Molecular Cancer BioMed Central Research Open Access Androgen-regulated genes differentially modulated by the androgen receptor coactivator L-dopa decarboxylase in human prostate cancer cells Katia Margiotti†2,3, Latif A Wafa†1,2, Helen Cheng2, Giuseppe Novelli3, Colleen C Nelson1,2 and Paul S Rennie*1,2 Address: 1Department of Pathology and Laboratory Medicine, Faculty of Medicine, University of British Columbia, Vancouver, BC, V6T 2B5, Canada, 2The Prostate Centre at Vancouver General Hospital, 2660 Oak Street, V6H 3Z6, Vancouver, BC, Canada and 3Department of Biopathology and Diagnostic Imaging, Tor Vergata University of Rome, Viale Oxford, 81-00133, Rome, Italy Email: Katia Margiotti -
[email protected]; Latif A Wafa -
[email protected]; Helen Cheng -
[email protected]; Giuseppe Novelli -
[email protected]; Colleen C Nelson -
[email protected]; Paul S Rennie* -
[email protected] * Corresponding author †Equal contributors Published: 6 June 2007 Received: 27 March 2007 Accepted: 6 June 2007 Molecular Cancer 2007, 6:38 doi:10.1186/1476-4598-6-38 This article is available from: http://www.molecular-cancer.com/content/6/1/38 © 2007 Margiotti et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: The androgen receptor is a ligand-induced transcriptional factor, which plays an important role in normal development of the prostate as well as in the progression of prostate cancer to a hormone refractory state.