DOCSLIB.ORG

Therapeutic Drug Class

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text

Load more

BUREAU FOR MEDICAL SERVICES WEST VIRGINIA MEDICAID EFFECTIVE PREFERRED DRUG LIST WITH PRIOR AUTHORIZATION CRITERIA 10/1/12 This is not an all-inclusive list of available covered drugs and includes only managed categories. Refer to cover page for complete list of rules governing this PDL. Version 2012.7b Prior authorization for a non-preferred agent in any category will be given only if there has been a trial of the preferred brand/generic equivalent or preferred formulation of the active ingredient, at a therapeutic dose, that resulted in a partial response with a documented intolerance. Prior authorization of a non-preferred isomer, pro-drug, or metabolite will be considered with a trial of a preferred parent drug of the same chemical entity, at a therapeutic dose, that resulted in a partial response with documented intolerance or a previous trial and therapy failure, at a therapeutic dose, with a preferred drug of a different chemical entity indicated to treat the submitted diagnosis. (The required trial may be overridden when documented evidence is provided that the use of these preferred agent(s) would be medically contraindicated.) Unless otherwise specified, the listing of a particular brand or generic name includes all legend forms of that drug. OTC drugs are not covered unless specified. PA criteria for non-preferred agents apply in addition to general Drug Utilization Review policy that is in effect for the entire pharmacy program, including, but not limited to, appropriate dosing, duplication of therapy, etc. The use of pharmaceutical samples will not be considered when evaluating the members’ medical condition or prior prescription history for drugs that require prior authorization. Acronyms CL - Requires clinical PA. For detailed clinical criteria, please refer to: http://www.dhhr.wv.gov/bms/Pharmacy/Pages/PriorAuthorizationCriteria.aspx NR - New drug has not been reviewed by P & T Committee AP - Non-preferred and selected preferred drugs, where indicated, are subject to auto-PA criteria. See PA criteria column. 1 BUREAU FOR MEDICAL SERVICES WEST VIRGINIA MEDICAID EFFECTIVE PREFERRED DRUG LIST WITH PRIOR AUTHORIZATION CRITERIA 10/1/12 This is not an all-inclusive list of available covered drugs and includes only managed categories. Refer to cover page for complete list of rules governing this PDL. Version 2012.7b THERAPEUTIC PREFERRED AGENTS NON-PREFERRED AGENTS PA CRITERIA DRUG CLASS ACNE AGENTS (Topical)AP ANTI-INFECTIVE AZELEX (azelaic acid) ACZONE (dapsone) Thirty (30) day trials each of one clindamycin gel, lotion, medicated swab, AKNE-MYCIN (erythromycin) preferred retinoid and two unique solution CLEOCIN-T (clindamycin) chemical entities in two other erythromycin gel, solution CLINDACIN PAC (clindamycin) subclasses, including the generic sulfacetamide suspension CLINDAGEL (clindamycin) version of a requested non- clindamycin foam preferred product, are required erythromycin medicated swab before a non-preferred agent will be EVOCLIN (clindamycin) authorized unless one of the KLARON (sodium sulfacetamide) exceptions on the PA form is OVACE/PLUS (sulfacetamide) present. (In cases of pregnancy, a sulfacetamide cleanser trial of retinoids will not be required.) RETINOIDS RETIN A MICRO (tretinoin) adapalene PA required after 17 years of age TAZORAC (tazarotene) ATRALIN (tretinoin) for tretinoin products. AVITA (tretinoin) DIFFERIN (adapalene) RETIN-A (tretinoin) tretinoin cream, gel KERATOLYTICS benzoyl peroxide cleanser OTC, 10% cream BENZEFOAM (benzoyl peroxide) Acne kits are non-preferred. OTC, gel Rx & OTC, lotion OTC, 5% & BENZEFOAM ULTRA (benzoyl peroxide) 10% wash OTC benzoyl peroxide cloths, medicated pads TL 4.25% BPO MX (benzoyl peroxide) benzoyl peroxide/aloe OTC benzoyl peroxide/urea BPO (benzoyl peroxide) DELOS (benzoyl peroxide) DESQUAM-X (benzoyl peroxide) LAVOCLEN (benzoyl peroxide) PACNEX/HP/LP (benzoyl peroxide) PANOXYL-4, -8 OTC (benzoyl peroxide) PERSA-GEL OTC (benzoyl peroxide) SASTID (sulfur) SE-BPO (benzoyl peroxide) SULPHO-LAC (sulfur) COMBINATION AGENTS 2 BUREAU FOR MEDICAL SERVICES WEST VIRGINIA MEDICAID EFFECTIVE PREFERRED DRUG LIST WITH PRIOR AUTHORIZATION CRITERIA 10/1/12 This is not an all-inclusive list of available covered drugs and includes only managed categories. Refer to cover page for complete list of rules governing this PDL. Version 2012.7b THERAPEUTIC PREFERRED AGENTS NON-PREFERRED AGENTS PA CRITERIA DRUG CLASS erythromycin/benzoyl peroxide 10-1 (sulfacetamide/sulfur) Thirty (30) day trials each of one sulfacetamide solution ACANYA (clindamycin phosphate/benzoyl preferred retinoid and two unique sulfacetamide/sulfur wash/cleanser peroxide) chemical entities in two other subclasses, including the generic AVAR/-E/LS (sulfur/sulfacetamide) version of a requested non- BENZACLIN GEL (benzoyl peroxide/ preferred product, are required clindamycin) before a non-preferred agent will be BENZAMYCIN PAK (benzoyl peroxide/ authorized unless one of the erythromycin) exceptions on the PA form is benzoyl peroxide/clindamycin gel present. (In cases of pregnancy, a benzoyl peroxide/urea trial of retinoids will not be required.) CERISA (sulfacetamide sodium/sulfur) CLARIFOAM EF (sulfacetamide/sulfur) In addition, thirty (30) day trials of CLENIA (sulfacetamide sodium/sulfur) combinations of the corresponding DUAC (benzoyl peroxide/ erythromycin) preferred single agents available EPIDUO (adapalene/benzoyl peroxide) are required before non-preferred GARIMIDE (sulfacetamide/sulfur) combination agents will be INOVA 4/1, 5/2 (benzoyl peroxide/salicylic authorized. acid) NUOX (benzoyl peroxide/sulfur) PRASCION (sulfacetamide sodium/sulfur) SE 10-5 SS (sulfacetamide/sulfur) SSS 10-4 (sulfacetamide /sulfur) sulfacetamide sodium/sulfur cloths, lotion, pads, suspension sulfacetamide sodium/sulfur/ urea SUMADAN (sulfacetamide/sulfur) SUMAXIN/TS (sulfacetamide sodium/sulfur) VELTIN (clindamycin/tretinoin) ZIANA (clindamycin/tretinoin) ALZHEIMER’S AGENTSAP CHOLINESTERASE INHIBITORS donepezil ARICEPT (donepezil) A thirty (30) day trial of a preferred ARICEPT 23mg (donepezil) agent is required before a non- ARICEPT ODT(donepezil) preferred agent in this class will be COGNEX (tacrine) authorized unless one of the donepezil ODT exceptions on the PA form is EXELON CAPSULE (rivastigmine) present. EXELON PATCH (rivastigmine) galantamine Aricept 23mg tablets will be 3 BUREAU FOR MEDICAL SERVICES WEST VIRGINIA MEDICAID EFFECTIVE PREFERRED DRUG LIST WITH PRIOR AUTHORIZATION CRITERIA 10/1/12 This is not an all-inclusive list of available covered drugs and includes only managed categories. Refer to cover page for complete list of rules governing this PDL. Version 2012.7b THERAPEUTIC PREFERRED AGENTS NON-PREFERRED AGENTS PA CRITERIA DRUG CLASS galantamine ER approved when there is a diagnosis RAZADYNE (galantamine) of moderate-to-severe Alzheimer’s RAZADYNE ER (galantamine) Disease, a trial of donepezil 10mg rivastigmine daily for at least three (3) months, and donepezil 20mg daily for an additional one (1) month. Aricept and donepezil ODT will be approved only when the oral dosage form is not appropriate for the patient. Members currently utilizing Exelon patches as of 1/1/2012 may continue. NMDA RECEPTOR ANTAGONIST NAMENDA (memantine) ANALGESICS, NARCOTIC - SHORT ACTING (Non-parenteral)AP APAP/codeine ABSTRAL (fentanyl) Six (6) day trials of at least four (4) ASA/codeine ACTIQ (fentanyl) chemically distinct preferred agents codeine butalbital/APAP/caffeine/codeine (based on narcotic ingredient only), dihydrocodeine/ APAP/caffeine butalbital/ASA/caffeine/codeine including the generic formulation of hydrocodone/APAP butorphanol a requested non-preferred product, hydrocodone/ibuprofen COMBUNOX (oxycodone/ibuprofen) are required before a non-preferred hydromorphone tablets DEMEROL (meperidine) agent will be authorized unless one levorphanol DILAUDID (hydromorphone) of the exceptions on the PA form is morphine fentanyl present. oxycodone FENTORA (fentanyl) oxycodone/APAP FIORICET W/ CODEINE Fentanyl lozenges and Onsolis will oxycodone/ASA (butalbital/APAP/caffeine/codeine) only be approved for a diagnosis of pentazocine/APAP FIORINAL W/ CODEINE cancer and as an adjunct to a long- pentazocine/naloxone (butalbital/ASA/caffeine/codeine) acting agent. Neither will be ROXICET (oxycodone/acetaminophen) hydromorphone liquid approved for monotherapy. tramadol LAZANDA (fentanyl) tramadol/APAP LORCET (hydrocodone/APAP) Limits: Unless the patient has LORTAB (hydrocodone/APAP) escalating cancer pain or another MAGNACET (oxycodone/APAP) diagnosis supporting increased meperidine quantities of short-acting opioids, all NUCYNTA (tapentadol) short acting solid forms of the OPANA (oxymorphone) narcotic analgesics are limited to ONSOLIS (fentanyl) 120 tablets per 30 days for the purpose of maximizing the use of 4 BUREAU FOR MEDICAL SERVICES WEST VIRGINIA MEDICAID EFFECTIVE PREFERRED DRUG LIST WITH PRIOR AUTHORIZATION CRITERIA 10/1/12 This is not an all-inclusive list of available covered drugs and includes only managed categories. Refer to cover page for complete list of rules governing this PDL. Version 2012.7b THERAPEUTIC PREFERRED AGENTS NON-PREFERRED AGENTS PA CRITERIA DRUG CLASS oxycodone/ibuprofen longer acting medications to OXECTA (oxycodone) prevent unnecessary breakthrough OXYFAST (oxycodone) pain in chronic pain therapy. OXYIR (oxycodone) PANLOR (dihydrocodeine/ APAP/caffeine) PERCOCET (oxycodone/APAP) PERCODAN (oxycodone/ASA) PRIMLEV (oxycodone/APAP) ROXANOL (morphine) RYBIX ODT (tramadol) SUBSYS (fentanyl) NR
Recommended publications
  • Optum Essential Health Benefits Enhanced Formulary PDL January

    Optum Essential Health Benefits Enhanced Formulary PDL January

    PENICILLINS ketorolac tromethamineQL GENERIC mefenamic acid amoxicillin/clavulanate potassium nabumetone amoxicillin/clavulanate potassium ER naproxen January 2016 ampicillin naproxen sodium ampicillin sodium naproxen sodium CR ESSENTIAL HEALTH BENEFITS ampicillin-sulbactam naproxen sodium ER ENHANCED PREFERRED DRUG LIST nafcillin sodium naproxen DR The Optum Preferred Drug List is a guide identifying oxacillin sodium oxaprozin preferred brand-name medicines within select penicillin G potassium piroxicam therapeutic categories. The Preferred Drug List may piperacillin sodium/ tazobactam sulindac not include all drugs covered by your prescription sodium tolmetin sodium drug benefit. Generic medicines are available within many of the therapeutic categories listed, in addition piperacillin sodium/tazobactam Fenoprofen Calcium sodium to categories not listed, and should be considered Meclofenamate Sodium piperacillin/tazobactam as the first line of prescribing. Tolmetin Sodium Amoxicillin/Clavulanate Potassium LOW COST GENERIC PREFERRED For benefit coverage or restrictions please check indomethacin your benefit plan document(s). This listing is revised Augmentin meloxicam periodically as new drugs and new prescribing LOW COST GENERIC naproxen kit information becomes available. It is recommended amoxicillin that you bring this list of medications when you or a dicloxacillin sodium CARDIOVASCULAR covered family member sees a physician or other penicillin v potassium ACE-INHIBITORS healthcare provider. GENERIC QUINOLONES captopril ANTI-INFECTIVES
  • Pharmacology in MS Advanced Practice Management

    Pharmacology in MS Advanced Practice Management

    Pharmacology in MS Advanced Practice Management Heidi Maloni APRN, BC [email protected] Objectives • Discuss basic principles of pharmacology, pharmacokinetics and pharmacodynamics. • Describe the pharmacotherapeutics of drugs used in MS • Identify the role of advanced practice nurse in MS pharmacological management. Advanced Practice Pharmacology Background • Pharmacology: study of a drug’s effects within a living system • Each drug is identified by 3 names: chemical, generic, trade or marketing name N-4-(hydroxyphenyl) acetamide; acetaminophen; Tylenol sodium hypochlorite; bleach; Clorox 4-(diethylamino)-2-butynl ester hydrochloride; oxybutynin chloride; Ditropan • Drugs are derived from: plants, humans, animals, minerals, and chemical substances • Drugs are classified by clinical indication or body system APN Role Safe drug administration Nurses are professionally, legally, morally, and personally responsible for every dose of medication they prescribe or administer Know the usual dose Know usual route of administration Know significant side effects Know major drug interactions Know major contraindication Use the nursing process Pregnancy Safety • Teratogenicity: ability to produce an abnormality in the fetus (thalidomide) • Mutogenicity: ability to produce a genetic mutation (diethylstilbestrol, methotrexate) Pregnancy Safety Categories • A: studies indicate no risk to the fetus (levothyroxan; low dose vitamins, insulin) • B: studies indicate no risk to animal fetus; information in humans is not available (naproxen;acetaminophen; glatiramer
  • View / Download Pdf Version of This Article

    View / Download Pdf Version of This Article

    role of CALCIUM CHANNEL BLOCKERS in HYPERTENSION KEY POINTS ThIAZIDES ARE APPROPRIATE INITIAL THERAPY FOR MOST PEOPLE WITH HYPERTENSION Thiazides are appropriate initial therapy for most ▪ There is limited evidence of superiority of one antihypertensive people with hypertension. over another but evidence suggests that for most patients, ▪ Choice of other antihypertensives is decided by diuretics can be considered first, based on their effectiveness, individual patient factors. safety and low cost. ▪ Factors which potentially favour use of calcium channel blockers include arrhythmia (verapamil CHOICE OF ADDITIONAL ANTIHYPERTENSIVES only), angina, older age and high risk of stroke. IS DECIDED BY INDIVIDUAL PATIENT FACTORS ▪ Factors which may weigh against the use of Other agents may be chosen for individual patients based calcium channel blockers include potential drug on concurrent medical conditions, patient tolerability and interactions, and diltiazem and verapamil are drug interactions. Indications for treatment with different contraindicated in heart block and heart failure. antihypertensive agents are discussed in BPJ 6 (June 2007). ▪ Choice between the different calcium channel blockers depends on patient tolerability, co- morbidity and drug interactions. FACTORS FOR AND AGAINST THE USE OF CALCIUM chANNEL BLOCKERS Factors that potentially favour the use of calcium channel Factors favouring use of calcium channel blockers include arrhythmia (verapamil only), angina, or high blockers: risk of stroke. Verapamil can also be used post myocardial infarction if beta blockers are contraindicated or not tolerated. ▪ Hypertension with co-morbid angina In addition, calcium channel blockers may be more suitable than other agents for elderly people and those of African ▪ Hypertension with co-morbid arrhythmia 1 (verapamil only) descent.
  • Alcoholism Pharmacotherapy

    Alcoholism Pharmacotherapy

    101 ALCOHOLISM PHARMACOTHERAPY JOSEPH R. VOLPICELLI SUCHITRA KRISHNAN-SARIN STEPHANIE S. O’MALLEY Alcoholism remains one of the most common and signifi- PHARMACOLOGIC TREATMENTS FOR cant medical problems in the United States and internation- ALCOHOL DETOXIFICATION ally. For example, in the United States, over 4% of the general population is alcohol dependent and another 5 to The first step in the pharmacologic treatment of alcoholism 10 million people drink hazardously at least several times is to help patients safely detoxify from alcohol. Although per month (1). The economic and medical costs of alcohol- historically, alcohol detoxification has occurred in inpatient ism and alcohol abuse continue to escalate. Most recent setting, increasingly alcohol detoxification is being con- figures put the economic costs of alcohol-related expenses ducted in ambulatory settings. Except in the case of medical at $176 billion annually in the United States (2). This in- or psychiatric emergencies, outcome studies generally show cludes the economic costs of increased health care expenses, that successful detoxification can safely and effectively be lost productivity at work, and legal expenses. Similarly, al- carried out in ambulatory setting using medications such though there have been some reductions in the number of as benzodiazepines (5,6). In addition, the use of anticonvul­ motor vehicle deaths attributed to excessive alcohol drink- sants has received recent interest. ing, the overall number of alcohol-related annual deaths is 105,000 in the United States (3). Benzodiazepines Current psychosocial approaches to alcohol addiction are moderately effective, with perhaps as many as half the pa- Benzodiazepines are �-aminobutyric acid (GABA) agonists tients receiving treatment becoming abstinent or signifi- that metaanalysis of placebo-controlled double-blind studies cantly reducing episodes of binge drinking (4).
  • Antiparasitic Properties of Cardiovascular Agents Against Human Intravascular Parasite Schistosoma Mansoni

    Antiparasitic Properties of Cardiovascular Agents Against Human Intravascular Parasite Schistosoma Mansoni

    pharmaceuticals Article Antiparasitic Properties of Cardiovascular Agents against Human Intravascular Parasite Schistosoma mansoni Raquel Porto 1, Ana C. Mengarda 1, Rayssa A. Cajas 1, Maria C. Salvadori 2 , Fernanda S. Teixeira 2 , Daniel D. R. Arcanjo 3 , Abolghasem Siyadatpanah 4, Maria de Lourdes Pereira 5 , Polrat Wilairatana 6,* and Josué de Moraes 1,* 1 Research Center for Neglected Diseases, Guarulhos University, Praça Tereza Cristina 229, São Paulo 07023-070, SP, Brazil; [email protected] (R.P.); [email protected] (A.C.M.); [email protected] (R.A.C.) 2 Institute of Physics, University of São Paulo, São Paulo 05508-060, SP, Brazil; [email protected] (M.C.S.); [email protected] (F.S.T.) 3 Department of Biophysics and Physiology, Federal University of Piaui, Teresina 64049-550, PI, Brazil; [email protected] 4 Ferdows School of Paramedical and Health, Birjand University of Medical Sciences, Birjand 9717853577, Iran; [email protected] 5 CICECO-Aveiro Institute of Materials & Department of Medical Sciences, University of Aveiro, 3810-193 Aveiro, Portugal; [email protected] 6 Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand * Correspondence: [email protected] (P.W.); [email protected] (J.d.M.) Citation: Porto, R.; Mengarda, A.C.; Abstract: The intravascular parasitic worm Schistosoma mansoni is a causative agent of schistosomiasis, Cajas, R.A.; Salvadori, M.C.; Teixeira, a disease of great global public health significance. Praziquantel is the only drug available to F.S.; Arcanjo, D.D.R.; Siyadatpanah, treat schistosomiasis and there is an urgent demand for new anthelmintic agents.
  • Comparison of Different Alpha-Blocker Combinations in Male Hypertensives with Refractory Lower Urinary Tract Symptoms

    Comparison of Different Alpha-Blocker Combinations in Male Hypertensives with Refractory Lower Urinary Tract Symptoms

    대한남성과학회지：제 29 권 제 3 호 2011년 12월 Korean J Androl. Vol. 29, No. 3, December 2011 http://dx.doi.org/10.5534/kja.2011.29.3.242 Comparison of Different Alpha-blocker Combinations in Male Hypertensives with Refractory Lower Urinary Tract Symptoms Keon Cheol Lee1, Jong Gu Kim2, Sung Yong Cho1, Joon Sung Jeon1, In Rae Cho1 Department of Urology, 1Inje University Ilsanpaik Hospital, Goyang, 2Happy Urology Clinic, Ansan, Korea =Abstract= Purpose: We compared the efficacy and safety profiles of dose increase, traditional combination methods, and combining different alpha blockers in hypertensive males with lower urinary tract symptom (LUTS) refractory to an initial dose of 4 mg doxazosin. Materials and Methods: Between 2000 and 2005, 374 male patients with LUTS and hypertension unresponsive to 4 weeks of 4 mg doxazosin were enrolled. The subjects were randomly classified into 3 groups, 8 mg/day of doxazosin (D group), 4 mg of doxazosin plus 0.2 mg/day of tamsulosin (DT group), and 4 mg doxazosin plus 5 mg/day finasteride (DF group). Patients were evaluated based on their International Prostate Symptom Score (IPSS), quality of life (QOL), uroflowmetry and blood pressure (BP) and adverse events (AEs) at the baseline and 3 and 12 months after treatment. Results: The 269 patients (71.9%) were followed for at least 1 year (D group n=84, DT group n=115, and DF group n=70). The clinical parameters before and after initial 4 mg/day doxazosin were not different among the 3 groups. IPSS improvement after 3 months and maximal flow rate (Qmax) improvement after 3 and 12 months were significantly higher in the D and DT groups than the DF group (p＜0.05).
  • Airway Receptors

    Airway Receptors

    Postgraduate Medical Journal (1989) 65, 532- 542 Postgrad Med J: first published as 10.1136/pgmj.65.766.532 on 1 August 1989. Downloaded from Mechanisms of Disease Airway receptors Peter J. Barnes Department of Thoracic Medicine, National Heart and Lung Institute, Dovehouse Street, London SW3 6L Y, UK. Introduction Airway smooth muscle tone is influenced by many indirect action which, in part, is due to activation of a hormones, neurotransmitters, drugs and mediators, cholinergic reflex, since the bronchoconstriction may which produce their effects by binding to specific be reduced by a cholinergic antagonist. Other surface receptors on airway smooth muscle cells. mediators may have a bronchoconstrictor effect Bronchoconstriction and bronchodilatation may which, in the case of adenosine, is due to mast cell therefore be viewed in terms of receptor activation or mediator release,2 or in the case of platelet-activating blockade and the contractile state of airway smooth factor due to platelet products.3 muscle is probably the resultant effect of interacting excitatory and inhibitory receptors. Epithelial-derived relaxantfactor It is important to recognize that airway calibre is not only the result of airway smooth muscle tone, but in Recently there has been considerable interest in the asthma it is likely that airway narrowing may also be possibility of a relaxant factor released from airway explained by oedema of the bronchial wall (resulting epithelial cells, which may be analogous to relaxant factor.4 The presence of from microvascular leakage) and to luminal plugging endothelial-derived by copyright. by viscous mucus secretions and extravasated plasma airway epithelium in bovine airways in vitro reduces proteins, which may be produced by a 'soup' of the sensitivity to and maximum contractile effect of mediators released from inflammatory cells, including spasmogens, such as histamine, acetylcholine or mast cells, macrophages and eosinophils.
  • 2021 Formulary List of Covered Prescription Drugs

    2021 Formulary List of Covered Prescription Drugs

    2021 Formulary List of covered prescription drugs This drug list applies to all Individual HMO products and the following Small Group HMO products: Sharp Platinum 90 Performance HMO, Sharp Platinum 90 Performance HMO AI-AN, Sharp Platinum 90 Premier HMO, Sharp Platinum 90 Premier HMO AI-AN, Sharp Gold 80 Performance HMO, Sharp Gold 80 Performance HMO AI-AN, Sharp Gold 80 Premier HMO, Sharp Gold 80 Premier HMO AI-AN, Sharp Silver 70 Performance HMO, Sharp Silver 70 Performance HMO AI-AN, Sharp Silver 70 Premier HMO, Sharp Silver 70 Premier HMO AI-AN, Sharp Silver 73 Performance HMO, Sharp Silver 73 Premier HMO, Sharp Silver 87 Performance HMO, Sharp Silver 87 Premier HMO, Sharp Silver 94 Performance HMO, Sharp Silver 94 Premier HMO, Sharp Bronze 60 Performance HMO, Sharp Bronze 60 Performance HMO AI-AN, Sharp Bronze 60 Premier HDHP HMO, Sharp Bronze 60 Premier HDHP HMO AI-AN, Sharp Minimum Coverage Performance HMO, Sharp $0 Cost Share Performance HMO AI-AN, Sharp $0 Cost Share Premier HMO AI-AN, Sharp Silver 70 Off Exchange Performance HMO, Sharp Silver 70 Off Exchange Premier HMO, Sharp Performance Platinum 90 HMO 0/15 + Child Dental, Sharp Premier Platinum 90 HMO 0/20 + Child Dental, Sharp Performance Gold 80 HMO 350 /25 + Child Dental, Sharp Premier Gold 80 HMO 250/35 + Child Dental, Sharp Performance Silver 70 HMO 2250/50 + Child Dental, Sharp Premier Silver 70 HMO 2250/55 + Child Dental, Sharp Premier Silver 70 HDHP HMO 2500/20% + Child Dental, Sharp Performance Bronze 60 HMO 6300/65 + Child Dental, Sharp Premier Bronze 60 HDHP HMO
  • Beyond Lithium in the Treatment of Bipolar Illness Robert M

    Beyond Lithium in the Treatment of Bipolar Illness Robert M

    Beyond Lithium in the Treatment of Bipolar Illness Robert M. Post, M.D., Mark A. Frye, M.D., Kirk D. Denicoff, M.D., Gabriele S. Leverich, L.C.S.W., Tim A. Kimbrell, M.D., and Robert T. Dunn, M.D. Dramatic changes have recently occurred in the availability lamotrigine, gabapentin, and topiramate have unique of treatment options for bipolar illness. Second generation mechanisms of action and deserve further systematic study, mood stabilizing anticonvulsants carbamazepine and as does the potential role for nonconvulsive brain valproate are now widely used as alternatives or adjuncts to stimulation with repeated transcranial magnetic lithium. High potency benzodiazepines are also used as stimulation (rTMS). These and a host of other potential alternatives to typical neuroleptics, and now atypical treatment options now require a new generation of clinical neuroleptics are demonstrating efficacy and better side- trials to help identify clinical and biological markers of effects profiles than the typicals. Thyroid augmentation response and optimal use alone and in complex combination strategies and dihydropyridine L-type calcium channel therapeutic regimens. [Neuropsychopharmacology blockers require further clinical trials to define their role. 19:206–219, 1998] Published by Elsevier Science Inc. Putative third generation mood stabilizing anticonvulsants KEY WORDS: Carbamazepine; Valproate; Calcium channel al. 1989; O’Connell et al. 1991; Denicoff et al. 1997); a blockers; Lamotrigine; Gabapentin; rTMS history of co-morbid substance abuse; and those pa- tients with a history of head trauma or other such medi- There is increasing recognition of the inadequacy of cal co-morbidities as multiple sclerosis, etc. “lithium treatment” in bipolar illness, even with ad- In addition, it is recognized that patients with initial junctive antidepressants and neuroleptics (Maj et al.
  • Provider- Pain Quick Reference Guide

    Provider- Pain Quick Reference Guide

    A QUICK REFERENCE GUIDE (2019) PBM Academic Detailing Service Posttraumatic Stress Disorder A VA Clinician's Guide to Optimal Treatment of Posttraumatic Stress Disorder (PTSD) VA PBM Academic Detailing Service Real Provider Resources Real Patient Results Your Partner in Enhancing Veteran Health Outcomes VA PBM Academic Detailing Service Email Group [email protected] VA PBM Academic Detailing Service SharePoint Site https://vaww.portal2.va.gov/sites/ad VA PBM Academic Detailing Public Website http://www.pbm.va.gov/PBM/academicdetailingservicehome.asp Table of Contents Abbreviations . 1 PTSD Treatment Decision Aid . 3 VA/DoD 2017 Clinical Practice Guideline: Treatment of PTSD . 4 First-Line Treatment: Trauma-focused Psychotherapies with the Strongest Evidence . 5 First-Line Treatment: Trauma-Focused Psychotherapies with Sufficient Evidence . 6 Comparison of Antidepressants Studied in PTSD . 7 Recommended Antidepressant For PTSD: Dosing . 9 Additional Medications Studied in PTSD: Dosing . 11 Switching Antidepressants . 12 Antidepressants and Sexual Dysfunction . 14 i TOC (continued) Sexual Dysfunction Treatment Strategies . 16 Antidepressants and Hyponatremia . 17 Additional Pharmacotherapy Options for Veterans Refractory to Standard Treatments . 19 Discussing Benzodiazepine Withdrawal . 21 Prazosin Tips . 25 Prazosin Precautions . 26 Managing PTSD Nightmares in Veterans with LUTS Associated with BPH . 27 Other Medications Studied in PTSD-Related Nightmares . 29 References . 30 ii Abbreviations Anti-Ach = anticholinergic
  • Cvs Caremark ® Maintenance Drug List

    Cvs Caremark ® Maintenance Drug List

    CVS CAREMARK® MAINTENANCE DRUG LIST EFFECTIVE AS OF 03/03/2021 Maintenance drugs are prescriptions commonly used to treat conditions that are considered chronic or long-term. These conditions usually require regular, daily use of medicines. Examples of maintenance drugs are those used to treat high blood pressure, heart disease, asthma and diabetes. Due to the large number of available medicines, this list is not all inclusive. Please note that this list does not guarantee coverage and is subject to change. Your prescription benefit plan may not cover certain products or categories, regardless of their appearance on this list. Where a generic is available, it is listed by the generic name. If no generic is available, then the brand name appears. This list represents brand products in CAPS and generic products in lower case italics. If you have questions about your prescription benefits, please log on to your account at Caremark.com or call Customer Care at the number on your ID card. Allergies pentoxifylline Depression desloratidine prasugrel bupropion levocetirizine ticlopidine citalopram ZONTIVITY desvenlafaxine Alzheimer’s Disease duloxetine donepezil Cancer escitalopram galantamine anastrozole fluoxetine memantine exemestane fluvoxamine rivastigmine letrozole mirtazapine NAMZARIC tamoxifen nefazodone toremifene paroxetine Antipsychotics sertraline trazodone Aripiprazole Contraceptives venlafaxine brexipiprazole ethinyl estradiol-desogestrel APLENZIN loxapine ethinyl estradiol-drospirenone FETZIMA olanzapine ethinyl estradiol-ethynodiol
  • Oral Phentolamine: an Alpha-1, Alpha-2 Adrenergic Antagonist for the Treatment of Erectile Dysfunction

    Oral Phentolamine: an Alpha-1, Alpha-2 Adrenergic Antagonist for the Treatment of Erectile Dysfunction

    International Journal of Impotence Research (2000) 12, Suppl 1, S75±S80 ß 2000 Macmillan Publishers Ltd All rights reserved 0955-9930/00 $15.00 www.nature.com/ijir Oral phentolamine: an alpha-1, alpha-2 adrenergic antagonist for the treatment of erectile dysfunction I Goldstein1 1Department of Urology, Boston University School of Medicine, Boston, MA, USA Phentolamine mesylate is an alpha-1 and alpha-2 selective adrenergic receptor antagonist which has undergone clinical trials for erectile dysfunction treatment. Biochemical and physiological studies in human erectile tissue have revealed a high af®nity of phentolamine for alpha-1 and alpha-2 adrenergic receptors. Based on pharmacokinetic studies, it is suggested that 30±40 min following oral ingestion of 40 or 80 mg of phentolamine (Vasomax), the mean plasma phentolamine concentrations are suf®cient to occupy the alpha-1 and -2 adrenergic receptors in erectile tissue and thereby result in inhibition of adrenergic-mediated physiologic activity. In large multi-center, placebo-controlled pivotal phase III clinical trials, the mean change in the erectile function domain of the International Index of Erectile Function scores (Questions 1±5 and 15) from screening to the end of treatment was signi®cantly higher following use of active drug (40 mg and 80 mg) compared to placebo. Three to four times as many patients receiving phentolamine reported being satis®ed or very satis®ed compared with those receiving placebo. At doses of 40 mg and 80 mg respectively, 55% and 59% of men were able to achieve vaginal penetration with 51% and 53% achieving penetration on 75% of attempts.