Table S1 (Goes with Figure 1)

Table S1. SigClust classification of 56 Trp53 null mouse mammary tumors. GSE# SigClust Result Host-IR Status Genotype GSM691237.CEL Basal-like IR-host WT GSM691250.CEL Basal-like IR-host WT GSM691236.CEL Claudin-low IR-host WT GSM691241.CEL Claudin-low IR-host WT GSM691256.CEL Claudin-low IR-host WT GSM691257.CEL Claudin-low IR-host WT GSM691247.CEL p53 null IR-host WT GSM691254.CEL p53 null IR-host WT GSM691246. CEL UlUnclass ifidified-1 IR-hthost WT GSM691249.CEL Unclassified-1 IR-host WT GSM691251.CEL Unclassified-1 IR-host WT GSM691253.CEL Unclassified-1 IR-host WT GSM691255.CEL Unclassified-1 IR-host WT GSM691235.CEL Luminal IR-host WT GSM691238.CEL Luminal IR-host WT GSM691239.CEL Luminal IR-host WT GSM691242.CEL Luminal IR-host WT GSM691243. CEL Luminal IR-host WT GSM691244.CEL Luminal IR-host WT GSM691245.CEL Luminal IR-host WT GSM691248.CEL Luminal IR-host WT GSM691252.CEL Luminal IR-host WT GSM691240.CEL Unclassified-2 IR-host WT GSM691228.CEL Basal-like Sham WT GSM691229.CEL Claudin-low Sham WT GSM691230.CEL Claudin-low Sham WT GSM691231.CEL Claudin-low Sham WT GSM691226.CEL Luminal Sham WT GSM691227.CEL Luminal Sham WT GSM691233.CEL Luminal Sham WT GSM691234.CEL Luminal Sham WT GSM691232.CEL Unclassified-2 Sham WT David.N.4.Het.122110.CEL Claudin-low IR-host TGFb +/- GSM691272.CEL Claudin-low IR-host TGFb +/- GSM691274.CEL Claudin-low IR-host TGFb +/- GSM691275.CEL Claudin-low IR-host TGFb +/- GSM691276.CEL Claudin-low IR-host TGFb +/- David.N.1.Het.122110.CEL p53 null IR-host TGFb +/- David.N.49.Het.122110.CEL p53 null IR-host TGFb +/- David.N.50.Het.122110.CEL p53 null IR-host TGFb +/- David.N.47.Het.122110.CEL Unclassified-1 IR-host TGFb +/- David.N.55.Het.122110.CEL Unclassified-1 IR-host TGFb +/- GSM691279.CEL Unclassified-1 IR-host TGFb +/- David.N.26.Het.122110.CEL Luminal IR-host TGFb +/- David.N.35.Het.122110.CEL Luminal IR-host TGFb +/- GSM691273.CEL Luminal IR-host TGFb +/- GSM691278.CEL Luminal IR-host TGFb +/- GSM691280.CEL Luminal IR-host TGFb +/- GSM691277.CEL Unclassified-2 IR-host TGFb +/- GSM691281.CEL Unclassified-2 IR-host TGFb +/- GSM691258.CEL Basal-like Sham TGFb +/- GSM691262.CEL Basal-like Sham TGFb +/- GSM691259.CEL Claudin-low Sham TGFb +/- GSM691263.CEL Claudin-low Sham TGFb +/- GSM691261. CEL p53 null Sham TGFb + /- GSM691260.CEL Luminal Sham TGFb +/- Table S2 (Goes with Figure 2). Genes in the 323-irradiated host signature

Affy Probe Symbol Direction Affy Probe Symbol Direction Affy Probe Symbol Direction Affy Probe Symbol Direction Affy Probe Symbol Direction 1456878_at AI646023 UP 1427285_s_at Malat1 UP 1423523_at Aass DOWN 1456741_s_at Gpm6a DOWN 1454934_at Ppm1f DOWN 1453239_a_at Ankrd22 UP 1431385_a_at Mbtps1 UP 1425032_at Abpb DOWN 1455466_at Gpr133 DOWN 1457029_at Ppp4r1l DOWN 1432344_a_at Aplp2 UP 1419504_at Mogat1 UP 1418754_at Adcy8 DOWN 1424613_at Gprc5b DOWN 1429463_at Prkaa2 DOWN 1417561_at Apoc1 UP 1451858_at Mrgpra2 UP 1424393_s_at Adhfe1 DOWN 1416411_at Gstm2 DOWN 1418666_at Ptx3 DOWN 1418687_at Arc UP 1426941_at Muc15 UP 1447839_x_at Adm DOWN 1417883_at Gstt2 DOWN 1417741_at Pygl DOWN AU02009 1455172_at 4 UP 1438730_at Nav1 UP 1419706_a_at Akap12 DOWN 1420872_at Gucy1b3 DOWN 1434914_at Rab6b DOWN 1423456_at Bzw2 UP 1435981_at Nav2 UP 1451675_a_at Alas2 DOWN 1440145_at H60a DOWN 1420603_s_at Raet1a DOWN 1443227_at Bzw2 UP 1447885_x_at Nedd9 UP 1438967_x_at Amhr2 DOWN 1452145_at H6pd DOWN 1455840_at Rapgef5 DOWN 1426043_a_at Capn3 UP 1453614_a_at Nfe2l3 UP 1453287_at Ankrd33b DOWN 1418645_at Hal DOWN 1437902_s_at Rarres2 DOWN 1421952_at Capn6 UP 1435486_at Pak3 UP 1432006_at Ap2a2 DOWN 1420589_at Has3 DOWN 1449461_at Rbp7 DOWN 1428735_at Cd69 UP 1437318_at Pak3 UP 1416371_at Apod DOWN 1417714_x_at Hba-a1 DOWN 1424382_at Rcn3 DOWN 1455435_s_at Chdh UP 1436124_at Pcyt1b UP 1435050_at Arfgef3 DOWN 1417184_s_at Hbb-b1 DOWN 1415905_at Reg1 DOWN 1437578_at Clca2 UP 1418210_at Pfn2 UP 1441618_at Arhgap29 DOWN 1451229_at Hdac11 DOWN 1418003_at Rgc32 DOWN 1419463_at Clca2 UP 1449374_at Pipox UP 1452303_at Arhgef10 DOWN 1448239_at Hmox1 DOWN 1450693_at Rgs17 DOWN 1435504_at Clip4 UP 1449586_at Pkp1 UP 1460346_at Arsa DOWN 1424367_a_at Homer2 DOWN 1452899_at Rian DOWN 1425476_at Col4a5 UP 1448558_a_at Pla2g4a UP 1452308_a_at Atp1a2 DOWN 1457671_at Homer2 DOWN 1436044_at Scn7a DOWN 1417497_at Cp UP 1430700_a_at Pla2g7 UP 1448211_at Atp6v0e2 DOWN 1452388_at Hspa1a DOWN 1417580_s_at Selenbp1 DOWN 1455579_at Csn1s2a UP 1418203_at Pmaip1 UP 1440293_at C230081A13Rik DOWN 1422196_at Htr5b DOWN 1420558_at Selp DOWN 1420369_a_at Csn2 UP 1447623_s_at Prkd1 UP 1427355_at Calca DOWN 1425324_x_at Igh DOWN 1429459_at Sema3d DOWN 1419697_at Cxcl11 UP 1420352_at Prss22 UP 1422639_at Calcb DOWN 1437876_at Il20rb DOWN 1439768_x_at Sema4f DOWN 1418652_at Cxcl9 UP 1419669_at Prtn3 UP 1424770_at Cald1 DOWN 1450297_at Il6 DOWN 1419100_at Serpina3n DOWN 1454106_a_at Cxxc1 UP 1449310_at Ptger2 UP 1418509_at Cbr2 DOWN 1436755_at Itih5 DOWN 1419082_at Serpinb2 DOWN 1436345_at D1Mgi54 UP 1421073_a_at Ptger4 UP 1420380_at Ccl2 DOWN 1423180_at Kcnb1 DOWN 1419149_at Serpine1 DOWN 1435940_at Dclk1 UP 1419229_at Rhox4a UP 1417266_at Ccl6 DOWN 1454701_at Lars DOWN 1416702_at Serpini1 DOWN 1426005_at Dmp1 UP 1455347_at Rtel1 UP 1419684_at Ccl8 DOWN 1456156_at Lepr DOWN 1438042_at Shox2 DOWN 1458000_at Dsg1a UP 1424704_at Runx2 UP 1419144_at Cd163 DOWN 1425644_at Lepr DOWN 1426550_at Sidt1 DOWN 1415857_at Emb UP 1417719_at Sap30 UP 1449918_at Cd209g DOWN 1440147_at Lgi2 DOWN 1419437_at Sim2 DOWN 1425272_at Emp2 UP 1459897_a_at Sbsn UP 1423166_at Cd36 DOWN 1435321_at Limch1 DOWN 1417623_at Slc12a2 DOWN 1433670_at Emp2 UP 1420764_at Scrg1 UP 1450884_at Cd36 DOWN 1435106_at Limch1 DOWN 1448780_at Slc12a2 DOWN 1442542_at Eya4 UP 1450734_at Sec16b UP 1432022_at Cdgap DOWN 1424596_s_at Lmcd1 DOWN 1420334_at Slc12a8 DOWN 1419490_at Fam19a5 UP 1425002_at Sectm1a UP 1450140_a_at Cdkn2a DOWN 1456909_at LOC676974 DOWN 1418395_at Slc47a1 DOWN 1436576_at Fam26f UP 1419478_at Sectm1b UP 1452309_at Cgnl1 DOWN 1433536_at Lrp11 DOWN 1420504_at Slc6a14 DOWN 1429682_at Fam46c UP 1441941_x_at Serpinb5 UP 1433720_s_at Chchd10 DOWN 1418061_at Ltbp2 DOWN 1433933_s_at Slco2b1 DOWN 1418596_at Fgfr4 UP 1420378_at Sftpd UP 1454866_s_at Clic6 DOWN 1429379_at Lyve1 DOWN 1418493_a_at Snca DOWN 1438558_x_at Foxq1 UP 1423024_at Sh2d1b1 UP 1449456_a_at Cma1 DOWN 1449283_a_at Mapk12 DOWN 1416967_at Sox2 DOWN 1422735_at Foxq1 UP 1422856_at Slc12a3 UP 1448730_at Cpa3 DOWN 1434140_at Mcf2l DOWN 1458203_at Spire1 DOWN G530011 1440342_at O06Rik UP 1427339_at Slc30a2 UP 1416194_at Cyp4b1 DOWN 1449989_at Mcpt2 DOWN 1452604_at Stard13 DOWN 1418776_at Gbp8 UP 1460541_at Slc7a6 UP 1458934_at D5Ertd505e DOWN 1427040_at Mdfic DOWN 1430165_at Stk17b DOWN 1439015_at Gfra1 UP 1449340_at Sostdc1 UP 1418174_at Dbp DOWN 1452905_at Meg3 DOWN 1423280_at Stmn2 DOWN 1448485_at Ggt1 UP 1435438_at Sox8 UP 1429298_at Ddah1 DOWN 1455531_at Mfsd4 DOWN 1455610_at Synm DOWN 1416715_at Gjb3 UP 1423323_at Tacstd2 UP 1436661_at Dpp10 DOWN 1436021_at Mfsd4 DOWN 1418107_at Tcea2 DOWN 1422179_at Gjb4 UP 1422188_s_at Tcrg-V2 UP 1436479_a_at Dpp7 DOWN 1424123_at Mfsd7c DOWN 1423340_at Tcfap2b DOWN 1424927_at Glipr1 UP 1448069_at Tm4sf1 UP 1421276_a_at Dst DOWN 1419605_at Mgl1 DOWN 1419537_at Tcfec DOWN 1424825_a_at Glycam1 UP 1449033_at Tnfrsf11b UP 1422411_s_at Ear1 DOWN 1421977_at Mmp19 DOWN 1420191_s_at Tmem191c DOWN 1457227_at Gm11266 UP 1418309_at Tnfrsf11b UP 1425295_at Ear11 DOWN 1450430_at Mrc1 DOWN 1435261_at Tmtc1 DOWN 1449009_at Gm12185 UP 1422740_at Tnfrsf21 UP 1417236_at Ehd3 DOWN 1432205_a_at Mtus2 DOWN 1450798_at Tnxb DOWN 1447870_x_at Gm2292 UP 1439680_at Tnfsf10 UP 1427484_at Eml5 DOWN 1424933_at Myo5c DOWN 1426175_a_at Tpsab1 DOWN 1452353_at Gpr155 UP 1418158_at Trp63 UP 1418829_a_at Eno2 DOWN 1421385_a_at Myo7a DOWN 1420772_a_at Tsc22d3 DOWN 1430332_a_at Gusb UP 1455377_at Ttll7 UP 1449324_at Ero1l DOWN 1447271_at Nck1 DOWN 1424649_a_at Tspan8 DOWN 1443783_x_at H2-Aa UP 1429946_at Ttn UP 1455267_at Esrrg DOWN 1422520_at Nefm DOWN 1419584_at Ttc28 DOWN 1418536_at H2-Q7 UP 1423719_at U46068 UP 1433514_at Etnk1 DOWN 1446990_at Nfia DOWN 1448260_at Uchl1 DOWN 1442130_at Hsh2d UP 1421694_a_at Vcan UP 1448876_at Evc DOWN 1456087_at Nfia DOWN 1451651_at Vsig4 DOWN 1438441_at Id4 UP 1418175_at Vdr UP 1448929_at F13a1 DOWN 1432517_a_at Nnmt DOWN 1437556_at Zfhx4 DOWN 1423260_at Id4 UP 1460657_at Wnt10a UP 1443904_at Fads6 DOWN 1435184_at Npr3 DOWN 1455786_at Zfp820 DOWN 1454159_a_at Igfbp2 UP 1457499_at Wwp2 UP 1438402_at Fam171a1 DOWN 1418157_at Nr2f1 DOWN 1449314_at Zfpm2 DOWN 1455048_at Igsf3 UP 1436365_at Zbtb7c UP 1416978_at Fcgrt DOWN 1438448_at Otop1 DOWN 1428812_at 1700040L02Rik DOWN 1421628_at Il18r1 UP 1430674_at 1700016C15Rik UP 1418243_at Fcna DOWN 1426259_at Pank3 DOWN 1429203_at 2410076I21Rik DOWN 1421304_at Klra2 UP 1436431_at 1700025G04Rik UP 1449555_a_at Fetub DOWN 1417273_at Pdk4 DOWN 1430823_at 2700029L08Rik DOWN 1427352_at Krt79 UP 1425233_at 2210407C18Rik UP 1420086_x_at Fgf4 DOWN 1435553_at Pdzd2 DOWN 1433320_at 4930519N06Rik DOWN 1417812_a_at Lamb3 UP 1419643_s_at 2310057J18Rik UP 1435459_at Fmo2 DOWN 1448995_at Pf4 DOWN 1442113_at 5330417C22Rik DOWN 1433783_at Ldb3 UP 1453261_at 2610035D17Rik UP 1451648_a_at Folr2 DOWN 1418471_at Pgf DOWN 1441799_at 6030422H21Rik DOWN 1430551_s_at Lipm UP 1430162_at 3830417A13Rik UP 1438232_at Foxp2 DOWN 1438774_s_at Pgm2l1 DOWN 1433837_at 8430408G22Rik DOWN 1418723_at Lpar3 UP 1431577_at 5430437J10Rik UP 1426594_at Frmd4b DOWN 1435771_at Plcb4 DOWN 1459344_at 9630019E01Rik DOWN 1417942_at Lypd3 UP 1427521_a_at 9930023K05Rik UP 1438169_a_at Frmd4b DOWN 1456369_at Pot1a DOWN 1454855_at Magi2 UP 1442011_at A230065H16Rik UP 1429236_at Galntl2 DOWN 1418480_at Ppbp DOWN Figure S1 (Goes with Figure 2)

Figure S1. The irradiated host signature detects radiation-preceded human cancers. (A) Mammary tumors arising in sham or irradiated rats or (B) medulobastomas arising in sham or irradiated Ptch1 mutant mice clustered using the irradiated host signature.

Sporadic IR-preceded

A B Table S3 (Goes with Figure 3). Genes of the 72-gene centroid

AffyProbe GeneSymbol EntrezGene AffyProbe GeneSymbol EntrezGene 1418687_at Arc 11838 1418652_at Cxcl9 17329 1418107_at Tcea2 21400 1417812_a_at Lamb3 16780 1432006_at Ap2a2 11772 1419149_at Serpine1 18787 1421276_a_at Dst 13518 1449310_at Ptger2 19217 1425272_at Emp2 13731 1432344_a_at Aplp2 11804 1421952_at Capn6 12338 1448876_at Evc 59056 1417741_at Pygl 110095 1426043_a_at Capn3 12335 1448558_a_at Pla2g4a 18783 1418003_at 1190002H23Rik 66214 1448929_at F13a1 74145 1451675_a_at Alas2 11656 1452145_at H6pd 100198 1418210_at Pfn2 18645 1449324_at Ero1l 50527 1435981_at Nav2 78286 1417719_at Sap30 60406 1418471_at Pgf 18654 1421073_a_at Ptger4 19219 1421628_at Il18r1 16182 1424927_at Glipr1 73690 1431385_a_at Mbtps1 56453 1421385_a_at Myo7a 17921 1460541_at Slc7a6 330836 1454159_a_at Igfbp2 16008 1419706_a_at Akap12 83397 1452604_ at Stard13 243362 1429379_ at Lyve1 114332 1426594_at Frmd4b 232288 1419100_at Serpina3n 20716 1420772_a_at Tsc22d3 14605 1418203_at Pmaip1 58801 1417883_at Gstt2 14872 1419584_at Ttc28 209683 1418645_at Hal 15109 1416978_at Fcgrt 14132 1418061_at Ltbp2 16997 1418493_a_at Snca 20617 1426259_at Pank3 211347 1418158_at Trp63 22061 1423166_at Cd36 12491 1452388_at Hspa1a 193740 1418829__ a at Eno2 13807 1420764_ at Scrg1 20284 1424596_s_at Lmcd1 30937 1424367_a_at Homer2 26557 1451648_a_at Folr2 14276 1417623_at Slc12a2 20496 1448211_at Atp6v0e2 76252 1417236_at Ehd3 57440 1424770_at Cald1 109624 1452308_a_at Atp1a2 98660 1417497_at Cp 12870 1435106_at Limch1 77569 1448239_at Hmox1 15368 1420378_at Sftpd 20390 1418243_at Fcna 14133 1437902_s_at Rarres2 71660 1430700_a_at Pla2g7 27226 1423456_at Bzw2 66912 1418175_at Vdr 22337 1418174_at Dbp 13170 1419144_at Cd163 93671 1460346_at Arsa 11883 1417580_s_at Selenbp1 20341 1422740_at Tnfrsf21 94185 Table S4 (Goes with Figure 4). Gene clusters that are induced within the subgroups of Figure 4A.

Cluster-a Cluster-b Cluster-c APLP2 PYGL AASS SELENBP1 ADM H6PD PTX3 APOD SERPINA3 AKAP12 SELP ALAS2 HAL RAB6B ARHGEF10 SERPINI1 ARHGAP29 SHOX2 AMHR2 HLA-DQA1 RARRES2 ATP6V0E2 SFTPD ATP1A2 SIDT1 AP2A2 HMOX1 REG1A BZW2 SGK269 CALD1 SLC12A2 ARC ID4 RGS17 C10orf81 SLC12A8 CD36 STARD13 ARSA IL18R1 RNASE2 CCL2 SLC47A1 CMA1 TACSTD2 CALCA IL6 RUNX2 CLIP4 STMN2 COL4A5 TFAP2B CALCB KCNB1 SAP30 CXXC1 TCEA2 CPA3 TNFSF10 CAPN3 LAMB3 SCN7A DCLK1 TM4SF1 CYP4B1 TNXB CAPN6 LDB3 SCRG1 EMP2 TNFRSF11B DBP TSC22D3 CD163 LPAR3 SECTM1 ENO2 TNFRSF21 EHD3 TTC28 CDKN2A MAPK12 SEMA4F ERO1L TSPAN8 ESRRG VCAN CP MDFIC SERPINB2 ETNK1 ZBTB7C EVC ZFHX4 CSN2 MEG3 SERPINB5 FCGRT FGFR4 ZFPM2 CXCL11 MYO7A SERPINE1 FRMD4B GPM6A CXCL9 NCK1 SIM2 GFRA1 GSTT2 DMP1 NEFM SLC12A3 GUSB GUCY1B3 DST NFE2L3 SLC6A14 HDAC11 ITIH5 EYA4 NNMT SLC7A6 HOMER2 KIAA1324 F13A1 NPR3 SNCA HSPA1A LEPR FAM46C PAK3 SOSTDC1 IGFBP2 LIMCH1 FCN1 PFN2 SOX2 MAGI2 LMCD1 FETUB PKP1 STK17B MBTPS1 LTBP2 FGF4 PLA2G4A TFEC NAV2 LYPD3 FLVCR2 PLA2G7 TP63 NEDD9 LYVE1 FMO2 PPBP TTN PANK3 MMP19 FOLR2 PRKD1 UCHL1 PGF MYO5C GJB3 PRSS22 VDR PIPOX PDK4 GJB4 PRTN3 WWP2 PMAIP1 PLCB4 GLIPR1 PTGER2 POT1 RCN3 GPRC5B PTGER4 Table S5 (Goes with Figure 4).

Tabl e S5 . Bi ol ogi cal f uncti ons of 323 -IHC genes Mammary Stem Cells Direction of Direction of Direction of Symbol Change Symbol Change Symbol Change Arc Up Il6 Down Pkp1 Up Atp6v0e2 Down Kiaa1324 Down Pla2g7 Up Cd36 Down Lamb3 Up Rarres2 Down Cgnl1 Down Lars Down Rcn3 Down Evc Down Lypd3 Up Sidt1 Down Hdac 11 Down M5Myo5c Down Snca Down Homer2 Down Nnmt Down Trp63 Up Id4 Up Pgf Down Vcan Up Igfbp2 Up

Immune Response Direction of Direction of Direction of Symbol Change Symbol Change Symbol Change Calcb* Down Hsh2d* Up Ptger2* Up Ccl13* Down Ighm* Down Ptger4* Up Ccl6 Down Il18r1 Up Ptx3* Down Ccl8 Down Il20rb* Down Raet1a Down Cd163 Down Il6* Down Rarres2 Down Cd36 Down Mrc1 Down Rnase2 Down Cd69 Up Myo7a Down Sectm1 Up Cdkn2a* Down Nck1* Down Selp Down Cxcl11 Up Nedd9* Up Serpina3 Down

Cxcl9* Up Pf4* Down Serpine1* Down Ear2 Down Pgf* Down Sftpd* Up Fcgrt Down Pla2g4a* Up Sh2d1b Up H60a* Down Pla2g7 Up Snca* Down Hla-b Up Pmaip1* Up Stk17b* Down Hla-dqa1 Up Ppbp Down Tnfsf10* Up Hmox1* Down Prtn3* Up Vdr* Up

Proliferation Direction of Direction of Direction of Symbol Change Symbol Change Symbol Change Adm Down Igfbp2 Up Shox2 Down Cd36 Down Lepr Down Sox2 Down Cma1 Down Lpar3 Up Sox8 Up Dmp1 Up Mapk12 Down Stard13 Down Ero1l Down Mmp19 Down Synm Down

Fgf4 Down Pcyt1b Up Tnfrsf11b Up Fgfr4 Up Prkd1 Up Tnfrsf21 Up Foxp2 Down Reg1a Down Trp63 Up Ggt1 Up Runx2 Up Tsc22d3 Down Gstm1 Down Sectm1b Up Vcan Up Has3 Down Serpinb2 Down Vsig4 Down Id4 Up Serpinb5 Up Wwp2 Up

*Also involved in "Proliferation of Eukaryotic Cells" as annotated in Ingenuity Pathway Analysis. Figure S2 (Goes with Figure 4)

A Luminal A HER2 Normal Like Luminal B Basal-like No Subtype

Group 1A Group 1B Group 2C Group 2D

B C Table S6 (Goes with Figures 5 & 6). Gene lists for gene clusters in Figure 5A and 6C.

Figure 5A Gene Clusters Figure 6C Gene Clusters Gene Gene Gene Cluster-a Cluster-b Cluster-c Gene Gene Gene Cluster C ADM AASS NEDD9 ADHFE1 NFIA Cluster A Cluster B PBX3 STMN2 PLP1 CBR3 PIK3R1 FMOD ARHGEF10 AKAP12 NNMT ANKRD22 PANK3 ATP1A2 FGG EPHX1 MYL9 SCARA3 HJURP IER3 GAS6 CALCA APOC1 PDK4 ARHGAP29 PMAIP1 CLU PTPLA PKP4 FBLN1 CALCB VWA1 TEAD4 IGFBP2 RBMS3 ATP1A2 PDZD2 BZW2 PRKAA2 SLC29A1 CDH2 NPNT GPR124 PLA2G CAPN6 FBLN7 NT5E BBS1 CPXM2 CALD1 7CGNL1SAP30PNKD ZNF503 MREG PDPN C3orf54 ATP8B2 CA12 SFRP2 CDKN2A CCL2 PRKD1 CHDH SBSN CLEC11A TRIB2 FLRT3 CTHRC1 PTGER CLIP4 PLCH2 IGF2R CYB561 VCAN CCL8 2 CLCA2 SCN7A FAT2 SOX4 ATP1B1 COL5A2 PTGER DST LOC39094 LMO1 LYPLA1 KIF26B CD163 4 CLIC6 SEC16B 0 SGCE CANX FIBIN PELI2 PPARGC1 DAAM1 LMCD1 FAM171A1 CD36 PYGL COL4A5 SERPINI1 PEA15 A ISYNA1 C20orf103 RAPGE ID4 C10orf99 PLAGL1 CCRN4L SNAI2 CD69 F5 CYP4B1 SFTPD WIPF2 CXCL1 PRSS35 GPX7 RARRE IGSF3 CSF3 KRT16 ATP8A1 S100A4 CMA1 S2 DBP SIDT1 APOD DSC3 ZNF23 C14orf37 IL20RB CPA3 RBP7 DDAH1 SLC12A2 GPR50 PPP1R14C SIGLEC5 GADD45A MXD1 PROM1 ID2 TMEM45A LAMB3 CXCL11 RCN3 EMP2 SPIRE1 CSF3R FAM171A1 SLCO2A1 S100A9 PDGFRA SLPI GLRX MUC15 CXCL9 RUNX2 ERO1L TACSTD2 APBB1 SOSTDC1 MAP3K8 NAV2 ACTG2 CHST11 EMB SHOX2 FGFR4 TCEA2 KRT5 SAMSN1 SLCO2 NPR3 COL17A1 CLEC4E F13A1 B1 GFRA1 TSC22D3 DST CD14 PFN2 ID4 IL1B FAM26F STK17B GGT1 TTLL7 RCAN1 TM7SF4 PLA2G4A, FCGRT STMN2 GPM6A VDR ERRFI1 MBD2 COL27A1 MRS2 PLCB4 FMO2 TMTC1 GSTT2 TSPAN6 CASP3 TNFSF1 ANKRD22 PTX3 FOLR2 0HDAC11 PTEN PCDH7 SCRG1 FRMD4B TNXB HOMER2 ESM1 TPSAB PMM2 SERPINB5 GALNTL2 1 HSPA1A FAM70A

SNCA GUCY1B3 TTC28 IGFBP2

SOSTDC1 HMOX1 VCAN LARS

SOX8 IL6 VSIG4 LIMCH1

SYNM ITIH5 ZFHX4 LRP11

TM4SF1 LGI2 ZFPM2 LTBP2

TNFRSF21 LMCD1 MAGI2

UCHL1 LYVE1 MBTPS1

WNT10A MMP19 MYO5C

WWP2 NCK1 NFE2L3