Authors: Pallavi Subhraveti Ron Caspi Peter Midford Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_001664545Cyc: Rhizobium sp. N741 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari pro a dicarboxylate an amino an amino an amino an amino an amino an amino an amino an amino glycine betaine acid acid acid molybdate an amino acid acid acid acid acid an amino sulfate arsenite sn-glycerol acid an amino an amino an amino an amino acid molybdate ammonium molybdate D-xylose predicted 3-phosphate acid acid acid acid predicted predicted predicted predicted predicted predicted predicted predicted predicted ABC ABC ABC ABC ABC ABC ABC ABC ABC ABC transporter CcoS RS32175 RS24260 RS24235 RS24230 RS24070 RS22995 RS10550 RS21135 RS28395 RS07875 TolQ RS02515 RS03820 RS19105 YajC RS09790 ArsK RS20585 RS24115 XylF RS24250 RS24325 RS25035 UgpC RS15380 RS15005 RS27235 RS20540 RS31790 transporter transporter transporter transporter transporter transporter transporter transporter RS12545 ModC RS26725 transporter of L-proline/ predicted of an of an of an of an of an of an of an of an of molybdate glycine ABC urea urea betaine amino acid amino acid amino acid amino acid amino acid amino acid amino acid amino acid transporter sulfate arsenite an amino of urea molybdate ammonium D-xylose sn-glycerol an amino an amino an amino an amino an amino molybdate acid 3-phosphate acid acid acid acid acid molybdate an amino an amino an amino an amino an amino an amino an amino an amino predicted pro a dicarboxylate ABC acid acid acid acid acid acid acid acid choline choline glycine betaine transporter of choline RS24190 Amine and Polyamine Degradation Degradation/ predicted tRNA-uridine 2-thiolation Macromolecule Modification Utilization/ 4 N 6 -(3-methylbut- ditrans,octacis- a peptidoglycan with a [protein]- an O - a mature an N-terminal- an N-terminal- queuosine at a (1->4)- ABC cob(II)yrinate a,c- Cofactor, Carrier, and Vitamin Biosynthesis Fatty Acid and Lipid Biosynthesis and selenation (bacteria) Assimilation - Other a sulfurated a NifEN a NifB protein menadione NADH + a [glutamine- a ribonucleoside an L-asparaginyl- an L-cysteinyl- ectoine ectoine [2Fe-2S] iron-sulfur NADP flavin biosynthesis I (bacteria and plants) superpathway of tetrahydrofolate biosynthesis and salvage superpathway of heme b NAD de novo biosynthesis ectoine degradation 2-en-1-yl)- undecaprenyldiphospho- (L-alanyl-γ-D-glutamyl- methylthymine H peptidoglycan L-methionyl-L- L-methionyl-L- glu position 34 α-D-glucan transporter cob(II)yrinate a,c-diamide superpathway of thiamine diphosphate biosynthesis II ethanolamine utilization L-carnitine degradation I L-cysteine (n) ATP diphosphate Asn Cys dGDP diamide biosynthesis I allantoin degradation choline-O-sulfate 4-aminobutanoate allantoin degradation L-carnitine degradation II [sulfur carrier] 37 protein complex with an L-cluster synthetase]- [tRNA ] [tRNA ] Asp cluster biosynthesis biosynthesis biosynthesis from glutamate I (from aspartate) acrylonitrile adenosine N-acetyl-(N-acetyl-β-D- L-lysyl-D-alanyl-D- in DNA (meso-DAP threonyl-[protein] vitamin B12- alanyl-[protein] of a tRNA 1,4-alpha- of ectoine biosynthesis II (late degradation degradation I to glyoxylate I (early cobalt insertion) palmitate biosynthesis (type II fatty acid synthase) cys to glyoxylate III degradation I in tRNA glucosaminyl)muramoyl- alanine) pentapeptide containing) L-tyrosine vitamin B12- glucan cobalt incorporation) octanoyl-[acyl-carrier ectoine dependent + gondoate biosynthesis dependent branching + + uroporphyrinogen-III NAD GTP asp cys a [ThiS sulfur- ectoine ethanolamine L-carnitine L-carnitine L-alanyl-γ-D-glutamyl-L- bifunctional helix- NADH-quinone ribonucleotide H RS25160 H uroporphyrinogen-III L-cysteine desulfurase GTP glu protein] biosynthesis (anaerobic) cysteine (S)-(+)-allantoin choline sulfate 4-aminobutanoate (S)-(+)-allantoin nitrogenase type I methionyl aminoacyl- type I methionyl aminoacyl- tRNA uroporphyrinogen-III carrier protein] carnitine 3- acrylonitrile tRNA (N6-isopentenyl lysyl-D-alanyl-D-alanine turn-helix domain- oxidoreductase: bifunctional [glutamine ribonucleotide protein NAD kinase: glutamate-- L-aspartate (mitochondria, yeast) hydrolase hydroxyectoine iron- lytic aminopeptidase: reductase: tRNA aminopeptidase: tRNA glutamyl- uroporphyrinogen-III cysteine an acetoacetyl-[acp] desulfurase: allantoinase choline- 4-aminobutyrate- allantoinase dehydrogenase: nitrile hydratase: adenosine(37)-C2)- containing protein/ AMK03_RS08065 reductase: GlgB: glgB C-methyltransferase: cysteine AMK03_RS08295 bifunctional GTP tRNA ligase: oxidase: DoeA: doeA molybdenum transglycosylase synthetase] map AMK03_RS08825 hydrolase: map hydrolase: Q(34) C-methyltransferase: desulfurase: a malonyl-[acp] an oleoyl-[acp] AMK03_RS11275 (2S)-2-acetamido- utilization PuuE: puuE sulfatase: betC -2-oxoglutarate PuuE: puuE nthB nthA methylthiotransferase AMK03_RS08070 AMK03_RS08825 cobA desulfurase: + AMK03_RS19060 AMK03_RS27650 an acetoacetyl-[acp] AMK03_RS22855 methylated-DNA-- adenylyltransferase/ 1,4-alpha- + + cobA NADP 3,4-dihydroxy- cyclohydrolase an L-glutamyl- 3-oxoacyl-[acyl- dehydratase transaminase: monofunctional cofactor domain-containing type I methionyl class 1b arfB type I methionyl arfB synthetase H RS18310 H 2-iminosuccinate AMK03_RS11275 [+ 2 isozymes] 4-aminobutanoate allantoate choline allantoate 3-dehydrocarnitine acrylamide MiaB: miaB [protein]-cysteine S- AMK03_RS08080 [glutamine synthetase]- class 1b uroporphyrinogen-III AMK03_RS11275 2-butanone- Glu 3-oxoacyl-[acyl- biosynthetic biosynthesis protein: GluQRS: glucan I FolE: folE [tRNA ] a carboxy- carrier-protein] an [L-cysteine EutB: eutB (R)-carnitinyl-CoA AMK03_RS00480 aminopeptidase: ribonucleoside- aminoacyl-tRNA aminopeptidase: aminoacyl-tRNA C-methyltransferase: uroporphyrinogen-III 4-phosphate 7,8- [+ 2 isozymes] carrier-protein] N-alpha-acetyl succinate succinate methyltransferase: AMK03_RS08095 adenylyl-L-tyrosine ribonucleoside- branching [+ 2 isozymes] adenylated- reductase: fabG beta-ketoacyl- desulfurase]-S- crotonobetainyl- choline peptidoglycan protein AMK03_RS14865 map diphosphate hydrolase: map hydrolase: gluQRS C-methyltransferase: quinolinate an [L-cysteine diaminobutyric semialdehyde amidase: dehydrogenase, AMK03_RS19150 nuoH nuoI phosphorylase: diphosphate cobA synthase/GTP dihydroneopterin reductase: fabG sulfanyl-L-cysteine acetaldehyde CoA dehydrogenase: transglycosylase: NifN: nifN [+ 10 isozymes] reductase: AMK03_RS15625 AMK03_RS15625 protein cobA an S-sulfanyl-[L- synthase desulfurase]-S- [ThiS sulfur- beta-ketoacyl- ACP synthase acid AMK03_RS27090 AMK03_RS08110 H + FliI H + precorrin-1 cyclohydrolase II: 3'-triphosphate D-glyceraldehyde beta-ketoacyl- hydratase: caiD betA NAD-dependent hydrophobic mtgA methylated-DNA-- AMK03_RS06585 reductase: GlgB: glgB precorrin-1 cysteine desulfurase] NadA: nadA sulfanyl-L-cysteine carrier protein] ACP reductase: I: fabB deacetylase amidase: nitrogenase nuoK an N-terminal L- a 2'- nrdF nrdE an N-terminal L- glutamyl- a (1,6)-α-D- AMK03_RS24205 3-phosphate ACP reductase: queuosine biosynthesis I (de novo) succinate- membrane anchor [protein]-cysteine S- nrdF nrdE uroporphyrinogen-III (S)-4-amino-5- AMK03_RS20820 [+ 2 isozymes] DoeB: doeB alcohol (S)-ureidoglycine (S)-ureidoglycolate trimethylaminoacetone AMK03_RS01115 iron- AMK03_RS08125 a mature GlcNAc-1,6- met threonyl-[protein] deoxyribonucleoside met alanyl-[protein] queuosine at glucosyl-(1,4) 2,5-diamino-6- quinolinate AMK03_RS20820 betaine aldehyde semialdehyde protein: sdhD methyltransferase: a [glutamine GDP C-methyltransferase: uroporphyrinogen-III oxopentanoate 1-deoxy-D- cysteine a [TusA sulfur- dehydrogenase a peptidoglycan with di-trans,octa-cis molybdenum peptidoglycan anhMurNAc- asn tRNA Asn cys a tRNA Cys position 34 (5-phospho-D- a (3R)-3- nuoN (n) 5'-diphosphate -α-glucan gly (S)-ureidoglycine dehydrogenase: ureidoglycolate Asp C-methyltransferase: 7,8- xylulose-5- L-2,4- γ acrylate 6 γ AMK03_RS01495 synthetase]-O cobA desulfurase: a (3R)-3-hydroxybutanoyl-[acp] carrier protein]-S- preQ AdhP: adhP -butyrobetainyl- crotonobetainyl- betaine-aldehyde (L-alanyl- -D-glutamyl- -undecaprenyl cofactor (meso-DAP L-Ala-γ-D-Glu- of a tRNA + F0F1 ATP + ribosylamino) glutamate-1- carboxylating hydroxybutanoyl-[acp] 0 N -(3-methylbut- 4 H H cobA an S-sulfanyl-[cysteine dihydroneopterin phosphate AMK03_RS11275 an (11Z)-3-oxo- diaminobutanoate acetyl-CoA aminohydrolase: CoA CoA AMK03_RS10760 lyase: 5'-deoxyadenosine an unsulfurated diphosphate [+ 2 isozymes] -(5'-adenylyl) synthase uroporphyrinogen-III pyrimidin- semialdehyde sulfanyl-L-cysteine NADPH-dependent 7- dehydrogenase: 2-en-1-yl)-2- met L-lysyl-D-alanyl-D- biosynthesis containing) DAP-D-Ala nicotinate- glycine 3-hydroxyacyl- icos-11-enoyl-[acp] AMK03_RS27210 [+ 5 isozymes] AMK03_RS16165 -L-tyrosine uroporphyrinogen-III desulfurase]-[disordered- 3'-phosphate 2,1-aminomutase: synthase: [+ 2 isozymes] 3-hydroxyacyl- cyano-7-deazaguanine betB (methylsulfanyl) [sulfur carrier] alanine) pentapeptide a [protein]-S- protein C-methyltransferase: D-ribulose 4(3H)-one nucleotide oxidase ACP dehydratase ethanol glycine betaine 4-aminobutanoate a thymine in DNA C-methyltransferase: form scaffold dxs ACP dehydratase beta-ketoacyl- reductase QueF: queF 37 methyl-L-cysteine NifE: nifE cobA bifunctional AMK03_RS30935 diphosphorylase: ThiO: thiO FabZ: fabZ (S)-ureidoglycolate succinate glyoxylate adenosine NAD + menadiol protein] complex 5-phosphate 1-deoxy-D- a thiocarboxylated- FabZ: fabZ ACP reductase: glycine betaine degradation III F0F1 ATP cobA preQ in tRNA + + [cysteine desulfurase]-S- diaminohydroxyphosphoribosylaminopyrimidine AMK03_RS27645 [+ 3 isozymes] a [TusD sulfur- 1 H H precorrin-2 bifunctional 5-aminolevulinate xylulose 5- [ThiS sulfur- 2-iminoacetate [+ 3 isozymes] AMK03_RS20820 ureidoglycolate synthase sulfanylcysteine:[acceptor deaminase/5-amino-6-(5-phosphoribosylamino) D-erythro-7,8- carrier protein]-S- L-aspartate 4- crotonobetainyl- 4-aminobutanoate a NifEN protein precorrin-2 3,4-dihydroxy- phosphate carrier protein] 3-oxoacyl-[acyl- tRNA guanosine(34) acetyl phosphate lyase: uracil reductase RibD: ribD dihydroneopterin chorismate NaMN a (2E)-but-2-enoyl-[acp] sulfanyl-L-cysteine semialdehyde CoA reductase: 4-aminobutyrate- complex precorrin-2 protein]-cysteine porphobilinogen AIR a (2E)-but-2-enoyl-[acp] transglycosylase Tgt: tgt AMK03_RS16165 a NifB protein precorrin-2 C(20)- 2-butanone- 5-amino-6-(5- carrier-protein] AMK03_RS22860 putrescine degradation I dehydrogenase: sulfurtransferase: nifS dihydroneopterin synthase: hemB nicotinate-nucleotide thiazole synthase: aspartate- acetate/propionate -2-oxoglutarate containing methyltransferase: a [cysteine desulfurase]- 4-phosphate phospho-D- aminodeoxychorismate enoyl-ACP reductase: fabG a 7-aminomethyl-7- predicted cobA aldolase: folB adenylyltransferase: phosphomethylpyrimidine AMK03_RS28725 enoyl-ACP semialdehyde family kinase: glyoxylate transaminase: an L-cluster S-sulfanyl-[disordered- synthase/GTP ribosylamino)uracil synthase component 34 ABC AMK03_RS27715 porphobilinogen reductase FabI: fabI reductase a (3R,11Z)-3-hydroxy- deazaguanosine in tRNA dehydrogenase AMK03_RS17940 AMK03_RS00480 a sugar a sugar form scaffold cyclohydrolase II: bifunctional 6-(hydroxymethyl) I: AMK03_RS18495 AMK03_RS21095 synthase ThiC: thiC superpathway of heme b a [TusE sulfur putrescine succinate transporter sirohydrochlorin 2-[(2R,5Z)- FabI: fabI icos-11-enoyl-[acp] tRNA preQ1(34) S- (non- 6 precorrin-3A protein] complex AMK03_RS24205 diaminohydroxyphosphoribosylaminopyrimidine -7,8-dihydropterin nicotinate adenine biosynthesis from glycine enoyl-ACP a uridine 34 in tRNA carrier protein]-S semialdehyde a ring-opened 7- a [protein]- an O - ditrans,octacis- a [protein]- a DNA methyl a [bis(guanylyl a [glutamine a [protein] N- (4S)-4-hydroxy-2- an N-terminal- an N-terminal- a peptide with a [protein]-L- of a sugar 4-amino-4- hydroxymethylbilane 2-carboxy-4- [+ 2 isozymes] adenosylmethionine phosphorylating): acetate urea degradation II a purine phosphoenol cysteine deaminase/5-amino-6-(5-phosphoribosylamino) superpathway of adenosylcobalamin salvage from cobinamide I dinucleotide HMP-P reductase FabI: fabI 3-hydroxyacyl- -sulfanylcysteine methylguanine adenosylcobinamide L-cysteine methylguanine undecaprenyldiphospho- L-cysteine phosphotriester molybdopterin) cys synthetase]-O terminal-formyl- oxoheptanedioate L-methionyl-L- L-methionyl- an N-terminal methionine 3,4- 2-amino-4-hydroxy-6- deoxychorismate synthase: hemC methylthiazol-5(2H ribosyltransferase- AMK03_RS29175 succinate- dGDP pyruvate dADP precorrin- desulfurase: in DNA ribonucleoside in DNA cofactor 4 -(5'-adenylyl) L-methionine L-methionine peptide- uracil reductase RibD: ribD hydroxymethyldihydropteridine ammonia- NAD+ synthase: gly a butanoyl-[acp] [acyl-carrier- 4-aminobutanal semialdehyde N-acetyl-(N- seryl-[protein] glycyl-[protein] predicted 3B AMK03_RS11275 dihydroxy-2- bifunctional )-ylidene]ethyl a butanoyl-[acp] tRNA 2- isomerase QueA: queA 5'-triphosphate 5-amino-6-(5- protein] urea dehydrogenase: acetylglucosaminyl) chaperone]- -L-tyrosine vitamin B12- methionine ABC cobalt- butanone-4- diphosphokinase: folK preuroporphyrinogen cob(II)inamide dependent AMK03_RS11855 hydroxymethylpyrimidine phosphate 5-aminolevulinate asp 2,4-dihydroxyhept- synthase: [+ 2 isozymes] phospho-D- dehydratase thiouridine(34) 34 urease: ureC gamma- bifunctional helix- muramoyl-L-alanyl-γ- bifunctional helix- L-cysteine dependent (S)-S-oxide a sugar a sugar an S-sulfanyl-[cysteine (7,8-dihydropterin- NAD(+) ammonia- kinase/ beta-ketoacyl- an epoxyqueuosine in tRNA AMK03_RS00475 bifunctional DNA- peptide type I methionyl type I methionyl type I methionyl transporter sirohydrochlorin cobG phosphate ribitylamino)uracil synthase: hemA beta-ketoacyl-ACP synthase AMK03_RS17185 aminobutyraldehyde bifunctional β turn-helix domain- 2-ene-1,7-dioic reductase 6-yl)methyl uroporphyrinogen- cob(I)yrinic acid a,c-diamide synthetase: ACP synthase FabA: fabA formamidopyrimidine turn-helix domain- D-isoglutaminyl-N-( - bifunctional [glutamine deformylase: aminopeptidase: aminopeptidase: aminopeptidase: ribonucleotide of a sugar desulfurase]-S- synthase: 4-aminobenzoate dependent phosphomethylpyrimidine 5-aminolevulinate synthase II: fabF MnmA: mnmA AMK03_RS17195 adenosylcobinamide containing protein/ acid aldolase: pyruvate III synthase: II: fabF tRNA dehydrogenase: succinate containing protein/ D-asparaginyl)-L-lysyl- map reductase: MsrA: msrA precorrin-3B sulfanyl-[disordered- ribB ubiquinol-8 biosynthesis diphosphate adenosyltransferase: cobO nadE NAD(+) kinase: thiD synthase: hemA 3-hydroxyacyl- glycosylase/ kinase/ cysteine synthetase] AMK03_RS02140 AMK03_RS09960 kinase: pyk map map AMK03_RS20265 2-(2-carboxy-4- [+ 2 isozymes] epoxyqueuosine(34) ammonium AMK03_RS19100 methylated-DNA-- D-alanyl-D-alanine methylated-DNA-- AMK03_RS08825 peptide- cob(I)yrinic acid a,c-diamide 5-aminolevulinate [+ 2 isozymes] ACP dehydratase 34 DNA-(apurinic adenylyltransferase/ peptide type I methionyl type I methionyl type I methionyl predicted form scaffold 1-deoxy-L- (early decarboxylation) NAD+ synthase: synthetase: methylthiazol-5- a 2-thiouridine reductase QueG: queG adenosylcobinamide- [protein]-cysteine S- desulfurase 4-hydroxy-2- precorrin-3B C(17)- dihydropteroate HMP-PP FabZ: fabZ or apyrimidinic [protein]-cysteine S- methionine ABC protein] complex glycero-tetrulose all-trans- adenosyltransferase: AMK03_RS11855 nadE a 3-oxohexanoyl-[acp] in tRNA 4-aminobutanoate phosphate methyltransferase: NifS: nifS [glutamine synthetase]- deformylase: aminopeptidase: aminopeptidase: aminopeptidase: class 1b a sugar a sugar cobalt-factor III methyltransferase: [cysteine desulfurase]-S- ARP synthase: folP uroporphyrinogen-III yl)ethyl phosphate a 3-oxohexanoyl-[acp] methyltransferase: oxoheptanedioate (S)-S-oxide 4-phosphate AMK03_RS19665 porphobilinogen a queuosine 34 in tRNA site) lyase: mutM monofunctional adenylyl-L-tyrosine AMK03_RS11125 pyruvate map map map ribonucleoside- transporter octaprenyl + a (2E,11Z)-icosa- guanylyltransferase: AMK03_RS19150 [+ 2 isozymes] aldolase: hpaI AMK03_RS27710 sulfanylcysteine:[acceptor 4-hydroxybenzoate NAD tRNA uridine-5- AMK03_RS19150 phosphorylase: dGTP diphosphate reductase of a sugar diphosphate uroporphyrinogen thiamine phosphate synthase: hemB 3-oxoacyl-[acyl- 2,11-dienoyl-[acp] cobU biosynthetic protein]-cysteine 7,8- [corrinoid adenosyltranferase]-cob(II)inamide 3-oxoacyl-[acyl- carboxymethylaminomethyl(34) methylated-DNA-- AMK03_RS06585 reductase: MsrA: msrA precorrin-4 6,7-dimethyl-8- decarboxylase: synthase: carrier-protein] a [DNA]- a 5'-phospho- 2,6-diamino-4- methylated-DNA-- peptidoglycan a [bis(guanylyl a protein-L- a [cysteine sulfurtransferase: nifS dihydropteroate porphobilinogen carrier-protein] enoyl-ACP synthesis enzyme MnmG: mnmG 4-oxo-2-pentenal adenosyl- [protein]-cysteine S- an N-terminal L- an N-terminal an N-terminal ribityllumazine 4-hydroxybenzoate AMK03_RS00005 reductase: fabG nucleotide- [DNA] hydroxy-5-(N-methyl) [protein]-cysteine S- transglycosylase: molybdopterin) formate pyruvate succinate met met met nrdF nrdE methionine- predicted AMK03_RS28720 reductase: fabG reductase tRNA uridine-5- Carbohydrate Degradation cobinamide methyltransferase: ala methionyl-[protein] L-seryl-[protein] glycyl-[protein] a peptide cobalt-precorrin-3 precorrin-4 C(11)- desulfurase]-(S- synthase: octaprenyltransferase: bifunctional adenosylcobalamin beta-ketoacyl- 3'-phosphate formamidopyrimidine methyltransferase: mtgA cofactor a [glutamine- semialdehyde ADP ABC coproporphyrinogen III [+ 2 isozymes] FabI: fabI phosphate a purine (S)-S-oxide a sugar a sugar methyltransferase: sulfanyl) -[disordered- AMK03_RS04525 folylpolyglutamate salvage from cobalamin hydroxymethylbilane beta-ketoacyl- carboxymethylaminomethyl(34) AMK03_RS01495 AMK03_RS01495 ADP transporter 2 AMK03_RS07685 ACP reductase: Entner-Doudoroff pathway I ribonucleoside chaperone]-S- synthetase]- form scaffold synthase/ synthase: hemC ACP reductase: enoyl-ACP synthesis GTPase MnmE: mnmE (1,4)-β-D-xylan 2-deoxy-D-ribose degradation II of a sugar cobM 6,7-dimethyl-8- oxygen-dependent [corrinoid adenosyltranferase]-cob(I)inamide AMK03_RS20820 D-galactosamine and N- 5'-diphosphate a peptidoglycan di-trans,octa-cis sulfanyl-L-cysteine L-tyrosine protein] complex dihydrofolate thiamine cob(I)alamin AMK03_RS20820 reductase a 5-carboxymethylaminomethyl- protein S-nitrosylation degradation ribityllumazine 4-hydroxy-3- coproporphyrinogen preuroporphyrinogen D-glucopyranose acetyl-D-galactosamine a [protein]-S- dimer (E. faeciums) -undecaprenyl a [protein]-S- precorrin-5 phosphate FabI: fabI 34 2-deoxy-β-D- a guanine in DNA [DNA] octaprenylbenzoate synthase: cob(I)yrinic acid a,c-diamide a (3R)-3-hydroxyhexanoyl-[acp] a (3R)-3- 2-thiouridine in tRNA and denitrosylation degradation methyl-L-cysteine methyl-L-cysteine predicted synthase: a 5,10- oxidase: hemF 6-phosphate a (1->4)-β-D-xylan ribopyranose diphosphate cobalt-precorrin-4 AMK03_RS00125 adenosyltransferase: cobO uroporphyrinogen- hydroxyhexanoyl-[acp] N-acetyl-D- ABC precorrin- AMK03_RS13965 methenyltetrahydrofolate a gondoyl-[acp] a [protein]- glucose-6- endo-1,4-beta- a sugar a sugar 7,8-dihydrofolate protoporphyrinogen IX cob(I)yrinic acid a,c-diamide cob(II)alamin III synthase: 3-hydroxyacyl- galactosamine C1 Compound Utilization and Assimilation transporter cobalt precorrin- 6A synthase a [cysteine desulfurase]- superpathway of pyridoxal 5'-phosphate biosynthesis and salvage 3-hydroxyacyl- L-cysteine phosphate xylanase: a 7,8-dihydro- a methylated an N-terminal- a glucosylated monoglutamate bifunctional AMK03_RS20265 ACP dehydratase 6-phosphate an [HPr]- phosphoenol ditrans,octacis- a nucleoside L-rhamnulose phosphoenol of a sugar 11 (deacetylating): [scaffold protein- 6,7-dimethyl-8-(1- adenosyltransferase: ACP dehydratase 2-oxoglutarate a 3-oxoacid succinyl-CoA a protein with glutathione an N-modified a cytidine 34 4 (C )- methylenetetrahydrofolate protoporphyrinogen thiamine cob(I)yrinic acid a 5-aminomethyl-2- dehydrogenase: β AMK03_RS16755 N-acetylglucosamine- 8-oxoguanine L-histidine pyruvate nucleobase undecaprenyldiphospho- RNA 1-phosphate L-methionyl-L- lys glycogenin AMK03_RS19665 FabZ: fabZ a (1->4)- -D-xylan 2-deoxy-ribono- formaldehyde oxidation aminoacyl-[tRNA] triphosphate dADP pyruvate ATP ATP roseoflavin Ile2 AMK03_RS27730 (2Fe-2S)] complex D-ribityl)lumazine 2-octaprenylphenol FabZ: fabZ 34 a disulfide bond in tRNA 1,4-alpha- methyltransferase: dehydrogenase/ oxidase HemJ: hemJ D-erythrose diphosphate a,c-diamide uroporphyrinogen-III thiouridine in tRNA zwf 6-phosphate formate assimilation into 5,10- formaldehyde oxidation formaldehyde in DNA within DNA N-acetyl-(N- valyl-[protein] biotin predicted [+ 3 isozymes] oligosaccharide 1,5-lactone VII (THF pathway) 5'-phosphate glucan cobM riboflavin synthase: methenyltetrahydrofolate adenosylcobinamide 4-phosphate adenosyltransferase: [+ 3 isozymes] a [protein] 3- glucose-6- deacetylase: nagA methylenetetrahydrofolate II (glutathione-dependent) oxidation IV (thiol- acetylglucosaminyl) ABC precorrin-6A 2-polyprenylphenol uroporphyrinogen 1,4-β-xylosidase: phosphoenolpyruvate- 3-oxoacid CoA- bifunctional branching a sugar a sugar cobalt- AMK03_RS07665 cyclohydrolase FolD: folD protoporphyrin IX cobO fatty acid biosynthesis nitrosothio- independent) bifunctional DNA- alpha-ketoglutarate- muramoyl-L-alanyl- glutathione- DNA-directed type I methionyl tRNA transporter 6-hydroxylase: ubiB a 7,8-dihydrofolate decarboxylase: a (2E)-hex-2-enoyl-[acp] a (2E)-hex-2-enoyl-[acp] phosphate AMK03_RS12300 D-galactosamine formaldehyde -protein transferase aminoacyl- rhamnulose-1- 10 γ protein precorrin-5A a [co-chaperone]- an N - bifunctional initiation (type II) L-alanine dehydrogenase: 6-phosphate formate formaldehyde formamidopyrimidine dependent -D-isoglutaminyl- dependent tRNA RNA polymerase aminopeptidase: biotin--[acetyl-CoA- bifunctional lysidine(34) of a sugar 3-(all-trans cob(I)yrinic acid AMK03_RS00005 a 5-methylaminomethyl- formaldehyde phosphotransferase: ptsP subunit A: phosphate aldolase/ pyruvate GlgB: glgB [scaffold protein- riboflavin formyltetrahydrofolate ferrochelatase: adenosylcobinamide enoyl-ACP AMK03_RS06065 β-D-xylopyranose 2-deoxy- formate-- S-(hydroxymethyl) glycosylase/ dioxygenase AlkB: N-(β-D-asparaginyl) disulfide-bond subunit omega: map carboxylase] ligase: riboflavin kinase/ synthetase -octaprenyl) 4-phospho- a,c-diamide enoyl-ACP 34 formaldehyde AMK03_RS26440 hydrolase: short-chain kinase: pyk (2Fe-2S)] complex AMK03_RS18520 kinase/adenosylcobinamide- 2-thiouridine in tRNA D-ribonate tetrahydrofolate glutathione phosphoenolpyruvate- AMK03_RS23315 -L-lysyl-D-alanine AMK03_RS07030 AMK03_RS08135 FAD synthetase: dihydrofolate D-erythronate adenosyltransferase: coproporphyrinogen III reductase FabI: fabI acetyl-CoA 6-phospho a 5,10- dehydrogenase, DNA-(apurinic oxidoreductase: arfB dehydrogenase: type I methionyl TilS: tilS 1,4-alpha- a sugar RS24065 a sugar SSQ1 bifunctional benzene-1,2-diol phosphate reductase ligase: -protein acyl CoA:acetate/ AMK03_RS04205 precorrin-6B reductase: phosphoribosylglycinamide AMK03_RS19665 enoyl-ACP acetyl-CoA D-glucono- methylenetetrahydrofolate synthase: gfa glutathione- or apyrimidinic alpha-ketoglutarate- yghU [+ 2 isozymes] aminopeptidase: glucan cobalt- chaperone: riboflavin kinase/ bifunctional 2- protoheme erythronate- FabI: fabI S-(hydroxymethyl) phosphotransferase: aminoacyl-tRNA AMK03_RS26915 AMK03_RS13440 guanylyltransferase: cobU oxygen-dependent carboxylase a [protein]- 1,5-lactone D-tagatofuranose 10 AMK03_RS15860 dependent 3-ketoacid CoA branching 15 formyltransferase: cob(II)alamin- reductase FabI: fabI bifunctional an N - independent: fdhA site) lyase: mutM map biotinyl-5'- 34 precorrin-5B precorrin-6B (C ) dnaK FAD synthetase: polyprenyl-6- 4-phosphate [+ 2 isozymes] S-nitrosoglutathione glutathione AMK03_RS13190 monofunctional glutaredoxin hydrolase: pyruvate a lysidine [+ 2 isozymes] AMK03_RS07540 coproporphyrinogen carboxyltransferase a 5-methylaminomethyl- L-cysteine 6-phosphate dioxygenase AlkB: transferase: dATP roseoflavin protein a [chaperone-ATP]- AMK03_RS04205 hydroxyphenol dehydrogenase: [corrinoid 6-phosphogluconolactonase: 2-deoxy- methylenetetrahydrofolate formyltetrahydrofolate formate biosynthetic 3: grxC AMK03_RS15625 adenylate in tRNA Ile2 a sugar RS24225 a sugar methyltransferase: adenosyl-cobinamide phosphate oxidase: hemF a hexanoyl-[acp] subunit beta: 2-(S-geranyl) S-(hydroxymethyl) AMK03_RS00200 AMK03_RS08630 RNA adenine GlgB: glgB [co-chaperone]- methylase/3- AMK03_RS18005 adenosyltranferase] a hexanoyl-[acp] S-(hydroxymethyl) pgl 3-dehydro- dehydrogenase/ bifunctional a [DNA]- peptidoglycan DHAP (S)-lactaldehyde AMK03_RS27700 5,6-dimethylbenzimidazole 34 glutathione a 5'-phospho- 7,8-dihydro- an [HPr protein]- FMN AMK03_RS00120 thiouridine in tRNA methenyltetrahydrofolate 4-oxo-2-pentenal an N-terminal dinucleotide [scaffold protein- demethylubiquinol 3- protoporphyrinogen IX glutathione D-ribonate methylenetetrahydrofolate nucleotide- π transglycosylase: a glycogen a tetrahydrofolate bifunctional (3R)-3-hydroxy-2-oxo- beta-ketoacyl-ACP D-gluconate dehydrogenase/ [DNA] 8-oxoguanine N -phospho- pyruvate a protein with an uncharged met L-valyl-[protein] cobalt- precorrin-7 O-methyltransferase nicotinate-nucleotide-- beta-ketoacyl- malonyl-CoA dehydrogenase/ D-tagatofuranose cyclohydrolase FolD: folD dehydrogenase/ 3'-phosphate a nucleobase mtgA a 2,3,4-saturated GSSG an N-modified (2Fe-2S)] complex bifunctional adenosylcobinamide 4 phosphooxybutanoate 6-phosphate class III alcohol L-histidine formaldehyde succinate succinate reduced L- thiamine phosphate formation from dimethylbenzimidazole synthase II: fabF ACP synthase within DNA 3-oxoacyl-CoA amino acid tRNA a sugar RS15055 a sugar precorrin-6A 5 UbiG: ubiG kinase/adenosylcobinamide- cob(I)alamin- protoporphyrinogen ACP S- class III alcohol glycogen degradation II 1,6-bisphosphate a 5,10- methenyltetrahydrofolate cysteine residues precorrin-7 (C ) riboflavin kinase/ phosphoserine [+ 2 isozymes] phosphogluconate dehydrogenase: formate cobalt-precorrin- SSQ1 2-methoxy- pyrithiamine and oxythiamine (yeast) phosphoribosyltransferase: oxidase HemJ: hemJ II: fabF a 5-methylaminomethyl- dehydrogenase: methenyltetrahydrofolate cyclohydrolase FolD: folD di-trans,octa-cis methyltransferase: FAD synthetase: phosphate transaminase: [corrinoid malonyltransferase: dehydratase: edd AMK03_RS11170 oxidation to CO a peptidoglycan chaperone 6-(all-trans- cobT [+ 2 isozymes] 2-(Se-phospho) AMK03_RS11170 2 6A reductase: AMK03_RS04205 guanylyltransferase: cobU AMK03_RS18010 adenosyltranferase] a 3-oxooctanoyl-[acp] fabD a glycogen D-tagatose- bifunctional a 5,10- dimer (E. faecium -undecaprenyl AMK03_RS27700 pyrithiamine protoporphyrin IX 34 D-glyceroyl-CoA acetoacetate [+ 2 isozymes] AMK03_RS27705 ATPase: dnaK octaprenyl)phenol coenzyme A biosynthesis cob(I)yrinic acid selenouridine in tRNA bisphosphate methenyltetrahydrofolate , tetrapeptide) diphosphate a sugar RS00430 a sugar α 4-phosphooxy- a 3-oxooctanoyl-[acp] S-(hydroxymethyl) KDGP methylenetetrahydrofolate formate precorrin-8x FAD I (prokaryotic) -ribazole 5'-phosphate adenosylcobinamide-GDP a,c-diamide 3-oxoacyl-[acyl- a malonyl-[acp] acetoacetate- glycogen/starch/ aldolase, S-formylglutathione cobalt- thiaminase L-threonine glutathione dehydrogenase/ bifunctional formate a [chaperone- adenosyltransferase: ferrochelatase: carrier-protein] -CoA ligase: alpha-glucan class II, non- precorrin-6B an [2Fe-2S] (R)-4'- dehydrogenase/ methenyltetrahydrofolate dehydrogenase 3 a [protein]-L- precorrin-8X ADP]-[disordered- II: tenA 4-hydroxythreonine- AMK03_RS18520 3-oxoacyl-[acyl- phosphorylase: methylenetetrahydrofolate a single a carboxy- ditrans,octacis- an N -methyladenine a 1-acyl-2- an N-terminal- a peptide with a (1->4)- 2-methoxy-6-all cobO reductase: fabG ketoacyl-ACP a 5-methylaminomethyl- AMK03_RS03765 catalytic subunit: S-formylglutathione 34 4-hydroxy- 5 NADH N-acetyl- cobalt-precorrin- cluster protein phosphopantothenate adenosylcobinamide- carrier-protein] class III alcohol 2-dehydro-3-deoxy- cyclohydrolase FolD: folD dehydrogenase/ subunit alpha: fdhF a 5,10-gly a uridine adenylated- cys undecaprenyldiphospho- arachidonoyl- L-methionyl-L- an N-terminal a tRNA precursor glutamate-O asp α-D-glucan a sugar RS30555 a sugar methylmutase: form scaffold bifunctional 4-amino-2-methyl-5- D-glyceraldehyde 4-phosphate synthase III: 34 AMK03_RS18710 hydrolase: fghA stranded DNA in DNA 15 trans-octaprenyl- 2-selenouridine D-galactose degradation I (Leloir pathway) D-glycerate AMK03_RS23410 10 CO L-threonine L-citrulline 6B (C )- GDP ribazoletransferase: pyruvate cob(I)yrinic acid beta-ketoacyl- dehydrogenase: phosphogluconate methenyltetrahydrofolate 2 methylenetetrahydrofolate in tRNA [ThiS sulfur- sn-glycerol L-proline -methyl-ester 1,4-alpha- AMK03_RS27720 protein] complex phosphopantothenoylcysteine dehydrogenase protoheme reductase: fabG AMK03_RS07720 acetoacetyl-CoA an N - N-acetyl-(N- cysteinyl-[protein] 1,4-benzoquinol pyrimidinemethanol 3-phosphate a,c-diamide ACP reductase: in tRNA AMK03_RS30160 aldolase: α aspartate/ glucan methyltransferase non- decarboxylase/ AMK03_RS12250 beta-ketoacyl- an -limit dextrin formyltetrahydrofolate cyclohydrolase FolD: folD formate carrier protein] acetylglucosaminyl) 3-phosphate CTP thioredoxin bifunctional PdxA: pdxA β glycerate kinase: D-glyceraldehyde exodeoxyribonuclease tyrosine/aromatic NAD(+) [decarboxylating]: hydrogenobyrinate bifunctional adenosyltransferase: AMK03_RS20820 S-(hydroxysulfenamide) AMK03_RS18955 -D-galactopyranose acetyl-CoA C- DHAP γ DNA-3- branching chaperonin phosphopantothenate-- 1-deoxy-D- thiamine diphosphate salvage II ACP reductase: an acetoacetyl-[acp] 4-alpha- formyltetrahydrofolate a 5,10- tRNA uridine-5- muramoyl-L-alanyl- -D- type I methionyl prolyl ribonuclease D: low specificity L- chemotaxis diphosphatase: acetylornithine a sugar RS31165 a sugar AMK03_RS27700 pathway demethylmenaquinone hydroxymethylpyrimidine 4-hydroxythreonine- AMK03_RS19665 AMK03_RS09005 3-phosphate VII large subunit: methyladenine aminotransferase: protein molecular cysteine ligase CoaBC: coaBC AMK03_RS20820 glutathione acetyltransferase: deformylase: purU methylenetetrahydrofolate carboxymethylaminomethyl(34) cysteine isoglutaminyl-L-lysyl- aminopeptidase: aminopeptidase: pip AMK03_RS00490 threonine aldolase: response regulator deacetylase: hydrogenobyrinate methyltransferase/2- (R)-4'- kinase/ adenosylcobalamin 5'-phosphate xylulose-5- 4-phosphate adenosylcob(III) a (3R)-3-hydroxyoctanoyl-[acp] D-glyceraldehyde aldose 1- glucanotransferase: AMK03_RS01445 glycosylase I: phosphatidate AMK03_RS29595 nudC GlgB: glgB chaperone 2-phospho- AMK03_RS02840 (glycyl) -D-alanyl-D-alanine AMK03_RS18575 protein-glutamate argE an oxidized phosphopantothenoyl- phosphate 4-amino-2-methyl-5- pyruvate epimerase: malQ formyltetrahydrofolate synthesis enzyme MnmG: mnmG desulfurase 5 cytidylyltransferase: map prolyl ribonuclease cobalt-precorrin-7 a,c-diamide synthase: methoxy-6-polyprenyl- oxythiamine phosphomethylpyrimidine dehydrogenase alamin-[corrinoid a (3R)-3- tRNA processing 3-phosphate D-glycerate exodeoxyribonuclease AMK03_RS02830 aspartate ATPase: dnaK thioredoxin L-cysteine synthase: dxs pyrimidinemethanol AMK03_RS19255 [+ 2 isozymes] a debranched deformylase: purU tRNA uridine-5- NifS: nifS AMK03_RS28805 type I methionyl aminopeptidase: pip D: rnd methylesterase: reduced β- 1,4-alpha- AMK03_RS12460 1,4-benzoquinol kinase: thiD PdxA: pdxA adenosyltranferase] 3-hydroxyacyl- hydroxyoctanoyl-[acp] type I VII small subunit: DNA-3- transaminase: a sugar RS16650 a sugar bifunctional cobalt- an [Fe-S cluster α [+ 2 isozymes] monofunctional aminopeptidase: AMK03_RS18320 glucan hydrogenobyrinate methylase UbiE: ubiE bifunctional thiaminase 3-amino-1- cob(I)yrinic acid bifunctional ACP dehydratase 3-hydroxyacyl- a polycistronic [+ 2 isozymes] acetyl-CoA -limit dextrin formate carboxymethylaminomethyl(34) AMK03_RS04635 phosphatidate glycolaldehyde AMK03_RS09935 nicotinamide D- biosynthesis HMP-P hydroxylamine glyceraldehyde- methyladenine AMP acetate branching precorrin-7 (C(5))- 6-methoxy-3- phosphopantothenoylcysteine II: tenA 1-deoxy-D-xylulose hydroxyacetone hydroxymethylpyrimidine FabZ: fabZ fatty acid elongation -- saturated synthesis GTPase MnmE: mnmE biosynthetic cytidylyltransferase: map gly oxaloacetate ribonucleotide L-citrulline a,c-diamide chaperone]-ATP a,c-diamide ACP dehydratase tRNA precursor 3-phosphate α-D-galactopyranose glycosylase I: a nucleoside 5'- protein methyltransferase/ thioredoxin- methyl-2-all- decarboxylase/ adenosylcobalamin 5-phosphate 1-phosphate kinase/ glycogen/starch/ glucoamylase: a thiocarboxylated- peptidoglycan AMK03_RS09685 a peptide pro a tRNA α cobaltochelatase 5-(2-hydroxyethyl) bifunctional adenosyltransferase: [+ 3 isozymes] FabZ: fabZ dehydrogenase: AMK03_RS04125 monophosphate MeOH a [protein]- - GlgB: glgB cobalt-precorrin- disulfide trans-octaprenyl- phosphopantothenate-- pyridoxine phosphomethylpyrimidine alpha-glucan AMK03_RS30365 Alcohol Degradation a ribonucleoside a single-stranded transglycosylase: biotin RS04690 biotin subunit CobN: cobN -4-methylthiazole hydroxymethylpyrimidine cobO [+ 3 isozymes] gap a 5-carboxymethylaminomethyluridine 34 AMP ala [ThiS sulfur- an N-terminal L- L-glutamate 6B (C(15))- reductase: cysteine ligase CoaBC: coaBC pyridoxine 5'- kinase: thiD an acetoacetyl-[acp] phosphorylase: a 7,8-dihydrofolate 5'-monophosphate oligodeoxyribonucleotide mtgA starch 1,4-benzoquinol a (2E)-oct-2-enoyl-[acp] in tRNA carrier protein] a CDP-1-acyl- met cysteinyl-[protein] methyltransferase: cobaltochelatase: trxB hydroxyethylthiazole kinase/ pyridoxamine cob(I)yrinic acid lactose degradation II an apurinic site phosphate a (2E)-oct-2-enoyl-[acp] ribonuclease α AMK03_RS18710 D-glucopyranose glycerol and glycerophosphodiester degradation 3-methyladenine 2-arachidonoyl- cobT cobS thiamine diphosphate salvage IV (yeast) 4'-phosphopantetheine phosphomethylpyrimidine pyridoxal a,c-diamide HMP-P a tRNA precursor ammonium 13-DPG -D-galactose within DNA AMK03_RS27700 kinase: thiM synthase: pyridoxal enoyl-ACP D: rnd UDP-α-D-glucose ethanol degradation II glycerol degradation V a peptidoglycan di-trans,octa-cis glycerol a reduced cob(II)yrinate kinase: thiD kinase adenosyltransferase: 1-phosphate α 4-methyl-5-(2- phosphopantothenate biosynthesis I AMK03_RS14395 reductase FabI: fabI enoyl-ACP with a 5' extension α-lactose -D- -undecaprenyl H O c-type pantetheine- PdxY: pdxY kinase AMK03_RS19665 bifunctional 5-(2-hydroxyethyl) ribonuclease D: phosphoglycerate dimer (S. aureus) 2 cobalt-precorrin-8 a,c-diamide thiamine a reduced phosphooxyethyl) and a long 3' trailer glucopyranose glycerol 3-demethylubiquinol-8 HMP-PP PdxY: pdxY enoyl-ACP reductase AMK03_RS00490 kinase: glycerol diphosphate RS18825 cytochrome thioredoxin phosphate hydroxymethylpyrimidine -4-methylthiazole 1-phosphate glucokinase: ethanol an oxidized thiazole 3-methyl-2-oxobutanoate adenosylcobalamin reductase FabI: fabI FabI: fabI AMK03_RS18245 adenylyltransferase: 2-methyladeninyl adenosylcobamide pyridoxamine kinase/ a 3-oxoacyl-[acp] AMK03_RS00895 alcohol O c-type bifunctional 2- pyridoxine 5'-phosphate hydroxyethylthiazole a tRNA precursor with 2 a reduced thiaminase coaD biosynthesis from adenosylcobinamide-GDP pyridoxal phosphomethylpyrimidine [+ 2 isozymes] beta-ketoacyl- 3-phospho- 3'-ketolactose alpha-D-glucose dehydrogenase a DNA containing lipid II (meso (R)-4-hydroxy- 4-hydroxy- an [amino-group cytochrome polyprenyl-6- thiamine phosphate 3-methyl-2-oxobutanoate 5'-phosphate kinase: thiM an octanoyl-[acp] a 5' extension and a purine base 5-amino-4- sn-glycerol a CDP- a reduced c- a [DNA]-3'- a 5'-phospho- (S)-1-pyrroline- II: tenA kinase: thiD ACP reductase: ribonuclease D: D-glycerate AdhP: adhP dihydroxyacetone PRPP carbamoyl nitrite H O 3',5'-ADP 4-methyl-2- 4-methyl-2- γ-L-glutamyl- H O c-type 3'-dephospho- synthase: ribonuclease phosphate-specific lesion in DNA diacylglycerol an apurinic/ diaminopimelate L-ornithine 2 hydroxyl [DNA] 5-carboxylate gly carrier protein]- 2 hydroxyphenol hydroxymethyltransferase: 4-methyl-5-(2- an octanoyl-[acp] a short 3' extension beta-glucosidase: a glycerophosphodiester glycerol imidazolecarboxyamide 3-phosphate type cytochrome GTP cytochrome cytochrome cobyrinate 2-methyladenine AMK03_RS20820 AMK03_RS00490 acetaldehyde apyrimidinic site containing) phosphate trifunctional oxoglutarate oxoglutarate D-alanine C-terminal-γ- an oxidized methylase/3- CoA AMK03_RS28720 AMK03_RS27665 pyridoxamine pyridoxamine pyridoxal phosphooxyethyl) beta-ketoacyl-ACP D: rnd 2,3-bisphosphoglycerate- AMK03_RS18980 phosphoglucomutase: 3'(2'),5'-bisphosphate 4-carboxy-4- 4-carboxy-4- c oxidase 4-amino-2-methyl-5- 5-(2-hydroxyethyl) HMP-PP ribonuclease melibiose degradation dihydroxyacetone kinase demethylubiquinol 3- dephospho- [+ 2 isozymes] 5'-phosphate 5'-phosphate kinase thiazole synthase II: fabF 3-oxoacyl- ribonuclease D: dependent AMK03_RS18730 nucleotidase CysQ: transcriptional (L-glutamate 5- O c-type cobyrinate A,C- 3-methyl-2-oxobutanoate nicotinate-nucleotide-- ribonuclease P 3-keto-β-D- acetaldehyde subunit DhaK: dhaK adenine cisplatin damage hydroxy-2- hydroxy-2- 2 pyrimidinemethanol -4-methylthiazole beta- [acyl-carrier- D: rnd glycerophosphodiester glycerol kinase bifunctional DNA- regulator/proline semialdehyde-2-N-acetyl- cytochromea reduced O-methyltransferase CoA kinase: hydroxymethyltransferase: oxidase: pdxH oxidase: pdxH PdxY: pdxY [+ 2 isozymes] AMK03_RS00490 phosphoglycerate dehydrogenase: CDP-diacylglycerol-- endonuclease monofunctional ornithine nitrite AMK03_RS04260 oxoadipate oxoadipate glutathione diamide synthase: dimethylbenzimidazole ketoacyl- protein component: galactose phosphodiesterase: GlpK: glpK PTS-dependent formamidopyrimidine phosphoribosyltransferase: GTPase response ATP- gamma- H O c-type bifunctional hydroxyethylthiazole AMK03_RS00025 protein] mutase: melibiose glycerol-3-phosphate 3- dehydrogenase/L- synthase: yl)-L-glutamate 2 cytochrome- AMK03_RS12460 UbiG: ubiG thiamine panB phosphoribosyltransferase: thiamine phosphate AMK03_RS02250 UDP-glucose AMK03_RS21000 AMK03_RS25350 III: nth biosynthetic carbamoyltransferase: reductase, HflX: hflX dependent 3'(2'),5'-bisphosphate aldolase/ aldolase/ ACP reductase: ribonuclease AMK03_RS09625 glycerol kinase dihydroxyacetone kinase glycosylase/ glutamate gamma- glutamyl- c oxidase, cytochrome hydroxymethylpyrimidine kinase: thiM phosphate cobT synthase: a 3-oxodecanoyl-[acp] AMK03_RS00880 4-epimerase D-xylose phosphatidyltransferase: peptidoglycan AMK03_RS10145 copper- nucleotidase oxaloacetate oxaloacetate gshB an oxidized cob(II)yrinate coenzyme A PLP synthase PH: rph D-glucopyranose GlpK: glpK phosphotransferase: DNA-(apurinic adenine bifunctional DNA- [+ 5 isozymes] DNA ligase: phosphate kinase/ 4-methyl-5-(2- ubiquinol-8 2-dehydropantoate AMK03_RS28720 fabG GalE: galE degradation I [+ 4 isozymes] acetate pgsA transglycosylase: containing: CysQ: cysQ semialdehyde O cbb3-type c-type I: fabB 2,3-bisphosphoglycerate- alpha-glucosidase/ AMK03_RS13180 dhaK or apyrimidinic formamidopyrimidine ornithine AMK03_RS05960 decarboxylase: decarboxylase: an [amino-group 2 a,c-diamide phosphomethylpyrimidine 3-oxoacyl-[acyl- a (3R)-3- polyribonucleotide 6-phosphate phosphoribosyltransferase: dehydrogenase: reductase: a reduced phosphooxyethyl) folate transformations III (E. coli) [+ 2 isozymes] a 2,3,4-saturated a tRNA precursor a tRNA precursor with dependent α [+ 2 isozymes] D-galactopyranose mtgA carbamoyltransferase: nirK AMK03_RS23175 AMK03_RS23175 cytochrome 2-dehydropantoate 2-methyladenine nucleotidyltransferase: pnp -D-glucopyranose alpha-galactosidase: site) lyase: mutM AMK03_RS15660 glycosylase/ + carrier protein]-argC kinase: thiD thiazole carrier-protein] [+ 2 isozymes] hydroxyacyl-[acyl- a short 3' extension UDP-α-D-galactose D-xylose acetate--CoA 1-(3-sn- phosphate H AMP putA norophthalmate H O cytochrome- c-type adenosylcobinamide- ribotide phosphate fatty acyl-[acp] with a 5' extension phosphoglycerate 1-phosphate AMK03_RS25910 sn-glycerol 3-phosphate DHAP CMP DNA-(apurinic argF GDP pyruvate pyruvate C-terminal-γ- 2 2-reductase: reductase: fabG beta-hydroxyacyl-carrier protein] xylose ligase: acs phosphatidyl) c oxidase, cytochrome thiamine phosphate GDP a tetrahydrofolate thiamine mutase: or apyrimidinic lipid II (meso di-trans,octa-cis [DNA] glu (5-phospho- an oxidized HMP-P NAD salvage pathway I (PNC VI cycle) AMK03_RS08590 ACP dehydratase: isomerase: alpha-glucosidase/ a [DNA]- a 5'-phospho- a modified -sn-glycerol an oxidized c- synthase: phosphate beta-ketoacyl- ribonuclease D: AMK03_RS24215 alpha-D-glucose site) lyase: mutM diaminopimelate -undecaprenyl nitric oxide O cbb3-type c-type adeninyl adenosylcobamide biosynthesis alpha-galactosidase: glycerol-3-phosphate acetyl-CoA nucleotide- 4-oxo-2-pentenal AICAR L-glutamyl)- 2 bis(guanylyl molybdopterin) β-alanine ACP reductase: AMK03_RS12425 ribonuclease P ribonuclease xylA [DNA] nucleobase 3-phosphate type cytochrome a reduced bifunctional AMK03_RS28720 (R)-pantoate adenosylcobinamide- AMK03_RS00490 phosphate-specific dehydrogenase: glpD containing) diphosphate L-glutamate cytochrome cofactor sulfurylation from adenosylcobinamide-GDP + methionine protein component: 2-phospho- AMK03_RS25935 3'-phosphate L-citrulline [+ 2 isozymes] NAD AMK03_RS20820 [+ 3 isozymes] PH: rph D-xylulose H O c-type hydroxymethylpyrimidine GDP ribonuclease D-glycerate phosphoglucomutase: 2 synthase: AMK03_RS02250 a 3'-terminal a 5'-phospho- cytochrome cytochrome kinase/ thiamine ribazoletransferase: D: rnd AMK03_RS18730 xylulokinase: DHAP an oxidized cys ammonia-dependent pantoate--beta-alanine dihydrofolate metH a (3R)-3-hydroxydecanoyl-[acp] phosphopyruvate D-galactopyranose D-glucopyranose unsaturated sugar [DNA] c oxidase phosphomethylpyrimidine phosphate adenine NAD(+) synthetase: nadE AMK03_RS12250 reductase: thiamine xylB O c-type ligase: AMK03_RS27755 hydratase: eno D-glucopyranose 2 kinase: thiD diphosphate acytochrome reduced cysteine NAD+ synthase: AMK03_RS13440 3-hydroxyacyl- 6-phosphate D-xylulose nicotinate-nucleotide-- NAD+ synthase: NAD(+) Coα-[α-(2- serine acyl-CoA/acyl-ACP phosphoenol a reduced (2S)- H O c-type AMK03_RS11855 [+ 2 isozymes] a trans-2- a mature peptidoglycan (meso sn-glycero-3- a peptide with a supercoiled 2 desulfurase: HMP-PP AMK03_RS11855 ACP dehydratase a 2,3,4-saturated 5-phosphate ubiquinone-6 acetoacetate succinyl-CoA NADPH NAD + a uracil in DNA MoO - oxaloacetate L-cysteate carbonic acid cytochrome dimethylbenzimidazole diphosphatase: nudC (R)-pantothenate methyladenin-9-yl)]-Co a 7,8-dihydrofolatehydroxymethyltransferase:a 5-methyltetrahydrofolate dehydrogenase: enoyl-[acyl- lipoprotein posttranslational modification pyruvate -diaminopimelate containing) electron-transfer phospho-N- methylsuccinyl- 2 an N-terminal duplex DNA cytochrome AMK03_RS11275 glycine cleavage system FabZ: fabZ dGTP acetyl-CoA ATP IMP c oxidase an oxidized phosphoribosyltransferase: ammonia-dependent β-adenosylcobamide benzimidazolyl adenosylcobamide AMK03_RS07650 fatty acyl-[acp] AMK03_RS20945 flavoprotein (arachidonoyl) CoA molybdopterin citrate synthase: aspartate/ L-alanine ATP- thiamine carrier protein] pyruvate O c-type [+ 2 isozymes] NAD(+) synthetase: nadE type I pantothenate aminomethyltransferase [+ 3 isozymes] an uncharged tRNA a [prolipoprotein]- Carboxylate Degradation cofactor AMK03_RS10940 5'/3'-nucleotidase 2 cobT 5'-phosphate biosynthesis from adenosylcobinamide-GDP thymidylate a (6S)-5- [+ 2 isozymes] kinase: pyk ethanolamine tyrosine/aromatic dependent a metal a metalcytochrome an [L-cysteine nicotinate adenine dinucleotide NMN kinase: AMK03_RS00205 GcvT: gcvT lytic transglycosylase acyl CoA:acetate/ NAD(P)(+) uracil-DNA carbonic SurE: surE RS17450 thiamine synthase: bifunctional formyltetrahydrofolate L-cysteine electron transfer 3-oxoadipyl- citrate synthase/ aminotransferase: DNA cation cation desulfurase]-S- a (2E)-dec-2-enoyl-[acp] domain-containing 3-ketoacid CoA glycosylase: anhydrase: aminopeptidase adenine ribotide benzimidazole AMK03_RS14550 methylenetetrahydrofolate 5-formyltetrahydrofolate prolipoprotein pyruvate pyruvate decarboxylation to acetyl CoA I deoxyguanosinetriphosphate flavoprotein- transhydrogenase molybdenum cofactor methylcitrate AMK03_RS29595 pyrimidine 5'- helicase sulfanyl-L-cysteine thiamine diphosphate diphosphokinase: (R)-4'-phosphopantothenate glycolate and protein: glycerophosphodiester CoA adenosylcobinamide- phosphate dehydrogenase/ enoyl-ACP Detoxification propanoyl CoA acetate triphosphohydrolase: ubiquinone transferase: (Re/Si-specific): AMK03_RS06615 guanylyltransferase: synthase: AMK03_RS21265 N: pepN nucleotidase: RecG: recG cysteine biosynthesis III AMK03_RS20875 nicotinate-nucleotide Coα-[α-(2- cyclo-ligase: enoyl-ACP diacylglyceryl glyoxylate AMK03_RS14865 phosphodiesterase: thiolase: aspartate bis(guanylyl GDP nicotinate-nucleotide-- methylenetetrahydrofolate methenyltetrahydrofolate reductase a [pyruvate degradation I conversion AMK03_RS09135 oxidoreductase: AMK03_RS08630 AMK03_RS18810 uracil-DNA mobA AMK03_RS10945 [+ 2 isozymes] AMK03_RS02190 a metal a metal desulfurase: (Staphylococcus) adenylyltransferase: methyladenin-7-yl)]-Co AMK03_RS18085 reductase FabI: fabI CDP-diacylglycerol transferase: AMK03_RS05945 pcaF 1,2- transaminase: DNA RS17655 thiamine dimethylbenzimidazole reductase [NAD(P)H]: metF FabI: fabI dehydrogenase degradation II to acetyl-CoA [+ 10 isozymes] AMK03_RS06645 AMK03_RS18815 glycosylase: AMK03_RS11275 molybdopterin) 2-(2-carboxy-4- AMK03_RS21095 β-adenosylcobamide a 5,10- cyclohydrolase FolD: folD a 5,10- biosynthesis I AMK03_RS15575 arsenate reactive oxygen species degradation pyruvate 3-oxoacid CoA- AMK03_RS09935 inosine helicase cation cation diphosphate adenosylcobinamide- phosphoribosyltransferase: enoyl-ACP arsenate 8-oxo-(d)GTP detoxification I E2 protein] N 6 propanoyl-CoA [+ 4 isozymes] AMK03_RS18820 ung dihydroxypropane- cofactor methylthiazol-5- methylenetetrahydrofolate methenyltetrahydrofolate enoyl-ACP a [prolipoprotein]- detoxification glycolate acetate transferase adenylyl ala a peptide RecQ: [+ 2 isozymes] HMP-PP cobT reductase FabI: fabI detoxification -lipoyl-L-lysine acyl-CoA a mature peptidoglycan a mature peptidoglycan strand 4-methyl-3- 1,2,3-tricarboxylate 3-sulfopyruvate CO H O GDP DHAP reductase S-1,2-diacyl-sn- pyruvate glycolate an oxidized subunit A: [+ 3 isozymes] 2 2 yl)ethyl phosphate II (glutaredoxin) acetate- triphosphate + molybdenum recQ a [bis(guanylyl 5-methylbenzimidazolyl adenosylcobamide benzimidazole bifunctional superoxide carboxylase with (L-alanyl-γ-D-glutamyl- 2'-deoxyguanosine H ubiquinol-6 ribazoletransferase: NaMN nicotinamide glycerol-3- FabI: fabI glyceryl-L-cysteine III (thioredoxin) dihydrolipoyl dehydrogenase: oxidase: glcE glcF -CoA (non-reducing terminus) electron-transfer AMK03_RS26440 sn-glycerol oxoadipyl-CoA cofactor a single a metal a metal molybdopterin) biosynthesis from adenosylcobinamide-GDP adenosylcobinamide- ribotide methylenetetrahydrofolate thiamine diphosphate a decanoyl-[acyl-carrier protein] arsenate subunit beta: meso-2,6-diaminopimeloyl- anandamide an apyrimidinic uracil RS17780 thiamine phosphate AMK03_RS12250 phosphate arsenate dGTP GTP dehydrogenase: pdhA glyoxylate ligase: acs flavoprotein 3-phosphate stranded DNA cation cation cofactor [bis-MGD cofactor GDP dehydrogenase/ biosynthesis I (E. coli) site in DNA phosphate signal peptidase II: arsenate reductase AMK03_RS20140 AMK03_RS09765 AMK03_RS11195 D-alanine) tetrapeptide NADH NADP + chaperone]-S- chaperone]- synthase: heme b biosynthesis II α α 5-methylbenzimidazole beta-ketoacyl-ACP dehydrogenase: arsenate (S)-methylmalonyl- acetyl-CoA Co -[ -(adenin-9-yl)]- molybdopterin biosynthesis methenyltetrahydrofolate 2-[(2R,5Z)- AMK03_RS02040 (glutaredoxin): arsC acetoacetyl-CoA succinate sulfanyl-L-cysteine bis-MGD AMK03_RS28720 (oxygen-independent) β synthase II: fabF AMK03_RS20250 reductase [+ 2 isozymes] CoA malate synthase G: Co -adenosylcobamide adenosylcobinamide- cyclohydrolase FolD: folD 2-carboxy-4- sn-glycerol arsenate a [pyruvate pyruvate a [pyruvate [+ 2 isozymes] bifunctional nicotinamidase/ nicotinate-nucleotide-- hydrogen (glutaredoxin) 8-oxo-dGTP 8-oxo-GTP methylmalonyl- AMK03_RS00270 a metal a metal 5'-phosphate nicotinate GDP 10 [+ 2 isozymes] an (S-diacyl-sn- dehydrogenase dehydrogenase RS04250 dipyrromethane dimethylbenzimidazole an N - methylthiazol-5(2H 3-phosphate biotin-carboxyl carrier protein assembly a lipoprotein reductase ArsC: peroxide dehydrogenase cation cation uroporphyrinogen-III pyrazinamidase: pncA : arsC 6 6 CoA D-gluconate phosphoribosyltransferase: ribazoletransferase: )-ylidene]ethyl glyceryl)-L-cysteinyl- AMK03_RS13090 E2 protein] N E2 protein] N -S- uroporphyrinogen cofactor biosynthesis phosphoribosyltransferase: ATP formyltetrahydrofolate HMP-PP a 3-oxododecanoyl-[acp] glycerol-3- signal peptide arsenite 8-oxo-dGTP complex (S)-malate a nascent peptidoglycan an N-formyl-L- a peptidoglycan (2R,3S)-3- thiamine epimerase: mce degradation a [DNA]-3'- + a 5'-phospho- + + β an L-cysteinyl- pncB AMK03_RS12250 phosphate a [biotin carboxyl- [apolipoprotein] arsenite diphosphatase -dihydrolipoyl- dihydrolipoamideacetyldihydrolipoyl- a 5-L-glutamyl- NAD 5'-deoxyadenosine malonyl-CoA H ammonium NAD H O 1-butanesulfonate -citryl-L- acetyl-CoA cobT phosphate signal peptide catalase/ (meso-DAP containing) an amino acid methionylaminoacyl- dimer (generic) 2 isopropylmalate sarcosine met Pro sulfo-bis(guanylyl phosphate decarboxylase: an apo-[hydroxymethylbilane cys GTP L-lysine (R)-methylmalonyl- hydroxyl [DNA] glutamine [tRNA ] nicotinate molybdopterin- carrier protein]-L-lysine apolipoprotein N- MutT: mutT L-lysine acetyltransferase: [peptide] acetyl-CoA a metal a metal molybdopterin) AMK03_RS00005 Coα-[α-(adenin-7-yl)]- Coα-[α- 3-oxoacyl-[acyl- acyltransferase: peptidase peroxidase D-gluconate tRNA 3-isopropylmalate bifunctional RS19615 synthase]-L-cysteine adenosylcobinamide- 5-methylbenzimidazole thiamine phosphate biotin--[acetyl-CoA- acyltransferase: lnt AMK03_RS09770 CoA cation cation cofactor coproporphyrinogen III Coβ-adenosylcobamide synthase cysteine carrier-protein] AMK03_RS04835 SppA: sppA HPI: katG 8-oxo-GMP gluconokinase: dehydratase carboxylase GDP ribotide phosphate (benzimidazolyl)]-Co GTP 3',8- synthase: carboxylase] ligase: H O hydroxyl radical 8-oxo-dGMP methylmalonyl- lytic transglycosylase DNA 5'-methylthioadenosine/ lytic type III polyketide nitrite FMNH2-dependent glutamate N- β adenylyltransferase desulfurase: NAD reductase: fabG an N-acyl-(S-diacyl- 2 AMK03_RS22950 small subunit: leuD biotin S-adenosyl-L- -adenosylcobamide cyclase glycerol-3- CoA domain-containing gamma- peptide S-adenosylhomocysteine transglycosylase synthase: reductase alkanesulfonate glycine oxidase N-formylglutamate acetyltransferase/ Cys- coproporphyrinogen a [hydroxymethylbilane MoeB: AMK03_RS11275 AMK03_RS28720 AMK03_RS08135 sn-glyceryl)-L- a peptide arsenite ligase carboxylase methionine salvage II 5'-phosphate MoaA: moaA phosphorylation and beta-ketoacyl- phosphate 1-O- arsenite O mutase: scpA gluconokinase: protein: glutamyltransferase: ggt deformylase: nucleosidase: domain-containing small subunit monooxygenase: 3-isopropylmalate amino-acid tRNA(Pro) thiamine dehydrogenase: synthase] ES intermediate adenosylcobinamide- AMK03_RS00735 [+ 2 isozymes] a [biotin carboxyl-carrier cysteinyl-[lipoprotein] 2 D: ligD AMK03_RS23680 ThiO: thiO deformylase: hutG subunit: accC a metal a metal 2 molybdenum cofactor biosynthesis [+ 2 isozymes] (8S)-3',8-cyclo-7,8- transhydrogenation ACP reductase: acyltransferase AMK03_RS03840 AMK03_RS14865 gamma- AMK03_RS02140 AMK03_RS01555 protein: NirD: nirD ssuD dehydratase acetyltransferase deacylase: RS28235 AMK03_RS24985 GDP a carboxy-adenylated an [L-cysteine protein]-N 6 -biotinyl-L-lysine D-gluconate [+ 2 isozymes] type III polyketide cation cation hydroxymethylbilane dihydroguanosine + AMK03_RS20820 succinyl-CoA large subunit: leuC [+ 6 isozymes] ybaK di-trans,poly-cis thiamine SAH NAD PlsY: plsY acetyl-CoA [+ 10 isozymes] glutamyltransferase: ggt peptide AMK03_RS14865 ArgJ: argJ [+ 2 isozymes] ribazoletransferase: [small subunit of desulfurase]-S- thiamine 6-phosphate synthase: (2S)-2- N-acetyl-L- diphosphokinase: synthase: hemC 5'-triphosphate a 1-acyl-sn deformylase: malonyl-CoA -undecaprenyl adenosylhomocysteinase: molybdate AMK03_RS12250 Coα-[α- molybdopterin synthase] sulfanyl-L-cysteine NAD kinase: phosphate [+ 11 isozymes] AMK03_RS03855 isopropylmalate glyoxylate methylamine citrate AMK03_RS20875 folate polyglutamylation cyclic pyranopterin a (3R)-3-hydroxydodecanoyl-[acp] -glycerol 3- α 5-deoxy-D-ribose gln methionine phosphate biosynthesis protoporphyrinogen IX a [hydroxymethylbilane (benzimidazolyl)]-Co AMK03_RS08295 5,6-dimethylbenzimidazole 5-oxo-L-proline metabolism a mature peptidoglycan a nascent peptidoglycan an -(5-L- [DNA] NMN AMK03_RS11125 nitrite 1-butanal sulfite a metal a metal AMK03_RS00160 monophosphate phosphate adenine Pro RS12790 synthase] ES intermediate Coα-[α-(5- β + a [biotin carboxyl- Nucleoside and Nucleotide Degradation γ glutamyl)- AMP cys a tRNA (2E,6E)-farnesyl thiamine glutathione- 3 predicted ABC -adenosylcobamide NADP biosynthesis I (aerobic) with (L-alanyl- -D-glutamyl- (meso-DAP containing) a peptide GlcNAc-1,6- cation cation IPP L-homocysteine molybdopterin synthase 3-hydroxyacyl- 1-acyl-sn-glycerol- carrier-protein dimer]- a [protein] with amino acid a lipid II diphosphate diphosphate glutaredoxin hydroxymethylbilane transporter methylbenzimidazolyl)]- a tetrahydrofolate a [protein] with meso-2,6-diaminopimeloyl- with GlcNAc terminus anhydro-MurNAc- octoketide β MoaC: moaC NAD(P) ACP dehydratase 3-phosphate N 6 -biotinyl-L-lysine an N-terminal formate a L-methionylaminoacyl- synthase: hemC molybdopterin of molybdate: Co -adenosylcobamide a thiocarboxylated riboflavin an N-terminal purine nucleotides degradation II (aerobic) superpathway of purine deoxyribonucleosides degradation D-alanine) tetrapeptide pentapeptide redox reactions methionine thiamine FabZ: fabZ acyltransferase: superpathway of pyrimidine tRNA isoprenyl adenylyltransferase: modA modB 5'-phosphate [small subunit of cyclic pyranopterin transhydrogenase bifunctional riboflavin acetyl-CoA L-glutamine L-glutamate a metal a metal protoporphyrin IX glutathione a [hydroxymethylbilane synthase: metH bifunctional serine formate-- diphosphate [+ 3 isozymes] AMK03_RS28810 deoxyribonucleosides degradation RS29640 transferase: [+ 2 isozymes] molybdopterin synthase] phosphate subunit alpha: kinase/FAD synthetase: carboxylase biotin cation cation synthase] ES intermediate AMK03_RS10910 folylpolyglutamate hydroxymethyltransferase: tetrahydrofolate [+ 2 isozymes] acetyl-CoA AMK03_RS09680 4 AMK03_RS18815 AMK03_RS04205 carboxylase subunit: AMP 2'-deoxycytidine menaquinol-7 biosynthesis ferrochelatase: molybdopterin AMK03_RS07650 ligase: a (2E)-dodec-2-enoyl-[acp] a 1,2-diacyl- carboxylase 2'-deoxyguanosine 34 a 2,3,4-saturated an sn-glycero-3- DNA with adenine:7,8- (4Z)-2-oxohept- hydroxymethylbilane met molybdate synthase/ FMN AMK03_RS23235 a 5,10- a 2-thiouridine pyruvate β-citryl-L- Coα-[α-(5- NAD(P) sn-glycerol MoO - 1,2-diacyl-sn- phospho-N-(acyl) SAH dihydro-8- asp O-ureido-L- γ-L-glutamyl-(S)- gly L-quinate 3'-AMP RNA sec AMK03_RS18520 a reduced adenine dinucleotide dihydrofolate AMK03_RS15860 carboxyltransferase methylenetetrahydrofolate in tRNA 2 GTP 4-enedioate ser a tRNA di-trans,octa-cis synthase: hemC methylbenzimidazolyl)]- acetyl-CoA a [protein] with 5'/3'-nucleotidase nucleoside 2'-deoxyadenosine molybdopterin CTP homoserine 2-aminobutanoate glutamate a metal a metal all-trans- synthase: a 5,10- transhydrogenase flavin reductase: enoyl-ACP 3-phosphate subunit beta: γ-L-glutamyl molybdopterin glycerol 3-phosphate ethanolamine oxoguanine mismatch glucose/quinate/ bifunctional 2',3'- 2-oxo-hepta- RS24675 -undecaprenyl glutaredoxin methionine β an N-terminal 5- cation cation heptaprenyl 1,4-dihydroxy- Co -adenosylcobamide 10 subunit alpha: reductase FabI: fabI carboxylase glutathione SurE: surE deaminase: cofactor 3-ene-1,7- protoheme a holo-[hydroxymethylbilane adenosyltransferase: molybdopterin AMK03_RS00125 methylenetetrahydrofolate an N - AMK03_RS11370 phosphatidate AMK03_RS00120 5-phosphate shikimate family cyclic-nucleotide 2'- diphosphate 2-naphthoate glutathione- molybdopterin menaquinol-9 biosynthesis biotin carboxylase oxo-L-proline AMK03_RS09995 purine-nucleoside tRNA uridine-5- pyruvate, diphosphate synthase] molybdotransferase AMK03_RS25160 enoyl-ACP cytidylyltransferase: pyrimidine 5'- thymidine phosphatidate 5'-methylthioadenosine/ A/G-specific argininosuccinate glutathione membrane-bound phosphodiesterase/ ribonuclease dioic acid undecaprenyl- AMK03_RS01920 bifunctional formyltetrahydrofolate [+ 2 isozymes] phosphorylase: carboxymethylaminomethyl(34) phosphate glycerophosphodiester N-formylglutamate serine- dependent reductase FabI: fabI AMK03_RS09685 subunit: accC nucleotidase: [+ 2 isozymes] adenosine molybdenum cofactor cytidylyltransferase: synthase: synthase: PQQ-dependent 3'-nucleotidase: PH: rph hydratase: diphosphate MoeA: folylpolyglutamate bifunctional NADPH thymidine dikinase: phosphodiesterase: S-adenosylhomocysteine adenine -tRNA a metal a metal disulfide-bond a tetrahydrofolate glutathione demethylmenaquinol-9 FMNH a [carboxyl-carrier AMK03_RS02190 IMP deaminase: AMK03_RS00995 synthesis enzyme MnmG: mnmG guanylyltransferase: deformylase: hutG hpaH RS00545 SAM AMK03_RS10910 2 phosphatidate purine-nucleoside AMK03_RS28805 AMK03_RS09625 nucleosidase: glycosylase: AMK03_RS20345 gshB dehydrogenase: AMK03_RS08890 ligase: phosphatase: oxidoreductase: synthase/ folylpolyglutamate biosynthesis protein dimer]-N 6 - 2'-deoxyuridine phosphorylase: AMK03_RS01020 tRNA uridine-5- AMK03_RS05055 (4S)-4-hydroxy-2- cation cation bis(guanylyl molybdenum bifunctional a dodecanoyl-[acp] cytidylyltransferase: GMP mobA AMK03_RS01555 mutY AMK03_RS06250 serS AMK03_RS01615 dihydrofolate synthase/ carboxybiotinyl-L-lysine deoA phosphorylase: phosphatidate [+ 4 isozymes] oxoheptanedioate cytidylyl molybdenum yghU cofactor) biosynthesis demethylmenaquinone 5,6-dimethylbenzimidazole 5-oxo-L-proline adenosine IMP carboxymethylaminomethyl(34) adenosine a nucleoside RNA di-trans,octa-cis demethylmenaquinol-7 glutathione- guanylyl molybdenum MoO -molybdopterin cofactor synthase: dihydrofolate AMK03_RS28805 AMK03_RS00995 purine-nucleoside cytidylyltransferase: 3-dehydroquinate cofactor sulfurylation glutaredoxin 2 cys glu methyltransferase/2- synthase: bluB 5'/3'-nucleotidase dehydrogenase: thymine synthesis GTPase MnmE: mnmE phosphoenol citrate diphosphate -undecaprenyl cofactor biosynthesis MoO - + bis(guanylyl AMK03_RS09685 canavaninosuccinate ophthalmate glu peroxide 2 AMK03_RS00125 synthase: a CDP- 5-oxoprolinase phosphorylase: diphosphate H an apurinic site a metal a metal 3: grxC molybdopterin bis(guanylyl tungstenpterin) methoxy-6-polyprenyl- beta-ketoacyl-ACP adenosine SurE: surE guaB 2'-deoxyinosine AMP pyruvate molybdopterin) sn-glycerol an N- S-ribosyl-L- an L-seryl- EmfA phosphate bifunctional cytidylyl molybdenum redox reactions MoO - molybdopterin AMK03_RS00125 5,6-dimethylbenzimidazole diacylglycerol uracil AMK03_RS00995 cation cation a protein with 2 a 5,10- synthase II: fabF subunit acylethanolamine adenine adenine within DNA sec demethylmenaquinone cofactor (trioxo) molybdopterin cofactor lipoate biosynthesis cofactor biosynthesis 1,4-benzoquinol deaminase: pyrimidine 5'- phosphorylase: UTP and CTP dephosphorylation I a 5-aminomethyl-2- cofactor 3-phosphate homocysteine [tRNA ] reduced L- GSSG menaquinol-8 biosynthesis and incorporation I methylenetetrahydrofolate an N 10 - glutamate-- methylase UbiE: ubiE [+ 2 isozymes] PxpB: pxpB XMP 2-deoxy-α-D- a 7,8-dihydrofolate a CDP-2,3,4-saturated- methyltransferase/2- cofactor AMK03_RS01020 nucleotidase: deoA thiouridine 34 in tRNA molybdopterin- formyltetrahydrofolate cysteine ligase: laurate cysteine residues molybdenum cofactor menaquinol-9 (Kdo) -lipid A ribose 1-phosphate diacylglycerol 2+ methoxy-6-polyprenyl- base-degraded 2 AMK03_RS02190 UTP Mg Mg 2+ an [MCD cofactor guanine AMK03_RS04065 GTP glu ApaG demethylmenaquinol-8 guanylyltransferase: an octanoyl-[acp] bis(tungstenpterin) long-chain fatty biosynthesis I (E. coli) inosine 5'/3'-nucleotidase 2+ 2+ 1,4-benzoquinol chaperone]-MCD dinucleotide thiamine salvage menaquinol-6 biosynthesis a 3-oxotetradecanoyl-[acp] phosphopentomutase: Co Co thiamine bifunctional mobA cofactor α α SurE: surE methylase UbiE: ubiE glutathione- lipoyl(octanoyl) acid--CoA ligase: -Kdo-(2->4)- -Kdo- guanosine α AMK03_RS01025 nucleoside CTP synthase: 2-hydroxy-4-oxobutane- N-acetyl-β-D- 6-O-trans- diphosphate cysteine biosynthesis formylaminopyrimidine γ-L-glutamyl- uracil 2-deoxy- -D- 3-methyl-2- 5,10-methylene- a peptidoglycan chitin disulfide demethylmenaquinone transferase AMK03_RS02460 CDP-diacylglycerol (2->6)-lipid IV (E. coli) purine-nucleoside pyrimidine 5'- triphosphate AMK03_RS10950 a lipid II glutathione glu a (6S)-5- an alkylated DNA a RNA-DNA hybrid L-quinate 3'-GMP glu ala N-ethylglycine methoxy-mycolyl- a protein protein B: mobB 3-oxoacyl-[acyl- lipidA A biosynthesis ribose 1-phosphate 2-deoxy-D-ribose oxobutanoate tetrahydromethanopterin hypoglycin A 1,2,4-tricarboxylate glucosaminyl-(1 salvage III menaquinol-7 desulfurase: acyl carrier methyltransferase/2- bis(molybdenum demethylmenaquinol-6 L-cysteine molybdenum cofactor biosynthesis II phosphorylase: nucleotidase: reductase: a [lipoyl-carrier protein]LipB: lipB carrier-protein] purine-nucleoside 5-phosphate hydrolase: formyltetrahydrofolate -> 4)-N-acetyl- glucose/quinate/ bifunctional 2',3'- trehalose 6- 2+ 2+ AMK03_RS11275 molybdenum cofactor methoxy-6-polyprenyl- cofactor) bifunctional glutathione guanylyltransferase: lauroyl-CoA lauroyl acyltransferase: phosphopentomutase: ATP- Co DmeF Co thiamine protein activation gor 6 AMK03_RS00995 phosphorylase: AMK03_RS02190 AMK03_RS02415 CTP β-D-muramate shikimate family phosphate guanylyltransferase: aminomethylpyrimidine N -octanoyl-L-lysine reductase: fabG AMK03_RS12405 periplasmic disulfide bond formation monofunctional beta-N- cyclic-nucleotide 2'- trehalose- dependent thiamine [+ 2 isozymes] 1,4-benzoquinol molybdenum cofactor demethylmenaquinone synthase: mobA DHAP α-Kdo-(2->4)-α-Kdo-(2-> AMK03_RS00995 AMK03_RS01025 3-methyl-2-oxobutanoate 4-carboxy-4-hydroxy- DNA-3- ribonuclease HI: glycine guanylyl deoxyribose- nucleoside biosynthetic gamma- bifunctional acetylhexosaminidase: membrane-bound phosphodiesterase/ glutamate-- Clp protease diphosphokinase: a [cytidylyl molybdenum an apo acyl- mobA methylase UbiE: ubiE thiaminase guanylyltransferase: lipoyl methyltransferase/2- gshB beta-ketoacyl- glycerol-3- 6)-(lauroyl)-lipid IV (E. coli) hydroxymethyltransferase: 2-oxoadipate methyladenine AMK03_RS11815 oxidase phosphatase: A two reduced hypoxanthine xanthosine 2-deoxy-D-ribose UDP PQQ-dependent molybdenum ACP reductase: a [DsbB protein] a [DsbA protein] phosphate triphosphate peptidoglycan glutamyltransferase: ggt folylpolyglutamate beta-N- AMK03_RS19225 3'-nucleotidase: cysteine ligase: otsB ATP-binding AMK03_RS20875 cofactor chaperone]- carrier protein menaquinol-8 II: tenA mobA synthase: lipA methoxy-6-polyprenyl- bis(guanylyl phosphate an electron- 5-phosphate AMK03_RS27665 aldolase/oxaloacetate glycosylase: [+ 2 isozymes] ThiO: thiO trehalose- heme b CcmA heme b glutathione cofactor myristoyl-acyl carrier with reduced L- carrying a cysteine residues guanine aldolase: deoC dehydrogenase: AMK03_RS08890 AMK03_RS04065 thiamine cytidylyl molybdenum holo-ACP synthase: bis(guanylyl a [lipoyl-carrier 1,4-benzoquinol glutathione tungstenpterin) cofactor AMK03_RS20820 dehydrogenase: transfer quinone hydrolase: transglycosylase: gamma- synthase/ decarboxylase: AMK03_RS17430 acetylhexosaminidase: [+ 2 isozymes] subunit 4-amino-2-methyl-5- protein-dependent cysteine residues disulfide bond in a protein 3-methyl-2-oxobutanoate AMK03_RS06250 trans-methoxy- diphosphate cofactor (sulfo-dioxo) AMK03_RS07050 6 methylase UbiE: ubiE AMK03_RS02415 mtgA glutamyltransferase: ggt dihydrofolate AMK03_RS23175 AMK03_RS19225 ClpA: clpA pyrimidinemethanol molybdopterin) protein]-N -[(R)- stearate biosynthesis AMK03_RS20250 acyltransferase: xanthine purine-nucleoside deoxyribose- hydroxymethyltransferase: guanosine mono-mycolate a holo acyl- a (3R)-3-hydroxytetradecanoyl-[acp] sn-glycerol synthase: a nucleoside 5'- 3-dehydroquinate ethylamine glyoxylate cofactor dihydrolipoyl]-L-lysine menaquinol-6 guanine acetaldehyde D-glyceraldehyde 3-phosphate UMP CDP panB a DNA containing [+ 2 isozymes] N-acetyl-D- DNA γ-L-glutamyl- [+ 3 isozymes] carrier protein II (bacteria and plants) AMK03_RS12405 dehydrogenase: phosphorylase: phosphate AMK03_RS00125 an alkylated chitin monophosphate fluoride CrcB fluoride 3-phosphate di-trans,octa-cis an apurinic/ glucosamine D-alanine a peptide 3-hydroxyacyl- α-D-Kdo-(2->4)-α-D- xdhA xdhB deaminase: guaD AMK03_RS00995 aldolase: 5'/3'-nucleotidase a peptidoglycan nucleobase glycerol-3- -undecaprenyl hypoglycin B L-cysteinylglycine oxaloacetate pyruvate apyrimidinic site N-acetyl-D- ACP dehydratase a palmitoyl-[acp] Kdo-(2->6)-lipid A (E. coli) deoC SurE: surE GlcNAc phosphate 2-dehydropantoate THMPT diphosphate a (6S)-5- muramate FabZ: fabZ beta-ketoacyl- pyrimidine 5'- CMP acyltransferase: xanthine D-glyceraldehyde formyltetrahydrofolate chloride RS23045 chloride [+ 3 isozymes] ACP synthase acetaldehyde purine ribonucleosides degradation nucleotidase: AMK03_RS04835 3-phosphate acetyl-CoA II: fabF pseudouridine xanthine thymine degradation AMK03_RS02190 5'/3'-nucleotidase glutaminyl-tRNA gln Aminoacyl-tRNA Charging a (2E)-tetradec-2-enoyl-[acp] glycerol-3- degradation SurE: surE [+ 2 isozymes] dehydrogenase 32 an [L-cysteine a peptide with a [protein chain a 3-oxooctadecanoyl- uridine quinoxaline-2- a cytosine 37 4-nitrophenyl hydrogen biosynthesis via transamidation phosphate 1-O- phosphatidylcholine thymine pyrimidine 5'- cob(II)inamide an adenosine a [protein] Ser/Thr cadaverine putrescine a phenyl acetate A(H2) L-idonate L-canavanine accessory protein adenosine aryl-carrier protein desulfurase]-S- DMAPP an N-terminal (R)-β-lysine elongation factor butanoate peroxide chloride RS12505 chloride tRNA charging enoyl-ACP [acp] acyltransferase biosynthesis VI pseudouridine dihydrothymine nucleotidase: ATP carboxyl adenylate in tRNA ATP in tRNA GTP XdhC: xdhC sulfanyl-L-cysteine a tRNA precursor Xaa-L-proline P]-L-lysine 34 serine/threonine L-idonate 5- PlsY: plsY pseudouridine dehydrogenase: AMK03_RS02190 CTP glu reductase FabI: fabI 3-oxoacyl- a CDP- [+ 2 isozymes] acetyl-CoA adenosine protein kinase: dehydrogenase: diguanylate a 1-acyl-sn choline DsbA family kinase: preA homospermidine catalase/ trp a tRNA Trp his a tRNA His ile a tRNA Ile cys a tRNA Cys tRNA asp asp pro a tRNA Pro arg a tRNA Arg elongator tRNA Met met initiator tRNA Met met thr a tRNA Thr tyr a tRNA Tyr glu a tRNA glu leu a tRNA Leu phe a tRNA Phe gly a tRNA Gly enoyl-ACP [acyl-carrier- diacylglycerol deaminase: tRNA 2- tRNA (adenosine(37)-N6) AMK03_RS26115 arylesterase: arylesterase: AMK03_RS22935 cyclase: arginase: -glycerol 3- cytidine cob(I)yrinic acid a,c-diamide acyl carrier protein: leucyl 2+ 2+ reductase FabI: fabI protein] oxidoreductase: AMK03_RS11660 urate 5,6-dihydrothymine EF-P lysine synthase: peroxidase Ca RS19435 Ca val a tRNA Val ser a tRNA ser a tRNA Ala ala lys a tRNA Lys pseudouridine AMK03_RS01020 AMK03_RS12430 thiocytidine(32) CCA tRNA -dimethylallyltransferase aminopeptidase: serine/threonine AMK03_RS20410 AMK03_RS20410 L-idonate 5- AMK03_RS13065 rocF Asn Gln phosphate AMK03_RS10525 adenosyltransferase: aminoacylase AMK03_RS18510 HPI: katG asn tRNA gln a tRNA reductase: phosphatidylcholine a [DsbB protein] a [DsbA protein] dihydropyrimidinase: synthetase nucleotidyltransferase: MiaA: miaA protein kinase: dehydrogenase: a myristoyl-[acp] 1-acyl-sn-glycerol- an electron- an intra- 5'-phosphate pyrimidine deoxyribonucleotides AMK03_RS19665 [+ 3 isozymes] AMK03_RS07420 GenX: genX [+ 3 isozymes] tryptophan- histidine-- isoleucine-- cysteine-- aspartate- proline-- arginine-- methionine-- methionine-- threonine- tyrosine-- glutamate-- leucine-- phenylalanine-- glycine--tRNA ligase: fabG synthase: pcs carrying a with reduced L- hydA TtcA: ttcA AMK03_RS15730 AMK03_RS28130 c-di-GMP gln 3-phosphate transfer quinol protein disulfide xanthosine adenosine inosine guanosine AMK03_RS00175 an L-glutamyl- pseudouridine- dephosphorylation cob(I)yrinic acid a,c-diamide 2+ 2+ -tRNA tRNA ligase: tRNA ligase: tRNA ligase: -tRNA tRNA ligase: valine--tRNA ligase: tRNA ligase: serine--tRNA tRNA ligase: tRNA ligase: -tRNA tRNA ligase: alanine--tRNA tRNA ligase: lysine--tRNA tRNA ligase: tRNA ligase: pheS AMK03_RS04455 beta-ketoacyl- disulfide bond cysteine residues 6 a [protein] (L-serine/L- N-(4-aminobutyl) butanoate 4-nitrophenol acetate a phenol 5-dehydro- urea Ca RS15450 Ca Gln beta-ketoacyl-ACP acyltransferase: 3-(carbamoylamino)- N -(3-methylbut- a peptide with A H O [tRNA ] 5'-phosphate nucleoside triphosphate adenosyltransferase: cobO a quinoxaline-2- [a protein chain 2 L-canaline ligase: trpS AMK03_RS04160 AMK03_RS04210 AMK03_RS07260 ligase: aspS AMK03_RS08155 AMK03_RS09105 AMK03_RS09140 ligase: serS AMK03_RS10810 AMK03_RS10810 ligase: thrS AMK03_RS11320 ligase: alaS AMK03_RS19060 ligase: lysS AMK03_RS21335 AMK03_RS01380 AMK03_RS04500 ACP reductase: a 2-thiocytosine 32 an [L-cysteine a tRNA a proteinogenic threonine) phosphate -cadaverine D-gluconate Asp-tRNA(Asn) synthase II: fabF AMK03_RS28810 a phosphatidylcholine 2-methylpropanoate pyrophosphohydrolase: carboxyl-[aryl- 2-en-1-yl)- an N-terminal elongation factor AMK03_RS20820 glycosidase: adenosine AMP desulfurase]- 37 amino acid Asp-tRNA(Asn) purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside in tRNA containing a adenosine L-proline β /Glu-tRNA(Gln) [+ 2 isozymes] a (3R)-3- [+ 2 isozymes] AMK03_RS11665 nucleotides S-methyl-5'-thioadenosine mazG adenosylcobinamide carrier protein] L-cysteine EF-P]-N-( -L- /Glu-tRNA(Gln) an L-tryptophanyl- His Ile Cys asp Pro Val Arg ser an L-methionyl- an L-methionyl- Thr Tyr Ala Glu Lys Leu an L-phenylalanyl- Gly an L-asparaginyl- an L-glutaminyl- a 1,2-diacyl- phosphorylase: phosphorylase: phosphorylase: phosphorylase: dCTP dCMP 3' CCA end in tRNA 34 2+ 2+ amidotransferase: an L-histidyl-[tRNA ] an L-isoleucyl-[tRNA ] an L-cysteinyl-[tRNA ] an L-aspartyl-[tRNA ] an L-prolyl-[tRNA ] an L-valyl-[tRNA ] an L-arginyl-[tRNA ] an L-seryl-[tRNA ] an L-threonyl-[tRNA ] an L-tyrosyl-[tRNA ] an L-alanyl-[tRNA ] an L-glutamyl-[tRNA ] an L-lysyl-[tRNA ] an L-leucyl-[tRNA ] a glycyl-[tRNA ] 6 37 degradation IV triphosphate lysyl)-L-lysine Cd CadA Cd Trp Met Met Phe Asn Gln hydroxyoctadecanoyl- NADPH repair (prokaryotes) N -L-threonylcarbamoyladenosine degradation III gatC gatA gatB amidotransferase: [tRNA ] [elongator tRNA ] [initiator tRNA ] [tRNA ] [tRNA ] [tRNA ] a 3-oxohexadecanoyl-[acp] sn-glycerol uracil AMK03_RS00995 AMK03_RS00995 AMK03_RS00995 AMK03_RS00995 [acp] -modified tRNA biosynthesis S-methyl-5'- [+ 6 isozymes] gatC gatA gatB 3-phosphate (R)-3-amino-2- a 5-phosphooxy- 3-hydroxyacyl- AMP thioadenosine α dUTP diphosphatase: dut 3-oxoacyl-[acyl- phosphatidate NADPH methylpropanoate 5'-methylthioadenosine/ -D-ribose- β L-glutamyl- ACP AMP nucleoside triphosphate N-acetyl- -D-glucosamine- 2+ 2+ ammonium carrier-protein] cytidylyltransferase: thr 1-phosphate cob(II)alamin a proteinogenic leukotriene-C4 3-methylbutanoate glycerophosphoserine L-threo-3- quercitrin shikimate phenyl acetate L-idonate acetylene Cd CadA Cd Gln dehydratase S-adenosylhomocysteine 1,6-anhydro-N- a type IV prepilin a protein [tRNA ] acyl-CoA hydrolysis threonylcarbamoyl- nucleosidase: pyrophosphohydrolase: ATP phenylserine GTP ATP reductase: fabG AMK03_RS09685 nucleosidase: phosphopentomutase: amino acid β L-idonate 5- FabZ: fabZ AMP synthase: amn mazG acetyl- -D-muramate glucose/quinate/ ATP- nitrogenase beta-ketoacyl- phosphatidate AMK03_RS01555 AMK03_RS01025 dUTP dUMP shikimate family dehydrogenase: molybdenum- Asp-tRNA(Asn) [+ 3 isozymes] a 2,3,4-saturated AMK03_RS04545 adenine acetate- alpha-L- adenylate/guanylate adenylate/guanylate dependent zinc ACP reductase: cytidylyltransferase: (L-threonylcarbamoyl) MTR glycerophosphodiester AMK03_RS22935 Cd 2+ CadA Cd 2+ /Glu-tRNA(Gln) fatty acyl CoA D-ribose 5- cob(I)yrinic acid a,c-diamide gamma- beta-N- low specificity L- prepilin peptidase: membrane-bound cyclase domain- cyclase domain- arylesterase: metalloprotease iron protein peptidoglycan biosynthesis I (meso-diaminopimelate containing) Cell Structure Biosynthesis AMK03_RS20820 a (2E)-octadec- AMK03_RS28805 acyl-CoA (R)-NADPHX adenylate -CoA phosphodiesterase: rhamnosidase: amidotransferase: lipid IV biosynthesis (P. putida) Kdo transfer to peptidoglycan maturation (meso-diaminopimelate containing) phosphate adenosyltransferase: cobO glutamyltransferase: ggt acetylhexosaminidase: threonine aldolase: AMK03_RS26270 PQQ-dependent containing protein: containing protein: AMK03_RS20410 L-idonate 5- FtsH: ftsH subunit A 2-enoyl-[acp] thioesterase: bifunctional 5-hydroxy-CTP 5-hydroxy-CMP ligase: acs AMK03_RS09625 AMK03_RS22210 gatC gatA gatB lipid IV I (E. coli) a CDP- tRNA (adenosine(37)-N6)- AMK03_RS18575 dehydrogenase: AMK03_RS10135 AMK03_RS10135 dehydrogenase: beta: nifK α A ADP-dependent cob(I)yrinic acid a,c-diamide gamma- AMK03_RS19225 [+ 2 isozymes] a peptide UDP-N-acetyl- -D-glucosamine a (3R)-3-hydroxyhexadecanoyl-[acp] AMK03_RS13265 [+ 4 isozymes] 2+ 2+ a (3R)-3- lipid II (meso enoyl-ACP diacylglycerol threonylcarbamoyltransferase AMK03_RS06250 [+ 19 isozymes] [+ 21 isozymes] AMK03_RS28130 [+ 6 isozymes] Co Co NAD(P)H-hydrate adenosyltransferase: glutamyltransferase: ggt [+ 2 isozymes] β-L- RS29635 UDP-N-acetylglucosamine hydroxydecanoyl- UDP-N-acetyl- CMP-Kdo lipid IV (E. coli) diaminopimelate containing) reductase [+ 2 isozymes] complex ATPase subunit Fatty Acid and Lipid Degradation 3-methylbutanoyl- cyclic-GMP cyclic-AMP 5-dehydro- Mg 2+ Mg 2+ an L-glutaminyl- A a 2,3,4-saturated dehydratase/ AMK03_RS19665 quercetin 3-dehydroshikimate acetate phenol ethene α 3-hydroxyacyl- FabI: fabI diphosphate rhamnopyranose Gln 1-carboxyvinyltransferase: [acp] -D-glucosamine type 1 TsaE: tsaE AMP CoA benzaldehyde a cleaved type D-gluconate [tRNA ] monofunctional ACP dehydratase fatty acid NAD(P)H-hydrate sn-glycerol gly a peptide murA enoyl-ACP an α-(γ-L-glutamyl) 1,6-anhydro-N- ser lipid IV(A) 3- biosynthetic FabZ: fabZ epimerase: [+ 2 isozymes] oleate β-oxidation leukotriene-D4 GlcNAc 3-phosphate IV prepilin acyl-ACP--UDP-N- reductase an N 6 -L- fatty acid β-oxidation I (generic) adenosylcobalamin -L-amino acid acetyl-β-muramate UDP-N-acetyl-α-D-glucosamine-enolpyruvate deoxy-D-manno- peptidoglycan AMK03_RS10555 triphosphate Mg 2+ RS04350 Mg 2+ acetylglucosamine O- [+ 3 isozymes] 37 Aromatic Compound Degradation octulosonic acid transglycosylase: FabI: fabI (S)-NADPHX threonylcarbamoyladenine UDP-N-acetylmuramate acyltransferase: lpxA in tRNA oleate a (3Z)-alk-3- transferase: waaA mtgA a (2E)-hexadec-2-enoyl-[acp] dehydrogenase: murB a stearoyl-[acp] bifunctional enoyl-CoA aromatic compounds degradation via β-ketoadipate ala UDP-3-O-[(3R)-3- a nascent peptidoglycan long-chain fatty long-chain fatty catechol degradation III 4-sulfocatechol α a 2'- 2+ 2+ glu α α phosphatidylserine and ADP-dependent shikimate degradation I UDP-N-acetyl- -D-muramoyl- (1S,2R)-1- 4-nitrophenyl a [protein]-L- a double Mg MgtE Mg UDP-N-acetyl- -D-muramate -Kdo-(2->6)- with (L-alanyl-γ-D-glutamyl- enoyl-ACP acid activation acid--CoA ligase: ∆ 3 ∆ 2 di-trans,octa-cis- a proteinogenic glutathione a ferrocytochrome stearoyl-CoA a peptide with a shikimate [DNA] α-amylose L(or D)-O- hydroxydecanoyl]- -cis- -trans- (ortho-cleavage pathway) degradation L-alanyl-γ-D-glutamyl-L- ser C-(indol-3- deoxyribonucleoside L-allo-threonine β-isoaspartate stranded DNA a protein lipid IV (E. coli) phosphatidylethanolamine NAD(P)H-hydrate undecaprenyl phosphate amino acid b [DNA] leader sequence palmitate phosphoserine α A meso-2,6-diaminopimeloyl-D- reductase FabI: fabI AMK03_RS02460 protocatechuate 5 5'-triphosphate protein-L- 1,4-alpha-glucan N-acetyl- -D- a long-chain N-end rule pathway I (prokaryotic) enoyl-CoA lysyl-D-alanyl-D-alanine yl)glycerol glucose/quinate/ type I restriction- DNA ATP- glutamate racemase: UDP-N-acetylmuramate- alanyl-D-alanine) pentapeptide biosynthesis I dehydratase/ catechol 4-sulfocatechol shikimate phosphoserine glucosamine lipid IV biosynthesis (E. coli) KDO transferase: enoyl-ACP fatty acid isomerase: 3-phosphate shikimate family modification isoaspartate O- branching topoisomerase A NAD(P)H-hydrate oleoyl-CoA protocatechuate dependent 2+ 2+ AMK03_RS11605 -L-alanine ligase: UDP-3-O-acyl-N- waaA reductase FabI: fabI a CDP-diacylglycerol long-chain fatty leucyl/phenylalanyl- AMK03_RS07915 catechol 1,2- protocatechuate glucose/quinate/ methyltransferase: protein GlgB: glgB phosphatase Mg MgtE Mg stearate 3,4-dioxygenase: phospho-N- gamma- acyl-CoA DNA polymerase low specificity L- signal arylesterase: membrane-bound system (ATP- protease AMK03_RS14795 acetylglucosamine a (3R)-3- α α penicillin-binding CDP-diacylglycerol--serine acid--CoA ligase: epimerase: dioxygenase: 3,4-dioxygenase: shikimate family tryptophan SerB: serB cellulose -Kdo-(2->4)- -Kdo- tRNA--protein acyl-CoA acetylmuramoyl- desaturase: III subunit chi: threonine aldolase: peptidase AMK03_RS20410 PQQ-dependent endonuclease: AMK03_RS09095 1,4-alpha-glucan hydrolyzing) hydroxytetradecanoyl- protein 2: AMK03_RS02460 AMK03_RS10555 AMK03_RS13565 AMK03_RS13565 membrane-bound glutamyltransferase: ggt synthase: trpB subunit D-glt biosynthesis deacetylase: UDP-N-acetyl- (2->6)-lipid IV (E. coli) a palmitoyl-[acp] long-chain fatty O-phosphatidyltransferase: a long-chain transferase: dehydrogenase: a (2E)-2- AMK03_RS11525 pentapeptide- dehydrogenase: hsdR [+ 2 isozymes] branching subunit B: gyrB UDP-N-acetyl-α-D-muramoyl-L-alanine α A AMK03_RS14830 a [protein] enoyl-CoA catechol protocatechuate 3,4- PQQ-dependent gamma- AMK03_RS02210 AMK03_RS07425 AMK03_RS18575 I: lepB a double stranded a protein L-β- serine HslV: hslV AMK03_RS14760 [acp] -D-glucosamine a nascent peptidoglycan a mature peptidoglycan with Metabolic Regulator Biosynthesis acid--CoA ligase: pssA fatty acyl-CoA AMK03_RS09420 AMK03_RS04575 enoyl-CoA cis,cis-muconate protocatechuate AMK03_RS00115 protein GlgB: glgB γ γ a 3-sn-phosphatidyl- NADPH an N-terminal hydratase: transferase: glutamyltransferase: ggt [+ 9 isozymes] AMK03_RS06250 [+ 3 isozymes] nitrate RS08975 nitrate cellulose UDP-3-O-(3- with (L-alanyl- -D-glutamyl- (L-alanyl- -D-glutamyl-meso- N-terminal L- dioxygenase: pcaG pcaH 3,4-dioxygenase: dehydrogenase: DNA with 5'- isoaspartate a negatively a peptide a nascent peptidoglycan AMK03_RS02460 L-serine arginyl-[protein] [+ 2 isozymes] AMK03_RS01835 catechol 1,2- AMK03_RS14815 4-nitrophenol palmitate 3-dehydroshikimate amylopectin UDP-N-acetylmuramoyl- UDP- hydroxydecanoyl) acyl-ACP--UDP-N- meso-2,6-diaminopimeloyl- 2,6-diaminopimeloyl-D-alanyl- leucyl-L-arginine AMK03_RS06250 D-glyceraldehyde terminal phosphate α-methyl ester ppGpp metabolism dioxygenase: 3-carboxy-cis,cis-muconate pcaG pcaH a ferricytochrome oleoyl-CoA acetaldehyde supercoiled DNA L-alanine--D-glutamate α acetylglucosamine O- D-alanine) tetrapeptide with D,D cross-links (meso- D-alanine) pentapeptide trehalose biosynthesis V trehalose biosynthesis I trehalose stearoyl-CoA phosphatidylserine (2E,9Z)- enoyl-CoA 3-dehydroshikimate 3-phosphate trp gly a leader sequence a peptide forming - -D-glucosamine a 2,3,4-saturated AMK03_RS11525 3-sulfomuconate an α-(γ-L-glutamyl) b diaminopimelate containing) biosynthesis IV decarboxylase: octadecenoyl-CoA acyl-CoA/acyl-ACP hydratase: a 2,3,4- undecaprenyl-diphospho-N- L-cysteinylglycine 5 [DNA] ligase: AMK03_RS14810 cellulose UDP-3-O-(3- acyltransferase: lpxA palmitate leucyl/phenylalanyl- long-chain fatty 3-carboxy- UMP -L-amino acid nitrate NtrB nitrate Kdo transfer pppGpp AMK03_RS07170 fatty acid dehydrogenase: (+)-muconolactone dehydroshikimate γ synthase hydroxymyristoyl) L,D-transpeptidase: L,D-transpeptidase: a glycogen D-glucopyranose tRNA--protein enoyl-CoA AMK03_RS07915 saturated (3R)-3- cis,cis-muconate acetylmuramoyl-L-alanyl- -D- α to lipid IV UDP-α-D-glucose α acid--CoA ligase: cis,cis-muconate meso-diaminopimelate UDP-N-acetyl- -D-muramoyl- A UDP-3-O-[(3R)-3- 6-phosphate -maltose long-chain fatty AMK03_RS20945 hydroxyacyl-CoA dehydratase: glutamyl-L-lysyl- D-alanyl-D-alanine catalytic glucosamine N- AMK03_RS10110 AMK03_RS10110 glycogen debranching an L-1- transferase: hydratase: AMK03_RS02460 a 2,3,4- cycloisomerase: L-alanyl-D-glutamate IV (P. putida) hydroxymyristoyl]-N- bifunctional (p)ppGpp maltose alpha-D- a 2,3,4-saturated quinate degradation I AMK03_RS23380 lipid IV subunit: acyltransferase: [+ 10 isozymes] a nascent peptidoglycan with [+ 10 isozymes] a mature peptidoglycan a mature peptidoglycan protein GlgX: glgX acid--CoA ligase: phosphatidylethanolamine AMK03_RS09420 a [protein] AMK03_RS07915 [+ 2 isozymes] saturated (3S)-3- A synthetase/guanosine- an N-terminal AMK03_RS25720 2+ 2+ D-ala CMP-Kdo acetyl-α-D-glucosamine γ γ guanosine 3'- glucosyltransferase: AMK03_RS02460 N-terminal L- fatty acyl CoA 3-hydroxyacyl-CoA Zn RS25430 Zn (P. putida) bcsA lpxD (L-alanyl- -D-glutamyl-meso- with (L-alanyl- -D-glutamyl- with D,D cross-links (meso- glycogen debranching alpha,alpha- enoyl-CoA hydroxyacyl-CoA 4-sulfomuconolactone UDP-N-acetyl-α-D- 3-phenyl-2- a 2'- a ribonucleoside an oxidized an unstable UDP-N-acetylmuramoyl- UDP-3-O-acyl-N- 3',5'-bis(diphosphate) 3'- treS L-lysyl-[protein] (2-carboxy-2,5-dihydro- protocatechuate di-trans,octa-cis- an acyl-[acyl- adenosylcobinamide dihydroxyacetone a ribonucleoside D-glycerate [DNA] UDP-2-N-[(3R)-3- a nascent peptidoglycan 2,6-diaminopimelate) tripeptide a nascent peptidoglycan meso-2,6-diaminopimeloyl- diaminopimelate containing) diphosphate 5'- trehalose- leucyl-L-lysine hydratase: dehydrogenase: (4,5-dihydro-5- L-quinate muramoyl-L-alanyl-γ-D- tyr DL-allothreonine deoxyribonucleoside a PII protein 2',3'-cyclic repressor LexA RecA filament- L-alanyl-D-glutamate-- cellulose acetylglucosamine γ pyrophosphohydrolase: protein GlgX: glgX α,α-trehalose palmitoyl-CoA 5-oxofuran-2-yl)-acetate undecaprenyl phosphate oxopropanoate carrier protein] [DNA] 5'-monophosphate factor 420 D-alanine--D-alanine hydroxydodecanoyl]- with L,D cross links (meso- with (L-alanyl- -D-glutamyl- D-alanine) tetrapeptide triphosphate 3'- phosphate AMK03_RS22375 (+)-muconolactone oxofuran-2-yl)-acetate glucose/quinate/ 5'-triphosphate bifunctional UTP dihydroxyacetone DNA Coenzyme F420 DNA complex 2, 6-diaminopimelate lipid IV(A) deacetylase: AMK03_RS07035 a maltodextrin AMK03_RS01835 glutamyl-L-lysyl-D-alanine phosphate bifunctional 2',3'- pyrimidine 5'- glyoxylate/ DNA ligase: AMK03_RS12360 3-O-[(3R)-3- diaminopimelate containing) meso-2,6-diaminopimeloyl- diphosphatase: synthase Storage Compound Biosynthesis shikimate family kinase: transcriptional 3-deoxy- glycine betaine (S)-3-hydroxy-(9Z) coenzyme A 3-oxoadipate adenosylcobinamide nucleotidase: hydroxypyruvate polymerase hydrogenase/ repair Zn 2+ RS04915 Zn 2+ ligase: AMK03_RS14825 AMK03_RS14760 glycine) tetrapeptide AMK03_RS07035 4-carboxymuconolactone cyclic-nucleotide 2'- repressor [+ 2 isozymes] D-manno- hydroxydecanoyl]- malto-oligosyltrehalose (UDP- biosynthesis I (Gram- 2-oxoglutarate decarboxylation to succinyl-CoA Respiration enol-lactonase: membrane-bound aspartate/ kinase/ AMK03_RS13170 reductase A: III subunit dehydrogenase, protein UDP-3-O-(3- a mature peptidoglycan with -octadecenoyl-CoA decarboxylase: pcaC 2-maleylacetate phospho-N- phosphate serine DNA polymerase [protein-PII] phosphodiesterase/ AMK03_RS02190 octulosonic α-D-glucosamine synthase: treY forming): otsA polyhydroxybutanoate biosynthesis ATP pcaD PQQ-dependent tyrosine/aromatic adenosylcobinamide- dhaL dhaK AMK03_RS00930 epsilon: dnaQ beta subunit C- LexA: lexA D-alanyl-D-alanine UDP-N-acetyl-α-D-muramoyl-L-alanyl- hydroxymyristoyl) (L-alanyl-γ-D-glutamyl-meso- negative bacteria) 3-hydroxyacyl-CoA acetylmuramoyl- acyltransferase hydroxymethyltransferase: III subunit delta: uridylyltransferase: 3'-nucleotidase: 5'/3'-nucleotidase RecO: UDP-2,3- a [2-oxoglutarate biosynthesis dehydrogenase: aminotransferase: phosphate dihydroxyacetone [+ 2 isozymes] cleaved γ-D-glutamyl-meso-2,6-diaminopimelate acid -α-D-glucosamine a mature peptidoglycan 2,6-diaminopimelate) tripeptide dehydrogenase: a 2,3,4-saturated a 2,3,4-saturated pentapeptide- PlsX: plsX AMK03_RS07650 AMK03_RS21345 AMK03_RS02010 [+ 2 isozymes] a 2'- terminal domain: a stabilizedrecO GTP ppGpp a maltooligosyl-trehalose α,α-trehalose choline dehydrogenase (4,5-dihydro-5-oxofuran-2-yl)-acetate 3-oxoadipate AMK03_RS06250 AMK03_RS08890 SurE: surE predicted transferase: diacylglucosamine UDP-3-O-(3- with L,D cross-links (meso- a mature peptidoglycan fatty acyl CoA acetyl-CoA C- 3-oxoacyl-CoA transferase: AMK03_RS29595 [+ 10 isozymes] guanylyltransferase: a ribonucleoside kinase: dhaL dhaK hydroxypyruvate AMK03_RS14265 repressor LexA choline acetyl-CoA 6 ADP AMK03_RS22375 a ribonucleoside deoxyribonucleoside RecA filament- waaA diphosphatase: diaminopimelate containing) with (L-alanyl-γ-D-glutamyl- 6-phosphate E2 protein] N acyltransferase: 3-dehydroquinate cobU a reduced 2+ ABC 2+ UDP-N- hydroxymyristoyl) malto-oligosyltrehalose dehydrogenase: 2-oxoglutarate acyl CoA:acetate/ AMK03_RS14815 3'-phosphate DHAP 5'-monophosphate DNA complex Zn Zn AMK03_RS11790 -lipoyl-L-lysine flagellar 3-oxo-(9Z)- 3-oxoadipate enol- 3-(4- adenosyl-cobinamide factor 420 transporter acetylmuramoylalanyl- glucosamine N- meso-2,6-diaminopimeloyl- trehalose- acetyl-CoA C- dehydrogenase AMK03_RS22380 acyl-carrier protein an acyl phosphate acetaldehyde a uridylylated trehalohydrolase: treZ betA protein export octadecenoyl-CoA lactonase: pcaD 3-ketoacid CoA 3-oxoadipate type II 3- hydroxyphenyl) phe gly of Zn2+ D-glutamyl-2, 6- α-Kdo-(2->6) glycine) tetrapeptide phosphatase: acetyltransferase: 2-oxoglutarate E1 component: [DNA] phosphate PII protein lipid X (P. putida) acyltransferase: GDP malto-oligosyltrehalose betaine aldehyde ATPase FliI: fliI transferase: dehydroquinate undecaprenyl-diphospho-N UMP -lipid IV dehydrogenase acetyl-CoA C- pyruvate diaminopimelate--D- A lpxD bifunctional (p)ppGpp otsB AMK03_RS02840 AMK03_RS20175 γ Peptide RS15945 Peptide pyrophosphokinase: trehalohydrolase: treZ acyltransferase: 3-oxoadipate AMK03_RS08630 dehydratase: aroQ -acetylmuramoyl-L-alanyl- - alanyl-D-alanine ligase: (P. putida) UDP-2-N,3-O-bis[(3R)- synthetase/guanosine- betaine-aldehyde E1 component: [+ 2 isozymes] thiol CydD thiol lipid-A- AMK03_RS07035 α α [+ 2 isozymes] D-glutamyl-L-lysyl- D-alanine lipid IV(A) α,α-trehalose , -trehalose dehydrogenase: AMK03_RS20175 AMK03_RS22380 3-oxoacid CoA- type II 3- AMK03_RS14820 disaccharide 3-hydroxytetradecanoyl]- 3',5'-bis(diphosphate) 3'- ATP acetyl-CoA acyl CoA:acetate/ 3-deoxy- α betB acetoacetyl-CoA transferase dehydroquinate synthase: lpxB -D-glucosamine pyrophosphohydrolase: [+ 3 isozymes]a [2-oxoglutarate a [2-oxoglutarate 6 (7Z)-hexadecenoyl-CoA 3-ketoacid CoA an N -L- a 3-(acyloxy) adenosine 38- + + α D-manno- subunit A: dehydratase: aroQ 3-(N-morpholino) (R)-S- a uridine a [lipoyl-carrier (3R,5S)-3- a [protein]-α- a mismatched Na RS07695 Na UDP-N-acetyl- -D-muramoyl-L- lipid A UDP-2,3- AMK03_RS07035 dehydrogenase dehydrogenase a ferrocytochrome + acetoacetyl- transferase: a sulfurated threonylcarbamoyladenine 37 palmitoyl-CoA 2-methylbutanoate H hydrogencarbonate glycerophosphoglycerol acyl group of 2',3'-cyclic D-glycerate 6 sulfite RS02820 sulfite γ glycine betaine 6 6 AMK03_RS26440 propanesulfonate lactoylglutathione 40 in tRNA protein]-N -[(R) hydroxy-1- L-glutamate alanyl- -D-glutamyl-meso-2,6- di-trans,octa-cis-undecaprenyl phosphate octulosonic disaccharide diacylglucosamine Secondary Metabolite Biosynthesis E2 protein] N E2 protein] N -S- acyl-CoA [sulfur carrier] b DNA base pair GDP CoA reductase: AMK03_RS08630 3-dehydroshikimate in tRNA 5 bacterial toxin monophosphate RluA family glyoxylate/ -dihydrolipoyl]- pyrroline-5- protein- DNA diaminopimeloyl-D-alanyl-D-alanine acid (P. putida) diphosphatase: -dihydrolipoyl- succinyldihydrolipoyl- dehydrogenase: bifunctional 2',3'- AMK03_RS20820 3-oxoacid CoA- 3-oxoadipyl-CoA pseudouridine hydroxypyruvate L-lysine dihydrolipoyl carboxylatepyrroline-5- glutamate O- mismatch transferase: tetraacyldisaccharide AMK03_RS11790 L-lysine L-lysine AMK03_RS04575 dehydroshikimate acetate- carbonic glycerophosphodiester FMNH2-dependent cyclic-nucleotide 2'- potassium- methylerythritol phosphate pathway I methylerythritol phosphate pathway II (3R)-3- transferase subunit acyl-CoA acyloxyacyl lactoylglutathione synthase: reductase A: dehydrogenase: carboxylate methylesterase repair phospho-N-acetylmuramoyl- waaA preQ biosynthesis [+ 2 isozymes] dehydratase: tRNA (N(6)-L- -CoA alkanesulfonate phosphodiesterase/ sulfate RS19165 sulfate + + 4'-kinase: 0 hydroxybutanoyl- poly-[(R)-3- 3-oxoadipyl-CoA anhydrase: phosphodiesterase: AMK03_RS11215 AMK03_RS29940 CheR: cheR K transporting K pentapeptide- transferase: α-Kdo-(2->4)-α- lipid X A: AMK03_RS26440 AMK03_RS23380 threonylcarbamoyladenosine(37) desaturase: hydrolase: 3'-nucleotidase: lyase: gloA lpdA reductase: a [protein]-L- protein AMK03_RS04280 D-glyceraldehyde D-glyceraldehyde CoA hydroxybutanoate] (2E,7Z)- thiolase: pcaF ligase: acs AMK03_RS21265 AMK03_RS05945 monooxygenase: ATPase AMK03_RS14815 pyruvate pyruvate AMK03_RS02210 AMK03_RS11460 [+ 2 isozymes] [+ 2 isozymes] a [lipoyl-carrier AMK03_RS15560 5 MutS: mutS Kdo-(2->6)-lipid -C(2))- methylthiotransferase AMK03_RS08890 38- [+ 2 isozymes] glutamate-O a properly lipid IV lipid-A- 3-phosphate 3-phosphate hexadecenoyl-CoA 3-oxoadipyl-CoA [+ 2 isozymes] [+ 4 isozymes] ssuD a pseudouridine 6 A 2-oxoglutarate protocatechuate IV (P. putida) MtaB: mtaB hydroxypyruvate protein]-N -[(R Hyp -methyl-ester matched A (P. putida) disaccharide GTP class I poly(R)- succinyl-CoA (2S)-2- 3'-AMP 40 in tRNA predicted Co 2+ Co 2+ undecaprenyldiphospho-N-acetylmuramoyl- dehydrogenase enoyl-CoA a 3-hydroxyacyl glutathione methylglyoxal )-lipoyl]-L-lysine RS18935 synthase: lpxB 1-deoxy-D- 1-deoxy-D- GTP hydroxyalkanoic 3-oxoadipyl-CoA methylbutanoyl- diphosphate DNA base pair 2+ 2+ L-alanyl-γ-D-glutamyl-meso-2,6- E1 component: hydratase: a ferricytochrome 3-(N-morpholino) ABC Ni Ni 6 palmitoleoyl-CoA AMP sn-glycerol group of a fatty acid sulfate sulfate xylulose-5- xylulose-5- cyclohydrolase acid synthase: thiolase: pcaF a 2-methylsulfanyl-N -L- CoA CO H O glycerol sulfite diaminopimeloyl-D-alanyl-D-alanine lipid A disaccharide AMK03_RS20175 AMK03_RS07915 b 2 2 propanal transporter 7,8- 37 5'-deoxyadenosine an unsulfurated 5 3-phosphate bacterial toxin (E. coli) phosphate phosphate I FolE: folE phaC threonylcarbamoyladenine met of sulfate undecaprenyldiphospho- 2-oxoglutarate enoyl-CoA succinyl-CoA [sulfur carrier] synthase: dxs synthase: dxs dihydroneopterin in tRNA muramoylpentapeptide beta-N- tetraacyldisaccharide dehydrogenase hydratase: D-ribose RS27950 D-ribose 3'-triphosphate poly-[(R)-3- acetylglucosaminyltransferase: 4'-kinase: complex AMK03_RS01835 a sugar RS02520 a sugar 1-deoxy-D-xylulose 1-deoxy-D-xylulose 6-carboxytetrahydropterin hydroxybutanoate] murG AMK03_RS04280 dihydrolipoyllysine- a [2-oxoglutarate- di-trans,octa-cis 7,8-dihydrofolate an (R)-2- sn-glycero-3- guanosine a protein-L- (S)-3-hydroxy-(7Z) UDP-α-D-glucose + a ribonucleoside an L-aspartyl- D-glycerate pyrazinamide 5-phosphate 5-phosphate synthase QueD: queD a sulfurated dehydrogenase -undecaprenyl NADPH H methyl red a tripeptide 2',3'-cyclic L-threonine 3- a protein methionine- residue -hexadecenoyl-CoA SAM monoglutamate halocarboxylate phosphoethanolamine 3'-phosphate [tRNA Asn ] lipid II (meso diaminopimelate containing) lipid IV (E. coli) [sulfur carrier] 6 O-phosphate A 1-deoxy-D-xylulose- 1-deoxy-D-xylulose- 6-carboxy-5,6,7,8- E2 protein] N - phosphate monophosphate Asp-tRNA(Asn) glyoxylate/ bifunctional (R)-S-oxide succinyltransferase: 3-hydroxyacyl-CoA bifunctional 2',3'- bifunctional 2',3'- threonine- peptide- a sugar RS17585 a sugar 5-phosphate 5-phosphate tetrahydropterin octanoyl-L-lysine cyclic-nucleotide 2'- /Glu-tRNA(Gln) hydroxypyruvate nicotinamidase/ metalloprotease odhB dehydrogenase: Secondary Metabolite Degradation dihydrofolate HAD family glycerophosphodiester FMN-dependent cyclic-nucleotide 2'- phosphate methionine reductoisomerase: reductoisomerase: 7-carboxy-7- undecaprenyl- peptidase phosphodiesterase/ phosphodiesterase/ amidotransferase: reductase A: pyrazinamidase: TldD: tldD (R)-S-oxide AMK03_RS22375 lipoyl reductase: hydrolase: phosphodiesterase: NADH- decarboxylase: AMK03_RS19920 AMK03_RS19920 deazaguanine phosphate glucose T: pepT 3'-nucleotidase: 3'-nucleotidase: gatC gatA gatB AMK03_RS00930 pncA reductase 3-oxo-(7Z)- superpathway of hexuronide myo-inositol degradation I synthase: AMK03_RS02800 AMK03_RS19180 AMK03_RS09625 azoreductase: (R)-1-amino-AMK03_RS12455 a sugar RS03650 a sugar synthase phosphotransferase: AMK03_RS08890 AMK03_RS08890 an L-asparaginyl- [+ 2 isozymes] [+ 2 isozymes] a peptide MsrB: msrB superpathway of L-tryptophan biosynthesis Amino Acid Biosynthesis MEP MEP hexadecenoyl-CoA and hexuronate degradation 4-deoxy-L-threo-hex-4- D-galactarate N-acetylglucosamine L-idonate degradation lipA [+ 2 isozymes] [+ 5 isozymes] [+ 4 isozymes] AMK03_RS08880 Asn 2-propanol O pyrazine-2- L-histidine biosynthesis superpathway of L- L-arginine QueE: queE 2-oxoisovalerate decarboxylation to isobutanoyl-CoA AMK03_RS07850 [tRNA ] hydroxypyruvate a [protein]-L- superpathway of L- superpathway of branched chain amino acid biosynthesis L-lysine biosynthesis I L-arginine biosynthesis II (acetyl cycle) superpathway of L- acetyl-CoA C- enopyranuronate degradation degradation I degradation II a ribonucleoside 3'-GMP -2-phosphate carboxylate isoleucine biosynthesis I phenylalanine biosynthesis degradation I 7-carboxy-7- myo-inositol a proteinogenic a dipeptide methionine D-erythrose threonine biosynthesis bifunctional 2-C- bifunctional 2-C- acyltransferase: a β-D-glucuronoside a [2-oxoglutarate phosphoenolpyruvate (arginase pathway) an [apo BCAA dehydrogenase 4-deoxy-L-threo-hex- N-acetyl-D- L-idonate 5'-deoxyadenosine an unsulfurated 5,6,7,8- an (S)-2- N,N-dimethyl-1,4- amino acid 4-phosphate PRPP D-erythrose phosphoenol N-acetylglutamyl- deazaguanine galactarate met dehydrogenase α-D-glucopyranosyl- UMP NADP + a halide anion ethanolamine sn-glycerol anthranilate a sugar RS22200 a sugar pyruvate methyl-D-erythritol methyl-D-erythritol E2 protein] N 6 -lipoyl-L-lysine AMK03_RS22380 inositol 2- 4-enopyranuronate glucosamine L-idonate 5- phenylenediamine oxaloacetate thr asp phosphate oxaloacetate galactarate N-acetylglucosamine 6 [sulfur carrier] diphosphoundecaprenol tetrahydrofolate hydroxycarboxylate 3-phosphate 4-phosphate pyruvate 4-phosphate 4-phosphate 7-cyano-7- dehydrogenase: dehydrogenase: E2 protein] N aspartate/ ATP aspartate/ arg kinase: 3-deoxy-7- acetolactate aspartate kinase: cytidylyltransferase/ cytidylyltransferase/ deazaguanine (5Z)-tetradecenoyl-CoA dehydratase: -lipoyl-L-lysine tyrosine/aromatic threonine/serine iolG AMK03_RS28130 phosphoribosyltransferase synthase AMK03_RS19500 N-acetyl- tyrosine/aromatic arginase: 2-C-methyl-D- synthase AMK03_RS29345 N-acetyl-D-AMK03_RS15065 a sugar RS22755 a sugar phosphoheptulonate 3-deoxy-7- dehydratase: 2-C-methyl-D- acyl-CoA/acyl-ACP D-glucopyranuronate 5-dehydro-4- L-idonate 5- aminotransferase: regulatory subunit: catalytic subunit: gamma- aminotransferase: rocF QueC: queC scyllo-inosose 5-dehydro-4-deoxy- synthase: phosphoheptulonate erythritol 2,4- erythritol 2,4- deoxy-D-glucarate glucosamine an L-1- 10 34 a thiocarboxylated 2251 AMK03_RS29595 AMK03_RS04165 AMK03_RS18430 L-aspartyl-4-phosphate glutamyl- AMK03_RS29595 dehydrogenase: D-glucuronate dehydrogenase: an L-lysyl- an L-methionyl- an N - a uridine an (S)-2- O-succinyl-L- a [release factor]- guanosine 1,6-anhydro-N- a supercoiled a nucleoside AMK03_RS11845 synthase: AMK03_RS30930 L-ornithine cyclodiphosphate cyclodiphosphate 6-phosphate phosphatidyl- isethionate L,L- an unfolded 7-cyano-7- Lys Met [SAMP] C- β a protein [+ 2 isozymes] phosphate 3-methyl-2- AMK03_RS20945 myo-inosose-2 AMK03_RS22935 [tRNA ] [initiator tRNA ] formyltetrahydrofolate in tRNA halocarboxylate homoserine diaminopimelate L-glutamine in 23S rRNA acetyl- -muramate duplex DNA hypoxanthine triphosphate aspartate ATP AMK03_RS11845 acetolactate aspartate synthase: synthase: 5-dehydro- N-acetylglucosamine- 5-dehydro- sn-glycerol terminal glycine peptide chain 23S rRNA anhydro-N- UvrD-helicase protein 3-deoxy-7- aspartate- reductase: ornithine--oxo-acid deazaguanine oxopentanoate [+ 2 isozymes] dehydratase: iolE LL-diaminopimelate nucleoside a sugar RS19010 a sugar transaminase: phosphoribosyltransferase: (2Z)-2-aminobut- synthase: ilvN transaminase: AMK03_RS09820 AMK03_RS09820 4-deoxy-D- 6-phosphate D-gluconate release factor (guanosine(2251) acetylmuramic domain-containing chaperonin phosphoheptulonate 3-deoxy-7- semialdehyde acetylglutamate synthase: dehydrogenase: myo-inosose-2 aminotransferase: xanthine triphosphate endopeptidase AMK03_RS09935 AMK03_RS04170 2-enoate AMK03_RS14495 argC AMK03_RS09935 transaminase: 3-methyl-2- (2E,5Z)- aldehydo-D- glucuronate tartronate deacetylase: nagA HAD family FMNH2-dependent GroEL: groL synthase class II: phosphoheptulonate dehydrogenase: kinase: argB 4-(cytidine 5'- 4-(cytidine 5'- AMK03_RS23545 AMK03_RS22395 aldehydo-D-glucuronate 5-keto-D-gluconate bifunctional methionyl-tRNA tRNA 2- O-succinylhomoserine N(5)-glutamine -2'-O)- acid kinase: protein: dehydrogenase: hydrolase: La: lon AMK03_RS19985 oxobutanoate tetradecenoyl-CoA galacturonate dehydratase: iolE isomerase: semialdehyde hydrolase: alkanesulfonate AMK03_RS24195 [+ 2 isozymes] AMK03_RS11875 asp 1-(5-phospho- synthase class II: AMK03_RS21250 gln N-acetyl-L-glutamate asp diphospho)-2-C- diphospho)-2-C- an [apo BCAA dehydrogenase D-glucosamine 5-reductase: lysylphosphatidylglycerol formyltransferase: thiouridine(34) sulfhydrylase: methyltransferase: methyltransferase AMK03_RS11315 AMK03_RS14655 xdhA xdhB AMK03_RS02415 (S)-2-acetolactate glu N-acetyl-L-glutamate preQ [+ 3 isozymes]dehydrogenase (2- glucuronate glucuronate 3D-(3,5/4)- kduI AMK03_RS19180 monooxygenase: LL-diaminopimelate N-acetyl-D- β-D-ribosyl)-ATP 5-semialdehyde L-glutamate-5- methyl-D-erythritol methyl-D-erythritol 0 6 2-hydroxy-3- 6-phosphate AMK03_RS22945 synthase prmC RlmB: rlmB [+ 4 isozymes] 6,8- a nucleoside a sugar RS23090 a sugar AMK03_RS11875 an [apo BCAA dehydrogenase E2 E2 protein] N -S-[2- ∆ 3 2 flippase/synthetase AMK03_RS02155 AMK03_RS02650 L-aspartate 4- bifunctional methylpropanoyl- -cis-∆ -trans- enoyl-CoA isomerase: isomerase: trihydroxycyclohexane- ssuD aminotransferase: 5 2-O- muramate 6- a protein a peptide 3-deoxy-D-arabino- semialdehyde 4-(cytidine 5'- 4-(cytidine 5'- 6 3-deoxy-D-glycero- oxopropionate MnmA: mnmA [+ 5 isozymes] a [release factor]-N a single dihydroxypurine diphosphate aspartate kinase: phosphoribosyl-ATP ketol-acid glutamine- N-acetylornithine aspartate kinase: protein] N -dihydrolipoyl-L-lysine methylpropanoyl]dihydrolipoyl- MprF: mprF 2251 phosphate 2-iminobutanoate semialdehyde glutamate N- transferring): enoyl-CoA hydratase: uxaC uxaC 1,2-dione D-gluconate AMK03_RS09465 -methyl-L-glutamine methylguanosine stranded DNA heptulosonate AMK03_RS19500 diphosphatase: 3-deoxy- aminotransferase: AMK03_RS19500 diphospho)- diphospho)- L-lysine 2,5-hexodiulosonate reductase: (S)-2,3,4,5- reductoisomerase: acetyltransferase/ hydrolyzing bifunctional trifunctional AMK03_RS22390 isomerase: AMK03_RS01835 3D-(3,5/4)- an N-formyl- in 23S rRNA 7-phosphate AMK03_RS00210 D-arabino- 2-C-methyl-D- 2-C-methyl-D- AMK03_RS30765 a tetrahydrofolate 34 succinate ilvC 4-hydroxy- amino-acid carbamoyl- AMK03_RS02630 transcriptional D-tagaturonate D-fructuronate trihydroxycyclohexane- 2-dehydro- α gluconokinase: L-methionyl- a [SAMP] C- a 2-thiouridine an (S)-2- L-homocysteine glycolaldehyde sulfite tetrahydrodipicolinate a sugar RS19335 a sugar 3-dehydroquinate glutamate N- erythritol kinase: erythritol kinase: AMK03_RS22395 AMK03_RS02845 enoyl-CoA -D-glucosamine 3-O-L-lysyl-1-O- a halide anion L-aspartyl- β heptulosonate (2R)-2,3- tetrahydrodipicolinate L-aspartyl- 3-deoxy-D- Lys met terminal glycine in tRNA hydroxycarboxylate 1-(5-phospho- - acetyltransferase phosphate acetyltransferase/ regulator/proline 1,2-dione acylhydrolase D-glycerate 6-phosphate AMK03_RS22950 phosphatidylglycerol a tRNA [initiator tRNA ] synthase: 4-phosphate 7-phosphate dihydroxy-3- synthase: 4-phosphate AMK03_RS04415 AMK03_RS04415 3-methyl-2- hydratase: D-ribosyl)-AMP L-arginine biosynthesis I (via L-ornithine) ArgJ: argJ synthase: amino-acid dehydrogenase/L- NADH repair (prokaryotes) (decyclizing): iolD gluconate 5- gluconokinase: AMK03_RS19845 3-dehydroquinate 2-phospho-4-(cytidine 2-phospho-4-(cytidine myo-inositol oxobutanoate (3E,5Z)-tetradeca- AMK03_RS07915 phosphoribosyl- 2-oxobutanoate methylbutanoate AMK03_RS07015 carA carB glutamate gamma- dehydrogenase AMK03_RS03840 aspartate- (2S,4S)-4- acetyltransferase aspartate- 5'-diphospho)-2-C- 5'-diphospho)-2-C- biosynthesis 3,5-dienoyl-CoA glycerate kinase: a sugar RS23270 a sugar synthase: dihydroxy-acid semialdehyde dehydrogenase:2-oxo acid 5-deoxy-D-glucuronate KduD: kduD 3-dehydroquinate semialdehyde AMP ArgJ: argJ semialdehyde D-altronate D-mannonate AMK03_RS09005 D-gluconate 2503 34 uridine 2'3'-cyclic an [amino-group carrier 4-methyl-3- AMK03_RS19845 hydroxy-2,3,4,5- L-ornithine methyl-D-erythritol methyl-D-erythritol NADH AMK03_RS20140dehydrogenase acyl-CoA (S)-3-hydroxy-(5Z) adenine a [protein]-S- a uridine an N-acetyl-β- a cytidine 34 β-D-glucose cyclohydrolase: acetolactate dehydratase: glu carbamoyl phosphate dehydrogenase: D-glucopyranose 2-dehydro-3- glycyl-glycine glutathione isobutanoate an α L-rhamnoside aci-nitroethane an L-glutamyl- long chain dehydrogenase: tetrahydrodipicolinate dehydrogenase: bifunctional 2-C- bifunctional 2-C- thioesterase: -tetradecenoyl-CoA 2-phospho- F6P 6-phosphate D-hexosaminide monophosphate protein]-C-terminal-γ- oxoadipate- ilvD N-acetyl-L-ornithine subunit E2: 5-deoxy- in 23S rRNA sulfanyl-L-cysteine in tRNA in tRNA [tRNA Gln ] purine 6-phosphate polyphosphate type II 3- AMK03_RS21250 hisI synthase putA 6-phosphate deoxy-D-gluconate bifunctional 2',3'- (L-glutamyl)-L-glutamate enol-lactone 3-dehydroquinate 4-hydroxy- bifunctional AMK03_RS21250 methyl-D-erythritol methyl-D-erythritol inositol-3- AMK03_RS22400 AMK03_RS13265 3-hydroxyacyl-CoA glucuronate D-glycerate tRNA (cytidine(34) Asp-tRNA(Asn) inositol-3- polyphosphate dehydroquinate 1-(5-phospho-β-D-ribosyl)- catalytic subunit: 3-methyl-2- mannonate cyclic-nucleotide 2'- 3-oxoadipate a sugar RS07835 a sugar L-aspartate 4- tetrahydrodipicolinate 4-phosphate 4-phosphate phosphate [+ 2 isozymes] dehydrogenase: altronate acetylglutamate -2'-O)- phosphate kinase 2: ppk2 dehydratase: aroQ type II 3- AMK03_RS30930 oxobutanoate glutamate N- L-aspartate 4- glu 3-methyl-2- dehydratase: isomerase: 23S rRNA tRNA 2- alpha-L- beta-N- nitronate /Glu-tRNA(Gln) xanthine enol- 5-[(5-phosphoribosylamino) reductase: synthase: dehydratase: gamma- acetate--CoA phosphodiesterase/ methyltransferase: synthase: semialdehyde acetyltransferase/ semialdehyde cytidylyltransferase/ cytidylyltransferase/ oxobutanoate (3E,5Z)- AMK03_RS22375 AMK03_RS10315 AMK03_RS22270 D-galactonate degradation rhamnosidase: acetylhexosaminidase: monooxygenase: kinase: argB amidotransferase: dehydrogenase: polyphosphate lactonase: type II 3- methylideneamino]imidazole- dehydroquinate acetolactate AMK03_RS02540 (adenine(2503)-C(2) glutamyltransferase: ggt thiouridine(34) 3'-nucleotidase: AMK03_RS14250 AMK03_RS00885 amino-acid 2-C-methyl-D- 2-C-methyl-D- AMK03_RS14250 (R)-NADHX tetradecadienoate ligase: acs AMK03_RS22210 AMK03_RS19225 an [amino-group carrier a 2'-O- AMK03_RS15700 gatC gatA gatB xdhA xdhB kinase 2: ppk2 pcaD dehydroquinate homoserine 4-carboxamide dehydratase: aroQ synthase: ilvN 2-isopropylmalate branched-chain homoserine dehydrogenase: 3-oxo-(5Z)- mannonate 5-deoxy- )-methyltransferase gamma- synthase AMK03_RS02575 AMK03_RS08890 ornithine erythritol 2,4- Ins(3)P KDGP 34 an L-glutaminyl- long chain 4-methyl-3- a sugar RS27940 a sugar dehydrogenase: synthase: leuA 4-hydroxy- acetyltransferase erythritol 2,4- bifunctional AMK03_RS20140 tetradecenoyl-CoA dehydratase: glucuronate D-galactarate [+ 2 isozymes] protein]-C-terminal- methylcytidine 8-hydroxypurine Ins(3)P dehydratase: aroQ 1-(5-phosphoribosyl)-5- type II 3- AMK03_RS14495 amino acid dehydrogenase: D-galactonate RlmN: rlmN glutamyltransferase: ggt MnmA: mnmA Gln polyphosphate ArgJ: argJ carbamoyltransferase: cyclodiphosphate cyclodiphosphate ADP-dependent degradation II D-sorbitol degradation I 3'-UMP γ-(5-phospho-L- [tRNA ] oxoadipate AMK03_RS09470 [(5- phosphoribosylamino) tetrahydrodipicolinate AMK03_RS09470 acetyl-CoA C- uxuA isomerase: iolB β-L- a non in tRNA dehydroquinate (S)-2-aceto-2- aminotransferase: AMK03_RS10145 synthase: synthase: inositol 3-dehydroshikimate (2S)-2- reductase: NAD(P)H-hydrate acyltransferase: 5-dehydro-2- galactonate isobutanoyl-CoA diphosphate rhamnopyranose rhamnosylated β acetaldehyde nitrite glutamyl)-L-glutamate methylideneamino]imidazole-4- dehydratase: aroQ hydroxybutanoate AMK03_RS06100 N-acetyl-L- 2-dehydro-3-deoxy- 2503 AMP 34 an N-acetyl- - L-homoserine AMK03_RS31580 ornithine L-homoserine AMK03_RS09820 AMK03_RS09820 monophosphatase: dehydratase/ galactarate dehydratase: D-sorbitol a 2-methyladenine γ-L-glutamyl- a [protein]- a 2-thiouridine an alcohol a sugar RS26900 a sugar carboxamide isomerase: hisA isopropylmalate glutamate AMK03_RS22380 deoxy-D-gluconate phosphogluconate 5'-deoxyadenosine met L-cysteinylglycine rhamnosyl D-hexosamine shikimate ketol-acid branched-chain carbamoyltransferase: AMK03_RS10645 NAD(P)H-hydrate galactarate dgoD L-iditol 2- in 23S rRNA glycylglycine L-cysteine in tRNA 3-dehydroshikimate 3-isopropylmalate (S)-2,3,4,5- 2-C-methyl-D-erythritol- 2-C-methyl-D-erythritol- (3Z)-dodec- 5-dehydro-2- aldolase: acceptor dehydrogenase: phosphoribulosylformimino- reductoisomerase: amino acid argF [+ 4 isozymes] epimerase: TCA cycle TCA cycle I (prokaryotic) dehydratase: dehydrogenase: homoserine kinase: dehydratase tetrahydrodipicolinate acetylglutamate homoserine kinase: 2,4-cyclodiphosphate 2,4-cyclodiphosphate 3-enoyl-CoA deoxygluconokinase: AMK03_RS18955 2-dehydro-3-deoxy- AMK03_RS11490 AICAR-phosphate shikimate ilvC aminotransferase: AMK03_RS29345 AMK03_RS23395 AMK03_RS04860 kinase: argB AMK03_RS04860 AMK03_RS10555 2-dehydro-3- iolC 5-dehydro-4- D-galactonate dehydrogenase: large subunit: leuC AMK03_RS14200 2,3,4,5- flavodoxin- flavodoxin- myo-inositol (S)-NADHX ∆3,∆2-enoyl- a sugar RS08650 a sugar [+ 3 isozymes] (R)-2,3-dihydroxy- deoxy-D-gluconate keto-D-fructose an N-terminal (S)-5-amino-3- an [RNA]-3'- a uracil 1498 a [protein]- 6-O-cis-methoxy- 3-isopropylmalate tetrahydropyridine- acetyl-CoA CoA isomerase: 5-dehydro-2-deoxy-D- D-glyceraldehyde deoxy-D-glucarate 2-dehydro-3- an N-terminal an L-phenylalanyl- an apo [peptidyl- an L-arginyl- acetyl-CoA 2-oxoglutarate (S)-2- a holo [PedN acyl- roseoflavin an aromatic O-phospho- imidazole AMK03_RS11490 3-methylpentanoate N-acetylglutamyl- O-phospho- dependent dependent pyruvate coenzyme A 3-sulfino-L- D-ala glu dihydrolipoamide ribonucleoside- mycolyl-trehalose gly 2,6-dicarboxylate N- bifunctional 3-phosphate 5-dehydro-4- deoxygalactonokinase: arginyl-[protein] [tRNA Phe ] [tRNA Arg ] oxohexanoate aminobutanoate carrier protein] in 16S rRNA L-tyrosine amino acid shikimate L-homoserine dehydratase phosphate (E)-4-hydroxy- (E)-4-hydroxy- AMK03_RS02845 gluconate 6-phosphate carrier protein] alanyl-[protein] 2',3'- 16S rRNA polysaccharide bifunctional 6-phosphate glycerol [+ 3 isozymes] dihydroxy-acid L-homoserine ADP-dependent pyruvate aspartate/ small subunit: leuD val succinyltransferase: L-citrulline biosynthesis oxaloacetate ∆ 3 2 deoxyglucarate AMK03_RS04320 ACP S- trehalose- glycine phosphate dehydratase: 3-methylbut- 3-methylbut- -cis-∆ -trans- dehydrogenase cyclophosphate (uracil(1498)-N(3))- biosynthesis riboflavin kinase/ a sugar RS27280 a sugar shikimate kinase: threonine synthase: dapD N-acetyl- NAD(P)H-hydrate citrate synthase: dehydratase: 2-dehydro-3-deoxy- 3-keto-5- RNA 2',3'-cyclic tyrosine/aromatic phosphatase: shikimate L-citrulline threonine synthase: 2-enyl- 2-enyl- enoyl-CoA leucyl/phenylalanyl- complex malonyltransferase: methyltransferase: tyrosine autokinase: FAD synthetase: oxidase AMK03_RS19850 synthase: ilvD 2-isopropylmaleate gamma- dehydratase/ AMK03_RS10940 D-galactonate β-D-fructofuranose holo-ACP synthase: D-amino-acid glutamate-- phosphodiesterase: aminotransferase: AMK03_RS04945 N-succinyl-2-amino- AMK03_RS04945 diphosphate diphosphate isomerase: KDGP kdgD arginyltransferase: aminohexanoate fabD AMK03_RS04205 otsB ThiO: thiO hisF hisH tRNA--protein transaminase: cysteine ligase: dihydrolipoamide 3 AMK03_RS04070 AMK03_RS16855 trehalose- shikimate kinase: (3S)-3-methyl-2- glutamyl- gln indole-3-acetate NAD(P)H-hydrate [+ 2 isozymes] 6-phosphate AMK03_RS07050 AMK03_RS07620 cleavage protein: a malonyl[PedN thpR an N - a [protein]- AMK03_RS29595 3-isopropylmalate 6-ketopimelate argininosuccinate synthase: ispG synthase: ispG AMK03_RS07915 2,5- fructokinase: transferase: acetyltransferase: an [RNA]-3'- roseoflavin an aromatic glyoxylate shikimate 3-phosphate AMK03_RS19850 oxopentanoate phosphate biosynthesis epimerase: malate DHAP 3-oxopropanoate AMK03_RS09975 AMK03_RS04065 acyl-carrier methyluracil 1498 L-tyrosine cis-methoxy- a sugar RS28440 a sugar thr D-erythro-1- synthase: thr (E)-4-hydroxy-3- (E)-4-hydroxy-3- dioxopentanoate AMK03_RS02445 AMK03_RS09420 AMK03_RS22850 ribunucleoside- 5'-phosphate 2-oxo-acid dehydratase reductase: Asp-tRNA(Asn) IV (bacteria) AMK03_RS10555 dehydrogenase: (2E)-dodec- 2-dehydro-3-deoxy- 2-dehydro-3-deoxy-6- AMK03_RS09770 protein] in 16S rRNA phosphate mono-mycolate AICAR (imidazol-4- branched-chain methylbut-2-en- methylbut-2-en- 2'-phosphate shikimate 3- large subunit: leuC argC AMK03_RS20345 mdh 2-enoyl-CoA phosphogluconate malonate phosphogalactonate a holo [peptidyl- an N-terminal L- S-acetyldihydrolipoamide 3-phosphoshikimate 1- threonine/serine amino acid /Glu-tRNA(Gln) L-methionine biosynthesis III (indol-3-yl) 3',5'-ADP γ-L-glutamyl-(S)- yl)-glycerol 1-yl diphosphate 1-yl diphosphate NADH (S)-malate citrate semialdehyde F6P carrier protein] a tRNA Arg arginiyl-3-sulfino- (S)-3- pyruvate carboxyvinyltransferase: phosphate aminotransferase: 3-isopropylmalate N-succinyl-L,L-2,6- N-acetyl-L- amidotransferase: acetonitrile enoyl-CoA aldolase: aldolase: L-phenylalanyl-L- acetoacetate D-glt dehydratase: 3-phosphate L-arginino-succinate 4-hydroxy- 4-hydroxy- nitrile a tRNA Phe 2-aminobutanoate AMK03_RS04470 3-phosphoshikimate 1- dehydratase glutamate 5- gatC gatA gatB hydratase: AMK03_RS18955 dehydrogenase: AMK03_RS04315 arginyl-[protein] L-alanyl-[protein] aminobutanoyl-CoA a sugar RS12335 a sugar AMK03_RS18430 imidazoleglycerol- AMK03_RS06100 diaminopimelate pro 3-methylbut- 3-methylbut- hydratase: 2-oxoglutarate carboxyvinyltransferase: small subunit: leuD semialdehyde argininosuccinate [+ 6 isozymes] L-homoserine aconitate AMK03_RS07915 AMK03_RS03805 5-enolpyruvoyl- [+ 2 isozymes] phosphate branched-chain succinyl- N-acetylornithine 2-enyl 2-enyl nthB nthA fumarate hydratase: AMK03_RS04470 (2R,3S)-3- lyase: argH (indol-3-yl) hydratase enoyl-CoA D-glyceraldehyde D-glyceraldehyde shikimate 3-phosphate (2Z)-2-aminobut- dehydratase amino acid diaminopimelate aminotransferase: hydrogencarbonate trifunctional homoserine O- diphosphate diphosphate AMK03_RS11930 pyruvate acetyl-CoA pyruvate 5-enolpyruvoyl- isopropylmalate glu acetamide AcnA: acnA hydratase: 3-phosphate 3-phosphate an apo-[LYS2 L- an N-terminal an (S)-2- a guanine 527 a [protein]- 6-O-trans-keto- a sugar RS10265 HisB: hisB aminotransferase: desuccinylase: transcriptional reductase: reductase: an N-terminal an L-phenylalanyl- an L-arginyl- an L-arginyl- N,N'-diacetylchitobiose a holo [PedD acyl- propionamide a sugar chorismate 2-enoate shikimate 3- AMK03_RS02630 acetyltransferase: 4-hydroxy- 4-hydroxy- class II fumarate coenzyme A 2-aminoadipyl- 3-sulfo-L- a protein canavaninosuccinate acetoacetyl-CoA thr mycolyl-trehalose D-ala 3-(imidazol-4- 3-isopropylmalate dapE arg amidase: AMK03_RS01835 L-lysyl-[protein] [tRNA Phe ] [tRNA Arg ] [tRNA Arg ] halocarboxylate carrier protein] in 16S rRNA L-histidine synthase: AMK03_RS14200 glutamine- regulator/proline AMK03_RS20890 3-methylbut- ispH 3-methylbut- ispH hydratase: fumC carrier-protein] alanyl-[protein] 16S rRNA 3-hydroxybutyryl- amidase: 6-phosphate yl)-2-oxopropyl phosphate N-acetyl-L- glutamate 5-kinase: AMK03_RS27090 fumarate cis-aconitate threonine/serine sensor histidine aroC dehydrogenase: hydrolyzing dehydrogenase/L- 2-enyl 2-enyl (S)-3- ACP S- trehalose- glycine chorismate ornithine O-acetyl-L- IPP IPP aconitate chitooligosaccharide (guanine(527)-N(7) CoA AMK03_RS27090 kinase KdpD: phosphate ile leuB L,L-diaminopimelate carbamoyl- glutamate gamma- AMK03_RS21085 amidase: hydroxydodecanoyl-CoA HAD family malonyltransferase: dehydratase: phosphatase: oxidase a sugar RS10370 a sugar gln synthase: homoserine hydrogen sulfide diphosphate diphosphate hydratase leucyl/phenylalanyl- deacetylase argininosuccinate )-methyltransferase dehydrogenase: amidase: AMK03_RS26765 chorismate histidinol- (2S)-2-isopropyl- acetylornithine phosphate semialdehyde AMK03_RS01115 Inorganic Nutrient Metabolism holo-ACP synthase: arginyltransferase: arginyltransferase: hydrolase: AMK03_RS18430 otsB 2-iminobutanoate aroC γ-L-glutamyl reductase: reductase: AcnA: acnA SDR family NAD(P) tRNA--protein lyase: argH fabD RsmG: rsmG AMK03_RS19685 AMK03_RS01115 a [protein]- ThiO: thiO phosphate diaminopimelate AMK03_RS07050 NodB: nodB a malonyl- an N 7 - (S)-3- trehalose- 3-oxosuccinate deacetylase: synthase: dehydrogenase: 5-phosphate ispH ispH -dependent AMK03_RS07620 AMK03_RS07620 AMK03_RS19180 [+ 2 isozymes] epimerase: dapF type 2 isopentenyl- type 2 isopentenyl- (indol-3-yl)acetate transferase: 527 propanoate N-phospho- trans-keto- pyruvate transaminase: chorismate argE carA carB putA O-acetylhomoserine oxidoreductase: (aminomethyl)phosphonate degradation [+ 6 isozymes] [PedD acyl- methylguanine hydroxybutanoyl- 2-oxobutanoate anthranilate diphosphate diphosphate glyphosate degradation III methylphosphonate dimethyl sulfide assimilatory two-component alkanesulfonate monooxygenase assimilatory AMK03_RS09420 β L-histidine mono-mycolate a sugar RS22960 a sugar hisC diaminopimelate aminocarboxypropyltransferase: AMK03_RS22375 a holo-[LYS2 L- N-acetyl- -D- carrier protein] in 16S rRNA CoA synthase: carbamoyl (S)-1-pyrroline- glutamate-5- Delta-isomerase: Delta-isomerase: degradation I degradation sulfate reduction IV sulfate reduction III an N-terminal L- acetate L-canavanine fumarate [+ 2 isozymes] chorismate mutase: L-proline biosynthesis epimerase: L-ornithine AMK03_RS07935 succinate D-threo-isocitrate 3',5'-ADP 2-aminoadipyl- an N-terminal glucosaminyl-(1->4) AMK03_RS15845 5-carboxylate AMK03_RS24900 AMK03_RS24900 (aminomethyl)phosphonate Arg arginiyl-3-sulfo- Arg 4-methyl-2- AMK03_RS20495 phosphate semialdehyde NADP-dependent 3-oxododecanoyl-CoA glyphosate II (oxidation) L-phenylalanyl- a tRNA a tRNA arginyl-[protein] a (2R)-2- -D-glucosamine 2-oxobutanoate AMK03_RS20510 I (from L-glutamate) an alkylsulfonate FMNH Phe carrier-protein] a halide anion L-histidinol dehydrogenase: isocitrate methylphosphonate sulfate 2 sulfate L-lysyl-[protein] a tRNA L-alanyl-[protein] hydroxy fatty acid oxopentanoate ADP-forming phosphonate dimethyl sulfide a sugar RS13145 a sugar phosphate ornithine AMK03_RS21090 dehydrogenase: acetyl-CoA C- phosphonate sulfate sulfate anthranilate acetolactate prephenate branched-chain meso-diaminopimelate L-homocysteine DMAPP DMAPP succinate--CoA C-P lyase histidinol- glu carbamoyltransferase: AMK03_RS11625 acyltransferase: (acetamidomethyl)phosphonate C-P lyase adenylyltransferase: adenylyltransferase: synthase amino acid ligase: sucD sucC system protein anthranilate phosphatase: prephenate glutamate 5-kinase: AMK03_RS10145 AMK03_RS22380 system protein cysN cysD cysN cysD RNase III mRNA an α(1,5)- 966 a 5,6- catalytic subunit: aminotransferase: diaminopimelate L-glutamate-5- methionine methionine PhnL: phnL 5-methoxy-6- lysine within an (R)-2- + a guanine dimethyl sulfoxide NaMN an apo-[aryl- a holo [BryU acyl- 20 3'-cmp D-ribofuranose sn-glycerol hisN dehydratase: AMK03_RS21085 phosphonate C- PhnL: phnL APS APS coenzyme A an octanoyl-[acp] processing FMN NADH H L-arabinan dihydrouracil ser citrate a sugar RS28995 a sugar phosphoribosyltransferase: trpD AMK03_RS30930 γ AMK03_RS06100 decarboxylase: lysA ornithine semialdehyde synthase: synthase: decanoyl-CoA α-D-ribose-1-[[+N 2- isozymes] methylbenzimidazole gcv protein H halocarboxylate in 16S rRNA 3-phosphate AMK03_RS00695 -L-glutamyl arg succinyl-CoA 2-oxoglutarate P lyase system carrier protein] carrier protein] in tRNA bifunctional 2',3'- ribokinase: carbamoyltransferase: metH metH α-D-ribose-1-[+ 2 isozymes] substrate 16S rRNA tRNA glycerol-3- aconitate N-(5-phosphoribosyl) acetolactate histidinol 5-phosphate branched-chain protein PhnL: phnL (phosphonomethyl) phosphoadenylyl- ACP S- cyclic-nucleotide 2'- AMK03_RS22735 threonine/serine 3-phenyl-2- argF superpathway of L-serine acyl-CoA methylphosphonate- alpha-N- (guanine(966)-N(2) hydratase -anthranilate synthase: ilvN amino acid lys ornithine--oxo-acid glycine] 5-triphosphate sulfate reductase: nicotinate-nucleotide-- HAD family flavin reductase: malonyltransferase: dihydrouridine(20/ phosphate dehydratase: oxopropanoate glutamate-5- and glycine biosynthesis I [+ 2 isozymes] FMNH2-dependent lipoyl(octanoyl) )-methyltransferase phosphodiesterase/ ribokinase: AMK03_RS14495 histidinol met dehydrogenase: α alpha-D-ribose 1- 5-triphosphate flavin reductase: AMK03_RS05775 holo-ACP synthase: hydrolase: AMK03_RS22085 arabinofuranosidase: 20a) synthase dehydrogenase: AMK03_RS18430 AcnA: acnA predicted phosphoribosylanthranilate semialdehyde aminotransferase: arginase: transaminase: -D-ribose 1- alkanesulfonate dimethylbenzimidazole transferase ribonuclease III: fabD RsmD: rsmD 3'-nucleotidase: AMK03_RS02125 dehydrogenase: aspartate AMK03_RS04575 methylphosphonate alpha-D-ribose 1- dimethyl sulfone PAPS AMK03_RS22085 phosphoribosyltransferase: AMK03_RS07050 AMK03_RS07060 AMK03_RS19180 AMK03_RS26405 a malonyl- an N 2 - DusA: dusA glpD [+ 2 isozymes] ABC isomerase: AMK03_RS00105 (S)-2-aceto-2- dehydrogenase: AMK03_RS14200 rocF AMK03_RS19985 3-phospho-D-glycerate 2-oxoglutarate (acetamidomethylphosphonate) monooxygenase: LipB: lipB [+ 2 isozymes] AMK03_RS08890 D-ribofuranose D-threo-isocitrate a sugar a sugar hisD transaminase: asp L-citrulline glycolysis III (from glucose) Glycolysis methylphosphonate [+ 2 isozymes] sulfite methylguanine 966 20 DHAP transporter hydroxybutanoate [+ 2 isozymes] 5-triphosphate 5-triphosphate ssuD cobT [BryU acyl- a uracil in tRNA 5-phosphate pyruvate 1-(2- AMK03_RS21090 phosphoglycerate dehydrogenase 5-triphosphate dimethylsulfone phosphoadenylyl- [+ 5 isozymes] cytidine AMK03_RS09935 leu uracil degradation alpha-D-ribose 1- diphosphatase: a [glycine-cleavage an α(1,5)- α-L- carrier protein] in 16S rRNA of a sugar carboxyphenylamino) ketol-acid histidinal dehydrogenase: E1 component: (2E)-dec-2-enoyl-CoA monooxygenase: a holo-[aryl- RNase III I (reductive) diphosphatase: sulfate reductase: 3',5'-ADP + L-arabinan arabinofuranose reductoisomerase: aspartate/ L-glutamate-5- L-ornithine ammonia assimilation cycle III D-glucopyranose AMK03_RS20175 methylphosphonate AMK03_RS00810 5-methoxy-6- acyl-carrier protein complex H protein] an mRNA fragment FMNH NAD -1-deoxy-D-ribulose argininosuccinate AMK03_RS05185 AMK03_RS00810 ssuD AMK03_RS05775 carrier protein] processing a (2R)-2- 2 histidinol tyrosine/aromatic semialdehyde L-cysteine biosynthesis I uracil enoyl-CoA 5-triphosphate methylbenzimidazole nicotinate N 6 -octanoyl-L-lysine a halide anion predicted 5-phosphate ilvC synthase: alpha-D-ribose 1- product mRNA hydroxy fatty acid aminotransferase: ornithine phosphoglycerate glucokinase: hydratase: diphosphatase: alpha-D-ribose 1- methanesulfinate ABC indole-3- (R)-2,3-dihydroxy- dehydrogenase: AMK03_RS20345 dihydropyrimidine ammonium methylphosphonate sulfite hydrogen sulfide ribotide phosphate a sugar a sugar AMK03_RS29595 carbamoyltransferase: dehydrogenase: AMK03_RS00895 AMK03_RS07915 AMK03_RS00810 methylphosphonate transporter glycerol 3-methylpentanoate hisD dehydrogenase: preA 5-triphosphate ser AMK03_RS10145 AMK03_RS18005 glu D-glucopyranose Pentose Phosphate Pathways 5-triphosphate of a sugar phosphate L-arginino- 5,6-dihydrouracil enoyl-CoA alpha-D-ribose 1- diphosphatase: dihydroxy-acid 3-phosphooxypyruvate glutamine a 2-oxo adenine 2030 46 his phe (S)-1-pyrroline- ornithine 2-oxoglutarate glutamate 6-phosphate hydratase: AMK03_RS07535 diphosphatase: 5-methoxybenzimidazole NaMN coenzyme A AsbD acyl- hydrogen selenide a peptide with a rutin a holo [BryP acyl- a guanine (S)-5-hydroxyisourate 3'-UMP glutathione acetamide histidinol 7,8-dihydropterin synthase dehydratase: serine O- succinate synthetase: methylphosphonate an aldehyde FMN carboxylate L-ornithine O-acetyl-L-serine 5-carboxylate carbamoyltransferase: synthase glucose-6- pentose phosphate pathway α-D-ribose-1-[N- AMK03_RS07535 carrier protein penultimate glycine in 23S rRNA carrier protein] in tRNA predicted TrpC: trpC acetyltransferase: cysE dihydropyrimidinase: phosphoserine AMK03_RS15000 AMK03_RS01835 5-triphosphate α 23S rRNA tRNA bifunctional 2',3'- protein- amidase: ilvD pyrroline-5- argininosuccinate argF large phosphate (phosphonomethyl) -D-ribose-1- methanesulfonate hydrogen sulfide histidinol guanine ABC hydA transaminase: (S)-3- diphosphatase: (adenine(2030)-N(6) ACP S- (guanosine(46)-N7) hydroxyisourate cyclic-nucleotide 2'- glutamate O- AMK03_RS27090 a sugar a sugar (1S,2R)-1-C-(indol-3- (3S)-3-methyl-2- carboxylate serine O- lyase: argH [+ 4 isozymes] isomerase: pgi D-glucopyranose methylphosphonate alpha-L- dehydrogenase: deaminase: transporter AMK03_RS18010 subunit: gltB AMK03_RS07535 glycine] 5-phosphate nicotinate-nucleotide-- ornithine--oxo-acid cysteine malonyltransferase: hydrolase: uraH yl)glycerol 3-phosphate oxopentanoate acetyltransferase: cysE L-citrulline 6-phosphate hydroxydecanoyl-CoA 5-phosphate FMNH2-dependent )-methyltransferase -methyltransferase phosphodiesterase/ methylesterase amidase: hisD guaD reductase: 3-ureidopropanoate Asp-tRNA(Asn) α-D-ribose-1-(2-N- alpha-D-ribose 1- dimethylbenzimidazole holo-ACP synthase: carboxypeptidase: rhamnosidase: fabD of a sugar alpha-D-ribose 1- alkanesulfonate transaminase: synthase RlmJ: 7 TrmB: trmB (S)-2-oxo-4- 3'-nucleotidase: CheR: cheR AMK03_RS01115 branched-chain AMK03_RS15560 arg /Glu-tRNA(Gln) F6P (S)-3- methylphosphonate phosphoribosyltransferase: AMK03_RS07050 AMK03_RS22210 a malonyl- an N - 7,8- tryptophan L-alanine alanine glycine O-acetyl-L-serine O-phospho-L-serine glucose-6- acetamidomethylphosphonate) monooxygenase: thiosulfate oxidation III (multienzyme complex) AMK03_RS19985 A: cysK AMK03_RS01745 AMK03_RS07520 hydroxy-4-carboxy- AMK03_RS08890 his hydrogen sulfide ammonium gln hydroxydecanoyl- methylphosphonate 6 [BryP acyl- methylguanine 46 S-methylglutathione acetate dihydrolumazine synthase: trpB amino acid biosynthesis III racemization biosynthesis IV amidotransferase: phosphate 5-phosphate 5-phosphate C- cobT an N - a sugar RS29280 a sugar 6-phosphofructokinase: CoA 5-phosphate C- ssuD 2030 5-ureidoimidazoline uridine AMK03_RS00115 aminotransferase: pro gatC gatA gatB dehydrogenase: alpha-D-ribose 1- P-lyase PhnJ: β-L- methyladenine carrier protein] in tRNA phosphoserine AMK03_RS14880 dehydrogenase: P-lyase PhnJ: a [SoxY protein]-L-cysteine a holo-[AsbD acyl- a proteinogenic L-glutamate-5- quercetin- AMK03_RS06100 [+ 6 isozymes] zwf methylphosphonate 5- AMK03_RS00855 sulfite 3',5'-ADP acetate a peptide with a rhamnopyranose in 23S rRNA ser cys ala thr cysteine synthase phosphatase SerB: serB AMK03_RS00855 carrier protein] L-selenocysteine 3-glucoside indole β β-D-fructose 1,6- AMK03_RS22375 5-methoxybenzimidazole nicotinate amino acid semialdehyde an amino acid branched-chain cysteine alanine racemase: low specificity L- L-glutamate A: AMK03_RS08935 -alanine glucose-6- phosphate C-P-lyase 5-phospho-α-D-ribose C-terminal glycine predicted bisphosphate carbon-phosphorus ribotide phosphate amino acid desulfurase: AMK03_RS23110 threonine aldolase: biosynthesis III cysteine synthase A: cysK ser phosphate 3-oxodecanoyl-CoA PhnJ: AMK03_RS00855 1,2-cyclic phosphate ABC lyase complex a sugar a sugar tryptophan aminotransferase: AMK03_RS11275 [+ 2 isozymes] AMK03_RS18575 glu dehydrogenase: carbon-phosphorus transporter subunit PhnI: a [SoxY protein]-S- synthase: trpB AMK03_RS14200 D-ala gly 2-oxoglutarate serine fructose- AMK03_RS06065 acetyl-CoA C- lyase complex subunit α (9Z,15Z)-12,13- [+ 2 isozymes] urea cycle 3-aci- N,N',N''- a [DNA]-3'- p-nitrophenyl- -L- α-D-glucopyranose guanine 37 of a sugar glutamate cys acyltransferase: AMK03_RS00860 selenate reduction sulfosulfanyl-L-cysteine 5-hydroxybenzimidazole NaMN coenzyme A [EntB aryl- D-glucopyranose D-glycerate 5-hydroxy- a DNA segment an aliphatic nitrile AMK03_RS00115 hydroxymethyltransferase: bisphosphate 6-phospho PhnI: AMK03_RS00860 rhamnopyranoside epoxy-octadeca- Phe Ins(1)P ala synthase large 5-phospho-α- nitropropanoate triacetylchitotriose hydroxyl CTP 1-phosphate in tRNA L-tryptophan ile AMK03_RS07650 aldolase class I: D-glucono- AMK03_RS22380 α-D-ribose 1,5- carrier protein] 9,15-dienoate tRNA glucose 1- 2-hydroxy-3- subunit: gltB 5-phospho-α-D-ribose D-ribose 1,2- cytochrome c: inositol recombinase nitrile predicted AMK03_RS18250 1,5-lactone bisphosphate arg (guanosine(37)-N1) dehydrogenase: oxopropionate aromatic amino octanoyl-CoA 1,2-cyclic phosphate cyclic phosphate selenate AMK03_RS17630 beta-N- alpha-L- epoxide hydrolase: monophosphatase: RecA: recA hydratase: ABC trp glu gly nicotinate-nucleotide-- nitronate exodeoxyribonuclease glucose-1-phosphate AMK03_RS26210 acid lyase: a sugar a sugar 6-phosphogluconolactonase: sulfate holo-ACP synthase: rhamnosidase: AMK03_RS26710 -methyltransferase AMK03_RS10645 reductase: [+ 2 isozymes] nthB nthA transporter ribose 1,5- [+ 5 isozymes] dimethylbenzimidazole monooxygenase: acetylhexosaminidase: III: AMK03_RS20570 cytidylyltransferase: AMK03_RS01815 triose-phosphate pgl acyl-CoA adenylyltransferase: AMK03_RS22210 (9Z,15Z)-12,13- 1 TrmD: trmD [+ 3 isozymes] AMK03_RS30765 a DNA segment a primary of a sugar bisphosphate phosphoribosyltransferase: AMK03_RS07050 AMK03_RS02575 nagZ [+ 2 isozymes] rfbF an N - [+ 4 isozymes] tartronate dehydrogenase: a [SoxY protein]-S- a [SoxY protein]-S 37 D-glucono- serotonin in reverse isomerase: D-gluconate phosphokinase: adenosine 5'-cysN cysD dihydroxyoctadeca- methylguanine myo-inositol aliphatic amide Nucleoside and Nucleotide Biosynthesis α disulfanyl-L-cysteine -sulfanyl-L-cysteine cobT [+ 2 isozymes] 1,5-lactone semialdehyde AMK03_RS27965 AMK03_RS04575 -D-ribose 1,5- 9,15-dienoate Phe orientation a sugar RS13840 a sugar 6-phosphate α phnN phosphoselenate [unspecified β-L- α in tRNA [+ 2 isozymes] -D-ribose 1,5-bisphosphate bisphosphate a holo-[EntB aryl- a [DNA]-3'- a 2'- 4-nitrophenol CDP- -D-glucose triose-phosphate decarboxylating 6- 3',5'-ADP 3-oxopropanoate nitrite N-acetyl-D- rhamnopyranose superpathway of pyrimidine PRPP arginase: carrier protein] degradation N,N'- deoxyribonucleoside isomerase: ammonium 5-hydroxybenzimidazole nicotinate hydroxyl Carbohydrate Biosynthesis superpathway of superpathway of superpathway of pyrimidine deoxyribonucleoside salvage adenine and adenosine salvage III guanine and guanosine salvage phosphogluconate (2E)-oct-2-enoyl-CoA ribose 1,5-bisphosphate rocF products] diacetylchitobiose glucosamine 5'-monophosphate deoxyribonucleotides de novo biosynthesis pyrimidine nucleobases salvage II AMK03_RS10960 argininosuccinate ribotide phosphate adenosine nucleotides guanosine nucleotides D-glyceraldehyde dehydrogenase: gnd phosphokinase: phnN adenine predicted DHAP glutamine- L-cysteine degradation III de novo biosynthesis I de novo biosynthesis I 2'-deoxycytidine 3-phosphate D-ribulose enoyl-CoA phosphoribosyltransferase: selenite lyase: argH ABC gluconeogenesis I gln cytosine hydratase: hydrolyzing a [SoxY protein]-S-(2- a sugar a sugar α PRPP biosynthesis glycogen biosynthesis I (from ADP-D-Glucose) GDP-L-fucose hydrogencarbonate guanosine type I 5-phosphate PRPP AMK03_RS25350 L-arginino- transporter UDP- -D-glucose UDP-N-acetyl-D- adenine cytosine deaminase: L-ornithine UDP-N-acetyl- decaprenyl-diphospho-N- (9Z,12Z)-15,16- 37 purine-nucleoside AMK03_RS07915 succinate carbamoyl- sulfodisulfanyl)-L-cysteine [EntF L-seryl- a sialyloligosaccharide a single- (2E,6E)-farnesyl (R)-S- dCDP a guanine D-glucopyranose of a sugar biosynthesis glucosamine biosynthesis I biosynthesis I (from IMP asp IMP nucleoside purine-nucleoside AMK03_RS10210 glyceraldehyde- adenine cys α-D-glucosamine acetylmuramoyl-pentapeptide coenzyme A protoheme epoxyoctadeca- Ins(2)P a uridine in tRNA thr DNA with lesion pyruvate D-ribose 5- adenine phosphate stranded RNA diphosphate lactoylglutathione vitamin B12-dependent in tRNA (S)-malate GDP-D-mannose) Aromatic Compound Biosynthesis deaminase: phosphorylase: phosphorylase: uracil 3-phosphate ribulose-phosphate ribose-5- enoyl-CoA phosphoribosyltransferase: carrier protein] 9,12-dienoate glucose 1- excinuclease D-glucopyranose phosphate D-glucopyranose D-glucopyranose 6-phosphate glutamine-hydrolyzing phosphoribosyltransferase: synthase: tRNA inositol tRNA pyruvate ribose-phosphate IMP AMK03_RS09995 AMK03_RS00995 dehydrogenase: 3-epimerase: phosphate hydratase: AMK03_RS15660 argininosuccinate ribonucleotide reductase: dehydrogenase: L-threonine 3- ABC subunit predicted GDP-α-D-mannose carbamoyl-phosphate dCMP AMK03_RS00995 uracil AMK03_RS25350 carA carB undecaprenyldiphospho- epoxide hydrolase: (guanosine(37)-N1) monophosphatase: dihydrouridine carboxylase: 6-phosphate 6-phosphateglucose-6- dehydrogenase: guanine gap AMK03_RS11380 AMK03_RS01835 selenodiglutathione synthase: exo-alpha-sialidase: AMK03_RS08825 dehydrogenase: ABC alpha-D-glucose pyrophosphokinase: alpha-D-glucose GDP-mannose phenylethanol biosynthesis synthase: carA carB adenylosuccinate [+ 2 isozymes] adenosine isomerase muramoylpentapeptide beta-N- polyribonucleotide protoheme IX hydroxyacylglutathione AMK03_RS26710 -methyltransferase AMK03_RS12930 synthase UvrA: uvrA a sugar a sugar 3-(4-hydroxyphenyl) (d)CMP kinase: phosphoribosyltransferase: upp adenine AMK03_RS20345 holo-ACP synthase: AMK03_RS28480 AMK03_RS10645 pyc phosphate-specific AMK03_RS15600 phosphate phosphate-specific 4,6-dehydratase: synthase: guaB RpiA: rpiA (S)-3- diphosphate carbamoyl nucleotidyltransferase: pnp farnesyltransferase: hydrolase: gloB class 1b ribonucleoside- TrmD: trmD [+ 3 isozymes] DusB: dusB tdh transporter pyruvate biosynthesis AMK03_RS00505 acetylglucosaminyltransferase: AMK03_RS07050 (9Z,12Z)-15,16- an N 1 - [+ 4 isozymes] [+ 2 isozymes] malate phosphoglucomutase: isomerase: pgi phosphoglucomutase: AMK03_RS17375 2'-deoxyuridine adenosine xanthine UMP 13-DPG D-xylulose phosphoribosyltransferase: ornithine phosphate 2-oxo-3- exo-alpha-sialidase: diphosphate a 5,6-dihydrouridine DNA without oxaloacetate of a sugar ribose-phosphate gmd hydroxyoctanoyl-CoA murG AMK03_RS04820 37 D-glucono- aminoacetone dehydrogenase: phe phosphoribosyltransferase: gpt AMK03_RS15660 RdgB/HAM1 family carbamoyltransferase: sulfanylpropanoate AMK03_RS05450 dihydroxyoctadeca- methylguanine myo-inositol α AMK03_RS18730 pyrophosphokinase: F6P AMK03_RS18730 carbamoyl phosphate asp XMP dCDP deaminase: 5-phosphate D-ribose 5- reductase: nrdF nrdE 1,5-lactone in tRNA lesion mdh -D-glucopyranose GDP-mannose SDR family NAD(P) nitrogen fixation a holo-[EntF 9,12-dienoate in tRNA α-D-glucopyranose tyr thymidine kinase: AMK03_RS01020 hypoxanthine phosphoglycerate phosphate non-canonical AMK03_RS10145 a nucleoside a single- CDP predicted 1-phosphate AMK03_RS25375 glutamine-- 4,6-dehydratase: adenylo-succinate -dependent diphosphate I (ferredoxin) glutathioselenol decaprenyl-pyrophosphoryl- 3',5'-ADP (R)-lactate glutathione aspartate AMK03_RS15890 phosphoribosyltransferase: hpt kinase: purine NTP ornithine 3-mercaptopyruvate UDP L-seryl-carrier stranded RNA ABC malate PRPP 1-phosphate gmd glutamine- transketolase: oxidoreductase: N-acetylneuraminate an oligosaccharide diphosphate ferroheme o a sugar UTP--glucose- fructose-6- aromatic amino transaminase: aspartate AMK03_RS18245 pyrophosphatase: carbamoyltransferase: sulfurtransferase: (N-acetylglucosamine)-N- protein] a sugar transporter dehydrogenase: GDP-4-dehydro- adenylosuccinate hydrolyzing GMP thymidine inosine AMK03_RS22375 N polyphosphate metabolism phosphate glucose-1-phosphate acid lyase: dCTP AMK03_RS12005 RdgB/HAM1 family non- 2 L-citrulline sseA acetylmuramyl-(pentapeptide) AMK03_RS02025 1-phosphate α-D-rhamnose AMK03_RS09935 carbamoyltransferase synthase: guaA dUMP GMP rdgB argF of a sugar oxaloacetate transaminase adenylyltransferase: AMK03_RS01815 lyase: 3-phospho-D-glycerate transketolase: tkt canonical purine NTP nitrogenase uridylyltransferase GDP-L-fucose aspartate/ catalytic subunit: purine-nucleoside 3-oxooctanoyl-CoA [+ 3 isozymes] (isomerizing) glgC phenylacetaldehyde AMK03_RS11395 thymidine kinase: pyrophosphatase: rdgB molybdenum- long chain GalU: galU synthase: AMK03_RS08255 thymidylate D-sedoheptulose D-glyceraldehyde hydrogen selenide a [glycine-cleavage (12Z,15Z)-9,10- a negatively dimethyl(3- predicted pyruvate tyrosine/aromatic GMP AMK03_RS15890 phosphorylase: 2,3-bisphosphoglycerate- [+ 3 isozymes] iron protein polyphosphate hydrogen sulfide pyruvate an N-terminal L- an L-arginyl- RNase R degradation naringin UDP a [protein]- : glmS α α AMK03_RS03990 Amine and Polyamine Biosynthesis 7-phosphate 3-phosphate acetyl-CoA C- phosphate complex H protein] coenzyme A coenzyme A epoxyoctadeca- 3-aminopropanal oxaloacetate oxopropyl) 3-cyanopyridine phosphoenolpyruvate UDP-α-D-glucose a (1->4)- -D-glucan ADP- -D-glucose 2-phenylethylamine alcohol aminotransferase: synthase: AMK03_RS00995 dependent subunit a sulfurated [sulfur carrier] SAM aspartyl-[protein] Arg VibB substrate RNA L-homoserine supercoiled DNA L-glutamine ABC AMP acyltransferase: 6 [tRNA ] vitamin B12-dependent a sugar a sugar carboxykinase: D-glucosamine GDP-4-dehydro-6- dehydrogenase 3-(4- AMK03_RS29595 AMK03_RS14550 N -octanoyl-L-lysine 12,15-dienoate DNA betaine-aldehyde citrate synthase/ sulfanium chemoreceptor nitrile transporter glycogen N-carbamoyl-L-aspartate phosphoglycerate AMK03_RS22380 phosphate beta: nifK dimethylsulfoniopropanoate ribonucleotide reductase: betaine-aldehyde AMK03_RS00190 6-phosphate deoxy-β-L-galactose hydroxyphenyl) guanylate ectoine biosynthesis transaldolase: tal epoxide hydrolase: homoserine O- topoisomerase dehydrogenase: methylcitrate glutamine of a sugar AdhP: adhP hypoxanthine mutase: degradation I (cleavage) polyphosphate alpha-L- AMK03_RS08825 hydratase: synthase pyruvate kinase: gmk guanine and guanosine salvage II putrescine homospermidine [+ 6 isozymes] ribonuclease CoA pyrophosphatase: succinyltransferase: IV subunit B: parE synthase: dehydrogenase: deamidase phosphoglucosamine GDP-L-fucose adenylate kinase: AMK03_RS00880 hexanoyl-CoA glyphosate ammonium kinase 2: ppk2 exopolyphosphatase: ppx arginyltransferase: holo-ACP synthase: rhamnosidase: AMK03_RS26710 betB nthB nthA GlgA: glgA dihydroorotase: pyrC biosynthesis I biosynthesis I lipoyl R: rnr class 1b ribonucleoside- AMK03_RS20890 AMK03_RS10945 betB CheD: cheD mutase: synthase: 2-phenylethanol AMK03_RS19810 5-aminoimidazole ribonucleotide biosynthesis I xanthine D-erythrose DMSP [+ 2 isozymes] AMK03_RS07620 AMK03_RS07050 AMK03_RS15735 AMK03_RS22210 (12Z,15Z)-9,10- [+ 2 isozymes] predicted phosphoenolpyruvate α dihydroorotase: dTMP asp 2,3-bisphosphoglycerate- F6P degradation II synthase: lipA diphosphate β (2S,3S)-2- a [protein]-α- nicotinamide AMK03_RS18020 a (1->4)- -D-glucan AMK03_RS03990 adenylate kinase: phosphoribosyltransferase: gpt 4-phosphate acyl-CoA dihydroxyoctadeca- O-succinyl-L- a relaxed DNA -alanine DMSP ABC GDP putrescine a sugar a sugar α AMK03_RS08250 guanosine aspartate kinase: arg dependent dehydrogenase: reductase: nrdF nrdE homoserine methylcitrate L-glutamate phosphopyruvate -D-glucosamine AMK03_RS08520 dTMP kinase: hypoxanthine transketolase: glyphosate an N-terminal β-L- 12,15-dienoate transporter 1,4-alpha-glucan GDP-β-L-fucose PRPP homospermidine phosphoglycerate dimethylsulfoniopropionate AMK03_RS19500 AMK03_RS04575 long chain a [glycine-cleavage Arg a holo-[VibB aryl- a nucleoside 5'- prunin dUDP of a sugar hydratase: eno 1-phosphate branching (S)-dihydroorotate AMK03_RS10825 phosphoribosyltransferase: hpt synthase: AMK03_RS12005 glycine a tRNA L-arginiyl-L- 3',5'-ADP a diribonucleotide 3',5'-ADP 4'-phosphopantetheine rhamnopyranose ADP mutase: lyase: AMK03_RS30180 5'-deoxyadenosine 6 an unsulfurated monophosphate bifunctional UDP-N- L-aspartyl- [+ 2 isozymes] oxidase polyphosphate met complex H protein] N aspartyl-[protein] carrier protein] protein GlgB: glgB class 1b dTDP amidophosphoribosyltransferase: AMK03_RS18510 AMK03_RS24215 transketolase: tkt [sulfur carrier] 2-phospho-D-glycerate acetylglucosamine 4-phosphate agmatine sym- ThiO: thiO -[(R)-lipoyl]-L-lysine predicted 1,4-alpha-glucan quinone-dependent vitamin B12- ribonucleoside- AMK03_RS07275 IMP D-glyceraldehyde (2E)-hexenoyl-CoA (aminomethyl) α guanine homospermidine ABC glycogen biosynthesis III (from -maltose 1-phosphate) diphosphorylase/ dihydroorotate dependent diphosphate β aspartate- 2-phospho-D-glycerate 3-phosphate acrylate dimethyl sulfide branching 5-phospho- - gly agmatinase: phosphonate a sugar transporter a sugar glucosamine-1- dehydrogenase: enoyl-CoA 1518 a 3,5,7,9,11,13,15- protein GlgB: glgB ribonucleotide GTP reductase: D-ribosylamine semialdehyde speB a [pyruvate dehydrogenase E2 an N-terminal L- poly-3- adenine / a [protein]-L- γ-glutamyl- phosphate N- dTDP-N-acetylthomosamine AMK03_RS02740 dTTP xanthine an L-arginyl- dioscin a ribonucleoside a single vernolate trans-aconitate 2-chloroacetate CAIR ethanol of a sugar reductase: nrdF nrdE dehydrogenase: phosphopyruvate hydratase: a sulfurated [sulfur carrier] SAM 6 1519 hepta-oxo- ω trp D-glucopyranose 6-phosphate ADP-α-D-glucose phosphoribosyltransferase: gpt agmatinase: protein] N -octanoyl-L-lysine glutamyl-[protein] [tRNA Arg ] hydroxyoctanoate triphosphate adenine in 16S rRNA proline ( = 180) isopropylamide acetyltransferase a glycogen biosynthesis PRPP hydratase: eno AMK03_RS07915 stranded DNA 16S rRNA hexadecanoyl-[PKS-acp] peptidylprolyl haloacid 5-(carboxyamino) orotate AMK03_RS08825 vitamin B12- phosphoribosylamine- AMK03_RS21250 speB aldo/keto trans-aconitate 2- catalase/ 3-phospho-D-glycerate GlmU: glmU hypoxanthine epoxide hydrolase: ferredoxin: aromatic amino predicted α-D-glucopyranose -glycine ligase: purD enoyl-CoA (adenine(1518)-N(6)/ reductase: methyltransferase: isomerase: dehalogenase imidazole peroxidase class 1b dependent adenine and phosphoribosyltransferase: hpt L-aspartate 4- polyhydroxyalkanoate alpha-L- ABC N-acetyl-α-D- putrescine phosphoenolpyruvate hydratase: adenine(1519)-N(6))- AMK03_RS26710 AMK03_RS10605 type II: AMK03_RS24730 acid lyase: ribonucleotide a sugar a sugar phosphoglycerate 1-phosphate orotate ribonucleoside- ribonucleotide semialdehyde Amino Acid Degradation arginyltransferase: depolymerase: rhamnosidase: DNA primase: AMK03_RS09905 tam HPI: katG adenosine salvage I dimethyltransferase (9Z)-12,13- (E)-3- AMK03_RS29970 AMK03_RS01815 mutase: purE transporter kinase: glucosamine glucose-1-phosphate phosphoribosyltransferase: reductase: AMK03_RS01835 lipoyl synthase: lipA AMK03_RS07620 AMK03_RS15300 [+ 19 isozymes] [+ 5 isozymes] γ diphosphate GAR GMP pyruvate AMK03_RS00090 AMK03_RS22210 9-hydroxy-3,5,7,11,13,15- a [protein]-L- N-( -L-glutamyl) acetaldehyde of a sugar AMK03_RS18245 1-phosphate thymidylyltransferase 6 RsmA: rsmA1518 dihydroxyoctadeca- (methoxycarbonyl) glycolate tryptamine AIR AMK03_RS02440 reductase: AMK03_RS08825 (S)-3- L-valine degradation I N -dimethyladenine hexaoxohexadecanoyl- ω -L-alaninol CMP-3-deoxy-D- RfbA: rfbA kinase: pyk L-isoleucine degradation I L-leucine degradation I L-histidine degradation II L-threonine L-tyrosine degradation I 9-enoate pent-2-enedioate proline ( = 0) bifunctional UDP-N- dTDP-α-D-glucose nrdF nrdE phosphoribosylglycinamide adenosine hydroxyhexanoyl-CoA L-glutamate an N-terminal /N 6 -dimethyladenine 1519 [PKS-acp] 13-DPG manno-octulosonate degradation I poly-3- poly-3- 3-O-β-D-glucosyl- predicted acetylglucosamine formyltransferase: purine-nucleoside glycolysis IV degradation VI a [pyruvate dehydrogenase a tRNA Arg L-arginiyl-L- L-rhamnopyranose ssDNA/pppN(pN) in 16S rRNA alpha-D-glucose L-2,4- pyruvate 3-hydroxyhexanoyl- 5'-deoxyadenosine ABC diphosphorylase/ biosynthesis dTDP-glucose 4,6- orotidine 5'-phosphate AMK03_RS07540 val (to pyruvate) met 6 an unsulfurated [sulfur carrier] hydroxyoctanoate hydroxyoctanoate diosgenin hybrid a sugar a sugar phosphorylase: homospermidine CoA his E2 protein] N -lipoyl-L-lysine glutamyl-[protein] n -1 triose-phosphate type I phosphate-specific D-ribulose dehydratase: rfbB dADP dGDP diaminobutanoate ile leu tyr transporter α,α-trehalose 6-phosphate glucosamine-1- AMK03_RS00995 biosynthesis II dehydrogenase: thr isomerase: glyceraldehyde- phosphoglucomutase: 5-phosphate dTDP-4-dehydro-6- orotidine-5'-phosphate FGAR F6P branched-chain histidine aspartate glu of a sugar phosphate N- inosine-5'-phosphate biosynthesis I adenine AMK03_RS02845 branched-chain threonine/serine AMK03_RS27965 3-phosphate AMK03_RS18730 α branched-chain amino acid ammonia-lyase: transaminase: trehalose- acetyltransferase deoxy- -D-glucopyranose decarboxylase: pyrF putrescine amino acid dehydratase: cytidine 2',3'-cyclic 6-O-cis-keto- phosphoribosylformylglycinamidine pyrophosphate-- 3-hydroxyacyl-CoA amino acid AMK03_RS25865 AMK03_RS09935 UDP-N-acetyl-α-D-glucosamine undecaprenyl-diphospho-N a 2-deoxy-D- S-(2-hydroxyacyl) an insertion sequence adenosyl-cob(III) (2S)- predicted triose-phosphate dehydrogenase: phosphatase: otsB GlmU: glmU aldehydo-D- dTDP-4-amino-4,6- adenine 6-phosphofructokinase: aminotransferase: aminotransferase: a nucleobase a peptidoglycan fumarate a glycogen a folate MeOH UMP AIR homospermidine fructose-6-phosphate AMK03_RS18430 -acetylmuramoyl-L-alanyl-γ- asp monophosphate element IS30 yrinate a,c-diamide ethylphosphate mycolyl-trehalose L-dopa isomerase: gap arabinose 5- dideoxygalactose synthase: purS purQ purL (2S)-4-acetamido- dehydrogenase: aminotransferase: AMK03_RS06100 histidine aspartate/ ribosyl-base glutathione ethylmalonyl-CoA ABC UDP-N-acetyl- GDP-mannose biosynthesis phosphoribosyltransferase: synthase: AMK03_RS14880 AMK03_RS06100 [+ 2 isozymes] D-glutamyl-L-lysyl- D-alanine bifunctional 2',3'- dihydrofolate 6-phosphate a sugar a sugar α,α-trehalose phosphate UMP kinase: 2-aminobutanoate 1-phosphotransferase: AMK03_RS22375 AMK03_RS06100 ammonia- (2Z)-2-aminobut- tyrosine/aromatic transposase: cobyric acid alkaline methylmalonyl- catalase/ transporter AMK03_RS10960 D-glyceraldehyde α-D-glucosamine transaminase: rffA 5-(carboxyamino)imidazole AMK03_RS25350 AMK03_RS18510 branched-chain cyclic-nucleotide 2'- trehalose- aromatic amino DHAP dGTP FGAM sym- AMK03_RS14880 branched-chain 2-enoate undecaprenyldiphospho- AMK03_RS12625 reductase: synthase: CoA peroxidase of a sugar 3-phosphate D-glucopyranose AMK03_RS09670 dATP ectoine synthase: branched-chain amino acid lyase: hutH aminotransferase: (2S, 3S)-3- nucleoside 2- lysozyme: glucoamylase: phosphodiesterase/ phosphatase: phosphatase: acid lyase: maltose alpha-D- dTDP-4-amino-4,6- ribonucleotide synthase: adenine homospermidine β 3-oxohexanoyl-CoA amino acid muramoylpentapeptide beta-N- L-aspartate hydroxyacylglutathione AMK03_RS13440 AMK03_RS12515 epimerase: mce HPI: katG 6-phosphate AMK03_RS23785 -D-fructose 1,6- amino acid aminotransferase: urocanate 3-(4- AMK03_RS29595 methylaspartate deoxyribosyltransferase: AMK03_RS05615 AMK03_RS30365 [+ 4 isozymes] AMK03_RS21240 otsB glucosyltransferase: glucose-6- dideoxy-α-D-galactose UDP AMK03_RS18405 phosphoribosylformylglycinamidine phosphoribosyltransferase: aminotransferase: oxidase: hydrolase: gloB 3'-nucleotidase: an insertion [+ 2 isozymes] AMK03_RS01815 bisphosphate hydroxyphenyl) acetylglucosaminyltransferase: AMK03_RS08605 (2R)- predicted treS D-arabinofuranose AMK03_RS15660 ectoine synthase: acetyl-CoA C- AMK03_RS14200 aminotransferase: AMK03_RS14200 urocanate AMK03_RS27650 AMK03_RS08890 adenosylcobyrate ethanol trehalose-cis-keto- formaldehyde α-D-glucopyranose phosphate cyclo-ligase: AMK03_RS07545 4-methyl-2- pyruvate murG sequence IS30 with a 7,8-dihydrofolate ethylmalonyl-CoA dopamine ABC 5-phosphate class 1b ribonucleoside- N5-CAIR AMK03_RS04670 acetyltransferase: AMK03_RS14200 mono-mycolate a sugar a sugar ADP-α-D-glucose isomerase: pgi oxopentanoate hydratase: N-acetyl-D- a N-acetylmuramoyl- 3'-cmp integrated transposon 1-phosphate α-maltose AMK03_RS20815 3-methyl-2- 2-iminobutanoate transporter 3-deoxy-8- F6P diphosphate AIR AMP fructose- (3S)-3-methyl-2- AMK03_RS25805 4-hydroxyphenylpyruvate a 2-deoxy-D- a 2-hydroxy D-glucopyranose a glycogen dTDP-4-acetamido-4,6- 5-(carboxyamino)imidazole ectoine oxobutanoate 4-methyl-2- ditrans,octacis-undecaprenyldiphospho- UDP a nucleobase glucosamine pentapeptide- 2-iminosuccinate succinate glutathione of a sugar fructose- phosphooctulonate gln reductase: nrdF nrdE bisphosphate [+ 2 isozymes] oxopentanoate dioxygenase: hppD mesaconate ribosyl-base carboxylate dideoxy-α-D-galactose adenine and ribonucleotide mutase: purE 3-methyl-2- oxopentanoate urocanate N-acetyl-(N-acetylglucosaminyl)muramoyl- diphosphoundecaprenol bisphosphate maltokinase: treS synthase: kdsA mannose-1-phosphate UTP aldolase class I: γ vitamin B12-dependent adenosine butanoyl-CoA oxobutanoate 3-methyl-2- dehydrogenase: hydratase: homogentisate L-alanyl- -D-glutamyl-L-lysyl-D-alanine predicted aldolase class I: guanylyltransferase/ asp AMK03_RS18250 ribonucleotide salvage VI CAIR oxopentanoate AMK03_RS20140 AMK03_RS01790 KDO-8P mannose-6- CTP synthase: dehydrogenase: ABC AMK03_RS18250 reductase: acyl-CoA dehydrogenase: 2-oxobutanoate homogentisate α a sugar a sugar α α-maltose 1-phosphate phosphate isomerase: AMK03_RS10950 AMK03_RS20140 3-methylbutanoyl- 4-imidazolone- UDP-N-acetyl-α-D-glucosamine undecaprenyl-diphospho-N-acetylmuramoyl-L- D-threo-7,8- p-nitrophenyl- D-sedoheptulose a cytidine 1402 a 2-(all-trans- a monocarboxylic an N-hydroxy- 6-O- -mycolyl- phosphoenol transporter UDP- -D-galactose AMK03_RS08825 triose-phosphate AMK03_RS22395 1,2-dioxygenase: D-glucopyranose maltopentaose a homogalacturonan sn-glycerol meso-tartrate adenosine dehydrogenase: CoA 5-propanoate alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine β-D-galactoside 7-phosphate tyr trehalose 6- of a sugar biosynthesis AMK03_RS16915 phosphoribosylaminoimidazolesuccinocarboxamide (2S)-2- (S)-citramalate dihydroneopterin in 16S rRNA polyprenyl)phenol acid amide arylamine 3-phosphate pyruvate superpathway of pyrimidine isomerase: AMK03_RS04575 isobutanoyl-CoA AMK03_RS08775 L-proline degradation I pyrophosphate-- amidase: phosphate alpha-1,4-glucan-- CTP synthase: AMK03_RS11425 isovaleryl-CoA imidazolonepropionase: 16S rRNA arylamine N- tartrate D-mannopyranose dUDP adenosine kinase: AMK03_RS27965 methylbutanoyl- undecaprenyldiphospho- 2-polyprenylphenol L-glyceraldehyde aromatic amino trehalose- pyruvate UDP-α-D-glucose maltose-1-phosphate nucleobases salvage [+ 2 isozymes] dehydrogenase: AMK03_RS25825 4-maleyl- 4-alpha- fructose-6-phosphate (cytidine(1402)-2'-O) AMK03_RS27090 acetyltransferase: dehydrogenase: predicted 6-phosphate nucleoside AMK03_RS00715 phosphoribosylaminoimidazolesuccinocarboxamide CoA muramoylpentapeptide beta-N- pectate lyase: beta-glucosidase: 6-hydroxylase: ubiB 3-phosphate acid lyase: phosphatase: maltosyltransferase: α-Kdo triose-phosphate AMK03_RS22365 acetoacetate citramalate dihydroneopterin 1-phosphotransferase: -methyltransferase: amidase: AMK03_RS03095 AMK03_RS29955 kinase: pyk ABC β-D-fructose 1,6- UDP-glucose synthase: AMK03_RS17785 adenine salvage uracil crotonyl-CoA 2-methylbutanoyl- propanoyl-CoA acetylglucosaminyltransferase: glucanotransferase: AMK03_RS23940 AMK03_RS18980 reductase: mgrA a sugar a sugar AMK03_RS29615 phosphomannomutase: triphosphate hydrolase: AMP isomerase: N-formimino- maleylacetoacetate pro synthase: aldolase: folB AMK03_RS14880 rsmI a 3-(all-trans AMK03_RS01115 AMK03_RS01815 otsB transporter bisphosphate 4-epimerase uracil CoA 3-methylcrotonyl- murG malQ a 2'-O- an N- L-glyceraldehyde 2-hydroxy-3- α α 3-deoxy-manno- AMK03_RS16910 AMK03_RS02415 AMK03_RS10960 L-glutamate trifunctional AMK03_RS07230 D-sedoheptulose , '-trehalose pyruvate D-glyceraldehyde enoyl-CoA isomerase: maiA 1402 -polyprenyl) a monocarboxylate p-tyramine of a sugar GalE: galE α dUTP phosphoribosyltransferase: upp methylacrylyl-CoA dehydrogenase: CoA 1,7-bisphosphate methylcytidine acetoxyarylamine 3-phosphate oxosuccinate α a (1->4)- -D-glucan octulosonate α CDP SAICAR DHAP transcriptional benzene-1,2-diol 6- -mycolate [+ 2 isozymes] -D-mannose adenine UMP 3-phosphate hydratase: formimidoylglutamate maleylacetoacetate an unsaturated in 16S rRNA cytidylyltransferase: dUTP diphosphatase: dut AMK03_RS22385 acetyl/propionyl/ regulator/proline ditrans,octacis-undecaprenyldiphospho-N- a homogalacturonan 6-(hydroxymethyl) D-galactopyranose UDP-α-D-galactose 1,4-alpha-glucan 1-phosphate AMK03_RS07915 enoyl-CoA (E)-2- deiminase: isomerase: maiA acetate pyruvate UDP maltose maltotetraose pectate glycolaldehyde 4-nitrophenol AMK03_RS00700 class 1b ribonucleoside- UMP kinase: methylcrotonyl- β -7,8-dihydropterin nucleoside triphosphate adenylosuccinate hydratase: propanoyl dehydrogenase/L- acetyl-(N-acetyl- -D-glucosaminyl)muramoyl-L- oligosaccharide branching mannose-1-phosphate diphosphate type I enoyl-CoA methylcrotonoyl- CoA carboxylase AMK03_RS25830 4-fumaryl- F6P pyrophosphohydrolase: lyase: AMK03_RS11395 AMK03_RS09670 AMK03_RS01835 phosphate glutamate gamma- alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine protein GlgB: glgB CMP-Kdo guanylyltransferase/ reductase: nrdF nrdE CMP glyceraldehyde- hydratase: CoA acetoacetate mazG adenine deaminase: adenine UDP xanthine and xanthosine salvage subunit alpha: N-formyl- semialdehyde glucose-6- 1,4-alpha-glucan phosphorylation 3-phosphate AMK03_RS01835 enoyl-CoA enoyl-CoA acetate/propionate mannose-6- vitamin B12-dependent AICAR AMK03_RS17840 phosphoribosyltransferase: AMK03_RS11165 L-glutamate dehydrogenase: phosphate branching phosphate isomerase: dUMP dehydrogenase: hydratase: hydratase: family kinase: DNA combined with N,N'- a cytidine 1402 6,8- 2-hydroxy-2- ribonucleotide CMP adenine deaminase: ade AMK03_RS25350 phosphoglycerate (S)-3- [+ 2 isozymes] N-formylglutamate putA methanethiol O-acetyl-L- D-glucopyranose maltohexaose a β-D-galactoside hesperidin 4-guanidinobutyramide reduced riboflavin an arylamine a phosphate propionitrile isomerase: pgi bifunctional gap AMK03_RS07915 AMK03_RS01835 AMK03_RS17940 (S)-1-pyrroline- L-arginine exogenous DNA to form diacetylchitobiose an acyl phosphate protein GlgB: glgB AMK03_RS16915 (d)CMP kinase: xanthosine kinase: hydroxybutanoyl-CoA homoserine in 16S rRNA dihydroxypurine monoester methylpropanenitrile reductase: thymidylate synthase: adenine 3-methylglutaconyl- amidohydrolase: degradation VI a recombinational junction beta-N- 16S rRNA amidase: D-glucopyranose phosphoribosylaminoimidazolecarboxamide UTP 3-phospho- (S)-3-hydroxy- enoyl-CoA fumarate 5-carboxylate Holliday junction flavin reductase: arylamine N- xanthine alkaline nitrile nitrile a GlgE-glycogen GDP-α-D-mannose AMK03_RS08825 AMK03_RS14550 AMK03_RS00505 phosphoribosyltransferase: purine-nucleoside AMK03_RS18245 (S)-3- CoA AMK03_RS15010 propanoate (arginase 2 pathway) acetylhexosaminidase: 6-phosphate formyltransferase/IMP cyclohydrolase: purH isobutanoyl-CoA hydratase: 4-alpha- resolvase RuvX: ruvX alpha-L- (cytosine(1402)-N(4) AMK03_RS27090 acylphosphatase: AMK03_RS11370 acetyltransferase: dehydrogenase: hydratase: hydratase: CDP hypoxanthine AMK03_RS15660 13-DPG D-glycerate hydroxybutanoyl- beta-glucosidase: phosphatase: dCDP dTMP CTP synthase: phosphorylase: [+ 3 isozymes] O-acetylhomoserine AMK03_RS19225 )-methyltransferase amidase: AMK03_RS11895 AMK03_RS03095 xdhA xdhB nthB nthA nthB nthA CoA AMK03_RS07915 arg glucanotransferase: AMK03_RS18980 crossover junction rhamnosidase: [+ 2 isozymes] AMK03_RS21240 FAICAR AMK03_RS10950 AMK03_RS00995 (2S,3S)-3- aminocarboxypropyltransferase: [+ 2 isozymes] RsmH: rsmH AMK03_RS01115 dTMP kinase: xanthine malQ endodeoxyribonuclease AMK03_RS22210 an N 4 - an N- xanthine dehydrogeanse: glu arginase: AMK03_RS07935 N-acetyl-D- a carboxylate riboflavin urate an alcohol 2-hydroxyisobutyramide propionamide CTP hydroxy-2- L-glutamate-5- 1402 4-guanidinobutanoate AMK03_RS10825 bifunctional AMK03_RS22375 resolution of recombinationalRuvC: ruvC glucosamine methylcytidine acetylarylamine phosphoribosyltransferase: gpt AMP (S)-3-hydroxy- methylbutanoyl- HMG-CoA L-citrulline degradation rocF CTP phosphoribosylaminoimidazolecarboxamide xanthine 2-phospho- semialdehyde a non galactosylated hesperitin-7-O- β-L- in 16S rRNA dCTP dTDP hypoxanthine CoA D-galactopyranose junction formation phosphoribosyltransferase: gpt D-glycerate acetoacetyl-CoA isobutanoate L-ornithine maltopentaose maltose galactose acceptor β-D-glucoside rhamnopyranose formyltransferase/IMP cyclohydrolase: purH trifunctional acetate met of two intact strands phosphoribosyltransferase: hpt 3-hydroxyisobutyrate 2-methylacetoacetyl- phosphopyruvate L-citrulline transcriptional acetyl-CoA C- dehydrogenase: coenzyme A ornithine--oxo-acid hydratase: eno glycine cleavage regulator/proline IMP IMP XMP acetyltransferase: mmsB ornithine transaminase: reductase: acetoacetate dehydrogenase/L- dTTP phosphoenol AMK03_RS02840 carbamoyltransferase: AMK03_RS19985 (S)-methylmalonate- AMK03_RS22375 a [glycine-cleavage an N 10 - a plant soluble XLLG xyloglucan a pseudouridine 1915 a 5' triphospho- (S)-2-oxo-4- 3-amino-4- (2R,3S)-3- pyruvate AMK03_RS10145 glutamate gamma- D-glucopyranose maltotriose a glucan uroporphyrinogen-I 2-phosphoglycolate DHAP a D-hexose Fe 2+ n-butyronitrile 6 oligosaccharide hydroxy-4-carboxy- [+ 2 isozymes] semialdehyde 2-methylacetoacetyl- complex H protein] N glycine cleavage system semialdehyde L-glutamate-5- formyltetrahydrofolate phe heteroglycan in 23S rRNA [mRNA] hydroxybenzoate isopropylmalate pyruvate -[(R)-lipoyl]-L-lysine ornithine semialdehyde 23S rRNA RNA 5-ureidoimidazoline uroporphyrinogen phosphoglycolate arylamine N- 3-isopropylmalate methylglyoxal nitrile acetyl-CoA CoA aminomethyltransferase dehydrogenase: 2-oxo-4-hydroxy- glucokinase: kinase: pyk carbamoyltransferase: (pseudouridine(1915)- pyrophosphohydrolase: decarboxylase: phosphatase: acetyltransferase: dehydrogenase: synthase: hydratase: methylmalonate- GcvT: gcvT putA 4-alpha- beta-glucosidase: 4-alpha- 4-carboxy-5- AMK03_RS00895 bacterioferritin: bfr argF phenylalanine 4- N(3))-methyltransferase AMK03_RS21145 AMK03_RS00005 AMK03_RS11910 AMK03_RS03095 leuB AMK03_RS00900 nthB nthA semialdehyde acetyl-CoA C- glycine cleavage system carbamoyl glucanotransferase: AMK03_RS18980 glucanotransferase: ureidoimidazoline pyruvate aminomethyl- monooxygenase: RlmH: rlmH dehydrogenase: acyltransferase: aminomethyltransferase phosphate glu malQ malQ an N 3 - a 5'-phospho- decarboxylase: uraD 3-acetylamino-4- 4-methyl-2- D-hexose 6- (S)-3-amino-2- transferring AMK03_RS08755 coproporphyrinogen I glycolate methylglyoxal Fe 3+ butyramide AMK03_RS03805 AMK03_RS22380 GcvT: gcvT (S)-1-pyrroline- 1915 [mRNA] (S)-(+)-allantoin hydroxybenzoate oxopentanoate phosphate methylpropanoate glycine glutamine- methylpseudouridine [+ 3 isozymes] 5-carboxylate a plant soluble XXXG xyloglucan in 23S rRNA dehydrogenase: hydrolyzing 10 D-galactopyranose pyrroline-5- 4a-hydroxy-N - maltose heteroglycan oligosaccharide a glucan D-glucopyranose hydrogencarbonate acetyl-CoA propanoyl-CoA gcvP carbamoyl- tyr a [glycine-cleavage carboxylate formyltetrahydrofolate a [glycine-cleavage phosphate complex H protein] N 6 - reductase: complex H protein] N 6 synthase: L-methionine degradation aminomethyldihydrolipoyl- AMK03_RS15560 -dihydrolipoyl-L-lysine carA carB I (to L-homocysteine) L-lysine an (S-diacyl-sn- XLXG xyloglucan a long-linear α α-L- an L-1- D-glucopyranose a maltodextrin α-D-glucopyranose hydantoin 3-amino-4- β CDP- -D-glucose glyceryl)-L-cysteinyl- α uroporphyrinogen-III 2-heptaprenylphenol N-ethylmaleimide 5,6-dihydrouracil GDP- -L-fucose L-tartrate malonyl-CoA rhamnopyranose L-glutamate L-serine degradation carbamate met pro phosphatidylethanolamine oligosaccharide -D-glucan hydroxybenzaldehyde CDP- [apolipoprotein] uroporphyrinogen-III C- degradation II arylamine N- NAD-dependent GDP-L-fucose tartrate malonyl-CoA glucose 4,6- L-rhamnose methionine 2-polyprenylphenol dihydropyrimidinase: alkene reductase: 4-alpha- 4-alpha- methyltransferase: cobA acetyltransferase: dihydropyrimidine synthase: dehydrogenase: decarboxylase: mutarotase: adenosyltransferase: L-glutamine beta-glucosidase: hydA dehydratase: ser L-arginine glycine cleavage system apolipoprotein N- uroporphyrinogen-III C- 6-hydroxylase: ubiB AMK03_RS15420 AMK03_RS03990 rhaM glu L-threonine AMK03_RS01920 glucanotransferase: AMK03_RS18980 glucanotransferase: AMK03_RS03095 dehydrogenase AMK03_RS29955 AMK03_RS04655 rfbG threonine/serine degradation degradation I methyltransferase: cobA GDP-4-dehydro- β-L- aspartate/ aminomethyltransferase degradation II SAM acyltransferase: lnt malQ malQ 3-(all-trans-heptaprenyl) 3-acetylamino-4- subunit PreA: preA 2-hydroxy-3- CDP-4-dehydro-6- dehydratase: III (arginine GcvT: gcvT CO N-carbamoylglycine N-ethylsuccinimide α-D-rhamnose acetyl-CoA rhamnopyranose tyrosine/aromatic 2 precorrin-2 benzene-1,2-diol hydroxybenzaldehyde uracil oxosuccinate deoxy-α-D-glucose AMK03_RS18430 decarboxylase/ L-aspartate gln aminotransferase: thr an N-acyl-(S-diacyl- XXXG xyloglucan a short 1,4- agmatinase pathway) degradation I Asp-tRNA(Asn) a 2-acyl-1-lyso- a maltodextrin maltose D-galactopyranose AMK03_RS29595 2-aminoprop-[+ 2 isozymes] L-threonine 3- sn-glyceryl)-L- oligosaccharide α-D-glucan arg /Glu-tRNA(Gln) phosphatidylethanolamine aspartate 2-enoate dehydrogenase: cysteinyl-[lipoprotein] L-asparagine asp amidotransferase: transaminase: tdh L-phenylalanine SAH degradation I L-2-amino-3- aspartate/ gatC gatA gatB AMK03_RS09935 agmatine oxobutanoate degradation 4a-hydroxy-L- XXLG xyloglucan 3-phenyl-2- (R)-3- 5,6- dCTP tyrosine/aromatic [+ 6 isozymes] a generic D-glucopyranose maltotetraose 2-hydroxyisobutyramide L-iditol D-glucopyranose asp I (aerobic) adenosylhomocysteinase: erythro-5,6,7,8- 2-decaprenylphenol 4-hydroxybenzoate dihydrothymine 5-methylcytosine (R)-lactate asn glycine C- glu polynucleotide substrate oligosaccharide oxopropanoate hydroxybutanoate 2'-deoxycytidine 2-iminopropanoate agmatinase: aminotransferase: NAD-dependent AMK03_RS00160 tetrahydrobiopterin amidase: 4-hydroxybenzoate 3-hydroxybutyrate cytosine L-iditol 2- D-2-hydroxyacid xylose asparaginase: acetyltransferase: phe AMK03_RS29595 4a-hydroxytetrahydrobiopterin 2-polyprenylphenol dihydropyrimidine 5'-triphosphate aspartate speB 4-alpha- 4-hydroxyphenylpyruvate AMK03_RS27090 dehydrogenase: dehydrogenase: isomerase: AMK03_RS27240 AMK03_RS15290 phenylalanine 4- dehydratase: 3-monooxygenase: deaminase: dehydrogenase: deaminase: ammonia- agmatinase: aspartate S1/P1 nuclease: beta-glucosidase: dioxygenase: hppD 6-hydroxylase: ubiB amidase: dehydrogenase AMK03_RS23395 xylA asparaginase: L-homocysteine glucanotransferase: pobA AMK03_RS16070 AMK03_RS10210 AMK03_RS30800 AMK03_RS02655 lyase: aspA monooxygenase: transaminase: AMK03_RS20395 AMK03_RS18980 AMK03_RS01115 subunit PreA: preA speB gly AMK03_RS12665 malQ (2-hydroxyphenyl) 3-(all-trans-decaprenyl) thymine keto-L-sorbose keto-D-fructose AMK03_RS05840 AMK03_RS08755 AMK03_RS09935 (6R)-L-erythro-6,7- 2-hydroxy-2- protocatechuate acetoacetate thymine pyruvate dUTP L-glutamine acetate benzene-1,2-diol fumarate pyruvate putrescine asp tyr oxaloacetate dihydrobiopterin methylpropanoate degradation II XXXG xyloglucan D-galactopyranose a 5'-phosphomononucleotide a 5'-phosphooligonucleotide maltose maltotriose oligosaccharide L-glutamate L-alanine degradation I gln degradation IV glutamate synthase large 2,5-diamino-6-(5- 6-[1-hydroxyethyl]-7- 4a-hydroxy-N 10 - a 5-carboxymethylaminomethyluridine 34 a 2-deoxystreptamine a uridine 55 cytidine CTP 2-nonaprenylphenol an α-limit dextrin a kanamycin L-fuconate 5-fluorocytosine cellulose glu phospho-D-ribitylamino) Leu antibiotic ala subunit: gltB methyl-7,8-dihydropterin formyltetrahydrofolate in tRNA in tRNA nucleoside 2'-deoxycytidine NAD-glutamate pyrimidin-4(3H)-one 4a-hydroxytetrahydrobiopterin tRNA (cytidine(34) aminoglycoside 3-N- 4-alpha- tRNA aminoglycoside 3'- L-fuconate glu bifunctional 2-amino-4-hydroxy-6- cytosine endoglucanase: deaminase: 5'-triphosphate dehydrogenase: alanine -2'-O)- acetyltransferase: 2-polyprenylphenol glucanotransferase: phosphotransferase: diaminohydroxyphosphoribosylaminopyrimidine hydroxymethyldihydropteridine dehydratase: pseudouridine(55) dehydratase: deaminase: AMK03_RS09995 deaminase: dehydrogenase: ald methyltransferase: 6-hydroxylase: ubiB AMK03_RS15260 AMK03_RS07765 AMK03_RS21280 deaminase/5-amino-6-(5-phosphoribosylamino) diphosphokinase: folK AMK03_RS20395 aac(3) malQ synthase TruB: truB AMK03_RS27600 AMK03_RS10210 AMK03_RS02655 pyruvate 3 α [+ 2 isozymes] 2-oxoglutarate [1-(2-amino-7-methyl-4-oxo- 10 AMK03_RS15700 an N -acetyl-2- a -limit dextrin 55 a kanamycin 2-dehydro-3- uracil reductase RibD: ribD an N -formyl- 3-(all-trans-nonaprenyl) a pseudouridine 5-fluorouracil a cellodextrin UTP 5-amino-6-(5-phospho- 7,8-dihydro-3H-pteridin- a 5-carboxymethylaminomethyl- deoxystreptamine antibiotic with short branches 3'-phosphate deoxy-L-fuconate uridine 7,8-dihydrofolate 34 Leu benzene-1,2-diol in tRNA D-ribitylamino)uracil 6-yl)]ethyl diphosphate 2'-O-methyluridine in tRNA a reduced a reduced plastocyanin plastocyanin phosphate an oxidized an oxidized a branched- a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate phosphonate lipid II (meso an inorganic a sugar 6- a sugar 6- a sugar 6- an (aminoalkyl)phosphonate a basic a peptide a quaternary phosphate plastocyanin plastocyanin α-L- chain met 3+ α-L- microcin C a carbohydrate a carbohydrate a carbohydrate a carbohydrate a lipopolysaccharide phosphate phosphonate a polyamine a polyamine a tricarboxylate a tricarboxylate a tricarboxylate benzoate amino acid queuosine D-ribopyranose a glucan Fe diaminopimelate anion a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate L-arabinose L-arabinose phosphate phosphate phosphate phosphate phosphate 3-O-L-lysyl-1-O- an alkylphosphonate N-acetylneuraminate antibiotic ammonium a polysaccharide a lipopolysaccharide arabinopyranose amino acid chloramphenicol chromate rhamnopyranose containing) phosphatidylglycerol compound predicted predicted ABC predicted ABC predicted ABC predicted ABC predicted ABC predicted ABC predicted ABC predicted ABC predicted ABC predicted ABC predicted ABC predicted ABC predicted ABC predicted ABC predicted ABC predicted ABC ABC cytochrome cytochrome FtsW RS17595 RS05380 RS00915 RS17535 RS22195 RS22750 RS25960 RS19195 RS26050 RS26330 RS26680 RS19935 RS07840 RS28015 RS27275 RS27350 RS10270 RS28990 RS29210 transporter of transporter of transporter of transporter of transporter of transporter of transporter of transporter of transporter of transporter of transporter of transporter of transporter of transporter of RS29825 RS30745 RS31170 AraH AraG LptG efflux transporter of RS02610 RS04075 RS04775 RS15705 PhnC transporter of RS17815 RS03740 RS26755 RS00170 RS30585 RS17890 RS17885 RS18655 RS19270 MprF PhnC BenE RS20535 RS07480 RS07900 RS04695 RS28115 ChrA RS02530 SbmA SugE RS20725 RS29045 FhuB RhaS transporter c oxidase c oxidase a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a lipopolysaccharide phosphonate of phosphate α α an inorganic -L- an (aminoalkyl)phosphonate a branched- a peptide -L- a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate L-arabinose L-arabinose a sugar a sugar a sugar a basic N-acetylneuraminate D-ribopyranose a glucan 3+ lipid II (meso microcin C phosphate phosphate phosphonate a polyamine a polyamine a tricarboxylate a tricarboxylate a tricarboxylate arabinopyranose 3-O-L-lysyl-1-O- benzoate chain queuosine a quaternary met Fe rhamnopyranose a polysaccharide anion a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a carbohydrate a lipopolysaccharide an alkylphosphonate amino acid chloramphenicol chromate antibiotic diaminopimelate phosphate phosphate O O phosphonate phosphatidylglycerol amino acid ammonium a lipopolysaccharide 2 2 containing) phosphate compound H O H O 2 2 This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.