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Index of General Terms 395

Index of General Terms

3D clusters (in cytology) polymorphous low grade 131 adiposis dolorosa 281 mesothelial 360 prostatic 220, 222, 224 adnexal tumours 292–4 urine 365 adenoid adrenal medullary chromaffin adenocarcinoma 361 basal 234 paraganglioma 276 1-antitrypsin 157 basal epithelioma 234 adrenal pathology 53–4, 275–7, 383 acantholytic cystic carcinoma 131, 369 adrenocortical adenoma 275–6 285 pharyngeal tonsil 38 adrenocortical carcinoma (ACC) acanthoma 282, 283, 292 adenoma 130–1, 200 275–6 accessory auricles 199 adrenocortical 275–6 adrenocorticotrophic hormone acetic acid artefact 357 basal cell 130–1, 223 (ACTH) 275, 278 achalasia of the cardia 135 bile duct 172 adult achondroplasia 330 bronchioalveolar 91 249 acinar cell carcinoma/dysplasia 177 Brunner’s gland 142 large bile duct obstruction 164 acinar zones (of liver) 156 canalicular 131 renal tumours 49 acinic cell carcinoma 132, 369 duct 264 respiratory distress syndrome 383 acquired immunodeficiency dysplasia 149–50 T-cell leukaemia 115–16 syndrome (AIDS, see also HIV) flat 149–50 advanced practitioners 359 165, 306–7, 346–7, 364 follicular 268–9 adventitious bursa 342 acral naevus 288 gastric 138 AFP 19 acrodermatitis enteropathica 304 hepatocellular 169–70 age-related changes 68, 75, 196–7, ACTH 275, 278 hyalinising trabecular 271 201 actinic malignum 235 age-related macular degeneration keratosis 283 metanephric 216 (AMD) 196–7 lentigo 288–9 microcystic 177 Agenda for Change 24–5 reticuloid 299 nephrogenic 218 aggressive Actinomyces spp. 343–344, 22, 239, of the nipple 259–60 angiomyxoma 317 357, 371 parathyroid 274 osteoblastoma 335 acute Pick’s 227 AIDS cholangiopathy 165 cholecystitis 173–4 pleomorphic salivary 130, 368 AIDS-associated malignancies diffuse proliferative polypoidal 149–50 347 glomerulonephritis 202 renal 216 AIDS-defining illnesses (ADI) 346, disseminated encephalomyelitis 183 serous microcystic 177 364 endometriosis 239 serrated 149–50 AIN 152 febrile neutrophilic dermatosis 300 sporadic 149–50 air embolism 390 haemorrhagic leucoencephalitis 183 adenomatous Albers-Sch¨onberg marble bone haemorrhagic hyperplasia (lung) 91 disease 330 leucoencephalomyelitis 183 hyperplasia (prostate) 220–1 Alcian blue 12 haemorrhagic leucoencephalopathy nodules (liver) 171 alcoholic 183 polyps 138, 149–50, 220 fixatives 7 hepatitis 158–9 gastropathy 137 lymphoblastic leukaemia 16, 97, atypical polypoid 239, 242 hepatitis 157 101, 103–5, 228, 253 biliary tree 173 steatohepatitis 157 myeloid leukaemia 103, gallbladder 174 alimentary tract 126–55 4, 16, 99–104, 107–8, 123, 300 uterus 239 alkaline phosphatase (ALP) 11, 15, pancreatitis 175 adenosarcoma 242–3 53, 332, 336, 337 pouchitis 147 COPYRIGHTEDtamoxifen and 238, 254 MATERIALALL 16, 97, 101, 103–5, 228, 253 pyelonephritis 206 vs. endometrial stromal tumours 242 allograft rejection see transplants radiation effects 305 vs. granulosa cell tumour 249 alopecia 295 rheumatic fever 76–7 adenosis ALP 11, 15, 53, 332, 336, 337 tubular necrosis 206 atypical apocrine 262, 373 Alport’s disease 205 villitis 63 microglandular 262 alveolar adamantinoma 335 prostate 220–1 capillary dysplasia 56 adenocarcinoma 91–2, 219, 361 sclerosing (breast) 262 pathology 58 basal cell 130–1 sclerosing (prostate) 221 radial counts 393 bronchial 369–70 sclerosing (salivary) 134 soft part sarcoma 323 ductal 176 vaginal 232 Alzheimer’s disease 181 endometrioid 92 adenosquamous carcinoma (ASC) 92 AMD 196–7 invasive 234–5 ADH 258–9 ameloblastic fibroma 128–9 minimal deviation 235 adipose 313–15 ameloblastoma 128

Diagnostic Criteria Handbook in Histopathology: A Surgical Pathology Vade Mecum by Paul J. Tadrous Copyright C 2007 by John Wiley & Sons, Ltd. JWBK208-IND-II August 12, 2008 16:22 Char Count= 0

Index of General Terms 396

AML 103, 4, 16, 99–104, 107–8, 123, antiphospholipid antibody syndrome ASH 157 300 61–2, 351 Askin tumour of chest wall 58 amnion nodosum 63 aortic dissection 73 Aspergillus spp. 22, 345, 370 ampulla of Vater 46 aphthae 126–7, 144–5 asthma 86 amputation neuroma 317 apical granuloma 128 astrocytoma 185 amyloid 11 apocrine carcinoma 293 asymptomatic proteinuria 201 angiopathy 72 aponeuroses 323–4 atherosclerotic aneurysms 72 colonic 146 appendix 46, 152 atrophy 358 eye 194 applied anatomy 36–43 atypical skin 300 appraisals 32 acinar cell nodules 177 tumour 94, 194 arachnoid nodules 94 adenomatous hyperplasia 91, 220–1 anal canal 152 ARDS 383 adenomatous nodules 171 anal intra-epithelial neoplasia (AIN) Arias-Stella reaction 232, 236, 237, decubital fibroplasia 311 152 253 ductal hyperplasia 258–9 analgesic nephropathy 206 arrhythmogenic right ventricular fibroxanthoma 325 anaphylaxis 382 dysplasia (ARVD) 78, 385 haemangioma of the breast 320 anaplastic artefact(s) hyperplasia 51, 238 astrocytoma 185 acetic acid 357 lipoma 313 carcinoma 272, 368 air bubbles (vs. air embolism) 390 lobular hyperplasia 262 large cell lymphoma 105, 109, 116 alcohol fixation 7 nodular proliferations in a meningioma 186 birefringent particles (in synovial congenital naevus 288 myeloma 109 fluid) 375 polypoid adenomyoma 239 oligo/oligoastrocytoma 186 capsule/halo (in Histoplasma) 345 small acinar proliferations 222 seminoma 225 cirrhosis and 161 vascular lesions post radiotherapy Wilms’ tumour 60 cracks (in FCL) 112 320 anatomy 36–43 crush (in carcinoid/SmCC/spinal aural polyp 199, 319 ancillary techniques 362–3 cord) 93, 389 autoimmune ancillary tests 387 dyscohesion (in breast FNA) 371, diseases 86–7 androgen blockade therapy 224 373 hepatitis 161 aneurysmal bone cysts (ABC) 331, dysplasia vs. 136 pancreatitis 175 333 erosion vs. 127 plexopathy 154 aneurysms 72–3 FNA / needle track 265, 269 sialadenitis 132–3 angina 75 formalin fixation (unbufferred) 7, autopsy 3, 23, 377–94 angioblastoma of Nakagawa 319 383 limited 386–7 angiocentric frozen section 4 performance lymphoid proliferations 91 ice crystal (in muscle) 43, 189 recommendations/guidance 378 T-cell lymphoma 115 iodine (and CIN) 233 perinatal 392–3 angiodysplasia 148 liver 156 see also postmortem angiofollicular lymph node mercurial fixation 16 autosomal dominant polycystic hyperplasia 119–20 nuclear clearing (due to kidney disease (ADPCKD) angiography 386 biotin/fixation) 267, 270, 272 212–13 angioimmunoblastic RBCs in alveoli 87 autosomal recessive polycystic kidney lymph node reaction 115 retraction (in lacunar cells) 4, 117 disease 213 lymphadenopathy with sampling (in muscle Bx) 189 avascular dysproteinaemia 115 sclerosing HCC (footnote) 171 necrosis 330 T-cell lymphoma 115 sickling of RBCs 383 villi 62 circumscriptum 285 smearing (vs. vascular invasion) 205 angioleiomyolipoma 314 spindling (in Ewing’s) 336 B-cell angiolipoma 313 tangiential sectioning 205 lymphoma 110–14, 302 angiolymphoid hyperplasia with thick section (syncytial knots) 61 persistent polyclonal lymphocytosis eosinophilia 318 arterial 101 angiomatosis 319–23 dissection 73 reactions 109 angiomyofibroblastoma 317 embolism 390 bacillary angiomatosis 319 angiomyolipoma 216, 314 pathology 68, 69 bacilli 343 angiomyxoma 317–18 pulmonary hypertension 88 bacterial 320–1 arteriohepatic dysplasia 164 colitis 143 ankylosing spondylitis 194 arterioles/arteriolosclerosis 68, 69 infection 343–4 anti-rejection drug toxicity 209–10 arteriosclerosis 68 balanitis xerotica obliterans (BXO) antibodies arteritis 44, 69, 70 215 anticardiolipin 351 arthritis 340–1 balloon cells 197 antiphospholipid antibody articular pathology 339–42 Banff grading 209, 208, 165 syndrome 61–2, 351 ARVD 78, 385 Barium 148, 341, 32 layering methods 9 ASAP/ASAPUS 222 Barrett’s, 135, 45 site selective 363 asbestos bodies 86, 48, 371 epithelium 135 anticardiolipin antibody 351 asbestosis 85–6 dysplasia 136 antigens 19, 107–9 ascending cholangitis 166–7 oesophagus 135 JWBK208-IND-II August 12, 2008 16:22 Char Count= 0

Index of General Terms 397

Bartholin gland cysts 232 1-antitrypsin 157, 170 pathology 329–39 Bartonella spp. 167 aortic 11 sarcoma 53 basal cell asbestos 86, 48, 371 tumours 332–9 adenocarcinoma 130–1 Aschoff 76–7 BOOP 85 adenoma 130–1, 223 asteroid 194 borderline adenomatosis 223 Barr 353 cutaneous T-cell proliferations 302 carcinoma 48, 223, 284, 292 blue 84, 370 mucinous tumours 245 hyperplasia 223 Call-Exner 249, 252 nuclear changes 354, 358 immunohistochemistry 18 Call-Exner-like 227 seminoma 225 papilloma 282–3 carotid 11 serous tumours of the peritoneum basal ganglia degenerations 182 Civatte 297, 306 255 basal-like carcinoma (breast) 265 colloid 300 225 basement membranes 11 Councilman 159, 163, 166 Borst-Jadassohn phenomenon 282 Baylisascaris spp. 349 Creola 369 Bouin’s fixative 7 BCC 48, 223, 284, 292 cytoid 185, 195 Bowel Cancer Screening Program 32 BCDA 136 Donovan 109, 343 Bowenoid actinic keratosis 283 Becker’s muscular dystrophy 191 Dutcher 104, 361, 362 Bowenoid papulosis 229 Becker’s pigmented hairy epidermal elementary 185 Bowen’s disease 229, 283 naevus 287 embryoid 252 BPOP 333 Beh¸cet’s ferruginous 86 brain 36, 187–8, 383, 388 arthritis 341 fibrous 278 breast colitis 144, 145 foreign 101 angiomatosis 319 disease 194 fruiting 345 atypical haemangioma 320 benign Gamna-Gandy 79, 122 atypical vascular lesions 320 breast lesions 265–6 giant lamellar 91 basal-like carcinoma 265 familial chronic pemphigus 304 haematoxyphile 204 benign lesions 265–6 familial haematuria 205 Herring 277 carcinoma 17, 52, 260–262, 265 fibrous histiocytoma 326 Hirano 181 cytopathology 361, 371–4 hypertension 68 inclusion (polyglucosan) 153 lymphoma/pseudolymphoma lesions 371, 373 inclusion (viral) 10 and see specific 263 lymph node inclusions 118 viruses myofibroblastoma 312 lymphoepithelial cysts 133 jugulotympanic 279 pathology 118, 258–66 lymphoepithelial lesions 132–3 Leishman-Donovan 343 Breast Screening Program 32 melanocytic lesions 287 Lewy 181, 182, 135 Brenner tumours 247 metastasizing leiomyoma 242 loose 340–1 bridging necrosis 158 osteoblastoma 335 lymphoglandular 373 brittle bone disease 331 ovarian cysts 374 lyssa 346 broad ligament 243 paratesticular tumours 228–9 M- 153 Broders’ grade 284 prostatic tissue 223–4 Mallory 156–7, 159–60, 162–4, bronchial adenocarcinoma renal tumours 216 169–72 369–70 bile duct(s) mammillary 36, 388 bronchiectasis 83 adenofibroma 172 Masson 84–5, 89 bronchioalveolar adenoma 91 adenoma 172 Meissner 287, 316 bronchioalveolar carcinoma (BAC) cut-up/reporting 46 Michaelis-Gutmann 214 91–2, 369 164 myeloid 206 bronchiolitis obliterans (OP, COP, normal ranges and BD loss 156, 162 Negri 346 BOOP) 85 pathology 162–5 pale 172 bronchitis 83, 85–6 bile pigments 13 papillary mesenchymal 292 bronchography 386 biliary Pick 181 Brucella spp. 343, 22, 101, 122, 167, atresia 164 psammoma see psammoma bodies 195, 215, 383 cystic lesions 172 rice 340 Brunner’s gland hyperplasia, nodules tract 156, 366, 390 Rushton 128 and adenoma 142 Binswanger’s disease 182 Russell 104, 10, 82, 199, 300 BSCC guidelines 359 biomedical scientists (BMS) 24–5 Schaumann 147 BSG catergorisation for chronic biopsies 43–52 Schiller-Duval 226 hepatitis 160 breast core 265 spironolactone 275 budgetary control 26–8 bizarre parosteal osteochondromatous tactoid 316 Buerger’s disease 71 proliferation (BPOP) 333 tingible 15 bullous pemphigoid 304 BK polyoma virus 365 Verocay 315 Burkitt’s lymphoma 113–14 bladder 214–15, 219, 220 Wagner-Meisner 287 bursa 342 blistering diseases (of skin) 303–5 Weibel-Palade 317, 285 BXO 215 blue naevi 287 body weight 391 blue rubber bleb naevus 281 bone 11 C-cell hyperplasia 271 BMS 24–5 cysts 333 CA-19.9 19 body mass index (BMI) xiv, 158, 391 infarcts 330 CA-125 19 bodies marrow 99–106 cadherins 261 JWBK208-IND-II August 12, 2008 16:22 Char Count= 0

Index of General Terms 398

calcification various organs 96, 135, 139, 174, bladder 215, 220 breast 259, 265 272, 276 bone marrow 103, 99, 104 cornea 196 and 17 breast 265, 266 front (in bone) 329, 8 cardiac cervical smear 358 kidney 205 allograft/transplant rejection 77–8 colon 148 59 death 76, 78, 385–6 dysplasia vs. 138, 148, 220 63 fibroma 78 kidney (TMA) 207 psammomatous see psammoma mucosa 126 liver 168, 169, 171 bodies myxoma 78 lung 88, 92 skin 300 valves 386, 391 mesothelial cells 360 calcifying wall thickness 391 neoadjuvant () 151, epithelial odontogenic tumours 129 Carney complex/syndrome 280 47 epithelioma of Malherbe 293 Caroli disease/syndrome 163 neoadjuvant (oesophageal cancer) fibrous pseudotumour 324, 310 cartilage 329, 340 136 variants of sex cord tumours 227, caseation in the skin 300 osteosarcoma 336 251 CASTLE 272, 273 ovary (teratoma) 252 calciphylaxis 300, 303 Castleman’s disease 119–20 sarcoma grading and 327, 53 calcineurin inhibitors 209–10 casts (in urine) 365 skin 306 calcium cataracts 196 small bowel 141, 142 pyrophosphate deposition disease catecholamines 11 testis 224, 226 340, 375 Category 3 Hazard Group 22, 383–4 urine cytology 365 staining 11 CCAM 82–3 vascular effects (TMA) 207 calculi (urinary cytology and) 365 CD antigens 16, 107–8 see also the chilblains 300 Caldicott Guardians 31 Index of Molecules Chlamydia spp. 344 Calman Report 25–6 CD10 16, 107 endometritis 239 Calman-Hine Report 29–30, 33 CD30 +ve infiltrates in skin 302 gay bowel syndrome and 346 canalicular adenoma 131 CD99 16 keratoconjunctivitis 195 cancer networks 29–30 CD117 16, 140–1 vs. Kikuchi’s disease 119 Cancer Peer Review 30 CEA 19 and see the Index of cholangiocarcinoma 172, 173 Candida albicans 345, 354 Molecules cholangiolitis lenta 166 in AIDS 307, 346 cellular cholestasis 162 in CVID 142, 351 blue naevus 287 cholesteatoma 199 candidiasis haemangioma 318 chondroblastoma 338 vs. oral dysplasia 129 leiomyoma 241 chondrodermatitis nodularis helicis vs. oral hairy leukoplakia 133 lesion, advise excision (thyroid) 367 199 cannabinoids 89 myxoma 326 chondroid cap polyp 149 Schwannoma 315 lipoma 313–14 capillaries 68, 69 cellularity syringoma 294 carbohydrates 11 bone marrow 99 chondromyxoid fibroma 338 carboxylated mucins 12 cervical smear 353 chondrosarcoma 338–9 (CEA) 19 glomerulus 201 chorangioma/osis 62 and see the Index of Molecules central chordoma 184 carcinoid tumours 93, 139–40, 152, nervous system 43, 181–8 (ChC) 65–6, 252 251, 252–3, 271, 279, 370 neurocytoma 187 chorista 193 carcinoma osteosarcoma 336–7 choristoma 193 alimentary tract 127, 129–32, 136, pontine myelinolysis 381 choroid plexus tumours 188 138–9, 151 papilloma 264 chromaffin reaction 11 cytopathology 361–3 centronuclear myopathy 191 chromaffinoma 276 ear 200 cerebral cortex (layers of) 36, 182 chromophil carcinoma 217 ex pleomorphic adenoma 130 (footnote 1) chromophobe carcinoma 217–18 gallbladder 174 cerebrospinal fluid (CSF) 364 chronic gynaecological 233–4 ceruminal gland 200 arthritis 194 in situ 175, 219–20, 258 cervical bronchitis 83 liver 171–2 carcinoma 233–4 bullous dermatosis of childhood 305 pancreas 175, 177 glandular intraepithelial neoplasia discoid lupus erythematosus 297–8 segregans 285 234–6, 356, 359 endometriosis 239 showing thymus-like elements 272, neoplasia 51 gastritis 137 273 squamous intraepithelial neoplasia glomerulonephritis 202 urological 216–24 233–4, 356, 359 hepatitis 159–61, 166, 167 see also specific pathologies smears 353–5 idiopathic myelofibrosis 102 carcinosarcoma Cervical Screening Program 32 inflammatory arthropathies 340 lung 92 cervix uteri 233–6, 353–9 inflammatory bowel disease 56, mesothelioma vs. 89 CGIN 234–6, 356, 359 113, 143–7, 150–1 ovary 248 Chagas’ disease 76 lymphocytic leukaemia 110, 114, tamoxifen and 254 chalazion 194 105, 107–10, 114, 124, 362, 4, uterus 243 chemotherapy 47, 113, 167, 198, 304, 346, 350 JWBK208-IND-II August 12, 2008 16:22 Char Count= 0

Index of General Terms 399

myeloid leukaemia 103–4, 123 infective 143 conjunctivitis 194–5, 344, 348 pancreatitis 175 ischaemic 146, 143, 191 connective tissue diseases 70–1, 86–7, pyelonephritis 213 lymphocytic 146 135, 194–5, 204–5, 297–8, 299, radiation effects (vessels, GIT, microscopic 146 301, 340–1 bladder, skin) 72, 148, 215, 305–6 necrotising entero 56 consent 3, 377 pouchitis 147 non-specific 146 contact rheumatic fever valve disease 77 obstructive 146 granuloma of the true cord 82 thyroiditis 268 pseudomembranous 143, 386 ulcers 82 villitis 63 radiation 148 contaminants (cervical smear) 354 Churg-Strauss vasculitis 71 scorpion sting 191 Control of Substances Hazardous to CIBD 56, 113, 143–7, 150–1 segmental 146, 145 Health Regulations 2002 cicatricial pemphigoid 304 snake bite 191 (COSHH) 22 ciliary body 195 ulcerative 144 conventional renal cell carcinoma ciliated metaplasia 240 collagen 11, 332 216–17 CIN 233–4, 356, 359 collagenous colitis (CC) 146 copper 156–7, 12, 160, 162, 172, 196 cirrhosis 162–3, 169 collagenous gastritis 137 cornea guttata 196 cirsoid aneurysms 72 collecting duct carcinoma 217 corneal stromal deposits 196 CIS see carcinoma in situ colloid Coronial system 378–87 CJD 11, 22, 182, 378, 381, 383, 384–5 carcinoma 373 corpus CK 14–15, 327 and see Index of goitre 367 carcinoma 240–1 Molecules milium deposits 300 luteum cysts 374 Clark levels (staging) 291 colloidal gold 9 uteri 236–43 classical colon 41, 126 COSHH 22 acute hepatitis 158 colorectal Coxiella burnetii 343, 167 seminoma 225 carcinoma 17, 46–7, 151 CPA UK Ltd 28, 33 clear cell sentinel nodes 118 crack lung 89 acanthoma 283 columnar cell carcinoma 272 craniopharyngioma 184 carcinoma 247 columnar cell lesions (CCL) 262 CREST syndrome 135 chondrosarcoma 339 combined Creutzfeldt-Jakob disease (CJD) 11, metaplasia 240 blue naevus 287 22, 182, 378, 381, 383, 384–5 odontogenic tumours 129 corneal dystrophy of Fuch 196 Crohn’s disease 144–7 sarcoma 60, 323–4 germ cell tumours (testis) 224 cryoglobulinaemia 350 tumour (sugar, lung) 95 hepatocellular and crypt cell carcinoids 152 tumours of ovary 247 cholangiocarcinoma 172 Cryptococcus spp. 345, 14, 346, 364, tumours of salivary glands 132 hormone replacement therapy 253 100, 101, 307 clinical small cell carcinoma 93 cryptogenic fibrosing alveolitis (CFA) audit 29 subacute degeneration of the cord 84 governance 26, 378 183 cryptogenic organising pneumonia laboratories 23 vascular malformations 57 (COP) 85 CLL 110, 105, 107–10, 114, 124, 362, comedocarcinoma 259 cryptorchid testis 213 4, 47, 113, 167, 198, 304, 346, comedonecrosis 372 Cryptosporidia spp. 348, 351, 148 350 common variable immunodeficiency crystals and crystalloids clomiphene 254 (CVID) 142, 148, 351 alveolar soft part sarcoma 323 clonal naevus 288 communicable diseases 378 aspergilloma 370 Clostridium spp. 22, 143, 343 complete hydatidiform mole (CM) barium 148 CML 103–4, 123 63–4 BGC-associated 214 CNS 43, 181–8 complex sclerosis lesion (CSL) 262 calcium hydroxyapatite 375, 340 coal workers’ pneumoconiosis 85 composite thymoma 96 calcium pyrophosphate 375, 340 cocaine 89 conducting system 389–90 Charcot-B¨ottcher 211 cocci 343 congenital Charcot-Leyden 370, 103 coccobacilli 343 anomalies 56 cholesterol 184, 269, 360, 375 coeliac disease 142 cystic adenomatoid malformation cholesteryl esther 11 colitis 143–6 82–3 cholestyramine 148 amoebic 143 fibre type disproportion 191 cystine 365 Beh¸cet’s 145, 194 haemangioma 57 ice 43 bowel prep 148, 144 heart disease 78 joints / synovial fluid 375 chemotherapy 148 hepatic fibrosis 163 lipid 12, 303, 375 collagenous 146 myopathies 191 lysophospholipase 370 crescentic fold 146 naevus 288 Maltese cross 11, 12 Crohn’s 144–5 congophilic (amyloid) angiopathy oxalate 267, 273, 274, 365, 370 cystica profunda 146, 148–9, 151 (CAA) 72 PAMRAG 344 diversion 147 conjunctival PEComa (at EM) 326 diverticular disease-associated 146 melanocytic lesions 197–8 plasma cell 104 drug-induced 144, 148 198 polystyrene 148 focal active 146 myxoma 198 prostatic adenocarcinoma 220, 222, indeterminate 145 tumours 198 224 JWBK208-IND-II August 12, 2008 16:22 Char Count= 0

Index of General Terms 400

crystals (continued ) cytopathology 353–76 DFSP 325–6 Reinke 227, 249, 250, 251 cytophagic histiocytic panniculitis diabetes mellitus 61, 153, 178, 190, sclerema neonatorum 303 114, 302, 303 195–6 starch 11 diabetic steroid 375 D2-40 antibody 17 iridopathy 195 thyroid 267, 273, 274 DAD 84–5 mastopathy 263 urate 375, 340, 205, 207, 365 DALM 150–1 nephropathy 204 urine 365 danazol 253 retinopathy 195–6 CSF 364 data controllers 30 diagnostic immunohistochemistry cut-up 36–55 Data Protection Act 1998 (DPA) 26 8–9, 14–19 cutaneous Davies criteria 386 diagnostic slides (in the exam) 2 B-cell lymphoma 110 DCIS 52, 258–9, 260, 263–5, 373 diaphragm disease 142, 148 leishmaniasis 300 de Quervain’s thyroiditis 268, 367 DIC 207, 208, 382, 383, 385 mastocytosis 299 death certification 378–9 diethylstilboesterol 232 vascular lesions 57 decalcification 8 differentiated CVID 142, 148, 351 decornification 8 carcinoma of intermediate type cylindroma 292–3 decoy cells 365 (thyroid) 272 dedifferentiated teratoma 225–6 biliary 172 atypical lipoma 313 diffuse lung 91 chondrosarcoma 339 alveolar damage 84–5 ovary 244–6 chordoma 184 epithelioid granulomatous pancreas 177 liposarcoma 314 inflammation 351 salivary 134, 132 osteosarcoma 337 large B-cell lymphoma 105, 112, cystadenoma 134, 152, 177, 239, papillary thyroid carcinoma 270 113 244–6, 374–5 deep penetrating naevus (DPN) 290 Lewy body disease 181 cystectomies 49 degenerate urothelial cells 366 digital fibroma of infancy 57 cystic degenerative joint disease 340 dilated pore of Winer 292 dysplastic kidney 212 delta agent 160 dimorphic forms (of fungi) 345 endosalpingiosis 236 dementia 181–2, 381 DIP 84 fluid (breast) 371 demyelinations 182–3 direct maternal deaths 385 lesions (larynx) 82 denervation 190 discrimination 33–4 lesions (lung) 82–3, 91 dental cysts 128 diseases of the nipple 259–60 lesions (salivary) 133–4 dentigerous cysts 128 disposal of specimens 31–2 lesions (hepatobiliary) 172 deposits dissection 3, 36–55, 73, 388–90, 392 lymphoepithelial sialadenitis 133 in the heart 78 disseminated intravascular lymphoid hyperplasia 133–4, 364, in the skin 300 coagulation (DIC) 207, 208, 382, 369 dermal cylindroma 292–3 383, 385 medial necrosis 78 dermatitis herpetiformis 305 diversion proctocolitis 147 MESA 364, 369 dermatofibroma (DF) 326 diverticular disease-associated colitis mesenchymal hamartoma 83 dermatofibrosarcoma protruberans 146 mucoepidermoid carcinoma 134 (DFSP) 325–6 D¨oderlein bacilli 354 pancreatic tumours 177 dermatopathic lymphadenopathy doughnut granuloma 101 cysticercosis 350 120 DPAS 12 Cysticercus cellulosae 350 dermoid cysts drug-induced granuloma 101 cystinosis 207 ophthalmic 193–4 drugs and toxins cystitis 214–15 ovarian 251, 374 -methyldopa 160, 167 cystica calcinosa 349 testicular 225, 228 acetaminophen (see ‘paracetamol’) cystica glandulares 18, 364, 366 desmoid fibromatosis 57, 311 aflatoxin 168 cystoid degeneration of the retina intraosseous 334 alcohol (ethanol) 82, 137, 156, 157, 197 vs. fibrosarcoma 312 159, 160, 162, 164, 168, 175, cysts vs. GIST 141 183, 191, 380, 385, 387 breast 371 vs. non-ossifying fibroma 334 allopurinol 167 dental/jaws/facial 127–8 desmoplastic amiodarone 84, 157, 168 eye/eyelid 193–4, 197 fibroma 334 antibiotics 115, 142, 143, 148, 351, gynaecological 239, 243–4, 374–5 melanoma 290–1, 289, 327, 15, 48 382 see also specific types oesophageal 136 mesothelioma 90 antivirals 168 see also specific types osteoarticular 331, 333 small round cell tumour 58 aspirin / salicylates 84, 157, 167, peritoneal 153 Spitz naevus 289, 291 168, 334, 382  salivary gland 133–4 trichoepithelioma 293 Augmentin R 167 skin 282, 292, 295 desquamative interstitial pneumonia azathioprine 168, 169 thymic 57 (DIP) 84 bush tea 168, 169 urological 213, 228, 232 developmental calcineurin inhibitors 165, 206, 207, see also specific pathologies urological anomalies 212–13 208, 209 (CK) 14–15, 327 and see cardiac anomalies 386 carbon tetrachloride 168 Index of Molecules ophthalmic anomalies 193–5 carboplatin 226 cytology cases (for exams) 2 see also congenital cetuximab (anti-EGFR) 151 JWBK208-IND-II August 12, 2008 16:22 Char Count= 0

Index of General Terms 401

chemotherapy see dedicated entry tamoxifen 168, 238, 243, 254, 260, ear pathology 199–200, 388 in this index 261, 358 early invasive squamous carcinoma clomiphene 254 tetracyclins 81, 168, 329, 339 (cervix) 233–4  CMF 260 Thorotrast R 168, 173 EATL 115 cocaine / ‘crack’ 89, 168, 351, 385 TPN 142, 157, 164, 168 EBV see Epstein-Barr virus contraceptives (oral) 167, 235, 354 trastuzumab 260 ecchondroma 337 co-trimoxazole 168 valproate 168 eccrine poroma 292 cyclophosphamide 260, 365 vitamin A 168 eccrine spiradenoma 293 cyclosporin 165, 206, 207, 208, vitamin B12 142, 148, 183 Echinococcus spp. 350, 191 209 vitamin D 99, 329 eclampsia 61 danazol 253 vinyl chloride monomer 168 effectiveness 1  dapsone 298, 299, 305 Weedol R 89 effusions 360, 361–2 didanozine 168 weed killers 89 ejaculatory duct 220, 18, 42 diethylstilboesterol 232 zidovudine 167, 168 elastic  erythromycin 167 Zoladex R (goserelin) 242 arteries 68, 69 epratuzumab (anti-CD22) 107 Duchenne muscular dystrophy deposits 300 ferric sulphate 168 191 tissue 12 floxuridine 167 ductal embolism / emboli flucloxacillin 159, 167 adenocarcinoma (pancreatic) 176 air 390 fluorouracil 260 adenoma (breast) 264, 373 amniotic fluid 385 folic acid / folate 142, 148, 355 carcinoma (breast) 17, 260–1, athero 72 frusemide 168 371–2 cardiac 76  Glivec R (imatinib) 140 carcinoma in situ (breast) 52, chorionic (molar) 65 gonadorelins (GnRH) 254, 242 258–9, 260, 263–5, 373 lipid 69, 72, 202, 203, 207, 382, gonadotrophins 254 ectasia (breast) 260, 372 383  Grammoxone R 89 hyperplasia of usual type (breast) pulmonary 88, 73, 385, 386 halothane 167 258–9 talc 89, 88  Herceptin R 260 mucinous metaplasia (pancreatic) therapeutic 49 heroin / narcotics 83, 89, 169, 204 175 thrombo 74, 381, 382, 385, 390 HRT 253, 354 duodenum 126, 141–2 tumour 218, 271, 322 ibuprofen 167 dye nomenclature 8 (MTU) 226 iodine / iodides 267–8, 272, 368, dysgenetic disease (parotid) 134 embryonal rhabdomyosarcoma 58 194 52, 362, 252, 253 see emphysema 83 isoniazid 167 also employment regulations 23–6, 33–4 methotrexate 168, 102, 157, 376, dyshormonogenetic goitre 268 Encephalitozoon spp. 348 260 dyskaryosis 353, 355–7, 358 encephalopathy mineral oils 167 dysplasia acute haemorrhagic leuco 183, minocycline 167 acinar cell (pancreatic) 177 382 neuroleptics 181, 381 adenoma (colonic) 149–50 HIV 182 nifedipine 168 arrhythmogenic right ventricular 78 nephritic 201 nitrofurantoin 84, 167 arteriohepatic 164 Wernicke 385 NSAID 142, 148 see also specific associated with a lesion or mass (in encysted papillary carcinoma in situ types UC) 150–1 264 oestrogen 168, 238, 253, 264, 358 capillary alveolar 56 endocervical see also HRT and see cystic kidney 212 cells 354, 355, 356 oestrogenism ductal mucinous (pancreatic) 175 smears 353 paracetamol 159, 168 fibromuscular 73 endocervical-type borderline paraquat 89, 159, 167 fibrous 334 mucinous tumour (EBMT) 245  PathClear R 89 flat (colonic) 150 endochondroma 338 phenothiazines 167 see also flat (stomach) 138 endocrine neuroleptics gallbladder 174 pancreas 178–9 phosphorus 168 GIT glandular (general) 127 pathology 267–80 polystyrene sulphonate 144, 148 large cell (liver) 170 endodermal practolol 153, 311 liver cell 170–1 sinus 252 progestagens 92, 142, 167, 168, multicystic 212 tumour resembling fetal lung 92 242, 253, 358 neuroendocrine cell 139 endolymphatic sac papillary tumours rapamycin / TORi 210 non-polypoid 138 200 ribavirin 168 oesophageal glandular 135–6 endometrial rituximab (anti-CD20) 141,107 oesophageal squamous 136 cancers 51 soya oil 373 osteofibrous 334 carcinoma 240–1, 357 steroids (anabolic / androgenic) penile squamous 229 cells 354 167, 169 renal 212 hyperplasia 238 steroids (glucocorticoids) 168, 189, small cell (liver) 170 metaplasia 239–40 278 in squamous oral mucosa 129 polyps 238–9 tacrolimus (FK506) 165, 207, 208, dysplastic naevus 289 stromal tumours 242, 248 209 dysplastic nodules (liver) 170–1 tumours 246–7 JWBK208-IND-II August 12, 2008 16:22 Char Count= 0

Index of General Terms 402

endometrioid melanocytic naevus (Spitz/Reed) fasciitis adenocarcinoma (endometrium) 290 ‘burnt out’ 310 240–1 meningioma 186 cranial 311 adenocarcinoma (lung) 92 mesothelioma 90, 153, 17 eosinophilic 301, 303 adenocarcinoma (ovary) 246–7 neurofibroma 316 ischaemic 311, 310, 332 adenocarcinoma (prostate) 221, osteoblastoma (aggressive) 335 nodular 311, 310, 312, 108, 265, 222–3 osteosarcoma 337 270, 327, 373 cystadenoma 239 PEComa 326 ossificans 311 endometriosis 146–7, 239 sarcoma 324 proliferative 311, 310, 228, 332 endometriotic cysts 374 Schwannoma (malignant) 315 fat necrosis 372, 303, 372, 265, 266, endometrium 236–8, 254 smooth muscle tumours (uterine) 371, 373–4 post-ablation changes 240 241–2 female adnexal tumour of probable endosalpingiosis 254–5 soft tissue lesions 266 Wolffian origin (FATWO) 243 endothelial differentiation 317 epithelioma femur 390 Entamoeba coli 143 adenoid basal (cervical) 234 ferric iron 13 Entamoeba histolytica 143, 348 calcifying (of Malherbe) 293 fetal vascular anomalies (placenta) 62 Enterobius vermicularis 349, 346, 364 sebaceous 294 fibro-osseous lesions 129 enterocolitis, necrotising 56 Epstein-Barr virus (EBV) 347, 133, fibroblasts 310–12 Enterocytozoon spp. 348 120, 122 fibrolipoma 313 enteropathy type/associated T-cell lymphadenopathy 120 fibroelastoma, papillary 79 lymphoma (EATL/ETTL) 115 spleen 122 fibroma enzymic labelling 9 EQA 28 ameloblastic 128 eosin (haematoxylin and) 9–10 equal opportunities 33–4 bone 334 eosinophil granuloma 94, 120, 333 erosion (GIT) 126–7 cardiac 79 eosinophilia 107, 87, 103, 318 eruptive vellus hair cysts 295 chondromyxoid 338, 331–2 eosinophilia with maturation (bone erythema multiforme group 297 collagenous 310 marrow) 103 erythroblastosis fetalis 63 desmoplastic 334 eosinophilic erythroplasia of Queyrat 229 digital 57 cystitis 214 espundia 348–9 giant cell 129 effusions 360 essential thrombocythaemia 103 non-ossifying 334, 332 fasciitis 301 ETTL 115 nuchal-type 301 folliculitis 306 European grading (of DCIS) 259 oral 129 gastritis 137 European Working Time Directive ossifying 334, 129 oesophagitis 135 93/104/EC 1998 (EWTD) 22, 24 ovarian 250, 249 pneumonia 87 evisceration 3, 392 pleomorphic 326 sputum 370 Ewing’s sarcoma 58, 335–6, 337, 339, tendon sheath 311, 342 vasculitis 71 342, 361, 16, 108, 327, 330, 333 fibromatosis 311–12 ependymoma 188, 16, 17 exam candidates 1–5 breast 265, 373 vs. other lesions 139, 184–7, 279, exocrine pancreas 17, 46, 174–8 CD117 and 41 326 exogenous pigments 14 desmoplastic melanoma vs. 290 ephelis 287 external quality assurance (EQA) 28 GIST vs. 141 epidermal extra-renal rhabdoid tumour 324 infantile digital 286 cysts 282, 193, 295, 300, 317 extrahepatic juvenile hyaline 300, 326 lesions 282–5 bile ducts 164–5, 172 ovary (vs. fibroma) 250 epidermodysplasia verruciformis biliary artesia 164 paratesticular 228 (EV) 283 extramammary Paget’s disease 232 plexiform fibrohistiocytic tumour epidermoid cysts 228, 282 extramedullary haemopoiesis (EMH) and 312 epidermolysis 282 123 sclerosing angiosarcoma vs. 321 epidermolysis bullosa acquisita extranodal marginal zone lymphoma fibromuscular dysplasia / arterial (EBA) 305 (MZL) 111–12 hyperplasia 73 epididymal cysts 213 extraosseous osteosarcoma 337 fibrosarcoma 312 epididymis 212 extraprostatic extension of prostatic fibrosis epithelial carcinoma 222 bone marrow 100, 101, 102 cells (immuno) 17 extravasation mucocoele 134 liver 161 hyperplasia (breast) 258–9, 264, 372 extrinsic allergic alveolitis (EAA) fibrothecoma 250 repair (cervical cytology) 357 85 fibrous epithelioid eye pathology 37, 44, 193–9, 388 bodies 278 angiomyolipoma 216, 314 cortical defect 334 angiosarcoma 321 Fabry’s disease 206 dysplasia 334 dermatofibroma 326 Fallopian tubes 243 hamartoma of infancy 57 GIST 140–1 false positivity/negativity rates 32 papule of the face 286 granuloma 351, 363 familial ademomatous polyposis FIGO staging 233, 240, 244 haemangioendothelioma 95, (FAP) 138, 270, 272, 311 filamentous bacilli 343–4 321, 15 familial medullary thyroid carcinoma fine needle aspiration (FNA) artefacts haemangioma 318 279–80 265, 269 histiocyte / macrophage 363 FAP 138, 270, 272, 311 FISH 9, 260, 359 JWBK208-IND-II August 12, 2008 16:22 Char Count= 0

Index of General Terms 403

fixation 7–8 lymph nodes (benign inclusions) genital skin 288, 292 flat 118 germ cell tumours 224–6, 251–2, 362 adenoma (colon) 149–50 lymph nodes (inguinal) 39 germinoma 184, 224, 225, 17, 19 carcinoma in situ (urothelium) lymph nodes (sentinel) 118 gestational endometrium 236–7 219–20 lymphoma (Hodgkin) 117 giant cell dysplasia (GIT/gallbladder) 138, melanin (DOPA reaction) 14 arteritis 69–70 150, 174 mitotic counts in 7 astrocytoma 185 flexural naevus 288 Mohs’ surgery and 48 encephalitis 182 floppy mitral valve 76, 78 ovarian 253, 251 hepatitis 158 florid pancreatic carcinoma vs. accessory interstitial pneumonia 84 bile duct lesions (in PBC) 162 ducts 174 myocarditis 76 cystic endosalpingiosis 236 pancreatic carcinoma vs. chronic rich lesions 331–2 papillary mesothelial hyperplasia pancreatitis 175, 176 thyroiditis 268 255 pancreatic pseudocyst d/dg 175 tumour of bone / soft tissues 335 fluorophore in situ hybridisation parathyroid 274 tumour of tendon sheath 341–2 (FISH) 9, 260, 359 peritnoneal keratin granulomas 251 Giardia lamblia 347 fluorophores 8 peritnoneal leiomyomatosis 254 GIST 40–1, 126–152, 346, 361, 383 FNCLCC grading 327 pituitary 278–9 glandular FNH 169 renal tumours/cysts 218 dyskaryosis 356–7 focal reticulin in (by PAS) 11 dysplasia 127, 135–6 active colitis 146 signet ring cells 139, 214 metaplasia 355 chronic thyroiditis 268 testicular 228, 225 neoplasia 358 lymphocytic thyroiditis 268 thyroid 273, 267, 268 Gleason grading 222 nodular hyperplasia 169 see also per-operative cytology glial tissue 240, 251 segmental glomerulonephritis 203 FSGN 203 glioblastoma multiforme (GBM) 185 segmental glomerulosclerosis 204 FSGS 204 glioma 186, 187 follicular Fuch’s combined corneal dystrophy gliomatosis peritonei 254 adenoma 268–9 196 gliosis 187 carcinoma 269, 272 Fuhrman grading 218 glomerulonephritis (GN) 202–4 dendritic cell sarcoma 120 Fulton method 391–2 glomus tumours 285–6 hyperplasia 109 functional glottis 38–9 lymphoma 105, 111, 112, 124 cysts 374 GnRH 254 mucinosis 302 polyps 238 goblet cell carcinoids 152 (thyroid FNA) 367 fundic gland polyp 138 goitres 267, 268, 367 folliculolysis 119, 364 fungal infections 345–6 gonadoblastoma 252 formaldehyde fixation 7 gonadotrophin releasing hormone formalin pigment 13 galactose oxidase Schiff 12 (GnRH) analogues 254 foundation hospitals 33 gallbladder 172–4 Goodpasture’s disease 87–8, 70, 201, fracture callus 332–3 gangliocytic 202, 203 Francisella tularensis 119, 167 paraganglioma/hamartoma 179 GORD 134–5 Freedom of Information Act 2000 30 ganglioneuroblastoma 59, 316 gout 375–6, 365, 340, 207, 205, 329, frontotemporal dementias 181–2 ganglioneuroma 59, 316 300 frozen sections GANT 140 Government policy statements 33 autopsy 387 Gardnerella vaginalis 354, 343 gp100 15–16 biliary atresia (Kasai) 164 Gartner’s duct remnants 236 graft vs. host disease (GVHD) 148, breast 265–6 gastric 166, 306, 99, 142, 162, 167, 346 C4d staining in 209 adenoma 138 granuloma 351 carcinoma vs. gangliocytic carcinoids 140 annular elastolytic giant cell 300 paraganglioma 179 carcinoma 45–6, 138–9 annulare 299, 307 carcinoma vs. normal islets 178 glandular tumours (immuno of) 17 apical (periapical) 128, 127 carcinoma vs. somatostatinoma gastritis 137 barium 148 140 gastro-oesophageal reflux disease bone marrow 101, 103 carcinoma vs.malakoplakia 214 (GORD) 134–5 cholesterol 199, 201 central nervous system 187–8 gastrointestinal autonomic nerve contact (larynx) 82 cholangiocarcinoma d/dg 173 tumours (GANT) 140 CVID 351, 142 cholesterol emboli vs.GN202 gastrointestinal stromal tumours doughnut 101 CIBD 144, 145 (GIST) 140–1 drug-induced 101 exam advice 4 gastrointestinal tract (GIT) 40–1, D¨urck’s 348 fat/lipid in 12, 157, 202 126–152, 346, 361, 383 eosinophil 57–8, 94, 120, 333 H&E on 9–10 gastroparesis 153 epithelioid 363, 351 immuno and 9 Gastrospirillum spp. 343 epithelioid sarcoma vs. 324 inclusion body myositis 191 Gaucher’s disease 123, 99, 101, 196 faciale 299, 301 joint prosthesis revision 341 d/dg HX 58 fibrin ring 167 larynx 82 d/dg MAI 100 fungal 345 liver Tx (donor) 165 d/dg ITP 122 giant cell reparative 331, 334 lung 95 d/dg Whipples 142 Hodgkin lymphoma 117 JWBK208-IND-II August 12, 2008 16:22 Char Count= 0

Index of General Terms 404

granuloma (continued ) breast 265, 319, 320 hepatocellular adenoma (HCA) in colitis 143–5, 147, 148 cavernous 164 169–70 inguinale 343 cellular 318, 57, 321 (HCC) 46, keratin 251 chorionic 62 171–2 kidney 206 congenital 57 hepatocytes 156 lethal midline 115 epithelioid 318 HER2 over-expression 260 lipid 101, 194 glomus tumour vs. 286 HerceptestTMscore 260 liver 167, 159, 160, 162, 163, 166, hamartoma 62, 193 hereditary nephritis 205–6 170 histiocytoid 318 herpes gestationis 304 lymph node cytology 363, 364 hobnail 306 herpes simplex virus (HSV) 195, 304, MALTomas 91, 113 infantile 318, 57 357 metazoan 349 intramuscular 313, 319 HHV 347 mycobacterial 344 larynx 82 hibernoma 314 naked 298 microvenular (vs. KS) 322 hidradenoma papilliferum 293 neutrophils in 119 sclerosing 94, 326 hidroacanthoma simplex 292 palisaded 215 simplastic (vs. PHAT) 320 high grade plasma cell 310, 82 sinusoidal (vs. angiosarcoma) 320 dysplastic nodules 171 protozoal 348 spindle cell 318, 322 stromal sarcoma 242 pulmonary hyalinising 95 Spitz vs. 289 surface osteosarcoma 337 pyogenic 318, 319, 322, 57, 129 synovial 339 Hilar structures (of kidney) 41 ring 101 verrucous 285 Hirschprung’s disease (HD) 56 sarcoidal 87 haemangiopericytoma (HPC) 321–2 histiocytes (in cervical smears) 354 silicone 341 haemangiopericytoma-lke tumour histiocytic infiltrates 122, 340 skin 300, 298 322, 82 histiocytoid haemangioma 318 sperm 228 haematoxylin and eosin (H&E) 9–10 histiocytoid infiltrates 122 spleen 122, 124 haemazoin 13, 348 histiocytoses 286, 101 testis 215, 225 haemophagocytic syndrome 101 histiocytosis X (HX) 57–8, 94, 120, true cord 82 haemopoietic recovery 103 333 venerium 343 haemorrhagic histo-score (H-score) 260–1 granulomatosis 70, 86–7 cystitis 214 histological activity index (HAI) 160 granulomatous gastropathy 137 histological techniques 6–21 arthritis 340 pancreatitis 175 Histoplasma spp. 14, 345, 95, 100, cystitis 214 pulmonary syndromes 87–8 101, 215, 307, 346, 347, 349, 383 endometritis 239 HAI 160 HIV see human immunodeficiency gastritis 137 Hailey-Hailey disease 304 virus inflammation 351 hair 295 hives 299 myocarditis 76 hairy cell leukaemia (HCL) 105, HMB45 15–16 orchitis 215 123 hobnail prostatitis 215 Hale’s colloidal iron 12, 217 cells 247, 249, 264, 91–2, 217, 219, pyelitis 214 halo naevus 288 235, 237 splenitis 122 hamartia 193 cell metaplasia 240 thyroiditides 268 hamartoma 57, 62, 83, 169,171–2, haemangioma 306 uveitis 195 179, 193, 333 HOCM 78 see also granuloma hard tissues 8 Hodgkin lymphoma (HL) 105, granulosa cell tumour 249, 374 Hart-Norris classification 245 116–18, 362, 363 Graves’ disease 267, 367 Hashimoto’s thyroiditis 267–8, 367 honeycomb Group A Streptococcus-associated hazard groups (HG) 22, 23 bubbly alveolar casts 370 diseases 344 HCL 105, 123 lung 84 GVHD 148, 166, 306, 99, 142, 162, Health & Safety 22–3 hordeolum 194 167, 346 Health of the Nation, The 33 horizontal growth phase (HGP) gynaecological pathology 232–57 Health and Safety at Work Act 1974 melanoma 291 gynaecomastia 264 (HSWA) 22 hormone replacement therapy (HRT) gynandroblastoma 249 heart 75–80 253 autopsy 383, 389–90 HPV 233–4, 354–5, 283, 359, 346 H-score 260–1 conducting system 39, 389 HRT 253, 354 haemangioblastoma 187, 17, 177, transplants 77–8, 386 HSV 195, 304, 357 185, 186 see also cardiac HTLV-1 107, 115–16, 350 haemangioendothelioma Helicobacter pylori 14, 112, 135, 137, human herpes virus (HHV4/8) related epithelioid 321, 95, 327, 15, 165, 141, 343 disease 347 173 hepatitis 158–61, 166, 167, 384 human immunodeficiency virus (HIV) infantile 57, 321 hepatitis A virus (HAV) 158 autopsy 384 Kaposiform 322, 321, 57 hepatitis B virus (HBV) 159–60 bone marrow 100 reteform 306 hepatitis C virus (HCV) 160, 384 cholangiopathy 165 spindle cell 318 hepatitis D virus (HDV) 160 cystic lymphoid hyperplasia 133–4 haemangioma hepatitis E virus (HEV) 158 cytopathology 363–4 atypical (breast) 320 hepatoblastoma 59 encephalopathy 182 JWBK208-IND-II August 12, 2008 16:22 Char Count= 0

Index of General Terms 405

lymphadenopathy 119, 363 retroperitoneal fibrosis 311 intermediate cells (cervical smear) nephropathy 204 sclerosing mediastinitis 311 353 skin 306–7 sclerosing peritonitis 311 interstitial spleen 122 thrombocytopenic purpura 103, 122 cystitis 214 viral infections 346–7 ileal conduit urine 366 lung disease 83–5 see also acquired immunodeficiency ileal reservoirs 147 nephritis 206–7 syndrome immature teratoma 251–2 intervillous thrombus 62 human papilloma virus (HPV) 233–4, immunoblastic reaction 115 intestinal 354–5, 283, 359, 346 immunocytochemistry 8–9, 13, lymphoma 112–13 human T-cell lymphotrophic virus 1 14–18, 100, 107–9, 224, 258, metaplasia 137, 135–6, 14, 138, 172 (HTLV-1) 107, 115–16, 350 291, 310 intestinal-type borderline mucinous Human Tissue Act 2004 26, 377–9 immunodeficiency 306–7 tumour (IBMT) 245 humoural rejection 77, 209 immunological diseases/disorders intimal sarcoma 322 Hunner’s ulcer 214 86–7, 350–1 intraduct papilloma 264 Huntingdon’s disease 182 in situ hybridisation (ISH) 9, 260, 233, intraductal papillary mucinous H¨urthle cell 277, 172, 359, 7, 93 (IPMN) 176 lesions 367 incomplete septal cirrhosis 169 intramuscular tumours 269, 270 incontinentia pigmenti 297 haemangioma 319 hyaline indeterminate colitis (IC) 145 lipoma 313 arteriosclerosis 68 indirect maternal deaths 385 intranodal haemorrhagic spindle cell cartilage 329 infantile tumour with amianthoid fibres membrane disease 56, 383 digital fibromatosis 286 312 hyalinising trabecular adenoma (HTA) fibromatosis 57 intranuclear cytoplasmic inclusions 271 fibrosarcoma 57 367 hyalinising trabecular tumour (HTT) 271 haemangioma 57, 318 intrathyroidal thymic carcinoma hyalinoses 300 naevus 288 273 hyatid disease 350 respiratory distress syndrome 56 intratubular germ cell neoplasia hydropic abortion (HA) 65 infarcts unclassified (ITGCNU) 224–5 hydrops fetalis 63 myocardial 75–6 intra-uterine contraceptive devices hyperacute rejection 165, 208, 350 placental 61 (IUCD) 239, 357 hypercalcaemic small cell carcinoma infections 166–7, 307, 343–50, 364 intra-uterine death (IUD) 62, 63 248 infectious mononucleosis 120, 122, invasive hyperparathyroidism 329–30 167, 347 hydatidiform mole 65 hyperplasia infective colitis 143 thymoma 96 of gynaecomastoid type 264 infertility 212, 237, 244 inverted of usual type (HUT) 258–9, 372 infiltrates follicular keratosis 283 see also specific pathologies cardiac78 papilloma 219 hyperplastic haematolymphoid 101–2, 105 iron 13, 99, 156 clusters of respiratory epithelial histiocytic/oid 122 ischaemia cells 370 infiltrating lobular carcinoma (ILC) brain 182 polyp 138 261 chorionic villi 61 reserve cells 354 inflammatory colon 146 hypersensitivity 350 arthropathies 340–1 liver 168 hypertension bowel disease 56, 113, 143–7, ischaemic maternal 61 150–1 fasciitis 311 portal 168 cervical smear changes 355 heart disease 75–6 pulmonary 69, 88 cloacogenic polyp 149 hypoxic brain injury 182 renal presentation 201 conditions 193–5, 213–15, 239, isolated tumour cells (ITC) 43 retinopathy 195 296–302, 364 isosporiasis 348 systemic 68–9 fibroid polyp 138 ISSVA classification 57 hypertrophic obstructive heart disease 76–8 isthmic endometrium 236, 357 cardiomyopathy (HOCM) 78 myofibroblastic tumours 57, 310 ITGCNU 224–5 hyphal forms (of fungi) 345 myoglandular polyp 149 ITP 103, 122 hypocellular smears 373–4 nasal polyps 81 IUCD 239, 357 hypokalaemia 206 polyp 149 IUD 62, 63 hypopharynx 38 pseudotumour 310 hysterectomy 42–3, 51 inguinal lymphadenectomy 39 Johnsen’s score 212 inner ear 388 joint prosthesis pathology 341 idiopathic inquests 380 joints 339–42 adulthood ductopaenia 162 insular carcinoma 272 junior doctors 23–4, 25–6 calcinosis cutis 300 interdigitating dendritic cells 109, juvenile chronic hepatitis 166 120–1 granulosa cell tumour 249 giant cell myocarditis 76 interface activity (liver) 159 papillomatosis 263 myelofibrosis 102 interface dermatitis 297 polyp 149 nodular glomerulosclerosis 204 interfollicular Hodgkin lymphoma rheumatoid arthritis 194 pulmonary haemosiderosis 87 118 xanthogranuloma 325 JWBK208-IND-II August 12, 2008 16:22 Char Count= 0

Index of General Terms 406

juxta-articular myxoma 327 Leishmania spp. 348–9, 100, 101, low grade juxta-articular osteoporosis 330 109, 122, 135, 167, 300, 343, dysplastic nodules 170–1 juxta-cortical osteosarcoma 337, 336 345, 347 fibromyxoid sarcoma 312 juxtaglomerular apparatus leishmaniasis (cutaneous) 300 lower uterine segment endometrium hyperplasia 210 Lendrum’s phloxine tartrazine alcian 357 green 10 Luce Report 378 Kala-azar 348–9 lentigo luetic aneurysms 72 Kaposi sarcoma (KS) 322–3, 364, 4, maligna 289 lung 47–8, 56, 82–95, 361 16, 119, 320 senilis (actinic) 288–9 lymphoid lesions 90–1 Kaposi Sarcoma-related herpes virus simplex 288 septa 56, 319 (KSHV) 347 LESA 132–4 transplant pathology 84, 386 Kaposiform haemangioendothelioma leukaemia 103–5, 115–16, 123, 362 lupus pernio 300 322, 321 leukaemic infiltrates (bone marrow) luteal phase defect (LPD) 237–8 Kawasaki’s disease 72, 119 105 lymph nodes 43, 107–21, 319, 327, keratitis 195 leukocytoclastic vasculitis (LCV) 71, 363–4 keratoconus 196 301 lymphadenopathies 119, 120, 363 keratocystoma 134 Leydig (LAM) keratosis 282–3 cells 211, 15, 213, 243, 251 92–3 Ki-67 proliferation labelling index 7 tumours 227, 249, 52, 245, 246, lymphatics 70, 320 kidney see renal 250, 251 lymphocyte depleted Hodgkin Kikuchi-Fujimoto disease 119 lichen lymphoma (LDHL) 118 Kimura’s disease 318 amyloidosus 300 lymphocyte predominant Hodgkin Klebsiella rhinoscleromatis 81 aureus 301 lymphoma (LPHL) 117 knowledge 1 myxoedematosus 301 lymphocyte predominant patchy K¨ohler illumination 6 nitidus 298, 297 deep/mid dermal infiltrates kraukosis vulvae 232 planopilaris 298, 295 297 Krukenberg tumours 249 planus 298, 129, 130, 160, 297, 303, lymphocyte-rich classical Hodgkin KSHV 347 306, 307 lymphoma (LRCHL) 117 Kupffer cells 156, 167, 170 planus pemphigoides 298, 304 lymphocytic K¨uttner’s tumour 133, 311 planus-like keratosis 298 colitis 146 sclerosus 215, 301 gastritis 137 labelling (for immuno) 8–9 simplex chronicus 296, 300 lobulitis 263 Labelling, Transport and Reception of striatus 296 thyroiditides 267 Specimens Regulations (1985) light chain nephropathy 205 vasculitis 71, 301 23 ligneous thyroiditis 268 lymphoepithelial lesions (LEL) 111 laboratory management 22–35 limited autopsies 386–7 lymphoepithelial sialadenitis (LESA) lactation 372, 264, 265, 266, 277, linear IgA disease 305 132–4 358, 371 lipid lymphoma 109–18, 123–4 lactational nodule (‘adenoma’) 264 cell tumour NOS 250 alimentary tract 141, 143, 149 LAM 92–3 granuloma 101, 194 central nervous system 187 Lambl’s excrescence histological techniques 12 cytopathology 362–3 usual type 75 lipoblastoma 314 endocrine 273 giant (papillary fibroelastoma) 79 lipofuscin 13 see also specific pathologies lamellar bone 329 lipoid nephrosis 204 lymphomatoid papulosis (LyP) 299, Langerhans cell histiocytosis 57–8, lipoma 276, 313–14 302 94 lipopeliosis 165 lymphomatous infiltrates (bone large cell liposarcoma 314–15 marrow) 105 acanthoma 283 liquid-based cytology (LBC) 358–9 lymphoplasmacytic lymphoma (LPL) carcinoma 92 Listeria spp. 167, 63, 343 105 dysplasia 170 liver 156–73 lymphoplasmacytic sclerosing lymphoma 105, 109, 116 autopsy 383, 385 pancreatitis 175 larva migrans 349 cell dysplasia 170–1 lymphoproliferative conditions laryngeal nodules 82 cut-up/reporting 46 296–302 laryngectomy 45 porta hepatis (contents of) 40 lymphoreticular pathology 107–25 laryngopharynx 38 segmental anatomy of 41 LyP 299, 302 larynx 38–9, 82 transplant pathology 165–6 Laur´en’s classification 138 lobular macro resections 44–54 LBC 358–9 activity (liver) 159 macro-regenerative nodules (MRN) LCIS 262, 259, 263 breast carcinoma 17, 261, 372 171 left ventricular hypertrophy (LVH) carcinoma in situ 262, 259, 263 macroscopic pathology (exams) 2 391–2 hyperplasia 236, 262 macrovesicular steatosis 157, 168 Legionella spp. 14, 343 neoplasia 262, 261 malabsorption 141 legislation 22, 30, 31, 377, 379–81 panniculitis 303 malakoplakia 214 leiomyomatosis 242 regions and zones (liver) 156 malaria 348 leiomyomatosis peritonei 254 localised fibrous tumour 94, 324 malarial pigment 13 241–2, 309 long cases (exam) 2 maldescended testis 213 JWBK208-IND-II August 12, 2008 16:22 Char Count= 0

Index of General Terms 407

malignant thymoma 96 to skin 282, 293, 294 breast cytology 371–2, 373 thyroid carcinoma 271–2, 273, to stomach 139 fibrous histocytoma 325 279–80, 368 to testis 228 hypertension 69 medulloblastoma 59, 188 to thyroid 272, 273 melanoma 48, 290–1, 118, 362–3, megaloblastic anaemia 100 to thyroid 368 323–4, 277 melan-A 16, 249, 276, 290–1 metastatic meningioma 186 melanin 13–14 abscess 83 mixed germ cell tumour 252 melanoacanthoma 283 chondroblastoma 338 mixed M¨ullerian tumour 240, 243, melanocytic endometriosis 239 252 lesions 197–8, 286–91 giant cell tumour of bone / soft mixed tumour 294 naevi 197–8, 287–90 tissues 335 otitis externa 199 melanoma 48, 290–1, 118, 362–3, hydatidiform mole 65 paratesticular tumours 228–9 323–4, 277 leiomyoma (benign) 242 peripheral nerve sheath tumour 316 melanosis pleomorphic adenoma 130 pilomatrixoma 294 coli 147 sarcoma (to LN) 327 renal tumours 216–18 oculi 197–8 testicular tumours 228, 51 Schwannoma 315 membranes 63 metazoan infection 349–50 syringoma 293 membranoproliferative methotrexate 168 teratoma 225–6 glomerulonephritis (MPGN) 203 MGUS 105 teratoma trophoblastic 226 membranous glomerulonephritis 203 microbiopsies (CIN3) 356, 358, 359 Mallory hyaline 156–7, 159–60, MEN 279–80 microcalcifications (breast) 259, 265 162–4, 169–72 M´en´etrier’s disease 137 microcarcinoids 139 MALT lymphoma 91, 111–13, 141, meningeal tumours 186–7 microcystic 142 meningioma 186, 187 adenoma (pancreas) 177 mammary duct fistula 260 meningothelioid nodules 94 adnexal carcinoma 293 Management for Doctors 33 menstrual endometrium 237 microglandular adenosis (MGA) 262 Management of Health and Safety at Merkel cell carcinoma 294 microglandular endocervical Work Regulations 1999 MESA 132–3 hyperplasia (MGH) 235, 357 (MHSWR) 22 mesangiocapillary micropapillary mandible 45 glomerulonephritis 203 breast carcinoma 264 mantle cell lymphoma (MCL) 113, mesangioproliferative serous carcinoma 244 124, 149 glomerulonephritis 203 transitional cell carcinoma 219 marble bone disease of mesenchymal microscopic Albers-Sch¨onberg 330 chondrosarcoma 339 colitis 146 marginal zone lymphoma (MZL) 105, hamartoma 83, 171, 333 polyarteritis 69–70 111–12, 124 mesothelial cells 360, 89–90 microsporidiosis 348 Martius scarlet blue (MSB) 10 mesothelioma 89–90 microvesicular steatosis 157, 168 massive necrosis (liver) 158 features in pleural fluid 359–60 middle ear 200, 388 massive perivillous fibrin deposition metabolic mineralisation (of bone) 329 (MPVFD) 62 disorders and the skin 300 Ming’s classification 138 Masson’s myopathies 190 minimal change disease 204 bodies 84–5, 89 studies 387 minimal deviation adenocarcinoma trichrome 10 metanephric adenoma 216 (MDA) 235 mast cell metaphyseal fibrous defect 334 minute pulmonary chemodectoma 94 histotechniques 18 metaplasia(s) mitoses in benign melanocytic lesions immunocytochemistry 100 cytopathology 354–5, 357 287 infiltrates 101–2 endometrial 239–40 mitotic counts 7 tryptase 382 gynaecological 235–6, 239–40 mixed mastocytosis 102, 122 mucinous 175, 240 cellularity (Hodgkin’s) 117 maternal nephrogenic 218–9 dementias 181 antiphospholipid antibody squamous 63, 148, 239, 354, 355 hamartoma of childhood 169 syndrome 61–2 urological 218 lobular/septal panniculitis 303 death 385 metastases medullary carcinoma 272 diabetes 61 to adrenal 277 M¨ullerian neoplasia 242–3 hypertension 61 to bladder 220 M¨ullerian tumours of the ovary 248 maxilla 45 to bone 332, 335, 129 tumour of the skin 294 MDT 29–30 to brain 187, 188 types of breast carcinoma 261 MEA 279–80 to breast 264, 373 MMMT 240, 243, 252 meconium staining 13, 63 to heart 79 mnemonics list 4 mediastinal pathology 95–7 to kidney 218 modernisation of pathology 28 Medical Workforce Planning in to liver 46, 172, 173 Modernising Medical Careers 25–6 Histopathology 25 to oesophagus 136 modified histological activity index medullary to ovary 248–9, 246, 247, 253 (HAI) 160 carcinoma of the breast 261 to pituitary 278 Mohs’ micrographic surgery 48 osteosarcoma 336–7 to salivary gland 132, 134 molluscum contagiosum 346, 283, sponge kidney 213 to serous cavities 361–2 307 JWBK208-IND-II August 12, 2008 16:22 Char Count= 0

Index of General Terms 408

monoclonal gammopathy of encephalitis 182 infantile 288 undetermined significance rich lesions 331–2 melanocytic 197–8, 287–90 (MGUS) 105 multiple endocrine adenopathy neonatal 288 monophasic blastoma 92 (MEA) 279–80 neurotised 288 morbidly adherent placentae 65 multiple endocrine neoplasia (MEN) ocular 197–8 morphoea 301 279–80 of Becker 287 Morton’s neuroma 317 multiple peripheral papilloma (breast) of Ito 287 mouth 127–30 263 of Jadassohn 284 Movat’s pentachrome 10 multiple sclerosis (MS) 182–3 of Ota 197, 287 MRSA 22 muscle see skeletal muscle and of Reed 290, 286 MSB 10 smooth muscle of Spitz 289–90, 286 MTT 226 muscular of Sutton 288 MTU 226 arteries 68, 69 organoid 284 Mucha-Habermann disease 298 dystrophies 191 recurrent 286, 287 mucicarmine 12 mycobacterial pseudotumour 344 sebaceus 284 mucin-containing tumours 273 Mycobacterium spp. 344, 14 traumatised 287, 286 mucinous mycoplasma-associated diseases 344 vascular 281 carcinoids 140, 152, 252–3 myelins 13 white sponge 133 carcinoma (breast) 373, 260, 261, myelodysplasia (MDS) 102, 123 narcotics 89, 83, 169, 204 13, 264, 372 myelofibrosis 102, 123 nasal polyps 81 carcinoma (colon) 151 myelolipoma 276 NASH 157–8, 168 carcinoma (endometrium) 241 myeloma 104–5, 109 nasopharyngeal carcinoma (NPC) 81 carcinoma (prostate) 223 myeloma kidney 205 nasopharynx 38 carcinoma (skin) 264, 13 myocardial infarction (MI) 75–6 National Framework for Pathology carcinoma (stomach) 138, 139 myocarditis 76 Service Improvement 28 carcinoma (thyroid) 273 myoepithelial National Service Frameworks (NSFs) cyst (vulva) 232 carcinoma 130 33 cysts and tumours (hepatobiliary) cells 18 National Spine 33 172, 366 sialadenitis 132–3 National Tariffs 27–8 metaplasia (gynae) 240 myoepithelioma of salivary gland 130 natural killer (NK) lymphoma 114–16 metaplasia (pancreatic) 175 myofibroblastoma 312 NCI grading 327 tubular spindle cell carcinoma myofibroblasts 57, 310–12 neck 37, 44–5 (kidney) 216 myofibromatous lesions 285 necrobiosis lipoidica 298 tumours (appendix) 152, 254 myoinvasion 241 necrobiotic conditions 298 tumours (lung) 91–2, 369 myopathy 153, 190–1, 389 necrotising tumours (ovary) 245, 247, 375, 248, nemaline rod 191 enterocolitis 56 249, 251, 254 polyglucosan inclusion 153 external otitis 199 tumours (pancreas) 176, 177 myositis histiocytic lymphadenitis 119 mucins 12–13, 126 ossificans 309, 333 sarcoid angiitis 86–7 mucocoele proliferative 311 sarcoid granulomatosis 86–7 appendix 152 myospherulosis 81 sarcoidosis 86–7 extravasation 134 myotonic dystrophy 191 sialometaplasia 133 -like lesions of the breast 265, 13 myrmecia wart 283 negative predictive value 32 retention 134 myxoedema 268 nemaline rod myopathy 191 mucocutaneous Leishmaniasis myxofibrosarcoma 312 neonatal 348–9 myxoid hepatitis 158 mucoepidermoid carcinoma (MEC) leiomyosarcoma 242 large bile duct obstruction 164 92, 132, 134, 273, 368 lesions 326–7 lung disease 56 mucormycotic zygomycosis 345–6 liposarcoma 314 naevus 288 mucosa-associated lymphoid tissue myxoma 78, 198, 326–7 neoterminal ileitis 143 (MALT) 91, 111–13, 142 nephritic factor 203 mucosal naevoid melanoma 291 nephritic syndrome 201 neuroma 317 naevus nephritis prolapse syndrome 149 acral 288 hereditary 205–6 retention cysts 369 basal cell (syndrome) 128 interstitial 206–7 multicystic blue 287, 197, 316 nephroblastoma 59–60 dysplasia (kidney) 212 blue rubber bleb 281 nephrocalcinosis 205, 207 mesothelial proliferation 153 cells in lymph nodes 118 nephrogenic adenoma (NA) 218, 219 multidisciplinary bereavement teams clonal 288, 287 nephrogenic metaplasia 218, 219 (MDBT) 377–8 congenital, atypical nodule in 288 nephropathy 204, 206–7, 213 multidisciplinary teams (MDT) deep penetrating 290 nephrotic syndrome 201 29–30 dysplastic 289, 287, 288 neural soft tissue tumours 315–17 multinodular goitre (MNG) 267, 367 epidermal 282, 284 neuroblastoma (NB) 59, 185, 316 multinodular oncocytic hyperplasia flexural 288 neuroendocrine (MNOH) 131 genital 288 cell distribution in the colon 126 multinucleated giant cell halo 288 cell dysplasia 139 JWBK208-IND-II August 12, 2008 16:22 Char Count= 0

Index of General Terms 409

cell hyperplasia 139 oesophagitis 134–5 Pagetoid reticulosis 302 neoplasia of the liver 174 oesophagus 126, 134–6, 361 Paget’s disease pathology of the GIT 139–40 rupture of 361 of bone 330 proliferations of the lung 93 oestrogenism 227, 243, 244, 249, 250, extramammary 232 neurofibroma (NF) 316 251, 264, 358 of the nipple 259 neurofibromatosis 316 olfactory neuroblastoma 184 painful neurogenic myopathies 190 oligoastrocytoma 186 bladder syndrome 214 neurothekeoma 316, 318 oligodendroglioma 186 lumps in the skin/subcutis 281 neurotropic melanoma 290–1 Ollier’s disease 338 painless haematuria 201 never forget group 4 OMEE 236 pale dyskaryosis 356 New Consultants’ Contract 24 oncocytoma 131, 278, 368 palisaded myofibroblastoma 312 New Contract for Junior Doctors 23–4 oncocytosis 131 palms of hands 281 New Deal for Doctors in Training 23–4 oncofetal protein M2A 17 pan-acinar necrosis 158 NF 316 opportunistic infections 307, 346, pan-lobular necrosis 158 NF-1 associated vasculopathy 73 363–4 PanIN 175 NHS Cancer Plan 30, 33 oral pancreas 174–9 NHS Confederation 33 dysplasia 129 autopsy 383 NHS Plan 33 fibrous polyps 129 divisum 174 NHSBSP reporting categories 265, hairy leukoplakia 133 endocrine 178–9 358, 371 SCC 130 exocrine 17, 46, 174–8 nipple 259–60 orbital tissues, tumours of 199 glandular tumours 17 NK see natural killer orcein 12 hyperplasia 175 NLPHL 117 organising pneumonia (OP) 85 pseudocyst of 175 Nocardia spp. 14, 343 organoid naevus 284 transplant pathology 179 nodular oropharynx 38, 127–30 pancreatitis 175 fasciitis 311, 310, 312, 108, 265, ossifying fibroma 334 pancreatoblastoma 59 270, 327, 373 osteitis deformans 330 panniculitis 302–3 lymphocyte predominant Hodgkin osteoarthritis 340 ossificans 309 lymphoma 117 osteoarticular pathology 329–42 pannus adiposus 302–3 paragranuloma 117 osteoblastoma family of lesions 335 Papanicolaou 353 prurigo 296, 282 osteoblastoma-like osteosarcoma 335 papillary rectovaginal endometriosis 239 osteocartilagenous exostosis 337 carcinoma in situ (breast) 264 regenerative hyperplasia 169 osteochondroma 337 cystadenocarcinoma (salivary) 134 sclerosis Hodgkin lymphoma 117 osteodystrophy 330 cystadenoma (salivary) 134 non-alcoholic steatohepatitis (NASH) osteofibrous dysplasia 334 endocervicitis 236 157–8, 168 osteogenesis imperfecta 331 fibroelastoma 79 non-cohesive tumours 361 osteoid 11, 332, 334 inner ear tumours 200 non-gonadal teratoma 59 osteoma 334 mesothelial hyperplasia 255 non-molar hydropic abortion (HA) 65 osteomalacia 329 mesothelioma 153 non-ossifying fibroma 334 osteomyelitis 330 mucinous neoplasms (pancreatic) non-specific osteonecrosis 330 176 colitis 146 osteopetrosis 330 necrosis (renal) 206 interstitial pneumonia 84 osteoporosis 330 renal cell carcinoma 217 lung changes 83 circumscripta 330 serous carcinoma 90, 153, 244 non-steroidal anti-inflammatory osteosarcoma 336–7 syncytial metaplasia 240 drugs (NSAIDs) 142, 148 osteotis fibrosa cystica (OFC) 329–30 thyroid carcinoma 269–71, 272, Nottingham Prognostic Index (NPI) otosclerosis 199 273, 367–8 260 ovaries 243–53 papova virus 365, 209, 183 NSAIDs 142, 148 see also drugs and carcinoid 252–3 papular mucinosis 301 toxins cut-up/reporting 51–2 parabasal cells 353 NSIP 84 cysts / cystic tumours 243–7, 374–5 paradental cysts 128 nucleic acids 13 cytopathology 361 paraganglioma 279 nucleoli in cervical smears 355–6 endometriotic cysts 239 paragangloid tumour (PLAT) 271 NWTS staging 60 grading surface epithelial paraprotein (M-protein) 104, 205 carcinoma 248 paraprotein-associated obliterative bronchiolitis 85–6 lymphoma 253 xanthogranuloma with obstructive colitis 146 metastases to 248–9 necrobiosis 299 odontogenic serous carcinoma 244, 90, 153 parapsoriasis 302 cysts 127–8 overlap syndromes 161 paraquat 89 keratocysts 128 oxyphil metaplasia of the endocervical paratesticular tumours 228–9 tumours 129 epithelium (OMEE) 236 parathyroid 274–5 oesophageal oxyuriasis 349 adenoma 274 carcinoma 136 carcinoma 274–5 dysplasia 135–6 paediatric pathology 56–60 hormone levels 274 nodules/cysts 136 Pagetoid urothelial CIS 219 hyperplasia 274 tumours (cut-up/reporting) 45 Pagetoid melaoncytosis 286–7 tumours (cut-up/reporting) 53 JWBK208-IND-II August 12, 2008 16:22 Char Count= 0

Index of General Terms 410

paraxial demyelination 183 pigments 13–14, 339 polyposis Parkinson’s disease 182 pilar sheath acanthoma 292 familial adenomatous 272 parosteal osteosarcoma 337 pilocytic astrocytoma 185 serrated adenomatous 150 partial hydatidiform mole 64–5 pilomatrix carcinoma 294 lymphomatous 149 particulate matter 375 pilomatrixoma 293–4 polyp Parvovirus B19 related disease 347 PIN 221 adenomatous colonic 149–50 PAS 12 pineal tumours 184 adenomatous gastric 138 pathology pinguecula 196 adenomatous prostatic 220 modernisation 28, 27 pinworm 349 aural 199, 319 reports 30–1 pituitary cancer (colon) 151, 150 pattern matching 1 adenoma 277–8 cancer (uterine) 239, 238 Payment by Results (PbR) 27–8 carcinoma 277–8 cap 149 PBC 162–3 pathology 277–9, 383 endometrial 238–9 PCOS 244 pityriasis lichenoides chronica (PLC) fibrous oral 129 PEComa 326, 16 298 fundic gland 138 peliosis pityriasis lichenoides et gallblader 174 bacillary 167 varioliformis acuta (PLEVA) 298 hyperplastic colonic 150, 152 hepatis 167, 168, 169, 170 placenta 52, 60–6 hyperplastic gastric 138 insulis 178 placental mesenchymal dysplasia 65 inflammatory 81, 138, 149 lipo 165 placental site trophoblastic tumour inflammatory cloacogenic 149 splenic 123 (PSTT) 66 inflammatory fibroid 138, 141 pelvic peritoneal endometriosis 239 plasma cell inflammatory myoglandular 149 pemphigoid 304 granuloma 310, 82 juvenile 149 gestationis 304 immunocytochemistry 100 metaplastic colonic 150, 152 pemphigus 303–4 myeloma 104 oesophageal 136 penile plasmacytosis 104 Peutz-Jaghers 149 amputation 51 Plasmodium spp. 348 serrated colonic 150, 152 anatomy 42 platelet sequestration disorders 122 tamoxifen 238, 243 lesions 215 pleomorphic vaginal 232–3 neoplasia 229 carcinoma (lung) 92 pork tapeworm 350 per-operative cytology hyalinising angiectatic tumour 315, poroma 292 thyroid 273 320 porphyria 305, 156 osteosarcoma 336 lipoma 313 portal pituitary 278 liposarcoma 314 hypertension 168 see also frozen section rhabdomyosarcoma 58 hypertensive gastropathy 137 peribiliary gland hamartoma 172 salivary adenoma 130, 368 inflammation 159 perinatal autopsy 392–3 pleural vein thrombosis 168 periodic acid Schiff (PAS) 12 fluid 359–60, 391 positive predictive value 32 periosteal tumours 89–90 post-capillary venules (PCVs) 68, 70 chondroma 338 pleuropulmonary blastoma 90 post-colectomy ileitis 143 osteosarcoma 337 PLEVA 298 Postgraduate Medical Education and peripheral plexiform Training Board (PMETB) 26 blood 107 ameloblastoma 128 post-infective ADP GN 202 nerve biopsies 389 fibrohistiocytic tumour 312, 318 postmenopausal cervical smears 354 neuroectodermal tumour 58, 316 layers of the retina 193, 195, 197 postmortem 23, 377–393 periportal necrosis 158 lesion (of pulmonary HT) 88 endoscopy 386 periprosthetic soft tissue membrane 341 neurofibroma 316 frozen section 387 peritoneum 90, 153, 254–5 Schwannoma 315 genetic studies 387 perivascular epithelioid cell tumour spindle cell naevus 290 haematology 387, 383 (PEComa) 326, 16 tumourlet 242 health and safety 23 perivenous encephalomyelitis 183 PMETB 26 imaging 387 Perls’ Prussian blue reaction 13 PNET 58, 316 laparoscopy 386 pernio 300 pneumoconioses 48, 85–6 macro staining (histochemistry) 387 Peutz-Jeghers polyp 149 Pneumocystis spp. 14, 347, 370 microbiology 387 PGL 364 pneumonia 84–5, 87 molecular studies 387 phaeochromocytoma 276 polyarteritis nodosa (PAN) 69, 70 needle biopsies 386 pharynx 38–9 polychondritis, relapsing 86 prosthetics 386, 388, 389 PHAT 315, 320 polycystic special dissections 388–92 phosphotungstic acid haematoxylin disease of the parotid 134 toxicology 387 (PTAH) 10 kidney disease 212–13 weights and measures 391–2 phyllodes tumours 262–3 ovarian syndrome 244 see also autopsy Pick’s adenoma 227 polycythaemia rubra vera (PRV) post-operative spindle cell nodule pigmented spindle and epithelioid cell 102–3 310 naevus of Reed 290 polyembryoma 252 postpartum pigmented villonodular synovitis polymorphous low grade cervical smears 354 (PVNS) 341–2 adenocarcinoma (PLGA) 131 haemorrhage 52, 62, 385 JWBK208-IND-II August 12, 2008 16:22 Char Count= 0

Index of General Terms 411

post-traumatic cytology (effusions) 361 colon 148, 143, 146 fibro-osseous lesion (PTFOL) of the cytology (lung) 369, 370 dysplasia vs. 138, 148, 220 rib 334 fibrous dysplasia 334 effusion cytology 361 pseudoneuroma 317 fibrous pseudotumour 310, 324 endometrium 239 potassium deficiency 206 meningeal 186, 187 kidney (nephropathy) 207 pouchitis 147 mesothelial 153, 255, 360 larynx 82 pre-enclamptic toxaemia (PET) 61 ovarian 243–245, 374 liver 169, 168, 171 pregnancy 354, 372 pituitary 278 lung 370, 84 pregnancy 251 renal cell carcinoma 217 mesothelium 360, 89, 90 presentation skills 3 Schwannoma 315 neoadjuvant (colorectal cancer) 151, preservation injury (donor kidney) somatostatinoma 140, 178 47 208 thyroid 270, 271, 273, 367 neoadjuvant (oesophageal cancer) primary PSC 162, 163 136 arterial pulmonary hypertension 88 pseudoepitheliomatous hyperplasia neoplasia induced by 306, 327, 89, atrophic thyroiditis 268 (PEH) 133, 282, 285, 81 185, 263, 284, 285, 325, 335, 336 biliary cirrhosis 162–3 pseudolipomatosis coli 149 peritoneum 311 cutaneous CD30 +ve large T-cell pseudolymphoma 91, 263 prostate 223–4, 221 lymphoma 302 pseudomalignant osteoblastoma 335 salivary gland 133 dementias 181–2 pseudomelanoma 287 sarcoma 327 effusion lymphoma 109 pseudomelanosis skin 305–6, 304, 320 Fallopian tubal carcinoma 243 coli 147 small bowel 142, 141 intraosseous carcinoma 129 duodeni 126 thyroid 268, 368, 367 myxoedema 268 pseudomembranous colitis 143 urine cytology 365 neuroendocrine carcinoma of the pseudomyxoma peritonei (PMP) 254, radical prostatectomy 50 skin 294 375 radicular cysts 128 peritoneal carcinoma 255 pseudopolyp 149 radioisotope labelling 9 pigmented nodular adrenocortical pseudoxanthoma elasticum 78 radiotherapy see radiation disease 275 PTAH 10 ragged red fibres 189 sclerosing cholangitis 162, 163 pterygium 193 ragocytes 375 spermatocytes 211 PTFOL 334 rapamycin inhibitors 210 venous pulmonary hypertension 88 pulmonary rapid H&E staining 9–10 professional standards 32–3 emphysema 83 rapidly progressive crescentic progestagens 253 endodermal tumour resembling fetal glomerulonephritis 202–3 progressive generalised lung 92 reactive lymphadenopathy (PGL) 364 haemorrhagic syndromes 87–8 fibrous pleurisy 90 progressive systemic sclerosis (PSS) hypertension 69, 88 lymph node 109, 119–20, 363 71, 135, 301 lymphoid lesions 90–1 lymphoid follicles 112, 109, 101 progressive transformation of neuroendocrine proliferations 93 mesothelial hyperplasia 90 germinal centres 111 small cell carcinoma 248 mesothelial proliferations 359–60 proliferative pulseless disease 69, 70 rectum 46–7, 147, 148–9, 151, 139 endometrium 238 Purchaser/Provider contracting 33 recurrent fasciitis 311, 310, 228, 332 pustules in the skin 300 Hodgkin lymphoma 117 pilar tumour/cysts 292 PVNS 341–2 liver disease in the graft 166 retinopathy 195–6 pyelonephritis 206, 213 naevus 287 prostate pyloric mucosa 126 red cell disorders 122 adenocarcinoma 220, 222, 224 318, 319, 322, Reed-Sternberg cells 116 benign conditions 223–4 57, 129 reflux carcinoma 220–4 nephropathy 213 cut-up/reporting 42, 50 Q-fever 167, 22 oesophagitis 134–5 duct carcinoma 222–3 Queyrat erythroplasia 229 regenerative intraepithelial neoplasia 221 quick score 260–1 cartilage 340 immuno (of neoplasia) 18 Quilty lesions 77 muscle 189 postatrophic hyperplasia 221 polyp 138 specific antigen 18, 19 racemose aneurysms 72 regional myocardial infarction (MI) prostatic-type polyp 220 radial 75–6 prostatitis 215 alveolar counts 393 regressed follicles 111 protothecosis 81 growth phase melanoma 291 regression (in melanocytic lesions) protozoan infections 347–9 scars 262 287 Provision and Use of Work Equipment radiation / radiotherapy regulations 22 Regulations (PUWER) 22 angiopathy 72, 69, 207 Reinke’s space 82 prurigo nodularis 296 bladder 215, 220 Reiter’s disease 194 PSA 18–9 bone marrow 99, 103–4 rejection pathology see transplants psammocarcinoma 245, 255 brain / spinal cord 183, 185 relapsing polychondritis 86 psammoma 186 breast 263, 265, 266, 320, 373 renal psammoma bodies cervical smear 358 adenoma 216 cytology (breast) 373 cervix (endocervix) 236 amyloidosis 205 JWBK208-IND-II August 12, 2008 16:22 Char Count= 0

Index of General Terms 412

renal (Continued) rickets 329 haemangioma 94 autopsy 383 RIDDOR 22 lymphocytic lobulitis 263 biopsis 48–9 Riedel’s thyroiditis 268 mediastinitis 95 cell carcinoma 49, 216–17, 247, 361 right ventricular hypertrophy (RVH) papilloma 264 cut-up/reporting 41 391–2 peritonitis 153, 311 dysplasia 212 ring granuloma 101 pneumocytoma 94 failure 201 Rochalimaea spp. 14, 119, 319 polycystic adenosis 134 hypoplasia 212 Romanowsky 10, 8 stromal tumour 250 medullary carcinoma 217 Rosai-Dorfman disease 58, 15 sclerotic atrophy 221 oncocytoma 216 round cell liposarcoma 314 scorpion sting/venom 191 osteodystrophy 330 Royal College of Physicians, HCV screening program management 32 papillary necrosis 206 and 160 SCTAT 251, 52, 235, 249, 252 pathology 201–10 RSV 346 sebaceoma 294 tumours 216–18 rubeosis iridis 195 sebaceous lesions 294 see also transplants, polycystic and seborrhoeic dermatitis 296–7 other specific pathologies safety 1 seborrhoeic keratosis (SK) 282–3 reperfusion injury (donor liver) 165 SARS 22 secondary Reporting of Diseases and Dangerous St Mark’s pouchitis score 147 dementias 182 Occurrences at Work Regulations salivary M¨ullerian system 254–5 (RIDDOR) 22 duct carcinoma 131 polycythaemia 103 reporting guidelines 32–54 glands 113, 130–4, 368–9 pulmonary hypertension 88 research governance 26 Salmonella spp. 22, 143, 157, 167, spermatocytes 211 resections 44–54 173–4, 343, 346, 383 tumours see metastases, metastatic reserve cell hyperplasia 370 salpingitis isthmica nodosa 243 and radiation atypical 234 sarcoma see individual pathologies secretory endometrium 236–8 respiratory sarcomatoid segmental anatomy of the liver 41 bronchiole fibrosis 86 adrenal 276 seminal vesicle 220 cytopathology 369–71 breast 18, 264 seminiferous tubules 212 epithelial cells 370 cholangiocarcinoma 173 seminoma 225 pathology 81–95 colon 151 sensitivity 32 retention mucocoele 134 kidney 216, 217, 49, 214, 325, 327 sentinel nodes 118 reticulin 11 lung 92 sepsis 166–7, 383 retina 193, 44, 195–7, 199 prostate 223 septal panniculitis 303 retinoblastoma 44, 59, 199 thymus 96 sequestration 83 retinopathy 195–7 sarcomatoid transformation serious communicable diseases (SCD) retrolental fibroplasia 195, 196 chromophobe carcinoma 217 22 retroperitoneal renal cell carcinoma 216, 49, 214, serous fibrosis 311 325, 327 carcinoma of the peritoneum/ovary lymph nodes 228, 51 spermatocytic seminoma 225 153 retroperitoneum 309 sarcomatoid tumours cavities 359–63 retroplacental haematoma 62 carcinomas see ‘sarcomatoid cystadenoma 374 revalidation 32 carcinomas’ cystic tumours 177 rhabdoid chordoma 184 endometrial carcinoma 240–1 cells 314, 323 glioblastoma 185 microcystic adenoma 177 features, RCC with 216 granulosa cell tumour 249 ovarian tumours 244–5 features, RMS with 58 melanoma 362 psammocarcinoma of the inclusions 324 mesothelioma 90, 360, 17, 86, 89, peritoneum 255 melanoma 291 327 serrated adenoma 149–50 meningioma 186 spermatocytic seminoma 225 Sertoli PEComa vs. 326 Sarcoptes scabii 349, 304 cells 211, 227 SCC 284 scabies 349, 281, 304 tumours 227, 249, 246 tu mour 327 Norwegian (vs. pseudolymphoma) Sertoli-Leydig cell tumours 227, 246, tumour, extrarenal 324 307 249 tumour, gastric 139 vs. pemphigus 304 Service Level Agreements (SLA) 27 rhabdomyoma 79, 233, 78 scarring alopecias 295 SETTLE 272–3 rhabdomyosarcoma (RMS) 58, 309 Schistosoma spp. 349 severe dyskaryosis 356 rhabdomyomatous dysplasia 82 schistosomiasis 349, 88, 166, 168, sex cord tumours 227, 228, 249–51 rheumatic fever 76–7 214, 215, 311, 364 with annular tubules (SCTAT) 251, rheumatoid Schneiderian papilloma 81 52, 235, 249, 252 arthritis 340, 194, 360 Schwannoma 315 Shipman Inquiry 378 nodules 299 sclerema neonatorum 303 shock 383 vasculitis 71 scleroedema 301 shock lung (ARDS) 383 rhinoscleroma 81 scleromyxoedema 301 short surgical pathology cases (for the rhinosporidiosis 81 sclerosing exam) 2 Rhinosporidium seeberi 81 adenosis 262, 221, 134 sialadenitis 132–3 Rhizopus spp. 345–6 encapsulating peritonitis 311, 153 sialadenosis 369 JWBK208-IND-II August 12, 2008 16:22 Char Count= 0

Index of General Terms 413

sickle cell disease 122, 121, 195, 206, giant cell tumour 335 SRUS 149 347 osteoarticular 332, 335 staining 8–19, 90, 107–9, 188, 277, at autopsy 383, 378, 387 periprosthetic membrane 341 346, 353 sickle cell trait 217 sarcoma (cut-up/reporting) 52–3 star ratings system 33 signet ring 138, 139 soles of feet 281 status asthmaticus 86 carcinoma of stomach 138 solid microbiopsies of CIN 3 356 steatohepatitis 157–8, 168 lymphoma 110 solid pseudopapillary tumour steatosis 157, 168 melanoma 251 (pancreas) 177 stem villous hydrops 65 silicosis 85 solitary steroid cell tumour NOS 250 silver stains 10 bone cysts 333 Still’s disease 194 Singer’s node 82 circumscribed neuroma 288 adult 109, 115, 119 sinonasal lesions 81–2 fibrous tumour 94, 324 stomach 126, 137–41 sinus rectal ulcer syndrome 149 storage of specimens 31–2 B-cell reaction 109 Specialist Registrar (SpR) 26 storiform patterns 327 histiocytosis with massive Specialty Registrar (StR) 26 stratified mucinous intraepithelial lymphadenopathy 58, 15 specificity 32 lesion (SMILE) 235–6 lymphocytosis 109 specimen Streptococcus-associated diseases site selective antibodies 363, 17–8 handling 32–54 344 skeletal muscle 188–91 storage/disposal 31–2 stroke 381–2 biopsy handling 43 spermatids 211 stromal dystrophies 191 spermatocytes 211 deposits, corneal 196 fibre-selective atrophy 189 spermatocytic seminoma 225 hyperplasia, ovary 243 histochemistry 188 spermatogonia 211 hyperthecosis 243 myopathies 190–1 spermatozoa 211 luteoma 251 myositides 190–1 spinal cord 388–9 tumours, endometrial 242 normal morphology 189 spindle cell(s) tumours, gastrointestinal 140–1 regeneration 189 in fibrotic bone marrow 101 tumours, gonadal 226–7, 248, reinnervation 190 haemangioma 318 249–51 sampling at postmortem 389 lesions of childhood/infancy 57 Strongyloides stercoralis 350, 116, tumours 58, 309–310 lipoma 313 154, 349 skin 281–308 melanoma 290–1 struma cancers (cut-up/reporting) 48 tumours in lymph nodes 119 ovarii 251, 254 SLE 71, 76, 121, 204, 297–8, 360 see also sarcomatoid woody 268 small cell spindle and epithelioid tumour with strumal carcinoid 251, 253, 271 ALCL 116 thymus-like elements (SETTLE) strumosis peritonei 254 B-cell lymphomas 110 272–3 stucco keratosis 282 carcinoma of bladder 219 spindle sarcoma mimics 327 STUMP 241 carcinoma of breast 264 spirochaetes 344, 14, 109, 296, 340, styes 194 carcinoma of cervix 233, 234 346 sub-ependymal giant cell astrocytoma carcinoma of gallbladder 174 Spitz naevus 289–90 185 carcinoma of lung 93–4, 370 spleen 121–4 sub-involution of the placental site carcinoma of ovary, hypercalcaemic splenic MZL with circulating villous vessels 62 type 248 lymphocytes (SLVL) 124 sub-massive necrosis 158 carcinoma of ovary, pulmonary type spongiotic dermatitis (SD) 296 subchorial thrombus 62 248 spores 348 subcutaneous carcinoma of thyroid (medullary) spotty necrosis 158 fat necrosis of the new born 303 271 SpR see Specialist Registrars panniculitis-like T-cell lymphoma dysplasia 170 sputum 369–70 114 glioblastoma 185, 186 squamous subcutis 281, 392 melanoma 13, 152, 290 dysplasia 129, 136, 229, 233–4 subendocardial myocardial infarction mesothelioma 89 metaplasia 63, 148, 239, 354, (MI) 76 osteosarcoma 337, 336, 339, 16 355 subfertility 212 severe dyskaryosis 356 odontogenic tumours 129 sudden cardiac death (SCD) 76, 78, small intestine 141–3 squamous cell carcinoma (SCC) 385–6 SMILE 235–6 acantholytic 285 sugar tumours 95 smooth muscle alimentary tract 130, 133–4 sulphated mucins 12, 126, 137 myopathies 153–4 cut–up/reporting 44, 48 superficial tumour of uncertain malignant gynaecological 232, 234 angiomyxoma 317–18 potential (STUMP) 241 histological techniques 17 cells 353 tumours 241–2, 309 laryngeal 82, 45, 38–39 epithelioid malignant schwannoma smouldering myeloma 105 respiratory 81–2, 92 315 snake skin 284–5 suppurative cholangitis 166–7 skin (gastritis) 137 urological 219, 229 sweat gland differentiation venom 191 intraosseous (primary) 129 292 soft tissue 285–6, 309–28 squamous cell dyskaryosis Swiss cheese disease 263 chondroma 338 356 syncytial knots 61 JWBK208-IND-II August 12, 2008 16:22 Char Count= 0

Index of General Terms 414

syndrome respiratory distress, adult (ARDS) teratoma 59, 194, 225–6, 251–2 acquired immunodeficiency (AIDS, 383 terminal duct carcinoma 131 see also HIV) 165, 306–7, 346–7, respiratory distress, infantile 56 testicular 364 Reye’s 157, 168 appendage anomalies 213 acute chest 383 Sheehan 277, 383 lymphoma 228 Alagille’s 164, 69 short gut 141 tumours 50–1, 224–8 Albright’s 334 Shulman’s 301 testis 211–13 antiphospholipid antibody 61–2, Sipple 279 thecofibroma 250 351, 71, 160, 207 Sj¨ogren’s 194 spectrum 250 basal cell naevus 128 solitary rectal ulcer (SRUS) 149 thesaurocytes 104 Beckwith-Wiedemann 61, 65 Stein-Leventhal 244 thin membrane disease 205 brown bowel 147 Stevens-Johnson 297 threadworm 349 Budd-Chiari 169, 168 Stuart-Treves 320 thromboangiitis obliterans 71 Caplan’s 85 Sweet 300 thromboembolus 73 carcinoid 93 toxic shock 166, 383 thrombosis, portal vein 168 Carney 280, 317, 227, 315 tropical splenomegaly 167 thrombotic microangiopathy (TMA) Caroli 163 Trousseau’s syndrome 70 73, 207 Churg-Strauss 87, 71 twin-twin transfusion (TTTS) 63 thrombus 73 Cowden’s 326 vanishing bile duct 162 thymic CREST 135 vanishing bronchiole 84 cysts 57 Crow-Fukase 120 Verner-Morrison 178, 276 mass lesions 95–7 Cushing’s 97 wasting 346 thymoma 95–6 Down’s 156, 158, 162, 196 WDHA 178, 276 thyroid 267–73, 366–8 Dubin-Johnson 163 Zollinger-Ellison 178, 279, 140, 137 FNA grading/score 367 Ehlers Danlos 73 syndromic heart conditions 78 tumours (cut-up/reporting) 53 Eisenmenger’s 385 synovial timing 1 empty sella 277 chondromatosis 341 tissue storage/disposal 31–2 eosinophilia myalgia 88, 301 fluid 375 TNM classification 43, 46–50, 53–4 Felty 109 sarcoma 323 toxic myelopathy 103 Gardner 270, 282, 301, 334 synovium 339–42 toxicological tests 387 gay bowel 346 syphilis / syphilitic 296, 344 toxins see drugs and toxins Gilbert’s 156 aneurysms 72 Toxocara spp. 349, 87, 195 Goldenhar’s 193 brain 182 Toxoplasma spp. 347, 77 Goodpasture’s 87–8, 70, 201, 202, colorectum 346 AIDS 346, 364, 100 203 glomerulonephritis 203 brain / CSF 182, 364 Gorlin-Goltz 128 lymph nodes 109, 120 granulomas 347, 100, 101, 122, 167 growing teratoma 252 placenta 61, 63 heart transplants 77 haemophagocytic 101, 122, 286, skin 296, 303, 281, 295, 297 vs. Histoplasma 345 303 spleen 122 vs. Leishmania 349 HELLP 157, 385 stomach 137 trabecular carcinoma 294 Hughes’ 61–2, 351, 71, 160, 207 synovium / joints 340 trachoma and inclusion conjunctivitis hyperhaemolysis 383 uveitis 195 (TRIC) 195 Immune Reconstitution Disease vasculitis 69, 70, 72 tragi, accessory 199 Syndrome (IRDS) 307, 364, 182 syringocystadenoma papilliferum trans-urethral resection of prostate Jaffe-Campanacci 334, 331 (SCAP) 293 (TURP) 50 Kleinfelter’s 264 syringoma 293 transitional cell carcinoma (TCC) 18, Loeffler’s 87 systemic 49, 219, 247, 362, 365 Lyell’s 297 diseases, heart in 76 transitional cell papilloma 81 Maffucci’s 338 diseases, kidney in 204–5 transplants 114, 378 Marfan 78, 68, 73 hypertension 68–9 bone marrow 148, 166, 306, 85, 88, McLeod’s 83 lupus erythematosus 71, 76, 121, 101 MEA / MEN 279–80 204, 297–8, 360 heart 77–8, 386 Meckel-Gruber 163 mastocytosis 101–2, 122 kidney 207–10, 48, 203 metabolic 157 liver 165–6 Mikulicz 194 T-cell lymphoma (TCL) 114–16, 124 lung 84, 386 mucocutaneous lymph node Taenia soleum 350 pancreas 179 (MCLNS) 72 Takayasu’s disease 69, 70 transport of specimens 23 Muir-Torre 294 tall cell papillary carcinoma 270 traumatic neuroma 317 myelodysplastic (MDS) 102, 123 tamoxifen 254, 238, 358 trephines 99–106 nephritic 201 tamoxifen polyps 238 TRIC 195 nephrotic 201, 204 tapeworms 350 trichoadenoma 292 overlap 161, 163 TB see tuberculosis trichofolliculoma 292 painful bladder 214 temporal trichotillomania 295 POEMS 120 arteritis 69, 70 Tropheryma whippelii 344, 141 polycystic ovarian 244 artery biopsies 44 trophoblastic differentiation 226 pre-excitation 389 tendon sheath 341–2, 311 Trypanosoma cruzi 76, 347, 349, 383 JWBK208-IND-II August 12, 2008 16:22 Char Count= 0

Index of General Terms 415

tryptase 382 urticaria 299 co-infection 159 TTF-1 16 urticarial vasculitis 71, 299 inclusions 346, 212 tuberculosis (TB) 384, 344, 14, 22, usual interstitial pneumonia (UIP) 84 infections 346–7 85, 119, 239, 300, 311, 340, 383 uterine myocarditis 76 vs. Crohn’s disease 145 leiomyosarcoma 241 virus see specific types vs. Histoplasma 345 metaplasias 239–40 visceral Leishmaniasis 348–9 vs. Leishmania 349 smooth muscle tumours 241 Viva Voce 2 vs. MS (Devic’s disease) 183 uterus 42–3 von Meyenburg complexes (vMC) 164 see also granuloma, granulomatous, uveal melanoma 198 vulva 51, 232 AIDS, HIV uveitis 194, 195, 196 vulvectomy 51 tuberose sclerosis 16, 79, 93, 163, VZV 304 185, 216, 314, 326, 328 vacuolated fibres (muscle) 189, 153 tuboendometrioid metaplasia (TEM) vagina 232–3 wart 235, 357 vaginal intraepithelial neoplasia plane 283 tubular (VAIN) 232 plantar 283 carcinoma 262, 372 valve disease 77 myrmecia 283 necrosis 206 valves 75, 76, 78 Warthin’s tumour 133, 368 tubulitis 208 van Gieson 10 Weber-Christian disease 302 tubulointerstitial disease 206–7 van Nuys classification 258 weddelite 259 tufted 319 vanishing bile duct syndrome 162 Wegener’s granulomatosis (WG) 70, tularaemia 167 varicella-zoster virus (VZV) 304 87 tumour markers vas deferens 212 Weigart’s resourcin(ol) fuchsin 12 general 19 vascular weight ratios 393 germ cell 224 disease 206–7 weights (organ) 391–2 TURP 50 disorders 168–9 well-differentiated twin placentation 63 neurofibromatosis 73 liposarcoma 315 twin-twin transfusion syndrome pathology 68–74, 317–19 endrocrine tumours (pancreas) (TTTS) 63 rejection 208 178–9 typhoid 167 vasculitis 69–70, 76, 77 papillary mesothelioma 153 tyrosinaemia 170 fibrosing 299 thymic carcinoma 96 leukocytoclastic 71, 301 Whipple’s operation 40 UC see ulcerative colitis lymphocytic 301, 297, 263, 71 Whipple’s disease 142, 76, 137, 340 UIP 84 nodular 303, 69 WHO classifications 91–4, 95, 102, ulceration (in the GIT) 126–7 rheumatoid 71 104–5, 138–9, 178–9, 204–5, ulcerative colitis (UC) 144, 56, 143 SLE 71 219, 241, 245 DALM in 150–1 urticarial 299, 71 Wilms’ tumour 59–60 diversion and 147 veins 68, 70 Wilson’s disease 156–7 diverticular disease colitis vs. 146 vellus hair cysts 295 woody struma 268 dysplasia in 150 veno-occlusive disease (VOD) 88, 169 Workforce Development inflammatory polyps in 149 venous Confederations (WDCs) 25 squamous metaplasia and 148 aneurysms 72 workforce-related issues 23–6 strongyloides ulcerative enteritis vs. embolism 390 woven bone 329 350 pulmonary hypertension 88 WT1 16–17 undecalcefied sections 8, 11, 329 ventricular hypertrophy 391–2 X-rays 386 undifferentiated Verhoeff staining solution 12 xanthelasma 196 large cell carcinoma 92 verruca xanthogranuloma 299, 325 teratoma 226 plana 283 xanthogranulomatous pyelonephritis thyroid carcinoma 272 plantaris 283 214 242 verrucous carcinoma 285, 82, 130, Universal grading system (ovary) 248 229, 283, 51 yeast forms (of fungi) 345 urate vertebral arteries 388 Yersinia spp. 343, 119 nephropathy 207 vertical growth phase melanoma yolk sac tumour (YST) 226, 247, see also gout and crystals (VGP) 291 252 ureteric brushings 366 villitis 63 urinary villous Zimmerman’s tumour 194 bladder 41, 49 atrophy (small bowel) 142 Zimmerman stage 198 cytology 364–6 changes following IUD 62 ZN 14, 13, 119, 142, 148, 167, 200, urological pathology 211–31 fibrosis (placenta) 63 344–5, 349, 350 urothelial lymphocytes 124 zones (liver) 156 atypia 215 oedema 63 Zoon’s balanitis 215 differentiation 18 vimentin 17 Zygomyces spp. 370 tumours 218–20 viral zygomycosis 345–6 JWBK208-IND-III August 12, 2008 16:23 Char Count= 0

Index of Molecules 416

Index of Molecules

1ACT 100, 107 AST 157 CD1a 107, 15, 57–8, 94, 96, 109, 1 AT 83, 100, 107, 156–160, 162, ATPase 43, 156, 188 120–1, 281, 286, 325 164, 170, 172, 176–7, 223, 226, CD2 107, 96, 100, 102, 108, 115 302–3, 325, 335, 344 B72.3 362 CD3 107, 96, 100, 115–6, 121, 124, (TCR) 114 B-B4 100, 108 294 crystallin 181 Barium 148, 341, 32 CD4 107, 114–5, 121, 159, 165, 182, -lactalbumin 264 Bcl-1 (Cyclin D1, PRAD1) 107–8, 190, 302, 306, 307, 351 -subunit (pituitary) 277–8 100, 110, 113, 291 CD5 107, 110, 96, 101, 112–4, 232, -subunit of S100 15 Bcl-2 107, 16, 94, 101, 110–4,141–2, 272, 273 -synuclein 181 150–1, 235, 262–4, 272, 274, CD6 107 SMA 18, 57, 89, 92, 198, 293, 221, 284, 292, 313, 319, 323–4 CD7 107, 114, 116 223, 235, 249, 250, 265, 273, 279, Bcl-6 107, 110, 112–4, 117 CD8 107, 85, 114–6, 121–2, 126, 286, 309, 310, 312–3, 317–8, Bcl-10 107, 110, 112, 125 159, 165, 166, 171, 190, 208, 321–2, 324–6, 336, 338, 363 Ber-EP4 89, 153, 216–7, 360, 362, 307 -catenin 150–1, 246, 312 374 CD10 16, 107, 105, 112, 156, 172, -subunits (pituitary) 277 Beryllium 87, 101 217, 236, 284, 18, 104, 110, -subunit of S100 15 BG8 (Lewisy) 89, 362 113–5, 146, 216, 218, 242, 247, (TCR) 105, 114,124, 286, 205, 207 Brachyury 184 263, 266, 276, 292, 326, 363 (Ig light chain) 104, 9, 11, 108, BTA 366 CD11a 107 110, 205, 300 CD11c 108 : (ratio) 104, 9, 108, 112–3, 114, c-erbB-2 7, 259–60, 366 see also CD14 107, 100 205, 207, 300 HER2 CD15 107, 89, 100, 115–8, 247, 270, (Ig light chain) 104, 9, 11, 108, 110 c-kit (CD117) 16, 20, 50, 96, 98, 361–2 (see under ‘tau’) 100–2, 108, 131, 138, 140–1, CD16 107, 306 3OHSD 211 172, 216, 217–8, 224–5, 245, CD19 107, 100 5-HT 140 247, 263, 265, 294, 310, 320, CD20 107, 96, 100, 104–5, 109, 112, 34E12 14–8, 184, 220, 222–4, 234, 324, 326, 363 115, 117, 120–1, 141, 281 270–1, 385 C19 (of WT1) 17, 58 CD21 107, 110, 112–3, 115, 117, 121, A103 16, 227, 276 see also Melan-A C1q 202, 205 124 A4() 11, 72, 181 C3 70, 88, 185, 202–5, 208–9, 301, CD22 107–8 ACTH 178, 275–8 303–4, 305, 371, 388 CD23 107, 101, 110, 112–4 actin 161, 181, 312, 318, 322 see also C3bBb 203 CD24 107, 109 SMA, ASMA and MSA C3b-receptor 108 CD25 107–8, 100, 102, 105, 110, AE1/AE3 14, 17, 58, 66, 118, 156, C4d 77, 208–9 115–6, 121 184, 216, 225, 276, 294, 324 C9 202 CD28 100 AFP 7, 19, 50, 59, 139, 170–2, 223–6, Ca2+ plasma levels 274 CD30 107–9, 224–5, 302, 50, 91, 100, 247, 252, 276, 326, 362 Ca2+ oxalate 259, 267 104–5, 113, 115–7, 120–1, 122, aggrus 17 see also D2-40 Ca2+ in tissue 259, 265, 267 299, 362–3 ALC 161 CA-125 17, 19, 218, 235, 245–9, 253, CD31 107, 57, 265, 269, 315, 317–22, ALK (ALK-1) 57, 104–5, 107–8, 113, 270, 360, 362, 374 324–6, 344, 363 116, 120, 302, 310, 320 CA-19.9 17, 18, 19, 177, 235, 247 CD33 108 ALKM-1 160–1 cadherin(s) 261, 18, 218, 259 see also CD34 108, 140–1, 170–1, 317–26, 15, ALKM-3 160 specific types 57, 94, 105, 121, 138, 242, ALP 11, 15, 53, 332, 336, 337 CAE 107, 100, 123, 362 262–4, 269, 284, 292, 310–3, ALT 157, 162 CagA 135 315, 344, 363 AMA 161, 162, 163 178, 251, 269, 270–3 CD35 108, 121 AMACAR 17–8, 136, 218, 220–3 CALLA 16, 107, 105 see also CD10 CD36 108 AMAD-2 89 calponin 18, 130, 265 CD38 100, 108, 110, 362 amylase 11, 172–3, 176–7 calretinin 89, 90, 153, 211, 242, 249, CD42b 108 amyloid 11 see also specific types and 286, 326, 360, 362 CD43 108, 100–1, 110, 112–3, 120, see main index CAM5.2 14, 17, 62, 66, 93, 111, 178, 273 ANA 160, 161, 167, 297, 301 184, 219, 225, 276–8, 320 CD44 108, 264 ANCA 70, 87, 88, 161, 202 carbon (C) 13, 14, 85, 86, 183, CD45RA 108–9, 16, 94, 100, 104, aprotinin 8 341 113, 116–7, 121, 362 AR (androgen receptor) 232, 264, carbon monoxide (CO) 182–3, CD45RO 108, 100 292–3 387 CD56 108, 156, 93, 100, 107, argentaffin 10, 13, 140 carboxyhaemoglobin 387 114–6, 124, 152, 166, 178, asbestos 48, 85–6, 89, 371 carboxymyoglobin 387 219, 234, 276, 294, 306, 336, ASMA 167 caveolin 1 17 363

Diagnostic Criteria Handbook in Histopathology: A Surgical Pathology Vade Mecum by Paul J. Tadrous Copyright C 2007 by John Wiley & Sons, Ltd. JWBK208-IND-III August 12, 2008 16:23 Char Count= 0

Index of Molecules 417

CD57 108–9, 59, 117, 178, 186, ploidy (triploid) 65 desmoglein-1 303 312 rea.(12;q13) 58 desmoglein-3 303 CD58 100 t(1;13)(q36;q14) 58 DOG-1 140 CD61 108 t(1;14) 112 dystrophin 43, 191 CD63 108, 318 t(2;5) 113, 116, 302 CD68 108, 57, 94, 100, 102, 107, 121, t(2;13)(q35;q14) 58 EBNA 81 143, 225, 265, 278, 286, 310–2, t(4;14)(p16;q32) 104 E-cadherin 259, 261 324–6, 342, 362 t(11;14) 100, 110 EGFR 7, 151, 260 CD79a 108–9, 100, 105, 120–1, 141 t(11;18) 112 elastase (neutrophil) 70, 102, 109 CD99 16, 58–60, 81, 94, 96, 108, 141, t(11;22)(q24;p12) 58, 336 EMA 13, 16, 17, 50, 66, 81, 90, 91, 178, 184, 242, 249, 273, 294, t(11;22)(p13;q21) 58 94, 96, 100, 104, 108, 109, 323–4, 336–7, 339, 363 t(12;22) 324 116–7, 120–1, 130–1, 176–7, CD103 108 t(14;18) 101, 110, 111, 112 179, 184, 186–8, 200, 216–8, CD105 108 t(X;17)(p11.2:q25) 217 225, 228, 232, 234–6, 243, CD117 16, 20, 50, 96, 98, 100–2, 108, t(X;18) 323 245–9, 259, 270, 272, 276, 288, 131, 138, 140–1, 172, 216, trisomies 61, 65, 218 292–4, 302, 309, 312, 316–8, 217–8, 224–5, 245, 247, 263, trisomy 7 217 321, 323–4, 338–9, 360, 362–3 265, 294, 310, 320, 324, 326, 363 trisomy 17 218 ER (oestrogen receptor) 260–261, CD138 108–9, 17, 91, 100, 104, 362 Y- 218 17, 131, 141, 232, 235, 240–1, CD146 108, 65, 66, 237 chymotrypsin 177 247, 250, 259, 262, 264–5, CD171 108, 140–1, 310 CK (general) 14, 327 see also specific 292–3, 309, 317, 363 CD236 108 types erionite 86, 89 CD246 see ALK CK5 14, 262, 360 see also CK5/6 EWS (gene) 58, 336 CDX-2 151 CK6 14 see also CK5/6 CEA (general) 16–19, 59, 66, 89, CK5/6 15, 17, 18, 89, 90, 184, 258, fibrinogen 172 130–1, 152, 156, 164, 172–3, 265, 293 Fli-1 (antibody) 16, 294, 336 175–7, 184, 186, 217, 219–20, CK7 14–5, 17–8, 59, 94, 159, 162–3, FLI1 (gene) 58, 336 232, 234–6, 241, 245–6, 248, 172–3, 178, 184, 216, 217–8, FMC7 108, 101 251, 259, 270–272, 274, 276, 223, 232, 245–9, 259, 270–1, fodrin 258 292–4, 317, 320–1, 324, 360, 362 281, 292–4, 360, 363 FOX-P1 108, 113 CEA (monoclonal) 18, 164, 172–3, CK8 14, 15, 176 see also CAM5.2 FSH 254, 277, 278 241, 245–6 CK9 14 FVIIIRA 64, 207, 272, 317–8, 320–1, CEA (polyclonal) 16, 18, 89, 156, CK10 14, 17 324 172, 276 CK14 14, 17, 18, 130, 234, 265, 292 FXIIIa 108, 286, 312, 324–6 CgA () 10, 59, 93, CK15 284, 292 140, 152, 177–8, 184, 219, 234, CK17 14, 17, 184, 245–7, 265 galectin-3 184, 269, 270 267, 270–1, 273–4, 276, 279, CK18 14, 15, 227 see also CAM5.2 gastrin 137, 140, 178, 271 286, 294, 323 CK19 14, 15, 17, 172–3, 184, 245, GCDFP15 17, 131, 232, 292–3, 263 CgB (chromogranin B) 152, 178, 246, 262, 270 gelsolin 196 267, 274 CK20 15, 17–8, 94, 184, 218, 220, GFAP 15, 18, 130, 182, 184–8, 199, cholestyramine 148 223, 232, 245–8, 270, 284, 292, 200, 276–9 chromogranin see CgA and CgB 294, 360, 362–3, 366 GH 277–8 chromosomal anomalies clathrin 116 GHRH 178 [i(7q)] 124 cobalt 14, 84, 195 gliadin 142 [i(12p)] 225, 228 collagen I 11 glucagon 152, 178, 304 1− 218 collagen III 11 GLUT1 57, 318 2− 218 collagen IV 11, 324 glycophorin 102, 104, 108 see also 2+ 58 Copper (Cu) 12, 13, 156–7, 160, 162, CD236 6− 218 172, 196 glypican-3 19 6p (HFE) 156 cortisol 275 gp100 15 see also HMB45 3p− (VHL) 218 CuBP (polymerised metallothionein) GPC3 19 8+ 58 12, 157, 159, 160, 162, 172 GPIIIa see CD61 8p (LOH on) 218 cryoglobulin 70–1, 160, 203–5, 300, granzyme 107–9, 115–6 11+ 58 350 13q (LOH on) 218 crystallin 181 HBME1 269, 270 14q (Ig Heavy) 100 cyclin D1 (PRADl-1) see Bcl-1 HBcAg 160, 346 14q− 218 cytochrome oxidase 43, 188 HBeAg 160 androgenones 64 HBsAg 159, 160, 172 der(17) 217 D11 276 hCaldesmon 242 dmin 59 D2-40 (podoplanin) 17, 57, 89, 153, hCG 50, 59, 62, 65–6, 184, 219, HSR 59 184–8 224–6, 236–7, 243–4, 252, 277 ploidy (analysis) 9, 64, 65 DBA44 105, 108, 110 HDAC8 242 ploidy (aneuploid) 65, 170, 310 58, 60, 89, 90, 120, 141, 184, heavy chains 100, 108, , 110, 112, ploidy (hypodiploid) 218 191, 198, 242, 265, 286, 309–10, 205, 265 ploidy (polyploid) 65, 170, 237, 312, 317–8, 323–6, 342, 344, heavy metals 148, 84, 339, 341 283 360, 363 Hep Par 1 172–3, 276, 320 JWBK208-IND-III August 12, 2008 16:23 Char Count= 0

Index of Molecules 418

HER2 260, 7, 9, 17, 232, 265, 336 lipase 177 p53 90, 94, 109, 113–4, 136, 138, 142, histamine 140, 350, 382 LMP 108, 120 150–2, 173, 179, 185, 187, 218, HLA 57, 109, 208–9, 305 LP34 14, 18, 221, 223, 247, 362 220, 240–1, 263, 277, 284, 291, HLA-B8 305 lysophospholipase 370 310, 324–6, 360 HLA-DR 57, 109, 305 lysozyme 100, 108, 325, 344, p57 64 HMB45 15, 16, 81, 92–3, 95, 118, 362 p62 157, 172 120, 184–5, 216, 232, 242, M2A 17 see also D2-40 p63 18, 100, 108–9, 131, 218–9, 234, 249–50, 259, 290–1, 314–5, 320, MAC387 17, 20 264–5 322–4, 326, 363 MALT1 108, 110, 112 p105 185, 275 HMFG1 13 MART 1 16 see also Melan-A P504S see AMACAR HMFG2 13 mast cell tryptase 100–2, 382–3 PAX2 218 HNK-1 see CD57 MBP 108 see also lysophospholipase PAX5 109, 100 hPL 65–6, 237 mCEA see CEA (monoclonal) P-cadherin 18, 261 HPV 233, 22, 32, 51, 82, 129, 133, Mel-CAM (CD146) 66, 108 pCEA see CEA (polyclonal) 136, 232, 234, 283, 346, 354–6, Melan-A 16, 227, 232, 242, 249, PDGFR 140–1 358–9, 364 276, 290–1, 314, 320, 323, PECAM-1 see CD31 326 perforin 108–9, 116 Ig 100, 104, 109, 110, 165, 202, 205, mercury (Hg) 8, 14, 16, 148 peripherin 316 209, 303–5 see also specific mesothelin 17 PGM1 108 subtypes MIC-2 16 PGP 9.5 59, 178, 211 IgA 70, 108, 110, 112–3, 116, 126, MLH1 151 PgR (progesterone receptor) 201–3, 205, 293, 303–5, 351 MNF116 14, 89, 96, 184, 294, 363 260–261, 17, 131, 232, 235, 241, IgD 108, 110, 112–3, 133, 202 MOC-31 89, 153, 172, 216–7, 230 247, 250, 259, 261–2, 264–5, IgE 89, 108, 382 MPO 70, 100, 102–4, 108, 123, 292–3, 309, 317, 363 IgG 70, 88, 108, 112, 202–5, 208, 362 phosphorylase 188, 43 298, 301, 303–5, 347, 350–1, MSH2 151 Pit-1 277–8 382 MSH6 151 PLAP 50, 89, 90, 224–5 IgG4 133, 164, 175, 310–1, 328 MUC1 13, 217 see also EMA platelet glycoprotein IIIa see CD61 IgM 108, 110, 112–4, 133, 202–4, MUC2 13 PMS2 151 207–8, 350–1 MUC4 89 podoplanin 17, 153, 224 see also iodine/iodide 194, 267–8, 272, 368, MUC5AC 13 D2-40 11–3, 233, 344, 387 MUC6 13 polystyrene sulphonate 148 inhibin 65–6, 211, 242–3, 246–50, MUM1 100, 109, 290–1 PP 178, 276, 279 276, 286, 374 MyoD1 58, 363 PRAD1 (Cyclin D1) see Bcl-1 insulin 178 myogenin 58, 363 pRb 185, 275 IRF4 109 myoglobin 13, 188 PRL (prolactin) 277, 238, 278–9 myoglobulin 58 PSA 17–9, 50, 130–1, 218, 220–4, J-chain 108, 117, 305 myosin 43 see also smooth muscle 232, 363 myosin and ATPase PSAP 18, 218, 220, 222 kaolinite 86 PTH 274, 99, 300, 330, 335 Ki-1 (CD30) 13, 107, 120 see also NADH 43, 188, 190 PTHrP 178 CD30 NB84 59, 336 Ki-67 7, 57, 91, 93, 108, 110, 112–4, N-CAM 108 see also CD171 RCC MA 216–8, 247 130, 138, 152, 176, 178, 185–6, NCAM 108, 219 see also CD56 RET 270 188, 218, 220, 223, 234–5, 269, nestin 93, 140–1, 197–8 ret40f 102, 108 see also CD236 271, 274–7, 279, 284, 290–2, neu 7 see also EGFR rutile 86 294, 306, 324 neurotensin 178 kidney specific cadherin 218 NGF receptor 59 S100 15, 17–8, 57–9, 81, 90, 92–4, kip (p27) 211 NK1-C3 108, 318 100, 109, 118, 120–1, 130–1, Kip2 (p57) 64 NMP22 366 141, 184, 186, 188, 198, 200, KP1 108, 362 N-myc 59 211, 217, 221, 223, 227, 235–7, NP57 109 see also elastase 243, 245, 249, 259, 262, 265, L1 see CD171 N-ras 114 271, 276–9, 281, 286, 290–4, lactoferrin 70 NSE 50, 58–9, 81, 93, 152, 177–8, 309, 312–8, 320, 322–7, 335–6, laminin 62 184, 187–8, 211, 224–5, 276, 338–9, 344, 362–3 LCA see CD45RA 290, 294, 318, 323–4, 363 SAP 11, 146 lead (Pb) 148, 194 NSEst 103, 109, 190 serotonin 140, 179 lectin see Ulex SF-1 277–8 Leu-7 108 O13 16 silica 85, 101 Lewisx 19, 362 OCT2 117 silicates 85–6 Lewisy 19, 362 OCT4 184, 224–5, 252 silicone 215, 341, 373 LFA-1 107 oxytocin receptor 242 SM047 360 LH 254, 277–8 smooth muscle myosin 18, 265, 310 light chains 9, 11, 110, 112–4, 205, p16 185, 233, 235, 241 sodium [Na+] 183 207, 210, 300 see also , and p24 109, 182 somatostatin 140, 178 : p27 211 soya oil 373 JWBK208-IND-III August 12, 2008 16:23 Char Count= 0

Index of Molecules 419

spectrin 43, 102, 104, 108 200, 269–74, 320, VEGF-1 88 stromelysin 3 284, 292 363 VHL 177–8, 187, 200, 218 strontium (Sr) 148 TIA-1 107–9, 115–6, 124 vimentin 17, 58, 60, 79, 90, 94, 100, substance P 179 titanium (Ti) 84, 86, 341 121, 131, 139, 177, 179, 184, succinate dehydrogenase 188, 190 transferrin 157 186–8, 198, 200, 216–7, 227, surfactant 94, 363 transthyretin 188 236, 241–3, 245–7, 249–50, 272, SV40 large T Ag 209 TRAP 100, 105, 109–10, 123 276, 284, 290, 310, 312–3, 317, 58, 93, 152, 178, trk 59 320–2, 324, 326, 335–6, 338, 187–8, 219, 276, 278, 294, 323 trypsin 176, 177 362, 363 Syndecan-1 108, 100 tryptase 100–2, 382–3 VIP 178, 276 TSH 267, 277–8 VMAT-2 140 T3 (free) 267 TTF-1 16–7, 89, 93, 172, 223, 269, vs38c 100, 104, 108–9 T3 (total) 267 294, 360, 362–3 T4 (free) 267 TTF-1 (cytoplasmic) 16, 172 weddelite 259, 267 tau (protein) 11, 181 tTG 142, 305 WT1 16–7, 58, 60, 89, 211, 245–7, Tdt 16, 96, 104–5, 109, 114, 294, tungsten (W) 84 374 363 WT1 (gene) 60 tetrazolium reductase 188 ubiquitin 157, 172, 181 WT2 (gene) 60 TFE3 217, 323 UCHL1 see CD45RO TGF 196 Ulex (europaeus lectin) 217, Zap-70 109 thrombomodulin 18, 89, 247, 317 zinc (Zn) 8, 148, 304 360 uroplakin 17–18, 247, 363 zirconium (Zr) 341 JWBK208-IND-I December 14, 2007 13:31 Char Count= 0

Index of Eponyms 420

Index of Eponyms

For more on medical eponyms, including those not found in this book, try this web site by Ole Daniel Enersen www.whonamedit.com (last accessed 25 November 2007)

Addison 141 Brown 343, 348 Devic 183 Alagille 69, 162, 164 Bruch 44, 193, 197 Dieterle 14 Albers-Sch¨onberg 330 Brunner 126, 142 D¨oderlein 354 Albright 334, 4 Buck 42 Donovan 109, 343 Allred 260 Budd 168–9 Dorfman 15, 58, 286, 303 Alport 201, 205 Buerger 69–71 Douglas 42 Alzheimer 11, 72, 181–2, 381 Burkitt 47, 100, 107, 109, 113–4, Down 156, 158, 162, 196 Ammon 36 142, 253, 346, 362–3 Dressler 76 Antoni 315 Bushke 285 Dubin 163 Arias 232, 236, 237, 243–4, 253–4, Dupuytren 311 335 Caldicott 30–1 D¨urck 348, 351 Arthus 350 Call 227, 249, 252 Dutcher 104, 361–2 Aschoff 76–7, 174 Calman 25–6, 29–30, 33 Duval 226 Askanazy 267, 367 Campanacci 331, 334 Askin 58, 91, 336 Camper 39 Ehlers 73 Auer 102 Caplan 85 Eisenmenger 385 Ayre 353 Carneiro 138 Ellison 178, 279, 140, 137 Azzopardi 93–4, 219 Carney 140, 227, 275, 280, 315, 317 Erdheim 94, 286 Carnoy 7 Evans 132 Banff 165, 201, 208–9 Caroli 163, 213 Ewing 58, 335–6, 337, 339, 342, 361, Barr M.L. 353 Castleman 97, 100–1, 111, 114, 16, 108, 327, Barr Y.M. see Epstein-Barr virus in 119–20, 124, 304, 321, 347 330, 333 main index Catalona 39 Exner 227, 249, 252 Barrett 45, 135–6 Chagas 76, 135, 349 Barr´e 183 Charcot 36, 68, 103, 211, 370, 382 Fabry 206, 285 Bartholin 232 Chester 94, 286 Fallop 243 Bazin 69, 300, 303 Chiari 168–9 Fallot 386 Becker P.E. 191 Christian 58, 122, 299, 302, 331 Faraco 344 Becker S.W. 287 Churg 69–71, 87, 215, 303, 360 Felty 109 Beckwith 61, 65 Civatte 297, 306 Feulgen 7, 13 Bednar 325 Clara 91, 361 Finkeldey 119, 331, 346 Beh¸cet 71, 144–5, 183, 194, 301, Clark 291, 48 Fite 14, 119, 344 340–1 Cloquet 39 Fleischer 196 Bell 95 Colles 39 Fluhman 235 Berger 203, 205 Conn 275 Fontana 13, 362 Bernatz 95 Councilman 157, 159, 163, 166 Fordyce 232, 281, 285 Bilharz 349 Cowper 18, 42, 222 Fouchet 13 Billroth 40, 121 Coxsackie 76 Fox 232, 281 Binswanger 182 Creola 369 Fuch 196 Birbeck 57, 109, 120–1 Crohn 144–5, 4, 70, 127, 137, 143, Fuhrman 218, 276 Borrmann 45 146–9, 194, Fujimoto 72, 119 Borst 282–3, 292 303, 340 Fukase 120 B¨ottcher 211 Crooke 277–8 Fulton 391 Bouchard 68 Crow 120 Bouin 7, 8, 19, 176, 225 Curschmann 362 Gallyas 10 Bowen 229, 232, 259, 282–4, 287, Cushing 93, 97, 275 Gamna 79, 122 292, 294 Gandy 79, 122 Bowman 193, 196, 203, 205 Dabska 306 Gardner 270, 282, 301, 334 Braak 181 Danlos 73 Gartner 236, 16, 232 Brenn 343, 348 Darier 304 Gaucher 123, 99, 101, 196, 58, 100, Brenner 228, 245, 247 Davies 386 122, 142 Breslow 48, 118, 198, 291 de Quervain 268, 331, 367 Gerota 49 Brill 112 Degos 283 Gerstmann xvii, 182, 381 Brocq 295, 298 Denonvilliers 42 Giemsa xix, 10, 13, 14, 47, 102, 195, Broders 284, 229 Dercum 281 271, 300, 343–4, 347–8, 359, Brodie 330, 334 Descemet 193, 195–6 361–4, 368, 370, 374–5

Diagnostic Criteria Handbook in Histopathology: A Surgical Pathology Vade Mecum by Paul J. Tadrous Copyright C 2007 by John Wiley & Sons, Ltd. JWBK208-IND-I December 14, 2007 13:31 Char Count= 0

Index of Eponyms 421

Gilbert 156 H¨urthle 251, 267–70, 273–4, Lowenstein 285 Gimenez 14 367–8 Luce 378 Gleason 222–4, 18, 50, 215, Lugol 11, 12, 344, 387 220–1 Isaacson 127, 136 Luschka 174 Goldenhar 193 Ishak 159 Lyell 297 Goldner 11, 329, 8 Ito 287 Lyme 340 Golgi 109, 116, 278 Goltz 128 Jadassohn 282–4, 292 Maffucci 318, 338 Gomori 12, 43, 99, 188–9, 191 Jaffe 331, 334 Makin xiv see also CAM5.2 in Goodpasture 70, 84, 87, 201–3 Jakobiec 198 molecules index Gordon 10, 11 Jass 151 Malherbe 293 Gorlin 128, 250 Jeghers 138, 149, 235, 251 Mallory 156–7, 159–60, 162–4, Goseki 138 Jessner 297 169–72 Gough 48 Johnsen 212 Marchi 13 Gram 14, 81, 167, 199, 304, 343–4, Johnson 163, 297 Marfan 68, 73, 78 348 Jones 10 Martius 10, 11, 73 Graves 267, 350, 367 Masson 10, 11, 13, 84–5, 99, 321, Grenz 197, 282, 294, 299, 301, Kaposi 322–3, 364, 4, 16, 119, 362, 389 325 320 May xix, 271, 361–4, 368, 370, 374 Grimelius 10, 140, 264, 271 Kasai 164 see also Giemsa Grocott 10, 81, 167, 346–7, 364 Kaserbach 322 McLeod 83 Grover 304 Kawasaki 70, 72, 76, 119 McMullen 14 Gruber 163 Kayser 196 Meckel 163 Gr¨unwald xix, 271, 361–4, 368, 370, Kikuchi M. 72, 119, 363 Meibom 194 374 Kikuchi R. 151 Meig 250 see also Giemsa Kimmelstiel 204 Meissner 287, 316 Guillain 183 Kimura 318 M´en´etrier 137 Gutmann 214 Kleinfelter 264 Merkel 294, 15, 16, 94, 108–9, 281–2, Klippel 318 284, 336 Habermann 298 Kl¨oppel 176 Merritt 322 Haggitt 151 K¨obner 283, 296, 298 Meyer 12 Hailey 304 Koch 39, 390 Mibelli 285 Hale 12, 216–7 Kogoj 296 Michaelis 214 Hallopeau 303 Kolopp 302 Mikulicz 81, 194 Hamman 84 Krukenberg 249, 19 Milwaukee 340, 375–6 Hand 58, 122, 331 Kupffer 156, 158, 160, 164, 167–71, Ming 138 Hansemann 214 348 Mohs 48 Harris 10, 353 K¨uttner 133, 311 Moll 194 Hart 245 Morgagni 213, 38, 196 Hashimoto 267–8, 271, 273, Lagios 258 Morrison 178 367–8 Lambert 92 Morton 317 Hassall 57, 96, 196 Lambl 75, 79 Mott 104 Heidenhain 13 Langerhans 15, 57, 94, 107, 109, 120, Movat 10 Henle 196 177–8, 281, 286, 325, 333 Mucha 298 Henoch xvii, 70–1, 201–2, 301 Langhans 62, 167 Muir 294 Herring 277 Lassa 22 M¨uller 118, 153, 228, 232, 235, 242, Hine 29–30, 33 Lattes 95 245, 248, 254, 361 Hirano 181 Laur´en 46, 138 M¨uller-Hermelink 95 Hirschprung 56 Le Veen 311 Munro 296 His 39, 390 Leder 107 Hodgkin 81, 97, 103–5, 109, 114, Leishman 343 see also main index Naboth 232, 235 116–9, 362–3 Lendrum 10, 385 Nakagawa 319, 57 see also Reed D. Lennert 102 Neelsen xxiii, 14, 13, 119, 142, 148, Hoeppli 344, 349 Letterrer 58 167, 200, 344–5, 349, 350 Hoescht 13 Leventhal 244 Negri 346 Hoffman 190 Levine 95 Neumann 303 Hofmeister 40 Lewis 19, 362 Nikolsky 281, 297, 303 Homer-Wright 59, 188, 199 Lewy 181, 182, 135 Nissl 185, 14 Hopf 282 Leyden 370, 103 Nitabuch 236 Hopps 343 Leydig 211, 15, 213, 227, 243, 249, Norris 245 Horny 102 52, 245, 246, 250, 251 Horsfall 205, 365 Libman 76 Oddi 174 Huet 102 Lindau xxii, 177–8, 187, 200, Ollier 338 Hughes 351 218 Orphan Annie 4, 269, 273 Hunner 214 Lisch 316 Ota 197, 287 Huntingdon 182 Loeffler 87 Pacini 315 JWBK208-IND-I December 14, 2007 13:31 Char Count= 0

Index of Eponyms 422

Page 258 Schiller 226 van der Waals 12 Paget 330, 259, 232, 286–7, 14, 15, Schlagenhaufer 123 van Gieson 8, 10–3, 44, 47, 88, 130, 17, 51, 93, 114, 173, 175, 219, 225, Schmincke 81 214, 311 260, 262–3, 281–2, 288–90, 292, Schmorl 13, 14 van Nuys 258 294, 302, 325, 329, 334, 336 Schneider 81, 200 Vater 174, 14, 40, 46, 173 Palade 317, 285 Sch¨onlein xvii, 70–1, 201–2, 301 Verhoeff 12 Paneth 10, 11, 126, 137, 138, 144, Sch¨uller 58, 122, 331 Verner 178 152, 177, 224 Schwann 315–7, 15–7, 138, 140–1, Verocay 315 Papanicolaou 353, 14 152, 184, 187, 280–1, 291, 320, 324 Vienna 127 Parkinson 182 Sertoli 211, 227, 249, 246 Virchow 168, 169 Parwaresch 102 S´ezary 299 von Brunn 219 Pautrier 296 Sheehan 277, 283 von Hippel xxii, 177–8, 187, 200, Pelger 102 Sheinker xvii, 182, 381 218 Perls 13, 12, 47, 86–7, 99, 171, 349 Shikata 172 von Kossa 8, 11, 77, 214, 329 Peutz 138, 149, 235, 251 Shimizu 248 von Meyenburg 164, 173 Peyronie 311 Shipman 378–9 von Recklinghausen 316 Pick A. 181, 381 Shulman 301 von Willebrand see FVIIIRA in the Pick L. 213, 227 Siewert 45 molecules index Pindborg 129 Simchowicz 181 Pinkus 284 Sipple 279 Wade 344 Polya 40 Siwe 58 Wagner 287 Pompe 78 Sj¨ogren 160, 162, 194 Waldenstr¨om 141, 205, 207, 350 Potter 213, 56 Skene 18 Waldeyer 38, 114 Price 228 Smith 378 Walthard 152 Purkinje 17, 383 Sommer 36, 383, 388 Warthin 14, 119, 132–3, 270, 296, Spicer 12 319, 331, 346, 348, 368–9 Queyrat 229, 215 Spitz 15, 197, 286, 289–91, 324 Weber 299, 302 Quilty 77 Splendore 344, 349 Wegener 70, 76, 87, 95, 215, 301 Starry 14, 296, 319, 348 Weibel 317, 285 Rathke 184, 277–9 St¨aussler xvii, 182, 381 Weigart 12 Raynaud 350 Stein H.J. 45 Wentworth 48 Reed D. xxi, 16, 105, 107–9, 113, Stein I.F. 244 Werdnig 190 114–8, 120, 299, 342, 362–3 Stella 232, 236, 237, 243–4, 253–4, Wermer 279 Reed R. 286, 289–90 335 Wernicke 385 Regaud 81 Sternberg xxi, 16, 105, 107–9, 113, Whipple A.O. 40 Reid 83 114–8, 120, 299, 342, 362–3 Whipple G.H. 142, 344, 76, 137, Reinke 38, 227, 249–51, 361 Stevens 297 141, 340 Reiter 72, 194, 340 Still 194, 109, 115, 119 Wiedemann 61, 65 Reye 157, 168 Stocker 82 Willemze 299, 302 Rich 84 Strauss 69–71, 87, 215, 303, 360 Willis 68, 381, 390 Richter 105, 110 Stuart 320, 263 Wilms 16, 58–60, 212, 228, 243 Riedel 267–8, 272–3, 311 Sutton 288 Wilson C. 204 Riopel 245 Sweet 300 Wilson S.A.K. 156–60 Rokitansky 174, 392 Sweets 10, 11 Wirsung 174 Romanowsky 10, 8 see also Giemsa Sylvius 36, 388 Wolff 232, 236, 243 Rosai 15, 58, 95, 286, 303 Symmers 112, 349 Woringer 302 Rosenm¨uller 39 Rosenthal 184–5, 187 Takayasu (Takayashu) 69–70 Zahn 73, 168 Roux 40 Tamm 205, 365 Zeiss 194 Rushton 128 Tavassoli 258 Zelger 286 Russell 104, 10, 82, 199, 300 Todaro 39 Zellweger 162 Toker 259–60, 281 Ziehl xxiii, 14, 13, 119, 142, 148, 167, Sacks 76 Torre 294 200, 344–5, 349, 350 Sanderson 267, 270 Touton 94, 286, 325, 331 Zimmerman 198, 194, 197 Santorini 174 Trenaunay 318 Zollinger 178, 279, 140, 137 Schaumann 87, 147, 194 Treves 320, 263 Zoon 215 Scherer 187 Trousseau 70 Zukerkandl 11, 279