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Identifying COPD by Crackle Characteristics
BMJ Open Resp Res: first published as 10.1136/bmjresp-2020-000852 on 5 March 2021. Downloaded from Respiratory epidemiology Inspiratory crackles—early and late— revisited: identifying COPD by crackle characteristics Hasse Melbye ,1 Juan Carlos Aviles Solis,1 Cristina Jácome,2 Hans Pasterkamp3 To cite: Melbye H, Aviles ABSTRACT Key messages Solis JC, Jácome C, et al. Background The significance of pulmonary crackles, Inspiratory crackles— by their timing during inspiration, was described by Nath early and late—revisited: and Capel in 1974, with early crackles associated with What is the key question? identifying COPD by bronchial obstruction and late crackles with restrictive ► In the diagnosis of chronic obstructive pulmonary crackle characteristics. defects. Crackles are also described as ‘fine’ or disease (COPD), is it more useful to focus on the tim- BMJ Open Resp Res ‘coarse’. We aimed to evaluate the usefulness of crackle ing of crackles than on the crackle type? 2021;8:e000852. doi:10.1136/ bmjresp-2020-000852 characteristics in the diagnosis of chronic obstructive What is the bottom line? pulmonary disease (COPD). ► Pulmonary crackles are divided into two types, ‘fine’ Methods In a population-based study, lung sounds Received 2 December 2020 and ‘coarse’ and coarse inspiratory crackles are re- Revised 2 February 2021 were recorded at six auscultation sites and classified in garded to be typical of COPD. In bronchial obstruc- Accepted 5 February 2021 participants aged 40 years or older. Inspiratory crackles tion crackles tend to appear early in inspiration, and were classified as ‘early’ or ‘late and into the types’ this characteristic of the crackle might be easier for ‘coarse’ and ‘fine’ by two observers. -
Age-Related Pulmonary Crackles (Rales) in Asymptomatic Cardiovascular Patients
Age-Related Pulmonary Crackles (Rales) in Asymptomatic Cardiovascular Patients 1 Hajime Kataoka, MD ABSTRACT 2 Osamu Matsuno, MD PURPOSE The presence of age-related pulmonary crackles (rales) might interfere 1Division of Internal Medicine, with a physician’s clinical management of patients with suspected heart failure. Nishida Hospital, Oita, Japan We examined the characteristics of pulmonary crackles among patients with stage A cardiovascular disease (American College of Cardiology/American Heart 2Division of Respiratory Disease, Oita University Hospital, Oita, Japan Association heart failure staging criteria), stratifi ed by decade, because little is known about these issues in such patients at high risk for congestive heart failure who have no structural heart disease or acute heart failure symptoms. METHODS After exclusion of comorbid pulmonary and other critical diseases, 274 participants, in whom the heart was structurally (based on Doppler echocar- diography) and functionally (B-type natriuretic peptide <80 pg/mL) normal and the lung (X-ray evaluation) was normal, were eligible for the analysis. RESULTS There was a signifi cant difference in the prevalence of crackles among patients in the low (45-64 years; n = 97; 11%; 95% CI, 5%-18%), medium (65-79 years; n = 121; 34%; 95% CI, 27%-40%), and high (80-95 years; n = 56; 70%; 95% CI, 58%-82%) age-groups (P <.001). The risk for audible crackles increased approximately threefold every 10 years after 45 years of age. During a mean fol- low-up of 11 ± 2.3 months (n = 255), the short-term (≤3 months) reproducibility of crackles was 87%. The occurrence of cardiopulmonary disease during follow-up included cardiovascular disease in 5 patients and pulmonary disease in 6. -
Assessing and Managing Lung Disease and Sleep Disordered Breathing in Children with Cerebral Palsy Paediatric Respiratory Review
Paediatric Respiratory Reviews 10 (2009) 18–24 Contents lists available at ScienceDirect Paediatric Respiratory Reviews CME Article Assessing and managing lung disease and sleep disordered breathing in children with cerebral palsy Dominic A. Fitzgerald 1,3,*, Jennifer Follett 2, Peter P. Van Asperen 1,3 1 Department of Respiratory Medicine, University of Sydney, Sydney, New South Wales, Australia 2 Department of Physiotherapy, The Children’s Hospital at Westmead, University of Sydney, Sydney, New South Wales, Australia 3 The Children’s Hospital at Westmead Clinical School, Discipline of Paediatrics & Child Health, University of Sydney, Sydney, New South Wales, Australia EDUCATIONAL AIMS To appreciate the insidious evolution of suppurative lung disease in children with cerebral palsy (CP). To be familiar with the management of excessive oral secretions in children with CP. To understand the range of sleep problems that are more commonly seen in children with CP. To gain an understanding of the use of non-invasive respiratory support for the management of airway clearance and sleep disordered breathing in children with CP. ARTICLE INFO SUMMARY Keywords: The major morbidity and mortality associated with cerebral palsy (CP) relates to respiratory compromise. Cerebral palsy This manifests through repeated pulmonary aspiration, airway colonization with pathogenic bacteria, Pulmonary aspiration the evolution of bronchiectasis and sleep disordered breathing. An accurate assessment involving a Suppurative lung disease multidisciplinary approach and relatively simple interventions for these conditions can lead to Physiotherapy significant improvements in the quality of life of children with CP as well as their parents and carers. This Airway clearance techniques Obstructive sleep apnoea review highlights the more common problems and potential therapies with regard to suppurative lung Sleep disordered breathing disease and sleep disordered breathing in children with CP. -
Problems in Family Practice
problems in Family Practice Coughing in Childhood Hyman Sh ran d , M D Cambridge, M assachusetts Coughing in childhood is a common complaint involving a wide spectrum of underlying causes which require a thorough and rational approach by the physician. Most children who cough have relatively simple self-limiting viral infections, but some may have serious disease. A dry environment, allergic factors, cystic fibrosis, and other major illnesses must always be excluded. A simple clinical approach, and the sensible use of appropriate investigations, is most likely to succeed in finding the cause, which can allow precise management. The cough reflex as part of the defense mechanism of the respiratory tract is initiated by mucosal changes, secretions or foreign material in the pharynx, larynx, tracheobronchial Table 1. Persistent Cough — Causes in Childhood* tree, pleura, or ear. Acting as the “watchdog of the lungs,” the “good” cough prevents harmful agents from Common Uncommon Rare entering the respiratory tract; it also helps bring up irritant material from Environmental Overheating with low humidity the airway. The “bad” cough, on the Allergens other hand, serves no useful purpose Pollution Tobacco smoke and, if persistent, causes fatigue, keeps Upper Respiratory Tract the child (and parents) awake, inter Recurrent viral URI Pertussis Laryngeal stridor feres with feeding, and induces vomit Rhinitis, Pharyngitis Echo 12 Vocal cord palsy Allergic rhinitis Nasal polyp Vascular ring ing. It is best suppressed. Coughs and Prolonged use of nose drops Wax in ear colds constitute almost three quarters Sinusitis of all illness in young children. The Lower Respiratory Tract Asthma Cystic fibrosis Rt. -
Chest Pain in a Patient with Cystic Fibrosis
Copyright ©ERS Journals Ltd 1998 Eur Respir J 1998; 12: 245–247 European Respiratory Journal DOI: 10.1183/09031936.98.12010245 ISSN 0903 - 1936 Printed in UK - all rights reserved CASE FOR DIAGNOSIS Chest pain in a patient with cystic fibrosis D.P. Dunagan*, S.L. Aquino+, M.S. Schechter**, B.K. Rubin**, J.W. Georgitis** Case history A 38 yr old female with a history of cystic fibrosis (CF) presented to an outside emergency department with dysp- noea and right-sided chest pain of approximately 12 h duration. Her history was significant for recurrent pneu- mothoraces and a recent respiratory exacerbation of CF requiring prolonged antibiotic therapy for Pseudomonas aeruginosa. She described the pain as relatively acute in onset, sharp, increased with deep inspiration, without out- ward radiation, and progressive in intensity. There was no history of travel, worsening cough, fever, chills or increase in her chronic expectoration of blood-streaked sputum. An outside chest radiograph was interpreted as demonstrating a "rounded" right lower lobe pneumonia and she was transferred to our institution for further evaluation. Fig. 2. – Computed tomography scan of the chest. Open arrow: multi- On examination, she was thin, afebrile and in minimal ple cysts; closed white arrow: 3.8×5 cm round mass, respiratory distress. There were decreased breath sounds throughout all lung fields, symmetric chest wall excursion with inspiration and bilateral basilar crackles. Subjective right lateral chest discomfort was reported with deep ins- piratory manoeuvres. The remaining physical examination was normal except for clubbing of the upper extremities. Laboratory data revealed an elevated white blood cell count of 19.2×109 cells·L-1 with a normal differential. -
CHEST RADIOLOGY: Goals and Objectives
Harlem Hospital Center Department of Radiology Residency Training Program CHEST RADIOLOGY: Goals and Objectives ROTATION 1 (Radiology Years 1): Resident responsibilities: • ED chest CTs • Inpatient and outpatient plain films including the portable intensive care unit radiographs • Consultations with referring clinicians MEDICAL KNOWLEDGE: • Residents must demonstrate knowledge about established and evolving biomedical, clinical, and cognitive sciences and the application of this knowledge to patient care. At the end of the rotation, the resident should be able to: • Identify normal radiographic and CT anatomy of the chest • Identify and describe common variants of normal, including aging changes. • Demonstrate a basic knowledge of radiographic interpretation of atelectasis, pulmonary infection, congestive heart failure, pleural effusion and common neoplastic diseases of the chest • Identify the common radiologic manifestation of thoracic trauma, including widened mediastinum, signs of aortic laceration, pulmonary contusion/laceration, esophageal and diaphragmatic rupture. • Know the expected postoperative appearance in patients s/p thoracic surgery and the expected location of the life support and monitoring devices on chest radiographs of critically ill patients (intensive care radiology); be able to recognize malpositioned devices. • Identify cardiac enlargement and know the radiographic appearance of the dilated right vs. left atria and right vs. left ventricles, and pulmonary vascular congestion • Recognize common life-threatening -
成人のstridorへの アプローチ 筑波大学総合診療グループ 細井崇弘 監修 筑波大学総合診療グループ 五十野博基 2017年3月9日
成人のstridorへの アプローチ 筑波大学総合診療グループ 細井崇弘 監修 筑波大学総合診療グループ 五十野博基 2017年3月9日 分野:呼吸器 テーマ:診断 症例78歳女性 主訴 呼吸困難 当院は医療過疎地にある100床程度の小規模病院。 【現病歴】高血圧、糖尿病で近医通院中。入院数日前から咳嗽がみら れていた。入院当日に近医を受診し、胸部レントゲン検査を受け肺炎 の疑いと診断され帰宅した。 20時近くまでは同居の娘が異常が無い事を確認。 24時頃に娘が帰宅すると、獣の鳴くような声が聞こえ、患者のもとに 駆け付けると呼吸苦を訴えており、救急車を要請し当院へ搬送された。 【既往歴】高血圧、糖尿病。喘息無し。 【喫煙歴】なし 入院時現症 来院時、自発開眼しているが、会話困難。 Vital sign:BP 145/90mmHg, HR 130/min, RR36/min,SpO2 86%, BT 38℃ 頸部 Stridorを聴取 BVMによる呼吸補助開始するも換気不良 上気道閉塞と判断し、7mmチューブで経口気管挿管 このとき喉頭蓋の浮腫(-) BGA(Vein):pH 7.08, PaO2 63Torr, PCO2 99.9 Torr 胸部所見では両側に軽度の coarse cracklesあり 腹部所見は異常なし 症例の経過 • インフルエンザA(+) • 呼吸器管理となり入院、ラピアクタ投与と鎮痛・鎮静 • CO2ナルコーシスは改善、耳鼻科と共に喉頭ファイバーで声門より 上部に狭窄病変が無い事を確認。 • 意識レベルも清明であり従命可能、自発呼吸も良好であり抜管 抜管後は発語もあり問題なかったが、10数分で呼吸困難を訴え、 SpO2が急激に低下したため再挿管。 再挿管時、声帯は確認できたがチューブが声帯を越えるのに非常に 難渋した。 Stridorは何が原因だったのか? 抜管による喉頭浮腫? では救急外来に来た際の最初のStridorは? Stridorが聞こえたが喉頭蓋炎ではなかったとき、 どのような鑑別疾患を上げ、 どのようにアプローチするのが良かったのか? Clinical Ques3on • 成人で気道狭窄が疑われる場合 ①鑑別診断は何か? ②初期診断のためのアプローチは? Stridorとは~身体診察~ • 強い楽音様の音で、明確な一定の音調(一般に400Hz前後)であり、 通過障害(閉塞)を示唆する。 ・Stridorは吸気時に限られる ・Stridorは常に頸部でより強く聴取されるが、wheezingは常に胸部で 聴取される。Am Rev Respir Dis.1983;143:890-892 ・気道の直径が8㎜以下になると労作時呼吸困難が出現し、 Crit Care Med 2004; 169: 1278-1297. ・気道の直系が5mm以下で安静時にも呼吸苦が出現する。 JAMA.1971;216:1984-1985 気道狭窄の分類 upper airway obstrucYon(UAO) Central airway obstrucYon(CAO) Lower airway obstrucYon(LAO) 口から(鼻腔含め)喉頭. 慢性的な閉塞性肺傷害、喘息や : :気管および主気管支 : CAOと同時に認められることも COPDなど。CAOやUAOとは典型 的には合併しない。 発症率などの疫学については、 (悪性腫瘍以外の例では) 成人での発生頻度が非常にまれであり、 詳しくは分かっていない。 Up to date: Clinical presentaon , diagnosYc evaluaon,and management of -
Respiratory Failure
Respiratory Failure Phuong Vo, MD,* Virginia S. Kharasch, MD† *Division of Pediatric Pulmonary and Allergy, Boston Medical Center, Boston, MA †Division of Respiratory Diseases, Boston Children’s Hospital, Boston, MA Practice Gap The primary cause of cardiopulmonary arrest in children is unrecognized respiratory failure. Clinicians must recognize respiratory failure in its early stage of presentation and know the appropriate clinical interventions. Objectives After completing this article, readers should be able to: 1. Recognize the clinical parameters of respiratory failure. 2. Describe the respiratory developmental differences between children and adults. 3. List the clinical causes of respiratory failure. 4. Review the pathophysiologic mechanisms of respiratory failure. 5. Evaluate and diagnose respiratory failure. 6. Discuss the various clinical interventions for respiratory failure. WHAT IS RESPIRATORY FAILURE? Respiratory failure is a condition in which the respiratory system fails in oxy- genation or carbon dioxide elimination or both. There are 2 types of impaired gas exchange: (1) hypoxemic respiratory failure, which is a result of lung failure, and (2) hypercapnic respiratory failure, which is a result of respiratory pump failure (Figure 1). (1)(2) In hypoxemic respiratory failure, ventilation-perfusion (V_ =Q)_ mismatch results in the decrease of PaO2) to below 60 mm Hg with normal or low PaCO2. _ = _ (1) In hypercapnic respiratory failure, V Q mismatch results in the increase of AUTHOR DISCLOSURE Drs Vo and Kharasch fi PaCO2 to above 50 mm Hg. Either hypoxemic or hypercapnic respiratory failure have disclosed no nancial relationships can be acute or chronic. Acute respiratory failure develops in minutes to hours, relevant to this article. -
Internal Medicine Vol.60
doi: 10.2169/internalmedicine.5120-20 Intern Med 60: 453-456, 2021 http://internmed.jp 【 CASE REPORT 】 Peribronchial Connective Tissue Infection Caused by Bifidobacterium longum and Veillonella Species Mimicking Lung Cancer Yasuo Takiguchi 1, Masaru Nagayosi 1, Yukiko Matsuura 1, Yoko Akiba 2 and Akira Naito 3 Abstract: An 86-year-old woman was admitted for the investigation of atelectasis of the upper lobe of her right lung with a mass shadow in the hilum (Golden S sign). Chest computed tomography revealed swollen connective tissue around the right bronchus, and needle aspirate grew Bifidobacterium longum and Veillonella species. She was diagnosed with peribronchial connective tissue infection, and her condition improved with antibiot- ics. Although this sign is strongly suggestive of malignant disease, benign disease should be considered in the differential diagnosis. Pulmonary infection caused by Bifidobacterium longum is extremely rare; however, clinicians should consider it as a possible cause of pulmonary infections. Key words: peribronchial connective tissue infection, Bifidobacterium longum, Veillonella, Golden S sign (Intern Med 60: 453-456, 2021) (DOI: 10.2169/internalmedicine.5120-20) with wheeze and general malaise as her chief complaints. Introduction Chest radiography revealed atelectasis of the upper lobe of her lung with a mass shadow in the right hilum (the Golden Atelectasis of the right upper lobe of the lung with mass S sign). These findings suggested a diagnosis of lung can- shadow in the right hilum on chest radiograph is known as cer, and she was admitted to our hospital for a further inves- the Golden S sign (inverted S sign), and typically associated tigation. -
Pneumonia (CAP)
肺實質化病變與肺塌陷 胸腔內科周百謙醫師 Dr. Pai-chien Chou MD PhD Department of Thoracic Medicine Taipei Medical University Hospital Chest X-ray • P-A view • Lateral view • Oblique view • Lordotic view • Expiratory film • Decubitus view • Overpenetrated grid film The Elements of a chest x-ray (CXR) • The Broncho-vascular markings in the lung • The borders of the heart • The contours of the mediastinum and pleural space • The ribs and spine Segmental anatomy Segmental Anatomy Cardiomediastinal outlines on Chest X-ray Density of image ◆ Gas ◆ Water ◆ Fat ◆ Metal and bone ◆ Thinking of pathogenesis Basic thinking of a lesion on Chest X-ray ◆ Size ◆ Location (Silhouette sign) – Anterior, posterior – Which lobe is involved ◆ Intrapulmonary (Air bronchogram sign) ◆ Extrapulmonary (Incomplete border sign) Infiltrate in the lungs • Fluid accumulates in lung, predominate in the alveolar (airspace) compartment or the interstitial compartment. interstitial compartment Lymphatic compartment Alveolar unit Vascular unit Air space opacification The opacification is caused by fluid or solid material within the airways that causes a difference in the relative attenuation of the lung: • transudate, e.g. pulmonary edema secondary to heart failure • pus, e.g. bacterial pneumonia • blood, e.g. pulmonary hemorrhage • cells, e.g. bronchoalveolar carcinoma • protein, e.g. alveolar proteinosis • fat, e.g. lipoid pneumonia • gastric contents, e.g. aspiration pneumonia • water, e.g. drowning When considering the likely causes of airspace opacification, it is useful to determine chronicity -
Signs in Chest Imaging
Diagn Interv Radiol 2011; 17:18–29 CHEST IMAGING © Turkish Society of Radiology 2011 PICTORIAL ESSAY Signs in chest imaging Oktay Algın, Gökhan Gökalp, Uğur Topal ABSTRACT adiological practice includes classification of illnesses with similar A radiological sign can sometimes resemble a particular object characteristics through recognizable signs. Knowledge of and abil- or pattern and is often highly suggestive of a group of similar pathologies. Awareness of such similarities can shorten the dif- R ity to recognize these signs can aid the physician in shortening ferential diagnosis list. Many such signs have been described the differential diagnosis list and deciding on the ultimate diagnosis for for X-ray and computed tomography (CT) images. In this ar- ticle, we present the most frequently encountered plain film a patient. In this report, 23 important and frequently seen radiological and CT signs in chest imaging. These signs include for plain signs are presented and described using chest X-rays, computed tomog- films the air bronchogram sign, silhouette sign, deep sulcus raphy (CT) images, illustrations and photographs. sign, Continuous diaphragm sign, air crescent (“meniscus”) sign, Golden S sign, cervicothoracic sign, Luftsichel sign, scim- itar sign, doughnut sign, Hampton hump sign, Westermark Plain films sign, and juxtaphrenic peak sign, and for CT the gloved finger Air bronchogram sign sign, CT halo sign, signet ring sign, comet tail sign, CT an- giogram sign, crazy paving pattern, tree-in-bud sign, feeding Bronchi, which are not normally seen, become visible as a result of vessel sign, split pleura sign, and reversed halo sign. opacification of the lung parenchyma. -
Eponyms in Radiologic Signs
Eponyms in radiologic signs Poster No.: C-0133 Congress: ECR 2014 Type: Educational Exhibit Authors: D. Andrade, L. Andrade, M. Magalhaes, L. Curvo-Semedo, F. Caseiro Alves; Coimbra/PT Keywords: Diagnostic procedure, Fluoroscopy, CT, Conventional radiography, Thorax, Musculoskeletal system, Gastrointestinal tract, Education and training DOI: 10.1594/ecr2014/C-0133 Any information contained in this pdf file is automatically generated from digital material submitted to EPOS by third parties in the form of scientific presentations. References to any names, marks, products, or services of third parties or hypertext links to third- party sites or information are provided solely as a convenience to you and do not in any way constitute or imply ECR's endorsement, sponsorship or recommendation of the third party, information, product or service. ECR is not responsible for the content of these pages and does not make any representations regarding the content or accuracy of material in this file. As per copyright regulations, any unauthorised use of the material or parts thereof as well as commercial reproduction or multiple distribution by any traditional or electronically based reproduction/publication method ist strictly prohibited. You agree to defend, indemnify, and hold ECR harmless from and against any and all claims, damages, costs, and expenses, including attorneys' fees, arising from or related to your use of these pages. Please note: Links to movies, ppt slideshows and any other multimedia files are not available in the pdf version of presentations. www.myESR.org Page 1 of 43 Learning objectives 1. To recognize the most frequent and important radiologic signs that are eponyms.