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Rph3a (NM 011286) Mouse Tagged ORF Clone – MR210001 | Origene

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Rph3a (NM 011286) Mouse Tagged ORF Clone – MR210001 | Origene OriGene Technologies, Inc. 9620 Medical Center Drive, Ste 200 Rockville, MD 20850, US Phone: +1-888-267-4436 [email protected] EU: [email protected] CN: [email protected] Product datasheet for MR210001 Rph3a (NM_011286) Mouse Tagged ORF Clone Product data: Product Type: Expression Plasmids Product Name: Rph3a (NM_011286) Mouse Tagged ORF Clone Tag: Myc-DDK Symbol: Rph3a Synonyms: 2900002P20Rik; AU022689; AW108370 Vector: pCMV6-Entry (PS100001) E. coli Selection: Kanamycin (25 ug/mL) Cell Selection: Neomycin This product is to be used for laboratory only. Not for diagnostic or therapeutic use. View online » ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 1 / 5 Rph3a (NM_011286) Mouse Tagged ORF Clone – MR210001 ORF Nucleotide >MR210001 ORF sequence Sequence: Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGACTGACACTGTGGTGAACCGATGGATGTACCCTGGTGATGGCCCTCTGCAGTCAAATGACAAGGAAC AGCTGCAGGCAGGATGGTCCGTCCATCCTGGAGCACAGACCGACAGGCAGAGGAAGCAGGAAGAACTGAC AGACGAGGAGAAGGAGATCATCAACAGAGTGATTGCTCGGGCAGAGAAGATGGAAGCCATGGAACAGGAA CGCATTGGGCGCCTGGTGGACCGTCTGGAGACCATGAGGAAGAATGTGGCTGGAGATGGCGTGAACCGCT GCATTCTGTGTGGGGAACAGCTGGGTATGCTGGGCTCGGCCTGTGTCGTGTGTGAAGACTGTAAGAAGAA TGTCTGCACCAAGTGTGGGGTTGAGACCTCCAACAACCGTCCGCATCCGGTATGGCTCTGCAAGATCTGC CTTGAGCAGAGAGAGGTCTGGAAGCGCTCAGGAGCATGGTTCTTCAAAGGTTTCCCCAAGCAGGTCCTTC CACAGCCCATGCCTATAAAGAAGACCAAGCCCCAGCAGCCTGCTGGTGAACCGGCCACCCAGGAGCAGCC TACACCTGAGTCCAGGCATCCAGCCAGGGCTCCAGCTCGAGGTGACATGGAGGACAGGAGGCCCCCAGGG CAGAAGCCAGGCCCTGACCTCACCTCTGCTCCTGGGAGAGGAAGCCATGGGCCTCCCACGCGTAGGGCCT CTGAGGCACGGATGAGTACAGCCGCCCGGGATTCTGAGGGCTGGGACCATGCCCATGGTGGGGGTACTGG AGACACCAGCCGTAGCCCAGCAGGTTTGAGGCGAGCTAACTCAGTCCAGGCAGCCCGCCCTGCCCCAGCC CCAGTGCCAAGCCCAGCACCTCCTCAGCCGGTGCAGCCAGGGCCCCCTGGGGGCAGCAGGGCCACTCCTG GGCCAGGACGCTTTCCGGAGCAGAGCACAGAGGCTCCTCCAAGTGACCCTGGCTATCCAGGGGCTGTCGC CCCAGCCCGAGAGGAGAGGACAGGACCTGCGGGGGGCTTCCAGGCAGCGCCGCACACTGCAGCCCCCTAT TCCCAGGCAGCCCCTGCTCGCCAGCCACCACCTGCGGAGGAGGAGGAGGAAGAAGCCAATAGTTATGACT CTGATGAAGCAACCACACTGGGTGCCCTGGAATTCAGCCTTCTCTATGACCAAGACAACAGCAACCTGCA GTGCACCATCATCAGGGCGAAGGGACTGAAGCCCATGGATTCCAATGGCTTGGCAGATCCCTATGTGAAG CTTCATCTGCTGCCTGGAGCCAGCAAGTCCAACAAGCTTCGTACAAAGACCCTGCGCAACACTCGGAACC CTGTGTGGAATGAGACACTGCAGTATCATGGCATTACAGAGGAGGACATGCAGAGGAAGACACTAAGGAT CTCCGTGTGTGACGAGGACAAGTTTGGCCACAACGAGTTCATTGGTGAGACCAGGTTCTCGCTCAAGAAG CTGAAGGCTAACCAGAGGAAAAACTTCAACATCTGCCTGGAGCGGGTGATCCCGATGAAGAGAGCAGGGA CCACCGGGTCGGCCCGTGGCATGGCTCTCTATGAGGAGGAGCAGGTAGAGCGGATCGGCGATATAGAGGA ACGGGGCAAGATCCTGGTGTCCCTCATGTACAGCACGCAGCAGGGCGGCCTCATTGTGGGAATCATCCGC TGTGTGCACCTGGCCGCCATGGATGCCAACGGCTACTCAGACCCCTTTGTCAAGCTCTGGCTGAAACCGG ACATGGGGAAGAAAGCCAAGCACAAGACTCAGATTAAAAAGAAGACCCTGAATCCCGAGTTTAACGAGGA GTTCTTTTATGATATCAAACACAGCGACCTGGCTAAAAAGTCCCTGGATATCTCGGTGTGGGACTACGAC ATTGGCAAGTCTAATGATTACATCGGAGGCTGCCAGCTGGGGATCTCGGCCAAAGGCGAGCGCTTGAAAC ATTGGTATGAGTGTTTGAAGAACAAAGACAAGAAGATTGAGCGCTGGCACCAACTGCAGAACGAGAACCA CGTGTCCAGTGAT AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC TGGATTACAAGGATGACGACGATAAGGTTTAA This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 2 / 5 Rph3a (NM_011286) Mouse Tagged ORF Clone – MR210001 Protein Sequence: >MR210001 protein sequence Red=Cloning site Green=Tags(s) MTDTVVNRWMYPGDGPLQSNDKEQLQAGWSVHPGAQTDRQRKQEELTDEEKEIINRVIARAEKMEAMEQE RIGRLVDRLETMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKKNVCTKCGVETSNNRPHPVWLCKIC LEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQPAGEPATQEQPTPESRHPARAPARGDMEDRRPPG QKPGPDLTSAPGRGSHGPPTRRASEARMSTAARDSEGWDHAHGGGTGDTSRSPAGLRRANSVQAARPAPA PVPSPAPPQPVQPGPPGGSRATPGPGRFPEQSTEAPPSDPGYPGAVAPAREERTGPAGGFQAAPHTAAPY SQAAPARQPPPAEEEEEEANSYDSDEATTLGALEFSLLYDQDNSNLQCTIIRAKGLKPMDSNGLADPYVK LHLLPGASKSNKLRTKTLRNTRNPVWNETLQYHGITEEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKK LKANQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERIGDIEERGKILVSLMYSTQQGGLIVGIIR CVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYD IGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNENHVSSD SGPTRTRPLEQKLISEEDLAANDILDYKDDDDKV Restriction Sites: SgfI-RsrII Cloning Scheme: This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 3 / 5 Rph3a (NM_011286) Mouse Tagged ORF Clone – MR210001 Plasmid Map: ACCN: NM_011286 ORF Size: 2046 bp OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. RefSeq: NM_011286.3 RefSeq Size: 4163 bp RefSeq ORF: 2046 bp Locus ID: 19894 UniProt ID: P47708 MW: 75.5 kDa This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 4 / 5 Rph3a (NM_011286) Mouse Tagged ORF Clone – MR210001 Gene Summary: Plays an essential role in docking and fusion steps of regulated exocytosis (By similarity). At the presynaptic level, RPH3A is recruited by RAB3A to the synaptic vesicle membrane in a GTP-dependent manner where it modulates synaptic vesicle trafficking and calcium-triggered neurotransmitter release (By similarity). In the post-synaptic compartment, forms a ternary complex with GRIN2A and DLG4 and regulates NMDA receptor stability. Plays also a role in the exocytosis of arginine vasopressin hormone (By similarity).[UniProtKB/Swiss-Prot Function] This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 5 / 5.
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