposed to R&D activities and research facilities of the Institute.
26 • • • • • • • • • IMTECH • RRL-JORHAT NBRI Manager and Govt.Manager and officials. Mushroom to various sections of society viz. farmer & Medicinal of technologies cultivation on Training the in participated Council Technology and Science and (MASTEC) Council and Technology Science Manipur teach students, comprising participants nine Thirty was held for school students of Assam and Manipur d Motiv Science A 5-day Programme: Motivation Science programme.the in part tookschools various from ( Science in Leadership Youthon for CSIRProgramme hav etc. mitigation hazard chemistry, biodiversity, superstition and science health, general practices, t of series a on house open like programmes Various Year oforganiz was Scientific (YSA-2004) Awareness Schem Training Apprenticeship and Graduate Training Tra India of Govt. the conducting is laboratory The wastes. kitchen of use gardenin homeabout imparted been also has Training places. various at organised were crafts ofon programmes dehydration training Six two-day on Workshop National Biomolecules” of Purification and A two week short-term training course on “Trends in Summer & Programme Training Winter for M.Sc. (Biote Proteins ” “ okn ad oeua Smltos of Simulations Molecular and Docking 27 , child health care, health child , s, s, men and women, Bank e been organized. been e Fermentation, Recovery ers and officials from officials and ers Apprenticeship de Aromatic Plants andPlants Aromatic programme. uring uring 12-16 July, 2004. ed ed theby laboratory. opics of agricultureof opics flowers floraland flowers CPYLS): 57 toppers 57 CPYLS): g and sustainable and g ation Programmeation chnology) chnology) students es. Tripura StateTripura
S&T Contributions CSIR Annual Report 2004-05 1.2.4 Recognition & Awards
“The Great Son of the Soil” award by All Dr. Lalji Singh, CCMB India Conference of Intellectuals (AICOI) Honorary D.Sc. from Banaras Hindu
S&T Contributions S&T University
INSA Medal for Young Scientist Ms. Pallavi Kshetrapal CCMB Fellow of Indian Academy of Sciences, Dr. D.P. Kasbekar, CCMB Bangalore Shanti Swarup Bhatnagar Prize in Biological Dr. R. V. Sonti, CCMB Sciences- 2004
Fellow of Indian National Science Academy Prof. S. Roy, IICB
Fellow of Indian National Science Academy Prof. A. Dutta, IICB
Chairman of West Bengal Science & Dr. H.K. Majumdar, IICB Technology Council
Elected as Council Member of Human Prof. S. K. Brahmachari, IGIB Genome Organization (HUGO) for a period of 3 years.
CSIR Young Scientist Award in Biological Dr. D. Dash, IGIB Sciences 2004
“Ranbaxy Award” for the year 2003 Dr. G. Sahni, IMTECH
Scientific Advisory Committee of M/s Dr. Amit Ghosh, IMTECH Nagarjuna Fertilizers & Chemicals, Ltd. Hyderabad
CSIR Annual Report 2004-05 Fellow of Indian National Science Academy Drs. G.P.S. Raghava & J.N. Agrewala, IMTECH
Guha Research Conference Drs. P. Guptasarma & Jagmohan Singh, IMTECH
B.P. Poddar Memorial Award (2003-04) for Dr. N. Saika, RRL-Jorhat environmental improvement / awareness
AMI Louis Pasteur Award for the year 2004 Dr. T. C. Bora, RRL-Jorhat for outstanding research contribution
28 Mesoporous materials/ Supported Materials & Organic & Materials Supported materials/ Mesoporous Fine specialty chemicals: specialty Fine removal. (VOC) carbon organic volatile for tested template as materials mesoporous based silica using materials, were developed. Carbon based mesoporous S and MCM-48 MCM-41, stable for protocols synthesis PROGRESS: cat in evaluation and particles Nano and tubes Nano with high yield using a variety of solid catalysts solid of variety a using yield high with a with carbonates cyclic the of transesterification I. DEVELOPMENT OF CATALYSIS AND CATALYSTSOF AND CATALYSIS DEVELOPMENT I. Progress made under ProjectsNetwork 1.3.1 b are presented non-network projects network and in chemical and characterized catalysts, by high level of innovativeness. Some agrochemicals, of areas the ch the with credibility high enjoy to come has CSIR TECHNOLOGY & SCIENCE CHEMICAL 1.3 SGPGIMA, Lucknow Dr. P. Pushpangadan, NBRI P. Pushpangadan, Dr. Sciences (FNAAS) Agricultural of Academy Dr. C.S. National of the N Fellow 2004Commercialization Award P. Push Dr. and Development Process, Product, Biotech Science Academy Environmental National of Award-2004 Govt. of Fellowship India DBT Population’, Rural SC/STand for based ‘Biotechnology on Force Task Reconstituted Member, SGPGIMA, Lucknow atCentre (VMI) Initiative Medicine Vedic Formation for of Board Advisory Expert, CO The project envisages development of novel mesoporo 2 tlzto- poes o snhss f iehl c dimethyl of synthesis for process A utilization- 29 liphatic alcohols was carried out carried was alcohols liphatic including alkali doped alkaline doped alkali including of the significant achievements emical industry especially in especially industry emical alytic oxidations. alytic elow: . These materials are being are materials These . materials materials were synthesized intermediates-subsectors us materials that includes functionalizations A1 tp mesoporous type BA-15 autiyal, autiyal, NBRI pangadan, NBRIpangadan, roae by arbonates : : The
S&T Contributions CSIR Annual Report 2004-05 earth metal oxides like MgO, various tungsten oxides, nitrogen containing ligand anchored on mesoporous materials.
Chiral auxiliaries and chiral catalysis: Ruthenium-based homogeneous catalyst was combined with the solid silicate supports such as mesoporous MCM-41 and MCM-48 materials, to produce a new and efficient heterogeneous asymmetric S&T Contributions S&T hydrogenation catalyst. NCL has demonstrated that the heterogeneous catalyst exhibits high conversion (>90%) and high selectivity (up to 99%) towards a particular enantiomer in the hydrogenation of a variety of prochiral ketones to chiral alcohols. The efficiency of the new catalyst in terms of activity and enantioselectivity is very high compared to previously reported catalysts in the literature. The stability and reusability of the heterogeneous catalyst make it a potential candidate for utilization in industrial asymmetric hydrogenation reactions.
DeNOx Catalyst: Various rhenium-oxide entrapped zeolite catalysts were prepared by pre and post synthesis modifications of zeolites to achieve better support metal interactions to enhance the stability of metal active sites at reaction conditions employed. Synthesis of zeolites was performed in stainless steel autoclave covered with Teflon and the structure of the material was confirmed by XRD. Among the various zeolites, H-ZSM-5 exhibits suitable pore geometry with pore diameter of around 5.5 A for the formation of rhenium oxide nano-clusters that are anchored to zeolite walls by long range and short range chemical bonds.
ZSM - 5 pore channels and across sectional view
CSIR Annual Report 2004-05 II. DEVELOPING GREEN TECHNOLOGIES FOR ORGANIC CHEMICALS
The project targets to develop Green processes for bioactives from medicinal plants value-added organic chemicals from biomass and agro industrial wastes, alkylation and oxidation of aromatic compounds, fluoroorganics by chemical/electrochemical methods and novel mesoporous nanomaterials.
PROGRESS:
Isopropylation of benzene to 1,3-diisopropylbenzene using alkylhalide under solvent free conditions: Synthesis, characterization and catalytic screening of different catalysts with different zeolite structures for the isopropylation of benzene
30 amongst Fe, Ga, Al, Zn, Cu and Zn, CuCe.and Ga, Al, amongst Fe, suitab most as identified were Ga and Fe screening, chloride and isopropyl bromide as alkylating agent free solvent and phase liquid temperature low under Isolated Purified sample of sample Purified Isolated for developed was procedure analytical HPLC rapid A PROGRESS: etc.dyes natural functional new and nov e.g country the for important strategically and It is envisaged to develop new generation technolog AND PROCESSES CHEMICALS COMPETITIVE GLOBALLY III. easi very devices based MEM with integrated be also cir electronic complicated require and life working room temperature. Typical sensor geometry is indica is geometry sensor Typical temperature. room ppm obtained as standard calibration ampoule) showe substrates (PET) pattern with and interdigited test tec various co gold by on coated when polymers These modification. characterized were These doped. were mainly as the main conducting polymer in which the g monoxide carbon for sensitivity their increase to org based iron and with ferrocene modified suitably ual caig ad deie, ucinl polymers functional adhesives, and coatings curable nano and hybrids Organic-Inorganic as such polymers f materials raw sustainable use to aims project The MATERIALS POLYMERIC OF NOVEL DEVELOPMENT IV. Conducting polymers based MEMS for sensors Such sensors can replace the electrochemical-based PRODUCTS artemisinin from 31 A.annua A.annua :
Conducting polymers have been ed ed for sensitivity to CO gas (300 was achieved. Based on detailed as. Polypyrole (PPY) was used was (PPY) Polypyrole as. or the preparation of specialtyof preparation the or el bioactives, alternative fuels, alternative bioactives, el cuitry for detection. These can These detection. for cuitry ies ies for high demand chemicals iron iron based organic complexes ano-metallic complexes soas complexes ano-metallic . ted below ted le ion-exchangeable cations ion-exchangeable le ly. conditions using isopropyl using conditions sensors, sensors, which have limited d d tremendous sensitivity at ated flexible polyester film polyester flexible ated opsts UV/E-beam composites, VCR and VLB analysis. VLB and VCR o cia separations, chiral for nqe t cnim the confirm to hniques
S&T Contributions CSIR Annual Report 2004-05 Specialty Polymers for petroleum industry, and Specialty polymers from renewable resources.
PROGRESS:
S&T Contributions S&T UV/E beam curable coating: Development of G & I line photoresist : NCL has standardised a process for facile synthesis of terpolymer of poly(hydroxy styrene). Formulation based on this base resin was tested which could resolve 1 micron geometry. The material has potential for I line and deep UV. Photoresist of 1.4 mm thickness with good sensitivity and reproducibility was established. It is also demonstrated that `high ortho ' novolac copolymers with optimum m- and p-cresol content and optimum base solubility has yielded a well-defined line latitudes and excellent performance against conventional lithographic steps like etching, lift-off and others. The photoresist is currently under test at semi commercial level at SSPL, New Delhi.
(Poly hydroxy styrene) based novel terpolymer photoresist: Opening of 1 - micron geometry CSIR Annual Report 2004-05
Barrier of 0.5 micron geometry was crossed by ortho novolacs resin based photoresist formulation
UNCTIONAL POLYMERS FOR CHIRAL SEPARATIONS:
Tailored beaded hydrophobic polymer matrices for the immobilisation have been developed as polymeric supports. Macroporous functionalized copolymer networked with pendent epoxy groups were synthesized with relatively high
32 1.3.2 Scientific Scientific achievements under prog non-network 1.3.2 moulded, shapes.various into injection moulded be can compositions These aid. has been achieved by introducing a dispersing agent processabili the Also, friendly material. this of synthesis environmentally non-corrosive, gives which non-aci by route of polyaniline A synthesis for new INDUSTRY ELECTRONICS FOR APPLICATIONS POLYMERS CONDUCTING ELECTROACTIVE/ ligands. affinity as serve to oils was further altered by the covalent incorporation o permane diluents (porogens). In addition, modified for lipase immobi a was structure porous have The to molecules. enzyme monomers t and trap to essential structure, divinyl (macroreticular) of concentration When this molecularly imprinted polymer is mixed wi mixed is polymer imprinted molecularly this When cholesterol and the monomers are precisely arranged is polymer the Thus, polymer. imprinted molecularly th monomers) molecules by (called is and surrounded involves which Chol cholesterol. of shape exact the technique, with imprinted imprinting" "molecular by previously reported best of 17 mg cholesterol. The v of gram per cholesterol cholesterol of mg 45 hold can remove polymers that polymers designed has NCL CHOLESTEROL REMOVE TO POLYMERS are: achievements significant the of Some also. Apart network from projects CSIR laboratories are w Spherical Spherical porous epoxy polymer beads synthesized fo 33 r immobilization r of immobilization PGA and lipases ty of the conducting polyaniline conducting the of ty o covalently anchor large sized large anchor covalently o special special polymers were prepared f hydrophobic tails, unsaturated lization lization the micro-environment , , which also acts as a processing dic achievedmethod dic been has esterol is used as a "template"a as used is esterol so as to recognize cholesterol. orking orking non-network in mode the molecule surpassing the surpassing molecule the at are linked to up theatform linked are fixed into the shape of theof shape the into fixed xrdd r compression or extruded th body fluid containing fluid body th ehd o large-scale for method rammes y noprtn inert incorporating by rain f polymers of creation r efciey these - effectively ery t macroporous nt IN
S&T Contributions CSIR Annual Report 2004-05 cholesterol, the cholesterol "docks" perfectly into the cavity in the polymer and is removed along with the polymer. S&T Contributions S&T
ULTRA PURE SALT
CSMCRI has developed a cost effective, innovative method for the production of high quality industrial grade solar salt with improved whiteness. The process is based on changing the salt-crystal morphology by clarification of the feed brine using physico-chemical methods. Microscopic studies have confirmed that the salt crystals are compact with less defects and minimum entrapped impurities. The salt crystals are larger in dimension as compared to salt harvested by conventional methods. The final product has specifications as Ca=0.07-0.11%; Mg=0.05-0.07%
and SO 4=0.15-0.2%. The whiteness index of the harvested salt is measured as 86-88 against 78-83 for the normal salt produced through the conventional method. The process is simple and can be implemented in any salt works.
CSIR Annual Report 2004-05 NaCl TOLERANCE IN CALLUS CULTURES OF SUAEDA NUDIFLORA Moq
CSMCRI has studied salt tolerance in the cultures of Suaeda nudiflora Moq. A dicotyledonous succulent halophyte. Growth was significantly inhibited at 50, 100, 150 and 200 mM NaCl. Inorganic ions and proline accumulated in response to salinity. Ion accumulation pattern reflected the utilization of Na + as an osmoticum. Na +/K + ratio rose steadily as a function of external NaCl concentration. Salt stress enhanced the activity of peroxides, whereas it decreased activities of super oxide dismutase and catalase. This would help in identification of genes involved in salt tolerance and improvements of plants species for salt resistance.
34 that will enable the production of PBI membranes fo membranes PBI of production the enable will that rep processes These conditions. safer milder, under poss it make that catalysts novel use processes The Both the processes yield highly pure DAB (100 per c DCB) involves a three-step process with a novel cat meth second The catalyst. efficient highly novel, a process uses a non-carcinogenic raw material (nitro availabl commercially not is PBI prepare to used is their mechanical strength at high temperatures. How they as applications (PEM) membrane exchange Proton membranes PBI that recognized been has It fuel. for high- the monomer that(DAB) to obtain polybenza used is prepare to processes new two developed has NCL MEMBRANE CELL FUEL FOR PROCESSES NEW membrane. application chlor-alkali and cell fuel for suitable membranes were comparable with Nafion whi membrane, membrane. Furthermore, physicochemical and electroc organic-ino have to order in required is properties that a definite compromise between the silica conte and physicochemic mechanical stability, and thermal morphology their for characterized extensively were sulfonic groups acid were introduced at the inorgan ae o plvnl alcohol/SiO polyvinyl on based m hybrid Organic-inorganic medium. aqueous in route proton-exchange or exchange ion resistant chemical prepara the for method novel a CSMCRIdeveloped has CELL FOR FUEL MEMBRANE EXCHANGE CATION- STABLE THERMALLY activity. antioxidant powerful a study Pharmacological hair. of luster and texture non-sticky and anti-fungal, non-allergenic, toxic, de thus dye The eco-friendly. and safe perfectly is used in coloring hair black. The method of obtainin shining ebony black to brown and pinkish red. The m range o a hasa method NBRI developed preparing for HAIR DYEECO-FRIENDLY 2 udr cdc n bsc odtos i which in conditions, basic and acidic under , 35 alyst called titanium superoxide. s as a substitute for the Nafionthe for substitute a as s ent purity) with no by-products. nt and membrane ion-exchange to skin. The dye enhances, the enhances, dye The skin. to g g the dyes from plant materials od (from dichlorobenzidine or dichlorobenzidine (from od -bromoacetamide or NBA) and rganic hybrid cation exchange cation hybrid rganic e in large quantities. The first The quantities. large in e ible to carry out the reactions the out carry to ible ic These segment. membranes lso revealed that the dye has dye the that revealed lso eoe i nnicig non- non-itching, is veloped , intermolecular interactions, intermolecular , ever, ever, the monomer thatDAB r fuel cell applications. cell fuel r ixture ixture of dyes derived can be resent a significant advance significant a resent al properties. It properties. concludedis al membranes by eco-friendly by membranes r epcal sial for suitable especially are midazole (PBI) membranes (PBI) midazole f safe herbal hair dyes dyes with hair f herbal safe hemical hemical properties of these tion of thermal stable and stable thermal tion of embranes were prepared were embranes ont erd r lose or degrade not do uiy diaminobenzide purity ch suggest that they are
S&T Contributions CSIR Annual Report 2004-05 TUNABLE SINGLE ELECTRON TRANSPORT IN NANOPARTICLE ASSEMBLY
An easy method has been developed to organize gold-MPCs at a fixed distance on SAM modified gold substrate, where the distance could be controlled by changing the length of the SAM forming molecule. The I-V measurements have done in air at S&T Contributions S&T room temperature by using aforesaid mercury based junction. These results help to understand the electronic behavior of nanoparticles based molecular circuits especially useful for constructing future electronic devices.
MONOLAYER CATHODES FOR LITHIUM BATTERIES
NCL has demonstrated that a cathode prepared from a single layer of molecules can be used for high-energy rechargeable lithium batteries. It could reduce the
CSIR Annual Report 2004-05 weight of the battery drastically. For the first time a self-assembled monolayer of an organic molecule (a disulphide) has been used to prepare cathodes. Self- assembled monolayers (SAMs) are closely packed arrays of organic molecules, can be easily prepared and are very stable. SAM is prepared on a metal using a disulphide, an organic molecule with sticky sulphur atoms attached on each end. Disulphide is stuck on gold to create a single well-ordered monolayer and this forms the cathode. The disulphide molecule allows lithium ions in solution to effectively hook-up with the cathode and establishes a flow of current through the external circuit. The SAM coated gold was used along with a lithium electrode to prepare a lithium battery that gave an open circuit voltage of 2.9 V.
36 petroleum and synthetics, produce lower emissions lubr o 2-stroke based on biode completely be almost petroleum, dependence oil vegetable of Use end-users. h nw rdcs de t due products, new the (VOC) and particulates and offer new employment ave petroleum or synthetic oils and offers significant significant offers and oils synthetic or petroleum en 2-stroke agricultural-based This products. based performance same least at or better offers that oil vegetabl non-edible biodegradable developed has IIP OIL VEGETABLE NON-EDIBLE 2-STROKE BASED ENGINE OILS diesel diesel (ULSD). to be a complementary process to traditional HDS fo desulphu oxidative Therefore, ppm. 10 below content extraction by / ultra l adsorption yielding thereby oxidized easily be can (HDS), hydrodesulphurization 4,6-dimethyld which extremely are difficul derivatives, alkylated like compounds sulphur refractory the a is process The adsorption. or solvent polar with subsequ and polarity their increase to sulphones to 4,6-dimethyldib and DMDBT). In this process the sulphur (4-MDBT) compounds prese method methyldibenzothiophene desulphurization oxidative developed has IIP OXIDATIVE DESULPHURIZATION OF DIESEL wear. engine and temperatures o t ipoe lbiiy wl rdc egn operatin engine reduce will lubricity, improved its 37 ow sulphur diesel ow diesel with sulphur sulphur benefits t benefits t in to deephydrodesulphurize as petroleum or synthetic oil synthetic or petroleum as dvantageous in the sense thatsense the in dvantageous gine oil is less expensive than expensive less is oil gine r r producing ultra low sulphur f ently removed by extraction by removed ently
Volatile Organic Compound nt in diesel are first oxidized to sulphones and removed and sulphones to nues in rural sector. Further e oil based 2-stroke Engine 2-stroke based oil e rization has great potential great has rization gradable, less volatile thanless volatile gradable, cns s on t reduce to going is icants bztipee n its and ibezothiophene o te eoa o 4- of removal the for o nohohe (4,6- enzothiophne environment and t and environment g o
S&T Contributions CSIR Annual Report 2004-05 IMPROVED SOAKER VISBREAKING TECHNOLOGY
IIP has developed an indigenous technology on soaker visbreaker with internals. The main advantages of the improved soaker includes better temperature profile, increased conversions or reduction in beater duties for same conversion level, increased fuel oil stability as a result of uniformity in process temperature and S&T Contributions S&T feed distribution and enhanced run lengths due to prevention of undesirable side reactions leading to coke formation. The developed internals are easy to de-coke and require less effort to clean during shut down operation. The incorporation of internals can be performed through the revamping of the existing soaker.
Soaker Reactor With Internals
BIOSYNTHESIS OF GOLD NANOPRISMS FROM LEMONGRASS
NCL has demonstrated biological synthesis of triangular gold nanoprisms. The size and shape-dependent properties of metal nanoparticles are known to have
CSIR Annual Report 2004-05 important applications in catalysis (conversion of carbon monoxide to carbon dioxide), biosensing (novel labels for DNA diagnostics), and high-density recording media. Despite its importance, controlling the shape has so far yielded only limited success. Specific chemicals such as polypeptides secreted by the bacteria ( Escherichia coli ) have been shown to induce the growth of flat, triangular gold nanocrystals at 4% yield relative to the total nanoparticle formation. Large amounts of triangular gold nanoprisms by a single-step, room-temperature reduction of gold salt solution has been synthesized biologically by the extract of the plant, lemongrass ( Cymbopogon flexuosus ). The percentage of gold nanotriangles in the reaction medium has also enhanced up to 95% of the nanoparticle population by repeated centrifugation.
38 whereas the concentration required by monomer is ab is monomer by required concentration the whereas eff inhibition the offered have concentration 10ppm inhibitor for iron in 1M HCl. It aminop has been found th poly the for evaluated and synthesized been have diamine polyaniline, like polymeramines soluble o corrosion of control for anilines substituted and mo as such inhibitors corrosion employed has CECRI MEDIA INHIBITORS AMINES CORROSION FOR AS IRON IN POLYMER purpose.this for erected structure model term performance of this innovative technology has to on strapped just are backfill polymer conductive str in anodes Sacrificial system. the of monitoring satisfacto for needed Maintenance at reference embedded c electrodes free reinforcements steel embedded mi the ensuring and medium concrete resistance high fill is capable of effectively distributing the cur the distributing effectively of capable is fill first is which fill (PCPS) back polymer conductive new, simple and cost effective sacrificial protecti cathodic is labo quite also but expensive now, only not is technique till technique, foolproof only the co reinforced damaged salt in control corrosion For STRUCTURES AND BRIDGES CONCRETE REINFORCED FOR BELTS CONTROL CORROSION NEW Gold nanoprisms from lemongrass 39 rent from a strip anode across theacross anode strip a from rent on system based on a novel proton at the polymer amines of less than ip form along with the protonthe with along form ip of this kind in India. This back This India. in kind this of rious. CECRI has developed a developed has CECRI rious. io i ai mda Water- media. acid in iron f been been evaluated on a prototype ncrete bridges and structures, and bridges ncrete ectiveness of more than 90%than more of ectiveness ritical ritical locations enable easier the concrete surface. Long- surface. concrete the rtcin Hwvr this However, protection. ir effectiveness as corrosionas effectiveness ir out 1000 ppm. out1000 nomer amines like aniline like amines nomer iu oeta sit on shift potential nimum y ahdc protection. cathodic ry eo, polyphenylene henol, ACID
S&T Contributions CSIR Annual Report 2004-05 ELECTRO-REFINING OF ALUMINIUM METAL
A new novel two-layer electro refining process has been developed by CECRI where the alloying of the impure metal with copper is completely avoided. The anode and cathode metals are separated by a thin refractory partition. The anode metal (impure aluminium metal) and the cathode metal (super pure aluminium metal) S&T Contributions S&T
are allowed to float over the surface of the electrolyte containing BaCl 2, AlF 3 and NaF. Two layer electro refining cells up to 1000 Ao capacity were operated and various operating parameters have been optimised.
POLYSACCHARIDE BASED SOFT CAPSULES
CSMCRI has developed a method for preparation of polysaccharide based soft capsules from inexpensive kappa carrageenan as a seaweed polysaccharide in preparation of tough, biodegradable films. The films can be recycled and reprocessed if required. Incorporating polyvinyl alcohol that lends toughness and clarity can enhance the performance of the films. It is possible to store solvents and oils in the pouches, made of polysaccharide.
NOVEL CLASS OF PYRIDOSTEROIDS
A solid phase base catalyzed condensation of steroidal ß-formyl enamides with nitromethane under microwave irradiation led RRL-Jorhat to develop a new strategy for the one-pot preparation of a novel class of pyridosteroids via Henry reaction. The hitherto known applications of Henry reaction have been developed using sonication, high pressure reaction, heterogeneous catalyst and polymer support. This reaction has attracted enormous attention as one of the valuable fundamental synthetic strategies for construction of carbon-carbon bonds.
1.3.3 Human Resource Development
CSIR Annual Report 2004-05 CECRI
• CECRI conducted various training programmes related to corrosion of steel, Recovery of silver from photographic solution, Paints for corrosion protection, “Industrial Metal Finishing and demonstration, Plating of precious metals, Trouble shooting in Electroplating and metal finishing, Surface coating by PVD, CVD and Surface analysis etc.
CSMCRI
• CSMRI conducted regular training programs for the benefit of marginal salt producers of the country and provide technical assistance for good quality salt
40 NCL 1.3.4 Recognition 1.3.4 & Recognition Awards • Baroda for leadership for Baroda Baroda Sun (2005) Award Bank by of Scientific Bodies (India and Abroad) Election to Prestigious Academies and Engineering: Honorary Doctorates in Science & industry. train to and enterprise viable a as culture tissue educa the encourage to was programme the of aim The NCL conducted a training programme of 12 days durat industries. technical personnel and executive officials from va institute The works. salt own their in manufacture Society of India (2004); Research Materials President, Science Academy (2005); National Indian President, (2005);Kolkata Science, of Cultivation Associationthe for Indian Fellow, Academy of Sciences, USA (2005); National Associate, US Foreign General, CSIR (2004) (WB) Kalyani Kalyani, of University (2004); Faizabad & Technology, University Dev Narendra of Agriculture Pantnagar (2004); Technology, & Agriculture of University Pant Ballabh Govind (2005); RohtakMaharishi University, Dayanand Dr. R.A. Mashelk (2005); Guru Nanak Dev Amritsar University, 41 manpower for tissue culturetissue for manpower rious rious salt & marine chemical imparted training also to also training imparted ion on micropropagation. ted people to take up take to people ted ar, ar, FRS, Director
S&T Contributions CSIR Annual Report 2004-05 Star of Asia Award (2005) of Business Week (USA) Maharashtra Bhushan Award (2005) by Govt. of Maharashtra for contributions to Science & Technology S&T Contributions S&T Honorary Professor, Banaras Hindu University (2005) NACE meritorious contribution award Dr. N. Palaniswamy, CECRI Mascot National Award (Awarded by the Dr.G. Venkatachari, CECRI Electrochemical Society of India, Bangalore) CSIR Technology Award 2004 in S/shri V.J.Shah; (Ms) S.V.Joshi; “Chemical Technology” for J.J. Trivedi; C.V. Devmurari; A. P. Development of High Flux Thin Film Rao; N. Pathak; P.A. Patel; A.A. Composite Reverse Osmosis Patel; N.K. Waghani; T.B. Gohil; Membranes Technology and its K.J. Anjara; K. Eswaran and P.K. Applications for Water Desalination and Ghosh, CSMCRI Purification” CSIR Young Scientist award 2004 in Dr. P. Ghosh, CSMCRI Chemical Sciences Goyal Prize, Kurukshetra University Dr. J.S. Yadav, IICT President of Catalysis Society of India Dr. S. Narayanan, IICT (2005-07) Best Scientist Award by Federation of Dr. R.B.N. Prasad, IICT A.P. Chambers of Commerce & Industry, Hyderabad Dr. S.D. Thirumala Rao Memorial Award CSIR Annual Report 2004-05 by OTAI Indian Paint Association Award Dr. K.V.S.N. Raju, IICT Prof. B.N. Ghosh Oration Award by Dr. P.V. Diwan, IICT Indian Pharmacological Society, New Delhi O.P. Narula Young Scientist Award for Smt. M.S.L. Karuna, IICT excellence in reaserch in the field of Lipid & Allied Products. AVRA Young Scientist Award (2004) Dr. S. Chandrasekhar, IICT
42 Young Scientist Award (2004) D. Dr. K. Mohapatra, N Amines – Foundation UICT DayAlkyl Orissa YouthForum, Rajiv Gandhi (2004), Rajiv Gandhi Mr. Sadbhawana B. Award R. Sark Societies Catalysisof Association International R. Dr. the A. of Fer Council Prize, Scientist Young Dr. A.A. Natu, NCL Sciences Chemical in Medal INSA Youngfor Scientist (2004) P. Dr. P. Wad Award R. V. Chaudhari,Dr. Ranade, (2004) Dr. M. Sastr Foundation Polymer Maiti Sukumar Prof. (Chemistry- 2003) Scientists Young for Prize Goyal Rajiv LABDHI-RDE Award Dr. S. Radhakrishnan, NCL R. Dr. Chaudhar V. K. Dr. N. Ganesh, NCL of Catalysis Society Award of (2005)India S.K. Bhattacharya Eminent Scientist Academy; Science National Indian of Fellow M. Dr. G. Kulka R. Dr. A. Joshi, NCL Engineering of Academy National of Indian Fellow MRSI (2005) Medal R. Ped V. Dr. Medal CRSI Silver (2002) N V. Ranade, V. Dr. Chemistry in Prize Science M. Birla B. VASVIK 2002 Award Dr. T.K. Chakrab Sciences (2004)Engineering Shanti Swarup Bhatnagar prize in Andhra Pradesh Scientist Award 2005 P. Dr. IndiaUsha Association. R ResearchZoologists Applied by Dr. (Mrs) Rao Jagadiswari Award (2004) 43 NCL y, y, NCL nandes, nandes, NCL ireddi, NCL ireddi, ani, ani, IICT gaonkar, NCLgaonkar, ar, ar, NCL rni, Dr. Dr. V.V. rni, orty, orty, IICT i, i, NCL CL CL
S&T Contributions CSIR Annual Report 2004-05 Fellow of Indian Institute of Chemical Dr. S. Devotta, NEERI Engineers Elected fellow of Indian Institute of Dr. P.G. Rao, RRL-Jorhat Chemical Engineering
S&T Contributions S&T CRSI Bronze Medal for the year 2004 in Dr. R. C. Boruah, RRL-Jorhat recognition of the research contribution in chemistry
1.4 EARTH RESOURCES & NATURAL HAZARDS ASSESSMENT
Two CSIR laboratories NGRI and NIO are exclusively devoted to R&D for earth resources. R&D programmes, both through Network and Non-network projects, were taken up for new hydrocarbon resource location, estimation of recharge of ground water systems, mineral explorations and seismic studies.
1.4.1 Progress under Network Projects
I. STUDY OF MESOZOIC SEDIMENTS FOR HYDROCARBON EXPLORATION
The objectives of the project are application of new strategies of integrated geophysical studies of seismic refraction, gravity, magnetotellurics and deep resistivity sounding for the delineation of Mesozoics basins in areas covered by Deccan Traps which are likely to contain oil and gas; Investigation of unexplored areas for hidden Mesozoic sediments for oil and gas; Location of prospective hydrocarbon potential structures in the study area.
CSIR Annual Report 2004-05 PROGRESS:
Gravity observations at 2050 stations completed and data has been processed. Data acquisition for deep resistivity sounding of 31 stations in the eastern part completed of which data processing for 20 stations has been carried out.
II. DEVELOPMENT OF TECHNIQUES AND METHODOLOGIES FOR EXPLORATION, ASSESSMENT AND MANAGEMENT OF GROUND WATER
The project aims at development of techniques and methodologies, and integration of the available advanced geophysical and hydrogeochemical data to thoroughly
44 • • • • PROGRESS: test effectiveness their for a groundwa value added proce the simulate to techniques of development and simulation and contamination geochemical as well as of the fractured and Island aquifer systems to unde investigate various aquifer systems in hard rocks, permeability, infiltration and geophysical changes geophysical and infiltration permeability, geophysical and resp infiltration as permeability, collate the recharge results with hydrogeological r triti injected using (basalt) watershed Ghatiya and Natural recharge studies have been carried out in W dimensional modeling has been designed for the cent the for designed been has modeling dimensional the island. The data on th groundwater in change has the beenassess collecto studied been has Islan Islands Neil on system aquifer on effect tsunami Post well. thro created was ppm 0.7 than less of concentration studie recharge Wailapalli watershed in artificial Nalgonda district. A ground and harvesting Rainwater samples. soil as well Wa of pockets selected some in observed are thorium concentratio High groundwater. contaminate and down concentration high This rocks. and soil in fluoride ur and fluoride ve reveal for studies The completed. been has watershed samples the of Characterization Check dam with capture well 45 dilineation and dilineation characterization rstand rstand the recharge mechanism ter ter management in hard rocks. esponses, investigations such onses, onses, suchinvestigations as ted in the Neil Island. Three- of flow and mass transportmass and flow of ailapalli watershed (granite) ss of artificial recharge and recharge artificial of ss were also carried out. carried also were um technique. In order to order In technique. um of fluoride will percolate will fluoride of e groundwater regime on regime groundwater e water source with fluoride ugh large diameter open diameter large ugh , naa & Nicobar & Andaman d, ry high concentration ofconcentration high ry ilapally in rocks as rocks in ilapally ralized database. ralized wr crid u in out carried were s nu i Wailapalli in anium s f rnu and uranium of ns
S&T Contributions CSIR Annual Report 2004-05 S&T Contributions S&T
Resource well with groundwater III. TECTONIC AND OCEANIC PROCESSES ALONG INDIAN RIDGE SYSTEM AND BACK ARC BASINS
The project proposes to concentrate on Carlsberg ridge (CR)- Central Indian ridge (CIR) and Andaman backarc spreading system to understand the tectonic and oceanic processes that are occurring at these dynamic plate boundaries.
PROGRESS:
Multi-disciplinary investigations have been conducted along the Carlsberg and Central Indian Ridge segments in the Indian Ocean by undertaking two cruises on board ORV Sagar Kanya. During these oceanographic expeditions of SK-201 and SK-207, about 11,176 km swath bathymetry, seabed sampling at 14 locations, and water column data at 55 locations has been acquired. Extraction of Helium from water samples and analysis for 3HefHe ratio were attempted for the first time on especially collected samples. New insights into the tectonic evolution of the Andaman basin have been provided based on the integrated analysis and CSIR Annual Report 2004-05 interpretation of multibeam bathymetry, magnetics, and seismological data. These results brought out, for the first time, information about the topographic fabric and the tectonic configuration of the backarc spreading center. Younger age of opening to the backarc basin than the previously proposed ages was suggested.
1.4.2 Scientific Achievements under non-network programmes
GRAVITY ANOMALIES OF A 2.5D FAULTED BED
An inversion technique coupled with the relevant computer code based on the Marquardt algorithm is developed by NGRI to interpret the gravity anomalies of a
46 densely populated northern continent ofcontinentnorthern populated densely the desert environment to be a good sensor for eart signif observations preliminary These respectively. sub-p and arc Himalayan theto transverse are which epicenters epicenters is found to in be two falling major tren of levels was associated with events global in some ca rat epicent the to proportional distance inversely and distance) magnitude the to proportional directly at distances ranging between 100-800 between ranging distances at order of 5 to 50 cm and was observed prior to earth first time by NGRI. Rise in water level of level water in Rise NGRI. by time first Desert the Thar in observed events were earthquake changes Significant in water levels of shallow and PREDICTION IN CHANGES SUDDEN FOR DESERT EARTHQUAKE WATER-LEVEL constant profile. with density rat information geological existing parabol with on consistent based Interpretations basin. the to due to in of themodel sub-basin Godavari density-depth permissible limits. The of applicability the method est algorithm This sedimentary basin automatically and modifies therea depth. with parabolically varies i basin sedimentary 2.5-D a of bottom the to GRA2P5MO depths code a and algorithm an developed has NGRI BASINSEDIMENTARY TO DEPTHS OF DETERMINATION THE BOTTOM OF A 2.5-D profile. density-depth constantthe geologically yields profile density-depth parabolic th through passes profile the as long as structure, of independent are profile in the density-depth that parabolic shown is it time first the For profile. with comparison in accurate more are profile depth obtained results the that found and profiles, depth with and without regional background using both par other runs at an offset distancebisec from one the origin, o profiles, gravity Two background. gravity capable of estimating shape parameters of a 2.5D-fa contrast the which vari density in bed faulted 2.5D
h st i ai cniin fr atqae precurso earthquake for conditions arid in site the
km. Analysis show the water level changes level water the show Analysis km. 47
India.
the deep well (165-m depth) was of theof was depth) (165-m well deep the f a 2.5D faulted bed are interpreted ds ds of deep borewells deep before borewells and after is with exemplified the derived ulted bed in addition to regional quake quake events having epicenters e origin of the fault plane. The plane. fault the of origin e using performed terpretations hquake hquake management hazard of es with depth. The inversion isinversion The depth. es with ses ses the and signifies sensitivity y the favourable conditions of conditions favourable the y ral distance. The fall in water in fall The distance. ral e hn ihtoe obtainedthose with than her luil mdl ahr than rather model plausible terpret terpret the anomaliesgravity n which the density contrast density the which n ih h prblc density- parabolic the with of India and reported for the for reported and India of fter appropriately fter appropriately within the arallel to the Aravalli Range Aravalli theto arallel c est poie r more are profile density ic ts the strike length and the and length strike the ts abolic abolic and constant density-
h srk lnt o a fault a of length strike the N-S N-S and directions,NE-SW the constant density-depth constant the mts nta dph o a of depths initial imates o (magnitude/epicentral io y tde. h po of plot The studies. ry t dtrie the determine to D
S&T Contributions CSIR Annual Report 2004-05 BURIED IN TIME: CULTURABLE FUNGI IN A DEEP-SEA SEDIMENT CORE FROM THE CHAGOS TRENCH, INDIAN OCEAN
NIO has obtained paleobes, for the first time, from a deep-sea sediment core from a depth of 5904 m from the Chagos trench in the Indian Ocean. Culturable fungi, direct counts of bacteria, age of the sediments based on the radiolarian assemblage, S&T Contributions S&T
total organic carbon, Eh and CaCO 3 were determined in these sediments. Culturable fungi were obtained from subsections up to 370 cm depth. The age of the sediments from which fungi were isolated was estimated to range from greater than 0.18 to 0.43 million years (Ma), being the oldest recorded age for recovery of culturable fungi. Colony forming units of fungi ranged from 69 to 2493 g –1 dry weight sediment with a maximum abundance recorded at 160 cm depth of the core, corresponding to approx. 0.18 Ma. Bacterial numbers in the core showed oscillations corresponding to cycles of approximately 100 ka (kilo years). The fungi comprised non-sporulating forms and a sporulating form identified to be Aspergillus sydowii. Germination of spores of A. sydowii at 100, 300 and 500 bar hydrostatic pressures at 5°C confirmed its barotolerance and its nativity to deep-sea sediments. It is proposed that deep- sea sediments are a source of paleobes, which could be useful in studies on palaeoclimate, long-term microbial survival and biotechnology.
ENVIRONMENTAL INFLUENCES ON THE SPECIES DIVERSITY OF SOFT BOTTOM FAUNA IN EASTUARINE OF GOA
A total of 58 species were recorded belonging to polychaetes, effluent, crustaceans and other minor groups in order of species abundance. Eighteen species are new to the local fauna that were not reported earlier. The maximum mean species diversity index (Shannon-Wiener), total biomass (wet) and total population density recorded were 2.3 (Z1), 6.7 g/m 2 (M1) and 703 no./m 2 (M2) respectively. Significantly higher species diversity was observed at high salinity, fine sand and high sedimentary biochemical parameters of total organic carbon (TOC), total organic nitrogen (TON) and carbon of biopolymeric fraction (C-BPF) sites. The best multiple linear regression model revealed that all the 13 parameters studied were significant CSIR Annual Report 2004-05 influencing parameters on species diversity, biomass and population density with exception of temperature. The combination of significant influencing environmental parameters, percent variation and Mallows’ Cp values varied from sites to biotic parameters. This explained 32-72% of the total variance. The regression model derived from this data helps in detection of these biotic parameters and detection of pollution-induced effects.
48 NIO • • • • • • • NGRI Human Resource Development 1.4.3 • • Colleges of Goa (20 students); (20 Goa of Colleges Biotechn and Microbiology Coursein Training Summer participated. Foreigners and Indian 18 UNESCO training workshop on Dynamic of hard rock aq 125 top ranked SSC (2004) students invited under CP under studentsinvited SSC top (2004) 125 ranked Sri Resources(NARA), Agency & Development Research work on Training/Project Plankton nutrient and anal Forests and (Govt. Indian (21 Forest Serv of India) Training on Management of Coastal Eco-system from M teachers); 2 students+ (22 Jabalpur College, and Techniq Environment Biology, Marine on Training Coastal Research Vessel Nav Malaysian Royal and Navy Indian of officers for Training on Industrial Offshore Survey – A Long Hyd (150 students); Training on Educational Linkage programme from St. Controllin (iv) students); and sediments, coastal in pollution mild steel corrosion, (ii) Marine pollution and eco micro of marine Growth (i) on work Training/Project to the participants;theto Sagar Sukti , carried in order to provide practical training 49 toxicology, toxicology, (iii) Hydrocarbon ice ice Officers); rography effluents course YLS. for ysis AquaticNational Xavier’s College, Mapusa croin f ea (4 metal of corrosion g on organisms– influence y. Field-work, onboard Field-work, y. ues from Govt.ues Science from inistry inistry of Environment ology from different from ology uifers uifers was organised; Lanka;
S&T Contributions CSIR Annual Report 2004-05 1.4.4 Recognition & Awards
CSIR Young Scientist Award (2004) in Earth, Dr. U. C. Kulshreshtha, IICT Atmosphere, Ocean and Planetary Sciences. M.S. Krishnan Gold Medal (2004) by Indian Geophysical Union. S&T Contributions S&T Fellow of National Academy of Dr. V.P. Dimri, NGRI Sciences, Allahabad
National Mineral Award, 2003 of Dr. M. S. Prasad, NIO & Dr. G. Ministry of Coal & Mines, Govt. of India Parthasarthy, NGRI
National Mineral Award, 2003 Dr. R.K. Chadha, NGRI (Geophysics) of Ministry of Coal & Mines, Govt. of India
Krishnan Gold Medal of IGU-2004 Dr. Ajay Manglik, NGRI
IETE Hari Ramji Toshiniwal Gold Shri S. Narayana, NGRI Medal-2004
Vigyan Ratna, 2003-04 Dr. S.W.A. Naqvi, NIO
Fellow of the Indian Science Dr. M. Dileep Kumar, NIO Academy (INSA)
1.5 ECOLOGY & ENVIRONMENT
CSIR has been a major contributor in providing S&T inputs to evolve national policies and to ameliorate environmental problems. CSIR, has developed expertise
CSIR Annual Report 2004-05 in air, water and soil quality management, effluents onshore, offshore & atmospheric environment, near space environment, ionospheric chemistry, stratosphere – mesosphere coupling, ‘toxic & hazardous’ waste management etc. CSIR is achieving these goals both through network and non-network programmes. Significant scientific achievements are outlined below. 1.5.1 Network Projects I. POLLUTION MONITORING, MITIGATION SYSTEMS AND DEVICES WITH APPLICATIONS TO ENVIRONMENTAL ASSIMILATIVE CAPACITY IN SELECT REGIONS The project envisages developing innovative sensors, indicators and instruments
50 revealed accumulation of nitrate and nitrous oxide oxide gas. nitrous nitrous and of formation the for measurements, isotope nitrate to found of are denitrification and nitrification Both accumulation Deccan revealed plain, Indo-Gangetic from collected samples importan climatically of concentrations higher with coast following the southwest monsoon. Occurrence o Time-series measurements showed consistent occurren PROGRESS: seri time long-term through influence anthropogenic o to (from to and decadal) Diurnal improve develo variability to is project this of objective major The IMPACT ONPERTURBATIONS OF ANTHROPOGENIC III. thanrecovery. more95% outwith solution precipitation procedures were to standardized separ plant nickel-plating afor set-up drug-out suitable et tank rinse to plating of ratio volume rinses, of in effluents of stepsminimization Various towards PROGRESS: industries. of categories polluting e also is futuristic, It niche and cost-effective technological remediation. and cleanup s minimization, technological environmental appropriate more into inte resource the dematerializing to proposed is It INDUSTRIAL WASTE MINIMIZATION AND CLEAN UP II. o periods various at load BOD the in variations the optimize been has industry beverage for Biosensor A PROGRESS: mitigation. pollution for for pollution monitoring and study of assimilative INDIA INDIA IN THE CONTEXT OF CHANGEGLOBAL - OCEANOGRAPHIC IN ATMOSPHERIC PROCESSES AND - AROU 51 interventions for at least ten highly capacity of environmental media has been formulated. Chemical formulated. been has be responsible, through stablethrough responsible, be . aebe sadrie. A standardized. been have c. p the capability p the tocapability differentiate f time. f a nickel-plating plant like, no. plant like, nickel-plating a oxide, which is a greenhouse a is which oxide, ate copper from copper drug- r nesadn o natural of understanding ur industries of activities nsive f f plankton blooms associated es measurements. es d taking into considerationinto taking d gss r fud Several found. are gases t ce of hypoxia along the Goa vsgd eeomn of development nvisaged ltos ie a waste at aimed olutions lta ad te areas other and Plateau n rud waters. ground in ND
S&T Contributions CSIR Annual Report 2004-05 1.5.2. Scientific Achievements under non-network programmes
ARSENIC AND IRON REMOVAL FROM GROUND WATER BY CERAMIC MICROFILTRATION MEMBRANE
S&T Contributions S&T CGCRI has developed microfiltration system, which is a novel approach for decontamination of arsenic and iron from groundwater and to cater to the need of safe drinking water for community use. The basic components of this hybrid system are i) absorption of arsenic by the colloidal media particles suspended in water and ii) application of membrane based separation technique for solid liquid separation using ceramic microfiltration membrane module. The salient features of the technology are simultaneous removal of arsenic and iron from highly contaminated groundwater below the limits recommended by WHO; Modular design with flexible production capacity; and Semi-automatic user friendly operating procedure, can be operated by female community members. This technology has been transferred to many Small Scale Industries for mass production. CSIR Annual Report 2004-05 Ceramic Membrane module for removal of Arsenic fron ground water
LOW COST ADSORBENTS FOR REMOVAL OF ARSENIC FROM CONTAMINATED DRINKING WATER
ITRC has developed iron-coated sand for decontamination of water spiked with 50 ppb Arsenic. This material was reused for five consecutive days. The efficiency of Arsenic removal on day one was maximum (90-95%) which declined to 80% on day three and 60 % on day five. The technique can be utilized for water decontamination upto 50 ppb Arsenic level. The materials required are not very costly. Iron coated sand once prepared can be used for three days.
52 water splitting and CO Nox Nox and particulate. In the context of CO flame combustion. This results in lower emissions o te at burning fuel complete and efficient allows it Catalytic methane combustion is a relatively cleane PRODUCTION ENERGY CLEANER FOR COMBUSTION METHANE CATALYTIC conditions.aqueous in stable are synthesized photocatalysts in the presence of UV and visible li activity photocatalytic better show materials These metal transition and semiconductor acid, heteropoly materials consisting of combination of electron don Zeoli properties. photocatalytic improved in result are dominated by variables (F, Ca, Cu, Mg, Zn, Cd, Cd, Zn, Mg, Cu, Ca, (F, variables by dominated are pump). Partial iron) least squares (PLS) modeling reveale phosphate, chloride, groundwater and also between different type of wate demand, oxygen chemical contami and Discriminant analysis composition the identified discriminating groundwater natural for major of responsible identification in helped analysis deposit alluvial ancient and recent the over spread species species to achieve the visible and ultraviolet (UV) fluorine and transition metal compounds and also by htctltc rpris ih epc t dlyd p TiO delayed to respect ze of Tailoring stability. their and recombinations with properties photocatalytic while producing the same amount of energy. In addit In energy. of amount same the producing while NEERI NEERI has developed new photocatalytic materials by APPLICATIONS MATERIALS FOR ENVIRONMENTALPHOTOCATALYTIC region.the in sources anthropogenic ape cletd rm luil ein oeig an covering region alluvial from collected samples data set comprised physico-chemical process parameters and the and variation, spatial its composition, view a with (Unnao) region alluvial the of quality modeling’ statistical ‘Multivariate performed ITRC REGION OF THE GANGETIC PLAINS IN NORTH INDIA ASSESSMENT AND MANAGEMENT OF GROUNDWATER IN ALLUVIAL is being proposed as a cleaner energy route with re with route energy cleaner a as proposed being is 2 , heteropolyacids and suitable transition metals fo metals transition suitable and heteropolyacids , 2 reduction have been used to synthesize the materia 53 2 emissions, catalytic methane combustion photocatalytic activity and better ght. ght. The photocatalytic materials olite materials by incorporating by materials olite mperatures lower than those inthose than lower mperatures r r route to produce energy, since or, charge transfer complex viz, d that the groundwater samples to investigate the groundwater the toinvestigate variables (hardness, alkalinity, f f unburned hydrocarbons, CO, photocatalytic hybrid based te sfcos nlecn i. The it. influencing es/factors as compared to conventionalto compared as SO incorporating other chemical heavy metals in groundwater r r sources (dug well and hand have also been synthesized. been also have o nlz h groundwaterthe analyze to . h picpl component principal The s. latively less CO less latively ra f bu 10 km 2150 about of area n atrpgnc factors anthropogenic and doping TiO r facilitating photocatalytic r facilitating 4 ion, catalytic combusition catalytic ion, ) having both natural and natural both having ) ooeeae electron hotogenerated ewe srae and surface between ain n h region. the in nation 2 with nitrogen, 2 generation ls, ls, which 2 2 and
S&T Contributions CSIR Annual Report 2004-05 can be carried outt in a wider range of air-to-fuel ratio. One of the common otential applications of the catalytic combustion is in the area of natural gas fueled burners for gas turbine power generation.
SIMULTANEOUS DETOXIFICATION AND DECOLOURIZATION OF
S&T Contributions S&T MOLASSES SPENT WASH (MSW)
The wastewaters of molasses-based alcohol distilleries contain brown colored melanoidin pigments that are one of the major pollutants. NIO has successfully decolorized an intensely brown colored molasses spent wash (MSW) by Flavodon flavus , a white-rot basidiomycete fungus isolated from a marine habitat. Polyurethane foam-immobilized-fungus decolorized 10% diluted MSW by 60 and 73% in days 5 and 7, respectively. The immobilized fungus could be effectively used for a minimum of three cycles repeatedly to decolorize MSW. Besides decolourization, the fungus also removed the toxicity of MSW. Toxicity bioassay of the fungus-treated molasses spent wash using an estuarine fish Oreochromis mossambicus showed no liver damage in contrast to untreated effluent, which showed moderate liver damage. Benzo(a)pyrene, a polycyclic aromatic hydrocarbon (PAH) in the MSW is detected and this appears to be one of the causes of toxicity of the MSW. The concentration of PAH in the MSW decreased by 68% by day 5 on treatment with the fungus. This is the first report where decolourization of MSW is accompanied by simultaneous detoxification and decrease in PAH content of the MSW. A comparison of gel filtration chromatography of MSW, before and after treatment with the immobilized F. flavus showed disappearance of the most of the colored fractions in the fungus-treated MSW. A possible mechanism of decolourization of MSW is via the action of glucose oxidase accompanied by production of hydrogen peroxide that may ultimately act as a bleaching agent.
REMOVAL OF CHROMIUM AND CADMIUM FROM INDUSTRIAL EFFLUENTS
Though the presence of the oxides of Mn, Fe, Si and Al are responsible for the CSIR Annual Report 2004-05 adsorption characteristics of industrial wastes but in case of sea nodule residues from two different places, NML has observed that the residue generated at one place is cationic in nature hence could effectively remove cations, another is anionic in nature therefore was found very effective for anions removal. Cr(VI) Sea nodule residue was found to be most effective for the removal of cadmium and Cr(IV) in a concentration range upto 200ppm of Cd and 75ppm of Cr(VI) from waste waters. Red mud was found effective for cadmium and chromate ions upto 25ppm and thus these solid wastes especially sea nodule residue can be used as an effective and economic adsorbent which can also replace carbon- a commonly used adsorbent which is a widely used ones.
54 WEALTH FROM WASTE: BUILDING BUILDING EF BRICKS FROM WASTE: OIL FIELD FROM WEALTH from high sulphur weathered coals and coal fines. coal and coals weathered sulphur high from th manage to levels up scaled and laboratory the in pr The rejects. mine and coals from drainage acidic similari shown have sources non-point and point the the wa effluent to soil, of characteristics The evaluated. variations seasonal with discharged samples characte physico-chemical The systems. water ground sam coal the of heavy metal build-up c possible mines, abandoned of potential generating acid confirmed an pH low with and sul water (TDS), Solids Dissolved Total conductivity, acidic highly of formation the based on the aqueous leaching of the coals from var oxidatio pyrite of mechanism the studied RRL-Jorhat COALFIELDSNORTHEASTERN AND ASSESSMENT MANAGEMENT OF ACID MINE DRAINAGE FRO nickel.of 96% above of recovery overall little very quantity of a promoter. More than 98% n nick high very achieved has conditions moderate the strict environmental protection law.protection environmental strict of nickel and considered as industrial waste, disp It recycling. resource protectionand environmental very is catalyst nickel spent from recovery Nickel CATALYS SPENT A MALAYSIAN FROM NICKEL OF EXTRACTION ecig Sadr sz bik peae uig h s the f using prepared requirement bricks (EPA) size constituen Agency Standard as leaching. Protection fixed are Environmental materials The Control Toxicity ProtocolLeaching (TCLP) tests inorganic pa the provide and burn and hydrocarbons the water, process wat the process, the In bricks. building clay burnt r prepared, Bricks fields. raw by materials the sludge conform to stand Indian brick in condition field the hazardous wastes. The process has been employed de b masonry has common like product RRL-Jorhat value-added preparing hazardous. environmentally is and contains 7-10% hydrocarbon (permissible limit is 3% The The ETP of Lakwa oil generates field about 12m SLUDGE (ETP) PLANT TREATMENT
NML has developed a process, which under which process, a developed has NML 55 3 sludge per day. The sludge often ter samples and sediments from sediments and samples ter osal osal of which is controlled under ious ious collieries. The study shows for safe disposal by land filling) ickel ickel is recovery withachieved phate ions. The study has alsohas study The ions. phate is also one of the rich sources rich the of one also is show that the meet bricks the r n h sug sre s the as serve sludge the in er ocesses have been developed been have ocesses ard for ard specification common e acidic drainage, simulated drainage, acidic e motn fo te iw of view the from important paig bu 3% f the of 30% about eplacing n and consequencesthereof, and n ontamination in ontamination surface in and ties with those of simulated of those with ties el recovery in presence of a of presence in recovery el for for production brick under ery ie sses are systems river nearby ls rm h atv and active the from ples itc o te ie water mine the of ristics is eainhp with relationship its d uilding bricks utilizing bricks uilding eoe a rcs for process a veloped ta fe requirement fuel rtial ug ad iig in firing and ludge s f h bricks. the of ts r rc metal trace or FLUENT T M
S&T Contributions CSIR Annual Report 2004-05 a commercial coal fired kiln show high compressive strength and low water absorption capacity. This development helps the sludge disposal problem.
1.5.3 Human Resource Development S&T Contributions S&T ITRC
ITRC conducted the following workshops in the year: Training Workshop on Scientific Communication; Workshop on Research Methodologies and Statistical Methods in Biomedical Research; Workshop on Current Techniques in Genetic Toxicology; Environmental awareness programme in school children.
NEERI
• Biodiversity training programme sponsored by Ministry of Environment & Forest was conducted for IFS Officers
• Environmental training programme sponsored by Ministry of Environment & Forest was conducted for IFS Officers
• Management; Environmental Impact Assessment: Training programme sponsored by Ministry of Environment & Forest was conducted for IFS Officers
• Water and Wastewater Management training programme sponsored by Ministry of Environment & Forest was conducted for IFS Officers.
• Food Processing Industries training programme sponsored by Ministry of Environment & Forest was conducted for IFS Officers.
1.5.4 Recognition & Awards CSIR Annual Report 2004-05 Fellow of Indian Academy of Neurosciences, Prof. Y.K.Gupta, ITRC 2004 AEB Honours Award-2004 by the Academy of Environmental Biologist
Gujral-Bhargava Oration of Indian Pharmacological Society - 2004 Fellow, Academy of Environmental Dr. R.K. Upreti, ITRC Biology Fellow of the Society of Toxicology Dr. A. Dhawan, ITRC (India), 2004
56 simulated for the full length of the tube. In-house house software developed package Electron MGFLD. be b also has system (PPM) E-Gun Magnet Permanent software Periodical computer available using MPM the for designed electron gun and input and output couplers 99% has been achieved. been has 99% TWT has been processed integrated, and tested. Beam the PPM system to achieve maximum beam transmission with the experimental value and the accuracy was wi em tc o mcoTT o mcoae oe modules power microwave for micro-TWT of stick Beam PROGRESS: systems. power pulse integrated and devices like depressed collectors, components High current their density cathodes tubes, electron power High of fabr for development technology at aims project The I. SPECIAL ELECTRON TUBE TECHNOLOGIES FOR LARGE SCAL LARGE FOR TUBE TECHNOLOGIES ELECTRON SPECIAL I. Network Projects 1.6.1 Optical (ISFETs), transister effect field sensitive of development industry in the the country through development in of spec helped have laboratories CSIR INSTRUMENTATION & ELECTRONICS 1.6 CSIR’s achievements are highlighted in following su following in highlighted are CSIR’s achievements made hybrid microcircuits for the Indian space prog semicon in capabilities trIts magnetrons. & & klystrons microwave in knowledge high-tech of repository iabrPn wr Dr. A. A. Juwarkar, NEERI Dr. P. K. Singh, Pitambar Pant Award Nature Conservator (India). Society of the for Fellow Honorary APPLICATIONS 57 developed software was validated Fibre Amplifier etc. CSIR is the is CSIR etc. Amplifier Fibre and other components, Plasma thin 5%. To verify and optimize ramme ramme and other applications. ductors have provided tailor- provided have ductors ialized products,ialized such as Ion- bsections. for a broadband Micro-TWT ication and characterization and ication transmission of the order of F idw, Multistage windows, RF am transmission has been rfsinl electronics professional , , Beam Stick of the Micro- vln wv tbs and tubes wave aveling e cmltduig in- using completed een n HS. ein of Design HFSS. and (MPM): (MPM): ER has CEERI ITRC E
S&T Contributions CSIR Annual Report 2004-05 II. DEVELOPMENT OF KEY TECHNOLOGIES FOR PHOTONICS AND OPTO ELECTRONICS
It is proposed to develop indigenous technology and packaged products for a number of key components and devices, which play vital role in future communication technology and have enormous market potential such as Optical S&T Contributions S&T amplifiers, In-fibre Bragg grating, Arrayed planar waveguide components and Organic light emitting diodes (OLED).
PROGRESS:
Optical fibre amplifier: For the first time in India an Optical amplifier for light wave telecommunication network has been developed particularly using erbium- doped optical fibre (EDF) and power semiconductor pump laser source. The amplifier gain block with all necessary logic control and computer interface commensurate with CATV and Telecom standards has been designed and developed with an industrial partner, NeST, Cochin. This device is very much helpful in the propagation of “Fibre to Home” technology in the country.
Optical fibre amplifier CSIR Annual Report 2004-05
III. DEVELOPING CAPABILITIES AND FACILITIES FOR MICRO- ELECTROMECHANICAL SYSTEMS (MEMS) AND SENSORS
The development of MEMS based Chemical and Bio sensors, microstructures for Lab-on-a-chip type application in different chemical and biological fields, and micro- cantilever bean array biosensors is envisaged. Ultimately these developments are to be transferred to industry for commercial exploitation.
ISFET based glucose biosensor: This biosensor comprises an ion-sensitive field- effect transistor (ISFET), which is a metal-oxide-semiconductor field-effect transistor
58 ISFET pH sensor: sensor: pH ISFET The test conditions were as follows: drain-source v drain-source follows: as were conditions test The determined by three-point calibration in standard p condit biasing appropriate with electrode reference gate-sour a applying by mode active the in operated re fast and maintenance, for need minimal cleaning, as such sensor pH electrode glass conventional the nitride sensing layer This developed. solid-state d the accompanying changes in gate-source voltages (D voltages gate-source in changes accompanying the output impedance, and inexpensive mass production u production mass inexpensive and impedance, output high preparation, sample minimal cost, low as such off those with systems biological of specificity of we chips biosensor biosens ISFET-based The bonds. mm wire with substrates 3 X mm 3 The gate. dioxi dielectric silicon the over immobilized was enzyme (GOD) width) - 400 provided by an interdigitated source-d semiconductor (NMOS) process. It has a high aspect fabricated device mode enhancement N-channel an is responsive to a solid-stat hydrogen ions, producing The typical pH sensitivity of silicon nitride gate gate nitride silicon of sensitivity pH typical The pH. of decade per mV 50 ³ be to estimated experiment these on Based measured. were potentials MSE) ih h mtl ae elcd y chemical a by replaced gate metal the with (MOSFET) current current I the above value by varying the gate-source voltage voltage gate-source the varying by value above the DS = 10 mA in pH=10 solution. The drain-source curren The The packaged ISFET device with and without its prot The N-channel ion-sensitive field-effect transistor field-effect ion-sensitive N-channel The 59 ISFETs is 53-55 mV/pH. 53-55 is ISFETs evice evice has many advantages over rd ysldsae technology solid-state by ered rain geometry. Glucose oxidase H = 4, 7 and 10 buffer solutions. ions. Its pH Its pH response ions. has been oltage oltage e pH-micro-sensor. The e ISFETThe pH-micro-sensor. ratio (channel length/ channel V sponse. The device has beenhas device The sponse. ce voltage through Ag/AgClthrough voltage ce or combines the advantagesthe combines or irsz, outes easy robustness, microsize, GS nu ipdne n low and impedance input V by the n-well metal oxide metal n-well the by in pH=7 and 4 solutions;4 and pH=7 in sing IC technology.IC sing , h p sniiiy was sensitivity pH the s, ective cover GS ebae (SiO membrane e one o ceramic on mounted re eslcn ird dual- nitride de-silicon V gvn h interfacialthe giving ) DS = 2 V, drain-source V, 2 = t was maintained at with silicon with 2 -Si 3 N 4 )
S&T Contributions CSIR Annual Report 2004-05 IV. ELECTRONICS FOR SOCIETAL PURPOSES
The project aims to develop electro-optic systems for sorting, grading packaging & storage of agricultural products, prosthetic instrumentation and medical instruments calibration and natural hazards mitigation. S&T Contributions S&T PROGRESS:
It is proposed to develop electronics based systems especially for the sectors of Agriculture, Health and Natural Hazards Mitigation.
Electro-optical system for sorting, grading and packaging of apples: The opto- mechanical assembly of the chamber has been developed. Experiments have been conducted on spectral characteristics for different external defects like bruises and cuts in apples.
Intelligent Prosthetic Devices for Rehabilitation of Physically Challenged:
Artificial Knee: Hydraulically operated artificial knee joint with rotary vane system, damping system and hydraulic chamber has been developed.
Functional Electrical Stimulation System: The prototype of programmable functional electrical stimulation system has been developed. Preliminary clinical trials have been conducted on a paraplegic patient at Government Medical College & Hospital (GMCH), Chandigarh.
Seismic Alert System to Avert Colossal Losses during the Occurrence of Major Earthquakes: Algorithm and software for estimation of magnitude of earthquake has been developed. Testing is in progress with real seismic event. Lab testing of engineering model of Weak Motion Recorder has been completed.
Instrumentation for Monitoring, Detection and Early Warning of Landslides: Data CSIR Annual Report 2004-05 Acquisition System has been developed for acquiring/logging data of various geotechnical sensors required for monitoring the landslide. Necessary communication link (Optical fibre link) for transmission of acquired data from data acquisition system to local controlling station has been completed. For data analysis & interpretation (at local control station), necessary software modules for the sensors have been developed.
60 uoai tmeaue opnain a be provide been has accuracy. compensation temperature Automatic d to controls minimum with versatile accurate, use, near the tip where moisture of the oil gr and seeds metallic sensors embedded in a probe, electrically system, microcontroller and display unit. The sensi measuremen inc with increases moisture This conductivity. in variations for system a developed has CSIO PROBEMOISTURE DIGITAL unit. generation a and unit, function exponential unit, sine-cosine 45 instructions and has several dedicated floating- for visually challenged and speech-challenged perso to-speech synthesis. It has the potential for use i set Processor (ASIP) based on Klatt’s parametric fo CEERI has developed a ‘Voice Chip’, is which an App “VOICE CHIP” OF FOR SYNTHESIS TEXT-TO-SPEECH HINDI 4 mohm, watt,T-220. Package: Power: protection. The size of the substrate is 6 x 6 mm 6 x 6 is substrate the of size The protection. technique reflow solder using header on resistor of and conductor for attachment on metal header, scrib dry wer printing, preparation, screen and mask involves resistors power type non-inductive value low of IGBT, SMPS, Small motor drive moh was 25 designed resistors and deve power type non-inductive value Low TYPE POWER VALUE RESISTORSNON-INDUCTIVE LOW Scientific Achievements under non-network prog 1.6.2 Digital Moisture Probe 61 n n embedded systems and appliances point and integer arithmetic units, insulated, insulated, except at contact point ng system consists of two special reasing moisture. It has sensinghas It moisture. reasing 2 ains is registered. It is toains registered. simple is rmant rmant algorithm for text-Hindi wt seiiain:Vle 25 Value: specifications: with ing, ing, lead attachment, mounting admnme ae noise based random-number and high temperature epoxy temperature high and ns. ns. The ‘Voice Chip” supports ing and firing of resistor film resistor of firing and ing lication Specific Specific lication Instruction- trie osue content. moisture etermine loped. 10 prototype samples fbiae. h process The fabricated. e m, suitable for MOSFET, for suitable m, rammes , hc i bsd on based is which t, t esr optimal ensure to d LANGUAGE
S&T Contributions CSIR Annual Report 2004-05 COEFFICIENT OF HAZE AND DUST MASS MONITOR
CSIO has developed Microcontroller based coefficient of haze and dust mass monitor, which determines the instantaneous and average level of black dust mass concentration alongwith Coefficient of Haze (CoH) at ground level. A pump draws air at a predetermined constant flow rate through a sampling head and the dust S&T Contributions S&T particles are allowed to deposit on a filter for a fixed time. A dust spot is, therefore, formed on the filter paper proportional to the dust load in the ambient air. Before the sampling of dust, the microcontroller (8051) reads the intensity of transmitted
light through blank filter paper (I 0) and latches this data in the memory. At the end of sampling time, the spot on the tape is moved in front of photodetector very precisely with the help of a stepper motor. The motion of the stepper motor is controlled by microcontroller.
Microcontroller based COH and Dust Mass Monitor
SMART CARD OPERATED PRE-PAID ENERGY METER
CMERI has developed a working prototype of a single-phase card operated energy meter using the latest technology using a popular microcontroller, smart card, ASIC based energy measurement unit and latching relay for load disconnection. The meter consists of a energy measurement unit , a card programmer / vending machine, a card reader, microcontroller based control logic, alarms and displays CSIR Annual Report 2004-05 and a load controller. The Energy Measurement Unit basically consists of voltage and current sensors, signal conditioning circuits and energy processing unit. The energy processing ASIC directly gives the average real power information in the form of low frequency outputs. The Card Vending Machine is interfaced to a PC via RS232C interface. This is used to program the card using a user-friendly and simple software. Smart card technology has been used for transaction of electricity. Microprocessor smart cards have high memory capacity and a microprocessor, enabling them not only to store information but also to carry out local processing on the data. They have a high guarantee of security with respect to users. An intelligent card reader is used to read the card and is provided with an RS 232C interface. These are engineered to perform at least 50,000 operations. The reader
62 CGCRI • • • • • CEERI Human Resource Development 1.6.3 zero.is net theafter credit 25% net credit thalarm after updates 75% and energy credit is energy consumed. net the computes logic 25% like alarms various indications, controls the the relay on-off for activates load con me display, The LCD read. is data the as which themicrocontroller reads computescard, the soon as card the erases • • • Design; Architectu VLSI Design; on Laboratory Design; Subsystem VLSI on VLSI Laboratory High-level on prepared Design and Related Software”, four learning materia D Manpower “Special project DIT-sponsored the Under Chemical analysis of ceramic and allied materials. allied and ceramic of analysis Chemical par (58 industry ceramic in conservation energy (i) Two programme training-cum-demonstraiton organized the attended participants (50 making glass bead and novelty china bone insulator, tension low and (HT) th in Centre Khurja by organized programmes HRD Six wer participants (28 organized engineering material field the to related programme training term Short institutions. academic various from students (Hons) MCA/ME/M BE/B.Tech. year final to provided Training fr 40 visit studentsofBikaner DST, Technical from Technology”.“IC fro Delhi IIT, from students M.Tech. 14 to Training Colleges. Engineering to provided been have LMs these of each topics Two 63 nection/disconnection. The control It also gives a load-off indication net credit energy, net energy, updates thecredit om 25.5.2004 to 25.5.2004 om26.5.2004. e LCD display. It indicatesIt display. LCD e ticipants attended) and (ii) and attended) ticipants m 24.5.2004 to 3.6.2004 on 3.6.2004 to 24.5.2004 m e trained) e l l (LM) modules have been ware, stoneware crockerystoneware ware, prorgramme) of ceramic, chemical and chemical ceramic, of e i dsge uig a using designed is ter e cei ad load-off and credit net IITs and other reputedother and IITs Verilog-based Digital Verilog-based e field of high tension high of field e evelopment for VLSI for evelopment by by Naroda Centre on e ad Systems; and res .Tech/M.Sc./B.Sc.
S&T Contributions CSIR Annual Report 2004-05 CSIO
• 12 th Management Development Programme on Operation, Maintenance and Repair of Biomedical Equipment
• 5th Management Development Programme on Operation, Maintenance and S&T Contributions S&T repair of analytical equipment.
• Training Programmes on Repair & Maintenance of Bio-Medical Instruments for Hospital Technicians/Doctors
• Courses Conducted by Indo-Swiss Training Centre (ISTC) of CSIO
Diploma in Instrument Technology
Advanced Diploma in Mechatronics & Industrial Automation
Advanced Diploma in Die & Mould Making
1.6.4 Recognition & Awards
Punjab Ratan Award Dr. R.P. Bajpai, CSIO
K. Suryanarain Rau Memorial Award Shri N. S. Mehla, Shri S. C. Jain, for Smart Technology Development Dr. A. K. Aggarwal, and Dr. R P for the Year 2004 Bajpai, CSIO
Fellow of the Indian National Dr. H.S. Maiti, CGCRI Academy of Engineers, New Delhi
President of West Bengal Academy of Dr. H.S. Maiti, CGCRI Science and Technology, Kolkata CSIR Annual Report 2004-05 MRSI Medal, Materials Research Dr. Goutam De, CGCRI Society of India
Hindustan Dorr-Oliver Award – 2004, Dr. Sibdas Bandyopadhyay, Indian Institute of Chemical Engineers CGCRI
Certificate of Merit, Govt. of Tripura Iron Removal Plant of CGCRI
Chartered Scientist – The Institute of Dr. K.N. Maiti, Scientist-in-charge, Materials, Minerals and Mining, UK Naroda, CGCRI
64 acids and Ricinoleic acid estolide (dimer) methyl e methyl (dimer) estolide acid Ricinoleic and acids pentaeryth and Trimethylolpropane oil; mustard from a erucic of Enrichment for developed were processes used scale plant toas pilot level lab biodegrad be (d estolide acid ricinoleic and esters acid stearic emnal sgr uig omril hrotbe en thermostable y selected using achieved was ethanol to conversion commercial using sugars fermentable Conve glucose. on 45% yield ethanol giving IIPE-453 below: t of Some industry. Indian the by required products strengths existing liquid in different tolaboratories by net coal of conversion and gasification coal efficiently to has coals. Itbeen a pionee inferior from pollution India of belt coal the in units coke small of myriad the and strategies washing evolving cok on decide to industry steel the assisted has It and desi from recovery the washeries, beneficiation n developing on working been has It country. the in system. DME and evaluated, fuels screened characterized FT and compared of on h synthesis for catalysts Several PROGRESS: norms. suga ethanol & oils and vegetable from fuels lubricants liquid biodegradable develop to targeted is It NEW DEVELOPING GENERATION FUEL AND LUBRICANTS I. Achievements through Network Projects 1.7.1 In the early years CSIR played a major role in the ENERGY 1.7 Different UDA based alkanol amines, UDA based TMP a Process was for developed ethanol production at 45 65 establishment of the coal washeries working working to develop technologies/ imer) and its acetate prepared on prepared acetate its and imer) able lubricants. Laboratory scale Laboratory lubricants. able r in the developmental efforts efforts in thein developmental r e blends; the power industry in industry power the blends; e rdc ck wt minimum with coke produce ster its & derivative.acetylated gn of mini of gn flotation plants etc.mini ul. SR s yegsn its synergising is CSIR fuels. he achievements are outlined are achievements he igh pressure fixed bed reactor east strains at 10L scale. 10L at strains east cid containing acyl glycerols acyl containing cid and medium sized beehive sized medium and fines coal to approaches ew rsion of rice, wheat flour to flour wheat rice, of rsion rdcin rm biomass, from production s n t st p emissions up set to and rs ytei wr prepared, were synthesis o C a by strainthermophilic ritol esters of undecenoic of esters ritol nd PE esters, tri hydroxy ye n is further its and zyme
S&T Contributions CSIR Annual Report 2004-05 II. COAL CHARACTERIZATION & RESOURCE QUALITY ASSESSMENT FOR SPECIFIC END-USERS
The project aims for detailed studies with respect to petrographic characterization and coking behavior of coal, gainful utilization/value addition of North East (NE) coal directly or after suitably blending, developing appropriate technology for S&T Contributions S&T carbonization/combustion and/or after sulphur cleaning by suitable process and also the recovery of precious and rare metals from pyritic wastes, if possible, Mathematical modeling for prediction of composition of gas as a function of operating parameters and properties of coal for gasification reactions.
PROGRESS:
Testing of coals at different carbonization conditions were conducted in a laboratory scale furnace. Desulphurization ratio in the range 17-19% has observed in the lower temperature range below 1000 oC. A nano particle-based material has been developed and characterized for carbon dioxide absorption. Kinetic studies on reactivity measurements as well as active and reactive surface area has been determined on seven low rank coals. Methodology for determining true density of coal using nitrogen has been developed. This will change the current methodology of determination of true density by helium.
III. QUALITY ENHANCEMENT OF COAL FOR ITS EFFICIENT UTILISATION
The project envisages to identify the optimum beneficiation strategy of non coking coals to meet the needs of different end users; To assess the effect of blending of coals, (indigenous & imported) on efficiency of power generation and evolving strategies of blending of dissimilar coals. Use of Computational Fluid Dynamics (CFD) as a modeling tool of the different sub-processes like Spiral, Cyclone and flotation for improving the design and performance of existing systems. Application of different physical processes for treating non coking coal fines. CSIR Annual Report 2004-05
PROGRESS:
A no. of samples from different coalfields were collected for detailed characterization studies. Detailed washability investigations suggest similar washing characteristics of both Hingula and Belpahar coals of Mahanadi coalfields. Yields at 34% ash level are predicted taking help of Computer simulation studies. Blending of Belpahar (MCL) & Sonepur (ECL) coal was studied. Combustion characteristics of the above blended coal samples are studied in the Drop Tube Furnace. From the combustion characteristics of blended coal it is found that high ash Belpahar coal can be blended with the low ash Sonepur coal. Two samples
66 respectively. The study reveals that nitro groups groups nitro that reveals study The respectively. to 25%, and from 56.2% to in 29.3% aqueous acetone ovninl n Jmsn el Wees oun flota column Whereas level.ash 18% at yield 76% with promising cell. Jameson and conventional co Knelson on investigation coal indicates fines Spiral, Patherdih 50- Jameson, column, like techniques proc physico-chemical conventional using fines coal is washery completed. Focus of the study was to im material (2.5%) and material good percentage (2.5%) of S suitable for making prop. It contains fl maximum CaOTalcher ( co strength. tensile as weight, well in as compressive light is prop this as industry mining as binding material and reinforcing material respec prop. Other constituents of this prop are a resin a CMRI has developed a flyash based mine support as a MINE BASED SUPPORTFLYASH Scientific Achievements under Non non-network 1.7.2 even to 6 mm. The characterization observed, was studiesliberation onsignificant the No potential. sam the both on out carried was studies washability 13 mm, 25 mm. 75 sizes at studies crushing Detailed Coal Coking Bharat of OCP Muraidih and OCP Satabadi ie. o hscl n mcaia cagswr obse were changes mechanical and physical No mines. conditions were also investigated by the installing good compressive and tensile strengths. The behavio bulk makes low Goprop, it light density in weight. mater combustible the of content less While (0.74). elimination elimination of NO solvents. Heat treatment of the oxy-nitrated coal coal oxy-nitrated the of treatment Heat solvents. solubilizati the enhanced substantially group nitro and aqueous tetrahydrofuran. The experimental resul det were introduced, was group nitro which in coals The acid. nitric dilute using nitration oxidative bit rank solvents. organic nitro The group was i introduced low two of solubilization studied has CFRI DIRECT SOURCING OF COAL FOR CHEMICALSVALUE ADDED tonnes.of 8 theto load withstand found of a two period environment during months of experi 2 and lowering of solubility in potent mixed solvent 67 i 0 2 (56.63%). Its bulk (56.63%). density is the lowest coal fines collected from Patherdih nd a fibre, nd which a fibre, have been used 60% yield at 17% with60% ash yield level, solubility of raw coals and the and coals raw of solubility m m at New Pit and coalHorladih tively. tively. It is highly useful for the yash has emerged as the most the as emerged has yash od od percentage ensures of silica n the of matrix organic coal by ial reduces the fire risk of theof risk fire the reduces ial on of coal in aqueous organicaqueous in coal of on when the coals were crushed were coals the when prove prove theof yield cleans from rsn i oyntae coals oxy-nitrated in present 1.82%), very little combustible and and aqueous tetrahydrofuran ur ur of the props actual in field suitable substitute for timber mm and 6 mm followed by followed mm 6 and mm ermined in aqueous acetoneaqueous in ermined tefcie n bas good bears and st-effective ts reveal that introduction of mentations. mentations. propsThe were ples to assess the liberation the assess to ples t 150±10 at mnu cas n aqueous in coals uminous se ad te advanced other and esses cnrtr Preliminary ncentrator. vd n the in rved Limited were collected. were Limited programmes in a fud more found was tion 0 i ar caused air in C s from 49.5% in situ situ in mine
S&T Contributions CSIR Annual Report 2004-05 played an important role in solubilizing it in aqueous organic solvents. The decrease in nitro group was detected by the FTIR difference spectra and was confirmed by material balance data. A hypothetical route of nitro group elimination and a possible mechanism for reduction of solubility of oxy-nitrated coal consequent upon its thermal treatment in presence of air have been put forward for the first time which is substantiated by FTIR spectra. S&T Contributions S&T
1.7.3 Human Resource Development
CFRI
• Training course on coal carbonisation/ coke ovens for staff of coke oven plants, Durgapur Projects Ltd.;
• CPYLS Programme: Twenty three, class XI students from various schools of CBSE and ICSE Boards within Bihar and Jharkhand State, participated in the programme;
• Vocational training/summer training programme for the students of various colleges, Universities/ technical institutions.
IIP
• XI Training programme on ‘Advances in Petroleum Refining Technology and related aspects’ for senior executives of different refineries was organized during April 28-30, 2004.
• Four-week training programme on ‘Petroleum refining technology was organized for Chemical Engineers during September, 2004.
• Various training programmes on ’Petroleum refining technology’ was organized for fresh Chemical Engineers during October & November, 2004. CSIR Annual Report 2004-05 • Workshop-cum-training programmes on ‘Vehicular pollution’ were organized during October & December 2004.
68 100% TFA containing ethane dithiol. The purity of t of purity The dithiol. ethane containing TFA 100% cleave was peptide The resin. MBTH amide rink using AVP a (Ala-Val-Pro), tripeptide, was synthesized by PROGRESS: nu called approach this for way pave ultimately may on the health benefits from a variety of plant reso curative management and of several systematic and c and nutrigenomics through study of molecular basis The project envisages repositioning India’s leaders 1.7.4 Recognition Recognition & Awards 1.7.4 I. POSITIONING POSITIONING INDIAN NUTRACEUTICALS AND NUTRIGENOMI I. Progress under Network projects 1.8.1 bein also are programmes network Three etc. milling besides appropriate and improved designs for a rang foods, spice products, & fruit preservati vegetable ‘convenien preservation, food and foods, nutritious conservation and processing, and has developed vari proces and techniques easy-to-operate and effective co is CSIR processing, food and food of area the In PROCESSING FOOD & FOOD 1.8 fedo hmclEvneigIIP Dr. Jasvinder Si II Envineering Chemical of field in the TechnocratsAward Excellency Research. Petroleum field in Award Excellencies CFRI Dr. K. Technocrats Intellectuals Conference Sen, of CFRIIndia All ‘Uttraanchal Ratan’ Mrs. N. Award in ‘Indian Petroleum Cate India of Institute Metallurgical Geological Mining The by 2003-04 year thefor Award” Petrology Coal GhoseMemorial Subrata India of Association CCAI-2004 by Award Coal Consumers IN IN A PLATFORM GLOBAL 69 urces and their ingredients, which on, on, & packaging transportation, hip hip in the area of nutraceuticals of bioactives for the preventive, ntributing several novel cost-novel several ntributing solid phase FMOC-chemistry e of machinery for processing, ous technologies for low cost- he peptide was evaluated by evaluated was peptide he hronic ailments. ailments. hronic focusThe is e od’ non-conventional foods’, ce e fr od ris storage, grains food for ses trigenomics. g implemented in this area. this in implemented g gory’ Dr. Dr. M.O. Garg, gory’ d from the matrix using matrix the from d P Choudhury, ngh, CS
S&T Contributions CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 S&T Contributions omto o vnli faor rm aiu intermed various from compounds. flavour vanillin of formation p could which 6.0), (pH (POD) peroxidase of weight) Mature fruits were found to possess a very high lev VANILLA PROGRESS: com develop to targets project biomolecules. The biomolecules. of countryeven the and limited is availability their biomolecu such for demand huge of Inspite purposes. als nutriti and health, for times ancient biodiversity from biomolecules rich with country the is India OR NATURE-IDENTICAL NATURE, SIMILAR BIOMOLECULES II. value is several fold higher thanIC the The pentapeptide ACE. lung and kidney amino acid composition. The ACE activity inhibitory amino-termi by verified was peptide the of sequence RP-HPLC using the TFA/CH3CN solvent system and foun major component identified.component major accounted which Vanillin, components. for analysed, of dichloromethane and n-pentane. The solvent was t in desiccators for 6 days) was powdered, extracted drying of cured beans was assessed using gas chroma extraction and apparatus Nickerson Likens employing e liquid liquid mixture, solvent with beans vanilla Vanilla flavour resulting from various techniques n techniques various from resulting flavour Vanilla 50 au o AEihbto ws 65g hs IC This 36.5µg. was inhibition ACE for value Cured vanilla beans 70 VLIVP and therefore less effective. depends on import of a number a of import on depends using solvent mixture consisting el el 2000 (nearly units/g of fresh on and horde of other useful other of horde and on hen distilled using water bath, tography. Cured beans (dried tato, lvr preparation flavor xtraction, was evaluated using porcine for 64% of volatiles was the was volatiles of 64% for lay an important role in the in role important an lay wt taiin n s of use in tradition with o a sqec nlss and analysis sequence nal with solvent mixture after mixture solvent with amely, direct extraction of extraction direct amely, les throughout the world, the throughout les ay phenylpropanoid iary ecal exploitable mercially d d to be >99% pure. The 50 gene of GM-soya were developed. The CP4 EPSPS gene copi specific detect/construct to methods based DNA PROGRESS: pres or absence declared their on based items these produ food and food for center referral a establish their evaluate and products a GM to of levels ingredients threshold food and foods in (GMOs) Organisms quantit accurately to methods robust well-developed It is imperative for the Government to have testing III. ESTABLISHMENT OF GENETICALLY MODIFIED FOOD REFE FOOD MODIFIED GENETICALLY OF ESTABLISHMENT III. of snake venom PLA venom snake of which binds to specific sites, localized on the mid the on localized sites, specific to binds which systems for preservation and as supplements in heal in supplements as and preservation for systems ap have extracts These concentration. ppm 40 at BHA tois which comparable respectively, the ( activity activity of the conserve is about 55-80% and 90-93% for scavenging radical activity using model DPPH sy The conserve 8-10%) (yield: obtained after the proc VALUE ADDITION TO COARSE TEA LEAVES have been identified. been have acid, benzoic 4-hydroxy acid, caffeic acid, gallic methanol solvent, concentrated and by identified HP the seed coat fraction of GPU 28 variety of finger non-GM soya. b soya GMin detectable was fragment 169 and 447-bp analys sequence DNA by confirmed was sequence whose This region. border cross the of segment smaller a border region fo between and CP4EPSPS. Primer sequenced pair was GMO amplicon 07/ bp 447 The the amplified. and EPSPS between region construct the amplify U tolerance. herbicide develop to inserted been has inhibitory activity is found to be 50 and50 be to found is activity inhibitory Investigations on the effect of the millet polyphen the millet of on effect Investigations the The Cry1Ab gene, inserted in GM-Maize (MON 810) cod 810) (MON GM-Maize in inserted gene, Cry1Ab The Generally, cereals are poor source of plant polyphe plant of source poor are cereals Generally, FACILITY 2 n te nlmaoy PLA inflammatory the and 71
63% respectively. 63% millet millet were extracted using acidic syringic acid and coumaric acidcoumaric and acid syringic 90-94%) of 90-94%) synthetic antioxidant or centers referral in place with essing essing of Green tea is evaluated cts, which will boost export of export boost will which cts, at 5 and 10 ppm concentration ence of the GM component.GMthe of ence sing various primer pairs that pairs primer various sing gut epithelium of susceptibleof epithelium gut LC. Ferulic acid, vanillic acid, amplified a 196 bp fragment bp 196 a amplified 2 stem. The scavengingradical th foods.th ols on the inhibitory activity theon inhibitory ols ae en are ot Its out. carried been have aey Te rjc am to aims project The safety. ut was not amplified in the in notamplified utwas es of the herbicide tolerant herbicide the of es of GM08 was used to amplify t Gntcly Modified Genetically ate lcto i vros food various in plication nols. The phenolics from phenolics The nols. aV5 rgltr was regulator CaMV35S
und to contain the cross the contain to und Agrobacterium tumefaciens sr cmlac with compliance ssure s Sy E4P gene EP4SPS Soya is. es for d-endotoxin, for es RRAL
S&T Contributions CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 S&T Contributions CaMV35S and exon 1 of the heat shock protein yields protein shockheat the of 1 exon CaMV35Sand CaMV35S and intron 1 of the heat shock protein. The detection of an amplicon of 401 bp confirms the pre using were amplified the primer pairs Mg1/Mg2 and M the of heat respectively were protein shock Exon 1 CaMV35S the between sequences border cross specific endonu restriction with digestion by and sequencing sequence gene The samples. maize 810 MON the all in detected by using a pair of primers VW01/VW03. A 17 an a 35S CaMV element low regulatory the between as sequence levels at detected be could amplicon 194bp Cry1Ab the of fragment bp 194 a amplify to used was pr The therefrom. derived those and food unambiguous engineered the for used be can thus and unique are 0.1. as low as levels at detected be could amplicon 204 bp fragment. A 204 bp fragment was detected syntheticin the of detection specific for used were R used to develop DNA based methodology. The primer p potenthighly and mid with interferes and species insect lepidopteron cd n mxd ri pl floe b frhr conce further by followed pulp have flavourants also spice been inc Alternatively, fruit mixed and acid product has also jellie been by developed thetreating sap jam, spread, of manufacture the for material nutr highly is product The C. vitamin and phosphate tofound was odour, in be rich nutrients and minera alcohol to an extent of as6%, soon as it is tapped the sap. Coconut sap was found to undergo lactic an collected deodourised sap, and concentrated. A palatable coconut nutritiou The sap. coconut fresh from o preparation the for process a developed has CFTRI SAP COCONUT NUTRITIOUS FROM PRODUCTS below: presented are and application oriented R&D in non-network laboratorie mode CSIR al activities, network to addition In Scientific Achievements under pro non-network 1.8.2
specific insecticide. Hence detection detection of this gene Hence insecticide. specific 72 . . sap, The in spite of its obnoxious sence of the cross border between d acidic fermentation to produce orporated instead of fruit pulp.of fruit orporated instead also detected. These sequences also detected. cross border sequence between a amplifies that gene Cry1Ab s have been involved in basic in involved been have s GM-maize GM-maize samples. The 204bp concentrate with pectin, citric Construct specific sequences specific Construct ls like sugars, citric acid, iron, acid, citric sugars, ls like n cnis A spread-like A candies. and s gut function, thus acting as a as acting thus function, gut s beverage was obtained from cleases. Two other construct other Two cleases. itious and useful as the base the as useful and itious so. Some of the achievements a 149 bp amplicon. bp 149 a imer pair MonF and MonR and MonF pair imer –Hsp construct region. The region. construct –Hsp regulator and Intron 1 1 Intronand and regulator 0bp 0bp amplicon was detected y apn, a clarified, was tapping, by s were confirmed by DNA by confirmed were s 01 . h cos border cross The %. 0.1 s airs airs Cry1Ab F and Cry1Ab ccnt a concentrate sap coconut f g3/Mg4 respectively. g3/Mg4 Therespectively. d the maize genome wasgenome maize the d eeto o genetically of detection grammes tain o 70°Brix. to ntration by PCR by can be and normal or BIS (27 BIS or normal and correct this deformity and increased fragility of e of fragility increased and deformity this correct rat caps hypercholesterolemic curcumin, tocontrols. Dietary normal compared of RBCs affected. also was a result of alteration in membrane structural lipid by a producing in significant decrease (10-14%) mem h in membranes erythrocyte of profile lipid altered thes addition, In effect. hypolipidemic significant powder garlic – spice the or (0.015%) capsaicin or sp of Inclusion ratio. to cholesterol phospholipid resulting control) basal of 120% (about cholesterol membrane diet-erythrocyte on cholesterol enriched a CFTRI has found that in rats rendered hypercholeste SPICES HYPOLIPIDEMIC DIETARYBY ERYTHROCYTES OF INTEGRITY OF PROTECTION weeks.of 3 storage has Itmaximum chromo paper/3-ply paperboard/kraft liner with alum o hp o tpoa bnn ad akri. Moisture jackfruit. and for studies relationships banana tapioca, of chips to CFTRI has carried out packaging and storage studies COST EFFECTIVE PACKAGING SYSTEM FOR A FEW TRADITION 0.9863). Neera, – SAP COCONUT FOR NOSE ELECTRONIC of the coconut palm. palm. coconut the of ult ad esr prmtr. trg suy a c was study containers with inert gas (nitrogen) flushing under Storage parameters. sensory and quality from 64% ranging to product The 90%. evaluated was stud were time with content moisture the in changes shown very good correlation thosewith correlation shown of good very the c gas the from results The sample. the in present alcohol th determine to used is network Neural system. nose ferme their of course the during analyzed been have oxide semiconductor oxide sampling a headspace, the creating for zone heating bein samples the print finger to sensors MOS the of capable of assessing the quality of process, alcohol is produced in it. CFTRI has devel the sugar containing juice or sap, is obtained by
Neera sensors and a data acquisition system. The The system. acquisition data a and sensors 0 C, 65% RH) conditions. The container comprised an o an comprised container The conditions. RH) 65% C, laddu ferments very quickly and even during the collecti the during even and quickly very ferments was studied the towas moisture content.studied critical fix Neera . . The system utilizes the unspecific response 73 NEERA s, s, the structural integrity of RBCs ice principles - curcumin (0.2%)curcumin - ice principles oped a simple analytical system, the accelerated (38 rythrocytes. A further insight further A rythrocytes. thecountered spices dietary e (2.0%) in the diet, produced a produced diet, the in (2.0%) on hromatographic analysis (R analysis hromatographic ypercholesterolemic situation ypercholesterolemic n sgiiat leain in alteration significant a in rolemic- rolemic- by maintaining them chamber, an array of 5 metal 5 of array an chamber, electronic nose system havesystem nose electronic brane brane cholesterol content. As tapping the unopened spadix g analyzed. It has a sample-a has It analyzed. g s were relatively enriched inenriched relatively s were e quality and the amount ofamount the and quality e aicin and garlic appeared to appeared garlic and aicin inum foil and PVDC coating. ntation using the electronicthe using ntation initially for microbiologicalfor initially ied at different humidities different at ied potarekhu, laddu otn - ae activity water - content wr rltvl fragile relatively were s rid u i composite in out arried AL FOODS Neera o , , in addition C, C, 90% RH) samples uter The on 2 2 =
S&T Contributions CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 S&T Contributions Andrographis serpyllifoliaAndrographis no h fcos ht ih hv rdcd h fluidi the r bilayer, membrane the of reduced composition phospholipid have might that hypercholesterolemic rats revealed changes in fatty factors the into induced cellular damage (figure given below). Thus Thus anticancer potential a is compounds antimetastatic below). given (figure damage cellular induced Besides this polysaccharide, SR-phenolics are cytop can in only expressed is which Galectin-3, to binds will this and Arabinogalactan an is polysaccharide analysi composition sugar Comparative mg). (2.5 CPP equivalent of as opposed carbohydrate to those of B inhibitor effective at agglutination inhibited SRPP Decalepis hamiltoniiDecalepis fro (PPS) polysaccharides Pectic prepared has CFTRI CUMIN AND BELESOPPU BLACK ROOT, SWALLOW FROM POLYSACCHARIDES ANTICANCER ISOLATION AND CHARACTERIZATION OF ANTIOXIDANT AND situation. unaffec be to appeared efflux cation active the and this was significantly hyp countered of by dietary erythrocytes capsaic the in increased was population this alteration. Scanning electron microscopic exam in hypercholesterolemic to rats. Dietary capsaicin and erythrocytes of al revealed also parameters anisotropy fluorescence sensitivity the in reduction and normal cells (RBC) as encountered during metastasis during encountered as (RBC) cells normal cance effect mediated Galectin-3 mimics the it since property, understand to enabled assay The (RBC). a induced cells of against HeLa property Galectin-3 PPS even trials. polysaccharide have clinical in be compared with that of citrus pectin (CPP) - reporte
Normal Cytoprotective effect of SR-Aox against oxidative s - Swallow Root (SRPP), (SRPP), Root Swallow - - Bele soppu (APP), (APP), soppu Bele - Oxidative Stressed P 74 iel sativa Nigella Zingiber officinaleZingiber tress induced cellular damage in. in. The membrane-protein profile d d to be an effective antimetastatic en examined for for en inhibitoryexamined their rotective against oxidative stress curcumin significantly reversed ination revealed that echinocyte y concentration ICe - .185 mg .185 - ICe concentration y acid profile of the membranes, cer cell and not in normal cell. normal in not and cell cer gglutination of red blood cells blood of red gglutination CPP (13mg), CPP APP (13mg), and(4.2mg) be cancer- cell specific since it since specific cell cancer- be source. r cell (HeLa) interaction with interaction (HeLa) cell r tered fluidity of erythrocytes of fluidity tered e i hypercholesterolemic in ted
in vivo. in rhlseoei rt, and rats, ercholesterolemic educed Ca educed o-. S seta and spectra ESR Con-A. f oeta antimetastatic potential of deay ore sc as such sources dietary m s indicated that the active the that indicated s R ih nixdn and antioxidant with SR lc cmn (BCPP), cumin Black - y f rtrcts in erythrocytes of ty Results indicate that indicate Results rotected -Ginger (GPP) and (GPP) -Ginger 2+ , Mg , 2+ -ATPase, for the preparation of blackgram blackgram of preparation the for con formulation, mix instant an developed has CFTRI PRODUCTS MARKET SELECTED SPECIFIC FOOD ADDITIVES FOR SENSORY QUALI ENHANCING FLAKING FOXTAIL MILLET ( MILLET FOXTAIL FLAKING snacks containing sorghum for and mix blackgr fried processed Semolina were found to be effective addit such as snacks fried the for developed was additives selected containing ncs ol b dcesd y h adto o enzyme of addition of the by decreased starches modified Enzymatically were found to consi be could snacks CFTRI has developed PCR-BASED DETECTION OF FOODS ‘GENETICALLY-MODIFIED’ variety the enhance products. products These flakes. corn to and such other products. These flakes can be used a legumes and other ingredients traditiona prepare to otherand legumes ingredients pulveri and broken The snacks. ready-to-eat crispy, may flakes grade thicker The snacks. consumption as con spicy with seasoned and water with sprinkled be and other sorghum wheat, to rice, products similar CFTRI has developed the foxtail flakes, millet whic were tested for GM-genes. thefor tested were respectively. To validate the detection method, sam for lectin and starch synthase was used as housekee gen EPSPS modified and terminator NOS virus, mosaic foods, by amplification of the ‘incorporated genes’ Samosa Samosa ihu afcig h snoy ult. n ntn m instant An quality. sensory the affecting without Samosa / Kachori / Karjikai / Kachori / Samosa
a PCR-based method for the detection of genetically STEARIA ITALICA STEARIA Foxtail Foxtail Millet Flakes vad a . Oil content of dough based deep fat fried fat deep based dough of content Oil . 75 . Expanded rice flour and thermally and flour rice Expanded . viz. 35S promoter of ‘cauliflower fter toasting or blistering, similar ives in the formulation of instant ples of processed food products h h are ready-to-use convenience ping ping genes for soya and maize cereal flakes. The flakes could The flakes flakes. cereal l foods like l like foods zed flakes can be mixed with mixed be can flakes zed ) preparation of dough based dough of preparation derably lower derably the fat content am. be deep fat fried to prepareto fried fat deep be taining selected additives, selected taining diments or sweetened for sweetened or diments vial i convenience in available e. Amplification of genesof Amplification e. rae starches. treated Bisi-Bele bhathBisi-Bele x formulation ix modified T Y OF , , Idli
S&T Contributions CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 S&T Contributions conformational changes. From the degree of acetylat index (by X-ray studies) of 60-62% and and 60-62% of studies) X-ray (by index range the in be to found is LMWC of GPC) (by weight depolymerize chitosan to LMWC, CO and monomers, have in pepsin and pronase papain, pectinase, n as such by obtained been crustace from have derived chitosan, of depolymerization They fields. biomedical and ap innumerable find (CO), chitooligosaccharides and The degradation products of chitosan, viz. low mole ACTIVITYSTUDIES – CHITOOLIGOSACCHARIDES STRUCTURAL AND BIOLOGICAL results. good yielded has pes organophosphate of analysis for tested been has t porting and acquisition data for means convenient inter serial the With acquisition. data for channel pump peristaltic two and 24V) (DC valves solenoid 8 ELISA flow different for is steps. customizable It systemThe to is accommodateflexible sequ multiple the of reuse for option the provides also it used, sequence the With analysis. for used conjugates and of flow the control to microcontroller 8952 employs of objective the systemis to developed analyzer pr detectio precise ensures immunoassays of Automation AUTO OF ANALYZER FOR IMMUNOASSAY PESTICIDES leaves and then subjected to further processing. further to subjected then and leaves steaming by either produced is tea green Presently manufa the during leaves tea in inactivation enzyme emp in lies process the of novelty The utilization. Dried leaves were cooled and subjected to leaf dist t reported are which Catechins), (i.e., polyphenols enzymes the inactivate to Dryer Infrared continuous wer leaves withered The moisture. the down bring to Fresh green tea leaves were procured from the estat TEAGREEN pathogens agai activity antimicrobial excellent shown have CO 8, with the preponderance of tetramer and hexamer ( groups intact. The CO mixture has a exhibited degre glycosid only cleave enzymes these that clear is it 76 13 -M dt hv son subtle shown have data C-NMR ortion, and then stored for further applications. It can up It control toapplications. immobilized antibody column. antibody immobilized ovide a user-friendly system. Itovide a user-friendly o show several health benefits. health several show o face port, the system providessystem the port, face ion values (by IR and loying the infrared energy for energy infrared the loying es of hills and Nilgiri withered cular cular weight chitosan (LMWC) ic bonds leaving the N-acetylthe leaving bonds ic HPLC HPLC data). Both LMWC and e of polymerization (DP) of 2- reagents, samples, substrate samples, reagents, ences up to a maximum of 99 or pan firing of the fresh tea fresh the of firing pan or nst several of the food borne food the of several nst an wastes. Several enzymes Several wastes. an ticide methyl parathion and parathion methyl ticide o the computer. The system The computer. the o and flow control of buffersof control flow and cture of superior green tea. green superior of cture plications in biotechnology in plications e subjected to drying using drying to subjected e been utilized to selectivelyto utilized been ad o ean h simple the retain to and , s. It has one 12 bit analog bit 12 one has It s. n with high accuracy. The accuracy. high with n of 4-10 kDa, crystallinity kDa, 4-10 of varying yields. Molecular nseii enzymatic on-specific 13 C-NMR) M.Sc. M.Sc. Food Technology (2 years Duration) positions. course as Management Trainees and thereafter, place Indus Food in absorbed immediately are Participants of Participants of invested invested Rs. 6 crores and has potential to currentl fo plant commercial material) (raw TPD 1 for report has provided technology know-how package pharmaceuticals and IICT and h cosmetics processing, food for Chillies Turmeric, (from colours natural their producing commissioned have Hyderabad Biotech, KCP M/s PRODUCTION OF NATURAL COLOURS • CFTRI: Human Resource Development 1.8.3 Number of the Participantsthe of Number ACADEMICS: n piae raiain, cdma NO, self-Hel NGOs, academia, bene been have institutions other and organizations organizations, private and o 535 comprising participants of entrepreneurs, indus areas varied in i food present the to relevant is which technology, h informatics and programmes knowledgebase the the of effe the and group uniqueness heterogeneous a of participation The programmes. made In all, 36 short-term training programmes were cond : rs mrtros rdae fo eey tt o th of State every from graduates meritorious Fresh : 21; Level of Participantsof Level 21; Infra-red drying of green 77 y y employ 65 persons in the plant. r the client. The companyhas The client. the r d d at various Managerial level and Annota seeds) required seeds) Annota and : at S.P. Biotech Park. CFTRI Park. Biotech S.P. at Post Graduate Level; Type Level; Graduate Post ndustry scenario. A total oftotal A scenario. ndustry as provided detailed design ucted including 10 custom- re n opeino theof completion on tries try personnel, try personnel, government fited. ctive means of providing of means ctive omril ln for plant commercial fo sine and science food f gop, women groups, p s en the been as Country. e
S&T Contributions CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 S&T Contributions Number Number of the 55 Participants: have candidates enro Ph. D. Programme (4-5 years Duration) c the meetto products wheat milled quality high of flourmills and the mills are greatly benefited by t to the progress of S&T in the toS&T country.in of progress the parents were familiarized with prog the thecontribution During ofprogramme. the attended students 37 CSIR Programme for Youth on Leadership in Science ( s training this in universities focus are adequately equipped special to take up given a c are foods to frontier and Emerging areas of Science & Technology term project of 4-6 weeks to one year duration in a stud the colleges, engineering and universities the universities. and colleges engineering various from of Level Postgraduate students; students; Type 120 of Participants: Gradua Participants: the of Number Mi Flour in experience with Graduates Participants: Participan of Level 20; Participants: the of Number Certificate Course in Milling Technology (12 months Training Training of students from other universities and co succe a make to knowledge practical and theoretical g participants The postgraduates. qualified NET UGC Science basic and allied subjects in the year 2004- The students who pass out the course are immediatel are course the out pass who students The Students interacting with a CFTRI Scientist 78 lleges (4 weeks to one year duration) Duration) he he training in terms of production n outside institute / organization. 2005. 2005. Level of Participants: CSIR- CSIR, CFTRI and Indian Scientists hallenging R&D career in future. CPYLS) ents have to undertake a short a undertake to have ents tes and Post Graduate students ts: Certificate Course; Type of Type Course; Certificate ts: ustomers’ requirements.ustomers’ In the curriculum of most ofmost of curriculum the In lling Industry. lling lled for Degree Foodin Ph.D. lled ssful career in R & D. & R in career ssful ta te onses from youngsters the that o with with applicationlong-range et equipped with sufficient with equipped et atcpns Gauts / Graduates Participants: ramme, the students andstudents the ramme, y absorbed in the rollerthe in absorbed y 1.8.4 Awards Awards & Recognition 1.8.4 plmrhs i eo 7 E3G ad CT polymorp C/T a genotyped, a were and Kb, 8.74 of (E237G) length 7 a encompassing exon in polymorphism A p Four investigated. been has population Indian the genetic The association of the beta subunit of lgE PROGRESS: aspects. pharmacological and biochemic covering disorders allergic and asthmatic acti of molecules on target specific sites to strengthen mechanism th the explore to on is emphasis The ASTHMATIC AND MITIGATIONALLERGIC DISORDERS MISSI I. Progress under Network Project 1.9.1 comp pharmaceutical some bel given are project-wise achievements significant with and themselves within ar laboratories CSIR world. the in drugs generic of to industry drug Indian nascent a to fillip needed anti-b inflammatory, analgesics, and cardio-vascular drugs anti-virals, anti-cancer, for as such drugs, technologies viable commercially and cost-effective and several molecular gene based targets developed. drugs were laid. Also diagnostic tools were devise drugs. Herbal drugs pr were innovative standardized and and pharmacop effective cost developed has CSIR PHARMACEUTICALS & DRUGS CARE, HEALTH 1.9 ehooit Ida,Msr CFTRI Ravishan Mysore (India), Technologists Dr and Food Scientists of - Association (2003) Prof. V. Achievement Industrial Subramanyan Award Mysor (India), Technologists and Scientists Food of Associati - (2003) Award Godhoo Laljee Smarak Nidhi Sciences Biomedical to Contribution outstanding of recog In Bangalore: (India), Chemists Biological of - Socie The (2003) Rama Award RaoP.B. Dr. Memorial 79 e claim with e claim with a view to mitigating receptor receptor (FceRIb) with asthma in emerge as the largest producer largest the as emerge d d and introduced in the market ceil, nigacm, anti- anti-glaucoma, acterials, ow: Moreover, CSIR is developing for a wide range of essential of range wide a for among others, gave the much olymorphisma, namely, a G/ a namely, olymorphisma, iinCFTRI nition e working in network mode network in working e al, immunological, genetical immunological, al, CFTRI e ocesses for several generic several for ocesses eial standard for Ayurvedic n o te rprtos / preparations the of ons d altps r being are haplotypes nd on Dr. N.K. Rastogi, N.K. Dr. on Dr. K. Srinivasan, ty ne. oe f the of Some anies. . G.A. im n 3’-UTR, in hism kar, ON
S&T Contributions CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 S&T Contributions in in the the gel size of 8.3 * 10 cm.10 * of 8.3 size gel the approximately and proteins pollen the of resolution 5 of range narrow A components. allergenic identify sequences peptide These homology to the known derived. allergenic epitopes been already s have regions) PROGRESS: effectiv for develop or etc. immunomodulators to and adaptogens promoters, is health as use project for the formulation(s) of aim basic The GLOBAL FOR PREPARATIONS HERBAL SCIENTIFIC NEWER II. than the untreated control mice challenged with all with challenged control mice untreated thethan signifi shows mice immunised peptide of suspensions indicates their potential to modulate the immune re h hmtlgcl aaees RC WC differentia WBC, –RBC, analys were time clotting and PCV ESR, heamoglobin, parameters hematological The generated using PHASE (version 2.02) for unrelated • • • • Asparagusracemosus: Polymorphisms Polymorphisms in the promoter and a re dinucleotide The Iso electric focusing conditions of of protein the conditions focusing Iso electric The Using PROTEAN program, 15 antigenic stretches (incl of marker compounds. marker out. carried being is determination local Microbial was done. was above extracts were also developed. also were extracts above HPTLC alcohol. aqueous with extracted and processed with with lo microbial for examined being are powder plant of Amritsar market were powdered and extract with aque Sida Sida cordifolia: longa: Curcuma monieri Bacopa monieri: Bacopa Evaluation of the promising peptides for immune res immune for peptides promising the of Evaluation POSITIONING curcumene, demethoxycurcumin IL4 saponins gene were genotyped by sequencing and genescan ana isolated and chemical characterisation of and triterpe chemical isolated Fresh collection from local area was made and was and extra made Fresh area from collection local The extract was prepared as per the set protocols. protocols. set the per as prepared was extract The Two commercial samples procured from New Delhi and Delhi New from procured samples commercial Two and and , , Bisdemethoxycurcumin 80 etla asiatica Centella sponses to Th1 type. The spleen patients and healthy volunteers. ergens/ antigens. ergens/ ubmitted in allergen databank. 200 spots were separated on separated were spots 200 s of HI were standardized to standardized were HI of s raig aiu disorders, various treating -8 pI was chosen for better for chosen was pI -8 ed. The extract is isolated for isolated is extract The uding T and B cell reactive ee olce i bulk, in collected were aty es proliferations less cantly sadrie herbal standardized e peat in the second intron ad. The extract enriched extract The ad. ous ethanol. The extracts ee hn okd for looked then were were determined. finger print profiles of profiles print finger ponses ponses luoye counts, leucocyte l lysis, lysis, respectively. noid noid glycosides n vitro in ct prepared. The content The model Database construction: PROGRESS: The aim of the project is to create and develop in- develop and create to is project the of aim The DRUG TARGET USING IN-SILICO DEVELOPMENT BIOLOGY IV. MASS the in completed. been has Sequenom multiplexing and Pooling analysed. been 40 of panel discovery SNPs on work phase Discovery PROGRESS thein country. of human health in and general predictive medicine of common diseases and drug response related genes, It is proposed to an build Indian SNP (Single Nucle PREDICTIVE MEDICINE USING AND SINGLE REPEATIII. • from proteases and are structural proteins.structural are and proteases from (http://www.expasy.org/cgi-bin/lists?ribosomp.txt) coll origin) chloroplast not and mitochondrial (not (http://www. database lists?peptidas.txt). SwissProt The negative dataset from includes collected were curated protease (Aspartic, Cysteine, Metallo, Seri for training the neural nets. The positive dataset includes Aminoacid frequency, Dipeptide frequency, Attributes: Allium satium, satium, Allium these plants was isolated from green young leaves u leaves young green from isolated was plants these were developed in case of case in developed were materi plant for fingerprints DNA plants. medicinal identifi their for markers molecular of development Fingerprinting: DNA area of bioinformatics. of area for professionals IT trained and qualified generate drug and toxicity predicting for tools new develop new software, which enable identification of therap prog design to biology; silico in using development POLYMORPHISM : Seven attributes were considered for identificatio namely ASFP-LVS-1 and ASFP-LVS-2. DNA from leaf ti leaf from DNA ASFP-LVS-2. and ASFP-LVS-1 namely Two datasets were collected, one positive and anot h mi proe f h DA igrrnig s the is fingerprinting DNA the of purpose main The Asparagus racemosusAsparagus 81 includes non-redundant, manually all the ribosomal protein sequences ne, Threonine) sequences, which house capability in drug target drug in capability house ected form Swissprot database Swissprot form ected and two accessions in case ofcase in accessions two and otide otide Polymorphism) database & & drug response in particular Moments of charge, Multiplet which is in the larger interest that are completely different eutic eutic targets; to design and pursuing research in the in research pursuing sing CTAB method. CTAB sing response in silico; and to and silico; in response ape i 4 ee has genes 24 in samples als of 8 different species different 8 of als cation and protection of protection and cation rammes for developing for rammes RA sse using system ARRAY expasy.org/cgi-bin/ n of proteases which her negative ssue of
S&T Contributions CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 S&T Contributions the large scale culturing and storage of these orga these of storage and culturing scale large the a vaccines, making for and proteins genes candidate ne develop to is facilities new these of thrust The and five biosafety level 3 (BSL3), where workbios state-of-the-art can one up set b to envisaged is It VI. INFECTIOUS INFECTIOUS DISEASE HANDLING, STORAGE AND RESEARC VI. con its to notdue is cysteine of effect inhibitory stra type wild the in as same the were cysteine and to homocysteine. However, even in this strain the i This (str3D). deleted cystathionine to cysteine of added exogenously to yeast strain that had the gene conversionhomocysteine, to its to due is cysteine To homocysteine. of addition exogenous on profile DrosophilaModel: PROGRESS: th of understanding better to providing addition in for development i of new drugs by 2-3 years to from the envisaged is It technologies for new drug development, which will r drugs/chemicals. of develo evaluation drug new of process the influence to aims It ANIMAL MODELS AND ANIMAL SUBSTITUTE TECHNOLOGIES V. done. was checking quality and prepared were frequ Dipeptide frequency, (Aminoacid modules three frequency, Euclidean distance, hydrophobic distance fly as an anxiety model. asanxiety an fly more akin to anxiety, it was considered prudent to negative startle-induced a in response enhanced an activity was ever observed various under treatment caused withdrawal an increased negative geotactic r an established agent to induce seizure m and anxiety. mammalian In Drosophila. in alteration behavioral valpr gabapentin, atha compoundas emerged finally pentylenetetrazol ethosuximide, tetraethylammonium, pent strychnine, namely, agents, anticonvulsant and Yeast Model: FACILITY Yeast is being used as a model system to study the Out of eight chemically and mechanistically diverse mechanistically and chemically eight of Out 82 version to homocysteine.to version afety level 4 (BSL4) or P4 facilityP4 or (BSL4) 4 level afety e done on exotic micro-organisms. strain could not could convertcysteine strain In Drosophila, pentylenetetrazol nhibitory nhibitory effect of homocysteine homocysteine and cysteine was cysteine and homocysteine nisms. w diagnostic reagents, identify reagents, diagnostic w further further evaluate the potential of responsible for the conversion e drug action and targets. actionand drug e , , iso-electric point out of which current current average of 12-14 years regimes applied, because and applied, regimes esponse. Since no seizure-like nd to develop technology for technology to develop nd test if the inhibitory effect of effect inhibitory the if test educe educe the average time taken in. Thus clearly, the growththe clearly, Thus in. geotaxis assay is seemingly is assay geotaxis t brings about lasting long a t brings mn ad oiiy safety toxicity/ and pment lnttao, pilocarpine, ylenetetrazol, odels, pentylenetetrazol is pentylenetetrazol odels, ency, Moments of charge)of Moments ency, toue state-of-the-art ntroduce ae n vigabatrin, and oate gene gene expression convulsant H fumigatus further understanding of the biology of fungus. of the the of biology understanding further specific and sensitive a facilitate would antigens pro allergenic of Availability analysis. search the uiau. LS (BAT) nlss f el identi newly of analysis (TBLASTN) BLAST fumigatus. development of peptide-based vaccines against ABPA. against vaccines peptide-based of These development anergy. peptide-induced and count eosinophil histopa dec lung in ratio, eosinophils of infiltration IgG2a:IgG1 reduced specific increased by seen as of allergens/antigens showed A.fumigatus promising mice i.e., peptides administration (i.n. and i.p.) mode murine using ABPA, from protection in efficacy eva were fumigatus, Aspergillus of allergen/antigen terminal N- from derived mer) (6-11 P1-P5 peptides blood eosinophilia, pulmonary infiltration, and spe and infiltration, pulmonary eosinophilia, blood T sections. lung the in eosinophils and lymphocytes eosinophi blood IgE, and IgG Afu-specific of levels T concentrations. twoat different mice theto ABPA of pulmonary hypersensitivity were examined. rMBL w approach: (ABPA): Prophylactic potential of Aspergillus peptides agai peptides Aspergillus of potential Prophylactic PROGRESS: To facilitate facilitate To TBVACCINE NEW below: highlighted the of Some also. mode non-networking in networking activities in working from apart laboratories, CSIR achievements Scientific under Non-network pr 1.9.2 new new to fiv twenty of identification the to led spots 33 of number of proteins and specific IgE immunoreactive out of 36, 92 and 134 proteins respectively. Third filtrate fractions protein shows 18, 48 and 65 spec 1st, of sera) pooled patient ABPA (with immunoblots tuberculosis Administration Administration of rMBL in a murine model of allergi dniiain f oe alresatgn o Asper of allergens/antigens novel of Identification A. A. fumigatus The effects of exogenous administration of human rM whole genome shotgun assembly showed good homology good showed assembly shotgun genome whole h cmaaie nlss f -Egl (CBB-stained) gels 2-DE of analysis comparative The H37Ra, H37Ra, n vitro in proteome database and six were already known aller . aurum M. screening, models using nonpathogenic nonpathogenic using models screening, and virulent virulent and 83 . tuberculosis M. followed followed by mice sensitization with nst ABPA murine models murine ABPA nst week culture filtrate had maximum e proteins, nineteen of which are which of nineteen proteins, e ific ific immunoreactive IgE proteins diagnosis, immunotherapy and immunotherapy diagnosis, teome and 19 novel allergens/novel 19 and teome ils uiau uig proteomic using fumigatus gillus thology, decreased peripheral decreased thology, c bronchopulmonary aspergillosis proteins. MALDI-TOF analysis he ABPA mice exhibited high exhibited mice ABPA he cific Ab levels considerably. levels Ab cific reatment with rMBL lowered rMBL with reatment luated for their prophylactic their for luated i, xesv iflrto of infiltration extensive lia, scientific achievements areachievements scientific as intranasally administered esd pcfc g levels, IgE specific reased results results peptides with P1-P3 2nd and 3rd week culture week 3rd and 2nd ls. Prophylactically treated Prophylactically ls. major a 1, f Asp of region ogrammes oe cry hi R&D their carry mode, tde my ed o the to lead may studies 3R a ts strains test as H37Rv fied proteins with with proteins fied BL BL in a murine model . bovis M. n seii IgE specific and supporting : : BCG, BCG, gens of A. Synthetic M. A.
S&T Contributions CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 S&T Contributions potential molecules against virulent strain of strain virulent against molecules potential ramn pro wt cmlt seiiain Secon sterilization. complete with persiste period against treatment active be to expected is drug candidate for validated being inf currently is murine and developed experimental An screening. throughput in flavin dehydrogenase (inisocitrate vivo for expressed assays new protein) ha addition, In inhibitors. been has laboratory HTS in available dehydrogenase crystallin alpha resistance), isoniazid for (target also also of devoid any estrogen agonistic activity at u antiosteopo better a being to addition In rats. of of down-regulation ovariectomy-induced TGF b-3 expr for cell viability. Assays against select defined defined select against Assays viability. cell for developed and adapted to throughput screening along fluorescent green and luciferase firefly expressing as I ihbt bn mro drvd -S ad RAN and M-CSF derived marrow bone osteoclastogenesis inhibits It rats. (BMD) and mineral content in ovariectomized adult a extracts of a species active against against active species a of extracts selected found for active haveCDRI molecules been molecules have been subjected to 3 at active molecules, of selection to has mode HTS bones bones parathyroid hormone (PTH)-induced resorption of agent antiosteoporosis novel a identified has CDRI ANTIRESORBING AGENTS potential. antithrombotic anti-oxidant and ant its to due be to seem HM of effects anti-stroke found was to be quite safe thein pharma regulatory has also been demonstrated MRIby studies. The HM there was an enhancement in GSH the intra-cellular also a exhibited cytoprotective effect as the MDA l It was very effective in reversing the behavioural the area of infarction but also reduced edema owing model, and a dose of 500 mg/kg was effective upto 8 The HM at the dose of 250 mg/kg provided significan CDRI has developed an Herbal medicament (HM) for tr STROKEOF TREATMENT FOR (HM) MEDICAMENT HERBAL fi been patenthas international an and development in vitro in . It prevents ovariectomy induced decrease in bone bone in decrease induced preventsovariectomy It . n vitro in n cnetain eedn mne ad prevents and manner dependent concentration a in in in vitro M . . tuberculosis 84 cytotoxicity assays using VERO Sixcells. M. tuberculosis M. targets viz., viz., targets deficit deficit produced by the stroke. It terine/endometrial level. It level. terine/endometrial does have been identified for further for identified been have (agt o ltny, isocitrate latency), for (target e rosis agent than raloxifene, it is it raloxifene, than agent rosis evels returned to basal level and lyase (targets for latency) and latency) for (targets lyase ve been developed for induction protein as reporters have beenhave reporters as protein i-apoptotic, anti-inflammatory, i-apoptotic, to its anti-inflammatory action. 45 s well as retired breeder female 0%. 0%. The HM not only reduced cology cology in studies Therodents. level. level. Its anti-stroke potential Ca from prelabeled chick fetal µg/ml or lesser doses. These doses. lesser or µg/ml t protection in ischemic stroke further development. Herbaldevelopment. further on the basis of inhibition in inhibition of basis the on led. t atra n sotn the shorten and bacteria nt even even at effective dose5-fold with the Alamar Blue assay dary dary used for screening of theirof screening for used cenn. h nw drug new The screening. ession in lumber vertebrae eatment of cerebral stroke. cin oe hs been has model ection n vitro in M. tuberculosis M. (H 37 marrow density marrow Rv) in the non-the in Rv) L induced KL cenn of screening ahpC to be stable when stored at temperatures up to 60to up temperatures at stored when stable be to of any devoid was molecule cytotoxicity target and highly rats. This female adult cholesterol in total breast DMBA-induced cancer and inhibits ovariectomy a estrogen significant exhibits but beta, and alpha human purified to binding competitive any show not severity of ulcer. The anti-inflammatory and anti-o and anti-inflammatory The of ulcer. severity kD reduction of (92 MMP-2 activity, which strongly proMMP-9 correla of upregulation significant exhibit Indomethacin healing. and ulceration gastric acute IICB has studied the regulation of MMP-9 and -2 act ULCER GASTRIC CURCUMIN (HALDI) IN PREVENTION OF INDOMETHACIN-INDU NIO.by patented and tomolecules lead twocommercialize d anti-malarial NIO and M/s Shreya Life Sciences, Mumbai, recently FROM MUSSELSGREEN ANTI MALARIAL LEAD MOLECULES cells. cancer breast with molecules Liposomes are fatty vehicles that can carry d anti-cancer of set a gluing chemically by breast the created CCMB with collaboration in IICT LIPSOME SEEKING CELL CANCER BREAST Goa) technology has recently been transferred to an Indi this of by World identified Health Organisation for (WHO) i potentiality The tuberculosis. and malaria m and sensitivity greater has assay The conditions. rapid is all above and non-invasive cheap, is assay drop of blood Only a VL. diagnose can successfully biomarke leishmaniasis patients, which this can detect VL p even un of of expression development of erythrocyte assay binding to over monitor erythrocytes on The (glycotype) leishmaniasis. biomarker specific In search of a novel biomarker, IICB has identified A BIOMARKER FOR THE OF DIAGNOSIS VISCERAL LEISHMANI 85 cost-effective, easy synthesizeto cost-effective, the increased presence of disease an company (Zephyr Biomedical, o ivities in indomethacin-induced ntagonistic activity. It preventsIt activity. ntagonistic C. rugs rugs or anti-cancer genes to the and can be carried out in field outin carried be can and xidant properties of curcumin, of properties xidant te with indomethacin dose and der der field conditions. The assay organ damage and was and foundwas organ damage is required for this assay. The assay. for this required is eveloped from eveloped green mussels icvr hs en quickly been has discovery cancer cell seeking liposome seeking cell cancer signed signed a licencing agreement the statusclinical of visceral nml rs ratvt with reactivity cross inimal ts application global and the leae tmc extracts stomach ulcerated du cle haloperidol. called drug a estrogen receptor isoforms receptor estrogen increase induced in serum ) ciiy n moderate and activity a) hv hle i the in helped have r tet wt visceral with atients ASIS CED
S&T Contributions CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 S&T Contributions acids has attracted special attention especially in microarray etc. fabrication, In recent times, immob pharmaceuticals, microwave food processing, a diagnostics, bios of of biomolecul their Immobilized catalytic activity. demonstration time immobilization first of enzymes on an the activated polystyre is This AN ACTIVATED SURFACE THROUGH COVALENT BONDING RAPID MICROWAVE-MEDIATED IMMOBILIZATION OF ENZYMES I i It import plays MAO-B. dopamine, theof processing in as well act in metabolic in involved genes polymorphism the in polymorphism carried also these of 2 polymorphism patients CYP2D6, in carrying 3 polhad had genotype null of GST-T. Association data furth 5 in DRD2, in the that 6 polymorphism had revealed as RFLP and PCR allele-Specific using investigated, S-transf glutathione and (DRD2) receptor-2 dopamine monoamine (CYP2D6), 2D6 P450 cytochrome the as such important functionally of association and frequency wherein (PD), disease Parkinson’s studied has ITRC PARKINSON’S DISEASE ROTHEIR AND GENES IN SELECTED POLYMORPHISM GENETIC ameliorat activity and attenuationMMP-9through of Furthermo proces healing the accelerates It manner. dependent g blocks curcumin of re-epithelialization. administration intraperitoneal through curcumin by pe lipid depletion, oxidation. Denudation glutathione of epithelial cells during da preventing by model antiulce potent exhibits curcumin that show results an biochemical by examined is ulcer gastric induced eff possibilities, these test To both. or activity, ( species oxygen reactive scavenging through either an active component of turmeric suggest that curcum were immobilized on activated polymer surfaces in 4 and polypropylene for covalent of immobilization pr light-induced activation of inert polymers such as meth rapid and simple A required. is immobilization proteomics, and high throughput drug screening wher as compared to those obtained on untreated surfaces untreated on obtained those to compared as two-f than more into resulting reagent other any of 86 ect of curcumin in indomethacin- in curcumin of ect emerging fields such as genomics, mage of gastric lumen is reversed polystyrene (PS), 1 polyethylene, ensors, affinity chromatography, es es have versatile applications in ilization ilization of proteins and nucleic ne surface in 60s with retention er revealed er that revealed amongst the 4 in in may exert anti-ulcer activity old enhanced immobilization enhanced old r activity in acute ulcer in rat in ulcer acute in activity r ant role in the etiology of PD. of etiology the in role ant 5min at 37 otein otein ligands. Protein ligands ROS) or by regulating MMP regulating by or ROS) polymorphism in the genesthe in polymorphism says. Results of 16 PD cases PD 16 of Results says. . MAO-B, 4 in CYP2D6, and 3 and CYP2D6, in 4 MAO-B, ion of activity.of MMP-2 ion The methods. histological d ad rtcs ati ulcer gastric protects and s a case-control study of, the of, study case-control a e e stable, efficient, and rapid src leain n dose a in ulceration astric od has been developed for developed been has od ymorphism ymorphism DRD2 in while vto/ eoiiain as detoxification ivation/ rs-ht GTT was (GST-T) erase-theta oiain n protein and roxidation qie osbe that possible quite s xds B (MAO-B), B oxidase mdae covalent -mediated e bt oa and oral both re, 0 C without addition LE INLE NTO genetic role of STAT6 in asthma and atopy.asthma in and STAT6 role of genetic im be could repea haplotypes their yet, and as regions known regulatory are STAT6 of variants exonic no tota thelevel, with genotypes noshowed association, and the associated be to appeared locus R1 the at them and alone, the R3 locus has a thlarger effect appears that the R3 and R1 us loci together a play big generated were [R1_R3] haplotypes and 5'-unt genotyped, the in CA-repeat identified previously a and population. A novel polymorphic CA-repeat in the pr (STAT6) 6 transcription o of activator investigation and an transducer of results the reported has IGIB HAPLOTYPES AND ASTHMA IN THE INDIAN POPULATION AND ACTIVATORTRANSDUCER SIGNAL OF TRANSCRIPTION 6 The frequency distribution of alleles at the R3 loc The frequency distribution of alleles at the R1 loc 87 an the R1 Although locus. alleles ger ger role in asthma than either of R3 locus showed no effect. As oximal oximal promoter region [R1] srm muolbln E immunoglobulin serum l ih sha n h Indian the in asthma with asae rgo [3 were [R3] region ranslated te soito o signal of association the n otn i dcpeig the deciphering in portant plmrhss n the in polymorphisms t n PAE otae It software. PHASE ing us us
S&T Contributions CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 S&T Contributions the artificial eye to the implant.theto eye artificial the by developed also peg, alumina-based an desired, is tissues of the orbit and natural provide movement t over the glass/polymeric material is that they beco adv significant the of One complications. operative Ind in hospitals different at patients 50 than more implants orbital which porous hydroxyapatite-based fab and designed has CGCRI disadvantages. operative in vogue are made of glass or polymer. They are ass cosmetic and rehabilitation of the anophthalmic pat enucleatio after lost volume orbital the up fill to eye of the patient. The lost can eye be mechanicall from socket) the ththeorbit (eye toeyeball avoid When the eye of a person is damaged due to disease ORBITAL IMPLANTSBIOACTIVE INTEGRATED a burns cuts, compositionfor herbal and disorders; comp herbal anesthetic; local as combination herbal Alzh in enhancer memory as composition herbal novel arthritic herbal composition(s); novel herbal combi plants and the products; dadi ka enzymat batua: herbal stable reci and novel Tobacco; to antidote an as name formulations herbal modulator and anti-allergic herbal formulation(s); several developed has NBRI FORMULATION AND BIOLOGICAL PHARMACOLOGICALLY ACTIVITY HERBAL human phase trials.II undergoing is IICB of Institute National the with effort collaborative toxicological safe completely be to found been also st animal in protection full give to found been has Thi technology. DNA recombinant using toxin cholera a vaccine capable of theonly candidate elaborating by a novel IMT following strategy in an which aviru of first anywhere its vaccine, thein This kind wor CHOLERAORAL FOR VACCINE RECOMBINANT 88 e risk of life/the risk torisk of e life/the risk the other Cholera & Enteric Diseases and Diseases Enteric & Cholera pe; pe; antipyretic formulation; anti- n/evisceration to achieve betterachieve to n/evisceration ld USA outside ld constructedwas y replaced y an replaced by implantorbital ia with as yet no reported post- reported no yet as with ia anticigarette herbal formulation me invested with fibro-vascular nation for the treatment of piles; ient. Orbital implants currently immunogenic B subunit of the udies and completely safe has safe completely and udies antages of these Hap implants Hap these of antages ociated with a number of post- o o the eye. greater If movement or or injury, the surgeon removes nd wounds. nd lent lent strain was converted into have been clinically tried in tried have been clinically y hs atclr tan a strain, particular This ly. CGCRI, is used to connectto used is CGCRI, ic antioxidant system fromsystem antioxidant ic sto fr gastrointestinal for osition s candidate vaccine which vaccine candidate s ie’ odto; novel condition; eimer’s iae to aite of varieties two ricated y a oe immuno- novel a ly: 1.9.4 Recognition Recognition & Awards 1.9.4 Kishore Vaigyanik Protsahan RICD Human Resource Development 1.9.3 students of Science, Engineering and Medicine strea Medicine and Engineering Science, of students Gold Medal Gold r.JR ai rto o adoPloay D 2004– Disease Cardio-Pulmonary for Oration Vakil J.R. Mrs. Russia. Foundation, Partnership Scientific from Medal 2004 Honorary 2005-2006 (India) Chemists Biological of Society President, Russia Foundation, Partnership Scientific theby Collaborations International Scientific and Young Scientist Award by Indian Society for Mr Parasitology CDRI Society for YoungIndian by Scientist Award Allahabad (2003-04) from Award National of Academy Sciences, Scientist Young Memorial Bacchawat B.K. Prof.
o t otiuin oWrdSine CDRI Science World to contributions its for
by Association of Physicians of Indiaof Physicians of Association by Hydroxyapatite-based integrated orbital implants, d Evisceration Model Evisceration
Yojna programme was conducted with aim to attract 89 eveloped by CGCRI nceto Mode Enucleation ms to take career in research. in career take to ms CDRI Gupta, C.M. CDRIDr. Dr. A.K. A.K. CDRISaxena, Dr. Dr. P. Srivastava,Dr. r. r. A. CDRIGhatak, . R. Vatsyayan,R. .
S&T Contributions CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 S&T Contributions excelling in thesen through areas and both in network excelling a skills local using payments flexible and rigid of for its contribution to the roads sector through de these assessmentof integrity the in and etc. ships l rise, high as structuressuch complex and special in elements have CSIRspecialized laboratories engineering, structural optimal standardize to industry components have g developed innovative and building covering technologies c to from foundations right constructionactivities and techniques developed CSIR CONSTRUCTION & HOUSING 1.10 expertise in applying these sensors to real life pr life real to sensors these applying in expertise and physical properties of the materials used in th integrity, environment and behaviour of structures, the i of acquisition valuable ca sensors, which allows degradation health monitori health of method One failure. catastrophic structural of detection Early DESIGN AND OF ANALYSIS HEALTH SPECIAL ASSESSMENT II. done. been also has been done. Characterization of coatings, long-term replac 5% and controlled i.e. of M30 strengthabout Wall putty and Red iron oxide has been developed. C PROGRESS: country. whic materials building conventional the supplement p coatings, sealants, wood substitutes, composites, conc cement/ boards, tiles, blocks, bricks, as such bu alternative cost/ low develop to envisaged is It NEW DEVELOPING BUILDING CONSTRUCTION MATERIALS AND I. below. presented achie The projects. network three operating is CSIR Progress through Network projects 1.10.1 STRUCTURES INCLUDING BRIDGESINCLUDING STRUCTURES TECHNOLOGIES 90 signs and constructions techniques oblem. structures. CSIR is also known also CSIRis structures. onstruction equipments. Newer equipments. onstruction e e structure. This would develop nformation about about the nformation structural without damaging the chemical ong span, suspended, offshore, suspended, span, ong corrosion resistance assessment aints, pigments etc. etc. replace/ to pigments aints, nd material resources. CSIR isCSIR resources. material nd rete products, fibre reinforced fibre products, rete making design and analysis of analysis and design making ement of cement by flyash has flyash by cement ement of oncrete mixes for compressive on-network mode.on-network ng is by the use of fibre optic fibre of use the by is ng ilding construction materialsconstruction ilding vements during the year are year the during vements h are in short supply in the in supply short in are h I te ra f structural of area the In . reatly helped the helped building reatly hl i peeto of prevention in help n h woe au of gamut whole the Advanced analysis and design methods for steel fram steel for methods design and analysis Advanced Materials for special road application Studies on fatigue and fracture behaviour of piping of behaviour fracture and fatigue on Studies Construction. Austr the by recommended problems benchmark fifteen formula The developed. was frames steel of analysis beam element for formulations Bernoulli the d large PROGRESS: have been investigated. been have dif of properties emission Noise prepared. been has vari on report state-of-the-art A material. sorbing which developed been has concrete bituminous porous and hilly in roads of maintenance and construction High performanceHigh materials for construction and rep PROGRESS: etc.systems measurement traffic for models purposes, drainage systems, road management systems cons to techno reference with edge infrastructure road cutting required the provide to aims project The NEW AND IMPROVED ROAD TECHNOLOGIESIII. analy pushover 3D in involved efforts computational t minimizes greatly It history analysis. time namic w validated is procedure The diaphragm. floor ible s asymmetric horizontal of performance the evaluate Pushover analysis:Pushover tosufficient havealso found crack is through-wall resid The growth. crack through-wall and initiation for the pipes. pipes The tested have shown that the amplitude stress cyclic The crack. through-wall and obtained testsfrom fatigue anal bending were under data for 15 carbon steel (SA333 Grade 6) pipes havi measuring measuring quality, riding Sand patch test method fo P British strain, and temperature for sensors using destructiv Non Deflecto-meter, Weight Falling using been have fibres various concrete, using ash concrete reinforced fly volume differ high of concrete, length) in performance m 30 10- about (each stretches A frame-by-frame pushover analysis procedure is dev is procedure pushoveranalysis frame-by-frame A : : To To develop custom tailored special materials for 91 components: components: air of pavements es: ng circumferential surface crack he complexity in modeling and modeling in he complexity margin against SSE loading. SSE against margin re is sufficient margin re is margin sufficient crackfor u nieasrig materials absorbing noise ous r r measuring texture depth etc. truction materials for specific for materials truction ferent types of road surfacing typesroad of ferent ual strength of the pipes after pipes the of strength ual endulum Tester, Dipstick for Dipstick Tester, endulum eformation and eformation and post buckling and stress ratios were varied were ratios stress and ysed ysed to crack study initiation tions were calibrated against calibrated were tions desert areas, a new binder – binder new a areas, desert etback buildings with a flex- a with buildings etback ad nDli n evaluated and Delhi in laid knmtclyeat Euler exact kinematically A n seiiain ie High i.e. specifications ent e Testing, Instrumentation -Instrumentation Testing, e sis. dy- nonlinear to respect ith ois o dvlpn the developing for logies , , information systems, and ih efrac fibre performance high is an excellent noise ab-noise excellent an is la Isiue f Steel of Institute alian Fatigue crack growth crack Fatigue : : experimentalFew eloped to eloped
S&T Contributions CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 S&T Contributions R-hbnswr a dsge ad eeoe te sol the developed ca and type house green of designed is which has distillationsystem, RRL-Bhubaneshwar MATERIALSPLANT AROMATIC FOR ESSENTI OF EXTRACTION FOR SYSTEM DISTILLATION SOLAR applications.use end of requirement the syste bituminous urethane The respectively. 3409-95 IS:1 by assessed further is functions Waterproofing r (DSC), Calorimetry Scanning Differential thermal, Th susceptibility. thermal reduced a and resiliency variable with bitumen urethanized prepared has CBRI Conventional bitumen is brittle at low temperatures ROOF OF WATERPROOFING FOR BITUMEN SYSTEM URETHANIZED coating formulated other to compared as efficiency polyurethane based finishing coat has superior prop system comprises of Epoxy-cardinol IPN resin based and acrylic Pi based paints were also used as binder. finishin as used was hardener polyamino-amide and along wi IPN resin Epoxycardanol Recently developed o with along pigments doixide titanium and silicate blank oxide, iron micaceous powder, zinc phosphate, us coats formulated were finishing and intermediate steel structures exposed to humid/saline environmen sy protective IPN Epoxy-Cardinol developed has CBRI STRU STEEL FOR SYSTEM PROTECTIVE IPN EPOXY-CARDINOL reference. thecementwith strengthimprovement in related are a as used slag) microstructural changes (40% resulting from enhanced cement rea commercial 80-85% containing sample the of strength The 70%. in an with increase to found was strength 2-day and commerc vis-à-vis strength in increase remarkable a Use formulations. cement toprepare mixed and mill cement strength. The slag activat and clinker were the range of 50 to 95% to Blas replace clinker Granulated in activated Portla mechanically used has NML STRENGTH CEMENT IMPROVED Scientific achievements under pr Non-network 1.10.2 92 nd nd Slag cement (PSC) for improved g g coat. It was found that coating ed ed using separately an attrition and fluid at high temperatures. ctivity of slag and densification primer and middle coat having erties and corrosion protection systems. is behaviour is confirmed by confirmed is behaviour is 580 and IS:1834-84 ASTM D- ASTM IS:1834-84 and 580 ing synthetic iron oxide, zinc oxide, syntheticing iron t. t. Paints to be used as primer, . m has been prepared as peras prepared been has m ial slag cement. Both 1-dayBoth cement. slag ial al o acmltn heat accumulating of pable ther additives and solvents. and additives ther in resulted slag activated of slag was comparable to theto comparable was slag elgcl n I: 1208-78. IS: and heological crease in slag content uptocontent slag in crease viscosity, adequate elastic adequate viscosity, epoxy resinth unmodified ogrammes ie clie magnesium calcite, fixe, stem for the protection ofprotection the for stem t Furnace Slag (GBFS) in (GBFS) Slag Furnace t mne polyurethance gmented t s salse that established is It r tl o the of still ar AL OILS AL CTURES S il fr irnla n Lmn rs 8% n 8% re 88% and is quit economics of pointyield level this of view 80% grass Lemon and Citronella for yield w a in condensed is and system ducting adequate via vapou water plus oil The water. and materials plant ar trays The absorbers. as act to black Chrome with dist the of trays removable of numbers four the and The arrangements. mirror appropriate through energy has been concluded that two Blocks of the station w structu the on Based planned. is station new a when detailed wind tunnel studies sensitive are recommended in is sim structure the that shows analysis The struc out carried has SERC years. fifteen last the the original design life of ten years, it has alrea ‘Maitri’ is the second Indian Station in built Anta ‘MAITRI’ IN ANTARCTICA INDIAN OF STATIONTHE SECOND STRUCTURAL ASSESSMENT Front view of Maitri station Solar Distillation Unit 93 dy dy served as a permanent station for rctica rctica during 1988-89. As against e profitable as the fuel cost as fuel the e is profitable nil. tural assessment of the ‘Maitri’.the of assessment tural arrant arrant immediate replacement. o yai wn ato and action wind dynamic to ral assessment carried out, itout, carried assessment ral e used to hold the aromaticthe hold to used e r from the still are collected are still the from r ulated ulated boundary layer flows illation system, are painted are system, illation ater-cooled condenser. The condenser. ater-cooled inside surfaces of the stillthe of surfaces inside pciey Fo techno From spectively.
S&T Contributions CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 S&T Contributions the boundary layer wind tunnel of SERC, under simul usin fabricated was 1:100 of scale geometrical a to model rigid A generator. frequency a and spindle a The pressure calibrator model (PCM) consists rectan of a an on responses wind-induced of determination SERC has designed and fabricated a new pressure cal A RECTANGULAR TALL BUILDING MODEL CALIBRATED RESPONSE FOR MODEL PRESSURE WIND-INDUCED foundations and structures in confidence self-compact and placement easy including concrete, Studies that strevealed due to advantages several off and cracks of number width, crack pattern, crack u characteristics, syste deflection load as loading such behavior point two a using flexure, static for 3000 X 400 X 150 size of beams concrete reinforced el s oiotl ebr (em) ee at n th and cast monotonic were (compression (beams) and tension) and members dynamic loa horizontal as well verti Full-scale materials. available locally using ingredien sel the its develop to of tried has SERC characteristics. proportioning careful requires SCC maintaining homogeneity and gets compacted without sections, complicated congested around steel reinfo through flows freely (SCC) concrete Self-compacting CONCRETE SELF-COMPACTING View of crack in column 94 . cal structural members (piles) as (piles) members structural cal air chamber, rubber diaphragm, g acrylic material and tested in tested and material acrylic g ltimate load carrying capacity, carrying load ltimate f-compacting concrete mixtureconcrete f-compacting ered by by ered SCC over conventional rcement and accessories while ibrator model for experimental mm were also cast and tested and cast also were mm of a tall rectangular building rectangular tall a of t eaut te structural the evaluate to m ated ated open terrain conditions. dings structural elements having elements structural an i cnrt ad steel. and concrete in rains o, t ol b ue with used be could it ion, gular tall building model. building tall gular the need for any vibration. s o civ te above the achieve to ts pl bhvor under behaviour pile e
was evaluated. Highly S S ON SERC CRRI CBRI Human Resource Development 1.10.3 responses. developing an empirical mathematical model for pred results The condition. isolated an in scale) (1:300 mode aeroelastic an on as well as row a in arranged Also evaluated. were chi steel outsix on carried been had investigation points different at s the pressures and circumference and height the along levels a mean of variations the data pressure the on Based • • • • • • • • Society Ltd., which contained 27 invited papers. An papers. invited 27 contained which Ltd., Society Base Cement volume b out brought a special as workshop thewere Performance 200 January 5th High and 4th on organised on was Composites Workshop Indo-US An Serv Engineering November 2004.1-5, Rural of Engineers the for Safety’ ‘Contact Management, Transport Planning and Policie 2004 2-6, August during contractorsPWD Tripura of Road Rural of Construction Maintenance and ‘Design, at Lucknow Services, 5-9, 2004 Engineering Rural of of Engineers Maintenance and Construction Design, ‘Planning, 14-30, 2004 A Foundation Course of Highway Engineers of IRCON a 16-17, April during Jaipur at Ltd Lloyd PunjM/s of ‘Design, Construction and Maintenance of Bituminous i Construction” & ResistantDesign “Earthquake Management “Pest on organized Programmes Training Workshop of Rural thefor Bui A Executives National 95 of this study will be helpful in helpful be will study this of mney models of equal diameter equal of models mney nd rms pressures at differentat pressures rms nd iction of across-wind forces/ l of a cooling tower model, tower cooling a of l ail orlto between correlation patial 2004. International Conference International dtie wn tunnel wind detailed a s, s, Environment and Road lding Centres organized. lding Roads’ for the Engineers y the American Ceramicthe American y s’ for the Engineers and Engineers thefor s’ cs Lcnw during Lucknow ices, 5. The proceedings of proceedings The 5. t Gurgaon during June ua Ras fr the for Roads’ Rural RI uig July during CRRI Bidns and Buildings” n Concrete d
S&T Contributions CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 S&T Contributions Ayurveda Phase II: Phase Ayurveda work in work mode.Network ini major the of One possessed. knowledge domain of thederive greater benefits from the rich data and society powering the current century, CSIR laborato IT the in growth explosive inevitable the Realising PRODUCTS & DISSEMINATION INFORMATION 1.11 • et i te ae omt n lnugs s n h ca the been transcribed and 9,000 formulations in have been s as languages and Approximately 35,000 formulations format have been identif same the in texts wil formulations 77,000 of transcription the system sy Unani include to diversified gothas TKDL the of French, Spanish German, and Japanese, patentin app from 14 authentic Ayurveda texts five in internatio c Ayurveda phase the of TKDL first completing After PROGRESS: digit application patent retrievable and accessible w country the of knowledge codified The bio-piracy. t on thro examiners patent to available these making and database a creating F German, English, by are that languages international domain public in exists o misappropriation prevent to envisages project The COMPREHENSIVE TRADITIONAL DIGITALKNOWLEDGE I. Progress made under projectsNetwork 1.11.1 transcribed were included in the database. More tha More database. the in included were transcribed addition to interaction with scientists. with interactionto addition under CSIR-DAAD Exchange programme a and delivered Prof. Dr. Ing. Balthasar Novak, University of Stutt delegates. ( Structures conf The 2005. and January 8th to 6th during Composites organised Concrete in Advances on OUETTO N LIBRARY(TKDL) DOCUMENTATION AND Images of all the multiple references of 36,000 fo 36,000 of references multiple the all of Images 96 information information base and the update al format. al nal nal languages, namely English, l be carried out from 42 Unani42 outfrom carried be l gart, Germany, was with SERC canned canned from the original texts. ries ries have evolved strategies to sector and knowledge based knowledge and sector stem of medicine also. In this In also. medicine of stem rench, Spanish and Japanese and Spanish rench, ied, ied, 17,000 formulations have ughout the world to preventto world the ughout f traditional knowledge that knowledge traditional f lication lication the format, activities overing 36,000 36,000 formulations overing n 13,500 formulations have formulations 13,500 n ill be converted into easily into converted be ill tiatives towards this is to is this towards tiatives erence attracted over 250 over attracted erence e f KL Ayurveda. TKDL of se i kolde n five in knowledge his series series of lectures, in CC-00 was ICACS-2000) rmulations oras Tanr - riig rgas t locatio 6 at programs training - Trainers journals. gemn md wt Ms leir cec t e-acces to S T & S maintained. Science is journals 550 of subscription Elsevier M/s with made Agreement PROGRESS: libraries. digital of evolution ac electronic of culture the nucleate To resources; the facilities for pooling, sharing and electronica CSIRTo provide accesselectronic S&T staff, to wor JOURNALS ELECTRONIC TO ACCESS CONSORTIUM III. project.the for planning and required Activities during the year focused on capacity buil PROGRESS: needs. adopt/adapt state of art technologies in digital li in calibres high of professional have to ultimately Metros; To contribute in preparing future scientist t access facilitate To etc.; banks, question books, areas of e-learning facility and access comprising engineeri & science postgraduates undergraduate, of reaching by development national for contribute To NATIONAL SCIENCE DIGITAL LIBRARY (NSDL) II. compe been has formulations of Transcription cates. been from identified the Ayurveda texts and they ha as many as 19 scholarly journals, covering all the all as many covering as journals, 19 scholarly NISCAIR has been making a significant contribution DISSEMINATION OF INFORMATION TO S&T COMMUNITY below: highlighted s the of Some also. mode non-network in society the d are laboratories CSIR projects network from Apart Scientific achievements under Non-network pr 1.11.2 respective labs to lab based users. organisin based lab to labs are respective programmes training trainers these of Monitoring of usage Statistics is being carried out 97 brary brary solutions suiting the national lly lly accessing the CSIR information on monthly basis. The participants curriculum-ware-text books, help o remote areas at level similar to similar level at areas remote o ding ding in terms of IT infrastructure major disciplines of Thescience. major disciplines s, s, researchers and engineers and cess with a view to catalyse the catalyse to view a with cess large numbers; To design and design To numbers; large taff of CSIR accessing 1200+ e-1200+ accessing CSIR of taff ld S&T literature to S&T literature ld strengthen to Indian science by publishing ve been checked for the dupli- ted for 2,700 formulations. 2,700 for ted s f SR as Organised. labs. CSIR of ns the un-reached, i.e. students i.e. un-reached, the elivering scientific output tooutput scientific elivering ng level located in far flung far in located level ng ignificant achievements areachievements ignificant tann porme in programme training g ogrammes ter oras Print journals. their s
S&T Contributions CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 S&T Contributions journals are: Journal of Traditional Knowledge Traditional of Journal Journal of Biochemistry & Biophysics (bimonthly), (bimonthly), (monthly), wide across the country. During 2004-2005, 2004-2005, During country. the across wide Science-Ki-Duniya, SCIENCE-KI-DUNIYA b was ‘Environment’ on issue special A publication. yearly), Plants Abstract are regularly on updated regularly are the www NISCAIR’s website: The exposure to workers. R&D contentsIndian aband and journals abstracting and indexing international an indexed are journals the in published papers The Physics Applied & Launched in 1964, in Launched REPORTER SCIENCE monthly), monthly), and circulated science journals, For the popularization of science among the masses POPULARIZATIONSCIENCE Vigyan Vigyan Pragati VIGYAN PRAGATI Scientific and Wildlife.Government of India of Year the biotechnology; country; the outbrought environmental were issues spec with on, co the throughout readership wide a enjoying India, popular languages English oldest the of one is This ie n h cuty Luce i 15, t s o ru now is it 1952, in Launched country. the in wide of Chemistry (sec. A(sec. Chemistry of (bimonthly Research Indian Journal of Radio & Space Physics Rights (JIPR) (bimonthly), Annals of Library & Information Studies (IJFTR) (quarterly), Indian Journal of Experimental Biology ), Indian Indian Journal ), of & Engineering Materials Scienc Journal of Scientific & Industrial Research Bhartiya Vaigyanic evam Audyogic Anusandhan Patrika Anusandhan Audyogic evam Vaigyanic Bhartiya is a monthly popular science magazine in Hindi tha (MAPA) (bimonthly), and Science ki Duniya (IJPAP) (monthly), (monthly), (IJPAP)
the quarterly popular science magazine in Urdu, rea Science Reporter ) (IJC-A ) Indian Indian Journal of Marine Sciences Science Reporter ) (monthly), (monthly), Indian Indian Journal of Biotechnology (Urdu quarterly). (IJTK) (quarterly), (quarterly), (IJTK) (IJBB) (bimonthly),
entered into entered its 42 (IJRSP) (bimonthly), Indian Journal of Chemical TechnologyChemical of Journal Indian 98 Indian Journal of Chemistry (sec. B(sec. Chemistry of Journal Indian Indian Science Abstracts (English monthly), (ALIS) (quarterly), (IJEB) Science-Ki-Duniya Natural Product Radiance Product Natural (JSIR) (monthly), NISCAIR publishes three well- science monthly published in published monthly science (monthly) rought out. rought nd Indian Journal of Fibre & Textile wrns dcae b the by declared Awareness ial focus water scarcity inial on hs rvd international provide thus year of publication 2005.in publication of year d abstracted in most of theof most in abstracted d stracts the of all periodicals nr. Fu seil issues special Four untry. Journal of Intellectual Property .niscair.res.in nn i is 54 its in nning (IJMS) (quarterly (IJBT) (quarterly), es (bimonthly),(IJEMS) Vigyan Pragati , Medicinal & Aromatic Indian Journal of Pure (ISA) t reaches far and (BVAAP) (half- (BVAAP) otne to continued
Indian Journal . (fortnightly). ches far and th er of year ) (IJC-B) ) ), ), Indian (Hindi (NPR) (IJCT) Indian Launched in 1984, SAMACHARCSIR etc. IPR, accomplish R&D to transfers, marketing, commercialization/ pertaining utilizatio news published NISCAIR missions foreign and abroad missions Indian through re information disseminates also it (2005), year 55 mas users, other and industry agencies/departments, organiz R&D other to Council the of accomplishments useful link among the various CSIR establishments a NISCAIR has brought out information to other S&T departments, universities, departments, to S&T otherinformation cons CSIR various the among link useful a as serves vario particularly to the R&D pertaining activities of news the various the labo covers which Hindi, in the encyclopedic publication Serie Sci-Fun Biotechnology Series (10), Foundations (25), of Biotechno Series Jubilee Golden CSIR viz. NISCAIR has brought out over 60 popular books in En BOOKSSCIENCE POPULAR manner. topic scientific current on information disseminate CSIR News CSIR NEWSCSIR villages.to cities from moves IT of knowledge Malayala Bangla, Marathi, Gujarati, Kannada, Tamil, language have been translated in different Indian l a subject various on books practical Simple-to-use, PROGRAMME LITERACY IT interviews and session.the Chandigarh, during NISCAIR theteam by conducted in held Congress Science 284). It gives overviews of the various sessions of sessions various the of overviews gives It 284). SCIENCE AND AND IN SOCIETY SCIENCE 21THE Hindi. in out brought been have , the fortnightly newsletter (ISSN 0409-7467) is in is 0409-7467) (ISSN newsletter fortnightly the , CSIR Samachar Science and Society in the 21 Golden Treasury of Science & Technology is now in its 22 ST 99 THE AHEADROAD CENTURY: nd ratories of CSIR and consequently year. It is a monthly news bulletin anguages such as Hindi, Punjabi, garding CSIR to other countriesCSIR other to garding n, sponsorships, collaborations, reas of IT published in English in published IT of reas the 91the logy logy Series Others(6), (9), and nd nd to communicate activities/ etc. i vr es ad attractive and easy very in s st tituents. It also disseminates also It tituents. () QSre() Vsa in Vistas Q-Series(3), (7), s Century: The Road Ahead glish glish under series,different s activities/programmes, us s media, etc. Running intoRunning etc. media, s in India. During the year,the During India. in , ru ec s ta the that so etc. Urdu, m, tos uieste, S&T universities, ations, st f mnn scientists eminent of Session of the Indian the of Session tended to serve as a as serve to tended et, technology ments, . . Also, 28 books (pp
S&T Contributions CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 S&T Contributions paras. Some of the studies carried out during the year and on issues that are important to the country and to s policy analytics of in capacity building engender generate to specifically studies undertakes NISTADS BY NISTADS STUDIES RELATED AND POLICY SCIENCE page translated 900 over and request on English, to from S&T documents of translation provides NISCAIR SERVICESTRANSLATION combinatio any and country, date, publication date, ap subject, or code subject number, patent name(s), date title, from keyword(s) including parameters application various The number, country. and code, classification international application number, patent applicant( title, patent comprises: database the in 1975-2002 during India in granted patents 52,624 on INPAT is a bibliographic database, compiled by NISC INDIAN PATENT DATABASE (INPAT) (on pharmaceutical companies, clients crude drug for dealers, stude identified were samples drug crude samples drug crude lit related and of samples the studying by genuineness identification involves This PROGRAMME SERVICES CONSULTANCY Zir Vermiculite, Talc, & Steatite Weasels, Turtles, Terminalia, Zea, Vigna, Solanum, Zingiber, and mineral entries within the alphabet R to Z. The atclry n h cret lbl rn t incorpo to a mainstream. proprietary trend the into systems used global India current of the in resources particularly mineral and animal plant, The Wealth of India Raw MaterialsRaw India of Wealth The THE OF WEALTH INDIA The fifth and final volume of the , is an encyclopaedic publication describing the describing publication encyclopaedic an is , First Supplement Series 100 Starfishes, & &Silk Tortoises Silkworms, the domestic science institutions. briefly provided in the following s) name(s), inventor(s) name(s), inventor(s) name(s), s) conium Minerals, etc. Minerals, conium ciences and to deepen skill sets skill deepen to ciences and important entries areincluded database can be searched by searched be can database s were produced. were s plication number, application number, plication n of the above parameters. above the of n AIR that provides information . The information on a patent a on information The . nts, teachers, and researchers. 237 year, the During erature. applicant name(s), inventor name(s), applicant ae rdtoa knowledge traditional rate novel research methods, to methods, research novel comprising basis) payment encompasses plant, animal various foreign languages foreign various n re t cek their check to order in a eeec standard reference a s pbiain date, publication , to domestic and global marketing initiatives. marketing global and domestic to ma that concluded Study out. pointed were materials a technology of upgradation including technolog craftspersons of building capacity to pertaining issues availability to the rural artisans, the handicrafts delivery including of re-designing of institutions cra interventions thein nature of action research sugg rural underta were traditional handicrafts for of upgradation technology skills improving to inputs inputs to the improving system of manuf traditional pertaining to improving the S&T wherewithal's of ru Studies conducted on areas of artisanal technology, INDIA RURAL POLICY FOR S&T highlighted. were commercialization facilitate to that large companies did well through networking. I barriers and how skills remained trapped to medium majo how bottlenecks, the remained skills and funds biotechnolo of commercialization on Study advances. what types of institutions of polici what and kinds such as nano-technology or the stem cell were exami technology areas. Biotechnology and information tec Several studies addressed Indian industrial issues INDIAN INDUSTRY & EMERGING HIGH TECH AREAS to technology patenthigh India.in areas from across Indian organizations need to be upgraded. Fo to be accomplished in the area of design patenting. is the most active organization especially filing p are major players in are patenting. Universities sl found was It insti organizations. university more and research involve to need policies patent however, w be to appears industry Indian impact. substantial pharm in patents product allowing ActPatent Indian o was It weaknesses. and strengths Indian indicated parti institutions generating knowledge domestic on activity, technological areas addressed and gaps th PATENTING PATENTING TREND Studies on patenting were employed to map trends, s trends, map to employed were patenting on Studies 101 or the system of production. Policy atents under USPTO. Much needs could improve the S& T resources owly owly entering in patenting. CSIR Similarly technological linkages at needed to be filled up. Studies ested ested how novel mechanisms of pertaining pertaining to the emergent high es could support contemporary reign organizations have chosen artisan clusters and on policies hnology including micro-areas ral India. S& T and managerial ncentives and policies needed acturing for example, acturing for or example, S& T ned ned to draw policy lessons on ell prepared for the changes,the for prepared ell that very few organizations few very that quality quality only. It was observed bserved that changes in the in changes that bserved cl eore fr h rural the for resources ical aceutical sector would have would sector aceutical jor thrust needs to be given be to needs thrust jor r technological risks posed risks technological r tpros r ein and design or ftspersons d cess o rdt raw credit, to accesses nd ken; and such studies and studies such and ken; education the from culars uin nml frs and firms namely tutions y hwd o ces toaccess how showed gy ectoral and institutional and ectoral
S&T Contributions CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 S&T Contributions higher studies work for focussed projects. focussed for work studies higher NISTADS is running student practical training progr NISTADS Resou Human IT Courses; Sponsored IGNOU Programmes; h poet niae t cnoiae ed processes technologie lead develop to and gained; already leads on consolidate to standardization of technologies for bio resources envisages f project The ICI ofr svrl R porme to programmes HRD several offers NISCAIR NISCAIR Resource Human Development 1.11.3 I. STANDARDIZATION OF TECHNOLOGIES FOR BIORESOURCES STANDARDIZATION OF TECHNOLOGIES I. Progress made under projectsNetwork 1.12.1 coverage. i leather Indian the of development sustainable the L pioneering mounted a successfully had It sector. leather the for needed resources human the creating and goods, fashion colour forecasting export certif chemicals, value added specialty leathers, to computer aided d ne tanning to tanning, in operations chrome’ net of ‘no computerization and chrome’ ‘low to tannin pollution low and saving time appropriate to o storage to animals dead of flaying for techniques in the of stages all at been have inputs pioneering the leather industry to a modern, vibrant, environm the world. Through inputs of S&T and extension act Institute Central ofResearch (CLRI) Leather CSIRi LEATHER 1.12 (AIS Associatesh example, for Communication, Science and and to train and empower professionals in the field ); AND AND FROM LEATHER Education, Training and Translation Group (ETTG); (ETTG); Group Translation and Training Education, 102
rvd laesi opportunities leadership provide or or and from leather sector based s of Information, Documentation ication ication and not the least of all in fromstarting activities dustry’s ent responsive industry. CSIR’s amme where students pursuing s the largest leather institute s in theleather largest f skins, using ‘no’ or ‘less’ salt, ‘less’ or ‘no’ using skins, f eather Technology Mission for Mission Technology eather ivities it has been transforming esigns esigns for footwear, garments, ndustry with vast grass-rootsvast with ndustry industry and the R&D in the in R&D the and industry g and processing techniques, processing and g w techniques for generating for techniques w s for use of solid and other and solid of use for s ip in Information Science Information in ip o oenzto by modernization to n pout and products and rce Development. rce TrainingAttachment FOR n ete sco i T. hy ae en eevn i receiving been have They TN. in sector leather in state are connected to pollution control devices. T Today state. the in sector tannery the to solutions possi it made has industry with CLRI of partnership problems. environmental of account on crisis major i clae pout dvlpd y LI ae en c collagen been extracted was have constructed as CLRI gels and used by developed products collagen Six PROGRESS: applicat value high related and products biomedical as resources stock new bio feed biomaterials and fo CONTRIBUTION TO ENVIRONMENT Scientific achievements under Non-network pr 1.12.2 of of human fibroblasts. A potent lipase producing str standardized. chemicals or passing compressed air or adsorption b by sources odor of removal of Methods ammonia. and sulphid mainly are processes pre-tanning in odor of liquor and Reverse Osmosis (RO) system has impro been for system des A litres. 1000 to litres 1600 from the reduction of water 17000 from litres to 7000 li int develo has been water reuse of system hide/skin and recycling raw converting For achieved. been has A mobile chilling system has been designed. A ten-f PROGRESS: limit). mg/ 2100 to wastewaters tannery discharged of level technology secure develop to processing; leather in environmental risk; to develop technologies for red pr leather friendly environment technologies viable The project aims to design, develop and disseminate PROCESSING FRIENDLY LEATHER ENVIRONMENT II. developed. been has feed chicken utilization for method innovative An isolated. was After 1996, Indian leather sector and particularly particularly and sector leather Indian 1996, After 103 tres with being limiteddischarge here here are a total of 14 CETPs now old reduction in water discharge ain ain ucing ucing the consumption of water ved evaporation of saline soak saline of evaporation ved as a substrate for all functional tanneries in the in tanneries functional all through appropriate measures r use cosmetics,in agriculture, that of Tamil Nadu has facedhas Nadu Tamil of that y y activated charcoal have been options for reducing the TDS the reducing for options ocessing in India at near-zeroat India in ocessing of flesh into dog biscuits and biscuits dog into flesh of igned at lab scale. The sources ped by which it was enabled was it which by ped ions e ions (hydrogen sulphide) (hydrogen ions e Aspergillus niger l t rvd meaningful provide to ble liter (minimum acceptable (minimum liter h lsig n enduring and lasting The ogrammes crm tne leather tanned chrome o means of adding reactive adding of means pt o tcnlg for technology of nputs mecaie. Calfskin ommercialized. in in vivo MTCC 2594 culture
S&T Contributions CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 S&T Contributions y 7, hoie euto b 4% wtr ipt re (input) 20% volume sludge in reduction and water 35% by reduction 40%, by reduction chloride 67%, by in two tannery clusters in Tamil Nadu viz. Dindigul recycling of reliming liquor, of recycling pickle l sulf less saving, hair desalting, effective include (TDS) Solids Dissolved Total in pioneered has CLRI PROCESSING IN LEATHER CONTROL TDS on preparedness. environmental on impact an traceable emerged has It modernization. and upgradation PRODUCT DESIGN & DEVELOPMENT leathers. of properties organoleptic neg any render not does process the that found been method has been tested at semi commercial scale in dis wastewater The wastewater. pickling and washing CLRI has developed a process for near zero discharg ZERO DISCHARGE TANNING sides. both on 5 months without putrefaction or deterioration skin supply supply after between equilibrium bringing the envir gar in property insulation thermal studied has CLRI THERMAL INSULATION INSTUDIES GARMENTS Winter 2005-06 seasons was released on 8on released seasonswas 2005-06 Winter Col Modeurop The selected. were garments for colors f chosen were colors 20 totalof a outof 15 India. and textures has been presented. 400 leather/color 06 season held in June 2004 ‘Curtain raiser’ on the for the roundtable MODEUROP for the In preparation DESIGN AND FASHION FORECASTING increase this further. c year per designs 150 like figures registered have mode. development contract on as well as protection LI a iiitd esrs o eeo nw products new develop to measures initiated has CLRI A A Neem oil based preservation has been developed wi 104 th July 2004. July iquor. iquor. This has been implemented or shoes and 7 out of a total of 10 totalof a outof 7 shoesand or ide -enzyme assisted unhairing, assisted -enzyme ide season’s trends leather in colors urrently. There is an attempttoan is There urrently. and Pernambut. TDS reduction proposals were presented from s can be preserved by applying wet wet blue production and it has e wastewater by enzyme aided onment temperature and heat ments by measuring the heatthe measuring by ments Design outputs from CLRI from outputs Design reduction measures, which measures, reduction our Card for the Autumn/the for Card our ative effect on physical or physical on effect ative the2005- Autumn/Winter has been feasible. been has uto b 1-0, BOD 15-20%, by duction charge is 1litre /kg. This /kg. 1litre is charge on prnrhp with partnership going th shelf life of more than n se copyright seek and CLRI-Anna CLRI-Anna University collaboration. A total of 165 students underwent education in Leat w and of atlife the improving sectorquality aimed has been developed. been has implemented. Also, on-line status tracking system f products and a web enabled design solutions for pro cand challenged it to extending by physically added and a database has been for designed leather produc pro for courses on-line developing for design Basic PRODUCTSLEATHER FOR DATABASES suede.nappa>Goat nappa>Sheep (shee Fur insulation thermal of order decreasing in on suede apparels. and Based the study, typvarious apparel nappa cow in more be to found is insulation but than insulation thermal more has garment zipped lea all among that found was It temperature. source coatings etc.; and superconducting materials. superconducting and etc.; coatings glasses shielding radiation glasses laser finders, for glasses special composites; aluminium-graphite a whiskers; carbide silicon carbide, silicon bonded alloys, high performance industrial materials such streng high equivalent Kevlar a - Nalar composites, a such materials aerospace pastes; silver polymers, sil polycrystalline and luminescent phosphors for display, piezoelectric, h amorphous as such materials materials for in aerospace, defense and sophisticated role significant a played have laboratories CSIR MANUFACTURING& METALS MINERALS, MATERIAL, 1.13 • CLRI Human Resource Development 1.12.3 Technical education to varied target group has been Resource Developm Organizational & Human for Centre 105 or leather product manufacturers and sol-gel techniques for glass for techniques sol-gel and as silicon carbide, silicon nitride industrial industrial sectors viz. electronic her and Footwear Science under igh igh purity alumina, conducting ork group.target ork of this leaner s high density carbon-carbon density high s ducts manufacturers has been th fibre, aluminium – lithium– aluminium fibre, th es of leathers can arrangedbe ts. ts. A new dimension has been ducts design & development & design ducts idates. A database for leatherdatabase for A idates. ther types (expect suede) the suede) (expect types ther optical fibres, infrared range infrared fibres, optical h dvlpet f special of development the uiimmtl arx and matrix luminium-metal -ap)Cw nappa>Goat p-nappa)>Cow s among the selected nappa selected the among s carried out for the artisanal toned garments. Thermal garments. toned cn frie, gallium, ferrites, icon, ent (CHORD)ent
S&T Contributions CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 S&T Contributions the lowest Nb-doping, viz. La viz. Nb-doping, lowest the eval were properties thermal and electrical the and La RE’TiNbO n de n hs aes oh hog Ntok n Non paras. following in and presented is achieved progress Network through both areas these in edge an ap systems and now for the designing mine disaster management in for source principal the been has CSIR surface underneath and pillars in up locked coal of studies and efforts on subsidence prediction and co only of exclusion the (to mines coal in especially higher failure energy (10 -70 KJm2 prepared and to about 10 63 to 70% 5, theoretical 3, density. Th of (MLC) composites layer multi cast solid state processing of Ba(Mg of processing state solid 540 from shifted is peak resonance plasmon surface refractive index of the host (by increasing titania prepared on glass substrates and characterized by d Gold (Au) nanocluster doped films in SiO in films doped nanocluster (Au) Gold PROGRESS: advantages. financial and technological of terms to sectors strategic the also and industries Indian wo knowledgebase The nano-materials. functional and materials de like novel non-linear by optical materials, expertise date to up and knowledgebase strong materi on special customtailored based are devices a technology communication and information Advanced MATERIALS SPECIAL TAILORED CUSTOM I. Network Projects1.13.1 ige ae A e sre o La of series new A tape. single cm at 800at cm minor role in the marine mineral export compared to compared export mineral marine the in role minor deposits placer enriched maximum having of spite In CAPACITY MIN MINERAL PLACER FOR BUILDING COASTAL II. oxi of family this in reported far so value highest 2 Mo CSIR has made significant contributions to all aspe all to contributions significant made has CSIR 2-x 2-x Nb o C, which is nearly double that of the undoped mater undoped the of that double nearly is which C, 6 ceramics has been developed. Porous nano alumina p alumina nanoPorous developed. been has ceramics x O 9 9 where x = 0.4 were prepared by a citrate-nitrate co 2 Mo -3 1/3 ) than that (4.38 KJm 2 1.94 Ta Ta Mo Nb 2/3 2 O 106 0.06 )O 9 ae oie o te eea formula general the of oxides based O 3 3 2 and mixed SiO mixed and , Ba(Zn , 9 , exhibited a conductivity of 0.113 S/ 0.113 of conductivity a exhibited , bio-molecular electronic materials content in the film matrix) the Au heavy mining equipment). CSIR equipment). mining heavy des. ntrol have enabled the extraction remain globally competitive in competitive globally remain ese MLC samples showed much 1/3 ifferent ifferent techniques. Increase of als. It is envisaged generateto envisaged It is als. structures and water bodies. water and structures uated. The composition withcomposition The uated. -3 Ta lyrcniuain were configurations layer 0 other dominating countries dominating other ) of the porous nano alumina the country. CSIR is getting m o 0 m Poes for Process nm. 600 to nm rpit mn ventilation mine propriate , India continues to play a play to continues India , uld be needed by boththe by needed be uld 2/3 eoig e generation new veloping cts of mining operations, mining of cts nd ultra-fast processing ultra-fast nd )O ntok rjcs The projects. -network 2 -TiO 3 3 and RETiNbO and ial and this is the is this and ial mbustion process 2 hosts have beenhave hosts owder and tape and owder ING 6 6 and IV. BIOMINERAL PROCESSING FOR VA METAL EXTRACTION FOR OF PROCESSING BIOMINERAL IV. pat ten to patients 50 on successfully implanted and administered developed were implants dental coated developed the and being algorithm tested for obstac Autonomous Robot and of Mobile models Experimental PROGRESS: self-reliant becometo shape netmanufacturing near man in both expertise indigenous the upgrade to and adv of applications the explore to aims project The DEVELOPING CAPABILITIES IN ADVANCED MANUFACTURI III. through completed was deposits placer of locations Digitizat analysis. for collected were samples sand th and places many in to correlated out find the changes of beach profile done been has profiling Beach wa Nagapatinam and Karaikal including Velanganni to parts of Coastal out Tamil Nadu.carried been More have than studies 35 field km and stretc Geological PROGRESS: expor the from returns economic appreciable besides as India put would work this of output The mining. techno country’s of capability the enhance to aimed placers buried for especially technology processing development the through market export placer Indian that have lesser potential than There India. is a h was studied using mixed culture containing acidophi ore by varying parameters like pH, pulp density carried and were flasks shake in work bioleaching scale Bioleaching of lowgrade copper ore of Malanjkhand PROGRESS: (10 values metal of recovery for processing stream Bioleaching of uranium (UCIL, 0.026% U); Strain imp The project aims at bioleaching of low grade coppe FROM ORES AND CONCENTRATES WASTESAND CONCENTRATES AND ORES FROM 107 igh igh scope to improve the status of s due to Tsunami. andSediment h of coastal zone from Cuddalore r r ores of Malanjkhand (0.3%Cu); anced manufacturing methods manufacturing anced litres/hr capacity). litres/hr particle size. Leaching kinetics lic microorganism. The copper (0.3%) were made. Laboratory le avoidance. avoidance. le Hydroxyapatite . rovement; Continuous down- and offshore resources. It isIt resources. offshore and GIS environment. GIS o o bs mp o various of maps base of ion out using low grade copper grade low using out just after Tsunami in central in Tsunami after just oisi tefed f placer of field the in logies t potential.t a global leader in this field, this in leader global a . ufacturing automation andautomation ufacturing of indigenous mining and mining indigenous of Robocasting (2.5D) were (2.5D) Robocasting et. ria implants Orbital ients. udrdtie study. detailed under s erir rfls were profiles earlier e NG LUES
S&T Contributions CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 S&T Contributions of biomass. Preliminary studies showed that two str two that showed studies Preliminary biomass. of from isolated strain fungal Cu and gro U mines were aaees f mrhu PT hn im o crig g corning on films thin PZT amorphous of parameters layer of bearing specimen fro tri-metallic received to used been also has It tube. heater super exposed thick scale oxide used measure to and Labview using lsi nlss eecridotuig heterotroph using out carried were analyses Plasmid Uranium recovery d was more than 70% pulp in 30 days of pH, le like parameters varying by microorganism carried was leaching Uranium U) densit 0.02% pulp (UCIL a Uranium at days 50 in 40% around was recovery 300 and alloy 800. alloy and 300 following grades of steel: Carbon steel, 1.25Cr-1Mo behavio erosion to related grades steel the on data temperatur elevated at components boiler coal-fired ver first the is Components) Boiler in rate Erosion codes have been developed: . developed: been have codes behaviour on coal boiler fired components. predic The foll quantitatively to developed been phenomen have models and conducted been have studies Analytical by grain boundary engineering first phase of Thermo c enhancing For SET-UP. PORTABLE-BI a for made been o mechanica carried were measurements hardness and evaluation conventional and BIT using conducted been carbon medium steel, En 718, Inconel on Experiments PROGRESS: structures. scale full ECA of ECA; ev damage of simulation and Modelling surveillance; Signal and image processing techniques damage for a Qu sub-st for ECA materials; tasks; resistance of engineering techno planned following requisite the the through of implemented development The components; and rail wheels concreterailway and steel bridges, ind process and th of assets Infrastructural components; aeroengine petrochemical plants, power nuclear p and vessels Pressure components: following the of The project aims at development of technology for E CRITICAL FOR ANALYSISENGINEERING TECHNOLOGY V. and and Aspergillusflabus Software has been developed to measure the thin co thin the measureto developed been has Software have the potential to remove copper from aqueous s aqueous from to copper potential remove thehave EROSIM-1 (A Computer Code for the Prediction of Prediction the for Code Computer (A EROSIM-1 108 m m RDSO, Lucknow. Deposition way tracks; way Offshore structural -V -V , 2.25 Cr –1Mo, 12Cr-1Mo-V, ructural and and processes;ructural surface owing owing model based simulation ngineering Critical Assessment ur, the model incorporates the incorporates model the ur, measure the different coating different the measure sion of the code applicable to applicable code the of sion e transportation industry: e.g. industry: transportation e -mechanical treatment is over. ains such as as such ains wn toamount large generate es. On the basis of availableof basis the On es. aching. aching. Strain improvement. ssessment; Sensor device for ness ~ 400 micron of service of micron ~ness 400 olution & software toolsfor software & olution ipelines of the thermal and thermal the of ipelines ic ic steels and Al alloys have alloys Al and steels ut. Conceptual design has design Conceptual ut. te s pril erosion particle ash the t o 2% ilahn of Bioleaching 20%. of y as 77 n platinised and 1737 lass niy n pril size. particle and ensity Acidiphilium sre; ifae and Airframes ustries; omponent performanceomponent damage of antification lgcl mathematical ological ts. Microstructural test. l u uig acidophilic using out oy s ogt o be to sought is logy Aspergillus nigerAspergillus sri. The strain.. ating layer ating olution. an in minimum time. minimum in an out through industry Indian to services calibration trace for organized been have courses training Four PROGRESS: material. reference certified of dissemination and the country at a reasonable cost and in a reasonabl calibration and testing quality high providing for facilities test and calibration of Networking tics, Tempe Force, Length,; Current, & Voltage AC Energy, of Apex level in facilities calibration the followi surements for : Mass,; Luminous Intensity, Time; Ch projectThe aims at upgradation of the Units Base a quality bearing high concentration of C of concentration high bearing quality VI. UPGRADATION OF UPGRADATION SI BASE UNITS, NATIONAL STANDARDS VI. done been has fi sensorthe configuration for material Pt of conditions deposition film of Optimisation corning glass from a stoichiometric Pb(Zrstoichiometric a from glass corning CGCRI has developed a series of Cfullerene DOPED GLASSESFULLERENE below. given are achievements significant the of CSIR laboratories are carrying out R&D activities i Scientific Achievements under non-network pro 1.13.2 light and the hence limit can serve can as they a protector i.e. of properties laser d limiting optical These composites show moderate third order nonlinea Non-L as suitability their identify to studied were lower frequency.lower materials are also in useful generating light of hi intens of increase the with increases transmission, it that characteristics unique the by filters light DISSEMINATION DISSEMINATION OF CRMS AND TESTING LABORATORIES AND &PREPARATION & CREATION A OF OF MEASUREMENT CALIBRATIONNETWORK 109 60 and their nonlinear optical properties optical nonlinear their and 0.52 60 Ti -borate -borate glasses composites of optical 0.48 etectors. It differs from the ordinary ng parameters- Mass, AC Power & gher gher from frequency laser light of efcec o lmtn te light the limiting of efficiency s existing in 12 CSIR laboratoriesCSIR 12 in existing )O e e time; Preparation, certification n n non-network mode also. Some rnmsin f ih intensity high of transmission facilities to users in all parts of parts all in users to facilities emical Metrology: Upgradation inear Optical (NLO) materials. (NLO) Optical inear nd National Standards Standards nd National of mea- ity of the incident light. Such light. incident the of ity the country at minimum cost minimum at country the . 3 target have been optimised. been have target able and globally acceptable globally and able m t b ue a electrode as used be to lms r r optical properties and good rature, Ultrasonics, Acous- Ultrasonics, rature, grammes OF
S&T Contributions CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 S&T Contributions WATER MIST- AN EFFECTIVE AGENT FOR CONTROLLING OPEN OPEN FOR CONTROLLING AGENT MIST- EFFECTIVE WATER AN GeO the fire area resulting into creation of cooling ef cooling of creation into resulting area fire the along flowing while mist water the injected by away g heat the that is temperature the reducing in mist monoxide percentage came down to 93 in case of both The core was doped with different dopants like GeO like dopants different with doped was core The resin The dimension coating. was core-clad i Mol varied by proportions different deposition (MCVD) process and were fibres drawn fro in core the in dopants encountered in optical network. CGCRI has fabricate in multi-channel wavelength amplification for reduc wavelength pump stabilization, wavelength laser for and config (EDFA) amplifier fibre Er-doped different in applications in (FBG) grating Bragg optic Fibre (FBG) FOR WRITING BRAGG-GRATING FIBRE FIBRES SPECIAL after injection of liquid nitrogen (LN nitrogen liquid of injection after high-pressure high stability (HPHS) nitrogen foam. it whereas mist, water of spraying after hour) per temperature of reduction average The area. affected also reducing toxic gases, minimizing backlash and f open controlling only not for technique effective CMRI, after detailed investigation proved that wate IN UNDERGROUND MINES of Ge-Ge bonds indicating change in refractive inde refractive change in indicating bonds of Ge-Ge (E’) Ge viz., generation centre colour irradiation varied in different concentrations. It was observed ecn atr neto o HH ntoe fa ad L and foam nitrogen HPHS of injection after percent was maximum (89 percent) in case of water mist, whe 2 2 along with rare earths Er & Nd. GeO Nd. & Er earths rare with along In-fibre Bragg grating writing set up us 2 ). The reason behind the efficacy of water of efficacy the behind reason The ). 110 2 content within the core of fibre was fibre of core the within content fect. Reduction of CO of Reduction fect. center increases via the breakingthe via increases center that under the influence of laser ire in underground mines but mines underground in ire was 207°C per hour in case ofcase in hour per 207°C was r r mist infusion is safe and very n n the range of to10:125 22:125. enerated due to fire is carried is fire to due enerated ing problems of non-linearities But But the value was much below improving visibility in improving visibility the fire d d preforms containing suitable x in the fibre core.x fibre thein water mist and LN was found maximum (294°C maximum found was with the air current through current the air with provides practical solutions practical provides filtering and gain flattening gain and filtering reas reas it was 80 percent and 30 rtos ae on major found have urations 2, m the preforms with online B clr hmcl vapour chemical ecular 2 N O 2 3 3 epciey Carbon respectively. + GeO+ 2 , SnO , 2 generation 2 compared 2 , SnO , FIRE 2 + condition except the pH which was mai was which the except pH condition mist no substantial increase in H in increase substantial no mist decrease in the intensity of fire to the maximum ex water of application after processes combustion of to 85 after use of HPHS nitrogen foam. These findin were bioleached by bacteria and fungus viz. viz. fungus and bacteria by bioleached were of bioprocessing on studies extensive done has NML METALS VALUABLE EXTRACTION OF OF INDIAN BIOPROCESSING WITH OCEAN REFERENCE NODULES T.Thiooxidans, circulars Bacillus, T.Thiooxidans, and 32% Fe was recovered by by recovered was Fe 32% 98% Cu, 97% About conclusion. this supports biomass nonenzymatic process. Easy desorption of adsorbed m Fun size. mm 300 < of nodules seathe using density limit. No water gas found discounting the possibili the discounting found gas water No limit. mediated process. Upto 92% Cu, 73% Ni, 72% Co, 38% 38% Co, by 72% recovered Ni, 73% Cu, 92% Upto process. mediated of of H ciain nry curd o te idsouin o biodissolution diffusion the control leaching for model. Bioleaching by acquired energy activation controlled model in the temperature range 293 – 308 and 71%, 71% and 37% with sulphur. Bioleaching of t Co at 308 K in 60 days time and 2.0 pH was found as 2 concentration was recorded as 0.26 percent, which
Generation of water mist Bacillus circulans Bacillus A. niger A. at pH 2 in 25 days at 35oC temperature, 5% pulp5% temperature, 35oC at days 25 in 2 pH at 2 percentage was observed. The maximum value maximum The observed. was percentage by bioleaching of sea nodules under the above the under nodules sea of bioleaching by Aspergillus niger 111 Bacillus circulans tent. During application of water Water mist system in operation to gs gs indicate maximum cessation 96%, 79% and 50% with pyrite ty of explosion.of ty K with both the additives. The hoails ferroxidans Thiobacillus mist and hereby confirm the confirm hereby and mist he he metals followed diffusion- gal bioleaching is an indirectan is bioleaching gal . . The recovery of Cu, Ni and sea nodules. These nodules These nodules. sea etals by acid wash of fungal mtl crooae the corroborated metals f Ni, 86% Co, 91% Mn andMn 91% Co, 86% Ni, is is well below the explosive control open fires n n 1% e were Fe 17% and Mn is a direct enzyme TO and
S&T Contributions CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 S&T Contributions WEIGHING MACHINES 700-900 hexagona to cubic from transition phase undergo and It thehas amorphous thabeen cage. observed silica to temperatures different at annealing by followed can act as capping agent as well. The samples were of load cells. load of deviation of lowering and repeatability increase in a major The requirement. upon the depending thereof randoml or sequentially loaded be can cell load the thus reducing pn the stabilization os time using and and precise vibration co minimizes mechanism individually The cylinders. weights dead the novel of a uses unloading machine The panel. front the on switch and manual mode via a menu Window-based driven Soft can It measurement. of range the throughout ppm ±50 of capacity a has machine Calibrator.The cell Load automati fully a fabricated and developed designed, load of standardization of requirement the meet To aohshr eeoe i aot m Te rwh pa insi growth studied systematically also The were nanophosphors nm. 4 about is developed nanophosphor thickn studied and the capping optimum ZnO thickness ZnO is determined with properties nanop ZnS:Mn photoluminescent of synt surface the for on layer capping method ZnO of simple and unique nanoparticles a capped in-situ by ZnO. Characterizati devised has NPL ZnS:M amorphous the cr to ordered an heating by amorphoussolid produce to structure bcc thermodynamically. open The phenomenon of inverse meltin relatively the wh phase amorphous the to transforms that structure h close-packed the is it that states which melting, pr has NML structure. open totally a and tra structure structure packed loosely a where reaction phase transforms structure to the w this and to When an amorphous phase, quenching. simu on temperature room In the Ti-C system, it is possible to retain the bo Ti-Cr SYSTEM THE IN MELTING INVERSE LOAD CELL CALIBRATOR FOR THE LOAD CELL USED IN USED DIGI CELL CELL CALIBRATOR THE FOR LOAD LOAD n NANOPARTICLESn o C. This is one of the first reports on hexagonal Zn 112 dy dy centered cubic (bcc). structure at ntrol of Load–Time cycle. Further prepared using sol-gel technique exagonal closed packing (hcp). packing closed exagonal the of efficiency the calibration t nanocrystals thesizein grow on studies show the formation 500 Kg and an uncertainty of uncertainty an and Kg 500 ltaneously. This is an unusual remove trapped fluid inside fluid trapped remove y in steps of 20 kg multiple kg 20 of steps in y indigenouslyhas NPL cells, c dead weight machine –the machine weight dead c de a SiOa de sne mdlo inverseof model a esented ystal structure. ystal . . Particle size of the ZnS:Mn of transformation the ereas g also offers the opportunity dvantages achieved are the are achieved dvantages som t a close-packed a to nsforms l at temperatures between temperatures at l ehd o laig and loading for method be operated both in auto in both operated be S formation in nanophase. ilto o ed weights dead of cillation ware ware or through a toggle s neld t 7 K it K, 873 at annealed is rils Te hne in change The articles. s vrain a been has variation ess uaial operating eumatically aees o ZnS:Mn for rameters hs i forbidden is phase 2 eiig ZnS:Mn hesizing gel matrix, which matrix, gel TAL inside inside is gasses with filled like N sizes 500mm. below The shell is composed of silica ceram hollow nonmetallic and inert lightweight, are a fly of quantity large a combustion coal by energy and content ash high contain coals Indian ash. fly re the for process novel a developed has RRL-Bhopal ASH FLY FROM CENOSPHERES OF RECOVERY unburnt carbon below 1.5%, broken particles (sinker particles broken 1.5%, unburnt carbon below processed Cenospheres are characterized to have bul have to characterized are Cenospheres processed pr fl of grades different offrom cenospheres recovery A quality. product maximum achieve to integrated oil, refractory etc. The cenospheres have been sele r include applications of areas The filler. mineral engineeri several in material filler as application sound, electricity and heat. By virtue of the abov characteristics flowing free excellent and strength Photo Photo Micrograph of Cenosphere concentra 1 2 Load Load cell Calibrator or CO 113 2 . . The cenospheres have high compressive e e properties they find widespread ctively separated and judiciously ubber, plastics, polymers, paint, polymers, plastics, ubber, ng materials as replacement to replacement as materials ng . These are good insulators for insulators good are These . y ash has been developed. The developed. been has y ash and and alumina and hollow space during generation of thermal of generation during sh is generated. Cenospheres generated. is sh ic spheres found in fly ash inash fly in found spheres ic s in water) below 2%. s below water) in k density around 400kg/m around density k covery of cenospheres fromcenospheres of covery cs fo set o the for sheet flow ocess 3 ,
S&T Contributions CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 S&T Contributions the component in various sugar mills in the country the in mills sugar various in componentthe la the of view in savings substantial monetary a to conventional (imported ones) ones with improved per improved with ones ones) (imported conventional around by cheaper be componentsdeveloped would The in analysis hammer tips performing are 1.2 times better trial than th Field evaluation. performance for different compositions are under field trial in a s technology with mild steel substrate. The hammer t mater developed the using fabricated has RRL-Bhopal mi sugar the all by tips hammer of Lakh 1.50 around c sugar the fibrizing for used mill sugar a of unit essentia most the are imported, mostly tips, Hammer MILLS SUGAR FOR TIPS HAMMER FIBRIZER EFFECTIVE COST panels. sandwich of preparation for suitable sheet casting continuous through scale larger relatively sy to made being are Attempts 2-4J/cc. from varying the with foams available commercially theto comparable of properties mechanical The absorption. energy thickening and foaming agent. These foam materials through (0.1-0.5) density relative varying of foam RRL-Bhopal has synthesized aluminum alloy foam and PORE CLOSED ALUMINUM FOAM Sugar mill along with fibrizer fitted with the hamm 114 er tips developed at RRL, Bhopal under field trials ugar ugar mill for the last three months rge volumes of consumption volumes of of rge ane. There is a requirement of requirement a is There ane. ip ip component (60 Nos.) of two liquid metallurgy route usingroute metallurgy liquid e e conventional imported ones. technique for obtaining foam obtaining for technique . are are very useful for shock and lls in the country every year.the every country in lls iae ta te developed the that dicated nthesize aluminum foam in foam aluminum nthesize energy absorption capacity absorption energy l components of a fibrizer a of components l ials and joined by brazing by joined and ials R- lmnm om is foam aluminum RRL- aluminum aluminum –SiC composite formance 50% as compared thetocompared as50%
thereby leading thereby 2004. Fifty class XI students in participated CPYLS progr RRL- THIRUVANATHAPURAM the programme. CSIR including institutes R&D tota industries, A different Delhi. New NPL at 2005 10-14, January during “User awareness programme on material characterizat NPL Human Resource Development 1.13.3 98% purity. rec were sterols free the of 85% process this By g. bench scale studies theg) process (500-100 was suc for and supplements food for ‘E’ vitamin natural as 1.13.4 Recognition Recognition & Awards 1.13.4 scale. Residual phytosterols are also recovered at at recovered also are 60% > with Concentrate 90%. to recovery phytosterol phytosterols Residual scale. An Integrated process with phytosterols was develop VEGETABLE OF DISTILLATE DEODORIZER FROM PHYTOSTERDS cec,frcnrbto ntefedo NEERI Metals Heavy of Dr. D.M. Dharm Retrieval and Chemistry Environmental of the field contribution in for Science, of Academy Maharastra Fellow, Elected Bijuranjan Dr. Sciences Planetary Ocean and Atmosphere, of Earth, the field D. Dr. Basu, CGC CSIR Young of 2004 in Scientist Award Indiaof Society Research Materials by 2004 given Medal MRSI- D. and Basu Drs. M.K. CGCRI 2005 hydroxyapatite- calcium synthetic from implants orbital prorous of production the for Process – Invention NRDC for Technology the Award 115 amme held on 27-28 December, with distillate the from overed cessfully tested at cessfully scale pilot 25 labs & universities attended universities & labs ed ed RRL-Trivandrum at hench ion techniques” was arranged has good commercial value commercial good has pharmaceuticals. After the After pharmaceuticals. hs tp ehnig the enhancing step, this l of 45 participants from participants 45 of l Nayak, NML adhikari, RI Sinha, OIL
S&T Contributions CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 S&T Contributions equipment for the year 2004 A. Manda, K. A. and S. Bas, Bhopal RRL- Jorhat, S. C. Bh Dutta K. D. Ms 2004 year the for equipment Bhopal RRL, and RRl- plant Barnwal, Dr. J.P. process of development or in design excellence for NOCIL Award RR S.Das, Dr. 2003 Metallurgist’s Award Day National CoalIIME award beneficiation Dr. N. Ramakris Engineering of Academy National of Indian Fellow S.M. Dr. Shivap ISO.9001:2004 Dr. Haranath, NPL Scientist NPL of the2004 Year Award Dr. Arvind Sinha, NML Dr. Haranath, NPL of 2004 Scientist YoungAward NPL Young 2004 of CSIR Scientist Award Dr. S. Srikanth, the MRSI2005 year for Medal Institute Indian thefor of 2004. year Metals of of Year the Award Metallurgists for thefor RRL-Thiruvanathap 2004year spices” dry and fresh from compunds active and oleresins oils, essential producing for Technology “Swing the for shield Technology Process CSIR 116 Research Laboratory, Pune Laboratory, Research Materials Energy High L-Bhopal attacharyya, NML of RRL- of rasad, NPL hnan, uram Bhopal o f
CENTRAL MANAGEMENT ACTIVITIES
2.0 PREAMBLE
CSIR has, under its umbrella, a network of 38 laboratories and 39 field/extension centers, which are multi-disciplinary and multi-locational, manned by around 17,600 committed staff. The R&D activities and affairs of CSIR are managed by the Director General with the assistance of a multifunctional and multi divisional CSIR Hqrs. under the guidance and direction of the Governing Body (GB) and the Advisory Board (AB). The policy directions are outlined by CSIR Society, which has Hon’ble Prime Minister as the President and Minister of State for Science & Technology & Ocean Development (IC) as Vice President. The Central Management Activities CSIR Annual Report 2004-05 during the year are outlined here:
2.1 CSIR SOCIETY
The meeting of the CSIR Society was held on 26 th July 2004 at 7, Race Course Road, New Delhi. The following items were adopted by the Society:
• Confirmation of the Proceedings of the Meeting of CSIR Society held on 10 th April, 2004;
• Consideration and adoption of the Annual Accounts of CSIR for the year 2002- 2003; the audit report and CSIR’s comments thereon;
• Adoption of CSIR Annual Report 2002-2003. Activities
119 Central Management CSIR Annual Report 2004-05 Central Management Activities journey of the CSIR.of journey Singh, Singh, Hon’ble Finance Minister and the members of a warm welcome to the Hon’ble Prime Minister and Pr Science & Technology and Ocean Development and Vice At the outset, Shri o Minister Hon’ble Kapil Sibal, under: as are meeting the of proceedings The Sibal as its Vice-President.its as Sibal forward-loo a have to privileged was CSIR that said as the President of the CSIR Society, he (PM) would CSIRto was receive his valuable privileged guidanc Finan then the of capacity in earlier CSIR the with the meeting. He said that the Hon’ble Prime Minist CSIR Society as thanked its and President for him s the Aviation by the maiden flight of thatSARAS flight too the by the maiden Aviation months. Excerpts of his address are: address of his Excerpts months. in Program Minimum Common the through vision new a This This makes me feel optimistic about the future of C Kelkar Committee Report.Committee Kelkar mentione he CSIR of zeal real the tap To potential. CSthat opinion the of was he time same the As man. need of wide publicity of these path-breaking devel i indelible technique, printing finger DNA Malaria, f baby Amul tractor, Sonalika and Swaraj mentioning notice the commitment and passion with which member general appreciation of CSIR from business communit business CSIRfrom of appreciation general the way for protecting traditional knowledge streng today was nation’s strongest sa holder of intellectual business and patent and conscious quality become projects laboratories, its of management in changes He statusthe 2003-04. in with it comparing and 96 He thanked Hon’ble Prime Minister for setting up ne Shri Sibal then invited Dr. Mashelkar to make his his p make toMashelkar Dr. invited then Sibal Shri Dr. Mashelkar Dr. made a presentation detailed tracing Dr. Mashelkar Dr. welcomed the Prime Hon’ble Minister t He said, “ said, He He congratulated the 'TEAM SARAS'opening for a congratulated new He e plue laesi o CI fris mat n t on impact its for CSIR of leadership applauded He I am proud and fortunate to be the Vice-President o Vice-President the be to fortunate and proud am I 120 SIR”. s of the family view their responsibilities. property rights and was leading f f State Charge) for(Independent er had been intimately connected d about the implementation of implementation the about d paring his time paring toover preside said that CSIR has brought seaCSIRthat brought has said ce Minister. Even at that timethat at Even Minister. ce opments amongst the common th. th. He briefly mentioned about CSIR’sguide destiny. He also e. e. He confident was that now k place on 29 k place nk etc. He stressed upon theupon stressed He etc. nk esident, CSIR, Dr. Manmohan the CSIR Society to the AGM. IR was yet to achieve its realits achieve toyet was IR n porme ad has and programmes and king leader like Shri Kapil Shri like leader king y by placing it on the samethe on it placing by y resentation onresentation ongoing the w paradigms - giving India back back CSIR's status in 1995- v. e de ta CSlR that added He vvy. President, CSIR extended o, -A fr cerebral for E-MAL ood, o o his first meeting of the e oit particularly society he chapter in the field of chapter field thein the short span of twoof span short the f CSIR. I am happy tohappy am I CSIR. f th May, 2004.May, platform shared by corporate stalwarts like Infosys, Wipro, Hindustan Lever, Reliance, and Ranbaxy etc. He also referred to the book by Dr. Jayant Narlikar "The Scientific Edge" which graded CSIR amongst the top ten achievements of 20 th Century.
He categorized the activities and accomplishments of CSIR in four broad categories namely (i) private goods and services (ii) public goods and services (iii) strategic goods, services and technology options and (iv) social goods and services.
Concluding his presentation, Dr. Mashelkar expressed his gratitude to the members of CSIR Society for their time and hoped that CSIR would benefit from their wise counsel in its future endeavours.
The Prime Minister assured the Society of his keen interest in the development of science & technology and scientific and industrial research in India. He said that he would like to reassure that these areas would remain subjects of high priority for him and the government.
The Prime Minister sought advice and support with respect to policies and programmes in the area of science and technology. He congratulated CSIR for the remarkable transformation into a performance driven and user focused organization.
The Prime Minister stated that he felt proud by the successful maiden flight of
SARAS and was sure that it would herald the dawn of civil aviation industry in CSIR Annual Report 2004-05 India and would become a ‘brand name’ for small aircrafts world over. He dwelt upon the decisive role of S&T system for the well being of all sections of society not just a privileged few; “ A theme that is close to my heart is on ‘making technologies work for the poor and the underprivileged’.” He stressed on the need to develop technologies, which would ameliorate the poverty, create jobs, remove the disease burden of the poor, and improve the overall quality of life. He was sure that CSIR could address the special issue of the disease burden of the poor by developing life saving drugs at reasonable prices and not only drugs, but also the areas like water, housing for the poor, fireproof structure etc. where CSIR can contribute a lot.
The Prime Minister advocated an approach to rural development by applications of science to break new grounds in increasing productive capacity of small farms and small businesses by implementing employment intensive schemes. He pointed out the importance of having decentralized power in terms of local electricity generation, where CSIR could be of much help.
[The full text of the speeches made by the Hon’ble Prime Minister and President- CSIR Society and Hon’ble Minister of Science & Technology, and Ocean Development and Vice President, CSIR Society are given in Annexure VII.] Activities
121 Central Management CSIR Annual Report 2004-05 Central Management Activities modification of scheme for grant of temporary statu of temporary of grant for scheme modification introduction PSUs; bodies/ autonomous the to scheme supportand st technical scientific, of recruitment CSIR to amendment 2001; rules, promotion assessment CSIR to amendment more; or year one of period a for instructions to relating of abolition deemed posts S&T strength of CSIR and exemption formulatio from implementat proposals; Schem Award performance outstanding and suggestions NMITLI originated industry of of outreach center setup by CSIR; modification in e Medal for excellence in science”; report of the Com Innovation Institution Foundation (NIF); of an Awar The Governing Body of CSIR met two times during the during times two met CSIR of Body Governing The (GB) BODY GOVERNING 2.2 and 15 and ratification. o GCI t gat eeto o le byn to ye two beyond lien thein of equipment R&D upgradation and facilities of retention grant to DG,CSIR to between CSIR and other organizations of autonomous Service Rules, 1994 for recruitment of Technical an (SARAS) and associated building at NWTC by NAL,Bang CSIR Administrative Services Rules-1982; proposal f Swarup Bhatnagar Prizes-2004; CSIR Young Scientist Technology Awards-2004; CSIR Diamond Jubilee Techno re the with consultant appointed the of affiliation l development; national business of for consultants Heads of to engagement powers of devolution abroad- supporte projects the utilization of loan to repayment for schemeNMITLI pro period intermittent the in NMITLI project scheduled for completion; provision to industry under NMITLI scheme- policy directive f subjects and gave directions on these issues.these on directions gave and subjects On 15 n 26On th December 2004. The GB in its meetings deliberated meetings its in GB The 2004. December th th December, 2004 in its 163 July, 2004 in its 162its in 2004 July, nd meeting, the GB approved: creation of Nationalof creation approved: GB the meeting, rd meeting, the GB approved: financial support 122 aff; applicability of new pension new of applicability aff; mittee to review the performance kept in kept in abeyance or lying vacant xisting procedure for processing d d Support Staff; mobility of staff or construction of aircraft hangar spective CSIR laboratory; CSIR laboratory; CSIR spective of providing financial support s. 9 or sanctioning loan; review of d Ramachandran d “G.N. Gold Awards-2004; Awards-2004; amendment to jects; jects; deputation of scientists th udr MTI scheme; NMITLI under d nature-delegation of nature-delegation power Five Year Plan-review and Year Five Plan-review Scientists recruitment and recruitment Scientists ion ion of GOI, Min. of Finance rvso fr temporary for provision year i.e. on 26on i.e. year alore; amendment to CSIR of new pension scheme; pension new of logy logy Award-2004; Shanti r; oenzto and modernization ars; b.ist; cee for scheme abs./instts; evc rls 94 for 1994 rules service e 2004; re-fixing of core of re-fixing 2004; e o CI innovative CSIR of n on several crucial several on th July 2004 July 2.3 ADVISORY BOARD (AB)
The Advisory Board (AB) is an apex body of CSIR to provide S&T inputs to Governing Body, advise CSIR in implementing its vision, review major R&D areas of CSIR and suggest new R&D perspectives, network/ mission oriented programmes and their priorities. The Board discussed the performance appraisal of all the laboratories carried out by Performance Appraisal Boards (PABs) comprising knowledgeable and experienced experts from industry, government, research and academia. The reports of PABs were submitted to a High Level Committee (HLC) chaired by Prof. M.M. Sharma. The HLC recommended that laboratory wise performance appraisal be divided into two parts (i) confidential and (ii) non-confidential. The non-confidential part and the overarching executive summary are to be processed by AB. The eighteen actionable points vis-à-vis recommendations of HLC were presented before the AB.
The report of the Kelkar Committee was presented to Advisory Board. The Committee had studied various methods employed for assessment and evaluation of publicly funded R&D organizations abroad and decided upon social Benefits Cost Analysis (BCA) as a general framework for the study of CSIR. Selected six representative CSIR laboratories NAL, NCL, NPL, CCMB, CFTRI and RRL Jorhat for the study. The Kelkar Committee inter-alia recommended that CSIR must realize autonomous society status; revisit the R&D managerial processes; initiate CSIR
Jewels Scheme; optimize outcomes through relationship management, enhance CSIR Annual Report 2004-05 human centered resources and create incentives for the growth.
The AB considered recommendation of the High Level committee of PAB and the Kelkar Committee. The AB appreciated CSIR openness and transparency in bringing the system for periodic appraisal. It suggested that Research Council (RC) of the laboratories should be mandated appropriately and expeditiously to implement these recommendations. AB also suggested that CSIR should ensure that new areas of Science & Technology were given higher priority.
2.4 DEPARTMENT RELATED PARLIAMENTARY COMMITTEE
The Department Related Parliamentary Committee on Science & Technology, Environment and Forests examines and recommends the demands of grants of the DSIR including CSIR. It also takes up specific topics/ subjects of national S&T interest for deliberation from time to time. The Committee considered the Demand of grants for the year 2004-05. A background note was prepared highlighting Activities
123 Central Management CSIR Annual Report 2004-05 Central Management Activities . SR ONAIN DAY FOUNDATION CSIR 2.5 • • • • • • • • • suggestions: observations/ activities, programmes and financial summary. The C Ocean Development. Ocean Min Hon’ble Sibal Kapil Shri by graced was function The Chief Guest was Dr. Ashok Ganguly, Chairman, IC du service of years 25 completed have thosewho and family CSIR the of contributions the excellence acknowledging recognizing for day a also is It future. th of progress Foun the of the stock take as to – day introspection this celebrate labs CSIR 38 the All 1 in day this on was It (CSIR). Research Industrial for day important very a is September Twenty-sixth better better which products, eventually reach would the e lab research among promoted be co-ordination closer knowledge; traditional our to rights indisputable futur in vigilant remain and filings patent Foreign number achieve to institute pioneering a as emerge uptheir setting for scholars research theto loans an agreement should be reached with various financi R and industry between interface a there greater is disseminatio wider for need a also and technologies industry from funds raise to made be should efforts as large parts of our country live in villages; in live country our of parts large as develop technologies to use locally available mater pollution; environmental cause otherwise develop fuels from waste matter and other non bio-d living the improving for revolution silent a usher A allergic on focused be to needs attention special publicity of the medicine already discovered by the polluti prevent & curb to standards quality ambient review and monitor to tools scientific new develop CSIR Headquarters organized the main function this this main thefunction organized CSIRHeadquarters 124 e past years – and plan for the for plan and – years past e 942 that CSIR was established. was CSIR that 942 hog vros wrs and awards various through own enterprises; own ommittee has made following ial ial for construction of house, conditions in rural areas; rural in conditions ring the past year.past the ring ain a. t s dy for day a is It Day. dation CSIR is grossly inadequate, sthmas; members who have retiredhave who members &D laboratories;&D ister of State (IC) S&T and S&T (IC) State of ister egradable substances which ICI One Source Ltd. and the the Council of Scientific & Scientific of Council the e to safeguard our age old age our safeguard to e al al institutions for providing nd nd users of such products; on in the country;the in on the existing health based health existing the by successful transfer of transfer successful by one position in Indian & Indian in position one n of technologies so thatso technologies of n year in NPL auditorium. NPL in year oratories for producing for oratories In his Welcome Address, Dr. R. A. Mashelkar, Director General, CSIR announced that CSIR’s birthday was being celebrated across all the 38 laboratories of CSIR. He said that Shri Sibal, since taking over the reins as Minister and as Vice President, CSIR has “both charmed and charged” the entire CSIR family by his ‘dynamism, his vision, his optimism and his penchant for action.’ He expressed the hope that, as CSIR tries to forge ahead, it would be Shri Sibal’s momentum and drive that would “take us to our destiny”.
He highlighted some of the exciting things that have been happening during the last three or four months. He chose to focus on four events that according to him symbolized the fact that Indian S&T was taking a new turn. He elaborated each of these four especially chosen “exciting things” and underlined the symbolism behind his choice; the four exciting things’ were:
• SARAS: maiden flight on 22 nd August, 2004, which signified “Sanctions cannot be put on our minds.”
• The launch of BioSuite® – an unique software that was developed with Public- Private Partnership (PPP) with Tata Consultancy Services (TCS) and 18 other institutions – many of them from CSIR – at San Francisco, USA. It showed “What we cannot do alone we can do together.”
• The breakthrough in tuberculosis, which affects people around the world. Five lakh people die of it in our country annually. The breakthrough came in the
form of a new molecule – the first to be discovered after 1963. CSIR Annual Report 2004-05
• Completion of the Phase 1 clinical trials for the treatment of psoriasis.
Shri Kapil Sibal, Hon’ble Minister of State (Independence charge) for S&T and Ocean Development presented the CSIR Young Scientist and CSIR Technology Awards for the year 2004. The winners of Shanti Swarup Bhatnagar Prizes for 2004 were also announced. The Minister in his address to the gathering mentioned of the importance of an institution’s maturity in S&T for the development of the country. He appreciated the way indigenous R&D has responded to the challenges in the form of inaugural flight of SARAS; manufacture and export of Indica and Indigo cars to the western world and many more. He highlighted the currently small but potentially large electronics industry and the achievements of the thriving software industry. The Hon’ble Minister stressed upon today’s need of Public- Private Partnerships. He stated that he was extremely delighted to note the four noticeable recent achievements in Indian science, three were the results of Public- Private Partnerships (PPP) under NMITLI.
Shri Sibal also stressed upon the need for education, not just primary education, which of course, should be available to all children in India, but for quality higher education. He stated that with the removal of quota restriction under the WTO, Activities
125 Central Management CSIR Annual Report 2004-05 Central Management Activities . HNI WRP HTAA PIE 2003: PRIZES BHATNAGAR SWARUP SHANTI 2.6 theto important etc. electronics industries, based hydrocarbo as such significance of areas other were was going to a be fifty million industry dollar in sector coul which sector, service the was sector vital important a into grown has industry textile the Minister ManmohanMinister Dr. Singh at a functio glittering presen were 2003 for Prizes Bhatnagar Swarup Shanti Science and Technology have to offer. It is a very very a separatel is held be to used events It science previously offer. to have Technology and Science the of celebration of evening evening—an great a is innovation is innovation the key word.” iitr f tt (needn cag) cec & Te & scientists. distinguished and dignitaries Science charge) att was It CSIR. of President Vice and Development (independent State of Minister b over presided was function The Bhavan. Vigyan at said. t that affect uncompleted somethe tasks of address t needed CSIR now itself reinventing of process the glob the of challenges the meet to reforms economic compan international and Indian with partnership in labora CSIR most that redefined/ their remodelled stated role in order to enhanc He capacities. associ long various his recalled He RENEWAL’. OF CHALLENGE think of another dream we want to fulfill, step to h CI Tcnlg Aad (04. inr f h CS also 2004 were Schoolfor Invention Awards Children the of Winner an Prizes Bhatnagar Swarup Shanti Award, (2004). Technology Awards Technology CSIR the CSIRS Youngaway the gave also He Mashelkar. A. R.
Welcoming the invitees, Dr. R. A. Mashelkar, Direct Later, Later, Shri Kapil Sibal released a book entitled Chief Guest Dr. Ganguly delivered the foundation da foundation the delivered Ganguly Dr. Guest Chief Dr. Vikram Kumar, Director, NPL proposed a vote a proposed of NPL Director, Kumar, Vikram Dr. In summation, Shri Sibal reiterated, RSNAIN CEREMONY PRESENTATION His His message parting to the young scientists was “Technology is the way ahead and in technology 126 step, step, hand in hand.” the the times to come. thereSimilarly growth of Indian economies. Indian of growth Vaigyanik Vaigyanik Bharat ka Nirman e e their wealth creating abilities he vast majority of Indians, he of Indians, he majority vast d generate a lot of money andmoney of lot a generate d y and technology events usedevents technology and y f nin cnm. Another economy. Indian of n onheld 13 ns and biofuel industry, agro industry, biofuel and ns al marketplace. However, in However, marketplace. al ended by a large number of number large a by ended announced. ey et ht oh Indian both that best very ies and in tune with India’s with tune in and ies rs t te hleg and challenge the to rise o nqe vn a normally, as event unique or or General, CSIR said, “This y Shri Kapil Sibal, Hon’ble Sibal, Kapil Shri y cientist Awards (2004) and (2004) Awards cientist ted by the Hon’ble Prime Hon’ble the by ted d CSIR Diamond Jubilee Diamond CSIR d ois a successfully had tories thanks. y lecture on `CSIR-THEon lecture y hooy n Ocean and chnology R imn Jubilee Diamond IR to wt SR in CSIR with ation th September 2004 , , “Let us by Dr to be held separately. He believed that it was the first event when the best of Indian Science and the best of Indian Technology were being applauded together.”
He spoke glowingly of the indigenously designed and built Saras’ soaring “flight into the future” and the breakthrough in psoriasis (“a very difficult disease”) and tuberculosis (“the first new molecule on the horizon since 1963”). He spoke of development of the unique partnership with Tata Consultancy Services and the development of Bioinformatics software Bio Suite (“software first launched in San Francisco, then in Hyderabad”).
In his address, Shri Kapil Sibal said that it was an “intermingling of high science with technological innovation and daring entrepreneurship that was necessary to propel India to a developed nation status”. He said that the marriage of high science and high technology in a sense symbolizes the underlying spirit of CSIR, that is, to strive for excellence in science and to apply it to uncharted technology domains.
Dr. Manmohan Singh Hon’ble Prime Minister, gave away the first Diamond Jubilee Technology Award for 2003, instituted last year in commemoration of the CSIR Annual Report 2004-05
Hon’ble Prime Minister presenting 1 st Diamond Jubilee Technology Award to Shri Ratan Tata
CSIR's diamond jubilee. The award was given to Shri Ratan Tata, Chairman of the Tata Motors, for “setting a major milestone in the Indian auto industry” with the design, development, manufacturing and commercialization of India’s first indigenous passenger cars—Indica and Indigo. The award consists of a cash prize of Rs. 10 lakhs and a shield, conceptualised and designed in association with the National Institute of Design, Ahmedabad. It is given to a technology that is developed in the country by Indian innovators and meets the highest global standards. Activities
127 Central Management CSIR Annual Report 2004-05 Central Management Activities need for reconstruction of the university system an system university the of reconstruction for need far, far far, more than it has done.” opportunity, of kind this given and scientists such th in shot tremendous a is recognition of kind This a chance to prove themselves. We need to recognise capabilitie tremendous talent in young scientists and (own) young eng our in believe to need Indians as skill and the human capital, but we sometimes lack Science and Technology arena in India today. We hav achievements such many many, and projects such many coun his of proud is who Indian “an As fruition. to despite said teething He troubles and done.” frustrations be and fina couldn’t said many that challenge youn 700 the of behalf on it receive to honoured am Aw this receive honourto great extremely an is “It considered for thefor award.considered a sustaina processes which India give services, and to to prestige the coTechnologies leading nation. inno technological outstanding most the acknowledge science an attractive career for our young people,” young our for career attractive an science re must “We students. many for choice automatic the undergrad and attention,” said the concer He PM. was particularly 10+2 at education science particular, to be developed to induct, nurture and retain young piecemeal fashion and had to be taken up comprehens base in pointed He theout universities. that this In his address, Hon’ble Prime Minister Dr. Manmohan Dr. Minister Prime Hon’ble address, his In In In his acceptance speech, Shri Ratan Tata, Chairman h ana CI Daod uie Tcnlg Aad wa Award Technology Jubilee Diamond CSIR annual The Hon’ble Prime Minister addressing the audience 128 rebuilding could not be done rebuilding ain lly lly the Indica project was brought mmercially successful products,mmercially their abilities and achievements. he said. he the belief that we can do it. We, ard on behalf of Tata Motors. IMotors. Tata of behalf on ard ble competitive advantage, arecompetitive advantage, ble I think this country can shinecan country this think I ned thatned science was no longer d rebuilding of the science the of rebuilding d try”, he felt, “There are many, are “There felt, he try”, talent in the science stream. In e arm for such engineers and engineers such for arm e the accepted who engineers g ineers. We ineers. need to give them is “There continued He s.” e the manpower, we have the ively. “New “New strategies ively. need double our efforts to maketo efforts our double , , Tata Motors Limited said, ht h ta persevered team the that ae ees ed special needs levels uate ain ht a brought has that vation that are possible in the in possible are that Singh emphasised the emphasised Singh isiue to instituted s Dr. Singh on the occasion announced that he would soon constitute a Science Advisory Council to the Prime Minister that would be headed by a distinguished scientist. The mandate of the Council would be to provide advice on strategies, policies and programmes for using S&T as an essential input for all developmental processes.
Shanti Swarup Bhatnagar Prizes-2003-2004 Later, Dr. Manmohan Singh gave away the Shanti Swarup Bhatnagar Prizes for the year 2003. The Shanti Swarup Bhatnagar Prizes are awarded every year by CSIR to outstanding Indian research workers in seven disciplines of science and technology. The Prizes are awarded to scientists for their outstanding scientific CSIR Annual Report 2004-05 contributions made primarily in India during the last 5 years preceding the year of the award. The Prize comprises a citation, a plaque and a cash award of Rupees two lakh. This year 13 scientists were given this award.
Earlier, referring to the Awards Dr. Mashelkar had stated, “There is no question that the Shanti Swarup Bhatnagar Prize is the most prestigious award that India has to offer. One can get many awards and international honours in one’s life time but as a scientist, it is the most cherished award.”
Prof. Samir K. Brahmachari, Director, IGIB proposed a vote of thanks and expressed gratitude to all those who made the occasion a grand success.
2.7 SHANTI SWARUP BHATNAGAR PRIZES 2004
CSIR formally announced the winners of Shanti Swarup Bhatnagar Prizes, for the year 2004 the country’s highest award in science, as a part of the CSIR Foundation Day Celebration organized at the National Physical Laboratory, New Delhi. The Hon’ble Minister of State (Independent Charge) Science & Technology and Ocean Activities
129 Central Management CSIR Annual Report 2004-05 Central Management Activities Mathematical Sciences: Chemi National Ranade, Vinayak Vivek Dr. and Bombay Sciences. Atmo Earth, of field the in given been has Award no Medical Sciences: Res Fundamental of Institute Tata Ramdorai, Sujatha Sciences: Engineering and Siva Dr. Umapathy, Indian Institute of Science, Physical Physical Sciences: Delhi. New and Biotechnology, gineering University statusUniversity Web and ISTAD E funds; of Release recruitment); Valor ‘B’ Scientist for I.P. o (Introduction including issues HRD and Training Assessment, Development Business Projects; cussed were: cussed Bangalo NAL, at 2004 21-22, August in organized was interest. A cuss two da generic ofissues/ problems CSI of forum annual an is Conference Directors’ The CONFERENCE DIRECTORS’ 2.8 Biological Sciences: Bhatnagar year’s are:Prize fu the over presided Sibal, Kapil Shri Development, Chemical Sciences: Chemical Pune and Dr. Ramesh V. Sonti, Centre for Cellular & ekr omte Rpr’ rcmedtos Guidelin recommendations; Report’s Committee Kelkar Dr. Chetan Eknath Chitnis, International Centre fo Dr. Dr. Madan Rao, Raman Research Institute, Bangalore. Dr. Vinod K Singh, Indian Institute of Technology, of Institute Indian Singh, K Vinod Dr. Dr. Dr. Gopal Chandra Kundu, National Centre for Cell S Dr. Subhasis Chaudhuri, Indian Institute of Techno of Institute Indian Chaudhuri, Subhasis Dr. Dr. Arup Bose, Indian Statistical Institute, Kolka 130 -Governance in CSIR, Deemed CSIR, in -Governance Molecular Biology, Hyderabad. y conference of CSIR y conference Directors Bangalore. sphere, Ocean and Planetary and Ocean sphere, R Directors to meet and dis- and meet to Directors R earch, Mumbai. earch, nction. The winners of this of winners The nction. f centralized examination centralized f re. The major issues dis- issues major The re. cal Laboratory, Pune. Laboratory, cal sto; Recruitment, isation; s o te Network the for es r Genetic En- This year, ta and Dr. Kanpur ciences, logy, CSIR Annual Report 2004-05
The Directors Conference was preceded by Directors sports meet organized as a part of Silver Jubilee function of CSIR Sports Promotion Board.
Directors’ sports meet Activities
131 Central Management CSIR Annual Report 2004-05 Central Management Activities 132
out by the divisions during the year are summarized are th year the during divisions the by out out carried are These administrative divisions set up for the matters. purpose. So related vigilance c and linkages development; extramural human resource development; international to gateway property; Commission; intellectual managing guidelines; policy n lbrtre. t lo a te epniiiy t InvestmentCommittee GB. Sub and responsibility the has also It laboratories. and Plann with Ministry, externally and other sector specific co-ordinate departments to and responsibility proposal, proposal, databank of whole CSIR R&D activity, and approval, co-ordination and monitoring of national A Directors’ Performance Conference; (AB); Research Board Council (RC) and Advisory ma etc.; Commission Five Year Plan and related matters; Annual Demand Reportdepartments; Government ( with interaction as R&D Planning Division is the nerve center of CSIR H (RDPD) DIVISION PLANNING R&D 3.1 T ih eeec t te ewr ad iia projects, similar and network the to reference With he CSIR Headquarters is the central hub of its 38 l 38 its of hub central the is Headquarters CSIR he ciiis nld srtgc lnig rpstr o repository planning; strategic include activities EDURES ACTIVITIES ACTIVITIES HEADQUARTERS HEADQUARTERS EDURES ACTIVITIES ACTIVITIES HEADQUARTERS HEADQUARTERS 135 me of the major activities carried AR); Report to Cabinet, Planning internally with Finance Division poie ehia spot to support technical provide o laboratories, S&T plan projects/ tters pertaining to formulation, qrs. qrs. with broad activities such execution of New Idea Fund. below. rn fc t te Planning the to face front n Cmiso, Finance Commission, ing ognztoa learning; organizational f og te ehia and technical the rough aboratories, whose primewhose aboratories, solving legal matters and for grants; Annual Plan; Annual grants; for laoain; business ollaborations; pasl or (PAB); Board ppraisal h dvso hs the has division the
Hqrs Activities CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Hqrs Activities Flow); and Flow); receipts. internal The TFYP was devised techni and consultancies contractR&D, from funding sup budgetary namely: sources, major three the An from TFYP, of corrections term CSIR.for organizat As formulated a funded publicly mid the to sequel a As ANNUAL PLAN 2005-06 Commission. Planning the by principle of funding An Rs.additional 400.00 crore also was by approved got and aspirations and needs economic objectives under CMP has identified prgrammes speci profe institution and building other projects in other the coun and technologists scientists, Indian of global leadership and local transformation; and mob vast S&T infrastructure; development Gove and applicatio the of included three main issues viz. (CMP) introduction of pro the in Technology & Science Programme of role the emphasized Minimum Common National research center; and National nano science and proteomics nano National N species; endangered conservationof of Laboratory facility; toxicology regulatory knock out mice; Augmentation of national trisonic & m and breeding and microorganisms hazardous storing pr facilit training & assurance quality water National projects/ create various be to facilities of the particularly programmes status the and particu achievements Commission Planning (Science) Member before feat salient on presentation A Commission. Planning and prepared was document (MTA) Appraisal Term Mid identi were bottlenecks and shortfalls and analysed laboratories and inputs were accordingly sought. Th proforma seeking information on various issues were these issues. Since the TFYP was based on network p a CSIR undertook measures. appropriate evolving by the possible reasons thereof, and (iii) the mid-ter far, (ii) identification of the areas of significan of areas the of identification (ii) far, three was aim Tenth the of objectives the reaching of The possibility stage. mid-term at economy Indian i the of examination thorough sought has Commission Tenth Y Five of year third was 2004-05 the year The (TFY YEAR FIVE PLAN TENTH THE OF MID APPRAISAL TERM 136 t shortfall in Plan performance and performance Plan in shortfall t m corrections in the implementation Plan, with progress achieved so achieved progress with Plan, try. try. CSIR in consonance with the grammes that strengthen India’s y; BSL-4 facilities for handling, for facilities BSL-4 y; sought was which approved in d were identified. These were These identified. were d n mission in key areas covering aerodynamic facility; National e information so received were ear Plan and such Plan and as Planningear ilization ilization of skills and expertise with with an assumed annual GDP technology programmes. The soas okn ara for abroad working ssionals fied. Based on the analysis, a analysis, the on Based fied. rojects, rojects, a well comprehensive ion, CSIR ion, its financesderives evolved in consultation with ational battery development battery ational ally ally linking these to the socio cal services (External Cash (External services cal made was MTA the of ures developmental process andprocess developmental port from the Government;the from port addressto massive exercise the Planning Commission. Planning the mpact of the TFYP on theon TFYP the of mpact n gnmc facility; genomics and aintenance of transgenicof aintenance ul ln 050 was 2005-06 Plan nual new Also ogrammes. fl- i t ass the assess to (i) -fold- al hglgtn the highlighting larly sent for the perusal of perusal the for sent net had rnment P) asdrn tepeaain fgieie. Te gui The guidelines. of preparation the during labs pro networked of execution smooth to related issues The projects’. Networked of Monitoring de Scientific, for timely `Guidelines prepare achieve to Committee to a and constituted level laboratory at issues croppethese projects haveof networked functioning man project, each in participating are laboratories now in operation. in now of 55 laboratories. CSIR within activities R&D the upon embarked has CSIR Plan, Year Five Tenth the In ON GUIDELINES PROJECTSNETWORK PROJECTS NETWORK CSIR. for approved crore was Rs. 797.53 detailed in depth discussion and later with s Plannin various for crore 935.00 Rs. of investment plan A 2005-06 was formulated and sent for the considerati view in of the priorities through operational plann info informati The sought. also addition, was progress activities/ In requirements. financial vis-à-vis approved by the competent authority were ascertaine planned the against programmes network of progress compreh a through institutes laboratories/ national deta sought division The programmes. priority new investments existing the on building and activities schemeson emphasiscontinuing is The others). with ha period Plan Ninth the of schemes (two scheme new f which of total, in schemes six are there CSIR, of nat the and percent 8 to2 theby percent increasing around of of end GDP of economy the of rate growth on Headquarters for directions and thus increasing increasing deliverables. and thus and directions for expansion Headquarters on project flow, operationalisation of is guidelines expected to red information mechanisms, m pertainin mechanisms, issues co-ordination the aspects, administrative address broadly 2004, October, hs ntokd rjcs r a e eprec fr C for experience new a are projects networked These 137 uce the laboratories dependence ive are continuing and one is a is one and continuing are ive on of the Planning Commission. the ing, Annual Plan document g g Commission, a plan outlay of Committee dwelt upon manyupon dwelt Committee y issues pertaining to smoothto pertaining issues y on was analyzed and keeping and analyzed was on and infrastructure to initiateto infrastructure and ensive proforma, wherein the wherein proforma, ensive these networked projects are projects networked these d along with the future targets In the the TFYPPlan period. chemes was projected. After projected. was chemes d up. In order to In up. order d sortout the delines, operational from 1 from operational delines, mto o non-networked on rmation on consolidation of ongoing of consolidation on jects and involved all CSIR all involved and jects programme of networking of programme iaca, Administrative, Financial, activities as envisaged and envisaged as activities h efcec i trs of terms in efficiency the iled information from the from information iled ieals D-SR has DG-CSIR liverables, ve been closed or mergedor closed been ve ntrn ad evaluation and onitoring t fntoa aspects, functional to g oa RD expenditure R&D ional I. s nme of number a As SIR. oelsr. The foreclosure. st
Hqrs Activities CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Hqrs Activities been screened for different diseases and 3000 sampl 3000 and diseases different for screened been bioeva for sent and synthesized been have molecules hav extracts microbial of number equal and alcohol) pro to them thousand plant extracts (three thousand i. samples, coding after bioevaluation for sent and thousand six of total a programme this In entities. for herbal as development of stages various at are for tuberculosis, stage parkinson’s disease, molecule immunomodulation single to reached have leads the sixty drug discovery groups formed which are are which formed groups discovery drug sixty s a made has project The CSIR. of Project Networked co been has programme The contemplated. be can IND in discovering single molecules from the leads and to m give has been strategy able evolved The arena. re a gets India thereof result a as and made be can mounte was Preparations” Traditional and Bioactives PREPARATION’ COMMERCIALIZATION OF NEW BIOACTIVES AND TRADITIONAL & PROGRAMME ON DEVELOPMENT ‘DISCOVERY, • • • • • • MONITORING COMMITTEE periodic monitoring. The main functions of the Moni the of functions main The monitoring. periodic o objectives the achieve to is Committee Monitoring proj networked the of each for Committee Monitoring assess and advice the mid course changes in network in changes course mid the advice and assess mil and goals agreed of delivery timely the monitor basi yearly half on projects of progress the review each for parameters monitorable and suitable evolve rgam o “icvr, eeomn & Commercialis & Development “Discovery, on Programme projects.of foreclosure and activity, lab of inclusion release, fund additional recommend progress; projec for system warning internal adequate provide n h rcmedtos f DD D-SR a constit has DG-CSIR RDPD, of recommendations the On 138 in vitro in plant extracts have been made been have extracts plant e. in e. aqueous, in alcohol 50%and taking taking them to the stage where any leads for various diseases for leads any cognition in the internationalthe in cognition mulations and new chemical new and mulations es for pesticidal activity. pesticidal for es toring Committee is to: is Committee toring and hepatoprotection. These iess ie le, cancer, ulcer, like diseases e been prepared. 120 single 120 prepared. been e s; teady progress and around and progress teady te rgams through programmes the f luation. 2500 samples have samples 2500 luation. and and et P. uig h year the During IPR. tect d so that new discoveries new that so d estone targets;estone ects. The purpose of the of purpose The ects. nverted into a Task Force Task a into nverted network projects; network ts registering no or slowor no registering ts composition; rtre eein f an of deletion oratories in vivo in active. Someof active. td external uted to o New of ation which enabled formulation of the recommendations.the formulation of enabled which database and provided technical analysis & secretar the from all concern information collected division purposes various for laboratories CSIR the by setup B. B. Dhar to review the performance, relevance and un 2004 March in constituted was committee Review A CENTERS OUTREACH ON COMMITTEE REVIEW CSIR of publicity the scheme was given through New the adver under programme support research `Collaborative f prepared were proforma and Guidelines CSIRlabs. R University, from proposals collaborative inviting suggestions. of the termsin the thereafter achievements Com and scheme. Progress considered of the per three was ongoing host’ projects, heterologous ap a genome-wide in out through carried ORF’s/genes unknown of tion mittee. Only one idea of Chandigarh IMTECH, entitl pr their of presentation for invited were proposals Investigators Project The selected. were proposals Afte received. laborato were NIF CSIR under support for proposals in working scientist the from invited disco a of potential having proposals Fund Idea New NEW IDEA FUND (NIF) Common Program Minimum (NCMP). through applications of technology for rural develo in programs core areas of strength. The would plan Directors’ Conference held at Bangalore during 21-2 during at Bangalore Conference held Directors’ Minister of State Science (I/C), Technology & and O The Rural Action Plan document of CSIR was unveiled ACTIVITIES RELATED ACTION AND RURAL CSIR’S PLAN Presi approved by further been has which committee, The The Governing Body of CSIR has approved the recomme The The Committee also the considered enlarging scope o CSIR has prepared this plan for its own orientation 139 proved earlier was also reviewed pment programs under National ed CSIR laboratories, CSIRprepareded laboratories, oposal before the Expert Com- Expert the before oposal utility of CSIR outreach centers (PIs) of the shortlisted project shortlisted the of (PIs) ial ial assistance to the committee, &D institutions in addition to addition in institutions &D also also CSIRenable to contribute cean Development during the 2 August, August, 2004.2 tisement in `Current Science’. mittee gave its its observations/mittee gave ed ed of`Identification the func- o e upre udr NIF under supported be to over a period of time. The time. of period a over or inviting the proposals onproposals the inviting or towards rural development r rigorous evaluation seven evaluation rigorous r by Shri Kapil Sibal, Hon’ble dent of the CSIRSociety.of dent is Ti ya, seventeen year, This ries. ey rbekhog are breakthrough or very der chairmanship of Prof.of chairmanship der f f ongoing scheme NIF by da ud Te wide The Fund. Idea ndations ndations of the review ubto analysis turbation
Hqrs Activities CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Hqrs Activities CSIR laboratories to large number of people on req on people of number large to laboratories CSIR technolo specific of dissemination facilitated also more to Sector” voluntarily Rural individuals farmers/ NGOs/ departments/ for “Technologies Di The publication technologies. CSIR of dissemination for NGOs Executive Body and General Body of CAPART, so as to Hindi this de and wider muchmore be to With likely is technologies publication. this in place special for the Rural Sector” this year. Technologies relat for publication of four issues of the “Journal of R of “Journal the of issues four of publication for success depicting stories of the CSIRgallery, in t to provided also were Funds CSIR. by supported were laborato two from projects new two and NCL and IICT expeditiously. recommendations formulating in The division also provides technical and secretaria con for projects ongoing the of report progress and inv RDPD funding. for projects suitable recommends r on Committee Monitoring and Advisory have already n eaf f SR h dvso i as poiig it providing also is division the CSIR of behalf On For encouraging development of suitable technologie suitable of development encouraging For Division has also brought out Hindi version of the of version Hindi out brought also has Division This year, nine ongoing projects of four CSIR labor
Hon’ble MOS (S&T) I/Cr unveiling Rural Action Pla 140 ed ed to information have been given he area of rural he development area of andrural ural Technology”. ural gical details through concernedthrough details gical l l assistance to enable committee n document of CSIR uest. sideration of the committee.the of sideration eper among its users.its among eper atories namely CFTRI, IHBT, eso, h rah f CSIR of reach the version, enable funding to deserving ites fresh project proposals project fresh ites RRL-Bhopal for setting of setting for RRL-Bhopal publication “Technologies publication on request. The division The request. on tcncl omns in comments technical s iin itiue CSIR distributed vision ries IICT and NISTADS and IICT ries hn 0 government 500 than rl cinpa, which plan, action ural s for rural sector, CSIR sector, rural for s of Agriculture & Cooperation, Ministry of Agricultu Ministry of Cooperation, & Agriculture of R&D projects and Rs. 112 lakh for ongoing projects of Review Committee. budgetary resources Extra (EB b reportsprogress certificates and o utilization and quarterly on reviewed also was programmes ongoing physical The Committee. Expert by evaluation after were lakh Rs. of222.00 outlay total budgetary with on oilseeds, pulses and maize. Fourteen new R&D pr R & D Planning Division is also designated as nodal MISSION ON TECHNOLOGY & OILSEEDS PULSES (TMOP) CSIR-AIST.sta the obtain to move a initiated has CSIR AIST)”. of Institute “CSIR-Advanced body autonomous an into CSIR proposes to convert its existing entity “Human specialized scientific human resource pool especial Div region. the the for secretariat a as working of of responsibility people the of profiles skill and enable development of technologies, which can blend road map a draw and vision scientific develop would of chairmanship DG-ICAR has constitutedbeen in Dec chairmans the under force task multi-disciplinary A OF NORTH EAST CONTRIBUTION TOWARDS DEVELOPMENT elwhp Cth hm on porme CI Progra CSIR programme, Science in Shanti (CPYLS), BhatnaSwarup Leadership young them Catch Fellowship, Shyama Dr. Award, Interns Research Jubilee Diamond CSIR introduced many programmes for human resource needs T & S and ident D & R to for teachers and aims researchers which (NET) Test Eligibility National conduct is it UGC with association In academia. and CSIR has been contributing to the training of skill CSIR FOR STATUS UNIVERSITY DEEMED pro project revised to forwarded NEC and for labora funding. CSIR detailed with ten of coordinated preparation division the NEC, with r East North the in technologies CSIR disseminating h iiinitrce ihNrh atCucl (NE Council East North with interacted division The elsn ta i hs h cpct t cet a larg a create to capacity the has it that Realising 141 ed ed manpower for Indian industry
Task Force. Task were mobilized from Department n annual basis through meetings ly in the trans-disciplinary areas, Resource Development Centre” agency for technology mission approved for implementation for approved ogrammes, out of 24 received, tus of deemed university for university deemed of tus re. so hs en sind the assigned been has ision hip of the DG-CSIR and Co- and DG-CSIR the of hip egion. Based on interactionson Based egion. and financial progress of 51of progress financial and with the culturestraditional ing UGC-CSIR joint test, i.e.test, joint UGC-CSIR ing of the country. In addition, In country. the of R) of Rs.133.00 newfor lakh to 25 next years R&D for of gar Prize etc.gar Prize ember 2004. This This 2004. ember task force f ad eet prospective select and ify nme o hg quality high of number e oas wih ae been have which posals, development such as CSIR Prasad Mukherjee (SPM) Mukherjee Prasad Science Training (CSIR- Training Science C) on regular basis for basis regular on C) ss hog quarterly through asis ois n facilitated and tories m o Yuh for Youth on mme
Hqrs Activities CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Hqrs Activities possibilities for consideration of core-competencie of consideration for possibilities re-exami thorougha for committee a constituted has DG-CSIR, on the basis of action arising out of perf CFRI AND CMRI OF CORE-COMPETENCIES THYAGARAJAN COMMITTEE FOR OFCONSOLIDATION Ramasami Committee drought, for CFRI, and Dhanbad, S Technology, & Research, CommitteeThyagarajan for consolidation o Science Medicines, of System Petroleu Indian Depa and etc. Petrochemicals, Family & Health and Forest, & Environment Chemical of Ministries The Division represented CSIR on various committees INTERMINISTERIAL LINKAGES biophysics. molecular and biology structural of award for the year 2003-04 for his outstanding & su Molecular Biophysics Unit, lISc., Bangalore, was ho and outstanding contributions in science biological Indian of meeting annual the at year each given be theand of founding R father Structural Biology & D p of pioneer G.N.Ramachandran, Prof. of memory fond CSIR has excellen for instituted a award gold medal & TECHNOLOGYBIOLOGICAL SCIENCES GOLD I FOR G.N. PROF. MEDAL RAMACHANDRAN EXCELLENCE oilseeds.on Mission Corporation and national laboratories for all progr n CR bt stae a Dabd cnieig thei considering Dhanbad, at situated both CMRI and nutrient management protocol for nutrient management controlfor protocol of pre-har spouted bed continuous Dryer of 200 kg/hr capacity oil; mustard pungent of production for chamber and capacity day per Tonnes 6 of Expeller Oil Modem of the significant outputs of these R&D programmes are elh eeis crig rm osmto o soybea media. print of electronic and through consumption from accruing benefits health The division coordinated the evaluation study with with study evaluation the coordinated division The Ten R&D programmes were declared as completed durin completed as declared were programmes R&D Ten The The division has funded and coordinated the generic 142 ormance appraisal of laboratories, ammes funded under Technology noured with the first gold medal stained stained contribution in the area s & technology. M. Prof. Vijayn,
area in India. The The is to in award area India. ce in biological cesciences thein biological in for for groundnut; and Improved of the two laboratories, CFRI laboratories, two the of vest aflatoxin in ground-nut.in vestaflatoxin Science Congress for notable for Congress Science nation of the charter and the and charter the of nation (a) Design and development f f core competencies of CMRI with water cooled cage bars cage cooled water with of the Government, namely design and development of development and design M/s. Agriculture Finance Agriculture M/s. promotion of soybean for rotein chemistry research chemistry rotein rtment of Biotechnology, of rtment aog eea public general among n rsuc endowments, resource r etc. inii ad Industrial and cientific ad aua Gas, Natural and m g the year. Some ofSome year. the g N proceedings of two days conference were brought out brought were conference days two of proceedings main streams in management knowledge and networking on overview multi-disciplinary a provided event The The last the session of was Panel level Discussion. the About raised 180 de further which sessions, the Sci industry. and academia to institutions R&D from papers was made in a manner, which fairly represent knowle and engineering knowledge markets; knowledge sessions, namely teams; knowledge knowledge sharing Research. General Director Ganguly, N.K. Dr. by delivered was SA cniud t atvte amd t ulig an synergies and leverage CSIR's building capabilities in at core overse major its aimed all and CSIR between understanding activities its continued ISTAD AFFAIRS TECHNOLOGY & SCIENCE INTERNATIONAL 3.2 org networking’. (RDPD) CSIR well, as real 'Value of theme the with conference management year this continuation, In - 2004R&D MANAGEMENT CONFERENCE divisio The performance. committee. this of functioning and activities programmes, as as shown: countri various to visits The Malaysia. Bangladesh, Russia, South Korea, Mauritius, SouthThailand, Afr globe in like USA, Germany, France, Japan, UK, Chin multilate & bilateral 25 as many as with interfaced This year around 36 abstracts were received. 23 pa 23 received. were abstracts 36 around year This The keynote address was given by Dr. A. S. Abhirama S. A. Dr. by given was address keynote The IETRT (ISTAD) DIRECTORATE 143 areas of S&T interest. The division legates attended the conference. dsuso ad participation. and discussion ral partners located across theacross located partners ral es during the current year are year current the during es ed cross-section of intelligentia ica, ica, Sri Lanka, Canada, Oman, a, a, Italy, Singapore, Australia, entists of eminence chaired eminence of entists , Indian Council of Medicalof Council Indian , as S&T partners to developto partners S&T as ization through knowledgethrough ization . innovative and intriguing and innovative pers were presented in six in presented were pers ; ; knowledge management; friyn bigs of bridges fortifying d to the participants. The nzd h sxh R&D sixth the anized dge future. Selection of Selection future. dge n, while themeaddress while n, i codntn the coordinating is n
Hqrs Activities CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Hqrs Activities out of eleven selected at this meeting were from CS from were meeting this at selected eleven of out Deputy Vice Minister for Education & Research chair wire, wire, (BGI), (BGI), China to carry out joint research Beij in the with are Understanding of Memorandum a signed IGIB CHINA storage. CSIR participated in the CSIR3in participated BUL GARIA aeronautics biotechnology, of areas oceanography. the in projects impl for scientists of exchange through partnership Febr in Understanding of Memorandum a signed (CNPq) & Scientific of Council National Brazilian and CSIR BRAZIL BILATERAL CO-OPERATION ed tDli n 1 on Delhi at held food technology, mapping of sub-surface Geoelectric sub-surface of mapping technology, food st o.0. ertr,DT n Po. ae Vlv Bul Velev, Kamen Prof. and DST Secretary, Nov.’04. rd Meeting of the Indo- Bulgarian joint S&T Commissio Meeting of the Bulgarian Indo- 144 a a of Genomics and Bioinformatics. Technological Development Technological IR labs. in the areas of areas the in labs. IR ed the meeting. Five projects ementation of joint research joint of ementation ing Genomics InstituteGenomics ing nw aeil and Materials new , uary 2004 for scientific for 2004 uary structure and energy and structure garian nano- n A three-member delegation from Academy of Finland ( of Finland from Academy delegation A three-member FI NLAND S&T Cooperation. (ASRT) Technology Research & CSIR-the ongoing under implementation for approved Mi a Electronics Research Institute (ERI), Cairo, “Establishing Egypt” proposal project collaborative A EGYPT Bei Management, and cooperation. Policy of Institute & Delhi New current current Drug year. and Polymers Catalysis, Environment Materials, Advance of Promotion the for Centre French Indo the coll ongoing under scientists CSIR of visits Eleven events. extreme Forecasting (vi) monsoons; Indian and Aerosols (v) and meteorological in assimilation Variational (iv) va Monsoons Intra-seasonal-interannual and the (iii) systems;convective of cycles Life Carbon in Central and Asia;fluxes India (ii) (i) fol the out carry to proposed is it programme, this Director Director General, Dr. Bernard Larrouturou) to delegation CSIR ten-member a of visit the during signed on research for programme Indo-French an launch to Centre National CSIRCNRS MoU and (French A between FRANCE that CSIR may hands for join Finland AKA, and resea networking and research schemes by funded HRDG. It the purpose, wherein presentations were made interac on An CSI partnership. scientific of possibilities Nov.’04 with an aim to understand R&D system in Ind There one is There ongoing project also in the area of S& 145 iemeig a raie for organized was meeting tive between ERI & CEERI, has been lowing projects: lowing on 28 aborative projects funded by funded projects aborative R activities & its international T Policy between NISTADS, between Policy T rch rch partnership. rm NS hae b its by (headed CNRS from ia/CSIR and also to explore oceanic systems; oceanic r-arcto Fclt at Facility cro-Fabrication d Research in the areas of areas the in Research d is now in principle agreed riations experiment; riations The Academy of of Scientific The Academy AKA) visited CSIR AKA) visited on 23 weather and climate was climate and weather th to pae uig the during place took s September 2004. Under ig Cia ne this under China jing, for Scientific Research) for Scientific rd
Hqrs Activities CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Hqrs Activities Juergen Kurths, Institute of Physics, Potsdam Unive Potsdam Physics, of Institute Kurths, Juergen JAMSTEC), JAMSTEC), on poet n oi wseae tetet between treatment wastewater Toxic on project joint JAPAN Two research projects under the DST-DAAD PPP, DST-DAAD the under projects research Two processing”. Gel differen on coatings emissivity low of “Development Technology, Stuttgart, Technology, Germany on the invitation fr of University Hunger, Michael Prof. and IICB, from microorganisms, and concrete structures.concrete and microorganisms, immunosenso of areas the in Programme Exchange DAAD CSIR-Humboldt reciprocity research award and (RRL-Jammu) Earth Sciences are (NGRI) ongoing. Adlershof) have been approved for implementation. for approved been have Adlershof) for Eco-friendly Catalytic process (IICT & Institut Germa Darmstadt, University Technical & (CEERI MEMS Under the CSIR- FzJ Cooperative Science Programme, GERMANY CSIR–CNR, Italy made excellent progress with the su the with progress excellent made Italy CSIR–CNR, ITALY been approved have Germany) Mainz, Mainz, of Univ. and Freiberg.) development of novel sensitizers ( R Super-hydrophilic Sol-Gel coatings (RRL-T & Institu visited India against four visits of CSIRscientist of visits four against India visited Institutes. CNR with out carried jointly were (NIO) Metaboli Bioactive and (IGIB) Polyphenols Bioactive onprojects Somatic hybridizati joint Three Venice. hr hv be svn iis ne te non proj ongoing the under fol the in programmes S&T various under implemented visits seven been have There GR etrd no eerh olbrto wt ZAE, with collaboration research into entered CGCRI Three scientists each from India and Germany exchan Three joint projects in the areas of Chemical Scien Oceanography Materials (NIO Instituteand of Observational Research for G NL and (NCL
eatet f hmsr, oy Isiue of Institute Tokyo Chemistry, of Department 146 for the year 2005 was awarded to Prof. s to Italy.tos e e for Angewandte Chemie Berlin- RL-T RL-T & Institute for Pharmazie, on by protoplast(NCL), fusion by on
ces (NCL), Bioactive molecules om IIP. Six scientists from CNR, Italy CNR, from scientists Six te fur keramische Werkstoffee, in the area of Photo-catalytic, of area the in rsity, Germany on invitationon Germany rsity, Stuttgart, Instt. of Chemicalof Instt. Stuttgart, t types of substrates by Sol- by substrates of types t tes from benthic organisms benthic from tes two new projects on Optical ER ad nvriy of University and NEERI ccessful completion of the of completion ccessful for implementation.for ged ged visits under the CSIR- lowing areas: lowing cs ih aa being Japan with ects ny) and New Materials New and ny) aen Gray for Germany Bayern, s eais marine ceramics, rs, lobal lobal Change, recovery. okhp i te ra o oengah, ete and leather implementation. for recommended oceanography, of areas the in workshops Science and Technology), Technology), and Science Technology) (RRL, Thiruvanthanpuram & National Inst ehooia Coeain ed n 23 on held Cooperation Technological At the fourth meeting of the Joint Indo-Myanmar wor MYANMAR Institute National and Okazaki). Biology, Nati & (CCMB Nagpur Biology Molecular and NEERI, Science,Tsukuba) between MoU an 3 Coo (NTNU) Institutional Technology & of Science University Norwegian of programme Indo-Norwegian Under NORWAY 2.5 core). tune the to Foundation Science Dutch the by funding with collection of benthic samples. The detailed p was (NIOO) Ecology of Institute Netherlands and NIO A major programme on Benthic biodiversity across ox NETHERLANDS under this arrangement. been accepted for training in the areas of medicina labs. Two Nepalese scientists from Royal Nepal Acad train to offered CSIR 2004, April 7-8 during Delhi co joint Indo-Nepalese the of meeting secondthe At NEPAL re the mid-term in participated from NIO scientists Septembe 23 to 16 from held was Sea” Andaman the in India-Myanmar collaborative project “India-Myanmar rd Feb., 2005 for a major joint project on reservoir reservoir on project joint major a for 2005 Feb., Under Under the ongoing activities, a mid-term review of Advanced Materials for Environmental Applications Environmental for Materials Advanced 147 rd eebr 04 he CI poet / projects CSIR three 2004 December l l plants at RRL, Jammu & CIMAP roposal roposal has been worked out for view meeting. view Nepalese Scientist at variousat Scientist Nepalese Newat held S&T on mmittee ygen minimum zone between emy of S&T (RONAST) have king king group for scientific and of Euro 4.4 lakes (about Rs. (about lakes 4.4 Euro of oeig o ehne oil enhanced for modeling the the Myanmar component of itute of Advanced Industrial joint oceanographic studies initiated in October 2004October in initiated r 2004 at Myanmar. Two Myanmar. at 2004 r signed an agreement on agreement an signed od ehooy were technology food nl nttt o Basic of Institute onal eain NR and NGRI peration, o Materials for under
Hqrs Activities CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Hqrs Activities eeat rtcl ehooy i a ogig collabo ongoing an is technology” TWT critical Helix relevant Efficiency High Ultra-wideband of “Design SOUTH KOREA IICT and between of RRL-Bhubaneswar, University Wit Cooperation Programme in the area of low temperatur of Cap and University (IICT agents antimalarial and of Witwatersrand), Catalysts (NCL & University of C drugs (NCL & University of Capetown.), artificial I S&T inter-governmental the under projects CSIR Four SOUTH AFRICA under Russia visited Programme (ILTP). scientists CSIR Six Projects. f angles sensitivity and security from cleared were Institu Russia, and United GRI, Troitsk Petersburg, Ru RAS, SB Chemistry Inorganic of Institute Moscow, projects five and NGRI Russianfrom with Institutes Six projects, one in the area of catalysts (NCL & I RUSSIA programme. this CSIRunder visited On instrumentation. medical and vents hydrothermal the in Cooperation S&T Inter-Governmental the under (iii) ‘Biomarker Response in Estuarine/Coastal Fishe Estuarine/Coastal in Response ‘Biomarker (iii) Oceanic in Processes the of C West ‘Variability (ii) (i) ‘Reconstruction and ‘ReconstructionProductivity Past Changes and in (i) cooperation: S&T i inter-governmental Portuguese been have NIO by submitted projects following The PORTUGAL eie, hr ae w o-on poet udr the under projects on-going two are there Besides, There were four visits under the ongoing b ongoing projects under the visits four were There monitoring monitoring and management' with CIIMAR. Archipelago’ in collaboration with University of Az with University collaboration in Archipelago’ fi Instituteinvestigation of of with collaboration 148 nstitute of Catalysis, Novosibirsk) ntelligence (CBRI and University or implementation under ILTP under implementation or te of Physics Moscowof Earth, apetown) and antituberculosis like Oil & & GasOil like Res. Instt RAS, etown) have been have been etown) approved. aie rjc udr MoU a under project rative oast in India and the Azoresand oastIndia in h Itgae Ln Term Long Integrated the e oxidation and nano metals cooperation in the area of area the in cooperation Portugal and India etween sheries and Sea Sea (IPIMAR);and sheries areas of marine pollution, marine of areas ssia, VNII Oceanology, St. Oceanology, VNII ssia, watersrand. s for pollution for s cue udr h Indo- the under ncluded sinit rm Portugal from scientist e of Arabian Sea’ in Sea’ Arabian of ne-oenetl S&T inter-governmental ad eeomn of development and s ores; Metrology THAILAND collaboration. of consu and aromatic plants production in the on region, research programs at training specialized get to Cooperat International AVRDC’s from researchers Two TAIWAN were trained at CFTRI in a custom made training pro link scheme for a period of three years.three of period a for scheme link op fibre emitting UV using water of decontamination this this year. c project Srilankan of visit One biotechnology. in of environmental biotechnology under the Indo-Srila an have Lanka Sri Kelaniya, of University and NEERI SRI LANKA this year. under sides both from visits exchange Three Korea. National Seoul Physics, of School and CEERI between transformations over catalytic molecules. catalytic over transformations partnership in the area of managementexpe are of chromiumvisits The i I 05. – under 2004 Programme networking selected were 11 of out scientists CSIR Two UK finalize to NIMT visited NPL from scientists Also, identificati and PoCthe under metrology of discussions area the in cooperation for NPL visited (NIMT) Instit National from delegation Thai A photometry. areas for identified mutual cooperation were electr NPL S&T. inst two in the as identified were Thailand Metrology, co-operation on committee joint the of Two scientists Two Srilankan from the government analys GR ad nvriy f ed iiitd jit res joint a initiated Leeds of University and CGCRI
was identified as one of the areas for joint co-ope 149 oordinator to NEERI took placetook NEERI to oordinator CIMAP, and explore possibility icity, icity, mass & related quantities, the areas for joint cooperation. joint for areas the n ore processing and chemical itutes in this area. The focus The area. this in itutes gramme gramme on “Food Analysis”. between India and Thailand. and India between nka nka Cooperation programme this programme took placetook programme this ute of Metrology, Thailand Metrology, of ute ongoing project in the area the in project ongoing d- K on scientists Young UK ndo- cted to establish CSIR-UK establish to cted pin f eiia and medicinal of mption tics under British Council British under tics University (SNU), South (SNU), University ion Office visited CIMAP visited Office ion ts Sri department, Lanka, n f ra fr mutual for areas of on Ntoa Isiue of Institute National & ration at the first meeting ac poet on project earch
Hqrs Activities CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Hqrs Activities New Delhi. The was focus on:The Delhi. New Inn Technology of “Management on workshop two-day A ASEAN REGIONAL S&T COOPERATION design. t in Measurement, partnership which is research of direct joint relevance for to USA NAL’s University, up-scaling successful research work upto commercial upto work research successful up-scaling prom the ofchain Innovation the links various “Managing to mechanisms on ASEAN from counterparts their parameters. dat series time real the providing are moorings The four TAO and one ADCP moorings (supplied by PMEL) d • • • Glasgow) Glasgow) on project NML’s and London) Research, Medical on project CDRI’s programme. with a focus on industrial research. a on focusindustrial with CSIR possible for CSIR DG, with discussion detailed and air quality under a under MoUMinistry quality of between air Env and CRRI was chosen as the nodal agency in India for mo USA Institutions. UK A A Memorandum of Understanding was signed between NA Prof. Julia Higgins, Vice President, The Royal Soci Royal The President, Vice Higgins, Julia Prof. The The main objective was to share experiences between management. technology effective IPRin of role transf laboratories; research technology and R&D supporting for strategies of innovation creation growth and the facilitating NIO and Pacific Marine Environmental Lab (PMEL), US DI n NL agd w poet udr noU Scie Indo-UK under projects two bagged NML and CDRI are the new beginning of project mode partnerships partnerships mode project of beginning new the are yoatru TuberculosisMycobacterium 150 major programme on Aerospace Methane emission (university of (university emission Methane a on atmospheric and oceanic and atmospheric on a right from development and from development right delling of delling vehicular emission driven enterprises;driven e ra f dacd Flow Advanced of area he - Royal Society partnershipSociety Royal - ization”. ironment and ironment US-EPA.and ety visited CSIR and had a had and CSIR visited ety scientists India from and uring Sagar Kanya cruise. A A successfully deployed Ntoa nttt ofInstitute (National r rm universities/ from er t ST particularly S&T, ote ovation” was held at held was ovation” between CSIR andCSIR between L and Florida State c Network nce conferences/workshops abroad. conferences/workshops curre the During experts. applicants) non-CSIR Scientists were as awarded partia 2 and fellowship under hig for 64 programmes, exchange bilateral under 130 business part for 4 cruise, for on 24 conferences/seminars, deputed were 476 around these, Of 2004-05. pr different under deputed were scientists CSIR 817 HUMAN RESOURCE THROUGH TRAINING Commission’s from the ASIA funding European UK with collaboration with School of Chemical Engineering, European Union’s A under collaboration for approved irrigation and potable for groundwater of treatment the Netherlands. The project will be coordinated by coordinated be will project The Netherlands. the European the from participants 4 and (NSDRC) Centre Nation and (CIFE); Education Fisheries of Institute Energy Tata NIO; from apart India from participants Union for funding under the VI framework programme. submitted by Tata Energy Research Institute (TERI) A project “Assessing entitled impacts of TBT (tribu EUROPEAN UNION S&T COOPERATIONMULTILATERAL for the award of thefor award 200 for Raman research fellowships s CSIR six of Nominations 2004-05. during countries various from selected fellows research Raman Seven FELLOWSHIPS RAMAN RESEARCH FELLOWSHIPS networking.international and building with year 817 visits CSIRby overseas the scduring The growth of foreign visits by CSIR Scientists con Scientists CSIR by visits foreign of growth The A project proposal entitled “Development of a low c low a of “Development entitled proposal project A 151 has been approved by European tylin) tylin) on multiple coastal uses” ientists for capacity/capabilityfor ientists development, 78 for training, for 78 development, Queen’s University Queen’s University of Belfast, TERI, Goa. TERI, l l financial assistance to attend 5-06. al Ship Design and Research and Design Ship al cientists have been approved been have cientists purposes” of NML has beenhas NML of purposes” ogrammes by ISTAD during ISTAD by ogrammes her studies/assignments, 39 studies/assignments, her CSIR labs visited their host their visited labs CSIR Research Institute; Central Institute; Research SIA Pro Eco Programme SIA Eco inProgramme Pro tinued and reached a peaka reached and tinued Union, Italy, Sweden and Sweden Italy, Union, The project involves three cpto i international in icipation ost technology for in-situ for technology ost t er 24 ot f 655 of (out 254 year, nt Pro Eco Eco Programme. Pro
Hqrs Activities CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Hqrs Activities WORKSHOP ON WORKSHOP DISPUTE INRESOLUTION TECHNOLOGY A special function was organised on World Intellect World on organised was function special A DISTRIBUTION PRIZE CHILDREN- SECOND CSIR DIAMOND JUBILEE INVENTION AWARDS FOR SCH Head, IPMD, CSIR. Anand and Anand, Dr. H R Bhojwani, Emeritus Scienti Dawn International, Ms. London. Eminent Geneva; Indian Speakers were Centre, Mediation and Arbitration Goddar, Boehmert & Boehmert, Munchen, Germany; Mr. Promin resolution dispute technology in agreements. them enable to and IPR in Mediation and Arbitration medicinal plants plants CIMAP.at medicinal carryout to TWAS by fellowship the awarded been has Dr. (Mrs.) M.A. Osman of Medicinal and Aromatic Pla tores their carryout CSIR- Fellowship awarded been Myanmar, Mongolia, Kenya, Egypt, from Fellowships) and 418 Indian patent applications during 2004-2005 applications during patent 418 Indian and CSIR continued to maintain its position dominant in CSIR IN PROTECTION IP DIVISION MANAGEMENT PROPERTY INTELLECTUAL 3.3 During the year 2004-05, ten candidates, (five each TWAS FELLOWSHIP at FICCI, Federation House, New Delhi for the distr the Govt., R&D institutes, law firms, the Govt., R&D IPfirms, and institutes, profes law property rights’. About 80 representatives from pr a ‘Arbitration was workshop the of theme The Delhi. April on -IIPD FICCI and WIPO with jointly CSIR by on A Technology in Resolutionworkshop ‘Dispute The AGREEMENTS h wrso epsd h priiat t te world’ the to participants the exposed workshop The Under Under the TWAS Fellowships for Postdoctoral researc (IPMD) 152 for Postgraduate and Postdoctoral ivate ivate and public sector industry, sionals sionals attended the workshop. ibution ibution of prizes of the ‘Second IP arena by filing foreign 500 IP arena by filing ual Property Day (26 Day Property ual . Mr. Pravin Anand, Attorney, earch in in Laboratories.CSIR earch ent speakers were Dr. Heinz ent Dr. were speakers nts Research Institute, Sudan nd mediation in intellectual in mediation nd st, CSIR and Mr. R K Gupta, to plan their strategies on strategies their plan to 26-27, 2004 at FICCI, New FICCI, at 2004 26-27, J. Christian Wichard, WIPO her advanced research on research advanced her greements’ was was organized greements’ Nepal and Nigeria have Nigeria and Nepal h and advanced training son, os & Co. & Rouse Osborne, cret rcie in practices current s th April) OOL on 26 invention jubilee diamond third the announced CSIR CHILDREN-2004: THIRD CSIR DIAMOND JUBILEE INVENTION AWARD FOR SCHO the with interaction lively and had awardees the by who attended the function shown keen interest in th from CSIR and Directors of Delhi based CSIR labs, p teachparents, attended by function was The skills. only they have intellectual and innovative capacity Inventor’ Inventor’ for his invention Writer’.‘Braille b for WIPO Wichard, Christian J. Mr. by certificate prese also was Invention Award-2002 Jubilee Diamond t Pathak, Madhav Masterinventions. their explained The awardees were presented a plaque, certificate a th for selected were inventions eight only given be ch distributed by Dr. school R A Mashelkar, DG-CSIR. Out for of awards invention jubilee diamond CSIR Court of Appeals of the Circuit, USA. incl Federal H Sir This Japan. and panel Europe a US, the from from industries drawn was faculty The enforcement. IP and CII. The theme of the Workshop was to address t An International workshop on ‘IP was Litigation’ jo INTERNATIONAL WORKSHOP ON ‘IP LITIGATION’ solution. management internet an through intelligence competitive using this tool would help in reviewing patentst analysis from and management a co risk patent a – Doors CAM issued and applied for in the US and around the wor opportun commercial unique the determining for tool with M-CAM Doors to provide access to the patent ri of licensing its IP internationally. The agreement CSIR has an signed agreement with M/s M-CAM Doors I M-CAM DOORS TRAINING 26 September on announced foundation CSIRwere day, cate various the for selected were inventions seven DG-CSIR lauded the efforts made by these young awar young these by made efforts the lauded DG-CSIR th 2004. April Out of 442 proposals received from va 153 has also resulted in a partnership mmercial application perspective but also have good entrepreneur nd nd cash prize. They have briefly e model / flow charts displayed ers of awardees, invited guestsinvited of awardees, ers ugh Laddie, Chief ugh of Laddie, Judge the articipants of workshop. Those eing the ‘Outstanding Student ‘Outstanding the eing intly intly CSIR, organized by DSIR e various categories of prizes. of categories various e m. total number of sixty prizes to ld. ld. A one-day training on ‘M- ois fpie. Te prizes The prizes. of gories he he emerging issues related to sk management analysisand he first prize winner of CSIR of winner prize first he rwe ad o id P risk IP find to and browser ds ug adl Rader, Randall Judge udes awards for school childrenschool for awards ities and threats of patentsof threats and ities nted the WIPO medal and nted WIPO the medal ool’ was held. The use ofuse The held. was ool’ , 2004. , lrn. h pie were prizes The ildren’. rious rious parts of the country nc. nc. USA to assist CSIR in f mnn jde and judges eminent of dees and said that notthat said and dees OL
Hqrs Activities CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Hqrs Activities ••• Some of the achievements under NMITLI include: NMITLI under of achievements theSome systems. targets delivery drug advanced new and turbine; wind axis horizontal cost offic novel implants; medical to systems expression to of carbohydrates composites; defunctionalisation a to alkane of functionalisation molecules; biotech micr catalysts; nano-material to modeling mesoscale to crystals liquid from ranging areas diverse cover m realize R&D to order in projects ongoing 20 to proactive provided Besides projects. focussed as ideas by a federal government. During the year, TNBD cat public-private-par of domain the in model role a as the innovation space. It enjoys an unprecedented br which has emerged as a unique initiative of the gov CSIR operates New Millennium Indian Technology Lead NMITLI UNDER PROGRESS Cus undertaken and managed and by the TNBD during the (URDIP) year Products Evaluation Unit (CSEU) directly under its charge. Information of Development offunctioning two u CSIR also facilitates division of activities development business overarching and Initiat Technology Millennium Leadership Indian New Divi Development Business and Networking Technology BUSINESS AND NETWORKING TECHNOLOGY 3.4 pharmaceuticals. and drugs to industrial various in implication its and 1/1/2005 and explained the Indian position on amendment in t Charge) for Science & Technology and Ocean Developm Patent Court of Shri England. Hon’ble Kapil Sibal, • New New TB Therapeutic Molecule – IND filing and cleara clinical trials. The molecule is currently undergo currently is molecule The trials. clinical during the year. The IND was cleared by the regula ( Drug New Investigational an studies, pre-clinical Afte tuberculosis. of treatment the for discovered EEOMN DIVISION DEVELOPMENT 154 nits namely Unit for Research nits& Unit for namely Some of the important activities Minister of State (Independent ernment, ernment, carving out a niche in the objectives. These projects These objectives. the sectors and especially relating especially and sectors and image and image and is looked upon biodegradable plastics; novelplastics; biodegradable vne nn-aeil and nano-materials dvanced e computing platform to lowto platform computing e alysed alysed and developed 11 new eetaie pwr packs; power decentralized launched initiatives tnership he he patent laws effective from r carrying out the extensivethe out carrying r SR n h ohr TNBD other. the on CSIR ing clinical studies. This is This studies. clinical ing n mres o cne to cancer for markers and are summarized hereunder: booia cnesos to conversions obiological IND) application was filed was application IND) ent inaugurated the session tory tory authorities for Phase I ive (NMITLI) on ive (NMITLI) one hand ership Initiative (NMITLI) ngmn spot was support anagement sion (TNBD) steers thesteers (TNBD) sion nce: nce: oe Satisfaction tomer A A new molecule is ••• ••• ••• • • • munity. software is poised to be competitive globally and a doma the in success Indian mark to 2004 14, July on bioinformatics was launched by Hon’ble President of test the Linux Cluster Version of Bio-Suite.of Version Cluster Linux the test m node 8 same The locations. different at software mac node 8 of numbers 12 todevelop endeavouring is and B are being tested on these machines. CSIR in node machine by interconnecting with such four 32 n would It ready. processor is 32 system A world. the whi technology optical on based FloSwitch developed interconnect node independent an forming processors tropical features. region A powerful computer has known the of version modified a - B Software (iii) tropica account into taking software new a - A ware which has three distinct components: (i) Parallel p BioSuite®: of Launch system. livery alon developed been also have targets drug new Some fro drugs two or one replacing by therapy drug four It observed. been has recurrence no and months two cle toxic, less is drugs), present the with patible last 40 years globally. The molecule works through tube new a developing in achieved success first the tion: tion: gen for mentha and tea in genomics functional Using modeling: soscale pred weather and monsoon strengthening and Refining - Niche pathway engineering in tea:in engineering pathway Niche - obtained: been express targeted enhanced for promoters and tagging volved with key metabolic pathways and to develop n - been filed. been have been gene developed. Two patents novel covering the prom dependent element – two and directional vectors: expression Gene developed; been has echin biosynthetic pathway haveA kit cloned. been world. the in time first the for developed been has The effort was to use the latest technologies for c for technologies latest the use to was effort The NMITLI has supported a project on mesoscale modelli mesoscale on project a supported has NMITLI h Bout® a estl pral sfwr for software portable versatile a BioSuite®, The an artificially designed synthetic promoter, bi- promoter, synthetic designed artificially an 155 tea database profiling catechin content tea profiling database ars the total infection within infection total the ars rocessor (ii) (hardware); Soft- ffordable ffordable to the Indian com- association with IMD (DST) combination therapy (com- been developed been developed with eight India Dr. APJ Abdul Kalam software incorporating the incorporating software achine will also be used to used be also will achine be extended to form 128form toa extended be rculosis therapeutic in the in therapeutic rculosis ode ode machines. Software A l region dimensions; and dimensions; region l in of bioinformatics. The bioinformatics. of in fits well into the present the into well fits ew ew technologies for gene m the (present) cocktail. (present) the m ion. Specific leads have leads Specific ion. hines for validating the validating for hines Genes involved in cat- in involved Genes gwith a novel drug de- drug novel a gwith ch is as good as any in any as good as is ch ed by an indigenouslyan by ed haracterizing genes in- genes haracterizing for for catechin estimation e expression modula- expression e oters developed have iction based on me-on based iction xrsin vectors expression ng
Hqrs Activities CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Hqrs Activities in hand during the year.hand in during and property contract worth Rs. 400 crore contrfor exe were agreements license 100 Over stakeholders. indu level national p with marketing linkage organic render and maintained to development continued business for also laboratories Division The CSIR. with mutual term long a develop to keen is P&G domains. Maste undertak for theInc. with (MCA) and Gamble Procter a negotiated has division The felt. been have as well as demand for CSIR‘s The knowledgebase. res sp was division contemplating to organize a CSIR-Indus out bringing companies; international as well as making them more customer friendly; increasing one- t in themchangesso as the toin with align guidelines initiatives re undertaking new were: these among several Major development. taken has Division The BUSINESS AND DEVELOPMENT MARKETING OF KNOWLEDGEBASE issues. whole foste to areas focus five these between initiatives GRA is embarking on the next stage of integrating a pr groupto set-upof the core pursu member designated intellectual the of management of issues the and Indigenous Knowledge to focus on critical issues su the World Bank. The GRA and World Bank have embark and Climate Change through an Assessment of Adaptat project in Gujarat and the other on Addressing Vuln pr major two formulating in role lead the took CSIR response various Among opportunities in a of variety specialist and fields implementation. project and Allia large a as together implemented is to respond to development funding ag working of record track a th that ensure the opportunity area afforded explore to is members to practice into put been has fusion Fraunhofer-Gesellsch Netherlands; SIRIM-Berhad (DTI); - Malaysia CS and VTT - Finl India; Institute - CSIR Technological Australia; - CSIRO USA; - Battelle ex transfer technology and fields technological and Itgood. enco pool global for knowledge of a global es is which GRA, the of member founding the CSIRis GLOBAL ALLIANCE RESEARCH (GRA) 156 across a wide geographic spread, ch as validation, benefit-sharing r creative synergies to addressto synergies creative r the external policy settings andthe policy external act R&D consultancyand were nd nd implementing cross-cutting mpasses a breadth of scientificmpasses breadth a erability erability to Climate Variability oposals; one for the Kalpasarthe for one oposals; to-one interaction with Indian s To establish of cooperation. and. A process of technology ults of these proactive efforts cuted for CSIR’s intellectualCSIR’s for cuted viz. members, its of pertise try try meet to awarenesscreate the of expertise technical e e this initiative further. The further. this initiative e ca pbiain ec The etc. publications ecial Claoain Agreement Collaboration r ing projects in diverse R&D diverse in projectsing tablished around the visionthe around tablished ty soitos n other and associations stry pry ihs CI i the is CSIR rights. operty ency expressions of interest c, n o te strategies the of one nce, R Suh fia Danish Africa; -South IR ly rewarding relationship rewarding ly ion Issues and Options for f - emn; N – TNO Germany; - aft e oan f business of domain he ed ed on a new oninitiative iin f h marketing the of vision f nwegbs. It knowledgebase. of ocie sitne to assistance roactive md t potential to made s and inclusion of these in the guidelines. TNBD Divi TNBD guidelines. the in these of inclusion and protection will be implemented through co-locat working out resourc entities; co-sharing / laboratories CSIR to business proximate shore off of up setting knowledge alliance; setting up of section 25 compan new two, phase the in While (ii). and (i) point at two phases. The phase comprise of one will impleme GB the by approved been have recommendations These transfer and utilization of knowledgebase; and (iii that have not been implemented; (ii) modifications and pertain to: (i) thosereiterating recommendatio cla been have Committee the of recommendations The matter other mechanis any upon dwell and and schemes; incentive models facilitative evolve S strategies; scenario, s R&D ABM-2004; by made global suggestions and recommendations emerging the with consonance of of reference the Committee were to: review the p advantageously and guide derive maximum marketing benefit the from revisit the to imperative therefore as India at looking were TNCs and MNCs growth. of hasindustry begun sector. Indian industrial thein Committee. Mashelkar 1 Several developments have sin in enlarged were and 1989 in framed were place in “technology transfer and utilization of knowledgeba 2004, NCL t Committee of Chairmanship theDirector, under (ABM) meet Business Annual the of out Arising TRANSFER TECHNOLOGY AND UTILIZATION OF KNOWLEDGEBASE FOR CSIR GUIDELINES REVISITING THE FOR COMMITTEE etc. Korea, South Dubai, Singapore, Republic, Sri from clients other includes also list The etc. Lanx Procter and Gamble, Unitel Scios, Technologies, Fri ESCOM, FAO, Bayer, Honeywell, incl Pharmaceuticals, proposals these covering clientele the of Some basically contract R&D. During the year, about fif assessed in the scientists/agen division from security and sensitiv foreign involving proposals R&D The CLEARANCESENSITIVITY AND SECURITY 157 ty ty such proposals were processed. in CSIR guidelines for technology ity ity angle. The proposals covered lanka, Nepal, Malaysia, Kyrgyz Malaysia, Nepal, lanka, ) ) putting in place new initiatives. initiatives namely: setting up of up setting namely: initiatives to recognize R&D an R&D asenginerecognize to ns of the Mashelkar Committee y y scheme; mobility of scientists; tz – Haber Institute (Germany) resent marketing guidelines resent in guidelines marketing details for each of the initiative sion assisted the Committee.the assisted sion se”. The currentlyguidelines n idsra RD centers R&D industrial ing es with industry; and macro and industry; with es ie s a t psto CSIR position to as so lines ntation of recommendations changing scenario. The terms dd uot Ivsa ISIS Invista, DuPont, uded as referred to by DG,CSIR. by to referred as s rcmed enabling recommend ms; ce taken particularlyplace, 993 with the inputs of the of inputs the with 993 o review the guidelines onthe guidelines o review ssified in three categories three in ssified a major R&D hub. It was It hub. R&D major a is ee xmnd and examined were cies SR a cntttd a constituted had CSIR uggest new marketing new uggest o ipeetto in implementation for nhna Committee inghania s, el Helicopters, Bell ess,
Hqrs Activities CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Hqrs Activities umte i Jl 2004). July in submitted cdmcas n idsr dvlpd n mitis n maintains are:ones Significant products. and developed industry and academicians produc IT added value developing of quest in URDIP, (URDIP) OF INFORMATION PROD UNIT & RESEARCH DEVELOPMENT FOR Divisi TNBD CSIR. DG, theby matter other assigned constitute governance; its sp up take to necessary considered as in committee(s), autonomy full realize in bring to CSIR of By-laws and Regulations & Rules recommendations in a time-bound implem manner;to revisitmap road athe evolve and blueprint a prepare referen of terms The NCL. Director, of chairmanship was Team” Change “The christened committee a manner Phytoinformatics: • to recommendations reaching of first a organizations, funded publicly value to val and Committee systematically undertook assess in-depth studies to 2003 June in environmental benefits arising from up CSIR’s R&D outc set was Kel Minister, Vijay Dr. of chairmanship the under Committee A RECOMMENDATIONS COMMITTEE KELKAR IMPLEMENT TO TEAM CHANGE THE • in-vivo testing data and toxicity. and testing data in-vivo the plants identifying in well-validated terms of c mechanisms. scientific modern via function probably highlighting then and the conditions any of disease mus herbs which through action of mechanism the ing conditions. diseases various for conducted was sis As an effort towards new product development, the i nutraceutica various of development the for studies any content, data or information securely. Its easy Its securely. information or data content, any URDOC take to country resources. bio its the protecting databa help patent will of claims of development monitoring The web-enabled. been p economic and aromatic medicinal, used widely 2000 nearl of claims contains and abstracts database The : : A Document Management System has been t developed On a continual basis, URDIP has conducted phyto-in conducted has URDIP basis, continual Ona
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nac vle f SRs contributions(report CSIR’s of value enhance 158 linical linical studies as well as in-vitro, its kind and made several far several made and kind its The project involved identify- involved project The how traditionally used used plants how traditionally ecific tasks; and attend to anyto attend and tasks; ecific Memorandum of Association, nformation nformation search and analy- omes and S&T activities. The ls and therapeutic products. therapeutic and ls and evolved a methodology on assisted Committee.theassisted on and user-friendly interface user-friendly and ce of the committee are to: are committee the of ce necessary amendments to amendments necessary h poetas involved also project The y 10000 patents granted on patents10000 granted y ts benefiting professionals, tsbenefiting ent the Kelkar Committee Kelkar the ent t work in order to controlto order in work t prpit specialist- appropriate e h socio-economic- the ue a, die t Finance to Adviser kar, prpit atos in actions appropriate has database The lants. me o information of umber constituted under the under constituted e n lns and plants on se hat manages formatics UCTS • ee (eeomncto ad optrNtok & II & Network) Computer and (Telecommunication TeNeT been selected for the award this year. Midas Te Commun Communications con Midas constituents. have diverse from that innovations enhancement of national prestige. For the technological year 2004 outstanding CSIR Diamond Jubilee Technology Award recog (CDJTA) CSIR DIAMOND JUBILEE AWARD TECHNOLOGY 2004 compou active and oleoresin flavour, for spices dry Laboratory, technol swing of commercialization Research and (Development Regional to Technology Process aircra transport light multi-role of flight-testing prototype (Design, Laboratories Aerospace National Engineeri for Shield the range); frequency acoustic multi-be using parameters roughness seafloor the of for National Prize Institute of purification); Oceanography and (Developing desalination a sy water for flux thin film composite reverse osmosis membrane t (Developmen CSMCRI to Technology Chemical for Prize Aw Technology four selected CSIR DG, by constituted Awar Technology received. were nominations 23 2004. Techn CSIR the for nominations invited Division The 2004 AWARDS CSIR TECHNOLOGY format. particular in information relevant give and Satisfaction CustomerFeedback Customer Profile CSIto Report record compact on theto disk layout the customer satisfaction feed back received from L upg were Oracle database The 2004-05. year for back activities. It will help provide in depth understa ques A new year. the institute during laboratories/ I and Physical all at initiated was activity CS The CUSTOMER SATISFACTION EVALUATION UNIT (CSEU) URLog level different with securely groups or users other any doc upload/download to lets user create/update, is a complete solution for managing frequently visi frequently managing for solution complete a is well-organi a build toeasy it making annotateURLs is a management system/tool that can add, categori add, can thatsystem/tool management a is 159 nding nding based on the customer feed ft- ‘SARAS’); and the Shield for Shield the and ‘SARAS’); ft- , , 117 nominations were received R. The software was developed stem for quantitative estimation design Project of Information,design tionnaire was designed for CS for designed was tionnaire ofgroup Sciences nformation ng Technology to the team atteam the to Technology ng nds). niern Tcnlg to Technology Engineering echnology and its application raded and updated based on based updated and raded ication, ication, in collaboration with of access privileges.access of databases were changed tochanged databases were m co onig t high at sounding echo am ology Awards for the yearthe for Awards ology arcto ad successful and fabrication websites. favorite or ted ogy for processing fresh/ processing for ogy ards for the year namely: year the for ards hoois v. t. has Ltd., Pvt. chnologies zed collection of URLs. It URLs. of collection zed s eeto Committee Selection ds nizes nizes and honours those ument and share it it withshare umentand Thiruvananthapuram t and scale up of high of up scale and t rbtd ral for greatly tributed -ars designed, T-Madras ze, rearrange and rearrange ze,
Hqrs Activities CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Hqrs Activities JUNIOR RESEARCH FELLOWSHIP (JRF) FELLOWSHIP JUNIOR RESEARCH by Dr. R. A. Mashelkar, DG-CSIR, on 26on DG-CSIR, Mashelkar, A. R. Dr. by 398 awardees till date. The names of the 2004 SSB P NPL Auditorium on 26on Auditorium NPL & Technology & Vice President, CSIR at the CSIR Fou O Science &and Technology Charge) for (Independent Sib Kapil Shri by presented were awards These year. and 2,440 qualified the exam. A total of 1217 candi 1217 of total A exam. the qualified 2,440 and 66,458 candidates were registered out of which 46,4 CSIR conducts CSIR-UGC NET examination twice a year CSIR. function organized at Vigyan Bhawan on 13 Bhawan at Vigyan function organized outsta ten to CSIR President, and India of Minister (SSB) for the year 2003 were presented by Dr. Manmo Shan The prizes/awards. of form the in country, the CSIR gives recognition to scientists Indian for doi AWARD 2004 SHANTI BHATNAGAR SWARUP PRIZE AND YOUNG SCIENTIST t scheme; associateship onLeaders Youth CSIR Program for grants; symposium Visiting organizations; R&D Funding of (SPMF); Extra fellows ResearchMural (EM Associates (RA), Senior Research Associates (SRA) a (S fellows Research Senior of Selection (NET); Test Awards (YSA); Selection of Junior Research fellows include: Award of Shanti Swarup Bhatnagar prizes (S through scientific projects at the national level. level. national the at projects scientific through sc co-ordinates and guides promotes, also It level. . UA RSUC DVLPET RU (HRDG) GROUP DEVELOPMENT RESOURCE HUMAN 3.5 acce (FLL) Loop Fiber-in-Local a optiMA, and system (Wireless WLL corDECT commercialized and developed In In the year 2004, ten scientists were selected for Six scientists were selected for the CSIR Young Sci Young CSIR the for selected were scientists Six The group has a mandate to develop and nurture S&T th September 2004. September 160 th September 2004, the Foundation day of day Foundation the 2004, September th September, 2004. September, The activities of the HRD Group HRD the of activities The ng ng outstanding research work in (JRF) through National Eligibility rize awardees rize awardees were announced 04 appeared in the examination the the SSB Prize, making a total of dates were selected for Junior for selected were dates nding scientists at a glittering a at scientists nding nd nd Shyama Prasad Mukherjee etfc idsra research industrial & ientific RF), SRF Extended Research Extended SRF RF), han han Singh, the Hon’ble Prime SB) SB) and CSIR Young scientist ndation ndation Day function held at ti Swarup Bhatnagar Prizes- Bhatnagar Swarup ti al, Hon’ble Minister of Stateof Minister Hon’ble al, ss system.ss R) schemes at universities/ cean cean Development Science entist Awards during the during Awards entist . . In June 2004 examination hip in Science (CPYLS). Science in hip manpower at the national ae / ofrne / Conference / ravel n oa Lo) access Loop) Local in JRF-NET held on 19 onheld JRF-NET JUNIOR RESEARCH FELLOWSHIP JUNIOR FOR RESEARCH FELLOWSHIP GATE QUALIFIED ENGINE wise split of the result is given below. given is result the of split wise eligible declared were 1223 and Fellowship Research yet to meet and give their recommendations. their give and meet to yet SRFfor for candidates 60 RA. and candidates (Ext) selected and met already have categories subject 11 started from November 2004. Out of 15 subject categ About 2700 applications were received in 15 subject (RA) ASSOCIATESHIP RESEARCH AND SRF EXTENDED (SRF), FELLOWSHIP RESEARCH SENIOR sciences. physical & eligibl be to interview candidates were selected SPM for an 2004 fellowship – by followed test written above99 and have whopercentile to with candidates is open to top 20% CSIR-UGC JRF-NET scholars along nurture budding scientific 2 talent towards year pursuit the o in started was Scheme Fellowship SPM The SHYAMA PRASAD MUKHERJI (SPMF)FELLOWSHIP appeared. 145 JRF-GATE Fellows are at present working in diff in are at working Fellows present 145 JRF-GATE the CSIR scientists with state-of-art R&D facility excellen get scheme this under selected JRFs GATE). Junior qualified GATE the as known is This Ph.D. to candidates with B.E./ B.Tech/ B.Arch/ 20 B.Pharm degre in fellowship research new a introduced has CSIR GRADUATES (JRF-GATE) R eetd302 1 1 2 1217 125 112 614 26 340 Selected JRF etrsi 6 55713131223 133 103 567 55 365 Lectureship The The total number of for registered candidates the C hmsr at ieMtsPyisTotal Physics Maths Life Earth Chemistry th December 2004 examination was 76,060, out of outof which 76,060, was examination 2004 December cec science science 161 and and obtain Ph.D. degree. Around categories. The selection process f f scientific research. The scheme Four Selection Four Selection Committees are ories, ories, Selection Committees in two each in mathematicallife, erent laboratories of CSIR. erent laboratories qualify a specially designed a specially qualify with with top 100 GATE qualified 0 cniae fr R, 23 SRF, for candidates 202 for lectureship. The subject The lectureship. for t opportunity to work with work to opportunity t e e to pursue research leading Research Fellowship (JRF- Fellowship Research SIR-UGC joint examination fr h flosi. Six fellowship. the for e 02 for the GATE qualified GATE the for 02 001 with the objective to objective the with 001 ERING 56649
Hqrs Activities CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Hqrs Activities two two were granted. ou category, grant time one the Under renewed. were 15 schemes were sanctioned out of 29 proposals rece 97 renewals were made during the year 2004-05. In t total a of out scientists superannuated outstanding recommended during 2004-2005 are as given below: given as are 2004-2005 during recommended n i The etc. IIT’s Scientists Institutes/ Academic Professors/ Universities/ to grants research of form m and engineering agriculture, including Technology resea promote toassistance financial CSIRprovides PROGRAMS SUPPORT SPECIAL AND SCHEMES RESEARCH MURAL EXTRA below: given as are 2005 those countries. The returning from foreign selecti employment en regular in not are who scientists, personnel medical Indian qualified highly to placement The Senior Research Associateship (SRA) is primaril (SRA) ASSOCIATESHIP RESEARCH SENIOR 2004-2005 563 159 549 543 511 159 179 223 ass Scheme, Scientistsfinancial the Emeritus Under 563 576 2004-2005 555 2003-2004 166 2002-2003 206 202 71 88 Total No. 93 95 82 of SRA No. 2004-2005 134 No of SRA 2003-2004 2002-2003 Year erTtlN.o eomne Renewals Recommended Total No. of Year Proposals eetd Jie Supported Joined Selected 162 ons made during the ons during made 2004-year he Sponsored Scheme category, of 130 proposals received and received proposals 130 of y y meant to provide temporary rch in the field of Science and Science of field the in rch ived ived and 37 ongoing schemes me o rsac schemes research of umber ier, ehooit, and technologists, gineers, rglr mlyet in employment regular n istance was provided 24to provided was istance t of 14 proposals receivedproposals 14 of t dcn. t s ie i the in given is It edicine. in the country, includingcountry, the in Celebrations of CSIR on 26on CSIR of Celebrations the on Technology and Science for Minister Hon’ble Sch Award Interns Research Jubilee Diamond CSIR The SCHEMEAWARD INTERNS RESEARCH JUBILEE CSIR DIAMOND NEW HRD INITIATIVES: appreci and participation of terms in both response the reports received from the coordinators of these ope two had organized Most CSIRlaboratories of the (CPYLS) IN SCIENCE LEADERSHIP YOUTH ON CSIR PROGRAM these organizing for cases468 recommended and etc. confer international / national organizing for etc. sc proposals from 532 same committeeconsidered The which outof applications 678 of total a considered abroad held Conferences International the at papers researche young to CSIR by provided is grant Travel GRANTS CONFERENCE / TRAVEL scholars participated in the second training progra training second the in participated scholars ex long month the in participated scholars research for their organizations and theorganizations and their for nation. buoyant world of business and industry and thus bec scientific their of linkages make can they that so The objective of this program is to broad base the SCHOLARS RESEARCH TO SUPPORT ENTREPRENEURSHIP diff in joined scheme.the of inception have candidates 296 of total A 2004. The CSIR. in scientists experienced of supervision which young interns be shall trained in the tools a The The first training program was organized (as a pilo th September 2002. It is a preparative scheme through scheme preparative a is It 2002. September 163 perspective of the research scholars nd nd techniques of research under ence/ symposium/ workshops,symposium/ence/ and technical knowledge to theto knowledge technical and programmes show a very good 380 cases were recommended. were cases 380 mme. scheme has taken off in 2003- in off taken has scheme ation of the scheme.the of ation ome effective wealth creators . The travel grant committee grant travel The . occasion of Diamond Jubilee Diamond ofoccasion rn lbrtre sne the since laboratories erent n days programme. Someof programme. days n events. rie Aon 5 research 50 Around ercise. t exercise) at NCL. About 19 ientific societies/ institutes societies/ ientific s o peetn research presenting for rs eme was announced by announced was eme
Hqrs Activities CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Hqrs Activities the laboratories.the mee for responsible be shall Groups the level; CSIR development resource human the at looking be shall CSIR the all in (HRGs) Groups Resource Human of up annual performance appraisal system for the scienti the for system appraisal performance annual also undertook in training programmes each laborato C programmes the for accrual system, based accounting system accounting for commercial of introduction projec and scientists senior for management project launche has Centre The deliverables. identified and proje multi-agency and laboratory, inter- are which launc has Plan Year Five CSIR Tenth the in system. emerging specialized needs develo e.g. project for management conducted were programmes training few A a organized programmes of number training diffe for With development. organizational and own their for a to them enable discover and also roles functional and skills their sharpen acquire/ to employees the ou carried were activities Training employees. CSIR the The Headquarters. focus of the activities was o provided by this Unit. this by provided published were 10) (about stories features/ several ear to them of all to ensured res was support logistics their in science covering persons press key the . NT O SINE ISMNTO (USD) DISSEMINATION SCIENCE FOR UNIT 3.7 interfacedIt development. (HRDC)HRDC during the CENTRE year carried out DEVELOPMENT significant activi RESOURCE HUMAN 3.6 other large number of activities.of number large other overall objective through `Team USD’. Besides, this activitie several image-building the period, During USD for p is responsible fully furthering favorable One of the initiatives taken by the Centre during t during Centre the by taken initiatives the of One Effective Effective media relations helped in furthering resu I I interacted with its stakeholders, the laboratories laboratories the stakeholders, its with interacted 164 ties in the area of human resource n training & development of the ublic ublic image of CSIR as a whole. n their confidence in this Unit; this in confidence their n nd exploit their inner potential inner their nd exploit Unit is the hub center for some s were executed tothe achieve executed were s hed large networked projects, networked large hed sts. ting the specific HR needs of needs HR specific the ting finance personnel. The Centre t leaders. Similarly, with the with Similarly, leaders. t and accrual based accounting cts with fixed time schedule time fixed with cts etv diis Appropriate dailies. pective capabilities to perform their perform to capabilities ih h spot f inputs of support the with ry for familiarization of for ry newfamiliarization rent rent categories of CSIR staff. helpingon emphasis with t lt-oriented lt-oriented relationship with he year has been for setting for been has year he tann porme on programmes training d these objectives, the Centrethe objectives, these sus etal a global at centrally issues nr ognzd training organized entre laboratories. The HRDC The laboratories. ig aaiiis n the in capabilities ping and Congress 2005; 2 during its Phase I.Phase its during aesthetically for effective dissemination to were the presentation vi audio-visual and models including DST. onorganized by Wheels being – Exhibition Rail atUnit The the coordinated, the dis central level, CSIR PARTICIPATION IN RAIL VIGYAN EXHIBITION 2005. Technovation 2005; Expo . ERIMN N ASSMN BAD (RAB) BOARD ASSESSMENT AND RECRUITMENT 3.8 Business Summit; Uttaranchal International Trade Fa Trade International Uttaranchal Summit; Business h Gvrmn Sco priiain; ulig Inno 2 2004; Expo Building TRANSMAT participation); Sector Government the Infra R&D 2004, Infra Education-2004; Bangalore Bio & Conference `INDIACHEM 2004’; International Health for Technology Innovation); PharmaceuticalsNew ExpoITPO, Fair, 20 Trade International India Pavilion, the in pavilion CSIR organized Unit The other. the participati the with coordination extensive through to contribution overall CSIR of picture integrated to made were efforts and consolidated was activity developme business its supporting and achievements, a Creating objectives: main two with events relayed Compliance to Quality Parameters by RRL (Jammu). RRL by Parameters Quality to Compliance Her on Programme Training IMT, by Package” Software CSIR63rd the celebrations, Foundation Day release drug molecule under NMITLI Programme, CSIR Diamond Bhatnagar Awards including Function, announcement o rs cvrg ws ucsfly raie drn im during organized successfully was coverage Press CSIR participated in the various national/ internat national/ various the in participated CSIR nd Nutraceuticals Summit; Biotech India 2005; CHEMTEC nd Infra Comm India 2004, International Exhibition & Exhibition International 2004, India Comm Infra 165 sitors at 31 stations across the nation play play of CSIR showcase Vigyanin the theme areas of each eventeach of areas theme the 04; 3rd International Exhibition following events: Technology events: following ng CSIR labs on one side and side one on labs CSIR ng of “Vaxipred of – a“Vaxipred Commercial -2004 -2004 (won First Prize among project, as far as possible, an possible, as far as project, wareness about CSIR and its and CSIR about wareness Delhi (won First Gold Prize Gold First (won Delhi A large number of number displays,A large ir 2004; 92 2004; ir ional exhibitions and other and exhibitions ional care and Herbal Expo 2004; fabricated and displayed and fabricated t fot.Ti important This efforts. nt aie hra n India; in Pharma vative f f the discovery of Anti TB Jubilee Awards function, a Du Idsr for Industry Drug bal otn CI events, CSIR portant nd Indian Science Indian H H World
Hqrs Activities CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Hqrs Activities 166
30 23 8 7 7 pi, 2004 April, 11 2004May, 6 th th th th th th rd –7 April – 7 April th th May 31 st had taken CFTRI technology during year.the during CFTRI technology had taken who licensees to mementoes the presented Mysore, CFTRI: VC, Prof. Shashidhara J. Prasad, University of Society.” the Welfar the for Knowledge Traditional “Importanceof on lecture a delivered Kolkata Manch, Vigyan CFRI: Prof. PaschimSankar Chakraborty, President, Day Technology National celebrated constituentCSIRlaboratories and Management” organized atwas IGIB. Diagnosis Allergy: “Respiratory on Workshop organised. also was Seminar onInformation - "Digital Trends"Emerging Information Resource Center at NCL to A the Nation. Dr. DG-CSIR R.A. Mashelkar, Digitaldedicated celebrated. Day Foundation NEERI celebrated. IGIB of Day Reminiscence safety.Road on lecture & gave Transportation Planning, Engineering Traffic Accidents’. Dr. Traffic T.S. Reddy, Area Coordinato Road ‘Menace of of canvas broad gave a Director, Sikd P. K. Prof. Day. Health World CRRIcelebrated (CPYLS) atwas CSIO.organized Science in Leadership Youth onfor CSIR Programme 169 aeie CSIR CSIR Dateline Dateline aeie CSIR CSIR Dateline Dateline r, of ar, a e
Dateline CSIR CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Dateline CSIR JAMIPOL, Jamshedpur delivered the Technology Day Technology the delivered Jamshedpur JAMIPOL, IIP: Dr. IIP: Dr. Former S. DG,CSIR th Vardarajan, delivered Practice’. Clinical ‘Good on lecture delivered Chair in AIIMS, Clinical Pharmacology, New Delhi Dr. D. RRL-Jammu: S. Seth, National ICM Professor, lecture. NML: Mr. Suresh Thawani, Managing Director, technologies”. sensitive socially seminar NISTADS: was organized on “Towards collaborations. future for Delhi New Ltd. Private Consulting M/s with N.H. was signed MoU also R&D destination”. preferr a as Emerging “India on lecture a delivered Emeritus CSIR Scientist, H.R. Bhojwani, Dr. NEERI: participated.etc Industries, of Associatio Indian Kanpur, Institute, Technology and CSALucknow Management AgricultureAssociation, Lupi Services, Consultancy Tata like, organizations various from representatives which in organized, alsomeet was Entrepreneurs Warfare”. Marketing the Winning Success: Business to Innovation “Fromon lecture a delivered Lucknow Management, Das Prof. of J.K. the NBRI: Institute Indian of Kangra at Dharamshala was the guest.Chief D.C. Technology Day lecture and Shrikant Baldi, Dr. the delivered Johl S.S. Bhushan Padma Prof. IHBT: launched. Project) was Industry Partnership Core Share Facility at IGIB (A Government-Instituti IGIB: The Centre for Genomic Application (TCGA) CSIO by observed day Open lecture da the Technology delivered Singh D.B. Prof. CMERI: varieties. technologies/plant the CIMAP’s and adopting exploiting for rewarded were farmers The bi-products. and technologies processing their and plants aromatic and medicinal in development recent on knowledge gathering for theof scientistsCIM with interacted institute and the studentsvisited hundred five Around CIMAP: 170 AP on- ed n, e R n y June, 2004June, 10 8 5 31 29 25 20 15 12 4 th th th th th th st th th th -26 –21 May 4- th st th June Five days visit of Mr. G. M. Sadyalunda, Syste Sadyalunda, G. M. Mr. of days visit Five June in programme.in the participate actively members team Sixty Beach,Goa. Candolimat Ocean Day World of a part as programme of (MCSI) India conducted marine awareness ConservationSociety Marine association with in NIO species. endangered and wildlife conservationof of methodology the Ahasan Conservator(Chief of Forest, UP) who outlin Mohd.Mr. the by Environment Day occasionWorld of on delivered was Environment” Our and “Biodiversity on A lecture Day. Environment World ITRCcelebrated NEERI.at celebrated Environment day World First test flight of SARAS aircraft by NAL. INFLIBNET to NISCAIR. Murthy, Two Director, days T.A.V. visit of Dr. Workshop. Hindi Administrative days two organized CEERI Industry Nanocompositesfor Clay Polymer onWorkshop organized NCL Science”. Informal and Formal between Bridges Building Think: GrassrootsInnovators Creative do “How on Lecture Memorial Tilak D. B. Prof. second the delivered FoundationInnovation National Chairperson, Vice Executiveand Ahmedabad IIM, at Entrepreneurship in Chair Lalbhai Gupta, Kasturbhai K. Anil Prof. Day, Technology National Onof occasionthe NCL: industry thein Hydrocarbon Country”. of Doyen “The on Lecture Day Technology Community Participation”.Community Conservationconference‘Rain onWater and one-day a organized jointly Association, Officers’ The UP Water Ground and Day: WaterGround NBRI Organization Organization to NISCAIR. Proper Industrial Regional African Patent Examiner, Sackey, and Administrator Emmanuel Mr. Kofi-Agyir 171 m ty d ed
Dateline CSIR CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Dateline CSIR July, July, 2004 14 26 25 11 8 4 15 1 11 th th st th th th th th th -27 -16 th th IHBT Annual Report 2003-04 onReport occasion.the 2003-04 Annual IHBT in the field of Indian medicine participated. medicine Indian of field the in resea and industrialists technologists, scientists, food 60 About meet. the inaugurated neurobiologist, noted Varma, M. R. Prof. Melkote. Research, of SanskritassociationAcademy CFTRI and with hel was Heritage’ of Years 5000 Food – of Tradition Convention Science andonFirst National `The Therapeutics”. New to Pathway Alternative The – Triangle Golden “The on address keynote the delivered DG-CSIR Mashelkar, R.A. Dr NCL. by Workshop on organised was Health Fusion Technology Alliance Research Global IGIB.visited Development Ocean of Department and Technology Ministry (Independent Charge) of Science & Sibal, of Kapil State Shri Minister Hon’ble Bhawan Handique at Jorhat. at University KantaRadha Pathak, VC, Dibrugarh Kulendu Prof. by inaugurated was 2004 Awareness RRL-Jorhat Year thefor of programme Scientific Japan. Tsukuba NIMS, at Applications Environmental for Materials Advanced on workshop one a day organized jointly Nagpur NEERI, and Japan Tsukuba, The Institute National for Science Material (NIMS) Genome: A of Gift the 20 Humanon `The lecture delivered CCMB Director, Sing Lalji Dr. day. foundation its celebrated IHBT Health Camp at Chinhat, Lucknow. CDRI organized Science Programme-cum-Awareness and Institute of Science of Modern Art Gallary, NEERIMum by organized jointly was Options” Reuse and A workshop on “Innovative Wastewater Treatment Technology and Ocean Development, Hon’ble Finance Hon’ble Development, Ocean and Technology of Minister State Charge) for (Independent Science Hon’b Sibal, Kapil Shri meeting. the over presided Minister and President, CSIR Manmohan Dr. Singh Prim Hon’ble of CSIRheld. theSociety Meetingwas the 21the st. Prof. C.L. Khetrapal, Chief Guestreleased Chief Khetrapal, C.L. Prof. 172 th Century for& Challenges rchers h, bai. & le d in d e 28 31 6 30 29 4 August, 2004 th th st th th th Johnson Space Centre, Houstan, USA visited NISCAIR. Erbium Doped Fiber Amplifier”. Fiber Doped Erbium for suitable chip Laser Pump nm 980 Packaged Scaled Hermetical of “Development on project collaborative the for Hyderabad PhotonicsLtd., Optiwave CGCRI CEERI, between and An was agreement signed Schemeetc. 2004 Award performance outstanding and suggestions CSIRinnovati of formulation 2001; rules, promotion assessment and recruitment scientistsCSIR to amendment bodies/PSUs; autonomous the to scheme pension new of applicability proposals; NMITLI originated industry of processing for procedure existing in modification CSIR; by setupcenters outreachof performance the committeereview to of approval report of Innovationthe (NIF); Fund Nation of creation science; in excellence for Medal Institution of an onAward Ramachandran GoldG.N. CSIO held.was and Vice President, CSIR visited IICT.& CCMBCSIR visited President, and Vice S&T Charge), Oceanand (Independent Development, state of Minister Hon’ble Sibal, Kapil Shri Rig”. Bearing the “Journal Gas inaugurated and Natural IIP: Secretary, of Shri S.C. Min. Triphathi, Petrol 39 signed. was years five of period a for tubes Discharge Gas Vacuumand Devices, Materials, Tuner, Electron in Research (Maharashtra), collaboration regarding for Joint Nanded Vishnupuri, University, Marathawad An MoU Swami CEERI and between Ramanand Teerth celebrated. was CECRIDay Foundation 162 occasion.the graced also Societythe of members distinguished and Minister Prof. Kumar Krishen, Chief Technologist, NASA Chief KumarProf. Technologist, Krishen, th nd Convocation Centre Training of ofIndo-Swiss meeting of GB was held. It approved the It approved held. was GB meeting of 173 eum al ve ly
Dateline CSIR CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Dateline CSIR 25 22 21 19 18 12 8 27 7 th th th th nd st th th th -22 -19 -13 nd th th see the work on “Monsoon Prediction”.“Monsoonon work the see to Lab Flosolver NAL’s visited Development Ocean Charge), (Independent Science & andTechnology State of Minister Hon’ble Sibal, Kapil Shri. Inaugural Flight of SARAS. NAL. at Conference Directors’ held of CSIRLaboratories Patent Office NISCAIR.visited European Elect:, President Brimelow, Alison Ms. Mitigation (CFM-2004) was held at NML. and Failures Corrosion, on seminar National Association.Processors’ Food India All and Corporation Ltd. Industries Small National with collaboration in RRL-Jammu by organized was Industry Processing Food Scale Small in Management Quality Total on Workshop of laboratory.the the activities with apprised was He CCMB. visited Development Ocean Charge) Science for (Independent & andTechnology State of Minister Hon’ble Sibal, Shri Kapil gathering.the CSIRaddressed President Vice and Development Ocean and Technology (Independent of Charge), Ministry Science & State of Minister Hon’ble Sibal, Shri Kapil President Kalam, and of India Abdul A.P.J. Dr. H.E. CLRI, which in and Prasar with Vigyan collaboration in Delhi, New at Vigyan organized Bhawan, wa Science” of Celebration A Helix: Triple Collagen Ramachandran “50 Years of G.N. Prof. Collagen by of Structure Helical Triple of discovery monumental celebrateto symposium day one organized IGIB Techniques) (Opth. B.Sc for conducting programme collaborative for MOU between signed CSIO and GMCH, Chandigarh One day seminar on ‘Amorphous Nanocrystalline‘Amorphous on & day seminar One System”Transportation Chairman, G ISRO Madhavan Nair, on “Future Space Dr. by delivered was NAL lecture of Foundation Day 174 s 8 6 1 6 1 30 28 30 1 2004September, th th st th st st -30 -14 th th -8 -7 th th th th th Administration, Administration, South Africa visited NISCAIR. and Service Public Department of Ngcobo, Mandla M Pretoria Ltd, Pvt. McKaySita Dimakatso Motshabi, CSIR Mabaso, SourceHead, Open Dr.Centre, Vice Mr. Mr. Hamanzu, Nhlanhla Governor, Tokyo, NCL. visited CSIR President, Vice and Development Ocean Science Charge), and (Independent Technology & State of Minister Hon’ble Sibal, Shri Kapil Month Hindi at IIP.organized at was held NBRI. in of Gardens Botanic India” Resource genetic) (plant Biodiversity of Management National workshop onTwo-day “Information organised. were language Hindi on programmes various occasion On this NML. by celebrated was Pakhwara Hindi Jorhat. RRL, at held Region East Nor in Industries onBased Meet Food interactive An Fortnight atHindi celebrated was NAL. 8 Geneva, Switzerland visited NISCAIR. Division, Property Intellectual World Division, Property Intellectual Global Bhatti, Shakeel Mr. NML. held Synthesiswas Characterisation’ Materials: and IMT. CSIO& visited CSIR Vice-President, and Development Oceanand Science & Technology for charge) State of Minister Union (Independ Sibal, Shri Kapil cooperation. and interaction research and academic promote to Vidyapeeth Banasathaliand CEERI between An signed MoU guest. by CDRI. Dr. DG, R.A. CSIRMashelkar, was the chief organized was Discovery’ toPath `The Drug entitled th National Conference on Chemistry & Biology Conference Chemistry & on National 175 ent at th s r.
Dateline CSIR CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Dateline CSIR 26 24 21 10 9 9 8 th th th st th -10 -16 -14 th th th th th persons including students, visited the laboratory. the visited students, including persons 10275 wherein observed was day Open CCMB: were: laboratories the eventsin Someimportant great enthusiasm. with celebrated `CSIR-the entitled of Day renewal’. The challenge Lectured Day Foundation the delivered Mumbai ICICIGanguly, Chairman, OneSource Limited, Technology Award were announced. Dr. A.S. Awards. Bhatnagar and Awards CSIR Diamond Jubilee Technology2004 CSIRCSIR YoungAwards, Scientists the presented Development Ocean and Technology of Minister State Charge) for (Independent Science Hon’bleSibal, Kapil CSIRShri Day: Foundation NISCAIR. USA visited Philadelphia, Department, Thomson ISI, Development Editorial Director, Testa, James Mr. Garden. and Botanic Centre atEco-Education its CDRI, ITRCCIMAP, and NBRI NBRIwas organized by viz, CSIRLabs, based Lucknow the of achievements signific and activities the depicting exhibition An Ramachandran.Prof. achievements scientific of the spoke on Ramachandran studentProf. of former a and Pune of University Vice-Chancellor, Kolaskar, A.S Prof. collagen. protein fibrous of elucidation structu of onyears occasion 50Ramachandran the of G.N. Prof. contributions of scientific pioneering Chemical Research Society (CRS) of Indian and India withassociation in NCL Helix. Triple Collagen 50 years Ramachandran: of G.N. Remembering NBRI.at held was benefits” societal their and bioagents fungal in advances “Recent on Symposium conducted at was NML. Harvesting’ and Purification onConservation, ‘Water: Hindi in seminar Two day Sopan. magazine Hindi released University Sagar V.C. Former Verma, D. Dr. week. awareness Hindi organized RRL, Bhopal & NCL. CEERI by organized Week Hindi 176 . ant was & re Jagmohan Singh, VC, CSKHPKV, Palampur was the VC,Palampur was CSKHPKV, Jagmohan Singh, modelofscience appropriate forsocietal developme current our “Is on lecture delivered Biotechnology IMT: M.K. Prof. Bhan, Deptt. Secretary, of Fuels”. Future “Creating IIPof Slogan the released also He lecture. Day FoundationCSIR delivered Gas Natural & Petroleum IIP: Mr. S. Secretary, Minist Srinivasan Additional occasion.theon giv also was section weaker of students meritorious toAward IHBT. by was released variety of lavender to Shri of Ravinder Jamwal `Akash’, aKandwari. givenwas Award’ Adoption Chief Guest. `Technology Dr.`Genome Security’. Lecture on Science & Food D the Foundation Chattoo delivered B.B. Prof. IHBT: on Imaging"."Hyper-Spectral lectu a delivered Research, Chandigarh and Training Institute National Teachers’ of Technical Director, Bajpai, O.P. Prof. observed. was day Open CSIO: scientists.with the intera and conservatories school, plant exhibition, the went CIMAPround and visited life of walks all fro people & children school 300 than occasion more onOn human its effect 'alcoholhealth'. the th and theon lecture a delivered guestwho chief the was Luckno Sciences, Medical of Institute Graduate Post CIMAP: Prof. Kartar Singh, Director, Sanjay Gandhi occasion.the on organized competitions several in prizes won had who employees CFTRI of children to distributed were Prizes India”. Rural in Security “Energy on lecture day foundation delivered Bengal West Govt.to Special of theSecretary Power, Department and(WBREA) Agency Energy Renewable Bengal Oscar (UK) for Award the year WestDirector, 2003, CFRI: Shri S. P. Gun Chowdhury, winner of Green More toHeart Diseases?’ Prone are CoronaryIndians `Why entitled Lecture Day Foundation the delivered CDRI: Prof. K.K. Director, Talwar, PGIMS, Chandigar 177 e ry ry of cted nt?”. of en w m ay re h
Dateline CSIR CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Dateline CSIR 28 th RRL- Thiruvanathapuram Open day observed day Open Thiruvanathapuram RRL- respectively. Mohali Research, & Education InstitutePharmaceut of National Director, Ramarao, P. Prof. and Kolkata Science, of Cultivationthe Association fo Manju Indian Prof. Ray, to conferred 20032002 wereand thefor years Awards Memorial C. Chopra I. Dr. discovery”. receptors in drug coupled Protein “G on lecture delivered Mohali Research,& Education Pharmaceutical ofInstitute NationalDirector, Ramarao, P. Prof. RRL-Jammu: Released. Technology Rural of Journal RRL-Bhopal: held. competition Essay observed, was day Open NML: observed. also was Open D India’. in of Biotechnology `Growth entitled lecture a delivered Bangalore Science, of Institute NIO: Prof. G. Padmanaban, Director Indian(Retd.), audience.the was SARASto shown on video film Onthis a occasion Development. Self & Values Attitudes Effectiveness Human of Technology & “Science on lecture delivered Prof. Raju, DelhiFormer Director V.S. IIT, NEERI: Biodiversity”. India’s through JourneyChemist’s “A lecture delivered Delhi of University research, Biomedical Centre for Ambedkar B.R. Dr. Professor, Visiting presently and NCL of scienti distinguished former a Dev, Sukh Prof. NCL: NAL. visitedForests and Environment and Technology and onCommitteeStanding Science The Parliamentary Applications” and Diagnostics Flow “Advanced o Lecture Business a delivered Vishwanath R. P. Dr. Experience” andIssues Development- Technology “Rural DeptN. Dr. Raghunandan, B. of Aerospace, onIISc. by delivered was lecture CSIR Day Foundation NAL: Commissioner, inaugurated “Prakruthi; Fruits and Fruits “Prakruthi; inaugurated Commissioner, Canadian High Hon’ble Ms. Edwards, Lucie 178 r ical ay st n 14 8 20 15 13 4 6 30 2 October, 2004 th th th nd th th th th th -8 -10 -15 Sept. - 1 - Sept. th th th st October Two days International Policy Workshop on ` onWorkshop Policy International days Two October by by IGIB. (SIOS) were (SIOS) thewere of this organizers workshop. RattanSociety and Ocean (INBAR) for Indian Studies along for with International Network andBamboo (CIBART) Technology Resourceand Bamboo Indian Centre forThe conducted was NIO. at in Fisheries’ (Zonal) held at CBRI. held (Zonal) compounds. novel of processing and analysis chemical (TKDL), Library Digital Knowledge (RS & GIS), Traditional System Information Geographic and Remote Sensing facilities has Unit The function. the over presided alsoCommission Planning Member Chopra, V.L. Prof. Museum. and Unit Development Bioresource M. Dr. IHBT: K. inaugurated Secretary, thBhan, DBT Switzerland visited NISCAIR. Geneva, Division, Property Intellectual World Director Deputy Rai, Pushpendra and CentreMr. Economic Development DDG, Geoffrey, Mr. Y.U. 2 Biotech 2004, Information Facilitation (TIF) programme with DSIR. Technologyonmeet brainstorming a conducted CCMB 37 Day. Foundation its celebrated Thiruvanathapuram RRL, CEERI. byorganized Programme Training Translation Hindi Karnataka.of region Hills BR of the among tribal entreprene promoteto objective an with Initiatives Local Fund for theCanadian supportwith of upset Centre The Taluk. Yelandur Mole, Uppina at CFTRI of Centre,” Training and Processing Vegetable contribution was distributed. was contribution Chief Guest. Awards best for andperformance was of thVC,Mysore University Prasad, Shashidhara J. Prof. day. foundation its celebrated CFTRI th Shanti Swarup Memorial Bhatnagar Tournament 179 nd National Conference was organizedwas Conference National Bamboo for urs e e
Dateline CSIR CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Dateline CSIR 2 1 30 29 29 29 28 26 1 November, 2004 1 27 nd st st st -6 -5 3– th th th th th th th -6 -30 -29 -29 –29 th th th rd th th th th Jorhat occasion. theon staff the addressed Mysore, Railway, Western South CFTRI. Usha Mrs. Manager, Mathur, Divisional by observed was Week Awareness Vigilance National NML and NEERI. at observed was Week Awareness Vigilance National RRL,at observed Week Awareness Vigilance National organized. were contest debate and writ essay eventslike the members, staff the among awarenesscrate to week vigilance observed NCL ITRC. by organized roadmap and their sector unorganized in problems health Occupational Processing’. Signal in ‘Perspectives on Delhi Deputy Director, Prasad, Surendra lecture Prof. by a organising by was celebrated Day CSIO Foundation at was IMT.organized Science in Leadership Youth onfor CSIR Programme organized at CIMAP. The second Interactive Meet National was (NIM-2004) superannuation. his of eve the on Division Chemistry and Catalysis Inorganic head, Sivasanker, Subramanian honourin Catalysis Dr. Research” of in Trends “RecentonSymposium organized NCL Club. Flying toKarnal Hansa HNX VT from was (of BangaloreNAL) ferried CPYLS at NIO. attended region Goa of students topranking Eighty CEERI. by organized was students meritorious CPYLS-2004 – Scientific forProgramme Awareness eve sports seven for participated Laboratories CSIR DG-CSIR. A total of 272 from participants 10 diffe Mashelkar, R.A. tournament Dr. by inaugurated was The at was held NEERI. Tournament (Zonal) XXXVII Shanti MemorialBhatnagar Swarup 180 rent IIT nts. ing 16 27 25 24 18 8 6 4 2 26 nd th th th th th th th th th -10 -6 -19 -25 th th th th Junior NOST Symposium. The first Junior-Nationalfirst Symposium. The Junior NOST participated in the J-NOST symposium. J-NOST the in participated and IISc, R&D Universities, Centres of industry, CSIRlaboratories, including laboratories research lea in chemistry organic in research their pursuing More at NCL. organized than students, who fifty are was symposium (J-NOST) Trust Symposium Organic biologists- on “Discovery” at IMT.at “Discovery” on biologists- a amongdoyen Bachhawat, Indian B.K. late Prof. theof memory in Oration Annual lecture- memorial Bachhawat delivered Bangalore Organization, Researc Space Indian the of Professor Distinguished Prof. Menon, M.G.K. FRS, SarabhaiVikram Dr. lecture. day foundation the delivered UK London, of College University of Wolpert Lewis Prof. day. foundation its celebrated CCMB 54its celebrated NML teachers. parents/guardians/ their oneof CPYLSwith along participated Haveli Nagar CBSE and Union of Territory Diu, Daman Dadra and CSMCRI: 94 outstanding students from ICSE,GSEB, Jorhat.RRL by organized was production Silk Improveto Biotechnology and Biology Molecular Biochemistry, Silkworm assama) The National First onSeminar Muga (Antheraea ITRC. by organized Cosmetics Assessmentof Safety on Symposium National CEERI by was organized Delhi New DRDO, (ARMREB), Research of ArmamentBoard Awareness Workshop Dutt Hon’ble Tiwari, Chief Uttranchal.Minister, Two test by off cars of Naray IIP Shri flagged were celebrated. was Day ITRCFoundation parameters” tocompliance quality for Industry Drug “Herbal Cours Training Regional a organized Italy Trieste, RRL, Jammu collaboration in with ICS- UNIDO, 181 th Foundation Day. Foundation IITs, an ding e on e h
Dateline CSIR CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Dateline CSIR 13 15 14 13 7 6 4 30 2 December, 2004 30 th th th nd -7 -5 th th th th th th -9 -3 -15 th th th rd th Joint Workshop on “Biodiversity Informatics: An IndInformatics: Joint Workshop on “Biodiversity facilities in the 9 the in facilities R&D and equipments of Modernization of ratification and review Bangalore; NAL, at by NWTC building construction of aircraft hangar (SARAS) and associa for proposal development; business for consultants of engagement for scheme instts.; labs/ national of Heads to powers of abroad-devolution scientists of deputation projects; scheme NMITLI for repayment lo of utilization completion; for scheduled project of NMITLIsanctioning for review loan; directive scheme-policy NMITLI under industry to support Ocean Engineering was held at NIO. at held was OceanEngineering National Conference Third Indian on andHarbour US Initiative” held was at NCL. 163 Structures (PCSS at held was 04) the NML. Stee Corrosion of in Prevention onSeminar National Conference.thein participated institute and universities different from delegates 150About Seas’. Tropical the of `Microbiology on Conference days a three NIO organized CampHealth atLucknow. Itaunja, CDRI organized Science Programme-cum-Awareness (CPYLS) atwas CSIO.organized Science in Leadership Youth onfor CSIR Programme ChrysanthemumColeus Annual show. and i.e. year, the event of colourful and bright a organized NBRI NCL.at CPYLSorganized Programme Chairman, HAL Mohanty N.R. to over Mr. Handed of ProductionTejas Series Limited first of Parts CompositeAirframe 2004. December ISOrequirements 9000:2000 w.e.f. p asyears another for the three of licence renewal the recommended and Institutethe of audit renewal out the carried Standards of CRRI:Indian Bureau rd meeting of GB was held. It approved financial approved It was held. GB of meeting 182 th Five Year Plan etc. Plan Year Five er er IS/ s an ted l o- , 27 18 17 15 15 13 30 27 21 20 19 15 3 rd th st th th th th th th th th th th –5 -22 -18 -15 -28 -20 -31 -31 - 21 th nd th th th st st th st January, January, 2005 Catalysis. attended the programmethe attended outstanding students from JharkhandBihar and thirty-seven wherein Science, in Leadership CSIRon Youthforprogramme organized NML show. Gladiolus and Rose Annual the organized NBRI Shri N.D. Tiwari, Chief Minister (Uttranchal) by inaugurated Gas ConservationForthnight & Oil compounds. malarial of new twoanti- commercialization Mumbai for Sciences, Shreya Life with an NIO agreement signed at was held ITRC.(GLP) Practice Laboratory of Good Conference National smell in the fruifly, of“Sense on lecture Day Foundation NCL delivered Bangalore Sciences, Biological for Center National TIF Director, FRS, former Siddiqi, Obaid Prof. NCL: Plants”.Removal Iron and Arsenic based Membrane Ceramic Demonstration Reactors of Membrane and CGCRI: Workshop International on “Membranes and NEERI.at held CPYLS participated students 13 CPYLSRRL-Triv.at attendED students 58 – website consortiu Libraries Special Lucknow of Inauguration participated. havestudents 89 wherein Science in Leadership Youthonfor CSIRprogramme organized Jammu RRL, NISCAIR.Slovania visited Ljubljana, ICPE, Mutreja,K. V. Mr. DG and Lukman, Benjamin Prof. NCL.at organized in Materials workshop onIndo-US and Networkingcollaborations company BioMantra. with bioinformatics collaboration in IMTECH by launched was ‘VaxiPred’ called design vaccine for suited tool software A CSMCRI organized 17 CSMCRIorganized www.lucklibnet 183 Drosophila melanogaster th National onSymposium National .com at CDRI.was done ”. R m
Dateline CSIR CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Dateline CSIR 28 17 17 22 10 9 31 30 24 19 3 2005February, th rd th th th nd th th th -13 st th -20 -12 -31 -21 th th th st st jointly on utilization of solid industrial wastes. industrial solid of utilization on jointly NCL. held (MRSI) was Society Materials Researchof India Tournament (Indoor & Outdoor Finals) at ITRC. & Outdoor Tournament Finals) (Indoor XXXVII Shanti MemorialBhatnagar Swarup 54its Celebrated CDRI and the 16 Industry”Automotive for “Materials on Symposium AERO INDIA 2005. NAL’s HANSA and SARAS aircrafts participated in fields. allied and Electrochemistry of fie the in R&D of benefits mutual the for Karaikudi University,an Alagappa MOU CECRI with signed marketing. and measures control quality besides MAPs of technologies varieties, latest the of apprised were participants The the fair. in other participated statesand entrepreneurs from parts different of UP, Uttaranch and farmers of Thousands organized. was Mela Kisan entrepreneurs in a big way “Harit-CIM-Utsav” with As a continuing effort of CIMAP to reach an farmers NEERI.at CPYLS in participated region Vidarbha and studentsNagpur 13 from for Astronomy and Astrophysics Pune.(IUCAA), Emeritus Cent Inter-University Professor, Narlikar, V. Jayant Prof. by delivered was Illusions’ `Cosmic entitl lecture A day. foundation its celebrated NIO 22 its celebrated IMTECH results. and ideas of exchange for forum provided and centers Oceanspreading Indian theat processes biological and chemical physical, geophysical, geological, the on focused workshop System atwas The (TOP-AIRs)’ NIO. organized Ridge Ocean Indian the along Processes Oceanic `Tectonic entitled Workshop Ridge Inter days Three Chemical Technology, Russia & RRL-Bhopal to workto RRL-Bhopal & Russia Technology, Chemical Institute Chemistry between A&signed of MoU th Annual Meeting General of(AGM) 184 th Foundation Day. Foundation nd Foundation Day. Foundation ed re ld al d at & 18 16 28 28 26 8 March, 2005 th th th th th th -17 -28 th th CIMAP celebrated its Foundation Day.Foundation its celebrated CIMAP 44its celebrated Jorhat RRL, RRL-Jorhat.at Technology Science & Recent & onSeminar National Awareness Advances in organized at NCL. Technology and Nanoscience on Conference National BhopalRRL, at observed Day Science National Antioxidants. and Dietary onthe Radicals the NSD ‘Free topic deliver Biology Radiation and Genetics of Professor National Science Day, G.J. Dr. Sharma, RRL, Jorhat, Chemical Factory”. Incredible An Brain: “Human lecture on special a delivered Delhi New Society, Centre Research Brain National P. President, N. Prof. Tandon, NCL: the of era Technology”.Information inDiscovery and Design “Joys ofon Drug Hyderabad Ltd.Reddy’s Iqbal Dr. Laboratories FASc, FNA. Javed Dr. by lecture was delivered Science Day NAL: Quietness”. for “Designing on lecture day Science delivered Bangalore IISc., Munjal, CSIO: M.L. Prof. polysachhasides”. unmodified and modified fro materials Technology “High on lecture delivered CIMAP: R.P. Prof. UniversityVC, Singh, Lucknow National Science Day. CFRI. at organized (HRCOKE 2005) Ovens’Coke Recovery ‘Heat on workshop National 185 th Foundation Day.Foundation the ed m
Dateline CSIR CSIR Annual Report 2004-05
OA 1 7 0 7 44 272 500 175 418 TOTAL SERC RRL(T) RRL(JT) RRL(J) RRL(BP) RRL(BHU) NPL NML NIO NGRI NEERI NCL NBRI NAL ITRC IMT IIP IICT IICB IHBT IGIB CSMCRI CSIR(SCH) CSIO CRRI CMRI CMERI CLRI CIMAP CGCRI CFTRI CFRI CEERI CECRI CDRI CCMB CBRI IE RNE IE RNE COPYRIGHTS GRANTED FILED GRANTED FILED INTELLECTUAL PROPERTY FROM CSIR DURING 2004-05 DURING CSIR FROM PROPERTY INTELLECTUAL
41 48 44 13 32 4 1 21 16 7 44 32 14 3 48 4 17 7 35 13 0 39 7 14 4 1 28 21 0 61 48 23 15 15 12 0 28 3 0 3 4 19 26 1 0 2 29 10 12 6 15 0 44 19 14 5 11 13 1 29 18 31 18 0 12 15 59 10 21 31 0 1 13 1 1 1 0 1 0 1 7 6 0 5 1 1 11 2 2 0 0 2 10 4 12 1 0 1 0 1 0 1 2 9 2 11 9 3 1 9 0 3 0 0 5 1 3 144 7 6 1 2 0 0 2 2 7 0 4 1 9 0 2 3 7 6 4 19 0 4 0 2 6 0 0 0 3 1 2 0 1 1 8 0 0 4 1 0 2 0 INDIA INDIA 189 FOREIGN NEUE- I- ANNEXURE FILED
Annexures CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Annexures ahfe htahraKl akr2001260589 Bhattacharya Kali Sankar 6838525 6737037 NS, Raghavan M Sinha Paras Nath, Ariyanan Thiagarajan Mani, ash fuel Process for the production of low Pitchumani S, Doll CFRI conductive polymer gel Ramasamy Chandrasek Process for manufacture of proton lithium cobaltate Solid state thermal synthesis of CECRI Puri Sunil Kum Singh Chandan, the preparation thereof antimalarial agents and a process for Substituted 1,2,4-trioxanes useful as Puri Sunil Kum Singh Chandan, the preparation thereof Singh Chandan, antimalarial Puri agents S and a process for Substituted 1,2,4-trioxanes useful as producing the substituted 1,2,4-trioxanes Singh Chandan, antimalarial Puri agents S and a process of Substituted 1,2,4-trioxanes as producing the substituted 1,2,4-trioxanes antimalarial agents and a process of Substituted 1,2,4-trioxanes as podppie hraetclDwivedi Anil Kumar, Rag Srivastava Sudh compositions Khanna Madhu, andHa method of treatment opioid peptide, pharmaceutical Inclusion completes of a high potent gn Srivastava Pratima, Pandey Vikash Kumar,; Dutta Guru Pra Anil Kumar, Singh agent Thapliyal Harsh Pa Pratap Ram, Bhaduri 1-4-pentane diamine as gametocidel - n'-(6-methyl-8- quinodinyl0 ethylidinotetra hydrofuran -2-one) Use of primaquine derivative n'- CDRI against plant pathogens Geol AL, Lakshmi for developing novel bactericides Verma Sunil Kumar Shikimate dehydrogenase as a garget identity of animal parts and products Universal primers to establish the CCMB FOREIGN PATENTS GRANTED TO GRANTED PATENTS FOREIGN CSIR DURING 2004-05 Vasudevan, Ramaiyer Gangadharan Prasad, Srivastava, Jagdish Sri Ramchandra, Asthana, Onkar Shio Kuma Chandra, Srivastava Sudhir, Singh 190 r2003/2453 6737438 ar ar ir, Murthy, Puvvada Twr ali ZA Tiwari Pallvi, US Tiwari Pallvi, R, Sonti RV US 6869601 US R, Sonti RV egpaPrh,AU Sengupta Partha, ,Rnawm US i H, Rengaswamy Satyawan, ti, Puri Sunil 1055427 B1 1055427 Puri ti, Sunil ig aj ZA , Singh Lalji aau,US q Wahajul, AiaPaa,EP Amiya Prasad, nlKmrVI unil Kumar SI unil Kumar rn US aran, sad, Dwivedi ui a,6740639 hubir Ram, NEUE I - ANNEXURE 4230 84585 2003/7489 A rprn h aeKltorn os aaae 680589 Kulathooran, Borse Babasaheb preparing the same Raghavan Bash Sugarcane juice spread and a process for sporotrichum species Divakar Divakar Soundar, Karanth Nayaka Avinash Prahalad, Dumm Divakar S, Karanth NG, Sh sporotrichum species Shivanandappa Th and its Bhaskarraoisolation from Ramesh,fungus Mysore Compound Satturas cholinesterase AP, inhibitor Rao KC, aldose reductase inhibitor A process for the preparation of an Kulathooran, Borse Baba Raghavan Bashyam, Ra for preparing the same beveragepowder and a process Ready-to-dilute sugarcane juice preparation Punaroor, Prak of the Swamilingappafood B composition food composition and a process for the A high protein nutritive cereal based fpoenhdoyaefo eue Harendranath R, G of protein hydrolysate from legumes Prakash V, A An improved process for the Murthy preparation Kowsalya Shankar Swamylingappa Bhag hydrolysate from milk protein Process for preparation of protein- lryVraS,SnhG audrS1372874 Verma SK, Singh G, Mazumdar S 528519 Swapan Kumar; Basu Sibendra Harendranath R, G of protein hydrolysate from legumes Prakash V, A An improved process for the preparation Radha C, Kumar protein hydrolysate 6734309 Process for the preparation of a high CFTRI Rao SK, Ghosh Lakshmi Narayan, Singh Baldev, slurry Process for the production of fly ash Rao Sukuru Ram slurry Process for the production of fly ash acid hydrazide rcs o h ytei fioioii Ray Subhas Process for the synthesis of isonicotinic Katte Katte Ganesh waraiah, Sulochanamma Guruguntla Nagarajarao, Prakash Vishwesh- Bhaskarrao, Ramesh Mysore Vishweshwaraiah Nagarajarao, Prakash Shamanathaka Sastry MC, Joseph J. Radha C, Singh SA, Subba Rao BH, Tirumakudalu Chikkaraja Sindhu Cheluvaraya Shamanthaka, Kanya Vishweshwariah, Sastry Mysore Shamanathaka Sastry MC, Joseph J. Radha C, Singh SA, Subba Rao BH, Kumar; Mall Baru Dutta Pashupati, Roy Shyam Kishore Sarkar Prodyot Kumar, Prasad Hiralal, Maharaj Sumant, 191 hnr;NniUS h Nandi Chandra; p a G LK ppu Rao AG, p a G LK ppu Rao AG, K auS,Ml K EP SK, Basu SK, Mall BK, s ihehaihCN1177539C ash Vishweshwariah a,Rmlkhi US yam, Ramalakshmi, kiha hs NZ akrishna; Ghosh R rks NZ PR, Prakash V ay,RoHrdsCNhagya, Rao Haridas Bb N US Babu KN, map,Stu US immappa, Sattur vnrjG 13161 ovindraj G, vnrjG 13159 ovindraj G, ya, Joseph Johny, LK aasm US malakshmi ae 6783785 saheb hre,6759552 y Shereen, ml R6822003 amala TR ,Paah13160 a, Prakash na 528518 5
Annexures CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Annexures pia ie K agpaK alM 2003/5990 SK, Dasgupta K, Paul MC 6751990 Bhadra Shyamal Kumar, Dasgupta 685128 Naskar Milan Kanti, Pal Mrinmay, Bandyopadhyay T, optical fiber Process for making rare earth doped Bandyopadhyay Tar Bhashyam Mandayam K, Srinivas optical fiber Process for making rare earth doped Sen Ranjan, Mis optical fibre 6863828 A process of making rare earth doped CGCRI pearl millet Meera Manchanah Narasimha Ham stable improved flour from sorghum and A process for the production of shelf of protein hydrolysate from legumes 6849453 Haridas A, M An improved process for the preparation Raghavarao Thimmaraju, Narayan Mandayam flavourent Kambadoor N of 2-acetyl-1-pyrroline, the basmati rice Srinivas Pul An improved process for the preparation Thirumakudalu, C 6810794 and a process for preparing Gangadharan Sankaram theThadathil same Singh, Sridevi A high energy high protein food product Naveen Nagaraj polyethylene glycol Process for separation and recovery of Bhagyalakshmi Neel pandanus A medium for clonal propagation of using flue gas Kestur Venka A continous vibro fluidized bed roaster Radha C, Kumar protein hydrolysate Process for the preparation of a high odadapoutteefRnaayBb,Rms 686 Ramalakshmi K, Rangasamy Baby, Ramesh Singh I, Ramesh shelf stable sugarcane juice beverage Process for preparing ready-to-drink food and a product thereof rcs o ihpoencae eelBhattachary A process for high protein coated cereal Jayaprakashan, Jayaprakashan, Raju Ezhil Murugan Kamal, Kamal, Paul Mukul Chandra Shyamlal Kumar, Da Kamal Paul Mukul Chandra, Bhadra Sathendra Anathachar, Rao Baragi V , Rao Tiku Purnima Ravishankar Gokare Aswathanarayana Singara, Prakash V Appu Rao, Prakash Vishweshwariah Thotadamoole, Gopala Rao; Appu Rao 192 ahta uuutUS labhatla, Gurudutt ued,LtaUS a Suvendu, Latha ehMrh,US tesh Murthy, jma ZA ajumdar S Anpra KnaLK Annapurna, Kanya grjro6723856 agarajarao htejeMnt,US s Chatterjee Minati, htaaS ssUS , Chethana S, Ksms n os B US Mn, Borse BB, Rgaa ,6723367 Raghavan B, auaV 23394 papura V, P rks ZA RP, prakash V ikrj idu 13018 hikkaraja Sindhu, li l ydZ,EG alli, Ali Syed Z., e ,Bar ZA Sen R, Bhadra n e ajn US un, Sen Ranjan, warne, Rudrappa US 2003/6958 2003/7566 6880 1 rdcn h aeKumar Sushil TRS, Shasany AK, Daroka Sushil, the essential Kalraoil contentAlok, in Kaaromatic crops Formulation and method for increasing Khanuja acidSPS, biosynthesisS Anwarinhibitors Mohammed, Cha A method for the screening of mycolic producing the same urease inhibitor and a method Patra Dharof Formulation useful as a nitrification and iaillttayrfrn rptiV1245570 6831100 Nath, Tiwari Shi 1298128 Kumar Dinesh, Shu Krishna Kumar, processKumar for preparation of the same Mosquito repellent composition and Tripathi V Khanuja Suman Pree external UV protection Menthyl benzoate Khanuja ChattopadhyaySPS formulations for divanillyl tetrahydrofuran Process for the production of Darokar (-)Mahendra Lata,Pandurang,3,4- TandonKumar S plant Chattopadhyay silybum SK, Agarw marianumagent silymarin from the seeds of the Process Kaholfor At isolation of a hepatoprotective 10-deacetylbaccatin III Process for the preparation of infections Srivastava the treatment of drug resistant bacterial KhanujaFormulation Suman comprising thymol useful in from dihydroartemisinin Rajendra Singh, Rajendra Saxena Sudha from dihydroartemisinin Jain Dhara Process for the preparation of arteethers o rn itlaeada niitcSushil, Shasa cow urine distillate and an antibiotic Khanuja Suman P Pharmaceutical composition containing CIMAP Awasthi S Prakash, Kumar Sushil Pandurang, Kumar SUAjit Kumar, Darokar MahendraSantha, Ahmad Atique, Shasany, Tiruppadiripuliyur Ranganathan Dharmendra, Kumar Sushil SinhaDhawanSaikia Sunita, Prachi, Ahmed Ateeque, Patra Nirmal Kumar, Santha, Agarwal Krishna Kumar, RanganathanTiruppadiripuliyur As re y Kumar Sushil, Vishwakarma Ram Mansing Sunil BalkrishnaSunilMansing Verma Ramkishore, Agarwal Sweta, Vivek Kumar, Gupta Madan Mohan, Gupta Subhash Chandra, Gupta Sinha Prachi, Awasthi Soumya, Pandurang, Singh Monika, Shankar, Darokar Mahendra 193 hnj ua re ig 6720289 Khanuja Suman Preet Singh lPaah ig ia DE ul Prakash, Singh Kiran Sci hse jtKmr 2245719 Suchi, Shasney Ajit Kumar, n hr ia sa CA ani Dhar, Kiran Usha, hn,BauiGB m Chand, Bhakuni yAi ua,Ay a 1330253 ny Ajit Kumar, Arya Jai ia et,KmrUS tiyar Neetu, Kumar iatv ,KmrUS rivastava S, Kumar de,KmrSsi 10016449 udeep, Kumar Sushil S,Siatv ,EP Sk, Srivastava S, PetSnh RU Preet Singh, ha aslRv L 00801425.6 ZL khia, Bansal Ravi etSnh ua EP reet Singh, Kumar l oedaCN kla Yogendra ig,AawlUS t Singh, Agarwal dKkml 2338454 nd Kukhmal, P 6833249 r MP, lS,EP al SK, su GB2360517 nshu,
Annexures CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Annexures ehdo ramn Shasany Ajit Kumar, Kumar Darokar Mahendra Pandurang, Kumar Shankar, Srivastav method of treatment with lysergol Khanuja as Sumanbio-enhancer and Antibiotic pharmaceutical composition infections Srivastava the treatment of drug resistant bacterial KhanujaFormulation Suman comprising thymol useful in (+) catechin Kulshreshtha Kulshreshtha Manish, Sharma Ram Ranganathan Santha K Jai Shanker, T isolation from moringa oleifera of drugs and nutrients, process of its Khanuja Su Nitrile glycoside useful as a bioenhancer Chattopadhyay Sunil B4 10014670 (+) catechin Banerjee Suchi biologically active phenolic coumpound Shawl Abdul Sami, Bindra Rattan Process for the production of a Misra Hari Om, Pant Vasu Amritesh Chandra a broad spectrum of dermatophytoses Shahi Sushi Anti – fungal formulation active against Kishori, Gupta Ajai variety “sujata” abstract opium poppy (papaver somniferum) Opiumless Sharma Jawah and alkaloid-free non-narcotic santonin Jain Dharam An improved process for the isolation of ytei niio Rajendra Singh, Verma Ramkishor, Gupta Madan Mohan, B synthesis inhibitor Jain Dharam Ch scopolatin useful as nitric oxide Process for the isolation of compound Gurudas, Srivastava chromatographing and crystallizing organic solvent, defatting, macerating dried leaves, percolating with Kumar Sushil phyllanthus amarus, by pulverizing and phyllanthin in Chaudhurihigh yield Prabifrom Extracting pure hepatoprotective agent Kumar Sushil Darokar Mahendra Pandurang, Tiruppadiripuliyur Ranganathan, Saikia Dharmendra, Kumar Sushil SinhaDhawan Sunita,Prachi, Ahmed Ateeque, Patra Nirmal Kumar, Santha, Agarwal Krishna Kumar, Tiruppadiripuliyur Ranganathan Monika, Gupta Subhash Chandra Dharmendra, Kaur Harpreet, Singh Chandra Ram, Rashid Mohd Kumar Sushil Prakash, Mehta Vijay Kumar, Kumar, Kumar Sushil Bajaj Ashok Kumar, Singh Anil Lal, Kumar Sushil Kumar Sushil Tewari Amit, Kahol Atul Prakash, Tandon Sudeep, Gupta Shiv Kumar, 194 Sci hse jtKmr 6824795 Suchi, Shasney Ajit Kumar, a re ig,Ay US man Preet Singh, Arya ua,Sul GB l Kumar, Shukla aeaSdasu DE Saxena , Sudhanshu, rpaiiuiu 6858588 iruppadiripuliyur r,AawlSir,2360516 tra, Agarwal Shipra, US ar Ram, Lal Raj PetSnh US Preet Singh, n,Pn era CN and, Pant Neerja, re ig,Ay a ZA Preet Singh, Arya Jai ua, aciDE r Kumar, Bagchi ats ua,2003/2270 a Santosh Kumar, , Dikshit Anupam, 2360705 B 2360705 , Dikshit Anupam, Paah 6730838 Prakash, ahi 10014674 Rashmi, ua,GB Kumar, umar, Saikiaumar, auiZL00108330.9 hakuni dha, noatehrAi;SnhTrn hnj 6750356 Patra Nirmal Kumar; Kumar Kalra Alok; Singh Santhakumar Tirupadiripul Amit; Singh Tarun; Khanuja self-pollinated cymbopogon artini Vaishnavi, a high yielding Darokar Mahen var. Viridis and their use disinfectants comprising artin spicata Khanuja Suman Pr Composition and process for preparing Bhakuni Rajendr into arteether Single pot conversion of artemisinin oneaMohan, Khanuja Suman Preet Singh Sushil, Shasa 2241457 cow urine distillate and an Tandonantibiotic Sundeep, Gupta Khanuja Suman P Kahol Atul Prakash, Pharmaceutical composition containing monniera bascosides from the herb bacopa Srivastava Suchi, Kumar Preparation of an extract rich in for Kumar,producing theDarokar same Mahendra Khanuja Suman P Anti-microbial composition and method Srivastava Suchi, bacterial infections in Khanuja the Suman treatmentPr of drug resistant Formulation comprising thymol useful ehdo ramn Kumar, Shasany Ajit Kumar, Kumar Jai Shankar, Sriva method of treatment with lysergol Khanuja as Sumanbio-enhancer and Antibiotic pharmaceutical composition Jain Dharam Chand, Darokar Mengi Nareshwar Singh Ved Ram, Tanveer Hasan, Bahadur, Singh Hemendra Pratap, Aggrawal Krishna Kumar Ranganathan, Shasany Ajit Kumar, Sweta, Mansing Sunil Balkrishna Mohan, Verma Ramkishore, Agarwal Vivek Kumar, Gupta Madan Gupta Subhash Chandra, Gupta Sinha Prachi, Awasthi Soumya, Pandurang, Singh Monika, Shankar, Darokar Mahendra Suman PS Dharmendra, Kumar Sushil Mahendrapandurang, Saikia Santha, Shasany Ajit Kumar, RanganathanTiruppadiripuliyur Kumar Sushil Dhawan Sunita, Saikia Dharmendra, Patra Nirmal Kumar, Sinha Prachi, Krishna Kumar, Ahmed Ateeque, RanganathanAgarwalSantha, Pandurang, Kumar Tiruppadiripuliyur Kumar Sushil Darokar Mahendra Pandurang, Tiruppadiripuliyur Ranganathan, 195 yAi ua,Ay a 2003/2276 ny Ajit Kumar, Arya Jai r adrn,6767876 dra Pandurang, re ig,Ay EP Preet Singh, Arya ig;Twr US a Singh; Tewari SanyAi 2002/7674 Shasney Ajit etSnh ua ZA reet Singh, Kumar tv ats 1370263 stava Santosh etSnh RU reet Singh, Hrks 6831214 Herikesh e ig,US eet Singh, e ig,ZA eet Singh, SnhTrn US Singh Tarun, Mdn6833143 Madan iyur Ssi,US Sushil,
Annexures CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Annexures lsi usrtsPu nmt,CatpdyyAu 68 Paul Anumita, Chattopadhyay Arun 6852 Bora Pandey U, NathGirdhar J, Kumar, Choudary BM, Vanga Siva, D chlorophyll content and salt tolerance Transgenic plants with enhanced plastic substrates Chowdhury Devas Sharma S Coloured nanolithography on glass and Chaudhuri MK, Dehury fluorochromate (vi) Process for preparing pyridinium Sharma CSIR BD, Shravanaku (SCH) Narasimham VML, B machine for assembly components Singh N, Jain SC, Improved semiautomatic pick & place Gupta SK, Dodd DS, immersionSin probe Fiber optic temperature switching Chhabra DS, Rao PK, driving automobile useful during night An improved antiglare device for Victor Babu,Visalakshi Vijayaraga Jain Subhash Cha Fiber optic point temperature sensor CSIO Victor Narayanan Babu,Visa Chandraku modulator imaging device using high amplitude Electronic paramagnetic resonance Narayanan Chandra bridge translator EPR imaging device using microwave rdetasao itrBb,iaasi2813671 JP Victor Babu,Visalakshi Chandrakumar N Narayanan bridgeChandr translator EPR imaging device using microwave An improved logic device CLRI slto,caatrzto n htejeL CA 6849246 682 Chatterjee LB R Gangadharan mechanism of action of a new Isolation, characterization and lithium metaarsenate (liaso2) Subramania A R Gangadharan solid state method for the synthesis of phosphate lipf6 as battery electrolyte Subramanian A, the synthesis of lithium hexafluoro Chatterjee Indu A new solid state thermal method for harmful oxidant from cigarette smoke Process for the isolation of a major odrGplCada awr6856714 Bajpai Ram Prakash Rajneesh, Bansal Ashu Kumar, Poddar Gopal Chandra, Talwar Kantam ML Mediratta AK Vijayaragavan Sudhir Kumar Bhattacharya Alok, Sopory 196 ,VsdvnT US n A, Vasudevan T, sa eu 6791009 eswal Renu, Bua US Bhusan auea ,US Vasudevan T, asiVjyrgvnGB2366386 lakshi Vijayaragavan gawlA US Aggarwal AK dr ig aa,US Singhnder, Nahar, s,US ish, kmr asyFR akumar, Kassey ua,Kse GB kumar, Kassey Sam D AU Sharma BD, angrR ZA hatnagar R, a,Kse GB mar, Kassey RdyUS Reddy 774644 gh V, K US SK, a R 2003/2234 mar RR, van GB2366387 6726360 3540935 5294765 6782891 33162 4754 859 ,-ylhxdeoeRmcarihGde 6838582 Ramachanraiah Gadde, Ghosh Pushpito Device for estimation of brine density 2,5-cyclohexadienone Bedekar Ash Process for preparing 2,4,46-tetrabromo- Jasra Rakesh Vir Muthusamy, Ba JatinChunnawala Shantilal, preparation of acylated aromatic ethers Clay based catalytic process for the 6740253 US industrial processes Mahasukhray,Ghosh Jasra PushpitoRakesh Vi Kumar, carbonate rich by-product generated in A process for purification of calcium Vohra Rajinder Nath, brominating reagents Preparation of non-hazardous eeae nidcra rcse Rameshchandra, Shet Chunnawa Shantilal, Jasra Rakesh Vir, Oz generated dra inMahasukhray, inductrial processes calcium carbonate rich by-product precipitated calcium carbonate from A process for the production of hmcl rmbieKumar, Mohandas; Vadakke Putho Vohra Rajinder N, chemicals from brine Recovery of common salt and marine Bhatt AM, Chau cyanobacteria calcium ions from the brine by marine Mishra S, Gho An improved process for the removal of algae Reddy Radhakr An improved process for cultivation of CSMCRI smoke: prevention by ascorbic acid hazardous component of cigarette Joshi Himanshu Labhshanker, Joshi Himanshu Labhshanker, ihrMnoa a,Gnh 6865942 Kishor Manmohan Das, Gandhi Patel Virendra Bhikabhai, Mansukhlal, Ayyer Jayalekshmy, Vinodrai, Badheka Yogiraj Vinodbhai, Thakkar Vikram Ghosh Pushpito Kumar Mansukhlal Bhikhabhai Ayyer Jayalekshmi, Patel Virendra Badheka Yogi Mansukhlal, Vinodbhai, Thakkar Vikram Vinodrai, Rameshchandra, Sheth Mrinal Dave Rohit Harshadray, Deraiya Hasina Hajibhai, Gandhi Maheshkumar Ramniklal, Deraiya HasinaDeraiya Hajibhai Pushpito Kumar Mody Kalpana Haresh, Ghosh 6858430Subba Rao Peddi Venkata, Rajakrishna, Eswaran Kuruppanan, Mairh Om Prakash, Kumar Guru 197 ts aat US utosh Vasant, hP,Gnh R US sh PK, Gandhi MR, oaiRjs 6761864 Somani Rajesh ,OaPaicadaUS r, Oza Pravinchandra hk oia 6730814 dheka Yogiraj snCenr US ishn Chennur; Kmr aeti US Kumar, Majeethia egdgudrUS , Sengodagounder a A6812001 han SA GohuhioUS GhoshPushpito Smn aeh6790424 Somani Rajesh rvnhnUS a Pravinchan la Jatinla h Mrunal r 6776972 or,
Annexures CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Annexures muoobn sa hraGid a 2249218 Sharma Gainda Lal GB23607 Nahar Dayaram, Pradip,Manoharan Bora AUtp immunosorbent assay Rapid method for enzyme-linked Gangalwaste-waters SV, useful Kumar for the neutralisationR, of Kumaralkaline A 6 A microbial composition and a process Archana from petroleum refineries Kumar Rita, Shathe treatment Shikha, Makhijani of phenolic waste-water Immobilized microbial consortium for Kumar Rita, Sharma estimation useful for rapid and reliable bod Immobilized microbial Brahmachari SK, Ranja consortium schizophrenia Salim Q, Jain S detection of pre-deposition to mutation in synaptogyrin 1 gene for A method for identification of effluents using mixed bacterial consortia Kumar R, Tik solids (tds) from pulp and paper process for removal of total dissolved IGIB Ghosh Pushpito Kuma Ramachandraiah high purity tetrabromobisphenol-a Eco-friendly method of preparation of Sebastian Jince, Ja a gaseous mixture with oxygen adsorbing nitrogen and argon frommolecular lieve adsorbent for selectively Process for the preparation of a Mahasukhray, Somani R Jasra Rakesh calcium carbonate from calcium Susarla VKS, Vag Process for generation of preceipitated Ramachandraiah forG oxidation of bromide to bromide An improved electro-chemical method Abdulhamid Usmanbhai Hamidani Vadakke Puthoor, Hamidani Chauhan Shantilal Amrital, Mohandas Naranbhai, Bhatt Ajoy Murlidhar, Mahesh Ramniklal, Parmar Jamnadas Misra Misra Sudhindra Nath Vaghela Sanjay Shambhubhai, Popatlal, Jethva Ashok Dahyabhai, Aditya Shantilal, Pandya Rajesh Patel Virendra Bhikabhai, Ayyer Jayalekshmy, Badheka Yogiraj Mansukhlal, Vinodbhai, Thakkar Vikram Vinodrai, Rameshchandra, Sheth Mrunal JatinChunnawalaShantilal, 198 MkiaiS 6846483 Makhijani SD Vr z rvnhnr EP Vir, Oza Pravinchandra K hraPUS u DK, Sharma P m la ua GB rma Alka, Kumar eaS 6811679 hela SS ad,RU Gadde, r VSG sra RV ats 2360788B Santosh hraA US , Sharma A, hs K US , Ghosh PK, la atg GB Alka, Rastogi ,Mha2247105 r, Mehta a hta US na, Chitra, l RU al, ajesh 1440037 B1 1440037 ajesh 6846666 106851 764824 87 irba rnomn Gulati Ashu, Desikachar Srigir Desikachar RS, Sing shoot sorter A continous type multipurpose tea Sandal Indra, microbial tranformant Use of tea leaf extract for inhibiting ldou yrdpat'h an'Dhyani D, Mukherj Gladiolus hybrid plant 'the saint' eih` -Dbss PP15080 Debasish Dhyani D, Mukhe Dhyani Devendra, Gladiolus Mukhehybrid plant 'palampur pride' delight` - Gladiolus hybrid plant `palampur ldou yrdpat'rc'Dyn ,MkejeDU Dhyani D, Mukherjee D Sinha AK, Joshi BP, Dogra Gladiolus hybrid plant 'grace' 2(3h)-furanone chiral 5-isobutyl-3-methyl-4,5-dihydro- dihydrotagetone, and its conversion to Method for producing chiral rcs o h rdcino eblSingh HP, Sin Sinha AK, Joshi BP, Dogra A process for the production of herbal 2(3h)-furanone chiral 5-isobutyl-3-methyl-4,5-dihydro- dihydrotagetone, and its conversion to Method for producing chiral dye, from phenylpropane derivatives trans-cinnamaldehyde, a natural yellow Sinha Process AK, for the preparation of substituted dye, from phenylpropane derivatives trans-cinnamaldehyde, a natural 22490 yellow Sinha Process AK, for the preparation of substituted dye, from phenylpropane derivatives trans-cinnamaldehyde, a natural yellow Sinha AK, Joshi BP, Dogra Sinha Process AK, for the preparation of substituted (3h)-furanone chiral 5-isobutyl-3-methyl-4,5-dihydro-2 dihydrotagetone, and its conversion to Method for producing chiral Dash Debasis IHBT conserved invariant peptide motifs A computer Brahmachari based K method for identifying ie rmhmlynbrisDawlVrne ig 6 Thakur Rajesh, Sood A Dhadwal Varinder Singh Sterile laminar Singh airflow Harsh Pr device wines from himalayan berries Process for the preparation of herbal pashiapyrus wine (palam belle) from ripe fruits of Ravindranath, Ahuja Paramvir Singh hj aavrSnh88039 Ahuja Paramvir Singh 199 JsiB,DgaRTA GB Joshi BP, Dogra R FR Joshi BP, Dogra R Joshi BP, Dogra R Batcay mt,LK Bhattacharya Amita, hB hda SNZ gh B, Dhadwal VS mrSmr RU umar Samir, tp ig rjne,US atap, Singh Brajinder, jeDUS rjee D eDUS ee D KLK h KK i,SG nil, jeUS rjee RSN R RAU R US R prm13019 ipuram 13020 PP15626 PP14980 PP14979 2187344 780476 195651 2373252 03984 01 6833475 517600 793957 S 44
Annexures CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Annexures rprto fay escnsReddy Konatham Saidi, Choudary Boyapat preparation of acyl lessocenes A novel ecofriendly process for the IICT o lcig5lpxgns ciiyPal Bikash Chand Basu Sumanta for blocking 5 lipoxygenase activity Roy Keshab piper betel and Bandyopadhyay murrya koenigii extracts Herbal formulation of a combination of Bandyopadhyay Patak endotoxemia or sepsis (LPS) useful for Bhadra Ranjan, preventing Na patent Chatterjeenontoxic lipopolysaccharide Mita, Sen K A process for the preparation of new penta acetic acid Banerjeediester Some technicetium Chatterjee - 99mMita, diethylene Sen K triamine Process for the preparation of Banerjeepenta aceticSome acid diester technicetium- 99m diethylene triamine Process for the preparation of useful for the treatment of vitiligo endothelin-like constituent peptides Bhadra R, Pal P, R containing glycos phingolipids and extract from human placenta A process for the preparation of an seta isad yrsl Vijay Kumar, Singh Vir Singh Ahuja HP, SinParamvir Singh, A process Babu for theGarikapati productionD K of herbal essential oils and hydrosols apparatus for the production of Simple portable mini distillation Herbal composition for treating asthma Bhadra Ranjan Bhadra 2383753 Herbal composition for treating asthma production, and Roy enhancementKeshab Chandra of GA Das Krishna, Bha Bhattacharya Samir, Ray Mitali, synthesis, suppression of interleukin-4 Chandra, Bhadra leading to the inhibition of leukotriene Chandra, Roy Mitali, blocking of 5 lipoxygenase activity koenigii and piper betle useful for Bandyopadhyay Sa components prepared from murrya Herbal composition of blend of active Bhattacharya Sa and a method thereof acute and chronic myeloid leukemia Bandyopathyay Bandyopathyay Santu, A herbal composition for treating cd33+ leaf extract Antimonocytic activity of betel IICB pashiapyrus wine (palam belle) from ripe fruits of Das Das Krishna, Bhattacharaya Samir a rsn,BatcaaaSmr6746694 Das Krishna, Bhattacharaya Samir Roy Keshab Chandra 200 Chandra, Roy Mitali, EP 1414475 EP Chandra, Roy Mitali, hB hda SKE gh B, Dhadwal VS Nt 3566536 Nath ah953360 Nath a iahCada US , Pal Bikash Chandra, i,RyMtl,6852344 US mir, Ray Mitali, Santu, Pal Bikash, at,EP Santu, ttacharya Samir yR at K EP oy R, Datta AK, ra, Bhadra Ranjan, Bhadra ra, Ranjan, aoajn IT i Manoranjan, a bii,JP yak Abhijit, t,RyKsa US ntu, Roy Keshab iran, PlBks 6773728 Pal Bikash rb,JP EP arabi, arabi, hrn 3595966 i Charan, endr a Kaul a iah GB Pal Bikash, Kna;1268501 Kantam; 3538745 KE188 gnsBhaskar, Diwan Prakash Vamanrao, Kantan L et al. oxides Process for the preparation of amine therapeutic agent Jettyaliphatic acid ester useful asA, Akk A process for the preparation of b-keto Venkata Durga Nageagents Sistla Ramakr thereof and use thereof as hypoglycemic Thallapall Rama hydrazines, process for preparation 1-(aryloxy) propionoyl-2-arylsulfonyl rcs o h rprto fK ahvne.a EP Jayathirtha, Raghav Raghavan Kondapuramvijaya, 5-methylpyridine-3-carbaldehyde Chinaraju B Kantam ML, Rao KK, Pr Process for the preparation of 2-chloro- using alumino-silicates as cataltsts Rahgavan KVmonosubstituted KV Raghavan et. aromatic al hydrocarbons with high paraselectivity from Choudary B Process for the production of nitroarenes amine oxides Process for the preparation of vicinal diols Choudary Boyapati M Kantam Mann asymmetric Chowdari Naidudihydroxylation of olefins to hydroxides exchanged with osmate for Preparation of new layered double clercnsRdyKnta ad,3574805 Reddy Konatham Saidi, Bandyopadhyay Process for Choudhary preparationBoyapati Manoof malononitrile acylferrocenes Process for the preparation of acylferrocenes Reddy Konatham Saidi, Lakshmi 1268501 1268501 Reddy Konatham Saidi, Lakshmi CN116674 Reddy Konatham Saidi, Lakshmi Choudhary Boyapati Mano acylferrocenes Process Choudharyfor theBoyapati preparationMano of acylferrocenes Process for the preparation of -hnlr-intieGlaal, a admet 2 Gollapalli, Rao Maddamsetty 3-phenylpro-pionitrile Ahmed StereoselectiveKama preparation of 3-hydroxy- Yadav Yadav Jhillu Singh, Raghavan Kon Kondapuram Vijaya Choudary Boyapati Manoranjan EP1184369B1 Aziz Khathija, Likhar Pravin Raybaji, Kondapuram Vijaya Lakshmi Mannepalli, Raghavan Kondapuram Vijaya Mannepalli,Raghavan Kondapuram Vijaya Mannepalli,Raghavan Kondapuram Vijaya Venkateswara, Raghavan Kondapuram Vijaya Mannepalli Lakshmi, Raghavan 201 wrD,Rgaa VUS ewar DM, Raghavan KV iaaa a adaUS EPhimapaka, Rao Vaidya M, Sateesh M, ishna, Rao Adari , hse hnaGB l, Bhasker Khanna epalli Lakshmi, igm aaal US Yadavalli lingam, nnaKmr EP Ananda Kumar, Sreenivasa, n6737529 an wr 6730704 swar, anoranjan, EP 1209142 B1 1209142 EP anoranjan, asad KVR, 1004570 B1 1004570 asad KVR, ajn JP ranjan, ajn EP ranjan, CH ranjan, EP1213280 B1 EP1213280 EP 6838083 1209148 B1 1209148 387597 B1 C
Annexures CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Annexures igrpitn n tnadzto fKondapuram Vija single medicines and formulations Dadala Vijaya Kum finger printing and standardization of A novel method for chromatographic nteitgae etmngmn Venkateswaralu Yen in the integrated pest management Rao Janapala Alkylxanthates and use of alkylxanthates 'iouyaeohnn Sateesh Mutyala, Kantam Manne 3532825 Choudary Boyapati Mano Jeevaratnam Katuri, Choudary 4'-isobutylacetophenone Process for the preparation of Kantam Mannepall bromobisphenol-A Process for the preparation of tetra rmtcehr aes uyl,Codr oaai35 Sateesh Mutyala, Choudary Boyapati Kantam Mannepall aromatic ethers Process for the preparation of acyl rmtcehr aes uyl,Codr oaai11 Sateesh Mutyala, Choudary Boyapati Kantam Mannepall aromatic Katravulapalli ethers Veera Process for the preparation of acyl Srinivasan Palan sulfate catalysts usingand polyaniline solid acid Murthybenzene Katravulapallwith tertiary butyl alcohol Narayanan A process for the alkylation of dihydroxy Palan Srinivasan sulfate catalysts usingand polyaniline solid acid benzene with tertiary butyl alcohol Narayanan A process for the alkylation of dihydroxy nipoe rcs o h rprto Kulkarni SJ, An improved process for the preparation etdspoen n acnsJain Sanjain Kumar, R 6800272 peptides/proteins and vaccines Vamanrao, Ragh Chalasani Kishore Vijaya, R for peroral delivery of drugs, therapeutic Narender N, Raghavan particulateKV conjugate carrier systems Vitamin b12 --biodegradable micro Lakshmicatalysts vicinal diols using said multifunctional Chowdari Naidu process for the preparation of chiral Madhi Satee process for the preparation Choudary thereof, Boya and synthesis of chiral vicinal and diols Multifunctional catalyst useful in the of zsm-5 catalyst Raghavan Kondapuram Vijaya Vijaya Venkatasri, Raghaven Kondapuram Lakshmi, Ranganath Kulluri Venkata, Someshwar Thumma Kondapuramvijaya, Sivaji Lanka Reddy Venkat, Raghavan Boyapati Manoranjan, Reddy Chinta Raghavan Kondapuram Vijaya Manoranjan Prakash, Billakantiveda, Raghavan Kondapuram Vijaya Manoranjan, Prakash Billakantiveda, Koteshawar 202 ussell-Jones Gregory John, akrsbir GB Sankarasubbier, FR Sankarasubbier, SiiauP US Srinivasu P, sh, Kantam Mannepalli Vnaehaa EP Venkateshwara, aiMnrna,US pati Manoranjan, vnKnaua 2374010 avan Kondapuram apn utyGB2378441 iappan, Murthy Senvs,6780810 Sreenivasa, apn 2822822 iappan, a42088 ya au ia GB Babu, Diwan asm,JP i Lakshmi, asm,JP i Lakshmi, asm,EP i Lakshmi, r ahvnKR ar, Raghavan Ve amandra, 1373238 B1 1373238 amandra, i Veera VE ao ao Kollipara ajn EP ranjan, al 1138662 palli 49818 B1 49818 32824 er lootaePmlprh hnhnRo 237597 Pamulaparthy Shanthan Rao, Viswanathan Venkataraman 67 Rao Jampani- M tetra Kulkarni Shivanand fluoroethane Jan Madhavi Gangapuram, A process for the preparation of 1,1,1,2 modified zeolites vinylpyridine from picoline over Process for the preparation of Kondapuram Vija single medicines and formulations Dadala Vijaya Kum finger printing and standardization of A novel method for chromatographic natural source Yadav JS, Raghavan KS EP 1411909 B1 1411909 EP 681 Dutta Guru P A Ramprasadsynergistic KV, anti-malarialSri R formulation Choudary BM,Kantam clay catalysts thiophene using metal exchanged Yadav ML, JS, ReddyRaghavan RV,BharathiKS B -nitrothiophene selectively from Process for the preparation of 2 reaction Choudary BM, Ravind diisopropylamide for C-C bond forminghydroxides exchanged with Preparation of 6716996 new layered double polyaniline as salts novel catalysts Palaniappan A Saravanan process C, Chandreshekhar for R preparation of esters Rao using JM, Tiwari A natural source Diaryl butane as antioxidant from a Rao Janaswamy Madhus Rao Rao Jagadeeshwar Singh, Raghavan Antioxidant from Rao naturalJanaswamy Mad source source namely dichrostachys cinerea Palaninappan S, -epicatechin Rao VJ from a new natural Process for the preparation of (-) coumarins Poddutoori Ramulu, O Process for preparing Kamal substituted Ahmed, Gujja anti-cancer agents benzodiazepine hybrids useful as Pyrene-linked pyrrolo[2,1-c][1,4] aayt Ramaswamy R, Ninan KN, Sastri Ramaswamy R, Ninan KN, Sastri Venkatachalam S, S Choudary BM, Kantam ML catalysts KJ, Vijayakumar salts by metal ion exchanged clay preparation of dinitramidic acid and Venkatachalam S, S An ecofriendly process for Choudary the BM, Kantam ML catalysts Vijayakumar K, salts by metal ion exchanged clay preparation of dinitramidic acid and An ecofriendly process for the anDamCad777841 Jain Dharm Chand Veeramachaneni Vijayakumar Banda, Kuppusamy Radhakrishnan, Attaluri Siva Prasad, Narasaiah Kondapuram Vijaya Kumar, Yadav Jhillu Singh, Raghavan 6781002 Rao Rao Jagadeeshwar, Tiwari Ashok 203 ,Sia GB S, Sairam M aah AU rakash, duuaa GB adhusudana, rda ,1344748 Sridhar C, ,SihrC 6787119 K, Sridhar C, ,KmrU,EP K, Kumar US, Kondapuram Kondapuram Vijaya a2003/2435 ya anthosh G, anthosh G, r ahvnZA ar, Raghavan aeh US r Ramesh, naahK 6794521 anganath KV uuaa US husudana, rA atmUS er A, Kantam L US ML, euSiia 6800622 lepu Srinivas aa hlu6841687 , Yadav Jhillu US , ra,US ardan, dn,US udana, anmK,EP, Ratnam KJ, anmUS , Ratnam 2381788 B 2381788 27365 2186 4
Annexures CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Annexures metal phthalocyanine as a catalyst Bhatia Bhatia VK, Rao TSR metal phthalocyanine as a catalyst Kumar S, Kum Bhatia VK, Rao TSR petroleum distillates Sain B, usingPuri halogenated Process for the fixed bed sweetening of metal phthalocyanine as a catalyst Kumar S, Kum petroleum distillates Sain B, usingPuri halogenated Process for the fixed bed sweetening of Kapoor VK, Rai sulphonamide catalyst Sastry BS, KumarYadav JS, S, RaghavanKuma Sain B, Puri SN, extraction using metal phthalocyanine petroleum distillates by liquid-liquid Process for sweetening of lpg, light Rao JM, Tiwari AK, Kumar IIPU treating gastric ulcer New herbal composition 4663for IICT+CDRI Palaniappan S, polyaniline as catalyst salts keto-esters with alcohol using Process for the transesterification of agent Kondapuram Vijaya Jettyaliphatic acid ester A, useful Akkas therapeutic A Dadala processVijaya Kumar, for R the preparation of b-keto formulation Palaniappan S, Amarnath pringing of herbal medicines & A novel chromatographic finger polyanilinesalts Process for Kantam Mannepal Raghavanthe preparationKonda of Choudary Chowdari Boyapati Naidu Mano Sree diols using supported osmate catalyst for the preparation of chiral vicinal preparation thereof, and a process Supported osmates, process for and 5-acyloxy analogues Srinivasof KV campthothecin Das Biswa Process for direct preparation of 5-alkoxy aorsaln elt eaKna L ahvnK 6 Meshram Harshadas Mita Kantam ML, Raghavan KV Kokku Premalath Rao KK, Rao BPC, Choud (substituted-4-quinolyl) disulphides Process for synthesis of bis- nanocrystalline zeolite beta Process for the preparation of aayi ytmKoteshwara, Kumar Thella Prathap, Sreekanth Pentlaval Kantham Mannepal catalytic system of toluene catalysed by composite Selective liquid phase air oxidation Varier PMK, Muraleed Dubey MP, Palit G, Balla DN, Dixit M, Yadav JhilluYadav Singh Madhavi, Begari Eshwaraiah, Boyapati Mano Rao Bhavnari Purna C, Choudary 204 ah ahsda ,US nath, Madhusudhan P, S a,G aoiB,GB S, Das, G, Balodi BP, FR S, Das, G, Balodi BP, S6872829 NS wrD,Rgaa VUS ewar DM, Raghavan KV rA aorV,GB2371556 ar A, Kapoor VK, 2818282 ar A, Kapoor VK, CadaehrRUS R Chandrasekhar ,Bai K GB2373790 r A, Bhatia VK, DsG aoiB,GB Das G, Balodi BP, GP, Rao TSRP puram Vijaya ,Aygr ekt 6777553 a, Ayyagiri Venkata li Lakshmi, P, Rai GP P, Rai GP i a otpli6743952 li, Rao Kottapalli iLkhi US li Lakshmi, iaa 6815566 nivasa, gaa EA aghavan r M US ary BM, C AU CA ajn US ranjan, a,US ram, ,US S, K,6855347 KV, 6743942 6838268 2002242943 827924 n ih erlu itlae Prasad, Kumar Sunil, Gautam,and Balo light petroleum distillates useful for liquid-liquid Sain sweetening KumarBir, P lpg Sunil, Kumar An Process for the preparation of a catalyst Gautam, and Balo light petroleum distillates useful for liquid-liquid Sain sweetening KumarBir, P lpg Sunil, Kumar An Process for the preparation of a catalyst Gautam, and Balo light petroleum distillates useful for liquid-liquid Sain sweetening Bir, P lpg Process for the preparation of a catalyst ih egthlcpe a hsa acadaGB Pai Ramchandra Bhaskar 6 A light weight helicopter NAL and the vaccine Sharma produced Naresh by the process other intracellular infections diseases for the 6774081 treatment Agrewala of Jatuberculosis and Process for the preparation of a vaccine useful in the process thereof thereof, and a universal growth medium Pu Agrawal Bacteriophage, a process for the Soumen,isolation Agarwal Monika IMTECH Bhagwati Prasad, Kapoor Kumar VK, Sunil,Rai sulphonamide catalyst Kumar S, Kuma Sain B, Puri SN, Datta Arunabha, Dasgupta extraction using metal phthalocyanine petroleum distillates by liquid-liquid Process for sweetening of lpg, light pyrophosphate catalyst Process for preparing vanadyl Balodi Bhagwati Prasad, Kumar Nath, Das Gau petroleum distillates Agrawal Brij B catalyst useful for sweetening of sour Process for the preparation of a novel Nath, Das Gau petroleum distillates Agrawal Brij B catalyst useful for sweetening of sour Process for the preparation of a novel ea hhlcaiea aaytBalodi Bhagwati Pr metal phthalocyanine as a catalyst Nath, Das Ga petroleum distillates Agrawal Brijusing halogenated Process for the fixed bed sweetening of Bhatia Virendra Kumar Kapoor Virendra Kumar, Virendra Kumar Virendra Kumar, Bhatia Prakas Sunil, Kumar Anil, Gupta Pushpa Bhatia Virendra Kumar Kapoor Virendra Kumar, Kumar Kumar Anil, Gupta Pushpa, Prakas Prakas Sunil, Kumar Anil, Gupta Pushpa, 205 r o ah a US uri Som Nath, Das GB uri Som Nath, Das FR uri Som Nath, Das e am US ved Naim, ha oiVsa US shpa, Soni Vishal Bhdr uiSmUS Bahadur, Puri Som tm anBr 6755964 utam, Sain Bir, iBawt 6740619 di Bhagwati iBawt rsd GB2371300 di Bhagwati Prasad, 2816854 di Bhagwati Prasad, hdr uiSmGB ahadur, Puri Som FR ahadur, Puri Som a,Si i,Bld GB2372501 tam, Sain Bir, Balodi 104388 tam, Sain Bir, ,Bai K 2822837 r A, Bhatia VK, DsG aoiB,FR Das G, Balodi BP, GP, Rao TSRP asad, asad, Kumar Kumar Anil, il, Kapoor il, 23384224 6787360 US 783765
Annexures CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Annexures ehdfrteipoeeto Choudhary VR, Choudha fluidized bed reactor gas-solid contacting in a bubbling A method for the improvement of opiigbceilsriso ceso Pushpangadan comprising bacterial strains of Nautiyal accession SC, A synergistic bioinoculant composition NBRI oyeial armradKlan G hnaeJ U Sanjeevani Amrit, Sudalai Swaminathan Kulkarni MG, KulkarniKhandare MG, JJ Khand Sudalai Copolymers Arumugam, andSiv preparation thereof preparation thereof Polymerizable Sanjeevanimacromer Amrit, and Sudalai -tetraminobiphenyl of pure high quality 3,3',4,4' GD, Tamhankar SS, ManerSeetaramar Asif, An improved process for the preparation Thakur Vinay Vi arenes chlorination of alkanes, alkenes and Kundalik D A new Laxman catalyticRS, process More S for regiospecific US metals by actinomycetes Dewkar Gajanan Kundali A process for the removal of heavy Thakur Vinay Vijayraj Shingte RD, Wadgaonkar PP phenol hydroquinone and quinones from Malshe Kusum 1 MadhukarProcess for the production of preparations Patil Pratap Tukaram, alkylcyclohexanes, method for their 1,1-bis(4-aminophenyl)-3- Dongare Mohanmolybdenum K silica catalyst benzene using nitric acid over Process for vapor Khatoon phase Sayyada, nitrationGovindarajan of P Pushpangadan NCL lentimorbus from cow's milk bacterial strains of b.subtiles or b. Nautiyal SC, Meh A bioinoculant composition comprising in vitro Tuli R, Srivas large number of viable cotton plants Tissue Shanta, cultureRawat Ajay process for producing a Pushpangadan Palpu, applications colours useful for cosmaceutical A process for preparation of herbal producing said composition thereof and NRRL B-30488 and a method of Nos. NRRL B-30486, NRRL B-30487 Arumugam, Devotta Sukumar Arumugam, Devotta Sukumar Raghavan 206 wa aaa,US ewkar Gajanan, uhrBvkr US Sudhir Bavikar, aaA,GpaS CN tava AK, Gupta SK et ,SnhH,ZA Mehta S, Singh HB, P2003/2288 P arj ady6825383 jayraj, Pardhy aS ig B ZW ta S, Singh HB, rb,US eraba, ,SaaueZA V, Shahapure ua ig,2374284 Kumar Singh, r JUS are JJ ady6872857 , Pardhy Mhor GB Mehrotra rm6835854 aram yT US ry TV ,US k, oB2003/2502 ao B 6846932 6825308 6822064 6790993 6791000 ZL97103003.0 1/2003 S ihcroy ru akeeVjySpn nukr68 Narkhede Vijay Sopan, Indurkar with carboxyl group Kumar Pradeep, ChoudharyFern Vasa Process of aromatic carboxyl compound glycolic acid Agustinho, Gupta enantiomerically pure cyclohexylphenyl Process for the synthesis of of Kulkarni Bhaska Kumar a Viruthiamparambsystem or process Ghosh Ananda advance detection of unsafe operation of identification of safe operation and Method and apparatus for online of meso-substituted dipyrromethanes Naik RH, Jos An improved process for the preparation faihtcachl ocroyi cdDvkrS 6 6 6794467 Deendayal, Ahmad Absar, Sastry Asmita Ashut active Joshi Rohini azabicyclo heptanone derivatives Process for Badiger the Manoharpreparation DivekarVirupax, of SS optically of aliphatic alcohols to carboxylic acid Chaudhari RV, 982334An improved process for the Mukherjee conversion Priyab sulfide nanoparticles Lele Ashish Kishor, Va Process for the preparation of metal Shinde Madhuri Himmatra polymeric absorbents Musale Deepak Ana Process Sivaram KulkarniSwaminathan for Sudhir the Sharad preparation of Madhukar, as an Priya additive L, Chaudh polyacrylonitrile, using malic acid ultrafiltration membranes of Process for the preparation of for the preparation thereof Jyoti Prakash Conductive polymer blend and a process macromonomer Ramanathan Lalg Process for producing polycondensable iyi idrdaielgtsaiiesDesai Shroj Vinylic hindered amine light stabilizers ilfntoaie vasresSnhRjPl675649 Shuban Kishen 878484 Ramchander TVN, Rawal EP Kelkar Ashut Process for the preparation of polyesters polyhydroxybutyrate Pal Singh Raj Mahishi LH, Tr Pta 1579 and its use to produce Escherichia coli having accession no. Thanki Paragkuma Sivaram Swaminathan diol-functionalized uv absorbers Process for the preparation of novel Sensarma Soumen, metallocene catalyst megnesium halide supported A process for the preparation of a Jayant Ravichandra Anna, Gurjar Mukund Keshav Raghunath Vitthal Mashelkar; Mashelkar; Raghunath Anant 6737528 Pal Singh Raj Kulkarni Shrikant Madhukar, 1229064 B1 1229064 Chaudhari Raghunath Vitthal Kulkarni Shrikant Madhukar, 207 lMhtua,US al Mohitkumar, Rms,Pahn US Ramesh, Prabhune iP US hi PL Jg ukriSrkn US Jog, Kulkarni Shrikant s nn,EP osh Anant, s,JsiRms 6780635 osh, Joshi Ramesh JsiS,Kla A US Joshi SS, Kelkar AA, mohan ptiG US ipathi G, attaa 6826513 r Dattatraya, tRmcada,US nt Ramachandran, aa adlUS rata, Mandal d rnvsn EP udi Srinivasan, Pi 6825378 Prii ahll US r Nathalal, ndrao ne onyUS andes Rodney geeSyi US rghese Shyni, hnr,US chandra, t ai US ath Ravi, ,6858141 o, r 6800221 ari 6852864 6756222 858753 783963 28463 9
Annexures CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Annexures rsuetasuesMhaP eaE avkrS 684 6786087 Mehra P, Desa E, Nagvekar Sm Naik GP, Desa Bae, Madhan unprocessed Baracho multi-beamJ, Jo backscatter datahybrid layout with the use of susing artificial neural network (ann) Chakrabor A novel system for seafloor classification Joseph A, 6728 Kumar pressure transducers An improved system for calibration of Desa ES, Pasco for coastal waters A controlled thruster-driven profiler Chadha Rajender Kumar, NIO 6777219 Mandal Prantik, moderate size earthquakes Method Gupta OP, ofNageshwarar short term forecasting Vijay, Rele Meenakshiof Vilas, exploration (scale model studies) induction device for deeper depth Moving surface electromagnetic NGRI Laxman Ryali Seeta, Mo alkaline protease Process for the preparation of Sangita Uday, Ahmad Abs NCL+CLRI Dash Chandravanu, P produces a protease inhibitor Alkalothermophilic bacillus that pure-3 phenyl -3 hydroxy propylamine An Kumar improvedP, Pan process of enantiomerically rcs o rprto SlnySalnr ig,67 Solanky Shailendra Singh, US Desai Shrojal Mohitkuma process for preparation Antiozonant cum antioxidant, Mashelkar Ragh Vaidya Kulkarni MohanAlankar G Arun, enzymes Lele Bhalchandra and use thereof for the separation of process for the preparation thereof, containing enzyme specific ligands, Thermoprecipitating polymer rcs o h rprto fehlKalkote Uttam Ra Dongare MK, Patil PT, 3-ethoxy-4-ethoxycarbonyl-phenylacetate Mukund Kesao Process for the preparation of ethyl 4-nitro-o-xylene Process for the preparation of Jogdand Vithal Venkatrao, Rajachandran Kumar Narendra, Satyamurthy C Subrahmanya, Sarma C. Surya Prakash, Satyanarayana Hari Venkata Rao Mala DeshpanBalachandra, Rao Bommaraju Seeta Rama, Rao Mala Balchandra Deshpande Vasanti Vishnu, PalSingh Raj Naik SanjayJanardhan Vidyadhar, Kadam Suresh Mahadev, 208 yB oaaiV US ty B, Kodagali V, ehA6763303 seph A yR US dy RK lAd,MhaP US al Amds, Mehra P, oh hern 6818786 , Joshi Shreerang unath Anant atg a rsn,US Rastogi Bal Krishna, V rbuea ,US V, Prabhudesai S, ro ujrUS mrao, Gurjar hia,6867268 Shripad, opalkrishna, atr US hadtare aseK US Malshe KM eSea US re Snehal oUS ao ,US r, r 6846664 ar, 6720771 6838581 6825388 70785 8292 640 crmctlsKn,KmrSna,DsUaSne 674 Kant, Kumar Sanjay, Das Uma Sunker 6733564 Rao Patcha Ramachandra Rao Venkatesh, Singh Banshi Dhar, Chand Prem Das Swapan Kumar, Sing magnet alloy powder neodymium-iron-boron permanent Process for the production of Das Samar, Das Swapan ceramic tiles Process for the production of iron oxide by biomimetic route Sinha Arvin Process Sahu for Kamala theKant preparation of nanosized spent catalyst Anantha Process for recovery of nickel from Thelakkat, Sreepada Raya NML process for preparation Achuthankutty thereof C Desai Ulhas shrimp Mano penaeus monodon and a syndrome virus (wssv) infected tiger Composition for treating white spot ocean color sensor Chakraborty B, BarachoKoda J, the J backward direction using a satellite scattering function of ocean wateres in Method of determining Wahidullah Solimabi, the B volume Siddharth Hariba, D's Maria Lisette D preparing the same antifungi properties and a process for compound corniculatonin having Composition containing novel containing the said dye and their uses marine invertebrate, compositions Usha G, Anut Natural fluorescent dye obtained from a Mitra Debasis, a source of anti-hiv activity Indian green mussel (perna viridis) as plant salvadora persica l Goswami Usha an extract obtained from a mangrove Biologically active aqueous fraction of rcs o rprto fxlns iia sa68332 Joseph A, Prabhudesai S, Tengali Giriyan Asha Bhosle Narayan Bab A tide staff system process for preparation of xylanase `Pseudomonas stutzeri` strain and rsuebsdssesPrsotm oehAtn,239 Purushottam, Joseph Antony, Desa Ehrlich, Naik Gaj pressure based systems Pressure housing for in-water Chatterji; Anil medium tachypleus gigas in leibovitz culture Bhonde Ramesh In vitro production of amoebocytes from Rao Rao Venkatesh, Rao Patcha R 6802219 Kumar V, Monteiro R Desa E, Mehra P, Sukerkar A, Prabhu, Nagvekar Surekha Mahesh Kumar Vijay, Desai Shivanand Desa Elgar Stephen, Mehra Prakash, 209 sp 6868361 oseph A ,CarbryJi US d, Chakraborty Jui, s GB osh G CatriAi US Chatterji Anil e umenL enne aaieUS , Fernandes Nazarine Rmhnr,US Ramchandra, itr3867 hittur a,PE har, ,Pne US a, Pandey ro US urao, aiV US gali V, ua6777004 ouza Avn 6855186 Arvind nnGB anan K 6800271 K, US hosak au US h Karun urgad US , S US S, GB237388 6770302 6753021 6790659 0163 B0163 3383 59
Annexures CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Annexures ?TIYRXFAOESai ig aidrEP1381619B Swami, Singh Rajinder Maurya Rakesh, Handa 4?-TRIHYDROXYFLAVONE 8-(C-ß-D-GLUCOPYRANOSYL)-7,3?, and method for Mauryathe Rakesh, treatment of diabetesthereof, pharmaceutical composition Swami, Sin 4'-trihydroxyflavone, process of isolation 8-(c-.beta.-d-glucopyranosyl)-7, 3', leocais s hro irm ig hpne,6 Vikram, Singh Bhupinder, Gupta Vishwa Nath alkenoic acids, use thereof Process for the synthesis of trans- auatr hro,mxuefrueSra K124520 Kumar, Chan and Koul a Saraswati, processDh for the preparation thereof Compensated sulphonated polyaniline Chandra Ramesh Sharma CP, Sharma RK, the preparation thereof Sarkar AK in a reusable heatpack and process for Varshney Pradeep, Sharma Nidh manufacture thereof, mixture for use Reusable heat pack, method of manufacture of said relaxor material Vinay, Kashy relaxor material Ramachandran 771 Ramad therefor and method of Lead iron tungstate Jaincapacitive transducer, Kaml electrochromic coatings Deepa, Agnihotri precursor material useful for the Kumar, Chandra Subh 2002 A process for the Kant, preparationKumar ofSanjay, solid Das Uma Sunker thereof and Koul a Saraswati, Dh process for the preparation Compensated sulphonated polyaniline Sharma CP, Sharma RK, the preparation thereof a reusable heatpack and process Sarkarfor AK manufacture thereof, mixture Das forSwapan useKumar, Sing in Reusable heat pack, method of NPL ceramic tiles Process for the production of rnhdalccmn lne aaa 6752865 Bhan MK, Taneja SC, Chandra S, Dutt designated as cymbopogon rljcci Narayan rich in geraniol and geranyl Shahi acetate AK, Shar Drought tolerant strain of cymbopogon Bansidhar Nayak, M RRL (JM) iron hydraulic cement clinker Process for manufacturing of high RRL (BHU) Parkash, Handa Sukhdev Swami Avtar, Satti Naresh Kumar, Suri OmChandan Bal Krishan, Suri Krishan Verma V, Verma V, Zahoor S, Kaul Chandra Chandra Ramesh 210 s ua,KmrUS esh Kumar, Kumar hRjne 6777392 gh Rajinder r uhs EP1118631B1 dra Subhas, pSbahCad6715358 ap Subhash Chand aS,PlS US ma SN, Pal S, P aynS,PP15595 P, Balyan SS, ad uhe US Handa Sukhdev Shsn ,GB Suhasini A, wnSnepEP awan Sundeep JP awan Sundeep hrwjUS , Bhardwaj saVbuiUS isra Vibhuti Raina RK, s 3592991 as, v,GB2359304 evi, uhe EP Sukhdev atC EP Kant C, AU Kant C, au AU h Karun i 852759 018 249548 7 B1 7 1 preparation thereof Nair, Nair, Pillai Chennakkattu Vadakkethonippurath Vijayanathan Vee preparation thereof terpolyesters and process for the Melt processible liquid crystalline niatra ciiyteefSethi Vijay Kumar, An Ashok Kumar, Verma Vijeshwar Subhash Taneja Chandr antibacterial activity thereof cymbopogon flexuosus and (+)-1-bisabolone isolated from rd ytei uieadpgio Sasibhushanan S, Das PNNM, Bhat KH grade synthetic rutile and pig iron Process for the preparation of high mesogens novel monomers having azobenzene Chennakkattu Krishna S preparation thereof, polymers and network structures, process for the Saminathan Muthu mesogenic groups in cross linked polymers of having azobenzene Liquid crystalline polymer films of eai opstosxoyao-JwhrI 6800577 Achutankunju, Nair Sumathykutty Manga Rao Janaswamy Madh a process for preparing US the same the plant humboldtia decurrens and Anti-diabetic agent obtained from Mary, Koshy J James Jose. J nanoparticles of ceramic oxide powders Single step process for the synthesis of the same Jawahar In or 1:4:9) and devices comprising Sebastian MT, Sa ztio2(m=sr,ca; x:y:z=1:2:4, 2:2:5, 1:2;5 Qazi GNceramic compositions xmo-yla2o3- BrothakurA N set of novel microwave dielectric and oxygen Qazi GNhydrogen peroxide from hydrogen A process for the preparation of Ahuja A,RRL Koul S, (JT)Ka swertia chirata ham Verma NK, K Handa Sukhdev Swamiformulation for in vitro regeneration of Ahuja A,Synergistic Koul tissueS, Ka culture media swertia chirata ham Verma NK, K formulation for in vitro regeneration of BhagatSynergistic Asha, tissueGupta cultureK media Guptaantidiabetic Om composition Praka from argyrolobium roseum and its A process for the isolation of extract Krishna Sadasivan Krishna Mohanty BCR, Ray HS Sivakumar Rajagopal, Das KOT Rathinam Kodandaraman, Damodaran Alathur Damodaran, Prabhu, Bakshi Sanotosh KumarI Singh, Hashmi Abid Zaffar, Dutt 211 s aa,Jh saUS ose Rajan, John Asha u K an K 2004/4059 aul MK, Raina RK, 6855547 aul MK, Raina RK, cb6835367 acob h ha aer US sh, Ahmad Zabeer, taN,US ntha NI, a rsdGB na, Prasad uhre ,770237 Mukherjee P, ay iliUS samy, Pillai lB,ZA US ul BL, ul BL, aaiMK AU , Janaki MEK, Gopalan Vijay, t 2001242730 ttu lepKmr 6869625 uldeep Kumar, dotra Samar iaktyGB2360778 u Sivankutty sdn,AU usudana, ,SaiUS Shahi a, dsvn 6765079 adasivan, 6787674 , 6761874
Annexures CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Annexures igese rcs o h ytei fJames Jose, J Single step process for the synthesis of waste gases Swachchha EP 1438120 B1 1438120 EP Swachchha Krishna Sadasivan, Sivankuttynair, ZAfor the preparation Prasad Vadakket thereof crystalline terpolyesters and process Thomas, Pillai Biju Vasudeva Melt processible thermotropic liquid RRL (TVM) + DST Haridas Aji waste gases Biological filter for the purification of Das Suresh, Kakkudi for preparation thereof Squaraine based dyes and Haridas process Ajit Device for treatment of wastewater newly developed substrates Alathur Damodaran John Asha Mary, and bi(2223)-ag thick films on these phase pure superconducting bi(2223) and a process for the preparation of Sajith Poo Koshy Koda Jacob, sn Kur and hf), for bi-cuprate Krishnan Su superconductors ceramic substrate ba2 dymo5.5 (m=zr, Process for the preparation of novel applications therapeutical and industrial sensitizers for photodynamic, Danaboyina Ramaiah, Thazhathveetil preparation thereof and use thereof as squaraine based dyes, process for the Heavier halogen atom substituted nanoparticles of ceramic oxide powders Mary, Ko Unni Santosh, Velate Suresh Ravindranathan Ravindranathan Marayil 212 h ao 6761866 shy Jacob ,Mjma EP t, Majumdar s aa,Jh saUS ose Rajan, John Asha dersan, Jose Rajan, rn a ueh6770787 Arun, Das Suresh Pla hnaktuGB2360777 Pillai Chennakkattu 3554910 n, Kumar oiprtuGB honippurathu JP ian Jose, Damodaran i ereDE yil George KlitUS Kalliat ,10196853 n, 2003/2233 DITmlaa RGLPD20,Vl4,p 8-3 10.0 10.120 pp2088-2095 Vol 103, 2004, ppVol 489-533 2004, 43, PROG ppVol8, 2004, 251Iss 104, LIPID BLOOD 11, ppVol 2004, 3110- Iss 16, 2004, vol. 3, ISS 7, pp 482-48 Tamilvanan BLOOD PLANT CELL Bandyopadhyay-G CDRI Nat Mater Garcia-A IICB Aharoni-A IICT Shankar SS NCL NCL IMTECH Issac-B GENOME RES 2004, Vol 14, Iss 9, 9, Volpp 2004, 1756-1 Iss 14, 26, ppVol 2004, 34 Iss 43, ANGEW CHEM GENOME RES George-SJ RRLTVM Issac-B IMTECH C adyGACUT 04 o 7 s ,p 0-1 15. 15.0 Vol 2004, 11, 9, Iss pp 894-9 NATURE STRUC Vol 2004, 37, 3, Iss pp 201-210 IF ACCOUNTS 2004, Vol 37, 1, Iss pp 21-30 Sankara- ppVol9, 2004, 3705-37 Iss 104, ACCOUNTS CCMB Pandey-G CHEM REV pp Iss 6 Vol5658, 303, 2004, pp Iss 467 Vol6982, 428, 2004, NCL SCIENCE Nair-V RRLTVM NATURE Roy-JJ AFFL Pal Bhadra-M RRLTVM Aggarwal-RK CCMB JOURNAL TITLE / AUTHOR CCMB LAB IICT Sharma-GVM ANGEW CHEM 2004, Vol 43, Iss 30, 30, ppVol 2004, 396Iss 43, ANGEW CHEM 39, ppVol 2004, 5130- Iss 43, ANGEW CHEM Sharma-GVM IICT Nair-V RRLTVM DITiah-PMDRSRV20,Vl2,p 311 7.7 7.788 7.889 2004, Vol 29, 1, Iss pp 45-74 2004, Vol 25, pp 93-131. Vol 2004, 25, pp 66-92 MED PROG RES POL REV MED RES REV Vol 2004, 48, pp 1-169 Yesodha-SK Tripathi-RP ADV CATAL RRLTVM Srivastava CDRI 8 9, Volpp 2004, Iss 24, Ratnasamy-P MOL CELL BIOL CDRI Shivaswamy-S NCL 40,Vol 2004, Iss 43, ANGEW CHEM Vol 2004, 44(2),pp 322-325 CCMB ANGEW Vijayaraghavan-R CHEM Choudary-BM CLRI IICT TOP PAPERS WITH IMPACT FACTOR (IF) > 5 PUBLISHED BY PUBLISHED 5 > (IF) FACTOR IMPACT WITH PAPERS TOP aaaa- MOL BIOL narayanan-R RES CHEM RES CHEM RES INT EDIT INT EDIT YM SCI INT EDIT INT EDIT INT EDIT 213 p 3356 8.427 pp 5363-5366 NEUE II - ANNEXURE 5630 8.142 3596-3606 232 8.427 22-3425 -5210.120 4-2522 -958.427 1-3965 011.579 00 10.778 8 96229.162 69-672 1110.679 3131 6 9.635 766 158.427 5135 4730.979 -467 121.036 21 CSIR 7.759 .427 88 000 00 00
Annexures CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Annexures CSMCRI Bhattacharya-A PROG POLYM 2004, Vol 2004, 29, Iss 8, PROG POLYM Bhattacharya-A CSMCRI CMRI Zhang-S PROG POLYM 2003, Vol 28, Iss 11, pp11, Vol 2003, 1517-1 28, Iss PROG POLYM Zhang-S CMRI GBScdv- IIFRAIS20,SP1 6.701 6. 16 SEP 2004, BIOINFORMATICS 2004, Vol 20,6, pp 813-7 BIOINFORMATICS Sachdeva-G 2004, Vol 20, No 7, pp 107 BIOINFORMATICS 6.788 Grover-D IGIB 6.7 Sharma-R Vol 2004, 20, Iss ppVol3, 2004, 20, Iss pp8, 358-360 BIOINFORMATICS IGIB pp9, Vol 2004, 20, Iss BIOINFORMATICS IGIB pp16, Vol 2004, 2 20, Iss BIOINFORMATICS Vol 2004, 20, Iss pp8, 381-387 Bhasin-M TRENDS IMTECH Sharma-D TRENDSIMTECH IN Kaur-H IMTECH Dube-A CDRI Das-A IICB MEHCmor UROI 04 o ,p 6-6 6.869 Vol 2004, pp1, 113, Iss 171- J ALLERGY Vol 2004, pp7, 262-266 231-293169, ppVol 2004, Pramod-SN CURR OPIN 2004, Vol 18, Iss pp12, ADVU770-U786 POLYM CFTRI CELL DEATH Cameotra IMTECH Desai-SM pp 191 10, 117, Iss Vol 2004, FASEB J pp 3735- 17, 117, Iss Vol 2004, NCL Sen-N J CELL SCI Mitra-R IICB J CELL SCI Vol. 2004, 12, Iss 16, pp Bharathi-V 7. CCMB Advan Mater Dhawan-J CCMB Vol 2004, 22, Iss pp4, 181 Vol 2004, 27, Iss 2, Selvakanan-PR Vol 2004, 22, Iss pp3, 142-146 CCMB DIABETES CARE Viswanathan-V NCL TRENDS CLRI Thanikaivelan-P TRENDS pp 49 20, 130, Iss Vol 2003, DEVELOPMENT CLRI pp 5975 24, 130, Iss Vol 2003, pp5, Vol 2004, 1007 131, Iss DEVELOPMENT Singh-P DEVELOPMENT Pallavi-SK IMTECH Vol 2004, 55, Iss pp1, 13 Reddy-TV CCMB ANN Bajpai-R NEUROL CCMB Ragothaman-M CCMB IGIB SCI PARASITOL PARASITOLOGY CLIN IMMUNOL IFR20,Vl1,Is8 p94967.008 MICROBIOL Vol 2004, 11, Iss pp8, 924-936 SCI DIFFER BIOTECHNOL BIOTECHNOL SCI 214 p77847.759 pp 767-814 p44477.501 pp 474-477 2-2 6.701 421-423 4511 6.701 1405-1412 96917.305 966-971 -3 7.717 0-133 5-786.701 751-2758 187.517 -188 -06.701 4-80 144 7.663 31-4941 7 6.831 173 11 7.663 -1016 -927.250 1-1922 58 7.663 -5987 3 7.759 538 787.250 3748 6.955 7.172 701 517 88 IMTECH Bhasin-M NUCLEIC ACIDS 2004, 2004, Vol 32, pp W383-W38 NUCLEIC ACIDS Bhasin-M IMTECH NCL Dandekar-DH NUCLEIC ACIDS 2004, pp4, Vol 2004, 32, 1 Iss pp16, Vol 2004, 20, Iss NUCLEIC BIOINFORMATICS ACIDS Dandekar-DH pp17, Vol 2004, 2 20, Iss BIOINFORMATICS Prakash-T NCL Pandey-N IGIB IGIB IMTECH Bhasin-M NUCLEIC ACIDS 2004, 2004, Vol 32, pp W414-W41 NUCLEIC ACIDS Bhasin-M IMTECH IGIB Saini-AK J BIOL CHEM 2004, Vol 279, Iss 48, 5014 48, pp Iss Vol 279, 2004, J BIOL CHEM Saini-AK IGIB IICB Bhatta J BIOL CHEM 2004, Vol 279, Iss 12, 11259- 12, pp Iss Vol 279, 2004, J BIOL CHEM 6.495 23 22, pp Iss Vol 279, 2004, 43 42, pp Iss Vol 279, 2004, Bhatta J BIOL CHEM J BIOL CHEM 38969 37p Iss 279, Vol 2004, 45, Iss Vol 279, 2004, IICB pp Vol 2004, 5880-89 23, Bhasin-M J IMTECH BIOL CHEM J BIOL CHEM Tiwari-S Vathipadiekal-V ONCOGENE IMTECH Vol 2004, 1, 126, Iss pp 2 J AM CHEM NCL SOC Singh-J Naryan-S 2003, Vol 125(1),pp 42-4 RRLJAM J AM Ganguli-M CHEM SOC CDRI Vol 2004, pp 126(21), 683 Vairamani-M J AM CHEM SOC IGIB Choudary-BM Iss Vol 126, 2004, IICT 11, 126, Iss Vol 2004, J AM CHEM SOC Chandrasekhar-S J AM CHEM SOC IICT p 8, Vol 2004, 126, Iss Choudary-BM J AM CHEM SOC IICT Choudary-BM 41 Iss Vol 126, 2004, IICT J AM CHEM 10757-10 126,pp VolSOC 2004, Gourishankar-A 6.5 J AM CHEM SOC IICT NCL 6.575 Kamat-PV pp1 126, Vol 2004, RRLTVM 21 126, Iss Vol 2004, J AM pp3, Vol 2004, 32, 1 Iss CHEM SOC Herrikhuyzen-JV J AM CHEM SOC NUCLEIC RRLTVM ACIDS 2;32(1):201-10 Jan 2004 Arunkumar-E NUCLEIC ACIDS RRLTVM Varshney-U 2004, Vol 32,10, pp E80 NUCLEIC ACIDS CDRI Singh-SR 2004, Vol 32, pp W559-W561 IGIB Kumar-P NUCLEIC ACIDS IGIB Singh-B IMTECH charyya-SN RES RES RES RES RES RES RES 215 2 p1561576.516 13586-13587 42, pp 011076.516 0021-10027 p69-586.516 pp , 6590-6598 p1161176.516 , 13186-13187 pp p 72-73 6.482 47024-47033 pp p39-376.516 pp 3396-3397 2229 6.516 p 2292-2293 7-286.575 6.701270-1278 2886-2888 1-076.575 018-1027 6.516 3 -76.516 6-27 0-906.701 904-2910 6.516 3 6 6.516 762 6-36 6.482 262-23266 6.482 595-43603 6.575 9 6.575 9 3976.482 -38977 -04 6.482 2-50149 16 6.482 11263 6.575 75
Annexures CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Annexures NCL Vaidya-SR J Virological 2004, 2004, Vol. 119, 1, Iss pp 7 5.250 ppVol5, 2004, 1271Iss 341, J Vol 2004, Iss pp2, 342, 605-61Virological Vol 2004, 76, 1, Iss pp 98-104 5.766 14, ppVol 2004, 4237-4240 Iss 76, J Vaidya-SR MOL BIOL ANAL CHEM J MOL BIOL 5.914 5.883 NCL Acharya-P ANAL CHEM 13, ppVol 2004, 3505 Iss 76, CCMB Qamra-R Vol 2004, pp4, 656-668 Vol 2004, 53, 5, Iss pp 723-728 Pal-A 2004, Vol 38, 1, Iss pp 38-48 CCMB ANAL Pal-A CHEM PROTEOMICS IICB Nagaveni-V IICB Garcia-A PLANT J Vol 2004, 55, 2, Iss pp 196-1 6 IICT GUT BIOL PSYCHIAT IICT Chandak-GR Vol 2004, 11, 4, Iss pp 427-437 Vol 2004, 21, 3, Iss pp 454- Baba-K Vol 2004, 11, 5, Iss pp 713-723 CCMB MOL BIOL EVOL Verma-R NBRI CHEM BIOL CHEM BIOL IGIB Joshi-MB Majeti-BK CCMB 6 Singh-RS p 52, Iss Vol 278, 2003, pp27 26, Iss Vol 279, 2004, IICT IICT Akhtar-MW J BIOL CHEM pp29911- Vol 279, 2004, J BIOL CHEM pp55042-50 Vol 279, 2004, CCMB Shivakrupa-R pp304 29, Iss Vol 279, 2004, CCMB Jeromin-A J BIOL CHEM J BIOL CHEM Srivastava-KK CCMB J BIOL CHEM Asthana-N, CDRI CDRI Kumar-P CFTRI CCMB Khurana-R ENDOCRINOLOGY 2004, Vol 145, Iss 12, pp Iss Vol12, 145, 2004, ENDOCRINOLOGY Khurana-R CCMB TOP PAPERS WITH IMPACT FACTOR (IF) > 5 PUBLISHED BY PUBLISHED 5 > (IF) FACTOR IMPACT WITH PAPERS TOP ILCE 04 o 7 5) p.56-56 6.482 pp.55760-55769 Vol279 (53), 2004, J BIOL CHEM Methods 216 28-29 6.482 52188-52194 p 06.482 20 4557 5.063 5465-5470 95.225 -9 6 6.050 462 5-76 6.482 158-27167 96.039 99 18 5.239 -1281 5.250 -3509 53426.482 25-30432 5.239 7 CSIR 5.250 6.129 .129 .482 .Cara,CI dioyBad1.Prof. André Bétei 12. Chairman, CSIR Advisory Board 5. Principal Scientific Adviser to 4. .Member (Science) 3. .Mnse fIdsr (Shri B.S. Baswan) Minister of Industry 2. 1. Minister of Finance New New Delhi –110 011 Minister of Finance 1. Members Indian Institute of Science New New Delhi –110 067 Chairman, ICSSR 012– Bangalore560 Indian Institute of Science Director (Prof. Goverdhan Mehta) New Delhi – 110 001 Mumbai Mumbai – 400 051 Bandra, Kuria Complex ICICI Tower (Shri N. Vaghul) Chairman, ICICI 11. New Delhi – 110 001 Maulana Azad Road Vigyan Bhavan Annexe Room No. 319 (Dr. R. Chidambaram) Government of India e eh 1 0 Bahadurshah Zafar Marg, ITO Indian National Science Academy (Prof. M.S. Valiathan) President 10. New Delhi – 110 001 Yojana Bhavan, Sansad Marg (Dr. V.L. Chopra) Planning Commission Udyog Bhavan Dr. Dr. Rajendra Prasad Road Bhavan Shastri Ministry of Human Resource Developm New Delhi – 110 001 Udyog Bhavan (Shri Kamal nath) ot lc .Secretary 9. Department of Secondary and New Delhi- 110 001 North Block (Shri P. Chidambaram) e eh 1 0 Department of Industrial Policy Secretary, Industry 8. Department of Information Technolo (Shri K.K. Jaswal), Electro 094–560 Bangalore New Delhi – 110 001 Antariksh Bhavan, New BEL Road 2, Rafi Marg Bhavan Anusandhan (Shri Kapil Sibal) (Ex-Officio) Vice President for Science & Technology Minister of State Chairman 6. South Block, New Delhi 110 011 Prime Minister’s Office Dr. Manmohan Singh (Ex-Officio) President Hon’ble Prime Minister of India Members of the CSIR Members Societyof the (2003-2006) 217 .Secretary 7. Aruna Asaf Ali Marg ICICI Bank Limited New New Delhi –110 002 New New Delhi –110 001 Higher Education Udyog Bhawan & Promotion (Shri A.K. Jha) Delhi – New 110003 6, CGO Complex Lodi Road (Shri G. Madhavan Nair) Indian Space Research Organisation l l e , FB A NEUE III - ANNEXURE nics Niketan gy e n t
Annexures CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Annexures 0 r aj ig*Secretary Dr. Lalji Singh* 20. 9 hiD wrp Secretary JN Centre for Advanced Scienti Shri D. Swarup* 19. Dr. R.A. Mashelkar 18. 7 rf rks .Tna Chairman Prof. Prakash N. Tandan 17. 6 rf nlGpaDepartment of Genetics, Prof. Anil Gupta 16. 5 r so hnhnaa100, Centre Point Dr. Ashok Jhunjhunwala 15. 4 hiHr hriaChairman and Managing Director Shri Hari Bhartiya 14. 3 hiCK il 1 Dr. S.R. Shetye* 21. Shri C.K. Birla 13. *Also member of CSIR Governing Body uiatOgnssLd BHEL House Sri Fort Jubilant Organosys Ltd. etefrClua oeua ilg Block – 2, 7 Centre for Cellular & Molecular Biology Director oeneto ni New Mehrauli Road Technology Bhavan Department of Science & Tech New Delhi – 110 001 North Block Government of India Ministry of Finance Secretary (Expenditure) ietrGnrlResearch012–560 Bangalore (JNCASR) Prof. R. Kumar* 26. 040–411 Pune Indian I 2 Rafi Marg, New Delhi – 110 001 ETH Research LaboratoryBhawan, Anusandhan Council of 1, Scientific & PhyreIndustrial Research Road, K.V. C Director General 001 Gurgaon– 122 Nainwal Mode, Manesar Near NSG Campus National Brain Research Centre President, NBRC Society ieCara University of Delhi South Campus, New Delhi –110 021 Benito Juarez Road, Ahmedabad – 380 015 Indian Institute of Management National Innovation Foundation Vice Chairman ars hna-0 3 4 Prof. Deepak Pental* 24. Mumbai – 400 01 Chennai-600 Madras, 036 Indian Institute of Technology Department of Electrical Engineering Professor od 0 3 UP)Chief Scientific Officer Dr. (Mrs.) Swati Piramal* 23. New Delhi –110 049 Noida – 201 031 (U.P.) Institutional Area 1-A, Sector 16-A (formerly M/s Vam Organics) Chairman il ru fCmaisNational Institute of Oceano Prakash Deep, 10 Birla Group of Companies Chairman 7, Tolstoy Marg Goa – 403 004403 – Goa New Delhi – 110 001 7, Tolstoy Marg Hyderabad – 500 007 (A.P.) Lodi Lodi Road, New Delhi – 11 Hyderabad – 500 007 (A.P.) th floor Dona Paula Dona floor 218 8 Dr. M.K. Bhan*28. 7 Prof. V.S. Ramamurthy*27. 25. Dr. Dr. Vijay Bhatkar*25. 2 Shri Ashok K. Puri22. Department of Biotechnology New New Delhi –110 016 Fellow Director Dr. Ambedkar Road, Parel Nicholas Piramal India Limited Bharat Heavy Electricals Limited Director nstitute of Science th Floor, CGO Complex 2 ampus 0 0 003 graphy nology, fic .D.HS igai Department of Ocean Development Dr. H.S. Singhania 2. .Dr. R.A. Mashelkar 1. 4. Dr. Vijay Bhatkar 11. Dr. Dr. Jitendra Bajaj 11. Secretary Dr. Vijay Bhatkar 4. Dr. Raju D. Shroff 3. .Po.VS aauty1.Dr. V.P. Dimri 14. Dr. T. Ramasami 13. Prof. V.S. Ramamurthy Director7. Prof. P. Balaram 6. Dr. Ashok Jhunjhunwala 5. JK Organisation, Nehru House Lodi Lodi Road JK Organisation, Nehru House 4, Bahadurshah Zafar Marg New New Delhi –110 003 New Delhi – 110 002 4, Bahadurshah Zafar Marg President Director General, CSIR 9. Dr. Dr. Harsh K. Gupta 9. Director General, CSIR Kendriya Vidyalaya Campus Mylapore, Mylapore, Chennai – 600 004 Centre for Research Policy S New Delhi –110 003 040– Pune411 Kendriya Vidyalaya Campus 1 Phyre Road, CGO Complex, Lodi RoETH DepartmentResearch Laboratory of Informa Chairman Mumbai – 400 052 United Phosphorus, Uniplus House Chairman and Managing Director Bangalore – 560 012 Lodi Lodi Road Block 2, 7-8 Floor, CGO Dr. M.K. Bhan 8. 012 – Bangalore560 Indian Institute of Science Director Chairman Prof. Goverdhan Mehta New Mehrauli Road Hyderabad – Hyderabad 500 007 Uppal Road 020 600 – Chennai National Geophysi Adyar New Delhi – 110 016 – Mysore 570 020 Central Leather Research I New Mehrauli Road Technology Bhavan Department of Science & Technology Secretary Institute 012 – Bangalore560 Indian Institute of Science Molecular CentralBiophysics FoodUnit Tec 020 600 Chennai– Indian Institute of Technology Professor of Information Technology MEMBERS OF ADVISORY BOARD OF ADVISORY MEMBERS (2002-2005) 219 0 Shri K.K. Jaswal 10. 12. Dr. Dr. V. Prakash12. Mahasagar Bhavan, CGO Complex Secretary 27, Rajsekharan Street Director New New Delhi –110 003 Department of Biotechnology Secretary Director hnological Research NEUE IV - ANNEXURE cal Research Institute, tion Technology Complex ad nstitute tudies
Annexures CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Annexures 0 Developing capabilities & facilities for Microel 20. Development of Key Technologies for Photonics and 19. 7 Animal models and animal substitute technologies 27. Drug target development using in-silico biology 26. Predictive medicine using repeat and single nucl 25. Setting up a world class drug research institute 24. Positioning Indian nutraceuticals and neutrigeno 23. Developing New Generation Fuels & Lubricants (II 22. Coal Characterisation & Resource Quality Assessm 21. .Exploration and Exploitation of Microbial Wealth Spearheading2. small civilian aircraft design, deve 1. 3 Toxicogenomics of polymorphism in Indian populati 13. Developing Cells & Tissue Engineering (CCMB) 12. Catering to Specialised Aerospace Materials (NAL) 11. Comprehensive Traditional Knowledge Digital Docu Environment10. friendly Leather Processing Technolog Special 9. Electron Tube Technologies for large scal Newer 8. scientific herbal preparations for global p Asthmatic 7. and allergic disorders mitigation missi Pollution6. monitoring mitigation systems and devic Study 5. of Mesozoic sediments for hydrocarbon explor Molecular4. biology of selected pathogens for devel 3. 8 Impact of anthropogenic perturbations oceanographi 18. Acquisition of Oceanographic Research Vessel (ORV 17. Developing Green Technologies for Organic Chemica 16. Development of Catalysis & Catalysts (NCL) 15. Designing animals and plants as bio-reactors for 14. around India in the context of global change (NIO) (CEERI) and biotransformation process (IMT) development of biomarkers (ITRC) IT F EWRE POET WT NDL LABS NODAL WITH PROJECTS NETWORKED OF LIST 220 ectrochemical systems (Mems) and Sensors (CDRI) (IGIB) eotide polymorphisms (IGIB) ositioning (RRL-JAMMU) proteins & other products (CIMAP) lopment & manufacture (NAL) e applications (CEERI ) oping drugs targets (CDRI ) mics mics in a global platform (CFTRI) on (IICB) of of India for novel compounds es es (NEERI ) (CDRI) P) ent (CFRI) y (CLRI ) Opto Electronics (CGCRI) ) for Oceanographic Research (NIO) mentation Library (NISCAIR ) ation (NGRI) ls (IICT) on to industrial chemicals for c c atmospheric Processes in and NEUE V - ANNEXURE 6 Globally competitive chemicals processes and produ 36. Medicinal plant chemotypes for enhanced marker a 35. High Science & Technology for National Aerospace 34. 8 Development of Techniques and Methodologies for 38. Development of Novel Polymeric Materials (NCL) 37. 3 Upgradation of SI Base Units, National Standards 33. Capacity building for Coastal placer mineral min 32. Custom tailored special materials (CGCRI) 31. Technologies for Standardization of Bioresources 30. Mathematical Modelling and Computer Simulation ( 29. Developing New Building Construction Materials ( 28. 0 Establishing Advanced facility for safety evalua 50. Establishing Genetically Modified Foods Referal 49. Consortium Access to Electronic Journals (NISCAI 48. National Science Digital Library (NSDL) (NISCAIR 47. New and Improved Road Technologies (CRRI) 46. Design analysis and health assessment of Special 45. Infectious diseases handling storage and Researc 44. Natural, nature identical or similar biomolecule 43. Coal Preparation for quality enhancement (CFRI) 42. Industrial Waste Minimization and Clean up (NEERI 41. Electronics for societal purposes (CSIO) 40. Tectonic and oceanic processes along Indian Ridg 39. 5 Discovery, Development and commercialization of 55. Technology for Engineering Critical Assessment ( 54. Developing capabilities in Advanced Manufacturin 53. 1 Developing technology packages for disaster preve 51. 2 Biomineral processing for extraction of metal va 52. Facilities (NPL) Management of Ground Water in hard rock areas (NGRI (RRL-BHUB.) drugs (CCMB) preparations (CSIRHQ.) coalifields (CMRI) 221 s (CFTRI) tion of genetically modified/engineered lues from ores and concentrates Facility (CFTRI) ing (CMRI) for and from Leather (CLRI ) h Facilities (CCMB) TECA) (NML) Structures Structures including bridges (SERC) e System and back arc basins (NIO) of of Measurements & Apex Calibration R) ) CBRI) programmes (NAL) ntion and management in underground nd value added compounds (CIMAP) g Technology (CMERI) New Bioactives and Traditional Exploration, Assessment and C-MMACS) cts ) [ ) (IICT)
Annexures CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Annexures EXTRACT OF CAG REPORT CAG OF EXTRACT Regional Research Laboratory (RRL), Thiruvananthapu The matter was referred to the Council in June 2004 have been avoided had the system been installed. 199liquid duringof nitrogen litres 10996 November than five years with possible implication on the ser Thus, the system procured at a cost of Rs 21.29 lakh enforcing the contract. not 'contain any arbitration clause in case of a di as of July 2004. It was further observed that the pu 2004 to persuade the firm for commissioning RRL took theup the matter syswith the High Commission of I nitrogen. The UK based firm refused in February 200 visit in August 2001. he found that though the syst chiller compressor were made defective by wrong ele compressor. He again checked the system in July 2001 April 2001 the agent could not install the system d The Indian agent tried to install the equipment in A accept the water cooling system supplied by the firm them. Thereafter, in a meeting with the Indian agen that they would supply the system as per order by Jan supply of the air-cooled system for which purchase ord responde RRL days. 90 of minimum a of delay also and destination which would be a complex situation and w offe agent the Alternatively, cost. of free chiller well to the specifications and their cost was almost suggested that the water cooling system behad happened this that system shippiand the at error operated placed for a system with air cooling facility, the The Indian agent of the firm informed RRL in Septemb August 1998. RRL paid Rs 21.29Iakh, for it including prod thefor lakh). equipment, required Rs The20.84 for the supply of a Nitrogen Generator and a liquefie of Scientific and Industrial Research, placed a purc 10.1 Unfruitful expenditure Unfruitful on expenditure procurement of Liquid 10.1 CHAPTER X: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RES INDUSTRIAL SCIENTIFIC AND OF COUNCIL X: CHAPTER last more than five years. was placed by RRL. The system has not been 'install the system with a water cooled facility instead of August 1998 at a cost of Rs21.29 lakh from a UK bas laboratory, Thiruvananthapuram procured one Nitroge 222 spute, spute, with the result that RRL had no means of system system that arrived at RRL was a water cooling red to get the air cooled system from another from system cooled air the get to red viceability of the equipment. RRL had procured tem, but the system had not been commissioned rchase order placed by RRL in March 1998 did , stressing that both the systems would perform em was working, it was not producing liquid ue to some problem in a cable connecting the pril, July and August 2001 without success. In hase order on a UK based firm in March 1998 , , 'who did not reply as of November 2004. t t of the firm held in May 2000, RRL agreed to the same. He also offered supplyto a water was lying uninstalled and unused for. more freight and bank charges in September 1998. r at a cost of UK Pound 28,600 (equivalent to . ctrical connections given by RRL. During his 2 2 to assist RRL in the matter any further. 8 to June 2003 at Rs 5.89 lakh Rs 5.89 June2003 whichcould 8 toat er 1998 that though the purchase order was and reported that the water pump and the uction of liquid nitrogen, was received in received uctionliquid was of nitrogen, ould involve additional shipping charges ng point IndianThe inthe agentfactory. uary the 2000, same was not supplied by ndia in London in October 2003 and June ram, ram, a constituent laboratory of Council er er was placed. Though the firm assured air cooling facility for which the order d in November 1998 insisting on theon insisting 1998 November in d Nitrogen ' pIant Regional Research: ed firm. However, the firm supplied ed so far and is lying unused for the n generator and one liquefier in NEUE VI - ANNEXURE EARCH doubt about the serviceability of the system as it it as system the of The matter was referred to serviceability the Council in the June 2004 about doubt of legal action against the firm. It further stated RRL stated in July 2004 that its vigilance had call initiated against the firm. co was theJuly as of system 2004,'neither However, of the firm for completion of the installation work the system. The Committee in December 2002 suggestemember Committee in September 2002 to suggest suitabIn view of the delay in installing/ commissioning o conditions the performance, amended bank not guarantee had clause. RRL as system the of 0.45 lakh which was received in April 2000. However, of more than six months, RRL in January 2000 placed firm who visited RRL in July 1999 could not install Transformer (CVT), it did not arrange for the same other charges in the same month. Though RRL was awa expenditure of Rs 13.08 lakh. Absence of the system system the of lakh.Absence 13.08 Rs of expenditure eve system the of installation ensure to failed RRL been possible to conduct larger scale fermentation. Industrial Research, placed an order in March 1999 a 1999 March in order an placed Research, Industrial Bhubaneshwa (RRL), Laboratory Research Regional The Non-installation of Fermentation System10.2 a clause for performance bank guarantee of 10 10 of guarantee bank performance for clause a March 1999, RRL incorporated a guarantee clause for from the date of commissioning/ demonstration which had offered guarantee for a period of 14 months from The order was placed on the basis of quotation recei the area of larger scale fermentation studies for b 100 litres capacity non-cycling batch type fermentor Kolkata, for supply of fermentation system comprising guarantee. Immediately after receipt of the order, system in June 1999. RRL released Rs 13.08 1akh. 1akh. wh system inRs 13.08 Junereleased RRL 1999. members which went for inspection that the amendment for inspection and found the fermentor ready for dis respond to the firm' s request. In May 1999 the a two-mterms and conditions of the purchase order. whi years. the system which was procured at a cost of Rs 13.08 their confirmation. As a result, the firm refused t order while placing for the procurement of a Fermen termsLaboratory and Regional the amended Research that due to non-installation of the system it had 223 ed for the documents for examination for initiation per centper io-fuel application. the system in the absence of CVT. After a lapse ember team of RRL visited the works of the firm the firm in April 1999 requested RRL to amend f the system, Director, RRL constituted a three'- ch were not as per their quotation. RRL did not , , failing which legal action could be initiated. . . The system was required to build capacity in . who did not reply as of November 2004. ved in December 1998 from the firm. The firm before before installation. The representative of the an order for procurement of CVT costing Rs the firm refused to complete the installation the date of delivery/dispatch or 12 months mmissionedany nor beenactionlegal had patch. patch. On the assurance given by the team d. to give a final chance to the representative a period of 24 months and also introduced atr ie er ad fe icrig an incurring after and years five after n ich was 90 ich was re of the requirement of a Constant Voltage ever was earlier. While placing the order in hampered research. There is also seriousalso is There research. hampered 50 litres capacity recycling fermentor and le measures to expedite the'" installation of t a cost of Rs 13 lakh on a firm based at based firm a on lakh 13 Rs of cost a t o complete the installation, resulting in of the order value during the period of period the valueduring order the of a be lig nntle fr long. for uninstalled lying been has would be issued, the firm delivered the lakh lying unused for more than four r, a unit of Council of Scientific and Scientific of Council of unit a r, f h prhs odr eeig the deleting order purchase the of tation tation obtainingSystem without conditions quoted by the the firm by quoted conditions per cent of the order value plusof the order n o t
Annexures CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Annexures July July 26, 2004 New Delhi Distinguished Members of the CSIR Society, Ladies a .It gives me great pleasure to be with you at this 1. .I will be seeking your advice and support with res 2. .I would likethe congratulate remarka to CSIR for 3. 4. CSIR is very fortunate to have Shri Kapil Sibal as Sibal Kapil Shri have to fortunate very is CSIR 4. .I am happy to see that CSIR is flying higher and 5. .This CSIR Society meeting is taking place almost t 6. areas will remain subjects of high priority for me industrial research in our country. I would like to I have taken keen interest in the development of sci for achieving this feat. It is particularly gratify driven and user focused organistion. The entire CSI the Kelkar Committee that was set up for the purpose CSIR’s next phase of transformation will be driven international management experts on this transforma th business, the from received has it accolades the ideas that we should give high priority to. area of science and technology and would appreciate wishes for a glorious journey ahead for the CSIR fa foreseeable As future. the President of CSIR Societ am sure the process of the next phase of transformat Technology and also as the Vice-President of CSIR. aircrafts world over. industry in GoingIndia. I further, hope would SARAS also Ilarge. the benefit SARAS country am at sure technological prowess to create products that will b SARAS feat. to me is just not itan is aaircraft, indigenously designed and built by our own scientis news of the successful maiden flight of SARAS on 29 make a greater difference to the lives of the India begin by emphasizing the new direction that science science and technology has been given a place of pri Programme (CMP) annou of the United already Progressive Alliance has Government The place. in been has Prime Minister's Speech Prime at Minister's Speech the CSIRMeeting Society 224 nd Gentlemen. ing to see, from Dr. Mashelkar’s presentation, meeting of the Society. As many of you know, symbol of determination India’s to use its further. I was particularly happy to get the n people. and and our government. reassure you at the very outset that these by the recommendations made thorough hree hree months after our new Government pect pect to policies and programmes in the mily. ion of CSIR will be completed within the ble transformation bleinto transformation a performance e not only globally competitive but will y, y, I would like to extend my very best andScience for State of Minister the th May, this year. This aircraft has been R family deserves to be complimented will herald thewillcivil dawn herald aviation of and technology has to take in future to ts ts and engineers. We are proud of this e scientific community, and also the also and community, scientific e Knowing his dynamism and vision, I de de in this programme. I would like to ence & technology and scientific and . tion. I am also happy to hear that the your coming forward with practical on on 27th May, 2004. As you will see, become a ‘brand ‘brand name’ for become smalla cd h Cmo Minimum Common the nced NEUE VII - ANNEXURE 1 Water is becoming a precious commodity. I unders 11. 9. Let Let us take a special issue of the disease burden 9. 0 CSIR could do a lot in other sectors too. For e 10. .Our S&T system can play a decisive role only whe 8. .CMP envisages that the UPA Government will follow 7. just a selected few. A theme that is close to my he the weaker sections in rural areas. Can we look at so so that such tragedies do not occur. happening around, such as in Kumbakonam, and respond Navodaya Vidyalaya in the past. However, I would li and affordable at the same time? I am familiar with alternative technologies that will create safer fir around 100 young children perished in Kumbakonam in affordable housing for the poor? We have just witnes overall quality of life? ameliorate the poverty, create jobs, remove the dis poor and the In underprivileged’. can we other words, of society, not just a privileged few. It must play diseases of the poor. end this in industry Indian with partner active and put pressure on the Indian drug industry to develop n process chemistry but development of entirely new dr including, Malaria, etc. AIDS, It should continue i developin of record track a had has CSIR development. must India therefore, and, soaring been have drugs reasonable prices. As was pointed out by Dr. Mashel a ensure to steps all take will Government UPA that ‘global leadership’ but also on issues which have de Dr. Mashelkar’s presentation that CSIR’s programmes areas covering both ‘global leadership’ and ‘local t that science and technology development and applicati that will strengthen India’s vast science and techn with other Ministries and Departments. without achieved Technologists be can must integrate nothing but their efforts much fully so in do can in new technologies to fulfil this mission? I amwomen ac carrying water over a distance of a few kilomfulfilling from away far are we However, objective. drinking water to 186000 villages in India’. Rajiv Kennedy set up a mission to send a man on the Scientific moon. Advisory Committee to Prime Minister (SA 225 xample, CMP has focused on the housing for the bigger role of creating wealth for all, not utely aware of the fact that new technologies e proof structures, which are cost effective to such delivery mechanisms by partnering art is on ‘making technologies work for the of of the poor. We have emphasized in CMP ology infrastructure. We have also stressed Gandhi Mission was set up to achieve this n it advances the well being of all sections ease burden of the poor, and improve the the use of new technologies for creating ts ts efforts further not only on innovative tand that in one of the early ransformation’. I am happy to see from the policies and introduce programmes the good work that CSIR had done in eters is still common. Can we not bring To me the equivalent mission is to take ep ‘local relevance’. ke to see a CSIR that is sensitive to the kar, kar, the costs of development of new this dream of Rajivji. The scenes of scenes The Rajivji. of dream this sed sed the heart rendering scenes when eavour and especially focus on theon focus especially and eavour C-PM), C-PM), Rajiv Gandhi had said ‘John find out alternative paths for drug for paths alternative out find ugs. The new IPR regime is going to ew drugs. CSIR should be a willing on missions will be launched in key have focused on not only attaining vailability of life saving drugs at drugs saving life of vailability develop technologies, which will g drugs for diseases of the poorthe of diseases for drugs g Tamil Nadu. Can we not look at with speed and determination od eiey mechanisms. delivery good meetings of
Annexures CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Annexures Thank you I wish the society well in its work. 5 There is a new big opportunity in terms of the he 15. 7 The Government will not shy away from investing 17. It was Pandit Jawaharlal Nehru, who had realized 16. 4 I had also said that decentralized power in term 14. 12. Several Several of CSIR’s core competencies can be used e 12. 3 hl adesn te ofrne f he Ministe Chief of conference the addressing While 13. competitive. country move self-reliant. Equally our focus must b development provided what we do improves the qualit achieve this objective. viable economic option. CSIR should develop and deli make the Gandhian vision of decentralized production can bring in a new societal transformation. to the creation of economic wealth for the people. C this approach. Here is a possibility of the herbal we India’s herbal wealth has demonstrated that value a ‘bioactives CSIR’s on presentation Mashelkar’s Dr. can greatly benefit from the attention now given by technology being provided by CSIR. giving them fullof technologicalcredit and market to decided have We industry. scale in small schemes small businesses need to be fully harnessed. We wan break possibilities grounds newin to proincreasing activiti allied its and agriculture our of potential fashi be must development rural the for strategy our throughprosperity Panchayat Raj that heldwas on 29t great march of science is supported most enthusiast Society that this Government we will do its best to I mankind’swish enterprise today’. greatest ass to m the in fully participate to heritage cultural great of a great country like India with its traditions o in nation building in post-independent India. He had targets set up in CMP. technologicapossibleall provide to fashion India’ l wouldI technologies. desalinationin expertise of along the Coromandel Coast starting with Chennai. I Theproblems. its Government has declared intention 226 s s of local electricity generation and use can rbal wealth of people in tribal areas, which f f scholarship and original thinking and its the crucial role of science and technology business to Non Timber Wood Products. ffectively to solve India’s water related see that the Indian participation in this e on making our industry more globally alth of the people in tribal areas leading dded therapeutics can be made through SIR needs to redouble this effort, which in science and technology research and l assistance so that we can meet these meet can we that so assistance l ure the eminent members of the CSIR s I a srse ta technological that stressed had I es. ically and vigorously. ike to see CSIR work in a true ‘Team true ain work CSIR see to ike ing I would support. kike to see such understand that CSIR has a great deal s n oet alvain n rural and alleviation poverty on rs once said ‘it is an inherent obligation ductive capacity of small farms of farms andsmall capacity ductive network programme’ by exploitingby programme’ network rh fsine wihi probably is which science, of arch t to t focus on employment intensive ver such technologies so that we can free this sector from Inspector Raj Inspector from sector this free y of life of our people and makes our to to establish desalination plants all oned to unleash the productivitythe unleash to oned h June, I2004, had suggested that not only an ethical idea but also a The speech by MOS (IC) (S&T & OD) on 26th July, 200 4. The exemplary leadership provided by Dr. Mashelkar Dr. by provided leadership exemplary The 4. .Hon’ble Prime Minister, a warm welcome to you. It 1. .Over the last two months, we have introspected. We 5. 3. I am proud and fortune to be the Vice-President o Vice-President the be to fortune and proud am I 3. g my to welcome warm a extend to like also will I 2. contribute to the CMP. On 20th and 21st August, I a the CSIR family. Each CSIR laboratory has had detai for CSIR, but what we in CSIR can do for the nation about the future of CSIR. responsibilit their view family the of members which notice happy unique am to this I of family. members Mashelkar and his team closely. I have been visitin rural poor. communication with the people. We must communicate b press not just to inform but also be open to public developmental goals that we are committed to realis CSIR's achievements but the contributions of the sc CSIR’s proud Vice-President, I would like to communOne of our first endeavours, therefore, is to make was developed by NPL. All this represents pathbreakin million voters receive indelible ink marks, they ha printing technique, little does one realise that it does not realise the role of CDRI. When a paternity CFTRI. When a prescribes doctor to E-MAL a patient kno not she does child, to her Amul babygives food Swaraj or Sonalika tractor, he does not know that i co extraordinary this of aware be not is man common unique entity that is truly making a difference to aspirations of the people of India. guidancethe CSIR We family. to would likethe CSIR stands for. You have given the common man hope for Minimum of Thethe good Program. mancommon is cent been in power, you have set new paradigms - President of the CSIR giving InSociety. the short span of Minister, Mr. Chidambaram. I also welcome all the e CSIR Society CSIR MeetingSociety 227 was pioneered in India by CCMB. When 650 4 people aware of what CSIR is all about. As audit. We will also explore other means of the lives of ordinary Indians. Perhaps the is a matter of pride for us that you are the t is designed by CMERI. When a mother rdly rdly realise that the original technology g CSIR laboratories and meeting young . . The CMP has been studied in depth by India a new vision through the Common nd all the Directors of CSIR are meeting dispute is solved by using DNA finger two months two thisthat hasGovernment ientific fraternity in my Ministry to the f CSIR. I have been working with Dr.with been workinghave I CSIR. f icate with people - not only to showcase minent members of the Society. e. e. That is why every month, I meet the are not asking what the nation can do ood friend and the Hon’ble FinanceHon’ble the and friend ood led led brain storming to see what it can w that the product is developed by is developed product that the w the future. We look forward to your suffering from cerebral Malaria, he to be instrumentalto inrealizing the the commitment and passion withpassion and the commitment ies. This makes me feel optimisticfeel me makes This ies. g activities of CSIR laboratories. ntribution. When a farmer uses auses farmer a When ntribution. has transformed the CSIR into ainto CSIR the transformed has oth with the urban elite and the ral to all our ral to that Government
Annexures CSIR Annual Report 2004-05 CSIR Annual Report 2004-05 Annexures .I once again thank the Hon'ble Prime Minister for 9. real its achieve to has yet CSIR that believe We 7. .CSIR's transformation in the decade of nineties i 6. .Finally, let me recollect with pride the maiden f 8. activities will kindle hope in future generations. Dr. Mashelkar to make his presentation on the ongoi others. mitigate the distress of farmers by forgingSwaminathan. Dr. with a discussion a partnhad haveI that. CSIR. We will be delighted to help, of course, in e him reform and restructure, revitalise ICAR by usin Sharad Pawer has been having consultations with som presentation will give you a glimpse of this. Recentl intend to help and guide CSIR to implement the Kelk would propel CSIR to become a vibrant prime mover of t and encouraging. Many of its are recommendations to report. A presentation was made to me by the Kelkar economists, scientists and administrators as its me attempted to address this question by setting up a 2004. The entire nation was proud of 'TEAM SARAS'. T present to our Hon'ble Prime Minister. lined up a few major initiatives with detailed imple complementary strengths in desalination technology. have had several meetings to make a technology offe around the Coromandel Coast. Bhabha desal Atomicup setting of intention the announcedResearch CMP, the will be a 'Team India' effort. Let me cite one exam health, energy, environment, housing and so on. It in Bangalore to draw out a detailed plan on what CS 228 light of SARAS that took place on 29th May s s admired worldwide. Dr. Mashelkar in his ership between ICAR, CSIR, DST, DBT and Committee under Dr. Kelkar, with eminent very possible way. But we will go beyond his gracious presence today. I now invite ple. Our FM, following the declaration in potential. We must do that quickly. We quickly. that do must We potential. mbers. The Committee has submitted its will not only be a 'Team CSIR' effort - it ng journey of the CSIR. I believe that its mentation plans that we would like to y, my friend and senior colleague, Mr. ar Committee report . ring to fulfill this objective - both have g our own successful experiments in IR IR can do in critical of sectors water, Committee. It findings are revealing By the end of August, we will have We are now working on a plan toplan aon working now are We Centre (BARC) and CSIR's CSMCRI e of us to see as to how we can help hey deserve our congratulations. pical, pical, timely ifand, implemented, ination plants for drinking waterdrinking for plants ination he National Innovation system. I CSIR ESTABLISHMENTS
CBRI Central Building Research Institute, Roorkee -247 667 CCMB Centre for Cellular and Molecular Biology, Hyderabad-500 007 CDRI Central Drug Research Institute, Lucknow -226 001, cdriindia.org CECRI Central Electrochemical Research Institute, Karaikudi -623 006 CEERI Central Electronics Engineering Research Institute, Pilani -333 031 CFRI Central Fuel Research Institute, Dhanbad -828 108 CFTRI Central Food Technological Research Institute, Mysore-570 020 CGCRI Central Glass and Ceramic Research Institute, Kolkata -700 032 CIMAP Central Institute of Medicinal & Aromatic Plants, Lucknow -226 015 CLRI Central Leather Research Institute, Madras -600 020 CMERI Central Mechanical Engineering Research Institute, Durgapur -713 209 CMRI Central Mining Research Institute, Dhanbad -826 001 CRRI Central Road Research Institute, New Delhi -110 020 CSIO Central Scientific Instruments Organisation, Chandigarh -160 030, CSMCRI Central Salt & Marine Chemicals Research Institute, Bhavnagar -364 002, IGIB Institute of Genomics & Integrative Biology, Delhi -110 007 IHBT Institute of Himalayan Bioresource Technology, Palampur -176 061 (HP), IICB Indian Institute of Chemical Biology Jadavpur, Calcutta -700 032 IICT Indian Institute of Chemical Technology, Hyderabad -500 007 IIP Indian Institute of Petroleum, Dehradun -248 005 IMT Institute of Microbial Technology, Chandigarh -160 036 ITRC Industrial Toxicology Research Centre, Lucknow -226 001 NAL National Aerospace Laboratories Bangalore -560 017 NBRI National Botanical Research Institute, Lucknow -226 001 NCL National Chemical Laboratory, Pune -411 008 NEERI National Environmental Engineering Resarch Institute, Nagpur -440 020 NGRI National Geophysical Research Institute, Hyderabad -500 007 NIO National Institute of Oceanography, Goa -403 004 NISCAIR National Institute of Science Communication And Information Resources , New Delhi-110012 NISTADS National Institute of Science Technology and Development Studies, New Delhi-110012 NML National Metallurgical Laboratory, Jamshedpur-831 007 NPL National Physical Laboratory, New Delhi -110 012 RRL-BHO Regional Research Laboratory, Bhopal -462 026 RRL-BHU Regional Research Laboratory, Bhubaneshwar -751 013 RRL-JAM Regional Research Laboratory, Jammu Tawi -180 001 RRL-JOR Regional Research Laboratory, Jorhat -785 006 RRL-TRI Regional Research Laboratory, Thiruvananthapuram -695 019 SERC Structural Engineering Research Centre, Chennai -600 113