INDEX

Acetanilid, Effects of, on growth and blood morphology of rats . 34

-, Growth and blood morphology of rats receiving sodium bromide, caffeine and combinations with 43 Acetyicholine, Effect of acid on guinea pig ileum contracted by histamine and 253 Acid, Effect of, on guinea pig ileum contracted by acetylcholine and histamine 253 Alcohol injected intravenously : Further observations on effect of habituation on rate of metabolism 388

- metabolism, Effect of dinitrophenol on rate of 67 Alkylaryl thioureas, unsymmetrical, Relative hypnotic effects of some aryl ajid 19 Amidine and guanidine derivatives, Toxicity and glycaemic properties of number of 81 D’Amour, Fred E., and Gustavson, R. G. Biologic assay of “International Standard” estrin and of certain commercial preparations 472 Anaphylactic shock, canine, R#{244}le of histamine in 419 Anesthesia, morphine-sodium isoamylethylbarbiturate (sodium amytal) and ether, Antagonism between ephedrine sulphate and sodium isoamylethyl- barbiturate after intracisternal injection during 464

-‘ spinal, On duration of, in rabbit 264 Anaesthetic actions, Local, of certain pyrazoline and quinoline compounds. 199

- effects of some furan derivatives 394

- Threshold, and lethal concentrations of certain spinal anesthetics in rabbit 221 Anil and styryl quinoline compounds free from metals or metalloids, Chemo- therapeutic action on Sp. minus in mice by certain 56 Antrum, pyloric sphincter and duodenum, Effect of morphine sulphate and of dihydromorphinone hydrochloride upon, in non-anesthetized dogs 170 Argy, William P., Linegar, Charles R., and Dille, James M. Studies on barbiturates. XV. Excretion of barbital in normal and nephropathic subjects 258 Aryl and unsymmetrical alkylaryl thioureas, Relative hypnotic effects of some 19

Barbital, Excretion of, in normal and nephropathic subjects 258 Barbiturates, Addiction and tolerance to 245

-, On cause of delayed death in rat by isopropyl betabromallyl barbituric acid (nostal) and some related 289

-, Studies on. XV. Excretion of barbital in normal and nephropathic subjects 258 Barbituric acid derivatives, Comparative effects of, on isolated heart 333 483 484 INDEX deBeer, Edwin J., Buck, Johannes S., Ide, Walter S., and Hjort, Axel M. Relative hypnotic effects of some aryl and unsymmetrical alkylaryl thioureas 19 Bernheim, Mary L. C., and Bernheim, Frederick. Action of drugs on choline esterase of brain 427 Bernheim, Frederick, and Bernheim, Mary L. C. Action of drugs on choline esterase of brain 427 Bieter, Raymond N., McNearney, J. J., Cunningham, Raymond W., and Lenz, Oa. On duration of spinal anesthesia in rabbit 264

-, Cunningham, Raymond W., Lenz, Oa, and McNearney, J. J. Threshold anesthetic and lethal concentrations of certain spinal anesthetics in rabbit 221 Bismuth absorption, Rate of, in experimental animals following peroral administration 399 Blood morphology, Effects of acetanilid on growth and, of rats 34

- morphology, Growth and, of rats receiving sodium bromide, caffeine and combinations with acetanilid 43 Brain, Action of drugs on choline esterase of 427 Bronchial spasm induced by histamine, Bronchodilator actions in 152 Bronchodilator actions in bronchial spasm induced by histamine 152 Broom, W. A. Toxicity and glycaemic properties of number of amidine and guanidine derivatives 81 Browning, C. H., and Gulbransen, R. Chemotherapeutic action on Sp. minus in mice by certain anil and styryl quinoline compounds free from metals or metalloids 56 Brundage, John T., Gruber, Charles M., Thomas, J. Earl, and Crider, Joseph 0. Effect of morphine sulphate and of dihydromorphinone hydro- chloride upon antrum, pyloric sphincter and duodenum in non-anesthe- tized dogs 170 Buck, Johannes S., deBeer, Edwin J., Ide, Walter S., and Hjort, Axel M. relative hypnotic effects of some aryl and unsymmetrical alkylaryl thioureas 19

Caffeine, Site of action of, as respiratory stimulant 458

-, sodium bromide, and combinations with acetanilid, Growth and blood morphology of rats receiving 43 Cameron, W. M., and Tainter, M. L. Comparative actions of sympatho- mimetic compounds: Bronchodilator actions in bronchial spasm induced by histamine 152 Camp, W. J. R., and Higgins, J. A. Role of potassium in epinephrine action. 376 Canine anaphylactic shock, ROle of histamine in 419 Cannon, Paul R., and Hoick, Harald G. 0. On cause of delayed death in rat by isopropyl betabromallyl barbituric acid (nostal) and some related barbiturates 289 Chemotherapeutic action on Sp. minus in mice by certain anil and styryl quinoline compounds free from metals or metalloids 56 Chen, K. K., and Swanson, Edward E. Pharmacological action of coriamyrtin 410 INDEX 485

Chen, K. K., Swanson, Edward E., Kleiderer, E. C., and Clowes, G. H. A.

Ergotocin, ergometrine, ergostetrine and ergobasine . 74 Choline derivatives, Action of certain, on coronary flow 179

- esterase of brain, Action of drugs on 427 Circulatory changes, peripheral, New bloodless method for continuous recording of 6 Clarke, Geo E., and Marsh, Homer F. Rate of bismuth absorption in experi- mental animals following peroral administration 399 Clowes, G. H. A., Chen, K. K., Swanson, Edward E., and Kleiderer, E. C. Ergotocin, ergometrine, ergostetrine and ergobasine 74 Cocaine, Action of epinephrine, tyramine and ephedrine on small intestine of unanesthetized dog, before and following administration of 347 Coriamyrtin, Pharmacological action of 410

-, Studies on pharmacological action of 361 Coronary flow, Action of certain choline derivatives on 179

- ves8els, Dilation of, by certain organic extracts and drugs 98 Crider, Joseph 0., Gruber, Charles M., Thomas, J. Earl, and Brundage, John T. Effect of morphine sulphate and of dihydromorphinone hydrochlo- ride upon antrum, pyloric sphincter and duodenum in non-anesthetized dogs 170 Cunningham, Raymond W., Bieter, Raymond N., McNearney, J. J., and Lenz, Oa. On duration on spinal anesthesia in rabbit 264

-, Bieter, Raymond N., Lenz, Oa, and McNearney, J. J. Threshold anesthetic and lethal concentrations of certain spinal anesthetics in rabbit 221 Cutting, Windsor C., and Newman, Henry W. Alcohol injected intraven- ously. Further observations on effect of habituation on rate of metabol- ism 388

Dihydromorphinone hydrochloride, Effect of, and of morphine sulphate upon antrum, pyloric sphincter and duodenum in non-anesthetized dogs 170 Dille, James M., Argy, William P., and Linegar, Charles R. Studies on bar- biturates. XV. Excretion of barbital in normal and nephropathic subjects 258 Dinitrophenol, Effect of, on rate of alcohol metabolism 67 Dog, unanesthetized, Action of epinephrine, tyramine and ephedrine on small intestine of, before and following administration of cocaine 347 Dogs, non-anesthetized, Effect of morphine sulphate and of dihydromorphi- none hydrochloride upon antrum, pyloric sphincter and duodenum in.... 170 Duodenum, antruni and pyloric sphincter, Effect of morphine sulphate and of dihydromorphinone hydrochloride upon, in non-anesthetized dogs.... 170 Dragstedt, Carl A., and Mead, Franklin B. Role of histamine in canine anaphylactic shock 419 Drugs, Action of, on choline esterase of brain 427

-, Dilation of coronary vessels by certain organic extracts and 98

-, Studies on respiratory actions of, by means of phrenic potentials. I. Nicotine 310 486 INDEX

Ephedrine, Action of epinephrine, tyramine and, on small intestine of un anesthetized dog, before and following administration of cocaine 347

- sulphate, Antagonism between sodium isoamylethylbarbiturate (sodium amytal) and after intracisternal injection during morphine- sodium isoamylethylbarbiturate anesthesia and ether anesthesia 464 Epinephrine, Action of tyramine, ephedrine and, on small intestine of un- anesthetized dog, before and following administration of cocaine 347

- action, Role of potassium in 376 Ergobasine, ergotocin, ergometrine, ergostetrine 74 Ergometrine, ergotocin, ergostetrine and ergobasine 74 Ergostetrine, ergotocin, ergometrine and ergobasine 74 Ergotocin, ergometrine, ergostetrine and ergobasine 74 Esterase, choline, of brain, Action of drugs on 427

Estrin, Biologic assay of “International Standard, ‘ ‘ and of certain corn- rnercial preparations 472 Ether anesthesia, and morphine-sodium isoamylethylbarbiturate (sodium amytal) anesthesia, Antagonism between ephedrine sulphate and sodium isoarnylethylbarbiturate after intracisternal injection during 464

-, vinyl, Some pharmacological and toxicological properties of 274

Foetal gastrointestinal tract, human in vitro, Reactions of 324

Frogs, and turtles, Effect of certain saucy! derivatives on isolated hearts of . . 193 Furan derivatives, Anaesthetic effects of some 394

Gastrointestinal tract, human foetal, in vitro, Reactions of 324 Glycaemic properties and toxicity of number of amidine and guanidine derivatives Si Gold, Harry, and Modell, Walter. Studies on respiratory actions of drugs by means of phrenic potentials. I. Nicotine 310 Greene, Charles W. Dilation of coronary vessels by certain organic extracts and drugs 98 Gruber, Charles M. Action of epinephrine, tyramine and ephedrine on small intestine of unanesthetized dog, before and following administration of cocaine 347

-, Thomas, J. Earl, Crider, Joseph 0., and Brundage, John T. Effect of morphine sulphate and of dihydromorphinone hydrochloride upon an- trum, pyloric sphincter and duodenum in non-anesthetized dogs 170 Guanidine and amidine derivatives, Toxicity and glycaemic properties of number of 81 Guinea pig ileum contracted by acetyicholine and histamine, Effect of acid on 253 Gulbransen, R., and Browning, C. H. Chemotherapeutic action on Sp. minus in mice by certain anil and styryl quinoline compounds free from metals or metalloids 56 Gustavson, R. C., and D’Amour, Fred E. Biologic assay of “International Standard” estrin and of certain commercial preparations 472

Ham, A. M., and Robson, J. M. Comparative assay of oestrone. in rat and mouse 337 INDEX 487

Hambourger, W. E., and Smith, Paul K. Effects of acetanilid on growth and blood morphology of rats 34

-, and Smith, Paul K. Growth and blood morphology of rats receiving sodium bromide, caffeine and combinations with acetanilid 43 Heart, isolated, Comparative effects of barbituric acid derivatives on 333

Hearts, isolated, of frogs and turtles, Effect of certain salicyl derivatives on . . 193 Henderson, V. E., and Smith, A. H. R. Anaesthetic effects of some furan derivatives 394

Higgins, J. A., and Camp, W. J. R. Role of potassium in epinephrine action . 376 Histamine, Bronchodilator actions in bronchial spasm induced by 152

-, Effect of acid on guinea pig ileum contracted by acetylcholine and 253

-, ROle of, in canine anaphylactic shock 419 Hjort, Axel M., deBeer, Edwin J., Buck, Johannes S., and Ide, Walter S. Relative hypnotic effects of some aryl and unsymmetrical alkylaryl thioureas 19 Holck, Harald C. 0., and Cannon, Paul R. On cause of delayed death in rat by isopropyl betabromallyl barbituric acid (nostal) and some related barbiturates 289 Hormone, melanophore, of pituitary gland, Method for obtaining preparation of 1

-, thyrotropic, of pituitary gland and iodine metabolism 49 Hypnotic effects, Relative, of some aryl and unsymmetrical alkylaryl thioureas 19

Ide, Walter S., deBeer, Edwin J., Buck, Johannes S., and Hjort, Axel M. Relative hypnotic effects of some aryl and unsymmetrical alkylaryl thioureas 19 Ileum, guinea pig, contracted by acetyicholine and histamine, Effect of acid on 253 Intestine, small, of unanesthetized dog, Action of epinephrine, tyramine and ephedrine on, before and following administration of cocaine 347 Iodine metabolism, Thyrotropic hormone of pituitary gland and 49 Isenberger, Robert M., and Rice, James C. Antagonism between ephedrine sulphate and sodium isoamylethylbarbiturate (sodium amytal) after intracisternal injection during morphine-sodium isoamylethylbarbiturate (sodium amytal) anesthesia and ether anesthesia 464 Isopropyl betabromallyl barbituric acid (nostal) and some related barbitu- rates, On cause of delayed death in rat by 289 Ivie, Joseph McK., and Sachs, James W. Effect of acid on guinea pig ileum contracted by acetylcholine and histamine 253

Johnston, Robert L. Comparative effects of barbituric acid derivatives on isolated heart 333

-. Effect of certain salicyl derivatives on isolated hearts of frogs and turtles 193

Kleiderer, E. C., Chen, K. K., Swanson, Edward E., and Clowes, C. H. A. Ergotocin, ergometrine, ergostetrine and ergobasine 74 488 INDEX

Kniazuk, Michael, and Molitor, Hans. New bloodless method for continuous recording of peripheral circulatory changes 6

LeMessurier, D. H. Site of action of caffeine as respiratory stimulant 458 Lenz, Oa, Bieter, Raymond N., McNearney, J. J., and Cunningham, Ray- mond W. On duration of spinal anesthesia in rabbit 264

-, Bieter, Raymond N., Cunningham, Raymond W., and McNearney, J. J. Threshold anesthetic and lethal concentrations of certain spinal anesthetics in rabbit 221 Linegar, Charles R., Argy, William P., and Dille, James M. Studies on barbiturates. XV. Excretion of barbital in normal and nephropathic subjects 258

McCullagh, 13. Roy, Stimniel, Benjamin F., and Picha, Valerian. Thyro- tropic hormone of pituitary gland and iodine metabolism 49

McLachlin, A. D. Reactions of human foetal gastrointestinal tract in vitro . . 324 McNearney, J. J., Bieter, Raymond N., Cunningham, Raymond W., and Lenz, Oa. On duration of spinal anesthesia in rabbit 264

-, Bieter, Raymond N., Cunningham, Raymond W., and Lenz, Oa. Threshold anesthetic and lethal concentrations of certain spinal anes- thetics in rabbit 221 Maloney, A. H. Studies on pharmacological action of coriamyrtin 361 Marsh, Homer F., and Clarke, Ceo. E. Rate of bismuth absorption in experimental animals following peroral administration 399 Marshall, E. K., Jr., and Rosenfeld, Morris. Depression of respiration by oxygen 437 Mead, Franklin B., and Dragstedt, Carl A. Role of histamine in canine anaphylactic shock 419 Melanophore hormone of pituitary gland, Method for obtaining preparation of 1 Metabolism, alcohol, Effect of dinitrophenol on rate of 67

-, Alcohol injected intravenously : Further observations on effect of habituation on rate of 388

-, iodine, Thyrotropic hormone of pituitary gland and 49 Mice, Chemotherapeutic action on Sp. minus in, by certain anil and styryl quinoline compounds free from metals or met#{225}lloids 56 Modell, Walter, and Gold, Harry. Studies on respiratory actions of drugs by means of phrenic potentials. I. Nicotine 310 Molitor, Hans. Some pharmacological and toxicological properties of vinyl ether 274

-, and Kniazuk, Michael. New bloodless method for continuous record- ing of peripheral circulatory changes 6 Morphine-sodium isoamylethylbarbiturate (sodium amytal) anesthesia and ether anesthesia, Antagonism between ephedrine sulphate and sodium isoamylethylbarbiturate after intracisternal injection during 464 Morphine sulphate, Effect of, and of dihydromorphinone hydrochloride upon antrum, pyloric sphincter and duodenum in non-anesthetized dogs 170 Mouse, Comparative assay of oestrone in rat and 337 INDEX 489

Nephropathic subjects, normal and, Excretion of barbital in . 258 Newman, Henry W., and Cutting, Windsor C. Alcohol injected intra- venously : Further observations on effect of habituation on rate of metabolism 388

-, and Tainter, M. L. Effect of dinitrophenol on rate of alcohol metabolism 67 Nicotine : Studies on respiratory actions of drugs by means of phrenic potentials 310 Nostal (isopropyl betabromallyl barbituric acid) and some related barbi- turates, On cause of delayed death in rat by 289

Oestrone, Comparative assay of, in rat and mouse 337 Oxygen, Depression of respiration by 437

Pentobarbital-sodium and phenobarbital-sodium, Effects of daily adminis- tration and abrupt withdrawal of, in albino rat 245 Phenobarbital-sodiu.m and pentobarbital-sodium, Effects of daily ad.m.inis- tration and abrupt withdrawal of, in albino rat 245 Phrenic potentials, Studies on respiratory actions of drugs by means of. I. Nicotine 310 Picha, Valerian, Sthnmel, Benjamin F., and McCullagh, D. Roy. Thyro- tropic hormone of pituitary gland and iodine metabolism 49 Pituitary gland, Method for obtaining preparation of melanophore hormone of 1

-, Thyrotropic hormone of, and iodine metabolism 49 Potassium, Role of, in epinephrine action 376 Proceedings of the American Society for Pharmacology and Experimental Therapeutics, Incorporated, The Scientific 113 Excretion of barbital in normal and nephropathic subjects. By William P. Argy, Charles R. Linegar and James M. Dille 113

. Effects of deuterium oxid on respiratory and water exchanges of mice. By H. 0. Barbour and Jane Trace 113 Convulsant action of procaine. By R. Beutner, J. J. Prusmack and M. L.Miller 114 On duration of spinal anesthesia in rabbit. By Raymond N. Bieter, J. J. McNearney, Raymond W. Cunningham and Oa Lenz 114 Mechanism of morphine hyperglycemia. By R. C. Bodo, F. W. CoTui and A. E. Benaglia 115 Determination of barbiturates in blood and urine of experimental animals anesthetized with some barbituric acid derivatives. By John T. Brundage and Charles M. Gruber 116 Studies on toxicity and tolerance of nembutal in guinea pigs. By Em- mett B. Carmichael and Louis C. Posey 116 Action of certain yohombine derivatives on intestinal strips. By Nathan Chaset, F. F. Yonkman and A. G. Young 11 Ergotocin, ergometrine, ergostetrine and ergobasine. By K. K. Chen, Edward E. Swanson, E. C. Kleiderer and G H. A. Clowes 117 Differential response in reaction time in young women to pure caffeine and its equivalent in coffee. By R. H. Cheney 117 490 INDEX

Proceedings-Continued Mechanism of action of salines on intestinal motility. By Phoebe J. Crittenden and George B. Roth 118 Inexpensive laboratory timing device. By Norman A. David 118 Effects of carbarsone and related organic arsenicals on optic nerve of rabbits. By Norman A. David 118 Comparative tranquilizing effects and habit-forming tendencies of mor- phine and dilaudid on rats using Barlow’s method. By Norman A. David and Bernard J. Moore 118 Phenthiazine : Possible new urinary antiseptic. By Floyd DeEds, John 0. Thomas, C. W. Eddy and A. B. Stockton 118 Effect of barbiturates on rate of sedimentation of red blood corpuscles. By Ralph I. Dorfman and Clyde Brooks 119 Histamine factor in canine anaphylaxis. By Carl A. Dragstedt and Franklin B. Mead 120 Observation on emetic, respiratory and certain other actions of strophan- thidin in cat. By M. Dresbach 120 U. S. P. Standard digitalis powder. By C. W. Edmunds, Carl A. Moyer, James R. Shaw 120 Action of certain yohombine derivatives on frog heart. By Sidney Eigner, A. G. Young and F. F. Yonkman 121 Rate of disappearance of acacia from circulation, with new colorimetric blood acacia method. By George A. Emerson and Nilanth M. Phatak 121 Studies on calcium creosotate. By Edwin J. Fellows 122 Some actions of sodium salicylate on scorbutic guinea pigs. By Jacob J. Giardina and Harold N. Eta 122 Pituitrin anemia. By Alfred Gilman and Louis Goodman 123 Effect of intramuscular histidine on gastric physiology. By Louis Goodman, Philip Bearg and Alfred Gilman 123 Further studies on denervated kidney. By G. P. Grabfleld 124 Hormone of adrenal cortex. By Arthur Grollman and W. M. Firor 124 Study of toxic and anesthetic properties of ortal sodium in experimental animals. By Charles M. Gruber and John T. Brundage 124 Studies on persistence of action of digitalis and digitalis bodies. By H.B.Haag 125 Oral absorbable bismuth. By P. J. Hanzlik, A. J. Lehman and A. P. Richardson 126 Concentrations of adrenalin and pituitrin required to affect uterine motility, when they are administered by different methods. By 0. G. Harne and E. E. Painter 126 Effects of dilaudid and morphine on passage of barium meal in dog. By Ben K. Harned and Howard E. Curl 126 Action of some furan derivatives. By V. E. Henderson and A. H. R. Smith 127 Low plasma magnesium and high plasma potassium in essential epilepsy. By Arthur D. Hirschfelder and Victor G. Haury 127 Delayed death in relation to barbiturate structure. By Harold G. 0. Hoick and Paul R. Cannon 128 INDEX 491 Proceedings-Continued Blood sugar level following physostigmine and atropine. By M. Caroline Hrubetz 128 Study of seventeen Chinese drugs reputedly antipyretic. By Louise G. Hutchins 129 Further studies on guinea pig test of therapeutic potency of liver extracts. By Bernard M. Jacobson 129 New form of breathing mask for dogs. By D. E. Jackson 129 New type of Fick hollow spring manometer. By D. E. Jackson 130 Special dipping recorder. By D. E. Jackson 130 Action of convulsant barbiturate. By P. K. Knoefel 130 Studies on barbiturates. By Theodore Koppanyi, James M. Dille and Charles R. Linegar 130 Analysis of barbiturate-picrotoxin antagonism. By Theodore Koppanyi, Charles R. Linegar and James M. Dille 130 Effect of chlorinated ethylenes on perfused leg vessels of frog. By John C. Krantz, Jr., C. Jelleff Carr, Ruth Musser and Wm. G. Harne 131 Effect of morphine on activity of dog’s ileum at various distending pres- sures. By Hugo Krueger and Margaret Sumwalt 131 Effect of tissue enzymes on posterior pituitary extract. By Edward Larson 132 Physiological activity of posterior pituitary of blue and sperm whales.

By William T. McClosky, Lloyd C. Miller and D. H. Le Messurier. . . 132 Effects of l-m-hydroxyphenylethanolmethylamine hydrochloride on bronchial musculature of rabbits and guinea pigs. By A. R. McIntyre 133 Renal excretion of cocain in case of acute cocain poisoning. By A. R. McIntyre 133 Toxicity of cyclohexanol and cyclohexanol peroxide. By W. L. Menden- hall and A. J. Plummer 134 Effects of total plasmapheresis and plasma protein regeneration upon agglutiin titer of dogs. By J. B. Mitchell, Jr., J. N. Etteldorf and W. R. Amberson 134 Influence of age and sex on repeated administration of sodium pento- barbital to albino rats. By William M. Moir 135 Some undescribed pharmacological properties of bulbocapnine. By Hans Molitor 135 Quantitative colorimetric estimation of epinephrine by ammonium-o- iodoxybenzoate. By C. R. Moodey and C. D. Leake 136 Comparative study of various agents in chemotherapy of rat trichomo- niasis. By Phyllis M. Nelson 136 Pharmacologic action of alkyl rhodanates in relation to their chemical constitution and physico-chemical properties. By W. F. von Oettingen and W. Deichmann-GrObler 137 Relationship between intrathecal pressure, arterial blood pressure, and retinitis in man, and changes produced by amyl nitrite, nitroglycer- ine, and theophylline-ethylene-diamine. By W. D. Paul and J. A. Greene 137 Safety factors of certain common inhalation anesthetic agents. By S. A. Peoples, B. Abreu and C. D. Leake 138 492 INDEX

Proceedings-Continued Local anaesthetic action of certain aminoalcohol esters of 5-alkyl-2- furoic acid. By N. M. Phatek and C. D. Leake 138 Influence of secondary butyl alcohol on isolated heart. By Albert J. Plummer and Walter L. Mendenhall 138 Study of kinetics of choline esterase. By M. H. Roepke 139 Effect of anesthetics on fetal respiration. By Morris Rosenfeld and Franklin F. Snyder 139 Paraldehyde and benzyl alcohol on uterine activity. By George B. Roth and Howard F. Kane 140 Factors influencing sugar tolerance curve of hypophysectomized rats. By Leo T. Samuels and H. A. Ball 140 Treatment during withdrawal in opiate addicted monkey. By M. H. Seevers and R. T. Stormont 141 Opiate addiction in monkey. By M. H. Seevers 141 Spinal anesthesia in albino rat. By L. F. Shackell 141 Acute intraperitoneal toxicities of rotenone and mixed pyrethrins. By M. D. Shimkin, H. H. Anderson and C. D. Leake 142 Direct synthesis of l-erythrose from mesquite gum. By Milton Silverman 142 Some experimental anemias. By M. I. Smith and R. R. Stohlman 142 Anemia of deaminized casein. By M. I. Smith and E. F. Stohlman 142 Effects of sodium bicarbonate on antipyretic action and toxicity of acetanilid. By Paul K. Smith 142

Fixation of deuterium in mice. By Paul K. Smith and H. G. Barbour. . . 143 Iodine content of thyroid following chronic fluoride administration. By R. T. Stormont, F. L. Kozelka and M. H. Seevers 143 Pharmacological action of coriamyrtin. By Edward E. Swanson and K.K.Chen 144 Specificity relationships between types of arsenicals and types of

trypanosomes. By A. L. Tatum, M. L. Kuhs and C. C. Pfeiffer. . . 144 Some observations of pharmacology of ergostetrine (ergometrine, ergo- basine, ergotocin). By Marvin R. Thompson 145 Influence of rate of intravenous injection upon toxicity of digitalis and ouabain. By B. J. Vos and W. T. Dawson 145 Effect of pituitrin, water, theophylline and salyrgan on renal blood flow and creatinine clearance of unanesthetized rabbits and dogs. By A. M. Walker, C. F. Schmidt, K. A. Elsom and C. G. Johnston.... 146 Modified pigeon method for bioassay of anti-pernicious anemia liver extracts. By G. E. Wakerlin, H. D. Bruner and J. M. Kinsman 146 Improved method of measuring gaseous metabolism of small laboratory animals. By E. W. Wallace and F. C. Koch 147 Further studies dealing with sublingual absorption of drugs. By Robt. P. Walton 148 Some pharmacological actions of dicentrine methine hydrochloride. By R. A. Waud 148 Comparison of thio-analogue of nembutal to other short acting depress- ants. By H. W. Werner and T. W. Pratt 149 individual variation in susceptibility of normal dogs to ether and its

significance in “fixed dosage” methods of anesthesia. By R W. Whitehead and W. B. Draper 149 INDEX 493 Proceedings-Continued Difference between respiratory effects of morphine and compounds derived from it by substituting various chemical groups in 6-carbon position. By C. I. Wright 150 Further studies of chemotherapy of Yohimbic compounds. By Albert G. Young and Frederick Yonkman 150 Further studies on Yohimbine derivatives. By Frederick F. Yonkman and A. G. Young 151 Pyloric sphincter, antru.m and duodenum, Effect of morphine sulphate and of dihydromorphinone hydrochloride upon, in non-anesthetized dogs 170

Pyrazoline and quinoline compounds, Local anaesthetic actions of certain . . . . 199

Quinoline and pyrazoline compounds, Local anaesthetic actions of certain. . . 199

-, styryl and anil, compounds, free from metals or metalloids, Chemo- . therapeutic action on Sp. minus in mice by certain 56

Rabbit, On duration of spinal anesthesia in 264

-, Threshold anesthetic and lethal concentrations of certain spinal anesthetics in 221 Rat, albino, Effects of daily administration and abrupt withdrawal of phenobarbital-sodium and pentobarbital-sodium in 245

-, Comparative assay of oestron in mouse and 337

-, On cause of delayed death in, by isopropyl betabromallyl barbituric acid (nostal) and some related barbiturates 289 Rats, Effects of acetanilid on growth and blood morphology of 34

-, Growth and blood morphology of, receiving sodium bromide, caffeine and combinations with acetanilid 43 Respiration, Depression of, by oxygen 437 Respiratory actions of drugs, Studies on, by means of phrenic potentials. I. Nicotine 310

- stimulant, Site of action of caffeine as 458 Rice, James C, and Isenberger, Robert M. Antagonism between ephedrine sulphate and sodium isoamylethylbarbiturate (sodium amytal) after intracisternal injection during morphine-sodium isoamylethylbarbitu- rate (sodium amytal) anesthesia and ether anesthesia 464 Robson, J. M., and Ham, A. M. Comparative assay of oestrone in rat and mouse 337 Rosenfeld, Morris, and Marshall, E. K., Jr. Depression of respiration by oxygen 437

Sachs, James W., and Ivie, Joseph McK. Effect of acid on guinea pig ileum contracted by acetylcholine and histamine 253 Salicyl derivatives, Effect of certain, on isolated hearts of frogs and turtles.. 193 Sinha, H. K. Local anaesthetic actions of certain pyrazoline and quinoline compounds 199 Smith, A. H. R., and Henderson, V. E. Anaesthetic effects of some furan derivatives 394 Smith, Paul K., and Hambourger, W. E. Effects of acetanilid on growth and blood morphology of rats 34

-, and Hainbourger, W. E. Growth and blood morphology of rats receiv- ing sodium bromide, caffeine and combinations with acetanilid 43 494 INDEX

Sodium bromide, caffeine and combinations with acetanilid, Growth and blood morphology of rats receiving 43

- isoamylethylbarbiturate (sodium amytal), Antagonism between ephed- rine sulphate and, after intracisternal injection during morphine-sodium isoamylethylbarbiturate anesthesia and ether anesthesia 464 Spasm, bronchial, induced by histamine, Bronchodilator actions in 152 Spirillum minus, Chemotherapeutic action on, in mice by certain anil and styryl quinoline compounds free from metals or metalloids 56 Stanton, Eugene J. Addiction and tolerance to barbiturates? Effects of daily administration and abrupt withdrawal of phenobarbital-sodium and pentobarbital-sodium in albino rat 245 Stehle, R. L. Method for obtaining a preparation of melanophore hormone of pituitary gland 1 Stimmel, Benjamin F., McCullagh, D. Roy, and Picha, Valerian. Thyro- tropic hormone of pituitary gland and iodine metabolism 49 Styryl and anil quinoline compounds free from metals or metallQids, Chemo- therapeutic action on Sp. minus in mice by certain 56 Swanson, Edward E., and Chen, K. K. Pharmacological action of coriamyrtin 410

-, Chen, K. K., Kleiderer, E. C., and Clowes, G. H. A. Ergotocin, ergometrine, ergostetrine and ergobasine 74 Sympathomimetic compounds, Comparative actions of 152 V i”

Tainter, M. L., and Cameron, W. M. Comparative actions of sympatho- mimetic compounds : Bronchodilator actions in bronchial spasm induced by histamine 152

-‘ and Newman, H. W. Effect of dinitrophenol on rate of alcohol metabolism 67 Thioureas, aryl and unsymmetrical alkylaryl, Relative hypnotic effects of some 19 .“ Thomas, J. Earl, Gruber, Charles M., Crider, Joseph 0., and Brundage, John T. Effect of morphine sulphate and of dihydromorphinone hydrochlor- ide upon antrum, pyloric sphincter and duodenum in non-anesthetized dogs 170 Thyrotropic hormone of pituitary gland and iodine metabolism 49 Toxicity and glycaemic properties of number of amidine and guanidine derivatives 81 Turtles, and frogs, Effect of certain salicyl derivatives on isolated hearts of.. 193 Tyramine, Action of epinephrine, ephedrine and, on small intestine of un- anesthetized dog, before and following administration of cocaine 347

Vinyl ether, Some pharmacological and toxicological properties of 274

Wedd, Alfred M. Action of certain choline derivatives on coronary flow.... 179