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University Research Programs University Programs Cardiff University School of Biosciences Cardiff, CF14 9HS United Kingdom Contact Person: Professor J.L. Harwood Contact Information: e-mail: [email protected]; phone: +44 29 2087 4108; fax: +44 29-2087 4116; website Research Topics: Metabolism and function of fatty acids and acyl lipids including; control mechanisms for lipid accumulation in oil crops; changes in plant lipid metabolism brought about by herbicides or stress, including the Greenhouse Effect; membrane lipids and temperature adaptation; respiratory disease and pulmonary surfactant; polyunsaturated fatty acids and inflammatory disease (endotoxic shock, arthritis, Alzheimer's). Ghent University Faculty of Medicine and Social Sciences; Division of Nutrition Ghent University Hospital Ghent, Belgium Contact Person: Dr. A. Christophe Contact Information: e-mail: [email protected]; phone: +32 9 240 2262; fax: +32 9 240 3897 Research Topics: Fatty acid and antioxidant status of different groups and influencing it by dietary intervention. Ghent University Food Technology and Engineering Gent 9000 Belgium Contact Person: Kon Dewettinck Contact Information: e-mail: [email protected]; phone: +32 9 2646163; fax: +32 9 2646218 Research topics: fat crystallization; bakery products; dairy (phospholipids); powders Institute of Biochemistry Graz, Styria A-8010 Austria Contact Person: Prof. Dr. Albin Hermetter Contact Information: e-mail: [email protected]; phone: +43 316 873 6457; fax: +43 316 873 6952; website: http://www.biochemistry.tugraz.at Research Topics: Lipid oxidation, antioxidants, oxidized phospholipids, signal transduction in vascular smooth muscle cells, atherosclerosis; Lipolytic enzymes, lipases, esterases, sphingomyelinases, functional proteomics of lipid modifying enzymes, protein chip technology, microarrays Fluorescence spectroscopy and microscopy, fluorescent lipids, fluorescent enzyme inhibitors, fluorescence labeling of proteins Fluorescence assays for lipid and protein oxidation, antioxidant screening, and lipolytic enzymes (activity, mol active enzyme) Greifswald University Institute of Chemistry & Biochemistry Department of Technical Chemistry & Biotechnology Greifswald 17487 Germany Contact Person: Dr. Uwe T. Bornscheuer Contact Information: e-mail: [email protected]; phone: +49 3834 86 4367; fax: +49 3834 86 4346; website: www.chemie.uni-greifswald.de/~biotech/ Research Topics: Biocatalysis using e.g.. lipases and phopholipase; screening, cloning expression of enzymes; optimization by rational protein design/directed evolution; application in biocatalytic reactions, e.g. synthesis of phospholipids, structured triglycerides. Iowa State University Department of Food Science and Human Nutrition Ames, Iowa 50011-1061 USA Contact Person: Brenda Emery Contact Information: e-mail: [email protected]; phone: +1 515 294 3011; fax: +1 515 294 8181; website: www.fcs.iastate.edu/fshn Research Topics: Grain Processing, Oil Chemistry and Processing, Protein Separation, Functionality and Application Iowa State University Grain Quality Laboratory Ames, Iowa 50011 USA Contact Person: Dr. Charles R. Hurburgh, Jr. Contact Information: e-mail: [email protected]; phone: +1 515 294 8629; fax: +1 515 294 6383; website: www.iowagrain.org; www.grainlab.org Research Topics: Near Infrared spectrosopy; Chemometrics and calibration of multivariate sensors; Quality management systems; Food security and traceability; Soybean quality improvement; See www.iowagrain.org for current openings. Kansas State University Division of Biology; Kansas Lipidomics Research Center; KSU Lipidomics/Lipid Signaling Group Manhattan, Kansas 66506 USA Contact Person: Dr. David Rintoul Contact Information: e-mail: [email protected]; phone: +1 785 532 0104; website: www.ksu.edu/biology; www.ksu.edu/lipid/lipidomics; www.ksu.edu/lipid/ Research Topics: Lipid metabolism in hibernating marmots; lipid metabolism in migratory birds Karolinska Institutet Medical Biochemistry and Biophysics Stockholm SE-17177 Sweden Contact Person: Mats Hamberg Contact Information: e-mail: [email protected]; phone: +46 8 52487640; website: www.mbb.ki.se/research/kemi_2/MH/mhintro1.htm Research Topics: Research carried out in our laboratory concerns various aspects of oxylipins, oxygenated fatty acid derivatives formed by mono- or dioxygenase-catalyzed oxygenation of fatty acids. Fatty acid hydroperoxides constitute an important group of oxylipins which are formed by action of lipoxygenases as well as recently discovered alpha-dioxygenases. Further metabolism of hydroperoxides results in the formation of biologically important compounds such as the leukotrienes in animals and jasmonates in plants. Our current work is focussed on studies of the biosynthesis and metabolism of oxylipins in higher plants as well on the development of new methods for synthesis and analysis of oxylipins. Recent publications: Hamberg, M., Sanz, A., Rodriguez, M.J., Calvo, A.P., and Castresana, C. (2003) Activation of the alpha-dioxygenase pathway during bacterial infection of tobacco leaves: Formation of oxylipins protecting against cell death. J. Biol. Chem. 278:51796-51805. Grechkin, A.N., Mukhtarova, L.S., and Hamberg, M. (2003) Detection of an enol intermediate in the hydroperoxide lyase chain cleavage reaction. FEBS Lett. 549:31-34. London Metropolitan University Institute of Brain Chemistry and Human Nutrition London N7 8DB United Kingdom Contact Person: Professor Michael A. Crawford Contact Information: e-mail: [email protected]; phone: +44 020 7753 3165; fax: +44 020 7753 3164; website: www.unl.ac.uk/ibchn Research Topics: Membrane Protein/lipid and lipid/ lipid domains and their influence on signaling and gene expression; Membrane lipid distortion in the aetiology of chronic diseases such as diabetes, sickle cell anemia etc.; The role of arachidonic acid deficiency in impaired vascular development and fragility, viz. the complications of prematurity and haemorrhagic stroke; Maternal nutrition, prenatal programming and pregnancy outcome. National University of Malaysia Department of Chemical Science & Food Technology Bangi, Selangor 43600 Malaysia Contact Person: Sri Nurestri Hj Abdul Malek, Assoc. Prof. Datin Dr. Contact Information: e-mail: [email protected]; phone: +6 03 8921 5446; fax: +6 03 8921 5410; website: http://pkukmweb.ukm.m/%7Ekimia Research Topics: Studies on plants that have potential medicinal properties; Investigations into the volatile constituents of plants and flowers that may be utilized in the flavor and fragrance industries; Investigations into certain biological activities of Melastoma malabathricum; Studies on Trema orientalis; Investigations into the components of several wild species of ginger; Isolation and synthesis of several derivatives of milletenone from Millettia hemsleyana. North Dakota State University Department of Cereal and Food Sciences Fargo, North Dakota 58105 USA Contact Person: Charlene Kuss Contact Information: e-mail: [email protected]; phone: +1 701 231 7712; fax: +1 701 231 6359; website: http://www.ndsu.nodak.edu/cereal-science/ Research Topics: Hard Red Spring Wheat - Dough Rheology and Baking; Durum Wheat - Pasta Processing; Carbohydrates; Proteins; Alternative Crops; Food Processing; Lipids Oklahoma State University Department of Biosystems and Agricultural Engineering/Food Science Stillwater, Oklahoma 74078 USA Contact Person: Dr. Nurhan Dunford Contact Information:e-mail: [email protected]; phone: +1 405 744 7062; fax: +1 405 744 6313; website: Biosystems Engineering Department: http://biosystems.okstate.edu/faculty/dunford_index.html Bioenergy Center: http://bioenergycenter.okstate.edu/faculty/Dunford Robert M. Kerr Food and Agricultural Products Center: http://www.fapc.okstate.edu/services/oil.html Research Topics: Oil and Oilseed processing, functional foods and nutraceuticals, specialty oils, supercritical fluid technology, biocatalysis, green processing, and value-added bioprocessing, waste utilization. Oregon State University Linus Pauling Institute Corvallis, Oregon, 97331 USA Contact Name: Balz Frei, Ph.D. Contact Information: e-mail: [email protected]; phone: +1 541 737 5075; fax: +1 541 737 5077; website: http://lpi.oregonstate.edu Research Topics: Our mission is to determine the function and role of micronutrients (vitamins, minerals, and others) and phytochemicals (chemicals from plants) in promoting optimum health and preventing and treating disease; to determine the role of oxidative and nitrative stress and antioxidants in human health and disease; and to advance knowledge in areas that were of interest to Linus Pauling through research and educational activities. The Institute functions from the basic premise that an optimum diet is the key to optimum health. Major areas of research in the Institute encompass heart disease, cancer, aging, neurodegenerative diseases and disease caused by exposure to toxins. Specific laboratories address antioxidants and vascular biology; vitamin E metabolism and biological activity; colon cancer and cancer chemoprevention by phytochemicals; the role of nitric oxide and oxidative tress in neurodegenerative diseases, such as ALS (Lou Gehrig's disease); and the role of oxidative stress and mitochondrial dysfunction in the aging process. The Linus Pauling Institute was established at Oregon State University in August 1996 under an agreement reached between OSU and its antecedent organization, the Linus Pauling Institute of Science and Medicine (located
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