Authors: Pallavi Subhraveti Ron Caspi Quang Ong Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_001434845Cyc: Lactobacillus hordei DSM 19519 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari 1-(β-D uracilxanthine spermidine spermidine sn-glycerol ribofuranosyl) uracil putrescine putrescine 3-phosphate D-mannitol nicotinamide

cis-vaccenate a 2,3,4-saturated fatty acid predicted predicted ABC predicted ABC transporter PEP-driven RS05785 RS00955 RS07845 RS06140 RS04575 RS07010 RS08465 RS08935 RS04930 RS08460 RS08865 RS02995 RS08170 RS04480 RS04150 RS06630 RS03420 RS11045 RS04175 RS04840 RS01640 RS06290 RS08025 RS02760 RS04355 RS00180 RS08475 RS07670 RS09215 RS09110 RS05520 RS08670 transporter RS10810 RS04415 RS06495 RS05900 RS09065 RS06220 RS00460 RS07925 RS10525 RS03810 RS08895 RS09620 RS07900 RS04425 RS03625 RS00385 RS05355 RS08610 RS07105 RS06420 RS11100 RS07020 RS03645 RS09735 RS03545 RS03425 RS04775 RS01855 RS08820 RS10965 RS02560 RS07725 RS03165 RS06665 RS10825 RS06960 of sn- transporter of putrescine/ glycerol 3- of D-mannitol spermidine phosphate uracil uracil spermidine cis-vaccenoyl-CoA 1-(β-D putrescine a 2,3,4-saturated fatty acyl CoA ribofuranosyl) xanthine D-mannitol nicotinamide spermidine 1-phosphate putrescine sn-glycerol 3-phosphate

Nucleoside and Nucleotide Degradation Secondary RS09755 Cofactor, Prosthetic Group, Electron Carrier, and Vitamin Biosynthesis Fermentation Amine and Polyamine Metabolite Biosynthesis an inactive 1939 a (7Z,10Z,13Z inosine 5'-phosphate guanosine nucleotides Degradation a (6S)-5- a ribonucleoside a uracil a cis-delta21-3- dCDP [2Fe-2S] iron-sulfur cluster biosynthesis ribonucleoside a reduced quinoxaline-2- acyl-carrier protein Glu NMN ,16Z,19Z)-3- 1,4-dihydroxy-2- L-cysteine biosynthesis NAD biosynthesis N 10 -formyl-tetrahydrofolate biosynthesis heterolactic fermentation degradation degradation III SAM adenine PRPP 5'-monophosphate in 23S rRNA AMP IMP phosphopantothenate biosynthesis I lipoate salvage I hydroxymethylpyrimidine menaquinol-9 biosynthesis menaquinol-6 biosynthesis putrescine mannitol carboxyl adenylate formyltetrahydrofolate 23S rRNA (uracil-5- oxo-C40:1-[acp] ribonucleotide- RS10995 naphthoate biosynthesis VI (from L-methionine) I (from aspartate) triphosphate flavodoxin acyl carrier bifunctional multifunctional 2',3'- multifunctional 2',3'- oxodocosa- 3-oxoacyl-[acyl- RS08490 salvage biosynthesis III degradation I anaerobic adenine )-methyltransferase bifunctional bifunctional diphosphate RS10890 3-methyl-2- a 5,10- β-D-fructofuranose reductase protein: folylpolyglutamate cyclic-nucleotide 2'- cyclic-nucleotide 2'- 7,10,13,16,19-3-oxoacyl-[acyl- carrier-protein] L-cysteine desulfurase a tetrahydrofolate ribonucleoside- phosphoribosyltransferase: RumA: metallophosphatase/ metallophosphatase/ reductase chorismate oxobutanoate methylenetetrahydrofolate (R)-lipoate 4-amino-2-methyl-5- demethylmenaquinol-9 demethylmenaquinol-6 IMP GMP D-mannitol FC92_RS02620 synthase/ phosphodiesterase/ phosphodiesterase/ pentaenoyl-[acp]carrier-protein] reductase: met asp triphosphate FC92_RS09120 FC92_RS01285 5'-nucleotidase: 5'-nucleotidase: subunit beta: cysteine isochorismate lipoate-- pyrimidinemethanol bifunctional bifunctional L-ornithine IMP bifunctional 1-phosphate acyl carrier dihydrofolate 5'-nucleotidase/ 5'-nucleotidase/ reductase: FC92_RS02630 predicted methionine bifunctional fructokinase: mannitol-1- reductase adenine FC92_RS04290 FC92_RS04290 FC92_RS06670 desulfurase: synthase: protein ligase: demethylmenaquinone demethylmenaquinone ornithine dehydrogenase: metallophosphatase/ protein: synthase: 3'-nucleotidase: 3'-nucleotidase: 23S rRNA (uracil-5- FC92_RS02630 3-oxoacyl-ACP ABC adenosyltransferase: hydroxymethylpyrimidine FC92_RS06800 phosphate 5- activating protein: phosphoribosyltransferase: ribonucleoside- FC92_RS03105 FC92_RS05650 FC92_RS05500 methyltransferase/2- methyltransferase/2- decarboxylase: FC92_RS08790 5'-nucleotidase: FC92_RS03280 FC92_RS06040 FC92_RS08880 FC92_RS08880 )-methyltransferase multifunctional 2',3'- multifunctional 2',3'- reductase: RS00735 RS07055 met transporter met FC92_RS05210 2-iminosuccinate kinase/ methoxy-6-polyprenyl-1,4- methoxy-6-polyprenyl-1,4- XMP FC92_RS04290 dehydrogenase: FC92_RS02260 an active FC92_RS07180 3-oxoacyl-ACP diphosphate isochorismate SAM lipoate-- FC92_RS10620 D-glucopyranose a quinoxaline-2- a (6S)-5- bifunctional RumA: cyclic-nucleotide 2'- cyclic-nucleotide 2'- FC92_RS02370 of L- an S-sulfanyl-[L- 2-dehydropantoate phosphomethylpyrimidine benzoquinol methylase: benzoquinol methylase: putrescine FC92_RS05760 a flavodoxin met 5'-deoxyadenosine ribonucleoside bifunctional a (3R,7Z,10reductase:Z a cis-delta21-3- reductase protein ligase: F6P multifunctional 2',3'- F6P AMP carboxyl-[aryl- AMP formyltetrahydrofolate metallophosphatase/ FC92_RS03945 phosphodiesterase/ phosphodiesterase/ methionine cysteine desulfurase] 2-succinyl-6- kinase: FC92_RS09445 FC92_RS04530 FC92_RS04530 bifunctional semiquinone triphosphate metallophosphatase/ a 5- ,13Z,16Z,19ZFC92_RS02370)-3- hydroxyC40:1- subunit alpha: FC92_RS08185 carrier protein] 5'-nucleotidase: 1939 5'-nucleotidase/ 5'-nucleotidase/ 2-dehydropantoate HMP-P cyclic-nucleotide 2'- reductase 5'-nucleotidase: methyluracil hydroxydocosa- [acp] RS08435 hydroxy-2, 4- lipoyl-adenylate menaquinol-9 menaquinol-6 glucokinase: metallophosphatase/ FC92_RS04290 3'-nucleotidase: 3'-nucleotidase: FC92_RS06675 2-reductase: Fatty Acid and Lipid Biosynthesis glucose-6- phosphodiesterase/ FC92_RS04290 1-(β-D in 23S rRNA 7,10,13,16,19- RS04780 RS07065 cyclohexadiene- FC92_RS10575 bifunctional folate polyglutamylation FC92_RS03395 5'-nucleotidase: 5'-nucleotidase/ FC92_RS08880 FC92_RS08880 CDP quinolinate serine lipoate-- phosphate a ribonucleoside ribofuranosyl) pentaenoyl-[acp] 1-carboxylate a 7,8-dihydrofolate a 5-methyltetrahydrofolate hydroxymethylpyrimidine FC92_RS04290 3'-nucleotidase: adenosine inosine an S-sulfanyl-[cysteine SAH hydroxymethyltransferase: glyA 2-dehydropantoate protein ligase: isomerase: nicotinamide synthase: kinase/ palmitate biosynthesis II (bacteria and plants) multifunctional 2',3'- FC92_RS08880 desulfurase]-[disordered- FC92_RS05640 2-reductase: FC92_RS05500 a tetrahydrofolate phosphatidylglycerol cyclopropane pgi RS10155 form scaffold thymidylate FC92_RS10580 phosphomethylpyrimidine fatty acid (CFA) cyclic-nucleotide 2'- guanosine 5'-methylthioadenosine/ lipoate-- biosynthesis II (non-plastidic) protein] complex 2-succinyl-5- synthase: bifunctional a (6S)-5- kinase: FC92_RS09445 biosynthesis phosphodiesterase/ RS09130 S-adenosylhomocysteine β-alanine protein ligase: formate--tetrahydrofolate serine bifunctional an acetoacetyl-[acp] undecaprenyl- all trans-decaprenyl- N-succinyl- a (9Z)-3-oxo- cysteine enolpyruvyl- NaMN FC92_RS00075 methylenetetrahydrofolate formyltetrahydrofolate (R)-pantoate a [phospholipid] 5'-nucleotidase/ a ribonucleoside a 3-oxopimeloyl- a cis-delta17-3- UDP nucleosidase: FC92_RS08185 HMP-PP ligase: FC92_RS02860 hydroxymethyltransferase: glyA folylpolyglutamate DHAP diphospho-N- 2-methoxy-6- DMKH2-13 L,L-2,6- NaMN octadec-9- desulfurase: 6-hydroxy-3- dehydrogenase/ olefinic fatty acid D-glucopyranose 3'-nucleotidase: hypoxanthine PRPP dITP diphosphate [acp] methyl ester oxo-C36:1-[acp] ribonucleotide- FC92_RS03115 5-formyltetrahydrofolate a [lipoyl-carrier synthase/dihydrofolate 3-oxoacyl-[acyl- cyclopropane- acetylmuramoyl- UDP-N-acetyl- 1,4-benzoquinol bifunctional diaminopimelate multifunctional 2',3'- enoyl-[acp] RS07160 FC92_RS03105 cyclohexene- nicotinic acid methylenetetrahydrofolate methenyltetrahydrofolate tetrahydrofolate biosynthesis 6-phosphate FC92_RS08880 bifunctional succinyl- ribonucleotide- 3-oxoacyl-[acyl- 3-oxoacyl-ACP 3-oxoacyl-[acyl- diphosphate a [cysteine desulfurase]- S-ribosyl-L- cyclo-ligase: protein]-N 6 - synthase: FC92_RS06040 carrier-protein] fatty-acyl- L-alanyl-γ-D- α-D-glucosamine xanthine demethylmenaquinone cyclic-nucleotide 2'- non-canonical purine 1-carboxylate mononucleotide reductase [NAD(P) 10 + demethylmenaquinone diaminopimelate diphosphate carrier-protein] reductase: carrier-protein] cyclohydrolase: FC92_RS03410 an N -formyltetrahydrofolate a 5,10-methylenetetrahydrofolate reductase: sn-glycerol NADP -dependent undecaprenyldiphospho- phosphoribosyltransferase: NTP pyrophosphatase, reductase RS04460 S-sulfanyl-[disordered- synthase: homocysteine adenylyltransferase: H]: FC92_RS08225 (7,8-dihydropterin- lipoyl-L-lysine phospholipid xanthosine guanine glutamyl-L-lysyl- methyltransferase/2- methyltransferase/2- desuccinylase: phosphodiesterase/ reductase reductase: FC92_RS02370 reductase: form scaffold a 5,10- FC92_RS00570 a 5,10- FC92_RS02630 3-phosphate synthase: glucose-6- muramoylpentapeptide beta-N- FC92_RS01335 RdgB/HAM1 family: subunit beta: FC92_RS05645 nadD (R)-pantothenate 4-aminobenzoate 6-yl)methyl glutathione- bifunctional bifunctional D-alanyl-D-alanine methoxy-6-polyprenyl-1,4- methoxy-6-polyprenyl-1,4- FC92_RS00965 5'-nucleotidase/ subunit beta: FC92_RS02630 3-oxoacyl-[acyl- FC92_RS02630 protein] complex S-ribosylhomocysteine methylenetetrahydrofolate methenyltetrahydrofolate a tetrahydrofolate 3-oxoacyl-ACP FC92_RS09200 phosphate ditrans,octacisacetylglucosaminyltransferase:- hypoxanthine FC92_RS02810 FC92_RS06670 nicotinate adenine diphosphate glutaredoxin folylpolyglutamate folylpolyglutamate glycerol-3- a [phospholipid] benzoquinol methylase: benzoquinol methylase: 3'-nucleotidase: FC92_RS06670 3-oxoacyl-ACP carrier-protein] 3-oxoacyl-ACP RS11425 cysteine 2-succinyl-5- lyase: FC92_RS06385 reductase: dehydrogenase: guanine deaminase: undecaprenyldiphospho-FC92_RS03175 phosphoribosyltransferase: succinyl- NTP ribonucleoside- dinucleotide bifunctional pantothenate 7,8- redox reactions synthase/dihydrofolate synthase/dihydrofolate phosphate fatty acid containing β FC92_RS04530 FC92_RS04530 FC92_RS08880 reductase: reductase: reductase: desulfurase: enolpyruvoyl- menaquinol-8 biosynthesis FC92_RS02370 FC92_RS02670 FC92_RS04180 N-acetyl-(N-acetyl- -D- FC92_RS08685 6-methoxy-3-methyl- diaminopimelate pyrophosphohydrolase: ribonucleoside- diphosphate methylenetetrahydrofolate kinase: dihydropteroate synthase: FC92_RS06040 synthase: FC92_RS06040 acyltransferase: cyclopropane UDP menaquinol-13 bifunctional FC92_RS02370 FC92_RS02630 FC92_RS02370 RS04105 FC92_RS03105 6-hydroxy-3- L-homocysteine NAD+ GSSG a (3R)-3- 6-phospho glucosaminyl)muramoyl- 2-all-trans-decaprenyl- desuccinylase: FC92_RS07675 diphosphate a (3R)-3- a (3R,9Z)-3- a cis-delta17-3- reductase an S-sulfanyl-[cysteine NAD(+) synthase: dehydrogenase/ FC92_RS09895 bifunctional FC92_RS06240 γ IMP metallophosphatase/ cyclohexene- synthetase, glutathione an N 10 -formyltetrahydrofolate a 5,10-methylenetetrahydrofolate demethylmenaquinol-8 hydroxybutanoyl- a 1-acyl-sn D-glucono- xanthine xanthine L-alanyl- -D-glutamyl-L- 1,4-benzoquinol FC92_RS07210 reductase hydroxypimeloyl- hydroxy-octadec- hydroxyC36:1- subunit alpha: desulfurase]-S- FC92_RS10400 demethylmenaquinol- methenyltetrahydrofolate (R)-4'- folylpolyglutamate L,L- 5'-nucleotidase: dIMP RS08155 1-carboxylate glutamine reductase: bifunctional [acp] -glycerol 3- 1,5-lactone lysyl-D-alanyl-D-alanine succinate subunit alpha: [acp] methyl ester 9-enoyl-[acp] [acp] FC92_RS06675 sulfanyl-[disordered- 2-succinyl-6- dependent: 6 biosynthesis I cyclohydrolase: phosphopantothenate synthase/ diaminopimelate FC92_RS04290 FC92_RS06675 FC92_RS07205 demethylmenaquinone 3-hydroxyacyl- phosphate 6-phosphogluconolactonase: β a 2'- form scaffold hydroxy-2, 4- FC92_RS00570 dihydrofolate di-trans,poly-cis-undecaprenyl -D- dUDP FC92_RS10400 all-trans- glutathione methyltransferase/2- [acyl-carrier- 1-acyl-sn-glycerol- acyl-ACP FC92_RS02325 deoxyribonucleoside RS01410 protein] complex cyclohexadiene- 2-carboxy-1,4- 10 phosphate biosynthesis ribosylnicotinate hexaprenyl an N - synthase: protein] 3-phosphate thioesterase cysteine 1-carboxylate L-cystathionine NAD + naphthoquinol methoxy-6-polyprenyl-1,4- D-gluconate 5'-diphosphate diphosphate 1,4-dihydroxy- formyltetrahydrofolate FC92_RS06040 (2E,6E)-farnesyl dehydratase acyltransferase: pathway urate urate RS04335 desulfurase: synthase: benzoquinol methylase: 6-phosphate cystathionine 2-naphthoate trans, trans-farnesyl 7,8-dihydrofolate diphosphate FC92_RS04530 FabZ: FC92_RS00510 an acyl-[acyl- FC92_RS03105 FC92_RS05640 menaquinol-7 biosynthesis isoprenyl a 1,2-diacyl- a single 2-methoxy-6-all DNA combined with a 3,5,7,9,11,13,15- a (9Z)-3- a [cysteine (1R,6R)-6-hydroxy- gamma-synthase: polyprenyltransferase: diphosphate monoglutamate menaquinol-8 FC92_RS02645 carrier protein] a 2,3,4-saturated a 2,3,4-saturated 2- DMK-12 a 3-oxoicosanoyl- a cis-delta19-3- a reduced transferase: sn-glycerol acyl-ACP stranded DNA trans-heptaprenyl- exogenous DNA to form hepta-oxo- oxohexadec- RS09005 desulfurase]-(S- 2-succinylcyclohexa- FC92_RS00230 FC92_RS05720 biosynthesis 2-carboxy-1,4- fatty acyl-[acp] lysophosphatidate XTP ITP [acp] oxo-C38:1-[acp] dIDP demethylmenaquinol-6 glutaredoxin di-trans,octa-cisFC92_RS00470 a (2E)-but- 3-phosphate thioesterase: exodeoxyribonuclease 1-acyl-sn-glycerol- 1,4-benzoquinolbifunctional bifunctional a recombinationalHolliday junction junction hexadecanoyl-[PKS-acp]aldo/keto 3-oxoacyl-[acyl- 9-enoyl-[acp]3-oxoacyl-[acyl- 3-oxoacyl-[acyl- sulfanyl) -[disordered- 2,4-diene-1- demethylmenaquinol- naphthoquinol non-canonical purine non-canonical purine UDP kinase: RS05200 2 IPP -undecaprenyl 2-enoyl-[acp] FC92_RS06745 D-ribulose UTP and CTP dephosphorylation I VII small subunit: demethylmenaquinone reductase: form scaffold carboxylate cys 9 biosynthesis 1,4-dihydroxy- CDP-diglyceride CO 3-phosphate demethylmenaquinone resolvase RuvX: carrier-protein] carrier-protein] carrier-protein] FC92_RS00270 isopentenyl- diphosphate a fatty acid 2 FC92_RS00560 NTP pyrophosphatase, NTP pyrophosphatase, 2-naphthoate crotonyl-[acyl- synthetase: 5-phosphate acyltransferase: methyltransferase/2- methyltransferase/2- FC92_RS02725 FC92_RS04635 reductase: reductase: reductase: protein] complex o-succinylbenzoate all-trans- diphosphate a 7,8-dihydrofolate undecaprenyl- UTP RdgB/HAM1 family: RdgB/HAM1 family: nucleoside- 2-carboxy-1,4- polyprenyltransferase: carrier-protein] FC92_RS00465 ribulose- exodeoxyribonuclease FC92_RS00510 methoxy-6-polyprenyl-1,4- methoxy-6-polyprenyl-1,4- Holliday junction aldo/keto FC92_RS02630 FC92_RS02630 FC92_RS02630 synthase: nonaprenyl ∆-isomerase: two reduced diphosphatase: demethylmenaquinol- a 2,3,4-saturated FC92_RS02810 FC92_RS02810 diphosphate RS03390 cys RS01280 cys naphthoquinol FC92_RS05720 reductase: a CDP- phosphate 3- VII large subunit: benzoquinol methylase: benzoquinol methylase: resolvase reductase: 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP FC92_RS06765 diphosphate 1,4-dihydroxy- FC92_RS05925 cysteine residues FC92_RS05795 8 biosynthesis I CTP synthase: 1,2-diacyl-sn NTP NTP kinase: folate transformations I demethylmenaquinol-7 di-trans,octa-cis FC92_RS02665 diacylglycerol epimerase: FC92_RS00565 acyl-carrier protein 6-methoxy-3-methyl-2-FC92_RS04530 FC92_RS04530 RecU: recU FC92_RS10125 reductase: reductase: reductase: o-succinylbenzoate 2-naphthoate DMAPP in a protein FC92_RS07050 -glycerol 3- resolution of recombinational 9-hydroxy-3,5,7,11,13,15- pyrophosphohydrolase: pyrophosphohydrolase: FC92_RS09425 a [cysteine desulfurase]- -undecaprenyl 2-carboxy-1,4- FC92_RS03315 a single-stranded a ribonucleoside all-trans-heptaprenyl- menaquinol-12 FC92_RS02370 FC92_RS02370 FC92_RS02370 synthase: polyprenyltransferase: bifunctional CDP-diacylglycerol-- phosphate junction formation hexaoxohexadecanoyl- FC92_RS07675 FC92_RS07675 a (3R)-3- a (3R,9Z)-3- a cis-delta19-3- RS00325 [scaffold protein- a tetrahydrofolate phosphate naphthoquinol a butanoyl-[acp] D-xylulose UMP oligodeoxyribonucleotide 5'-monophosphate 1,4-benzoquinol dITP FC92_RS05635 a tetrahydrofolate FC92_RS05720 farnesyl demethylmenaquinone 1,4-dihydroxy- glycerol-3-phosphate 3- long-chain fatty CTP of two intact strands [PKS-acp] hydroxyicosanoyl- hydroxyhexadec- hydroxyC38:1- (2Fe-2S)] complex 5-phosphate XMP IMP RS05325 demethylmenaquinol-9 pyrophosphate methyltransferase/2- 2-naphthoate phosphatidyltransferase: acid activation bifunctional [acp] 9-enoyl-[acp] [acp] pyridoxal 5'-phosphate salvage I β-ketohexanoyl- 2-succinylbenzoate synthetase: methoxy-6-polyprenyl-1,4- polyprenyltransferase: FC92_RS02380 metallophosphatase/ [acp] synthase: a long-chain phosphoketolase: formate-- FC92_RS05725 benzoquinol methylase: FC92_RS05720 1-(3-sn- 5'-nucleotidase: RS05160 a [co-chaperone]- o-succinylbenzoate- tetrahydrofolate FC92_RS02635 phosphatidyl) fatty acid FC92_RS08050 CMP FC92_RS04290 geranyl FC92_RS04530 pyridoxine pyridoxamine demethylmenaquinol-8 acyl-CoA 5-amino-4- an odd numbered 2-methoxy-6-all a [protein] N-terminal- lysine within a 3- a (7Z)-3- a (5Z)-3- [scaffold protein- -CoA ligase: ligase: 3-oxoacyl-[acyl- -sn-glycerol PRPP DMKH2-11 (R)-lipoate a 3-oxohexacosanoyl- a 3-oxoglutaryl- diphosphate synthetase: bifunctional multifunctional 2',3'- imidazolecarboxyamide straight chain trans-hexaprenyl- formyl-L-methionine gcv protein H oxodocosanoyl- oxohexacos- oxododec- RS07170 (2Fe-2S)] complex FC92_RS09060 FC92_RS02860 carrier-protein] 3-phosphate D-glyceraldehyde [acp] [acp] methyl ester IDP 10 menaquinol-7 pyridoxal kinase: pyridoxal kinase: FC92_RS06220 cyclic-nucleotide 2'- adenine 2,3,4-saturated 1,4-benzoquinol bifunctional peptide lipoate-- [acp] 7-enoyl-[acp] 5-enoyl-[acp] 4-(2'- an N - farnesyl a long-chain 3-phosphate acetyl phosphate metallophosphatase/ bifunctional 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- 3-oxoacyl-ACP SSQ1 chaperone: FC92_RS08530 FC92_RS08530 reductase: phosphatidylglycerophosphatase: phosphodiesterase/ phosphoribosyltransferase: fatty acidacyl-CoA demethylmenaquinone deformylase: protein ligase: UDP kinase: carboxyphenyl)- formyltetrahydrofolate pyrophosphate fatty acyl-CoA 5'-nucleotidase: demethylmenaquinone carrier-protein] carrier-protein] carrier-protein] carrier-protein] reductase: RS05790 FC92_RS00395 FC92_RS02630 FC92_RS09650 type I 5'-nucleotidase/ FC92_RS09120 synthetase: methyltransferase/2- FC92_RS04270 FC92_RS08185 FC92_RS00270 4-oxobutyryl-CoA synthetase: S-adenosyl-L-methionine cycle I pyridoxal pyridoxine pyridoxamine phosphate FC92_RS04290 an odd numbered methyltransferase/2- reductase: reductase: reductase: reductase: FC92_RS02370 a [chaperone-ATP]- a 3-oxohexanoyl- an L-1- glyceraldehyde- 3'-nucleotidase: FC92_RS06220 methoxy-6-polyprenyl-1,4- nucleoside- 1,4-dihydroxy- FC92_RS05725 5'-phosphate 5'-phosphate acetyltransferase: multifunctional 2',3'- adenine straight chain methoxy-6-polyprenyl-1,4- peptide lipoate-- FC92_RS02630 FC92_RS02630 FC92_RS02630 FC92_RS02630 3-oxoacyl-[acyl- [co-chaperone]- [acp] phosphatidyl- 3-phosphate FC92_RS08880 diphosphate AMP benzoquinol methylase: diphosphate RS09855 2-naphthoyl- FC92_RS02245 cyclic-nucleotide 2'- phosphoribosyltransferase: 2,3,4-saturated benzoquinol methylase: deformylase: protein ligase: 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP carrier-protein] [scaffold protein- geranyl pyridoxal kinase: NAD phosphorylation sn-glycerol dehydrogenase: FC92_RS04530 kinase: CoA synthase: bifunctional SAM 3-oxoacyl-[acyl- phosphodiesterase/ FC92_RS07180 fatty acyl CoA 6-methoxy-3-methyl-2-FC92_RS04530 FC92_RS03060 a [glycine-cleavageFC92_RS05500 reductase: reductase: reductase: reductase: reductase: RS01240 (2Fe-2S)] complex transferase: FC92_RS08530 and dephosphorylation FC92_RS09565 acetyl-CoA uridine an N-terminal L- FC92_RS09425 FC92_RS09055 methylenetetrahydrofolate lipoate biosynthesis carrier-protein] biotin-carboxyl carrier 5'-nucleotidase/ AICAR all-trans-hexaprenyl- menaquinol-11 formate complex H protein] FC92_RS02370 FC92_RS02370 FC92_RS02370 FC92_RS02370 FC92_RS02630 bifunctional FC92_RS00555 methionyl-[protein] a (3R)-3- a (3R)-3- a (3R)-3- a (3R,7Z)-3- a (3R,5Z)-3- ITP 1,4-dihydroxy-2- dehydrogenase/ and incorporation II reductase: protein assembly acetaldehyde 3'-nucleotidase: 1,4-benzoquinol N 6 -lipoyl-L-lysine SSQ1 chaperone methylenetetrahydrofolate a (6S)-5- (2E,6E)-farnesyl methionine NAD + 13-DPG hydroxyhexacosanoyl- hydroxydocosanoyl- hydroxyglutaryl- hydroxyhexacos- hydroxydodec- naphthoyl-CoA methenyltetrahydrofolate thioredoxin pathway FC92_RS02630 a [biotin FC92_RS08880 RS05995 ATPase: dehydrogenase/ formyltetrahydrofolate diphosphate adenosyltransferase: PLP gondoate biosynthesis dehydrogenase [acp] [acp] [acp] methyl ester 7-enoyl-[acp] 5-enoyl-[acp] cyclohydrolase: octanoate 3-oxoacyl-ACP carboxyl-carrier (acetylating): FC92_RS00395 methenyltetrahydrofolate FC92_RS05210 lipoate-- thiamine salvage III (anaerobic) phosphoglycerate cytidine RS09750 FC92_RS00570 an oxidized alkaline reductase: protein]-L-lysine FC92_RS09505 cyclohydrolase: 5-formyltetrahydrofolate protein ligase: kinase: glucosyl-(heptosyl) a 2-methoxy-6-all- a ribonucleoside a 3- a (7Z)-3-oxo- a (7Z)-3- a (9Z)-3- a [chaperone- met SAH geranyl thioredoxin phosphatase: NAD kinase: FC92_RS02370 biotin--[acetyl- a [lipoyl-carrier a 3-oxotetracosanoyl- a nucleoside FC92_RS00570 cyclo-ligase: FC92_RS05500 FC92_RS09560 UDP-α-D-galactose -Kdo -lipid A- sn-glycerol trans-polyprenyl- DMKH2-10 (R)-lipoate 2',3'-cyclic oxodocosanoyl- hexadec-7- oxotetradec- oxooctacos- an [2Fe-2S] 2-carboxy-1,4- diphosphate FC92_RS08165 FC92_RS02310 a malonyl-[acp] an oleoyl-[acp] CoA-carboxylase] acetaldehyde 3 2 a myristoyl-[acp] protein]-L-lysine ADP]-[disordered- FC92_RS03410 thiamine a (3R)-3- phosphoglycerate 3-phosphate [acp] diphosphate cluster protein naphthoquinol serine 5'-methylthioadenosine/ lipoate-- biosynthesis [+ 2 isozymes] thiamine (11Z)-3-oxo- ligase: UDP-D-galactose-bisphosphate glycerol-3- 1,4-benzoquinolbifunctional bifunctional lipoate-- phosphate 3-oxoacyl-[acyl- [acp] 3-oxoacyl-[acyl- enoyl-[acp]3-oxoacyl-ACP 7-enoyl-[acp]3-oxoacyl-ACP 9-enoyl-[acp]3-oxoacyl-[acyl- nucleoside- RS08660 form scaffold S-adenosylhomocysteine hydroxyhexanoyl- kinase: alcohol pyrimidine deoxyribonucleotides protein ligase: multifunctional 2',3'- RS04925 protein] complex hydroxymethyltransferase: glyA bifunctional 5-methyltetrahydropteroyltriglutamate- protein ligase: thioredoxin- pyrophosphokinase: [acp] icos-11-enoyl- FC92_RS07000 -(glucosyl) phosphate demethylmenaquinone demethylmenaquinone cyclic-nucleotide 2'- carrier-protein] carrier-protein] reductase: reductase: carrier-protein] diphosphate a 5,10- nucleosidase: IPP [acp] synthase: a [biotin carboxyl- FC92_RS10520 dehydrogenase: dephosphorylation methyltransferase/2- FC92_RS08185 kinase: methylenetetrahydrofolate - homocysteine methyltransferase: a [lipoyl-carrierFC92_RS08185 disulfide NADP + FC92_RS03310 3-hydroxyacyl- lipopolysaccharide-1, 6- acyltransferase: methyltransferase/2- phosphodiesterase/ reductase: reductase: FC92_RS02370 FC92_RS02370 reductase: non-chaperonin methenyltetrahydrofolate FC92_RS03115 farnesyl thiamine carrier protein]-N 3-phospho- FC92_RS09505 NTP pyrophosphohydrolase: dehydrogenase/ FC92_RS01175 protein] N 6 - reductase: [acyl-carrier- an (11Z)-3-FC92_RS02635 D-galactosyltransferase: FC92_RS06240 methoxy-6-polyprenyl-1,4- methoxy-6-polyprenyl-1,4- lipoate-- 5'-nucleotidase/ FC92_RS02630 FC92_RS02630 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- FC92_RS02630 FC92_RS09425 molecular pyrophosphate diphosphate 6 FC92_RS07675 octanoyl-L-lysine FC92_RS06355 oxo-icos-11- -biotinyl-L-lysine D-glycerate FC92_RS10195 1-myristoylglycerol benzoquinol methylase: benzoquinol methylase: protein ligase: UDP kinase: chaperone methenyltetrahydrofolate [+ 2 isozymes] L-homocysteine S-ribosyl-L- synthetase: protein] ethanol dCTP dCMP galactosyl-glucosyl- acyl-carrier protein 3'-nucleotidase: 3-oxoacyl-ACP 3-oxoacyl-ACP carrier-protein] carrier-protein] 3-oxoacyl-ACP RS02375 RS09660 a 5-methyltetrahydrofolate a 5,10- cyclohydrolase: homocysteine dehydratase enoyl-[acp] UDP (heptosyl) -Kdo - 3-phosphate a 6-methoxy-3-methyl-FC92_RS04530 FC92_RS04530 FC92_RS05500 FC92_RS08880 reductase: reductase: reductase: reductase: reductase: FC92_RS00270 ATPase: FC92_RS05725 3-oxoacyl-ACP 3 2 a [lipoyl-carrier protein]- methylenetetrahydrofolate FC92_RS00570 geranyl FabZ: lipid A-bisphosphate 2-all-trans-polyprenyl- menaquinol-10 a ribonucleoside FC92_RS02370 FC92_RS02370 FC92_RS02630 FC92_RS02630 FC92_RS02370 a nucleoside FC92_RS00395 reductase: dUTP diphosphatase: N 6 -lipoyl-L-lysine a (3R)-3- a (3R)-3- a (3R,7Z)-3- a (3R,7Z)-3- a cis-delta9-3- diphosphate a reduced FC92_RS02645 a [biotin carboxyl- 1,4-benzoquinol 3'-phosphate triphosphate an [Fe-S cluster a [disordered- methylenetetrahydrofolate a [lipoyl-carrier FC92_RS02370 2-phospho- FC92_RS06585 hydroxytetracosanoyl- hydroxydocosanoyl- hydroxy-hexadec- hydroxytetradec- hydroxyC28:1- 6 thioredoxin carrier-protein biosynthesis form [Fe-S] cluster reductase [NAD(P) S-ribosylhomocysteine protein]-N - a (2E)-hex- D-glycerate [acp] [acp] 7-enoyl-[acp] 7-enoyl-[acp] [acp] 3-oxoacyl-[acyl- 6 NTP pyrophosphohydrolase: RS07760 RS03120 chaperone]-ATP scaffold protein] lipoyl-L-lysine dimer]-N - H]: FC92_RS08225 lyase: FC92_RS06385 2-enoyl-[acp] carrier-protein] phosphopyruvate FC92_RS07675 biotinyl-L-lysine dUTP dUMP hexanoyl-[acyl- reductase: acetyl-CoA hydratase: a nascent peptidoglycan a peptidoglycan 2-methoxy-6-all 1-stearoyl- adenosine a (3R)-3- a peptide with a (3R,5Z)-3- a (5Z)-3- a (3R,11Z)-3- a cis- sn-glycerol a uracil in DNA acetyl-CoA carrier-protein] FC92_RS02630 carboxylase acetyl-CoA FC92_RS09550 with (L-alanyl-γ-D- with (L-alanyl-γ-D- trans-nonaprenyl- a palmitoyl-[acp] sn-glycerol 2',3'-cyclic hydroxyhexacosanoyl- an N-terminal hydroxy-tetradec- oxotetracos- hydroxyoctadec- a (3R,11Z)-3- phosphoenol vaccenoyl-[acp] 3-phosphate 1,4-benzoquinol uracil-DNA monophosphate L-proline 5-enoyl-[acp] 5-enoyl-[acp] acetyl-CoA Aminoacyl-tRNA Charging reductase: carboxyl carboxylase glutamyl-meso-2,6- glutamyl-meso-2,6- glycerol-3- bifunctional 1-acyl-sn-glycerol-3-phosphate multifunctional 2',3'- [acp] 3-hydroxyacyl- prolyl 3-oxoacyl-ACP 3-oxoacyl-[acyl- 11-enoyl-[acp]3-hydroxyacyl- RS08015 hydroxy-icos- pyruvate 5-hydroxy-CTP 5-hydroxy-CMP glycosylase: carboxylase, RS05475 Amino Acid Biosynthesis FC92_RS02665 transferase biotin carboxylase diaminopimeloyl-D- diaminopimeloyl-D- phosphate demethylmenaquinone 3-phosphate cyclic-nucleotide 2'- [acyl-carrier- aminopeptidase: reductase: carrier-protein] [acyl-carrier- 11-enoyl-[acp] L,D- FC92_RS02240 biotin carboxyl subunit beta: subunit: pyruvate kinase: alanine) tetrapeptide alanine) tetrapeptide acyltransferase: methyltransferase/2- acyltransferase: phosphodiesterase/ protein] FC92_RS04655 FC92_RS02370 reductase: protein] tRNA charging 3-hydroxyacyl- a nascent transpeptidase:peptidoglycan carrier protein: L-asparagine a hexanoyl-[acp] FC92_RS02655 FC92_RS02650 FC92_RS00185 FC92_RS06240 methoxy-6-polyprenyl-1,4- FC92_RS00510 uracil-DNA 5'-nucleotidase/ dehydratase proline 3-oxoacyl-[acyl- FC92_RS02630 dehydratase L-histidine biosynthesis [acyl-carrier- with L,DFC92_RS06885 cross links 1-cis- 1-stearoyl- FC92_RS02640 superpathway of L-methionine biosynthesis (transsulfuration) L-arginine biosynthesis II (acetyl cycle) L-arginine biosynthesis I (via L-ornithine) L-homoserine and L-methionine biosynthesis L-leucine biosynthesis superpathway of L-serine biosynthesis III acetyl-CoA acetyl-CoA D-ala acyl-carrier protein vaccenoylglycerol- benzoquinol methylase: 2-palmitoyl- glycosylase: 3'-nucleotidase: FabZ: iminopeptidase: carrier-protein] 3-oxoacyl-ACP FabZ: RS02850 arginine-- 3-oxoacyl-[acyl- protein] (meso-diaminopimelate acyl-carrier protein and glycine biosynthesis I arg (tRNA-dependent) carboxylase carboxylase pyruvate S-methyl-5'-thioadenosine 3-phosphate 6-methoxy-3-methyl-2-FC92_RS04530 sn-glycerol FC92_RS04455 FC92_RS08880 FC92_RS02645 FC92_RS08570 reductase: reductase: FC92_RS02645 [+ 5 isozymes] RS02895 PRPP tRNA ligase: carrier-protein] dehydratase containing) an apyrimidinic a (2E,11Z)- oxaloacetate N-acetylglutamyl- 3-methyl-2- carboxyl biotin carboxylase degradation IV all-trans-nonaprenyl- 3-phosphate uracil a (2E)-hexacos- FC92_RS02630 FC92_RS02370 malonyl-CoA 3-phospho- FC92_RS02555 an L-arginyl- asp reductase: FabZ: site in DNA 3'-AMP a peptide pro a (5Z)-3-oxo- a (3R,5Z)-3- octadeca-2,11- phosphate Glu asp oxobutanoate2-isopropylmalate transferase subunit: L-lactate D-lactate S-methyl-5'- 1,4-benzoquinol 2-enoyl-[acp] ATP D-glycerate Arg tetradec-5- hydroxytetracos- dienoyl-[acp] aspartate aminotransferase: 3-phosphoglycerate [tRNA ] FC92_RS02630 FC92_RS02645 phosphoribosyltransferase: synthase: Arg subunit alpha: FC92_RS05395 dehydrogenase: dehydrogenase: thioadenosine enoyl-[acp] 5-enoyl-[acp] RS04030 FC92_RS01365 bifunctional a tRNA β-ketooctanoyl- 5'-methylthioadenosine/ FC92_RS09990 aspartate kinase: FC92_RS11030 dehydrogenase: a (2E,11Z)-icosa- FC92_RS02660 FC92_RS08645 FC92_RS06515 RS10960 [+ 2 isozymes] N-acetyl- ornithine (2S)-2- FC92_RS10925 an L-aspartyl- [acp] synthase: 2,11-dienoyl-[acp] a [carboxyl-carrier S-adenosylhomocysteine FC92_RS03215 Asn 1-(5-phospho- bifunctional gamma-glutamyl- acetyltransferase/ isopropylmalate [tRNA ] FC92_RS02635 6 nucleosidase: a [formate C 2-methoxy-6-all 1-stearoyl- guanosine a (3R)-3- a (6Z)-3- phosphoglycerate protein dimer]-N + β-D-ribosyl)-ATP ornithine (2E,11Z)-icosa- FC92_RS03115 a reduced sn-glycerol trans-octaprenyl- hydrogencarbonate H 3'-AMP asp phosphate N-acetylglutamate isopropylmalate dehydrogenase: aspartyl/glutamyl- -carboxybiotinyl- (S)-lactate (R)-lactate SAM acetyltransferase]- a palmitoyl-[acp] a stearoyl-[acp] sn-glycerol 2',3'-cyclic a protein hydroxytetracosanoyl- oxooctadec- met IMP acetyltransferase/ L-aspartyl-4-phosphate a 3-oxooctanoyl- 2,11-dienoyl- acyl-CoA hydrolysis MTR flavodoxin 3-phosphate 1,4-benzoquinol carbonate RS06990 phosphoribosyl- reductase: synthase: isomerase: FC92_RS03555 cysteine-- tRNA(Asn/Gln) L-lysine glycine pyruvate formate- glycerol-3- bifunctional 1-acyl-sn-glycerol-3-phosphate monophosphatemultifunctional 2',3'- ATP-dependent [acp] 3-hydroxyacyl- multifunctional 2',3'- 6-enoyl-[acp]3-oxoacyl-[acyl- bifunctional N-acetylglutamate acetylglutamate cys [acp] [acp] reductase: dehydratase: ATP aspartate kinase: FC92_RS04385 FC92_RS04390 FC92_RS07905 3-phosphooxypyruvate tRNA ligase: amidotransferase lyase 1-activating phosphate demethylmenaquinone 3-phosphate cyclic-nucleotide 2'- Clp protease [acyl-carrier- cyclic-nucleotide 2'- carrier-protein] ornithine RS07155 synthase: kinase: aspartate-semialdehyde 3-oxoacyl-[acyl- FC92_RS02665 a 2,3,4-saturated FC92_RS01025 GMP reductase: diphosphatase: FC92_RS03215 N-acetyl-L- isopropylmalate FC92_RS06605 an L-cysteinyl- subunit C: enzyme: acyltransferase: methyltransferase/2- acyltransferase: phosphodiesterase/ proteolytic protein] phosphodiesterase/ reductase: acetyltransferase/ FC92_RS04390 FC92_RS04395 N-acetyl-L- dehydrogenase: carrier-protein] fatty acyl CoA FC92_RS02335 FC92_RS10025 N-acetyl-L- isomerase: phosphoserine Cys FC92_RS01305 acyl-CoA C1 Compound Utilization carbonate 5'-nucleotidase/ FC92_RS02630 Glu glutamate 5- glutamate FC92_RS02965 [tRNA ] a gondoyl-[acp] pyruvate FC92_RS04950 a [formate C FC92_RS06240 methoxy-6-polyprenyl-1,4- FC92_RS005101-stearoyl-2- 5'-nucleotidase/ subunit: dehydratase N-acetylglutamate β transaminase: Cys reductase: and Assimilation a flavodoxin 1-palmitoylglycerol dehydratase: RS08850 1-(5-phospho- - glutamate semialdehyde FC92_RS07910 a tRNA an L-asparaginyl- thioesterase: fermentation to met 5'-deoxyadenosine acetyltransferase]- acyl-carrier protein benzoquinol methylase: stearoyl-sn 3'-nucleotidase: FC92_RS09585 FabZ: 3'-nucleotidase: 3-oxoacyl-ACP synthase: L-aspartyl-4-phosphate acetylornithine acetylglutamate FC92_RS10920 FC92_RS02630 Alcohol Degradation semiquinone 3-phosphate acyl-carrier protein FC92_RS04595 GMP D-ribosyl)-AMP Asn FC92_RS07545 FC92_RS04530 FC92_RS08880 FC92_RS02645 FC92_RS08880 reductase: FC92_RS04390 kinase: L-aspartate-semialdehyde 2-isopropylmaleate [tRNA ] a 2,3,4-saturated (R)-acetoin II formate assimilation into 5,10- glycin -2-yl radical 6-methoxy-3-methyl- -glycerol 3- a peptide a peptide RS03980 phosphoribosyl- aminotransferase: 3-phospho- 3-oxoacyl-ACP 2-all-trans-octaprenyl- H O CO a (2E)-tetracos- FC92_RS02370 N-acetyl-L- aspartate-semialdehyde FC92_RS04395 aminoacyl-tRNA fatty acid methylenetetrahydrofolate phosphate 2 2 3'-GMP a (3R,6Z)-3- AMP argD homoserine L-serine reductase: pyruvate glycerol and glycerophosphodiester degradation 2-enoyl-[acp] adenosine methionine dehydrogenase: bifunctional isopropylmalate hydrolase: acetolactate 1,4-benzoquinol hydroxyoctadec- cyclohydrolase: N-acetylglutamyl- dehydrogenase: FC92_RS02370 RS05275 FC92_RS02965 ornithine isomerase: FC92_RS08650 synthase AlsS: formate 6-enoyl-[acp] FC92_RS10020 phosphate FC92_RS05560 gln a (3R)-3- a glycerophosphodiester acetyltransferase/ FC92_RS07905 hydroxyoctanoyl- FC92_RS05255 formate-- 1-(5-phospho-β-D-ribosyl)- gln N-acetyl- RS03150 L-aspartate-semialdehyde N-acetylglutamate isopropylmalate an L-glutaminyl- asn [acp] (S)-2-acetolactate glycerol tetrahydrofolate 6-methoxy-2-all- 5-[(5-phosphoribosylamino) L-homoserine a (2R)-2-hydroxy 1-stearoyl- adenine 1518 / guanosine 2251 4-(cytidine 5'- an (11Z)-3- D-ribose 5- synthase: gamma-glutamyl- isomerase: [tRNA Gln ] ligase: a ribonucleoside an aromatic a quinone methylideneamino]imidazole- carbamoyl ser 3-hydroxyacyl- glycerophosphodiester even numbered an oleoyl-[acp] sn-glycerol trans-octaprenyl- 1519 formate diphospho)-2-C- 3'-GMP oxooctadec- phosphate homoserine phosphate a tRNA Gln acetolactate FC92_RS02860 adenine in 16S rRNA triphosphate in 23S rRNA amino acid RS00140 FC92_RS04390 N-acetyl-L- FC92_RS07910 [acyl-carrier- phosphodiesterase: glycerol kinase: 10 1,4-benzoquinone 16S rRNA methyl-D-erythritol 11-enoyl-[acp] NADPH:quinone ribose-5- 4-carboxamide dehydrogenase: phosphate L-lysine biosynthesis II reductase: homoserine O- decarboxylase: an N - straight chain 2,3,4- 1-acyl-sn-glycerol-3-phosphate bifunctional anaerobic 23S rRNA 4-(cytidine 5'- aromatic amino acid multifunctional 2',3'- 3-oxoacyl-[acyl- ornithine (2R,3S)-3- protein] FC92_RS06820 FC92_RS08380 acyl-CoA (adenine(1518)-N(6)/ reductase: phosphate 1-(5-phosphoribosyl) FC92_RS05560 synthase FC92_RS04385 succinyltransferase: serine FC92_RS04365 formyltetrahydrofolate saturated fatty acid 3-phosphate demethylmenaquinone ribonucleoside- (guanosine(2251) diphospho)- aminotransferase: cyclic-nucleotide 2'- carrier-protein] large subunit: hydrogencarbonate isopropylmalate dehydratase synthetase: adenine(1519)-N(6))- triphosphate -2'-O)- phosphodiesterase/ FC92_RS06845 isomerase: RS10950 -5-((5- N-acetyl-L- FC92_RS04570 hydroxymethyltransferase: glyA gln bifunctional a (R)-2-hydroxy even acyltransferase: methyltransferase/2- 2-C-methyl-D- FC92_RS03770 reductase: asp 3-isopropylmalate glutaminyl-tRNA FabZ: (R)-acetoin FC92_RS06220 dimethyltransferase: methyltransferase NADPH:quinone FC92_RS09465 phosphoribosylamino) L-homoserine FC92_RS04860 glutamate 5- carbamoyl homoserine O- sn-glycerol 3-phosphate methylenetetrahydrofolate numbered straight FC92_RS005101-stearoyl-2- methoxy-6-polyprenyl-1,4- reductase: erythritol kinase: 5'-nucleotidase/ FC92_RS02630 RS03035 dehydrogenase: biosynthesis via FC92_RS02645 diphosphate AMP FC92_RS06920 RlmB: aromatic amino acid reductase: [+ 2 isozymes] methylideneamino) carbamoyl aspartate kinase: semialdehyde succinyltransferase: gly Glu dehydrogenase/ chain 2,3,4-saturated acyl-carrier protein oleoyl-sn-glycerol benzoquinol methylase: N 6 -dimethyladenine 1518 FC92_RS02255 2-phospho-4-(cytidineFC92_RS06930 3'-nucleotidase: 3-oxoacyl-ACP phosphate transamidation a 2'-deoxyribonucleoside aminotransferase: D-ribulose imidazole-4- acetylornithine FC92_RS07915 methenyltetrahydrofolate FC92_RS04530 6 1519 FC92_RS06615 FC92_RS08880 FC92_RS06155 phosphate FC92_RS03215 synthase FC92_RS04820 a (2E)-oct- glycerol-3-phosphate fatty acyl CoA 3-phosphate 3-methyl-6-methoxy- /N -dimethyladenine 2-O- 5'-diphospho)-2-C- FC92_RS06950 reductase: 5-phosphate homoserine O- aminotransferase: L-proline an L-glutamyl- 5'-triphosphate 2251 carboxamide isomerase: synthase L-aspartyl- large subunit: (2S)-2-isopropyl- Glu 2-enoyl-[acp] dehydrogenase: cyclohydrolase: 2-octaprenyl-1,4- in 16S rRNA methylguanosine methyl-D-erythritol an aromatic a (3R,11Z)-3-FC92_RS02370 a semiquinone RS01380 succinyltransferase: argD biosynthesis I [tRNA Glu ] Gln guanosine FC92_RS10010 small subunit: 4-phosphate FC92_RS04860 cys O-succinyl-L-homoserine 3-oxosuccinate glutamyl-tRNA Macromolecule Modification FC92_RS08385 FC92_RS00570 benzoquinone in 23S rRNA 2-oxo-acid hydroxyoctadec- RS09830 FC92_RS04570 a tRNA glu octanoyl-[acyl- phosphoribulosylformimino- FC92_RS04855 N-acetyl-L- synthetase: carrier-protein] a 5,10- 11-enoyl-[acp] cys aspartate- carbamoyl DHAP AICAR-phosphate homoserine O- ornithine cystathionine gamma- Glu an L-glutamyl-FC92_RS06600 reductase: tRNA processing methenyltetrahydrofolate carbamoyl L-ornithine semialdehyde phosphate glycerol RS10630 glycerol succinyltransferase: synthase: FC92_RS00230 glutamate Gln phosphate dehydrogenase: acetylornithine synthase 4-methyl-2- [tRNA ] FC92_RS02665 bifunctional a 2'- an [amino group carrier β FC92_RS04820 5-kinase: a nucleoside 3'-UMP -D-fructose 1,6- imidazole glycerol FC92_RS02965 deacetylase: small subunit: oxopentanoate a polycistronic methylenetetrahydrofolate an N-formyl-L- an acyl-[acyl- nicotinate PRPP a ribonucleic acid deoxyribonucleoside [DNA] protein]-C-terminal-γ- a cis-delta11-3- (R)-citramalate AIR RS10805 FC92_RS04580 isoleucine-- aspartyl/ a malonyl-[acp] triphosphate met bisphosphate phosphate FC92_RS01020 FC92_RS04855 L-cystathionine γ-L-glutamyl ile an octanoyl-[acp] tRNA precursor dehydrogenase/ methionylaminoacyl-tRNA carrier protein] nicotinate 5'-triphosphate (L-glutamyl)-L-glutamate multifunctional 2',3'- fructose 1,6- oxo-C30:1-[acp] isopropylmalate 5-(carboxyamino)glycerol RS10495 glycerol L-aspartate- branched-chain tRNA ligase: glutamyl-tRNA peptide deformylase: 3-oxoacyl-[acyl- DNA-directed DNA polymerase aromatic amino acid 3-oxoacyl-[acyl- synthase 5-phosphate Chlorinated methenyltetrahydrofolate phosphoribosyltransferase: acetylglutamate cyclic-nucleotide 2'- bisphosphatase: isomerase: imidazole O-succinyl-L-homoserine semialdehyde carbamoyl amino acid FC92_RS03135 amidotransferase FC92_RS04270 carrier-protein] RNA polymerase III subunit aminotransferase: carrier-protein] subunit HisF: L-ornithine an L-isoleucyl- 3-oxoacyl-[acyl- Compound Degradation cyclohydrolase: FC92_RS10395 kinase: phosphodiesterase/ FC92_RS03050 FC92_RS07905 ribonucleotide aminotransferase: glutamate-5- Ile subunit B: reductase: 4-hydroxy- phosphate cystathionine beta- [tRNA ] carrier-protein] FC92_RS00570 peptide deformylase: reductase: subunit beta: gamma/tau: FC92_RS03770 FC92_RS04395 glycerol RS04490 glycerol FC92_RS10015 ornithine FC92_RS08615 semialdehyde Ile FC92_RS01295 nicotinate 5'-nucleotidase/ fructose- isopropylmalate synthase: RS03195 tetrahydrodipicolinate lyase: FC92_RS09275 a tRNA reductase: 4,5-dichlorocatechol FC92_RS03060 FC92_RS02630 FC92_RS07250 FC92_RS06700 aromatic amino acid an [amino group carrier FC92_RS02630 imidazole glycerol cystathionine gamma- carbamoyltransferase: dehydrogenase: a tRNA precursor a 5,10- phosphoribosyltransferase: 3'-nucleotidase: bisphosphatase isomerase: FC92_RS02475 synthase: ornithine cystathionine beta- [+ 2 isozymes] FC92_RS02630 degradation formate a L-methionylaminoacyl-tRNA acyl-carrier protein a 3-oxoacyl-[acp] [+ 4 isozymes] [+ 8 isozymes] aminotransferase: protein]-C-terminal- 3-oxoacyl-ACP phosphate synthase: FC92_RS00230 FC92_RS04405 leu FC92_RS04585 with a 5' exoribonuclease: methylenetetrahydrofolate FC92_RS06370 γ FC92_RS08880 class III: FC92_RS07910 N5-CAIR glycerol RS10510 glycerol FC92_RS02960 carbamoyltransferase: lyase: FC92_RS04810 an L-glutaminyl- β-ketodecanoyl- a ribonucleic acid [DNA] FC92_RS06950 -(5-phospho-L- reductase: synthase Gln extension and FC92_RS09540 4,5-dichlorobenzene- 4-(methylsulfanyl) uridine FC92_RS08130 (2S,4S)-4- FC92_RS04405 L-glutamate-5- [tRNA ] [acp] synthase: a tRNA precursor NaMN glutamyl)-L-glutamate a cis-delta11-3-FC92_RS02370 citraconate subunit HisH: a long 3' trailer 1,2-diol -2-oxobutanoate RS03630 L-cystathionine hydroxy-2,3,4,5- superpathway semialdehyde leucine-- FC92_RS02635 with a 5' F6P hydroxyC30:1- FC92_RS10005 2-aminoprop-2-enoate leu tetrahydrodipicolinate L-homocysteine of L-threonine tRNA ligase: extension and a [acp] RS00945 4-hydroxy- L-citrulline biosynthesis a 3-oxodecanoyl- RNase BN short 3' extension 2,3-dichloro- FC92_RS05205 an L-leucyl- D-erythro- tetrahydrodipicolinate [acp] ribonuclease: ribonuclease cis,cis-muconate AICAR cystathionine beta- L-citrulline 5-methyltetrahydropteroyltriglutamate- oxaloacetate Leu imidazole-glycerol- argininosuccinate [tRNA ] FC92_RS09540 P protein a 2-methyl a [DNA]-3'- a 5'-phospho- a 1-acyl-sn a 5-aminomethyl-2- a (3R)-3- a [protein]-L- RS05270 lyase: FC92_RS09275 reductase: - homocysteine methyltransferase: aspartate (S)-1-pyrroline- Leu 3-oxoacyl-[acyl- 1-myristoylglycerol + an acyl-[acyl- 3'-cmp a cis-delta13-3- carbonic acid phosphate a tRNA NAD 34 a [protein] Ser/Thr FC92_RS00090 synthase: FC92_RS01175 5-carboxylate carrier-protein] component: a palmitoleoyl-[acp] branched 2,3,4- hydroxyl [DNA] -glycerol 3- thiouridine in tRNA a protein hydroxydocosanoyl- methionine imidazoleglycerol- cystathionine beta- argininosuccinate 2-iminopropanoate aminotransferase: a tRNA 3-phosphate carrier protein] HPr kinase/ multifunctional 2',3'- oxo-C32:1-[acp] carbonate RS08950 FC92_RS06945 reductase: FC92_RS10735 1-acyl-sn-glycerol- saturated fattyacyl-CoA acid DNA 1-acyl-sn-glycerol-phosphate tRNA(5- Xaa-Pro [acp] 3-hydroxyacyl- 3-oxoacyl-[acyl- methionine phosphate lyase: FC92_RS04810 synthase: (S)-2,3,4,5- [+ 2 isozymes] FC92_RS01365 pyrroline-5- precursor with 2-chloro-2-(2-chloro- phosphorylase: cyclic-nucleotide 2'- dehydratase: L-arginino- FC92_RS02630 a tRNA precursor 3-phosphate synthetase: ligase 3-phosphate methylaminomethyl- dipeptidyl- [acyl-carrier- carrier-protein] sulfoxide dehydratase: hisB FC92_RS06945 tetrahydrodipicolinate [+ 2 isozymes] carboxylate a 5' extension 5-oxofuran-2-yl)acetate FC92_RS06340 phosphodiesterase/ FC92_RS01025 succinate with a short acyltransferase: FC92_RS06220 (NAD(+)) acyltransferase: 2-thiouridylate)- peptidase: protein] reductase: reductase A: RS06595 L-arginino- 2,3,4,5- met asp reductase: 3-oxoacyl-ACP a 2-methyl 5'-nucleotidase/ imidazole acetol- L-homocysteine 2-aminoprop-2-enoate valine-- 3' extension FC92_RS00510 LigA: ligA FC92_RS00510 methyltransferase: serine/threonine FC92_RS04660 dehydratase FC92_RS02630 carbonate a protein-L-FC92_RS00310 succinate tetrahydropyridine- argininosuccinate FC92_RS10760 val reductase: ribonuclease 1-myristoyl-2- branched a 1,2-diacyl- 3'-nucleotidase: phosphate tRNA ligase: AMP diphosphate FC92_RS03100 protein kinase: FabZ: 3-oxoacyl-ACP dehydratase: methionine- RS00665 2,6-dicarboxylate N- lyase: pyruvate FC92_RS02370 P protein acyl-carrier protein palmitoleoyl 2,3,4-saturated NMN AMP [DNA] acyl-carrier protein sn-glycerol a 5-methylaminomethyl- a peptide a dipeptide FC92_RS08880 5-methyltetrahydropteroyltriglutamate- argininosuccinate aspartate kinase: FC92_RS03445 an L-valyl- FC92_RS03325 FC92_RS02645 reductase: FC92_RS04595 (S)-S-oxide histidinol- acetyltransferase: FC92_RS06940 pro a (3R)-3- component: 5-chloro-trans phosphatidate fatty acyl-CoA 3-phosphate 2-thiouridine 34 in tRNA - homocysteine methyltransferase: lyase: FC92_RS03215 [tRNA Val ] a [protein] (L-serine/L- cytidine a (2E)-docos- FC92_RS02370 CO H O phosphate FC92_RS10485 hydroxydecanoyl- FC92_RS10735 -dienelactone a cis-delta13-3- 2 2 RS06145 FC92_RS06940 a tRNA Val Carbohydrate Degradation threonine) phosphate 2-enoyl-[acp] transaminase: FC92_RS01175 arg [acp] hydroxyC32:1- 2-iminopropanoate L-2-acetamido-6- L-phenylalanine L-aspartyl- dienelactone FC92_RS04035 [+ 2 isozymes] 3-hydroxyacyl- [acp] arg oxoheptanedioate biosynthesis I 4-phosphate an uncharged hydrolase: D-galactose degradation I (Leloir pathway) RS10705 histidinol- [acyl-carrier- tRNA FC92_RS05490 met superpathway of L-aspartate chorismate aspartate- protein] RS08560 phosphate β 1-cis- a reduced 1-cis- 3-oxo- a (3R,7Z)-3- and L-asparagine biosynthesis semialdehyde L-methionine biosynthesis III alanine-- dehydratase 5-chloromaleylacetate -D-galactose 1-myristoylglycerol a reduced a ribonucleoside a cis-delta15-3- citraconate transaminase: ala a palmitoleoyl-[acp] vaccenoylglycerol- a myristoyl-[acp] L-cystathionine ferredoxin [iron- NADP + H + NADP + H + vaccenoylglycerol- tetracosapentaenoyl- hydroxytetradec- asp pyruvate dehydrogenase: tRNA ligase: FabZ: 3-phosphate adrenodoxin 3'-phosphate oxo-C34:1-[acp] FC92_RS10030 galactose 3-phosphate sulfur] cluster 3-phosphate CoA 7-enoyl-[acp] isopropylmalate N-acetyl-L,L-2,6- Glu FC92_RS02965 FC92_RS02695 FC92_RS02645 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- cystathionine beta- ferredoxin- ferredoxin- multifunctional 2',3'- 1-acyl-sn-glycerol- 3-oxoacyl-[acyl- 3-hydroxyacyl- 3-oxoacyl-[acyl- RS07970 L-histidinol- prephenate an L-alanyl- lipoprotein posttranslational mutarotase: isomerase: aspartate L-alanine diaminopimelate L-homoserine Ala 3-phosphate 3-phosphate lyase: FC92_RS09275 -NADP(+) -NADP(+) cyclic-nucleotide 2'- 3-phosphate carrier-protein] [acyl-carrier- carrier-protein] phosphate L-aspartate- [tRNA ] a (2E)-dec- modification FC92_RS00005 FC92_RS07905 racemase: RS10220 biosynthesis III N-acetyldiaminopimelate aspartate a tRNA Ala (2Z,4Z)-2-chloro- acyltransferase: acyltransferase: cystathionine beta- reductase: reductase: phosphodiesterase/ acyltransferase: reductase: protein] reductase: superpathway of L- semialdehyde 2-enoyl-[acp] FC92_RS08375 histidinol- deacetylase: aminotransferase: a [prolipoprotein]- 3-hydroxyhexa- α-D-galactose FC92_RS005101-cis-vaccenoyl- FC92_RS00510 lyase: FC92_RS04810 an FC92_RS09325oxidized FC92_RS09325 5'-nucleotidase/ 1-cis-vaccenoyl-FC92_RS00510 (3R)-hydroxy-FC92_RS02630 dehydratase FC92_RS02630 isopropylmalate asparagine biosynthesis homoserine dimyristoyl an oxidized isomerase: phosphatase: cys FC92_RS10480 FC92_RS01365 hydrogen sulfide O-acetyl-L- decanoyl-[acyl- L-cysteine 2,4-dienedioate acyl-carrier protein 2-palmitoleoyl acyl-carrier protein L-homocysteine pyruvate NADPH ferredoxin [iron- NADPH 3'-nucleotidase: 2-palmitoleoyl tetracosapentaenoyl- FabZ: 3-oxoacyl-ACP D-aspartate keto- dehydrogenase: homoserine carrier-protein] phosphatidate adrenodoxin FC92_RS08880 FC92_RS07910 RS03540 FC92_RS01205 cysteine desulfurase: L,L- [+ 2 isozymes] prolipoprotein phosphatidate sulfur] cluster phosphatidate CoA FC92_RS02645 reductase: asp phenylpyruvate FC92_RS05560 reductase: a trans-∆ 3 -cis-∆ 7 - (2R,3S)-3- RS06010 [+ 2 isozymes] L-cysteine FC92_RS03105 diaminopimelate O-acetylhomoserine asparagine-- diacylglyceryl a ribonucleoside a cis-delta15-3-FC92_RS02370 methylmalate asp aromatic amino acid aminocarboxypropyltransferase: asn FC92_RS02665 α-D-galactose tetradecenoyl-[acp] biosynthesis I cysteine desulfurase L-homoserine tRNA ligase: transferase: (2Z)-5-chloro-4- α hydroxyC34:1- histidinol diaminopimelate aminotransferase: FC92_RS06435 1-phosphate UDP- -D-glucose asparagine asparagine NifS: FC92_RS03110 epimerase: FC92_RS05890 an L-asparaginyl- a decanoyl-[acp] FC92_RS06345 hydroxyhex-2-enedioate [acp] ala FC92_RS03770 a [prolipoprotein]- histidinol homoserine Asn RS05740 synthase synthase ser FC92_RS03130 aspartate asparagine L-homocysteine [tRNA ] RS00060 aromatic amino acid Asn (S-diacylglyceryl) dehydrogenase: (glutamine- (glutamine- kinase: tRNA 3-oxoacyl-[acyl- 1-stearoyl- a [2-oxoglutarate a 1-alkyl-sn a cis-delta19- a (3R)-3- meso- ammonia-lyase: synthase aminotransferase: -L-cysteine 1-palmitoylglycerol 1-palmitoylglycerol an acyl-[acyl- sn-glycerol 1-myristoylglycerol FC92_RS09995 hydrolyzing): hydrolyzing): FC92_RS05565 carrier-protein] a palmitoleoyl-[acp] a myristoyl-[acp] sn-glycerol a stearoyl-[acp] dehydrogenase E2 protein] reduced riboflavin -glycerol 3- 37-methoxy-38- hydroxyicosanoyl- oxaloacetate a protein diaminopimelate FC92_RS04200 (glutamine- FC92_RS06950 5-methyltetrahydropteroyltriglutamate- 3-phosphate 3-phosphate carrier protein] 3-phosphate 3-phosphate FC92_RS07485 FC92_RS07485 O-phospho- - homocysteine methyltransferase: reductase: 2-maleylacetate 3-phosphate N 6 -dihydrolipoyl-L-lysine NADPH-dependent 1-acyl-sn-glycerol- phosphate methyl-C57:1-[acp] [acp] NAD-dependent histidinal O-acetyl-L-serine diaminopimelate hydrolyzing): signal peptidase 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- glycerol-3- dihydrolipoyl 1-acyl-sn-glycerol- cyclopropane- 3-hydroxyacyl- FC92_RS07485 L-homoserine FC92_RS01175 FC92_RS02630 FMN reductase: 3-phosphate 3-phosphate malic enzyme: lysin: RS04435 RS04005 decarboxylase: fumarate phe II: FC92_RS04825 3-phosphate 3-phosphate 3-phosphate phosphate dehydrogenase: fatty-acyl- [acyl-carrier- histidinol cysteine threonine [+ 2 isozymes] aspartate-- β-ketododecanoyl- UDP-glucose 4- acyltransferase: acyltransferase: acyltransferase: acyltransferase: FC92_RS09680 acyltransferase: acyltransferase: phospholipid protein] FC92_RS07615 FC92_RS01645 asn asn FC92_RS05960 asp an (S-diacyl- epimerase GalE: FC92_RS05495 dehydrogenase: synthase: synthase: tRNA ligase: [acp] synthase: a lipoprotein FC92_RS005101-palmitoyl-2- FC92_RS005101-palmitoyl- FC92_RS00510a 1-stearoyl 2- FC92_RS062401-stearoyl- a [2-oxoglutarate NADPH-dependent 1-myristoyl-2-FC92_RS00510 a 2-acyl-1-alkyl-FC92_RS00510 synthase: dehydratase NAD-dependent FC92_RS09995 asn met FC92_RS02635 sn-glyceryl) FC92_RS09435 FMN reductase: malic enzyme: FC92_RS00235 lys FC92_RS05555 FC92_RS00315 an L-aspartyl- signal peptide 3-oxoadipate acyl-carrier protein palmitoleoyl acyl-carrier protein 2-myristoyl acyl-carrier protein acyl-sn-glycerol acyl-carrier protein sn-glycerol dehydrogenase E2 palmitoleoyl sn-glycerol FC92_RS09200 FabZ: a peptide a 3- -L-cysteinyl- 6 [tRNA asp ] UDP-glucose 4- protein] N -lipoyl-L-lysine FC92_RS08335 phosphatidate 3-phosphate a cis-methoxy- FC92_RS02645 FC92_RS05370 RS11475 phosphatidate phosphatidate 3-phosphate 3-phosphate RS04650 his cys thr tRNA asp oxododecanoyl- [apolipoprotein] epimerase GalE: riboflavin C59-meroacyl-[acp] a (2E)-icos- pyruvate [acp] FC92_RS08140 2-enoyl-[acp] 3-oxoacyl-[acyl- carrier-protein] a peptide an N-acyl-(S- RS02820 reductase: a ring-opened 7- phosphoenol an [HPr]- 1-cis- a uracil 1498 a (3R,5Z)-3- a cis-delta21-39- Nucleoside and Nucleotide Biosynthesis tyrosine-- diacyl-sn-glyceryl) 1-palmitoylglycerol an acyl-[acyl- sn-glycerol DMKH sn-glycerol RS10290 tyr FC92_RS02630 methylguanine in DNA a palmitoyl-[acp] pyruvate L-histidine 3'-dephospho- 2 vaccenoylglycerol- in 16S rRNA hydroxydodec- oxo-40-methyl- ala tRNA ligase: -L-cysteinyl- α-D-glucopyranose 3-phosphate carrier protein] 3-phosphate ATP 3-phosphate 3-oxoacyl-ACP UDP-α-D-galactose DNA- phosphoenolpyruvate- CoA bifunctional 3-phosphate1-acyl-sn-glycerol- 16S rRNA glycerol-3- 5-enoyl-[acp] C59:1-[acp] FC92_RS00895 [lipoprotein] 1-phosphate 1-acyl-sn-glycerol- glycerol-3- dephospho- 3-hydroxyacyl- cyclopropane- alanine superpathway of purine nucleotides de novo biosynthesis I an L-tyrosyl- reductase: formamidopyrimidine 3-phosphate -protein phosphate demethylmenaquinone 3-phosphate (uracil(1498)-N(3))- phosphate [acyl-carrier- fatty-acyl- superpathway of adenosine pyrimidine deoxyribonucleotides de novo biosynthesis I pyrimidine Tyr CoA kinase: racemase: RS01265 superpathway of guanosine [tRNA ] FC92_RS02370 glycosylase: acyltransferase: phosphotransferase: acyltransferase: methyltransferase/2- acyltransferase: methyltransferase: acyltransferase: protein] phospholipid nucleotides de novo biosynthesis II nucleotides de novo biosynthesis II nucleobases salvage II a tRNA Tyr phosphoglucomutase: FC92_RS05065 FC92_RS09245 FC92_RS05060 FC92_RS00355 FC92_RS08625 RS00305 a (3R)-3- 2,6-diamino-4- FC92_RS00510 an [HPr protein]- FC92_RS06240 methoxy-6-polyprenyl-1,4- 1,2-dicis- FC92_RS00510 an N 3 - 1-C16:0-α,ωFC92_RS06240- dehydratase synthase: PRPP UDP CTP FC92_RS06360 a 1-acyl-sn ADP coenzyme A H + hydroxydodecanoyl- an apurinic site dipalmitoyl π benzoquinol methylase: 1498 ribonucleoside- cytosine queuosine biosynthesis hydroxy-5-(N-methyl) acyl-carrier protein N -phospho- pyruvate acyl-carrier protein -glycerol 3- vaccenoyl- methyluracil dicarboxyl-2- FabZ: FC92_RS09200 D-ala IMP asp cytosine deaminase: [acp] phosphoglucomutase: within DNA phosphatidate FC92_RS04530 a cis-keto-C60- IMP diphosphate FC92_RS03655 formamidopyrimidine L-histidine phosphate phosphatidate in 16S rRNA lysophosphatidate FC92_RS02645 amidophosphoribosyltransferase: CDP FC92_RS03565 3-hydroxyacyl- MQH a (2E,5Z)-dodeca- meroacyl-[acp] RS03825 reductase subunit preQ 2 FC92_RS06280 uracil tryptophan-- [acyl-carrier- 0 D-glucopyranose 3,5-dienoyl-[acp] IMP adenylosuccinate alpha: FC92_RS06675 ribonucleoside- a tRNA Trp 7-cyano-7- RS03935 amidophosphoribosyltransferase: bifunctional pyr operon tRNA ligase: protein] 6-phosphate FC92_RS02505 gly dehydrogenase: synthase: ribonucleotide- diphosphate FC92_RS10690 dehydratase deazaguanine FC92_RS08790 FC92_RS07550 transcriptional regulator/uracil an L-tryptophanyl- chitin degradation II (Vibrio) diphosphate reductase subunit Trp reductase: decaprenyl-diphospho-N- UDP-N-acetyl- a 3-methyl- an [amino group carrier protein]- 34 cytidine 2',3'-cyclic a (3R)-3- phosphoribosyltransferase: [tRNA ] FabZ: a polyprenol a guanine 1-palmitoylglycerol sn-glycerol a phosphate RS06415 β reductase subunit alpha: FC92_RS06675 FC92_RS04160 α branched 2,3,4- C-terminal-γ-(L-glutamate 5- UDP-α-D-glucose queuine monophosphate formate CTP D-alanyl-D-alanine 5-phospho- - trp FC92_RS02645 acetylmuramoyl-pentapeptide -D-glucosamine phosphate in tRNA 3-phosphate hydroxypimeloyl- 3-phosphate monoester XMP adenylo-succinate beta: FC92_RS06670 FC92_RS04835 preQ chitin undecaprenyldiphospho- saturated fatty acid semialdehyde-2-yl)-L-glutamate tRNA-guanine(34) multifunctional 2',3'- D-alanyl- D-ribosylamine ribonucleotide- 1 acyl-CoA N-acetyl-gamma- bactoprenol 1-acyl-sn-glycerol- anaerobic [acp] methyl ester3-hydroxyacyl- glycerol-3- alkaline RS10905 dUDP uracil a (2E)-dodec- muramoylpentapeptide beta-N- transglycosylase: cyclic-nucleotide 2'- D-alanine adenylosuccinate diphosphate tRNA-guanine(34) synthetase: glutamyl-phosphate glucosyl 3-phosphate ribonucleoside- [acyl-carrier- phosphate phosphatase: xanthosine-5'- phosphoribosyltransferase: 2-enoyl-[acp] acetylglucosaminyltransferase: FC92_RS02595 phosphodiesterase/ dipeptidase: phosphoribosylamine- lyase: UDP kinase: reductase subunit transglycosylase: FC92_RS06220 reductase: transferase: acyltransferase: triphosphate protein] acyltransferase: FC92_RS08165 RS00200 phosphate:L- FC92_RS00805 dodecanoyl-[acyl- FC92_RS03175 a 3-methyl- 5'-nucleotidase/ FC92_RS02265 -glycine ligase: FC92_RS02480 FC92_RS00270 beta: FC92_RS06670 FC92_RS02595 decaprenyl-pyrophosphoryl- an [amino group carrierFC92_RS04385 protein]- β FC92_RS09845 a queuosine 34 1-palmitoyl-FC92_RS00510 reductase: dehydratase 1-[18- FC92_RS06240 [+ 2 isozymes] glutamine threonine-- carrier-protein] diphosphate AMP branched -D-glucosyl guanine 3'-nucleotidase: FC92_RS02525 nucleoside-diphosphate UMP thr a 7-aminomethyl-7- a chitodextrin UDP (N-acetylglucosamine)-N- C-terminal-γ-(5-phospho- in tRNA 2-myristoyl FC92_RS02255 D-ala FabZ: hydroxyoleyl]- an alcohol amido-ligase dCDP tRNA ligase: reductase: 2,3,4-saturated UDP polyprenyl FC92_RS08880 RS09745 deazaguanosine 34 L-glutamyl)-L-glutamate phosphatidate dCTP FC92_RS02645 AMP kinase: FC92_RS09425 FC92_RS05040 an L-threonyl- acetylmuramyl-(pentapeptide) fatty acyl-CoA phosphate a (2E)- 2-lyso- (AMP-forming): UDP kinase: FC92_RS02665 in tRNA 3'-cmp GAR Thr enoylpimeloyl- phosphatidate RS05410 FC92_RS09900 dUTP FC92_RS00270 [tRNA ] Thr S-adenosylmethionine:tRNA [acp] methyl ester adenylate kinase: dUTP diphosphatase: nucleoside-diphosphate a tRNA a dodecanoyl-[acp] phosphoribosylglycinamide ribosyltransferase- a chitodextrin formyltransferase: GMP FC92_RS07390 FC92_RS06585 kinase: FC92_RS09425 isomerase: FC92_RS02590 RS05340 1915 uridine 2'3'-cyclic FC92_RS02515 34 a pseudouridine a (3R)-3- (3R,5S)-3- NTP dCTP 3-oxoacyl-[acyl- acyl-ACP an epoxyqueuosine seleno-L- a cis- 1-palmitoylglycerol an alkylated DNA 1-palmitoylglycerol formate UTP histidinol RS10605 guanylate kinase: pyrophosphohydrolase: in 23S rRNA ATP H O monophosphate 3-phosphate asp hydroxyglutaryl- hydroxy-1- ADP carrier-protein] thioesterase: in tRNA homocysteine vaccenoyl-[acp] 3-phosphate 2 multifunctional 2',3'- FGAR FC92_RS04670 serine-- 23S rRNA DNA-3- 1-acyl-sn-glycerol- anaerobic [acp] methyl ester pyrroline-5- histidinol FC92_RS07675 ser reductase: FC92_RS06745 5-methyltetrahydropteroyltriglutamate- 1-acyl-sn-glycerol- cyclic-nucleotide 2'- aspartate 3-hydroxyacyl- guanylate kinase: tRNA ligase: (pseudouridine(1915)- methyladenine ATPase: 3-phosphate ribonucleoside- carboxylatepyrroline-5- dehydrogenase: phosphoribosylformylglycinamidine dUMP FC92_RS02630 beta-N- - homocysteine S- 3-phosphate phosphodiesterase/ aminotransferase: [acyl-carrier- FC92_RS03360 FC92_RS05245 an L-seryl- acyltransferase: N(3))-methyltransferase glycosylase: FC92_RS06865 acyltransferase: triphosphate protein] carboxylate FC92_RS09995 RS02770 synthase: FC92_RS02490 superpathway of pyrimidine deoxyribonucleoside salvage β acetylhexosaminidase: methyltransferase: FC92_RS08230 5'-nucleotidase/ FC92_RS01365 F0F1 ATP ribonucleoside- ribonucleotide- thymidylate synthase: ser -ketomeristoyl- laurate a queuosine 34 3 RlmH: FC92_RS08565 FC92_RS03490 FC92_RS00510 reductase: reductase: RS07750 [+ 2 isozymes] [tRNA ] FC92_RS005101-palmitoyl-2- an N - a DNA containing H + phosphate ADP 1-palmitoyl-2- [+ 2 isozymes] dehydratase synthase diphosphate diphosphate ser [acp] synthase: N,N'- FC92_RS06045 N,N',N''- an alkylated 3'-nucleotidase: his GDP FC92_RS00075 2'-deoxycytidine a tRNA in tRNA SeMet methylpseudouridine 1915 an apurinic/ palmitoleoyl FC92_RS02255 FabZ: FC92_RS10760 subunit epsilon: reductase reductase FC92_RS02635 acyl-CoA diacetylchitobiose triacetylchitotriose acyl-carrier protein cis-vaccenoyl nucleobase FC92_RS08880 oxaloacetate trans-4-hydroxy- FGAM dTMP phosphatidate in 23S rRNA apyrimidinic site phosphatidate dUTP FC92_RS02645 L-proline FC92_RS00765 subunit alpha: subunit beta: synthetase: beta-N- 3'-UMP a (2E)- enoylglutaryl- RS03460 phosphoribosylformylglycinamidine [+ 9 isozymes] FC92_RS06675 FC92_RS06670 dTMP kinase: FC92_RS06220 acetylhexosaminidase: RS05870 UDP kinase: ribonucleoside- ribonucleotide- a 3-oxotetradecanoyl- [acp] methyl ester cyclo-ligase: FC92_RS02510 FC92_RS06720 6 FC92_RS06045 FC92_RS00270 diphosphate diphosphate ribonucleotide- ribonucleoside- 2'-deoxyuridine dCMP proline-- [acp] lauroyl-CoA N -L- pro 37 N-acetyl-D- nucleoside- reductase reductase diphosphate diphosphate dTDP tRNA ligase: threonylcarbamoyladenosine 3-oxoacyl-[acyl- N-acetyl-D- 966 (3R)-3- AIR ATP reductase reductase cytidylate kinase: -modified tRNA biosynthesis glucosamine (15Z)- 1-cis- (R)-mevalonate a guanine 1-palmitoylglycerol a (3R,7Z)-3- 2-keto-D- diphosphate subunit alpha: subunit beta: UDP kinase: thymidine kinase: FC92_RS00455 an L-prolyl- carrier-protein] a cis- galactosamine H O diphosphate hydroxypentanoyl- pyrazinamide FC92_RS00120 tetracosenoate vaccenoylglycerol- 2 in 16S rRNA phe hydroxy-hexadec- gluconate RS04330 kinase: FC92_RS06675 FC92_RS06670 subunit beta: subunit alpha: Pro vaccenoyl-[acp] 5-phosphate 3-phosphate RS01580 FC92_RS00270 FC92_RS01760 [tRNA ] reductase: thr acyl-CoA 3-phosphate 6-phosphate manganese- 16S rRNA 1-acyl-sn-glycerol- CoA 7-enoyl-[acp] 2,5-diketo-D- amidase: phosphoribosylaminoimidazole FC92_RS09425 FC92_RS06670 FC92_RS06675 dCDP a tRNA Pro 1-acyl-sn-glycerol- N-acetylglucosamine- aspartate 3-oxoacyl-[acyl- 3-hydroxyacyl- ribonucleotide- ribonucleoside- nucleoside-diphosphate thymidine kinase: thymidine FC92_RS02630 synthetase: dependent inorganic phosphomevalonate (guanine(966)-N(2) gluconic acid FC92_RS09655 carboxylase: FC92_RS01325 threonylcarbamoyl- 3-phosphate 6-phosphate 3-phosphate aminotransferase: carrier-protein] [acyl-carrier- diphosphate diphosphate anaerobic kinase: FC92_RS09425 FC92_RS00825 UDP kinase: 3-oxoacyl-ACP FC92_RS06220 kinase: FC92_RS05920 )-methyltransferase reductase: amidase: stearate biosynthesis AMP synthase: sucrose degradation III (sucrose invertase) acyltransferase: deacetylase: pyrophosphatase: acyltransferase: FC92_RS01365 reductase: protein] 2+ 2+ reductase reductase ribonucleoside- FC92_RS00270 RsmD: FC92_RS08990 Co Co dTTP thymidine kinase: reductase: FC92_RS00810 FC92_RS03885 FC92_RS00510 FC92_RS09665 2+ RS10050 2+ asp triphosphate dADP dUMP II (bacteria and plants) AMP diphosphate (Z)-15- FC92_RS005101,2-dicis- FC92_RS10755 (R)-mevalonate 1-palmitoyl-2- [+ 4 isozymes] FC92_RS02630 dehydratase pyrazine-2- Ni Ni CAIR GTP subunit beta: subunit alpha: FC92_RS02370 L-threonylcarbamoyladenylate D-galactosamine + FC92_RS03015 3-oxopentanoyl- RS08485 FC92_RS01760 nucleoside- sucrose tetracosenoyl-CoA acetate phosphate H an N 2 - cis-vaccenoyl keto- FabZ: [+ 2 isozymes] FC92_RS06670 FC92_RS06675 reductase: phenylalanine- a (3R)-3- acyl-carrier protein vaccenoyl- 6-phosphate diphosphate CoA 2,5-didehydro- carboxylate thymidine kinase: diphosphate 966 phosphatidate phenylpyruvate FC92_RS02645 FC92_RS02255 thymidylate -tRNA ligase a palmitoyl-[acp] phosphatidate methylguanine a (2E,7Z)- D-gluconate FC92_RS00825 kinase: hydroxytetradecanoyl- phosphoribosylaminoimidazolesuccinocarboxamide UDP kinase: synthase: subunit beta: 3-oxo-stearoyl- beta-fructosidase: in 16S rRNA hexadeca-2,7- RS01785 anaerobic FC92_RS09425 [acp] predicted synthase: FC92_RS02485 FC92_RS00270 FC92_RS00075 FC92_RS05835 [acp] synthase: an N 6 -L- FC92_RS07495 dienoyl-[acp] ribonucleoside- dGDP 3-hydroxyacyl- ABC efflux nucleoside- dCTP FC92_RS02635 threonylcarbamoyladenine 37 triphosphate phenylalanine- [acyl-carrier- a 3-oxooctadecanoyl- thiol transporter thiol SAICAR diphosphate protein] [acp] in tRNA β-D-fructofuranose D-glucopyranose (1S,2R)-1- a (3R,5Z)-3- reductase: -tRNA ligase a very-long- salicin 6- 3-oxo- 2+ 2+ of a thiol kinase: phe dehydratase 18-hydroxyoleate linoleate oleate C-(indol-3- ile val a DNA segment (S)-lactate Co RS10120 Co FC92_RS02255 UDP kinase: subunit alpha: 3-oxoacyl-[acyl- chain fatty acid phosphate ser docosapentaenoyl-CoA hydroxy-tetradec- 2+ group 2+ adenylosuccinate FC92_RS09425 glucokinase: recombinase Cu RS07660 Cu FC92_RS05840 an L-phenylalanyl- FabZ: carrier-protein] acyl-CoA acyl-CoA acyl-CoA acyl-CoA 6-phospho-beta- yl)glycerol 3-oxoacyl-[acyl- branched-chain branched-chain 5-enoyl-[acp]3-hydroxyacyl- lactate oxidase: lyase: FC92_RS00270 FC92_RS03395 RecA: Phe FC92_RS02645 fructokinase: synthetase: synthetase: synthetase: synthetase: glucosidase: 3-phosphate tryptophan carrier-protein] FC92_RS02700 Co 2+ RS01445 Co 2+ FC92_RS02480 nucleoside- dTMP [tRNA ] reductase: amino acid amino acid [acyl-carrier- UMP biosynthesis II superpathway of pyrimidine a tRNA Phe FC92_RS06800 D-glucopyranose FC92_RS06220 FC92_RS06220 FC92_RS06220 FC92_RS06220 FC92_RS04140 synthase reductase: FC92_RS02390 lactate oxidase: ammonia RS10185 ammonia diphosphate a (2E)-tetradec- FC92_RS02630 aminotransferase: aminotransferase: protein] AICAR dATP dTMP kinase: nucleobases salvage 2-enoyl-[acp] Glycolysis 6-phosphate 18-hydroxyoleoyl- a very-long-chain [+ 3 isozymes] subunit beta: (5Z,8Z,11Z,14Z,17Z)FC92_RS02630 FC92_RS08615 FC92_RS08615 dehydratase a DNA segment[+ 2 isozymes] FC92_RS04535 kinase: 3-oxoacyl-ACP AMP diphosphate AMP diphosphate AMP diphosphate linoleoyl-CoA diphosphate AMP oleoyl-CoA β-D-glucose FC92_RS07920 (S)-3-methyl-2- 3-methyl-2- + + FC92_RS06720 in reverse acetate Na RS05360 Na FC92_RS09425 uracil myristoyl-[acyl- reductase: glucose-6- CoA fatty acyl-CoA salicyl alcohol 6-phosphate D-glyceraldehyde -3R-hydroxy- FabZ: RS07985 bifunctional gln hydrogencarbonate glycolysis III (from glucose) phosphate 3-phosphate trp docosapentaenoyl-CoA oxopentanoate oxobutanoate FC92_RS02645 orientation phosphoribosylaminoimidazolecarboxamide dTDP bifunctional pyr operon carrier-protein] FC92_RS02370 a (2E,5Z)- methionine-- a (3R)-3- isomerase: formyltransferase/IMP carbamoyl phosphate UDP kinase: transcriptional regulator/uracil met reductase: tetradeca-2,5- RS02705 phosphoribosyltransferase: tRNA ligase: FC92_RS02665 hydroxyoctadecanoyl- D-glucopyranose pgi dienoyl-[acp] cyclohydrolase: FC92_RS02520 synthase large subunit: FC92_RS00270 an L-methionyl- dGTP superpathway of adenosine FC92_RS04835 FC92_RS06905 [acp] an anion RS05375 an anion FC92_RS04860 nucleoside- [elongator glucokinase: F6P FAICAR nucleotides de novo biosynthesis I a myristoyl-[acp] 3-hydroxyacyl- uracil elongator Met α ω arbutin-6- 1402 37 a (3R,6Z)-3- a double- carbamoyl phosphate diphosphate tRNA ] [acyl-carrier- FC92_RS03395 a 2,3,4-saturated , -9Z- a single a ribonucleoside a cytidine a guanine L-cysteate sn-glycerol acrylamide phosphoribosyltransferase: Met 7-hydroxylaurate synthase small subunit: kinase: tRNA protein] chitobiose degradation fatty acid octadecenedioate stranded DNA triphosphate phosphate in 16S rRNA in tRNA 3-phosphate hydroxyoctadec- helix DNA an anion RS03590 an anion RS10775 FC92_RS00805 3-oxoacyl-[acyl- D-glucopyranose acyl-CoA acyl-CoA acyl-CoA 6-phospho-beta- 16S rRNA tRNA (guanine(37) aspartate DNA helicase amidase: bifunctional FC92_RS04855 FC92_RS09425 dehydratase DNA primase: alpha- 6-enoyl-[acp]3-hydroxyacyl- IMP asp UMP carrier-protein] 6-phosphate N,N'- synthetase: synthetase: synthetase: glucosidase: (cytidine(1402)-2'-O) -N(1))- aminotransferase: PcrA: FC92_RS09655 phosphoribosylaminoimidazolecarboxamide reductase: FabZ: FC92_RS01660 glycerophosphate [acyl-carrier- formyltransferase/IMP asp carbamoyl phosphate asp dTTP glucose-6- D-mannose degradation diacetylchitobiose FC92_RS06220 FC92_RS06220 FC92_RS06220 FC92_RS04140 -methyltransferase: methyltransferase: FC92_RS01365 FC92_RS01320 amidase: chloride RS06505 chloride cytidylate kinase: FC92_RS02630 FC92_RS02645 ω-carboxy- DNA primase: oxidase: protein] superpathway of guanosine adenylosuccinate lysine-- phosphate 6'-phosphate [+ 3 isozymes] FC92_RS06740 1 FC92_RS03240 [+ 2 isozymes] [+ 2 isozymes] FC92_RS09665 cyclohydrolase: FC92_RS02520 FC92_RS00120 Lys 7-hydroxylauroyl- a 2,3,4-saturated FC92_RS00245 a 2'-O- an N - FC92_RS08310 dehydratase an unwound RS08550 nucleotides de novo biosynthesis I a tRNA β-ketopalmityl- a (2E)-octadec- isomerase: pgi D-mannopyranose AMP diphosphate AMP diphosphate AMP diphosphate (9Z)-octadec- ssDNA/pppN(pN) β-D-glucose synthase: UMP kinase: tRNA ligase: CoA fatty acyl CoA hydroquinone methylcytidine 1402 methylguanine 37 3-sulfopyruvate DHAP FabZ: double- acrylate aspartate [acp] synthase: 2-enoyl-[acp] 6-phosphate N-monoacetylchitobiose 9-enoyl-CoA hybrid 6-phosphate chloride RS06135 chloride FC92_RS07550 FC92_RS08700 an L-lysyl- n -1 FC92_RS00480 FC92_RS02635 F6P mannose-6- 6'-phosphate in 16S rRNA in tRNA a (2E,6Z)-FC92_RS02645 stranded DNA IMP carbamoyltransferase: [tRNA Lys ] steroyl-[acp] phosphate IMP adenylo-succinate UDP 6-phospho-beta- octadecadienoyl- 2+ 2+ FC92_RS04845 lys a 3-oxohexadecanoyl- reductase: 6-phosphofructokinase: isomerase, class Mg RS02320 Mg glucosidase: [acp] RS07175 UDP kinase: [acp] FC92_RS02665 FC92_RS00190 I: FC92_RS00840 IMP adenylosuccinate FC92_RS04140 FC92_RS00270 F6P IMP adenylosuccinate dehydrogenase: lyase: N-carbamoyl-L-aspartate 3-oxoacyl-[acyl- fatty acid elongation -- saturated β-D-fructose 1,6- Mg 2+ RS06830 Mg 2+ a stearoyl-[acp] [+ 3 isozymes] all-trans- an [amino group carrier protein]-C- a cytidine 1402 guanine 37 (R)-10- a (3R,9Z)-3- dehydrogenase: synthase: FC92_RS02480 nucleoside-diphosphate bisphosphate FMN NAD(P)H H + 2-carboxy-1,4- (R)-mevalonate acetamide FC92_RS08790 carrier-protein] N-acetyl-D- undecaprenyl octanoate Phe β-alanine kinase: FC92_RS09425 terminal-γ-(L-ornithyl)-L-glutamate diphosphate in 16S rRNA in tRNA Hydroxystearate hydroxy-octadec- repressor LexA FC92_RS08790 FC92_RS07550 histidine-- reductase: naphthoquinol acyl-CoA RS04000 dihydroorotase: his acyl-ACP an acetoacetyl-[acp] glucosamine D-glucosamine NADPH-dependent FMN diphosphate 1,4-dihydroxy- acetylornithine 16S rRNA tRNA (guanine(37) oleate hydratase: 9-enoyl-[acp]3-hydroxyacyl- amidase: XMP AMP UTP tRNA ligase: FC92_RS02630 fructose-1,6- synthetase: diphosphomevalonate 4-aminobutyrate Peptide RS01015 Peptide FC92_RS04850 thioesterase: 6-phosphate reductase: FC92_RS09680 2-naphthoate aminotransferase: (cytosine(1402)-N(4) -N(1))- FC92_RS01075 [acyl-carrier- repressor LexA: FC92_RS09665 FC92_RS00320 an L-histidyl- bisphosphate Aromatic Compound Degradation FC92_RS06220 decarboxylase: aminotransferase: adenylo-succinate CTP synthase: 3-oxoacyl-ACP FC92_RS06745 NADPH-dependent FMN polyprenyltransferase: argD )-methyltransferase: methyltransferase: oleate hydratase: protein] FC92_RS00525 amidase: XMP (S)-dihydroorotate [tRNA His ] aldolase, class II: FC92_RS05915 FC92_RS04045 xanthosine-5'- FC92_RS07050 reductase: reductase: FC92_RS08335 an [amino group carrier protein]- 4 FC92_RS03205 1 FC92_RS03240 FC92_RS08780 FC92_RS09655 Peptide RS04540 Peptide adenylate kinase: a tRNA His FC92_RS05720 an N - an N - dehydratase adenylosuccinate stearate FC92_RS07840 protocatechuate degradation + diphosphate AMP octanoyl-CoA γ phosphate:L- FC92_RS02370 NAD(P) FMNH C-terminal- -(L-glutamate 5- IPP 1402 37 3-oxopropanoate oleate cleaved acetate FC92_RS07390 CTP xanthine and fructose degradation 2 DMKH2-11 methylcytidine methylguanine FabZ: RS04640 xanthosine-5'- lyase: glutamine dihydroorotate a (3R)-3- II (ortho-cleavage pathway) semialdehyde-2-yl)-L-glutamate repressor LexA xanthosine salvage acyl-CoA in 16S rRNA in tRNA Phe FC92_RS02645 FC92_RS02480 dehydrogenase B hydroxyhexadecanoyl- a 3-oxoacyl-[acp] a (2E,9Z)- Peptide RS01095 Peptide phosphate:L- amido-ligase synthetase: triose-phosphate β-D-fructofuranose glutamine (AMP-forming): ADP catalytic subunit: [acp] 3-oxoacyl-ACP protocatechuate octadeca-2,9- FC92_RS06220 isomerase: 1-phosphate dienoyl-[acp] amido-ligase AMP FC92_RS09900 FC92_RS04865 xanthosine glycine-- 3-hydroxyacyl- reductase: 1-phosphofructokinase: RS07530 PRPP tRNA ligase [acyl-carrier- FC92_RS09555D-glyceraldehyde predicted (AMP-forming): orotate stearoyl-CoA FC92_RS02370 DHAP β FC92_RS05540 subunit beta: protein] 3-phosphate 3-carboxy-cis -D-fructose 1,6- ABC FC92_RS09900 GMP (R)-4'- all-trans- D-cellobiose an (S)-2- 1-[18-hydroxyoleyl]- an [RNA]-3'- a monocarboxylic a (3R,9Z)-3- Peptide Peptide adenylate kinase: F0F1 ATP ribonucleoside- FC92_RS00250 dehydratase 3-oxoacyl-[acyl- type I ,cis-muconate bisphosphate 2-carboxy-1,4- a nucleoside pyruvate arsenate transporter synthase diphosphate orotate xanthine carrier-protein] phosphopantothenoyl- dodecaprenyl 6'-phosphate halocarboxylate 2-lyso-phosphatidate ribonucleoside- acid amide hydroxyhexadec- ethylphosphate FC92_RS07390 FabZ: glyceraldehyde- naphthoquinol 6-phospho-beta- triphosphate of a peptide GMP guanylate kinase: subunit epsilon: reductase phosphoribosyltransferase: glycine-- β-ketoacyl- reductase: L-cysteine diphosphate 1,4-dihydroxy- HAD family 1-acyl-sn-glycerol- 3'-phosphate amidase: 9-enoyl-[acp]3-hydroxyacyl- alkaline arsenate xanthine FC92_RS02645 3-phosphate glucosidase: NTP RNA 3-phosphate pyruvate oxidase: Peptide RS00680 Peptide RS09270 FC92_RS04670 FC92_RS00765 subunit alpha: FC92_RS04875 tRNA ligase ACP synthase: FC92_RS02630 phosphopantothenoylcysteine 2-naphthoate hydrolase: 3-phosphate FC92_RS09655 [acyl-carrier- phosphatase: reductase phosphoribosyltransferase: gly dehydrogenase: FC92_RS04140 pyrophosphohydrolase: cyclase: FC92_RS04550 guanylate kinase: ADP guanylate kinase: FC92_RS06675 subunit alpha: a (2E)-hexadec- FC92_RS02635 a (3R)-3- (2-carboxy- decarboxylase: FC92_RS03350 polyprenyltransferase: FC92_RS02235 acyltransferase: amidase: protein] FC92_RS07790 (thioredoxin): [+ 9 isozymes] FC92_RS01335 a 2,3,4-saturated FC92_RS09565 FC92_RS07675 FC92_RS00155 FC92_RS04670 FC92_RS03360 FC92_RS00255 2-enoyl-[acp] hydroxyacyl-[acyl- 2,5-dihydro- Detoxification FC92_RS05720 [+ 3 isozymes] [+ 7 isozymes] 1-[18-hydroxyoeoyl]-2-FC92_RS00510 an [RNA]-3'- FC92_RS09665 dehydratase [+ 2 isozymes] FC92_RS03780 ribonucleotide- a glycyl-[tRNA Gly ] fatty acyl-[acp] D-glucopyranose a nucleoside 5'- an (R)-2- Peptide RS07935 Peptide guanylate kinase: orotidine 5'-phosphate carrier protein] 5-oxofuran- 4'-phosphopantetheine D-glucopyranose a halide anion ribonucleoside-2',3'- acetyl phosphate a monocarboxylate arsenite diphosphate superpathway of 5-aminoimidazole palmitoyl-[acyl- 13-DPG DMK-12 6-phosphate monophosphate hydroxyacid [18-hydroxy-lioleoyl]-sn FabZ: ethanol XMP a tRNA Gly 2-yl)-acetate RS00935 FC92_RS03360 ribonucleoside- F0F1 ATP GDP ATP reductase ribonucleotide biosynthesis carrier-protein] 3-hydroxyacyl- reactive oxygen -glycerol 3-phosphate cyclophosphate a (2E,9Z)-FC92_RS02645 orotidine-5'-phosphate gamma- arsenate predicted diphosphate synthase subunit beta: reductase: [acyl-carrier- phosphoglycerate species degradation hexadeca-2,9- GDP decarboxylase: PRPP protein] carboxymuconolactone detoxification ABC reductase subunit epsilon: FC92_RS06670 FC92_RS02665 kinase: decarboxylase: dienoyl-[acp] Peptide Peptide UDP kinase: FC92_RS04870 amidophosphoribosyltransferase: dehydratase superoxide II (glutaredoxin) transporter subunit alpha: FC92_RS00765 ribonucleoside- FC92_RS09560 FC92_RS08740 FC92_RS00270 guanine and FC92_RS06280 FabZ: of a peptide RS10530 FC92_RS06675 [+ 9 isozymes] diphosphate UMP met methionine-- a palmitoyl-[acp] phosphoglycerate arsenate an all-trans- a [protein]- guanosine salvage II amidophosphoribosyltransferase: FC92_RS02645 4-carboxymuconolactone superoxide an (R)-2- an (R)-2- 3-[(3'-methylthio) (indol-3-yl) (2R,3S)-3- sn-glycerol Peptide RS05690 Peptide UDP kinase: ribonucleoside- ribonucleotide- nucleoside- reductase tRNA ligase: arsenate 2-carboxy-1,4- maltotriose π dADP kinase: decarboxylase: dismutase: polyisoprenyl halocarboxylate halocarboxylate acyl-carrier protein phosphoenol propyl]malate acetamide isopropylmalate 3-phosphate N -phospho- FC92_RS00270 diphosphate diphosphate subunit alpha: β FC92_RS02505 pyrimidine FC92_RS06905 an L-methionyl- acyl-ACP 2,3,4-saturated- a trans-2- reductase: a tRNA precursor CTP ATP naphthoquinol alpha-glucosidase: dADP diphosphate 5-phospho- - a 2,3,4-saturated FC92_RS10520 FC92_RS10090 FC92_RS07475 diphosphate HAD family HAD family pyruvate 3-isopropylmalate amidase: isopropylmalate glycerol-3- L-histidine reductase kinase: FC92_RS06675 ribonucleosides salvage I Met thioesterase: fatty-acid-[acp] FC92_RS00730 1,4-dihydroxy- histidine nucleoside- reductase ATP UDP kinase: guanosine D-ribosylamine [initiator tRNA ] enoyl-[acyl- (4,5-dihydro- CCA tRNA hydrolase: FC92_RS01235 hydrolase: ACP S- pyruvate kinase: FC92_RS09655 isomerase: predicted subunit alpha: FC92_RS09425 initiator tRNA Met FC92_RS06745 fatty acyl-[acp] reductase: 3-phospho-D-glycerate hydrogen arsenite 2-naphthoate dehydrogenase: phosphate phosphatase: RS03650 diphosphate subunit beta: ribonucleotide- FC92_RS00270 CMP phosphoribosylamine- cytidine carrier protein] 5-oxofuran- nucleotidyltransferase: FC92_RS02235 alpha-glucosidase: FC92_RS02235 malonyltransferase: FC92_RS00185 amidase: FC92_RS07910 ABC FC92_RS06675 FC92_RS02635 peroxide polyprenyltransferase: FC92_RS07915 acyltransferase: FC92_RS07100Peptide Peptide kinase: FC92_RS06670 diphosphate nucleoside- phosphorylation -glycine ligase: palmitate 2-yl)-acetate a tRNA FC92_RS00085 [+ 6 isozymes] FC92_RS07765 [+ 6 isozymes] FC92_RS02625 FC92_RS09665 isopropylmalate transporter guanine and FC92_RS05720 dATP pyruvate 6-(methylthio)- FC92_RS06240 a [protein]- FC92_RS09425 ribonucleotide- reductase FC92_RS02525 containing a an (S)-2- an (R)-2- isomerase: 1-oleyl-2-lyso- diphosphate CMP DMKH a halide anion D-glucopyranose maltose a halide anion a malonyl-[acp] 2-oxohexanoate (indol-3-yl)acetate L-histidine of a peptide guanosine salvage subunit beta: acyl-CoA 3' CCA end 2 hydroxycarboxylate hydroxyacid phosphatidate diphosphate GTP kinase: guanine cytidylate kinase: 2,3,4-saturated FC92_RS07905 Peptide RS06780 Peptide FC92_RS06670 GAR synthetase: (2S)-2- RS03845 reductase dADP FC92_RS09425 FC92_RS00120 uridine CMP fatty acyl- 2-phospho-D-glycerate arsenite GTP subunit beta: xanthine CDP FC92_RS06220 3-oxoadipate O H O hydroxyl radical isopropylmalate guanosine phosphoribosylglycinamide uridine kinase: [acp]:NAD+ 2 2 FC92_RS06670 phosphoribosyltransferase: phosphopyruvate Peptide RS09790 Peptide UDP kinase: dATP UDP kinase: formyltransferase: FC92_RS05825 palmitoyl-CoA oxidoreductase: FC92_RS00270 dGDP FC92_RS01335 FC92_RS02665 hydratase: FC92_RS00270 FC92_RS02515 phosphatidylglycerophosphate all-trans- an (S)-2- β-D-fructofuranose long chain 3-[(4'-methylthio) a 1-acyl-sn a [protein]- a [protein]- hypoxanthine UMP FC92_RS09550 2-carboxy-1,4- a peptide with a a uridine in tRNA τ RS02405 nucleoside- nucleoside- (1-octadecenoyl(9Z), 2-palmitoyl) tridecaprenyl halocarboxylate 1-phosphate polyphosphate phosphoenol dGDP butyl]malate -glycerol 3- L-histidine N -phospho- dGDP guanine UDP kinase: phosphoribosyltransferase: FGAR naphthoquinol leader sequence diphosphate diphosphate phosphoenolpyruvate diphosphate 1,4-dihydroxy- HAD family signal peptidase fructose-1,6- exopolyphosphatase: pyruvate 3-isopropylmalate tRNA- phosphate1-acyl-sn-glycerol- L-histidine RS09860 FC92_RS00270 FC92_RS08685 histidine kinase: histidine kinase: kinase: phosphoribosylformylglycinamidine Carbohydrate Biosynthesis phosphatidylglycerophosphatase: 2-naphthoate hydrolase: I: FC92_RS06175 bisphosphate FC92_RS10695 pyruvate kinase: dehydrogenase: dihydrouridine 3-phosphate UDP kinase: xanthine FC92_RS03465 phosphatase: FC92_RS09425 nucleoside- FC92_RS09425 synthase: FC92_RS02490 pyruvate kinase: FC92_RS09650 polyprenyltransferase: FC92_RS02235 [+ 2 isozymes] aldolase, class II: exopolyphosphatase: FC92_RS00185 FC92_RS07915 synthase: acyltransferase: FC92_RS00270 phosphoribosyltransferase: diphosphate GMP [+ 6 isozymes] FC92_RS07840 FC92_RS04145 a [protein]- FC92_RS07100 RS09685 [+ 2 isozymes] FC92_RS00185 Carboxylate Degradation 1-oleoyl-2-palmitoyl- FC92_RS05720 a leader sequence a peptide FC92_RS03510 7-(methylthio)-2- a 1-acyl-2-FC92_RS00510 a [protein]- FC92_RS01335 CTP UDP-N-acetyl-D- α an (S)-2- long chain dGTP pyruvate a 5,6-dihydrouridine N-phospho- nucleoside- dATP kinase: dTDP-L-rhamnose UDP-α-D-glucose UDP- -D-glucuronate phosphatidylglycerol DMKH2-13 a halide anion D-glyceraldehyde DHAP oxoheptanoate palmitoyl-sn FGAM glucosamine biosynthesis I pyruvate hydroxycarboxylate polyphosphate in tRNA L-histidine L-histidine RS10165 diphosphate hypoxanthine FC92_RS09425 biosynthesis I biosynthesis I biosynthesis (from acetyl-CoA fermentation to butanoate II -glycerol 3- kinase: phosphoribosyltransferase: D-glucopyranose UDP-glucose) peptidoglycan biosynthesis V (β-lactam resistance) Cell Structure Biosynthesis α-D- D-glucopyranose phosphate FC92_RS09425 FC92_RS08685 dGTP phosphoribosylformylglycinamidine 6-phosphate α RS09185 glucose-6- glucopyranose UDP- -D-glucose acetyl-CoA cyclo-ligase: FC92_RS02510 6-phosphate α phosphate 1-phosphate phosphoglucomutase: UDP-glucose 6- UDP-N-acetyl- -D-glucosamine glucose-1-phosphate all-trans- 967 a [protein]- dGTP GMP FC92_RS06360 dehydrogenase: O-acetyl-L- 2-carboxy-1,4- a 7,8-dihydro-8- a single a cytosine 1-myristoylglycerol 3-[(5'-methylthio) 1-oleyl-2-lyso- RS06890 AIR isomerase: pgi thymidylyltransferase: UDP-N-acetylglucosamine methanethiol decaprenyl wound RNA DNA with lesion N-phospho- F6P phosphoglucomutase: FC92_RS03435 phosphate homoserine naphthoquinol oxoguanine in DNA stranded DNA in 16S rRNA GTP H O 3-phosphate pentyl]malate phosphatidate 1-carboxyvinyltransferase: 2 RNA helicase: excinuclease L-histidine FC92_RS04905 O-acetylhomoserine diphosphate 1,4-dihydroxy- DNA- 16S rRNA 1-acyl-sn-glycerol- 3-isopropylmalate 1-acyl-sn-glycerol- RS08265 dTDP-α-D-glucose α FC92_RS03655 UDP-glucose 6- FC92_RS09635 acetyltransferase: deoxyribonuclease GTPase FC92_RS09590 ABC subunit C: histidine glutamine- -D-glucopyranose aminocarboxypropyltransferase: 2-naphthoate formamidopyrimidine (cytosine(967)-C(5)) 3-phosphate dehydrogenase: 3-phosphate dehydrogenase: FC92_RS02245 IV: FC92_RS00300 CgtA: obgE FC92_RS09075 phosphatase: fructose-6- dTDP-glucose 1-phosphate UDP-N-acetylglucosamine acetoacetyl-CoA FC92_RS06435 polyprenyltransferase: glycosylase: -methyltransferase: acyltransferase: FC92_RS07915 acyltransferase: DNA/RNA Secondary Metabolite Biosynthesis 4,6-dehydratase: α FC92_RS03735 1-carboxyvinyltransferase: FC92_RS05065 FC92_RS03335 [+ 4 isozymes] FC92_RS00510 helicase: [+ 3 isozymes] FC92_RS07100 RS00745 phosphate UTP--glucose- UDP- -D- FC92_RS05720 967 FC92_RS00510 8-(methylthio)- Metabolic Regulator acetate met an apurinic site 7,8-dihydro- a 5'-phosphooligonucleotide a 5-methylcytosine + dioleoyl DNA without a [protein]- transaminase FC92_RS04915 1-phosphate glucuronate FC92_RS00755 acetyl phosphate 3-oxoacyl-[acyl- phosphate GDP H dimyristoyl 2-oxooctanoate FC92_RS06275 RS06525 Biosynthesis carrier-protein] DMKH2-10 within DNA 8-oxoguanine in 16S rRNA phosphatidate phosphatidate lesion L-histidine autoinducer AI-2 biosynthesis I (isomerizing): dTDP-4-dehydro- uridylyltransferase: α an unwound RNA preQ biosynthesis UDP-N-acetyl- -D-glucosamine-enolpyruvate reductase: 0 FC92_RS05755 6-deoxy-α-D- FC92_RS03965 acetate kinase: ppGpp biosynthesis FC92_RS02630 H + RS00780 H + D-glucosamine glucopyranose UDP-N- FC92_RS09500 SAM UDP-α-D-glucose acetylenolpyruvoylglucosamine [+ 3 isozymes] (3R)-3- 6-phosphate dTDP-4- 10 an [apo BCAA dehydrogenase E2 an insertion sequence 3-[(7'-methylthio) (3E)-5-chloro-2- a negatively RS05300 GTP pppGpp PRPP biosynthesis I reductase: FC92_RS10175 hydroxybutanoyl- an N - an L-methionyl- FMNH NADP + maltohexaose an N-modified ADP-D-ribose propionamide a D-hexose dehydrorhamnose 2 6 GTP pyrophosphokinase: phosphoglucosamine acetate CoA formyltetrahydrofolate [initiator tRNA Met ] protein] N -dihydrolipoyl-L-lysine aminoacyl-[tRNA] element IS30 heptyl]malate oxopent-3-enoate supercoiled DNA 3,5-epimerase: NADPH-dependent FMN alpha-glucosidase: ADP-ribose 2-keto-4- DNA amidase: RS05290 FC92_RS02305 mutase: FC92_RS10150 D-ribose 5- methionyl-tRNA dihydrolipoyl aminoacyl-tRNA transposase: 3-isopropylmalate glucokinase: FC92_RS06470 Glu α reductase: FC92_RS08335 FC92_RS01235 pyrophosphatase: pentenoate topoisomerase FC92_RS09655 SAH 7,8- guanosine 3'-diphosphate phosphate ala UDP-N-acetyl- -D-muramate formyltransferase: dehydrogenase: hydrolase: FC92_RS11510 dehydrogenase: FC92_RS03395 GTP pyrophosphokinase: D-glucosamine ribose-phosphate NADPH-dependent FMN alpha-glucosidase: FC92_RS03125 hydratase: IV subunit A: amidase: dihydroneopterin 5'-triphosphate 3'- dTDP-4- an N-formyl- FC92_RS03340 FC92_RS05495 FC92_RS08650 [+ 5 isozymes] FC92_RS07915 RS05075 FC92_RS00345 1-phosphate pyrophosphokinase: reductase: FC92_RS09680 FC92_RS07765 an N-modified an uncharged an insertion FC92_RS00625 FC92_RS06230 FC92_RS09665 5'-methylthioadenosine/ 3'-triphosphate diphosphatase: dehydrorhamnose glutamate racemase: UDP-N-acetylmuramate- crotonyl-CoA pyruvate fermentation L-methionyl- a tetrahydrofolate an [apo BCAA dehydrogenase D-ribofuranose 10-(methylthio)- D-hexose 6- FC92_RS04590 + amino acid tRNA AMP sequence IS30 with 5-chloro-4-hydroxy- S-adenosylhomocysteine bifunctional N- 3,5-epimerase: FC92_RS03755 to acetate IV [initiator tRNA met ] H NADPH FMN D-glucopyranose maltopentaose E2 protein] N 6 -lipoyl-L-lysine 5-phosphate 2-oxodecanoate [+ 3 isozymes] propanoate phosphate FC92_RS00345 ribose-phosphate -L-alanine ligase: integrated transposon 2-oxopentanoate RS00125 nucleosidase: acetylglucosamine- FC92_RS04910 FC92_RS05085 a relaxed DNA FC92_RS03115 1-phosphate pyrophosphokinase: 6-carboxy-5,6,7,8- dTDP-4-dehydro- D-glt pyruvate RS06225 GTP ppGpp uridyltransferase/ β-L-rhamnose FC92_RS06975 UDP-N-acetyl-α-D-muramoyl-L-alanine S-ribosyl-L-homocysteine tetrahydropterin PRPP glucosamine- dTDP-4- butanoyl-CoA a 2-deoxy-D- an apo-[LYS2 L- methyl β-D-glucoside 3-[(6'-methylthio) a [glycerolipid]- (3R)-3-hydroxy- formate 16-hydroxypalmitate a nucleobase maltopentaose O-succinyl-L- 2-hydroxyisobutyramide pyridoxal oxaloacetate 1-phosphate dehydrorhamnose UDP-N-acetylmuramoyl- ribosyl-base methanethiol 2-aminoadipyl- coenzyme A 6-phosphate hexyl]malate oleate stearoyl-CoA RS09280 acetyltransferase: alpha-glucosidase: homoserine S-ribosylhomocysteine GTP pyrophosphokinase: acetyltransferase: reductase: L-alanine--D-glutamate peptidoglycan biosynthesis I (meso-diaminopimelate containing) acyl-CoA synthetase: nucleoside 2- cystathionine carrier-protein] holo-ACP 6-phospho-beta- amidase: 3-isopropylmalate 3-oxoacyl-[acyl- cyclopropane- 3-oxoacyl-[acyl- methylcitrate FC92_RS04945 FC92_RS01235 RS03005 lyase: FC92_RS06385 7-carboxy-7- FC92_RS02305 FC92_RS06970 FC92_RS04920 ligase: FC92_RS03180 FC92_RS06220 deoxyribosyltransferase: gamma-synthase: synthase: glucosidase: FC92_RS09655 dehydrogenase: carrier-protein] fatty-acyl- carrier-protein] synthase: α deazaguanine UDP kinase: GTP pyrophosphokinase: guanosine-3',5'- N-acetyl- -D- dTDP-β-L- UDP-N-acetyl-α-D-glucosamine FC92_RS00985 alpha-glucosidase: FC92_RS00230 FC92_RS08620 FC92_RS04140 amidase: FC92_RS07915 reductase: phospholipid reductase: FC92_RS07955 AI-2 UDP-α-D-galactofuranose lys UDP-N-acetyl-α-D-muramoyl- FC92_RS07765 a holo-[LYS2 L- FC92_RS00270 FC92_RS00345 bis(diphosphate) glucosamine rhamnose butanoate acetyl-CoA formate AMP diphosphate 16-hydroxypalmitoyl-CoA [+ 2 isozymes] [+ 3 isozymes] FC92_RS09665 9-(methylthio)- FC92_RS02630 synthase: FC92_RS02630 (2S,3S)-2- 7-cyano-7- biosynthesis L-alanyl-D-glutamate UDP-N-acetylglucosamine a 2-deoxy-D- succinate met 2-aminoadipyl- 3',5'-ADP β-D-glucose 2-hydroxy-2- 3-oxo- RS07715 nucleoside-diphosphate 3'-diphosphatase: 1-phosphate D-ala a nucleobase D-glucopyranose maltotetraose MeOH 2-oxononanoate 4-pyridoxolactone FC92_RS09200 methylcitrate deazaguanine 1-carboxyvinyltransferase: phosphate ribosyl-base carrier-protein] 6-phosphate methylpropanoate a [phospholipid]- stearoyl-CoA RS01030 synthase: kinase: FC92_RS09425 FC92_RS00345 bifunctional N- UDP-α-D-glucose UDP-N-acetylmuramoyl-L- FC92_RS09635 GDP acetyltransferase: dihydrosterculate FC92_RS04155 acetylglucosamine- UDP-glucose 4-epimerase alanyl-D-glutamate--L-lysine (2R,4S)-2-methyl-2,4- D-alanine--D-alanine UDP-N-acetylglucosamine FC92_RS02245 1-phosphate GalE: FC92_RS09435 ligase: FC92_RS03190 dihydroxydihydrofuran-3-one preQ ligase A: FC92_RS03495 1-carboxyvinyltransferase: RS04185 0 uridyltransferase/ 38- a [lipoyl-carrier UDP-glucose 4-epimerase FC92_RS00755 acetyl phosphate + a uridine 3-oxo- α 18-hydroxystearate FMNH NAD maltoheptaose O-succinyl-L- an acyl- 4-guanidinobutyramide chloramphenicol 6 (R)-mevalonate pyruvate glucosamine- UDP-N-acetyl- -D-muramoyl- 2 coenzyme A protein]-N -[(R) RS05600 GalE: FC92_RS08140 D-alanyl-D-alanine UDP-N-acetyl-α-D- homoserine carrier protein 40 in tRNA icosatrienoyl-CoA 1-phosphate α L-alanyl-γ-D-glutamyl-L-lysine acyl-CoA synthetase: NADPH-dependent FMN alpha-glucosidase: tRNA amidase: 3-oxoacyl-[acyl- -dihydrolipoyl]- UDP- -D-galactose glucosamine-enolpyruvate acetate kinase: cystathionine holo-ACP chloramphenicol mevalonate pyruvate acetyltransferase: FC92_RS06220 reductase: FC92_RS08335 FC92_RS01235 pseudouridine(38- FC92_RS09655 carrier-protein] L-lysine (2R,4S)-2-methyl-2,3,3,4- UDP-galactopyranose FC92_RS09500 gamma-synthase: synthase: acetyltransferase: dihydrolipoyl kinase: carboxylase: FC92_RS06970 UDP-N-acetylmuramoyl- UDP-N- NADPH-dependent FMN alpha-glucosidase: 40) synthase TruA: amidase: reductase: tetrahydroxytetrahydrofuran mutase: FC92_RS05580 [+ 3 isozymes] FC92_RS00230 FC92_RS08620 FC92_RS09495 dehydrogenase: FC92_RS05910 FC92_RS03030 RS01220 UDP-N-acetyl- tripeptide--D-alanyl- acetylenolpyruvoylglucosamine AMP diphosphate 18-hydroxystearoyl-CoA reductase: FC92_RS09680 FC92_RS07765 FC92_RS01440 FC92_RS09665 FC92_RS02630 RS06430 succinate L-homocysteine acyl-carrier protein 3',5'-ADP 38- chloramphenicol FC92_RS05495 (R)-mevalonate α UDP-Galf D- alanine ligase: reductase: FC92_RS10175 + a pseudouridine 3R-hydroxy- a [lipoyl-carrier oxaloacetate -D-glucosamine acetate H NADH FMN D-glucopyranose maltohexaose 4-guanidinobutanoate 3-acetate 5-phosphate FC92_RS09595 40 in tRNA icosatrienoyl-CoA protein]-N 6 - Glu α lipoyl-L-lysine UDP-N-acetyl-α-D-muramoyl-L-alanyl- ala UDP-N-acetyl- -D-muramate RS06120 RS06850 γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine glutamate racemase: an [L-cysteine 516 a [protein]- UDP-N-acetylmuramate- pyruvate decarboxylation to acetyl CoA α a double a cytosine 32 a uridine a double-stranded 2-chloro-trans β-D-fructose 2,6- FC92_RS03755 α-linolenate a (1->4)- -D-glucan desulfurase]-S- a [ThiI sulfur-carrier L-tyrosine (S)-malate -L-alanine ligase: stranded DNA in tRNA cys in 16S rRNA oligonucleotide -dienelactone bisphosphate biotin ATP alpha-glucosidase: sulfanyl-L-cysteine protein]-L-cysteine 16S rRNA phosphate α FC92_RS05085 a [pyruvate dehydrogenase acyl-CoA synthetase: exodeoxyribonuclease tRNA cysteine dienelactone fructose-2,6- fumarate UDP-N-acetyl- -D-muramoyl-L- D-glt pyruvate FC92_RS01235 pseudouridine(516) oligoribonuclease: biotin--[acetyl- protein-tyrosine- γ E2 protein] N 6 -lipoyl-L-lysine FC92_RS06220 V subunit alpha: sulfurtransferase: desulfurase: hydrolase: bisphosphatase: hydratase: RS08785 RS07720 alanyl- -D-glutamyl-L-lysyl-D-alanine UDP-N-acetyl-α-D-muramoyl-L-alanine dehydrogenase alpha-glucosidase: synthase: FC92_RS02685 CoA-carboxylase] phosphatase: Aromatic Compound Biosynthesis FC92_RS03085 FC92_RS03450an [L-cysteine a [ThiIFC92_RS03105 sulfur- FC92_RS05490 FC92_RS04740 FC92_RS10130 α FC92_RS07765 a 2-thiocytosine 32 FC92_RS08365 (acetyl- AMP diphosphate -linolenoyl-CoA desulfurase]- FC92_RS05195 a nucleoside 5'- ligase: UDP-N-acetylmuramoyl- dihydrolipoyl a 5'-phosphooligonucleotide in tRNA ala carrier protein]-S- a 16S rRNA 2-chloromaleylacetate F6P a [protein]- fumarate transferring) pyruvate D-glucopyranose a (1->4)-α-D-glucan L-cysteine monophosphate biotinyl-5'-FC92_RS07000 chorismate biosynthesis dehydrogenase: sulfanyl-L-cysteine pseudouridine 516 L-tyrosine 2,3-dihydroxybenzoate undecaprenyl-diphospho-N-acetylmuramoyl- L-alanine--D-glutamate E1 component RS03705 from 3-dehydroquinate γ FC92_RS05495 adenylate biosynthesis L-alanyl- -D-glutamyl-L-lysyl- D-alanine ligase: FC92_RS03180 subunit alpha: RS06330 undecaprenyldiphospho- FC92_RS05480 3-dehydroquinate meso-diaminopimelate UDP-N-acetyl-α-D-muramoyl- chorismate muramoylpentapeptide beta-N- peptidoglycan peptidoglycan 2-chloro-cis- a [protein]-L- an organic D-mannitol L-alanyl-D-glutamate pristanate glycerophosphoserine an unsulfurated 3-ethylmalate isochorismate acetylglucosaminyltransferase: tetrapeptide, tetrapeptide, VibB coenzyme A cys an acyl phosphate dienelactone methionine hydroperoxide 1-phosphate a [pyruvate dehydrogenase 4'-phosphopantetheine ATP [sulfur carrier] RS08525 synthase: FC92_RS03175 a [pyruvate dehydrogenase acyl-CoA synthetase: glycerophosphodiester glycan chain 1 glycanL,D- chain 2 holo-ACP cysteine dienelactone 3-isopropylmalate peptide- sugar- UDP-N-acetylmuramoyl- D-ala E2 protein] N 6 - 6 RS08175 FC92_RS05650 ditrans,octacis-undecaprenyldiphospho- E2 protein] N -S- FC92_RS06220 pantetheine-phosphate phosphodiesterase: transpeptidase: synthase: desulfurase: acylphosphatase: hydrolase: dehydrogenase: methionine (R)-S- thiol peroxidase: phosphatase: L-alanyl-D-glutamate-- dihydrolipoyl-L-lysine acetyldihydrolipoyl-L-lysine FC92_RS06820 FC92_RS10115 3-dehydroshikimate isochorismate N-acetyl-(N-acetylglucosaminyl)muramoyl- adenylyltransferase: peptidoglycanFC92_RS06885 FC92_RS08620 FC92_RS03105 FC92_RS05860 FC92_RS05490 FC92_RS07915 oxide reductase: FC92_RS06790 2, 6-diaminopimelate D-alanine--D-alanine FC92_RS03010 sn-glycerol L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine AMP diphosphate pristanoyl-CoA ser D-ala DAP-DAP 3',5'-ADP a holo-[VibB aryl- a sulfurated ala a protein-L-FC92_RS04195 ligase: FC92_RS03190 ligase A: FC92_RS03495 3'-dephospho-CoA 3-phosphate a carboxylate 2-chloromaleylacetate 2-oxovalerate an alcohol D-mannitol RS03870 isochorismatase: crosslink carrier protein] [sulfur carrier] methionine- FC92_RS07275 α UDP-N-acetyl- -D-muramoyl-L-alanyl- D-alanyl-D-alanine lipoate (R)-S-oxide RS09020 (2S,3S)-2,3- γ L-malate ditrans,octacis-undecaprenyldiphospho-N -D-glutamyl-meso-2,6-diaminopimelate acetyltransferase: shikimate dihydroxy-2,3- acetyl-CoA degradation II D-serine D-serine -acetyl-(N-acetylglucosaminyl)muramoyl-L- FC92_RS05495 N-acetyl-β-D-glucosamine- a 2,3,4- RS09670 dihydrobenzoate UDP-N-acetylmuramoyl- UDP-N-acetylmuramoyl-L- a dipetide with an N- a [protein] (L-serine/L- D-sorbitol D-ala D-ala alanyl-γ-D-isoglutaminyl-L-lysyl-D-alanine phytenate γ 1,6-anhydro-N- [EntF L-seryl- N-acetyl- trans-dienelactone saturated (3R)-3- 7,8-dihydropterin shikimate kinase: tripeptide--D-alanyl- (S)-malate alanyl- -D-glutamyl-meso-2,6- a tRNA precursor coenzyme A terminal L-aspartate threonine) phosphate 6-phosphate 4-hydroxyphenylpyruvate acetyl-β-D-muramate carrier protein] dipeptidase: L-citrulline hydroxyacyl-CoA FC92_RS05620 D- alanine ligase: NAD-dependent acyl-CoA synthetase: diaminopimeloyl-D-alanineLD- beta-N- ribonuclease Z: holo-ACP protein acetylornithine dienelactone 3-oxoacyl-[acyl- guanine sugar- RS07385 biosynthesis FC92_RS05975 RS10295 FC92_RS09595 malic enzyme: FC92_RS06220 carboxypeptidase: acetylhexosaminidase: synthase: phosphatase: deacetylase: hydrolase: carrier-protein] deaminase: phosphatase: shikimate 3- 2,3- FC92_RS09100 ditrans,octacis-undecaprenyldiphospho- FC92_RS07615 UDP-N-acetyl-α-D-muramoyl-FC92_RS01145 FC92_RS06045 a single-stranded a holoFC92_RS08620-[EntF [+ 4 isozymes] FC92_RS03330 FC92_RS01020 FC92_RS05490 reductase: FC92_RS04180 FC92_RS06790 phosphate dihydroxybenzoate tyr N-acetyl-(N-acetylglucosaminyl) α diphosphate AMP phytenoyl-CoA 1,6-anhydro-N- mature tRNA a proteinogenic UDP-N-acetyl- -D-muramoyl-L- NAD-dependent L-alanyl-γ-D-glutamyl- D-ala GlcNAc oligoribonucleotide 3',5'-ADP L-seryl-carrier asp acetate L-citrulline FC92_RS02630 7,8- D-sorbitol 3-phosphoshikimate 1- γ γ acetyl-β-muramate amino acid a [protein] Ser/Thr 2-maleylacetate a 2,3,4-saturated aromatic amino acid muramoyl-L-alanyl- -D-isoglutaminyl- alanyl- -D-glutamyl-meso-2,6- di-trans,octa-cis-undecaprenyl phosphate malic enzyme: meso-2,6-diaminopimelate protein] dihydrolumazine carboxyvinyltransferase: aminotransferase: N-(β-D-asparatyl)-L-lysyl-D-alanine 3-oxoacyl-CoA RS06265 RS10060 diaminopimeloyl-D-alanyl-D-alanine Amino Acid Degradation FC92_RS05370 FC92_RS05610 FC92_RS06950 pyruvate 5-enolpyruvoyl- aromatic amino acid shikimate 3- L-tryptophan a Chi-site containing 3E,5Z- 2,5-dichloro-trans (2R,3S)-3- a [protein]-L- uridine aminotransferase: L-glutamine a sulfurated glycerophosphoglycerol [EntB aryl- maltose glycocholate cis-dienelactone phosphate ditrans,octacis-undecaprenyldiphospho- degradation IV (via SAM dethiobiotin double stranded RecA tetradecadienoyl-CoA coenzyme A -dienelactone isopropylmalate proline (ω = 180) FC92_RS03770 undecaprenyldiphospho- degradation I [sulfur carrier] glycerophosphodiester carrier protein] alpha-glucosidase: choloylglycine RS04620 chorismate N-acetyl-(N-acetylglucosaminyl) indole-3-lactate) DNA with a blunt end exodeoxyribonuclease acyl-CoA holo-ACP dienelactone 3-isopropylmalate peptidylprolyl dienelactone uridine kinase: RS03265 4-hydroxyphenylpyruvate muramoyl-L-alanyl-γ-D-isoglutaminyl- N-acetylmuramoyl-L-alanyl- biotin synthase: phosphodiesterase: thioesterase: FC92_RS01235 hydrolase: isomerase: FC92_RS05825 synthase: γ-D-glutamyl-meso-2,6- FC92_RS03775 V subunit alpha: synthase: hydrolase: dehydrogenase: hydrolase: N-(β-D-asparaginyl)-L-lysyl-D-alanine trp gln FC92_RS03085 FC92_RS06820 FC92_RS07545 alpha-glucosidase: FC92_RS04205 FC92_RS09330 FC92_RS05605 diaminopimeloyl-D-alanyl-D-alanine an unsulfurated a double stranded DNA (3E,5Z)- FC92_RS08620 FC92_RS05490 FC92_RS07915 FC92_RS05490 aromatic amino acid carbamoyl met 5'-deoxyadenosine biotin sn-glycerol glycerol coenzyme A a holo-[EntB aryl- FC92_RS07765 [+ 2 isozymes] UMP [sulfur carrier] with a RecA protein tetradecadienoate 3',5'-ADP 4-methyl-2- gly cholate chorismate undecaprenyldiphospho- aminotransferase: phosphate 3-phosphate carrier protein] 2,5-dichloromaleylacetate D-glucopyranose a [protein]-L- 2-maleylacetate RS09080 L-aspartate loaded 3' overhang oxopentanoate ω muramoylpentapeptide beta-N- FC92_RS03770 synthase proline ( = 0) RS00670 acetylglucosaminyltransferase: degradation I a peptidoglycan dimer (tetrapeptide) aromatic amino acid large subunit: FC92_RS03175 FC92_RS04860 aminotransferase: RNase III mRNA icosapentaenoyl- a dipeptide with a (3R)-3-hydroxy-2-oxo- phosphoenol asp decanoate c-di-GMP sec D-threo-isocitrate lipid II (meso diaminopimelate containing) FC92_RS06950 [+ 6 isozymes] DL-allothreonine processing C-terminal L-proline 3-sulfinoalanine a tRNA ser RS02600 (indol-3- aspartate CoA 4 phosphooxybutanoate pyruvate yl)pyruvate Glu acyl-CoA synthetase: substrate acyl-CoA c-di-GMP Xaa-Pro phosphoserine cysteine sulfinate serine-- isocitrate RS10210 a peptidoglycan tetramer with L,D aminotransferase: serine ribonuclease III: pyruvate kinase: FC92_RS06220 thioesterase: phosphodiesterase: dipeptidase: transaminase: desulfinase: tRNA ligase: dehydrogenase cross-links (L-lys-D-Asn-L-Lys) FC92_RS01365 hydroxymethyltransferase: glyA FC92_RS03275 FC92_RS00185 RNase III FC92_RS07545 FC92_RS03535 FC92_RS00590 FC92_RS10920 FC92_RS00715 FC92_RS05245 (NADP(+)): [+ 2 isozymes] gly acetaldehyde diphosphate AMP decanoyl-CoA an mRNA fragment processing coenzyme A icosapentaenoate a proteinogenic pro 4-phosphooxy- an L-seryl- FC92_RS07950 RS07450 oxaloacetate linear dimeric GMP sulfite ala sec pyruvate product mRNA amino acid L-threonine [tRNA ] 2-oxoglutarate a peptidoglycan with (L-alanyl-γ-D-glutamyl- indole-3-lactate RS03925 L-lysyl-D-alanyl-D-alanine) pentapeptide a nascent peptidoglycan with (L- an N-acetyl-β- α RS05425 Amine and Polyamine Degradation sn-glycero-3- an L-cysteinyl- -D-glucopyranose (S)-4-hydroxy- a supercoiled alanyl-γ-D-glutamyl-meso-2,6- D-hexosaminide icosapentaenoate coenzyme A glycochenodeoxycholate a RNA-DNA hybrid 2-phosphoglycolate phosphoethanolamine [tRNA Cys ] 1-phosphate 2-oxopentanoate duplex DNA γ glycerophosphodiester beta-N- acyl-CoA choloylglycine ribonuclease HII: 2-keto-4- a peptidoglycan with (L-alanyl- -D-glutamyl- diaminopimeloyl-D-alanine)LD-carboxypeptidase: tetrapeptide phosphoglycolate aminoacyl-tRNA sugar- helicase: RS02445 N-acetylglucosamine phosphodiesterase: acetylhexosaminidase: synthetase: hydrolase: FC92_RS00035 pentenoate L-lysyl-D-alanyl-D-alanine) pentapeptide 4-aminobutanoate FC92_RS01145 phosphatase: hydrolase: phosphatase: FC92_RS00995 degradation I a nascent peptidoglycan with FC92_RS06820 FC92_RS06045 FC92_RS06220 FC92_RS04205 [+ 2 isozymes] hydratase: degradation III an N-acetyl-β- FC92_RS00330 FC92_RS08650 FC92_RS06790 [+ 4 isozymes] RS09715 N-acetyl-D- D-ala (L-alanyl-γ-D-glutamyl-meso- sn-glycerol an alcohol icosapentaenoyl- a nucleoside 5'- FC92_RS00625 ethanolamine D-hexosamine gly chenodeoxycholate DNA a tRNA Cys cys D-glucopyranose a single glucosamine 2,6-diaminopimelate) tripeptide 3-phosphate CoA monophosphate glycolate 2-oxopent- 4-aminobutanoate 4-enoate stranded DNA RS10740 6-phosphateN-acetylglucosamine- 4-aminobutyrate 6-phosphate aminotransferase: RS08795 deacetylase: FC92_RS04045 N-acetyl-D-glucosaminyl-N- (25S)-3- succinate 2-succinylbenzoate coenzyme A chitin O-ureido-L- (+)-7-epi- H O stearoyl-CoA H O a sugar phosphate citrate methylglyoxal D-glucosamineFC92_RS10755 acetylmuramoyl-L-alanyl-D-glutamyl- O-acetyl-L-serine hydrogen selenide oxocholest- coenzyme A asp jasmonoyl-CoA 2 2 semialdehyde beta-N- homoserine 6-phosphate 6-carboxy-L-lysyl-D-alanine o-succinylbenzoate- 4-en-26-oate acyl-CoA argininosuccinate acyl-CoA acyl-CoA sugar- aconitate glyoxalase: RS06795 succinate- LD-carboxypeptidase: cysteine synthase: -CoA ligase: acetylhexosaminidase: thioesterase: thioesterase: FC92_RS01145 FC92_RS00235 synthetase: synthase: phosphatase: hydratase: FC92_RS04645 RS01455 semialdehyde N-acetyl-D-glucosaminyl-N- FC92_RS09060 FC92_RS06045 FC92_RS06220 FC92_RS07545 FC92_RS07545 FC92_RS06790 4-(2'-carboxyphenyl) N-acetyl-D- (25S)-3- FC92_RS06945 (+)-7-epi- FC92_RS07960 [+ 3 isozymes] dehydrogenase: D-ala acetylmuramoyl-L-alanyl-D- acetate L-selenocysteine chitin oxocholest-4- stearate α -4-oxobutyryl-CoA glucosamine canavaninosuccinate jasmonate a sugar D-threo-isocitrate (R)-lactate -D-glucosamine FC92_RS04040 glutamyl-6-carboxy-L-lysine en-26-oyl-CoA 6-phosphate RS05955 succinate RS02440 glucosamine- a DNA containing 3-[(3aS,4S,7aS)-7a-methyl- L-alanyl-γ-D-glutamyl-meso- 34 γ β-L-galactose 6-phosphate 7,8- a cytidine dihomo - H O D-firefly H O a double α-D-ribofuranose urea degradation I 1,5-dioxo-octahydro-1H coenzyme A an apurinic/ propanoyl-CoA phosphate lys 2 2 deaminase: 2,6-diaminopimeloyl-D-alanine dihydroneopterin in tRNA Ile2 linolenoyl-CoA luciferyl-CoA 1-phosphate stranded DNA -inden-4-yl]propanoate LD-carboxypeptidase: dihydroneopterin apyrimidinic site phosphate acyl-CoA acyl-CoA FC92_RS06995 acyl-CoA synthetase: endonuclease III: tRNA(Ile)-lysidine sugar- DNA gyrase ribokinase: RS10980 urea FC92_RS01145 aldolase: acyltransferase: synthetase: thioesterase: thioesterase: phosphatase: subunit A: RS00350 3-[(3aS,4S,7aS)-7a-methyl-FC92_RS06220 FC92_RS05880 FC92_RS08830 F6P L-alanyl-γ-D-glutamyl- FC92_RS08180 a 3'-terminal a 5'-phospho- FC92_RS03285 FC92_RS08680 FC92_RS07545 FC92_RS07545 FC92_RS06790 FC92_RS07590 1,5-dioxo-octahydro-1H- D-ala 6-(hydroxymethyl) 34 di-homo-γ- meso-diaminopimelate glycolaldehyde unsaturated sugar [DNA] propanoyl a lysidine D-firefly luciferin a negatively α-D-ribose Ile2 L-galactopyranose inden-4-yl]propanoyl-CoA -7,8-dihydropterin phosphate in tRNA linolenate 5-phosphate urea-1-carboxylate supercoiled DNA citrate RS07610 citrate RS08540 allophanate GDP-α-D- a sugar RS07515 a sugar hydrolase: 7,8-dihydroneopterin a peptidoglycan 7,8- canavaninosuccinate phosphoenol sulfite pyruvate 2-oxobutanoate a long-chain H O an acyl-CoA H O 2-deoxy-D-ribose 5-methylcytosine FC92_RS05380 3'-triphosphate dihydromonapterin pyruvate fatty acyl-CoA 2 2 mannose lysozyme: dihydroneopterin argininosuccinate phosphosulfolactate acetolactate acyl-CoA acyl-CoA GDP-mannose 6-pyruvoyltetrahydropterin ribokinase: cytosine ammonium FC92_RS01340 aldolase: lyase: FC92_RS06940 synthase: synthase AlsS: thioesterase: thioesterase: 4,6-dehydratase: predicted RS06335 Inorganic Nutrient Metabolism synthase: FC92_RS03615 a N-acetylmuramoyl- FC92_RS08830 deaminase: (6R)-6-pyruvoyl- N-acetyl-D- FC92_RS08180 FC92_RS09725 FC92_RS05255 FC92_RS07545 FC92_RS07545 FC92_RS03670 ABC PPP pentapeptide- 6-(hydroxymethyl) fumarate L-canavanine (2R)-phospho- (S)-2-aceto-2- a long-chain FC92_RS03565 a sugar a sugar i 5,6,7,8-tetrahydropterin glucosamine glycolaldehyde a carboxylate GDP-4-dehydro- 2-deoxy-D-ribose transporter urea cycle diphosphoundecaprenol thymine -7,8-dihydropterin 3-sulfolactate hydroxybutanoate fatty acid α-D-rhamnose 5-phosphate of a sugar RS03760 RS10360 ammonium β a 5S rRNA RNase R degradation a -D- UTP D-glucopyranose acetoacetyl-CoA H O acetyl-CoA a tripeptide palmitoyl-CoA H O lauroyl-CoA H O oleoyl-CoA H O 5-fluorocytosine 2 precursor substrate RNA fructofuranoside 2 2 2 6-phosphate carbamoyl beta-fructosidase: NTP arg hydroxymethylglutaryl-CoA ribonuclease M5: ribonuclease R: peptidase T: acyl-CoA acyl-CoA acyl-CoA sugar- cytosine phosphate FC92_RS07495 pyrophosphohydrolase: RS08045 synthase synthase: FC92_RS03530 FC92_RS06915 FC92_RS09540 FC92_RS00210 thioesterase: thioesterase: thioesterase: phosphatase: deaminase: β FC92_RS07675 RS03785 a double-stranded a nucleoside 5'- a glycoside -D-fructofuranose a proteinogenic FC92_RS07545 FC92_RS07545 FC92_RS07545 FC92_RS06790 FC92_RS03565 argininosuccinate large subunit: HMG-CoA a mature 5S-rRNA a diribonucleotide a dipeptide UMP oligonucleotide monophosphate amino acid palmitate laurate oleate 5-fluorouracil lyase: FC92_RS04860 D-glucopyranose FC92_RS06940 carbamoyl RS06540 phosphate L-arginino- synthase RS03795 L-ornithine succinate small subunit: FC92_RS04855 RS00050 carbamoyl ornithine phosphate RS03995 argininosuccinate carbamoyltransferase: synthase: FC92_RS04405 RS00620 FC92_RS06945 L-citrulline arg RS04055 arg N-acetyl-α-D- D-cellobiose galactosamine arg RS01275 arg RS02920 6'- D-fructose D-mannose 1-phosphate phosphate an L- a branched- a branched- a branched- a β- phosphate D-cellobiose a sulfonate 1-phosphate an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino 6-phosphate glutamate a polyisoprenyl- a pyrimidine Ni 2+ sorbose 1- a sugar 6- a sugar 6- a sugar 6- D-fructose D-fructose D-fructose D-fructose chain chain chain sucrose 6 G sucrose 6 G lactose 6'- glutamate D-mannose gln a nicotinamide a nicotinamide glucoside 6- 9H-purine- D-glucose 6- lactose 6'-phosphate 6'- bacitracin a nucleotide D-gluconate acid acid acid acid acid acid acid acid acid acid 4-aminobutanoate 4-aminobutanoate (RS)-malate (RS)-malate teichoic acid nucleoside an oligopeptide phosphate phosphate phosphate phosphate a phospholipid a phospholipid 1-phosphate 1-phosphate 1-phosphate 1-phosphate amino acid amino acid amino acid -phosphate -phosphate phosphate 6-phosphate mononucleotide mononucleotide phosphate 2,6,8-triol phosphate D-cellobiose 6'-phosphate phosphate predicted predicted predicted PEP-driven predicted predicted predicted PEP-driven PEP-driven transporter PEP-driven ABC ABC RS01820 RS01155 RS09260 RS09350 RS06055 RS05285 RS05120 RS05570 RS09000 RS09380 RS05345 RS03930 RS07990 RS08920 RS00400 RS09140 RS04020 RS10140 RS08980 RS04130 RS09460 RS04890 RS01060 transporter RS04300 RS05680 RS05545 RS01270 RS05800 RS04665 RS04690 RS02450 RS06450 RS05595 RS06260 RS07895 RS03575 RS08220 RS06425 RS06775 RS06815 RS03910 RS01055 RS04060 transporter RS01065 GlnQ RS06445 RS05250 RS07570 RS01945 RS01350 RS06550 RS07465 RS01330 of N-acetyl- RS02330 RS04125 transporter RS04135 transporter transporter RS06640 RS04075 RS00515 RS07795 RS06210 RS08845 RS04785 RS03000 RS06840 of D-fructose of D-mannose alpha-D- of D- of a sulfonate of phosphate galactosamine cellobiose a phospholipid a phospholipid

a polyisoprenyl- a pyrimidine 2+ a branched- a branched- a branched- N-acetyl-α-D- lactose Ni L-sorbose D-gluconate a sugar a sugar a sugar D-fructose D-fructose D-fructose D-fructose D-fructose an amino an amino an amino an amino an amino an amino an amino an amino an amino an amino sucrose sucrose lactose D-mannose D-mannose glutamate a nicotinamide a nicotinamide a β-glucoside 9H-purine- D-glucose D-cellobiose D-cellobiose bacitracin teichoic acid nucleoside a nucleotide chain chain chain glutamate gln 4-aminobutanoate (RS)-malate (RS)-malate galactosamine D-cellobiose a sulfonate phosphate an oligopeptide acid acid acid acid acid acid acid acid acid acid 4-aminobutanoate mononucleotide mononucleotide 2,6,8-triol amino acid amino acid amino acid This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.