Local Anaesthesia for Your Eye Operation
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Ketamine for Paediatric Sedation/Analgesia in the Emergency Department
275 Emerg Med J: first published as 10.1136/emj.2003.005769 on 22 April 2004. Downloaded from CLINICAL TOPIC REVIEW Emerg Med J: first published as 10.1136/emj.2003.005769 on 22 April 2004. Downloaded from Ketamine for paediatric sedation/analgesia in the emergency department M C Howes ............................................................................................................................... Emerg Med J 2004;21:275–280. doi: 10.1136/emj.2003.005769 This review investigates the use of ketamine for paediatric pain or other noxious stimuli, with relative preservation of respiratory and cardiovascular sedation and analgesia in the emergency department functions despite profound amnesia and analge- ........................................................................... sia,10 30–32 described as ‘‘cataleptic.’’10 This trance- like state of sensory isolation provides a unique combination of amnesia, sedation, and analge- he injured child presents a challenge to sia.7103031 The eyes often remain open, though emergency department (ED) practitioners. nystagmus is commonly seen. Heart rate and The pain and distress can be upsetting for T blood pressure remain stable, and are often staff as well as parents. The child’s distress can stimulated, possibly through sympathomimetic be compounded by the fear of a painful actions.30 31 33 Functional residual capacity and procedure to follow, previous conditioning from tidal volume are preserved, with bronchial unexpected ‘‘jabs’’ when receiving immunisa- smooth muscle relaxation34–37 and maintenance tions, or previous visits to an ED.1 of airway patency and respiration.10 30 31 38 As doctors we strive to relieve pain and However, despite the enthusiasm of many suffering, and swear to do no harm. Forced authors and practitioners, ketamine may not be restraint, still performed in some departments in the ideal agent. -
A Comparative Study of Anaesthetic Agents on High Voltage Activated Calcium
bioRxiv preprint doi: https://doi.org/10.1101/2020.12.17.423182; this version posted December 18, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license. A COMPARATIVE STUDY OF ANAESTHETIC AGENTS ON HIGH VOLTAGE ACTIVATED CALCIUM CHANNEL CURRENTS IN IDENTIFIED MOLLUSCAN NEURONS Terrence J. Morris1, Philip M. Hopkins2,3 and William Winlow4,5 1Department Science and Technology - Biology, Douglas College, 700 Ryal Avenue, New Westminster, British Columbia, Canada; 2 Leeds Institute of Medical Research at St James’s, School of Medicine, University of Leeds, Leeds, United Kingdom; 3Malignant Hyperthermia Investigation Unit, Leeds Institute of Molecular Medicine, St. James’s University Hospital, Leeds, LS9 7TF, United Kingdom; 4 Department of Biology, University of Naples Federico II, Via Cintia 26, 80126, Naples, Italy; 5Institute of Ageing and Chronic Diseases, University of Liverpool, Liverpool, United Kingdom. Corresponding author: William Winlow Key Words: General anaesthetic, calcium channels, Lymnaea, light yellow cells SUMMARY 1. Using the two electrode voltage clamp configuration, a high voltage activated whole-cell Ca2+ channel current (IBa) was recorded from a cluster of neurosecretory ‘Light Yellow’ Cells (LYC) in the right parietal ganglion of the pond snail Lymnaea stagnalis. 2. Recordings of IBa from LYCs show a reversible concentration-dependent depression of current amplitude in the presence of the volatile anaesthetics halothane, isoflurane and sevoflurane, or the non-volatile anaesthetic pentobarbitone at clinical concentrations. 3. In the presence of the anaesthetics investigated, IBa measured at the end of the depolarizing test pulse showed proportionally greater depression than that at measured peak amplitude, as well as significant decrease in the rate of activation or increase in inactivation or both. -
Anesthesia for Eye Surgery
Anesthesia for Eye Surgery Having a surgery can be stressful. We would like to provide you the following information to help you prepare for your eye surgery. Eye surgeries are typically done under topical or local anesthesia with or without mild sedation. Topical Anesthesia This is administered via special eye drops by a preoperative nurse. Local Anesthesia This is administered via injection by an ophthalmologist. Your ophthalmologist will inject local anesthesia to the eye that is to undergo the operation. During the injection, you will be lightly sedated. In the operating room During the procedure it is very important that you remain still. This is a very delicate surgery; any abrupt movement can hinder a surgeon’s performance. If you have any concerns during the surgery, such as pain, urge to cough or itching, please let us know immediately. Typically, patients are not heavily sedated for this type of procedure. Therefore, it is normal for patients to feel pressure around their eyes, but not pain. In order to maintain surgical sterility, your face and body will be covered with a sterile drape. You will be given supplemental oxygen to breathe. An anesthesia clinician will continue to monitor your vital signs for the duration of the procedure. The length of the procedure usually ranges from 10 minutes to 30 minutes. In the recovery room After surgery, you will be brought to the recovery room. A recovery room nurse will continue to monitor your vital signs for the next 20 to 30 minutes. It is important that you do not drive or operate any machinery for the next 24 hours. -
Table of Contents
Leadership Development Program Project Abstracts Table of Contents LDP XXII, CLASS OF 2020 GRADUATES Name/Society/Project Page John J. Chen, MD, PhD 1 North American Neuro-Ophthalmology Society Project: The Neuro-Ophthalmology career path: misconceptions and barriers to recruitment Jeremy D. Clark, MD 2 Kentucky Academy of Eye Physicians and Surgeons Project: The Web of Innovation: Silent Auction Benefitting Political Action funds in Kentucky Gennifer J. Greebel, MD 3 New York State Ophthalmological Society Project: Inspiring Professional Aspirations in Adolescents with Low Vision Mark A. Greiner, MD 4 Eye Bank Association of America Project: Revisiting Eye Banking Medical Standards To Accommodate Emerging Technologies Jennifer F. Jordan, MD 5 North Carolina Society of Eye Physicians and Surgeons Project: Advocacy Exposure for North Carolina Ophthalmologists in Training Kapil G. Kapoor, MD 6 Virginia Society of Eye Physicians and Surgeons Project: Unwrapping Virginia Bill 506B Erin Lichtenstein, MD 7 Maine Society of Eye Physicians and Surgeons Project: Bringing Ophthalmology Residents to Maine Jennifer L. Lindsey, MD 8 Association of Veterans Affairs Ophthalmologists Project: Illuminating the Path to Advocacy for Veterans Affairs Ophthalmologists Donald A. Morris, DO 9 American Osteopathic College of Ophthalmology Project: Single Accreditation of Ophthalmology residencies is here. What is the next step? Lisa Nijm, MD, JD 10 Women in Ophthalmology Project: Implementing a Clinical Trials Training Program to Increase Diversity of Primary Investigators Involved in Ophthalmic Research LDP XXII, CLASS OF 2020 GRADUATES (cont’d) Name/Society/Project Page Roma P. Patel, MD, MBA 11 California Academy of Eye Physicians and Surgeons Project: Increasing Membership Value to our CAEPS Members Jelena Potic, MD, PhD 12 European Society of Ophthalmology Project: Harmonization of Surgical Skills Standards for Young Ophthalmologists across Europe Pradeep Y. -
Laser Vision Correction Surgery
Patient Information Laser Vision Correction 1 Contents What is Laser Vision Correction? 3 What are the benefits? 3 Who is suitable for laser vision correction? 4 What are the alternatives? 5 Vision correction surgery alternatives 5 Alternative laser procedures 5 Continuing in glasses or contact lenses 5 How is Laser Vision Correction performed? 6 LASIK 6 Surface laser treatments 6 SMILE 6 What are the risks? 7 Loss of vision 7 Additional surgery 7 Risks of contact lens wear 7 What are the side effects? 8 Vision 8 Eye comfort 8 Eye Appearance 8 Will laser vision correction affect my future eye health care? 8 How can I reduce the risk of problems? 9 How much does laser vision correction cost? 9 2 What is Laser Vision Correction? Modern surgical lasers are able to alter the curvature and focusing power of the front surface of the eye (the cornea) very accurately to correct short sight (myopia), long sight (hyperopia), and astigmatism. Three types of procedure are commonly used in If you are suitable for laser vision correction, your the UK: LASIK, surface laser treatments (PRK, surgeon will discuss which type of procedure is the LASEK, TransPRK) and SMILE. Risks and benefits are best option for you. similar, and all these procedures normally produce very good results in the right patients. Differences between these laser vision correction procedures are explained below. What are the benefits? For most patients, vision after laser correction is similar to vision in contact lenses before surgery, without the potential discomfort and limitations on activity. Glasses may still be required for some activities after Short sight and astigmatism normally stabilize in treatment, particularly for reading in older patients. -
New Horizons Forum
Speeding the development of new therapies and diagnostics for glaucoma patients New Horizons Forum Friday, February 9, 2018 Palace Hotel, San Francisco, CA © Aerie Pharmaceuticals, Inc. Irvine, CA 92614 Follow the meeting on Twitter: #Glaucoma360 MLR-0002 Glaucoma Research Foundation thanks the following sponsors WELCOME for their generous support of Glaucoma 360 PLATINUM It is our sincere pleasure to welcome you to the 7th Annual Glaucoma 360: New Horizons Forum, hosted by Glaucoma Research Foundation. This important meeting provides a unique opportunity to bring together leaders in medicine, science, industry, venture capital, and the FDA to discuss emerging ideas in glaucoma and encourage collaboration to accelerate their development for clinical use. Since its establishment in 2012, this annual forum continues to grow and provide the ultimate opportunity to highlight important advances and facilitate networking between these essential groups. As a result, there are now more effective therapies and diagnostic tools in clinical practice today to help doctors manage the disease more effectively. But, unmet medical needs remain in glaucoma. Glaucoma Research Foundation is resolute in its mission to preserve vision and continue its role as a catalyst in the advancement of research towards new treatments and a cure. SILVER Glaucoma 360 would not be possible without the generous and selfless contributions of so many including: members of our Advisory Board, Program and Steering Committees who have volunteered their time to build an outstanding agenda; our dedicated sponsors who have helped to underwrite this event; our speakers, presenters, and panelists who are ready to share their expertise and unique perspectives; our attendees; the support of our Board of Directors and staff at Glaucoma Research Foundation; and the hard working team at The Palace Hotel. -
Dionaea Muscipula)
bioRxiv preprint doi: https://doi.org/10.1101/645150; this version posted May 22, 2019. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license. 1 RESEARCH PAPER 2 Anaesthesia with diethyl ether impairs jasmonate signalling in the 3 carnivorous plant Venus flytrap (Dionaea muscipula). 4 Andrej Pavlovič1*, Michaela Libiaková2, Boris Bokor2,3, Jana Jakšová1, Ivan Petřík4, Ondřej 5 Novák4, František Baluška5 6 1 Department of Biophysics, Centre of the Region Haná for Biotechnological and Agricultural 7 Research, Faculty of Science, Palacký University, Šlechtitelů 27, CZ-783 71, Olomouc, Czech 8 Republic 9 2 Department of Plant Physiology, Faculty of Natural Sciences, Comenius University in 10 Bratislava, Ilkovičova 6, Mlynská dolina B2, SK-842 15, Bratislava, Slovakia 11 3 Comenius University Science Park, Comenius University in Bratislava, Ilkovičova 8, SK-841 12 04, Bratislava, Slovakia 13 4 Laboratory of Growth Regulators, Centre of the Region Haná for Biotechnological and 14 Agricultural Research, Institute of Experimental Botany CAS and Faculty of Science, Palacký 15 University, Šlechtitelů 27, CZ-783 71, Olomouc, Czech Republic 16 5IZMB, University of Bonn, Kirschallee 1, 53115 Bonn, Germany 17 *- author for correspondence: [email protected], +420 585 634 831 18 Running title: Anaesthetic impairs jasmonate signalling in carnivorous plant 19 Highlight: Carnivorous plant Venus flytrap (Dionaea muscipula) is unresponsive to insect 20 prey or herbivore attack due to impaired electrical and jasmonate signalling under general 21 anaesthesia induced by diethyl ether. -
Nerve Blocks for Surgery on the Shoulder, Arm Or Hand
The Association of Regional The Royal College of Anaesthetists of Great Anaesthesia – Anaesthetists Britain and Ireland United Kingdom Nerve blocks for surgery on the shoulder, arm or hand Information for patients and families www.rcoa.ac.uk/patientinfo First edition 2015 This leaflet is for anyone who is thinking about having a nerve block for an operation on the shoulder, arm or hand. It will be of particular interest to people who would prefer not to have a general anaesthetic. The leaflet has been written with the help of patients who have had a nerve block for their operation. You can find more information leaflets on the website www.rcoa.ac.uk/patientinfo. The leaflets may also be available from the anaesthetic department or pre-assessment clinic in your hospital. The website includes the following: ■ Anaesthesia explained (a more detailed booklet). ■ You and your anaesthetic (a shorter summary). ■ Your spinal anaesthetic. ■ Anaesthetic choices for hip or knee replacement. ■ Epidural pain relief after surgery. ■ Local anaesthesia for your eye operation. ■ Your child’s general anaesthetic. ■ Your anaesthetic for major surgery with planned high dependency care afterwards. ■ Your anaesthetic for a broken hip. Risks associated with your anaesthetic This is a collection of 14 articles about specific risks associated with having an anaesthetic or an anaesthetic procedure. It supplements the patient information leaflets listed above and is available on the website: www.rcoa.ac.uk/patients-and-relatives/risks. Throughout this leaflet and others in the series, we have used this symbol to highlight key facts. 2 NERVE BLOCKS FOR SURGERY ON THE SHOULDER, ARM OR HAND Brachial plexus block? The brachial plexus is the group of nerves that lies between your neck and your armpit. -
Local Anaesthetic Informed Consent
Local anaesthetic Informed consent: patient information This information sheet answers frequently asked questions about having local anaesthetic. It has been developed to be used in discussion with your doctor or healthcare professional. 1. What is local anaesthetic and how will 3. What are my specific risks? it help me? There may also be risks specific to your A local anaesthetic is used to numb a small individual condition and circumstances. Your part of your body and stop you feeling pain. doctor/healthcare professional will discuss You will be awake and aware of what is these with you. Ensure they are written on the © The State of Queensland (Queensland Health) 2017 Health) (Queensland Queensland of State The © To request permission email: [email protected] email: permission request To happening. Local anaesthetic is used when consent form before you sign it. nerves can be easily reached by drops, sprays, 4. What are the risks of not having this ointments or injections. anaesthetic? Except as permitted under the Copyright Act 1968, no part of this work may be may work this no part of 1968, Act the Copyright under permitted as Except Local anaesthetic generally has less side-effects reproduced communicated or adapted without permission from Queensland Health Queensland from permission without or adapted communicated reproduced and risks than a general anaesthetic (which is There may be consequences if you choose not to also generally a safe procedure if required). have the proposed anaesthetic. Please discuss these with your doctor/healthcare professional. For some procedures or operations, sedation is given with local anaesthetic. -
Root Eye Dictionary a "Layman's Explanation" of the Eye and Common Eye Problems
Welcome! This is the free PDF version of this book. Feel free to share and e-mail it to your friends. If you find this book useful, please support this project by buying the printed version at Amazon.com. Here is the link: http://www.rooteyedictionary.com/printversion Timothy Root, M.D. Root Eye Dictionary A "Layman's Explanation" of the eye and common eye problems Written and Illustrated by Timothy Root, M.D. www.RootEyeDictionary.com 1 Contents: Introduction The Dictionary, A-Z Extra Stuff - Abbreviations - Other Books by Dr. Root 2 Intro 3 INTRODUCTION Greetings and welcome to the Root Eye Dictionary. Inside these pages you will find an alphabetical listing of common eye diseases and visual problems I treat on a day-to-day basis. Ophthalmology is a field riddled with confusing concepts and nomenclature, so I figured a layman's dictionary might help you "decode" the medical jargon. Hopefully, this explanatory approach helps remove some of the mystery behind eye disease. With this book, you should be able to: 1. Look up any eye "diagnosis" you or your family has been given 2. Know why you are getting eye "tests" 3. Look up the ingredients of your eye drops. As you read any particular topic, you will see that some words are underlined. An underlined word means that I've written another entry for that particular topic. You can flip to that section if you'd like further explanation, though I've attempted to make each entry understandable on its own merit. I'm hoping this approach allows you to learn more about the eye without getting bogged down with minutia .. -
Cme Reviewarticle
Volume 58, Number 2 OBSTETRICAL AND GYNECOLOGICAL SURVEY Copyright © 2003 by Lippincott Williams & Wilkins, Inc. CME REVIEWARTICLE 5 CHIEF EDITOR’S NOTE: This article is part of a series of continuing education activities in this Journal through which a total of 36 AMA/PRA category 1 credit hours can be earned in 2003. Instructions for how CME credits can be earned appear on the last page of the Table of Contents. Ocular Changes in Pregnancy Robert B. Dinn, BS,* Alon Harris, MSc, PhD† and Peter S. Marcus, MD‡ *Fourth Year Medical Student, Indiana University School of Medicine; †Professor, Glaucoma Research and Diagnostic Center, Departments of Ophthalmology and Physiology, Indiana University School of Medicine; and ‡Assistant Clinical Professor, Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, Indiana Visual changes in pregnancy are common, and many are specifically associated with the preg- nancy itself. Serous retinal detachments and blindness occur more frequently during preeclampsia and often subside postpartum. Pregnant women are at increased risk for the progression of preexisting proliferative diabetic retinopathy, and diabetic women should see an ophthalmologist before pregnancy or early in the first trimester. The results of refractive eye surgery before, during, or immediately after pregnancy are unpredictable, and refractive surgery should be postponed until there is a stable postpartum refraction. A decreased tolerance to contact lenses also is common during pregnancy; therefore, it is advisable to fit contact lenses postpartum. Furthermore, preg- nancy is associated with a decreased intraocular pressure in healthy eyes, and the effects of glaucoma medications on the fetus and breast-fed infant are largely unknown. -
Anaesthesia for Cancer Patients Mujeebullah Rauf Arain and Donal J
Anaesthesia for cancer patients Mujeebullah Rauf Arain and Donal J. Buggy Purpose of review Introduction Cancer is beginning to outpace cardiovascular disease as Cancer is the second leading cause of death in the devel- the primary cause of death in the developed world. A oped world, accounting in 2004 for over half a million majority of cancer patients will require anaesthesia either for deaths. Cancers at four organ sites – lung/bronchus, colo- primary debulking tumour removal or to treat an adverse rectal, breast and prostate – accounted for 56% of all consequence of the malignant process or its treatment. cancer cases and 53% of all cancer deaths [1]. Approxim- Therefore we outline here the pathophysiology of cancer, ately half of patients diagnosed with cancer will develop generalized metastatic disease and systemic chemotherapy metastatic disease. Over 70% of all cancer patients develop and radiotherapy on major organ systems. The anaesthetic symptoms from either their primary or metastatic disease considerations for optimum perioperative management of [2]. The overall metastatic burden and the number and cancer patients are discussed, and the possibility of location of the sites involved by disease influence prog- anaesthetic technique at primary cancer surgery affecting nosis. There is an increasing surgical intervention rate long-term cancer outcome is mentioned. in cancer patients, both for primary tumour excision Recent findings and emergency intervention for intercurrent illness. Cancer and its therapy can adversely affect every major Coupled with the increased use of chemotherapeutic organ system with profound implications for perioperative agents over the past decade, cancer patients requiring management. Retrospective analysis suggests an surgery present particular challenges for the anaesthe- association between regional anaesthetic techniques at tist [2].