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Selection of Relevant Dietary Indicators for Health

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Selection of Relevant Dietary Indicators for Health European Journal of Clinical Nutrition (2002) 56, Suppl 2, S8–S11 ß 2002 Nature Publishing Group All rights reserved 0954–3007/02 $25.00 www.nature.com/ejcn ORIGINAL COMMUNCIATION Selection of relevant dietary indicators for health L Steingrı´msdo´ttir1*, L Ovesen2, O Moreiras3 and S Jacob4 for the EFCOSUM Group 1Icelandic Nutrition Council, Reykjavı´k, Iceland; 2Danish Veterinary and Food Administration, Institute of Food Research and Nutrition, Søborg, Denmark; 3Departemento de Nutricio´n, Facultad de Farmacia, Universidad Compluyense de Madrid, Madrid, Spain; and 4Institute of Food Science, Laboratory for Human Nutrition, Swiss Federal Institute of Technology Zurich, Zurich, Switzerland Objective: To define a set of dietary components that are relevant determinants for health in Europe. The selected components are intended to serve as nutrition indicators for health in the European Health Monitoring Programme and, as such, must be limited in number, relevant to health in Europe and practical for all involved countries with respect to data gathering and comparability of data. Design: Major nutrition factors were determined by reviewing relevant epidemiological and clinical literature in nutrition and health as well as referring to reports from international expert groups, including the report from the project Nutrition and Diet for Healthy Lifestyles in Europe. The selection of factors was also based on the relative ease and cost involved for participating countries to obtain comparable and valid data. Results: The selected factors include foods or food groups as well as individual nutrients. Biomarkers are suggested for selected nutrients that pose the greatest difficulty in obtaining valid and comparable data from dietary studies. Conclusions: The following list of diet indicators for health monitoring in Europe was agreed upon by the EFCOSUM group in 2001, in order of priority: vegetables, fruit, bread, fish, saturated fatty acids as percentage of energy (%E), total fat as %E, and ethanol in grams per day. Biomarkers were suggested for the following nutrients: folate, vitamin D, iron, iodine and sodium. Energy has to be assessed in order to calculate %E from total fat and saturated fatty acids. Sponsorship: European Commission, DG SANCO F=3, Health Monitoring Programme. European Journal of Clinical Nutrition (2002) 56, Suppl 2, S8 – S11. DOI: 10.1038/sj/ejcn/1601423 Keywords: nutrition goals; dietary indicators; nutrition monitoring; food groups; nutrients; biomarkers Introduction where major nutritional factors relevant to health in Europe One of the aims of the European Food Consumption Survey are defined. These include a report on Health and Nutrition Method (EFCOSUM) is to define a set of dietary components prepared by the French Presidency of the European Union that are relevant determinants of health in Europe. These (French Presidency, 2000), which refers to the report from dietary components are intended to serve as nutrition indi- the project Nutrition and Diet for Healthy Lifestyles in cators in the European Health Monitoring Programme and, Europe (Eurodiet Reports and Proceedings, 2001), and as such, should be limited in number, relevant to health and reports from the World Health Organization, Regional practical for all involved countries with respect to data Office for Europe (Development of the First Food and Nutri- gathering and comparability of data. tion Action Plan for the European Region, 2000; Health 21, Epidemiological and clinical research in the field of nutri- 2000). Other nutrition factors are still controversial or need tion has identified several important dietary factors relevant further study to be generally accepted as major determinants to the development of chronic diseases. For many major for health or disease aetiology. This paper gives some of the factors there is general consensus among scientists with background and rationale used by EFCOSUM participants for respect to their role in disease aetiology. This consensus is defining a limited number of nutrition indicators relevant to reflected in international reports and nutrition action plans, health in Europe. Diet and health *Correspondence: L Steingrı´msdo´ttir, Icelandic Nutrition Council, Baro´nsstı´gur 47, 101 Reykjavı´k, Iceland. Cardiovascular disease (CVD) is the main cause of death in E-mail: [email protected] Europe, accounting for 43% of all deaths. However, there is a Relevant dietary indicators L Steingr´ımsdo´ttir et al S9 striking difference between European countries, the highest (excluding potatoes) for the general Dutch population. They rates being observed in Eastern Europe and the lowest in included all analytical studies published up to early 1998. France and the Mediterranean countries (Rayner & Peterson, There were 269 analyses on the association between intake of 2000). It is estimated that more than a third of cardiovas- fruit and vegetables and cancer (195 case – control; 74 pro- cular deaths of people under the age of 65 is attributable to spective), and 14 analyses on CVD (three case – control; 11 diet (Ferro-Luzzi & James, 1997). The most important dietary prospective studies). The preventable proportion of cancers factors are those that affect serum cholesterol levels, espe- and CVDs was calculated using three scenarios — best guess, cially the LDL cholesterol fraction (Adult Treatment Panel II, and optimistic and conservative guess — each representing a National Cholesterol Education Program, 1994). Thus, it is different set of assumptions or interpretations of the scien- widely accepted that diets high in saturated and trans unsa- tific evidence. The estimations were that an increase in the turated fatty acids increase the risk of CVD (Krauss et al, consumption of fruit and vegetables of 150 g per day (bring- 1996). However, some controversy has arisen regarding the ing the Dutch average intake to 400 g per day) would reduce beneficial effect of low total fat=high-carbohydrate diets on cancer deaths on average by 19% (best guess), ranging from CVD (Connors & Connors, 1997; Katan et al, 1997). Critics 6% (conservative guess) to 28% (optimistic guess). For CVD point out that low-fat diets may elevate triglyceride levels the proportion of preventable deaths was estimated at 16%, and lower not only LDL cholesterol but also HDL cholesterol. ranging from 6 to 22%. Thus, diets including moderate total fat, but low saturated The prevalence of obesity and overweight is rapidly fat, may result in an equally beneficial serum lipid profile increasing among all age groups in Europe, for both children and CVD risk to low fat diets. Epidemiological studies show and adults alike. Consequently, diseases resulting from that high consumption of fruit and vegetables is associated excess body fat, not the least diabetes type 2, are expected with a lowered risk of CVD, including both coronary heart to follow this development and become an ever-increasing disease and stroke (Klerk et al, 1998). The Dash study demon- burden on society and health care (WHO, 1998). Diabetes strated that dietary intervention with a combination diet prevalence is already rising rapidly in Europe, and it is that was high in fruit and vegetables and low-fat dairy estimated that at least 80% of diabetes type 2 is due to products decreased blood pressure in moderately hyperten- obesity and overweight. Lack of physical activity in daily sive subjects (Appel et al, 1997). Also diets including a weekly life combined with energy-dense, high-fat diets contributes fish meal are associated with lower cardiovascular risk to increased weight gain and obesity in most societies (Bray (Marckmann & Grønbæk, 1999), while sodium-rich diets & Popkin, 1998; Stookey, 2001). can contribute to hypertension and stroke (Sacks et al, Osteoporosis and the associated bone fractures among 2001). Finally, alcohol consumption is of significance to post-menopausal women and older men are predicted to ischaemic heart disease (IHD) and all-cause mortality as become an increasing burden on society as a result of the epidemiological studies have demonstrated that light to increasing age of European populations. Physical activity moderate drinkers of alcohol are at lower risk for IHD than and sufficient calcium and vitamin D from childhood to abstainers or heavy drinkers (Corrao et al, 2000; Sasaki, old age are preventive factors against osteoporosis (European 2000). Commission, 1997). Cancer accounts for 29% of all deaths in men and 22% in While the relative importance of nutritional deficiency women in the EU (French Presidency, 2000), and it is diseases has diminished in European populations in recent estimated that between 30 and 40% of these can be attrib- decades, certain nutrient deficiencies are still of concern. uted to dietary factors (Doll & Peto, 1981). Excess energy and This includes iron deficiency, which is prevalent among alcohol intake are risk factors for cancers of the mouth, young children and women of childbearing age in most pharynx, larynx, oesophagus and liver, while high intake European countries (UNICEF=WHO, 1999). Iodine deficiency of fruit and vegetables is associated with reduced risk of is also a health problem in many European countries, invol- cancers of the mouth, pharynx, oesophagus, stomach and ving 16% of the European region (Delange et al, 1993), and lungs (WCRF=AICR, 1997). Fruit and vegetables are rich only a few countries in Europe are free of iodine deficiency. sources of phytochemicals, with possible effects on slowing Lack of both of these micronutrients
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