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Chittaranjan National Cancer Institute (An Autonomous Body under Ministry of Health & Family Welfare, Govt. of India) 37, S. P. Mukherjee Road, Kolkata ‐ 700026 INDIA Tel: 033‐2476 5101/02/04/20/22; Fax: 91‐33‐2475 7606 E‐mail: [email protected]; Website: www.cnci.org.in II | CNCI Annual Report 2018‐19 Table of Contents Department Page No. Governing Body of CNCI V Structural Scheme of CNCI VI, VII Message from the Desk of the Director VIII Reports from the Research Wing Anticancer Drug Development & Chemotherapy 1 Cancer Chemoprevention 3 Environmental Carcinogenesis & Toxicology 6 Epidemiology & Bio‐Statistics 10 Immunoregulation and Immunodiagnostics 12 In‐Vitro Carcinogenesis and Cellular Chemotherapy 19 Neuroendocrinology and Experimental Hematology 24 Oncogene Regulation 26 Pathology and Cancer Screening 33 Receptor Biology and Tumor Metastasis 35 Signal Transduction & Biogenic Amines 42 Viral Associated Human Cancer 49 Academic Cell 51 Animal Care and Maintenance 53 Central Research Instrumentation Facility 56 Library 57 Clinical and Translational Research 59 Reports from the Hospital Wing Anaesthesia and ITU 63 ENT‐Head & Neck Oncology 64 Gynaecological Oncology 67 Medical Oncology 71 Medical Physics 73 Pathology 77 Radiation Oncology 80 Radiodiagnosis 84 Surgical Oncology 86 Pain and Palliative Care Unit 89 Medical Records 91 Dietetics 92 Division of Preventive Oncology 94 … Contd. next CNCI Annual Report 2018‐19 | III Table of Contents contd. ⋯ Annexures Running Projects i Publications vi Patents xi Gene Bank Submission xi Conference Presentations xii Awards or Special Achievements xix PhD awarded xxi DNB awarded xxii Conference/Symposium/Workshop organized xxii Administration of funds granted by Government of India & Government of West Bengal xxii for welfare of cancer patients Patient Care Facilities xxiii Staffs of General Administration, Accounts & Ancillary Departments xxiv IV | CNCI Annual Report 2018‐19 Governing Body Chittaranjan National Cancer Institute, Kolkata 1. Chairman Union Minister of Health & Family Welfare 2. Alternate Chairman Minister of Health & Family Welfare, Govt. of West Bengal 3. Member Secretary, Ministry of Health & Family Welfare, Govt. of India or his Nominee 4. Member Director General of Health Services, Directorate General of Health Services, Govt. of India, New Delhi 5. Member Financial Adviser, Ministry of Health & Family Welfare, Govt. of India, New Delhi 6. Member Secretary, Department of Health & Family Welfare, Govt. of West Bengal, Kolkata 7. Member Secretary, Finance Department, Govt. of West Bengal, Kolkata 8. Member Director of Health Services, Govt. of West Bengal, Kolkata 9. Member Director General or his Nominee, Indian Council of Medical Research, New Delhi 10. Member Director or his Nominee, Post Graduate Institute of Medical Education & Research, Chandigarh 11. Member Director or his Nominee, Institute of Post Graduate Medical Education & Research, Kolkata 12. Member Director, Saha Institute of Nuclear Physics, Kolkata 13. Member Director, School of Tropical Medicine, Kolkata 14. Member Nominee of the Department of Atomic Energy 15. Member Director, All India Institute of Hygiene & Public Health, Kolkata Amendment 16. Member Vice‐Chancellor, West Bengal University of Health Services (11th Meeting of the Governing Body, held on 26.04.2005) 17. Special Invitee Vice‐Chancellor, University of Calcutta, (12th Meeting of the Governing Body, held on 21.08.2010) 18. Member Chairman, Standing Finance Committee (10th Meeting of the Governing Body, held on 02.08.2003) 19. Member Two Experts in Biological Sciences related to Oncology ‐ one to be 20. nominated by the Union Health Minister and the other by the State Health Minister 21. Member Two Faculty Members of Chittaranjan National Cancer Institute 22. 23. Member By rotation to be nominated by the Standing Academic Committee 24. Member Director, Chittaranjan National Cancer Institute CNCI Annual Report 2018‐19 | V Chittaranjan National Cancer Institute DIRECTOR Dr. Jayanta Chakrabarti RESEARCH WING HOSPITAL WING Ruplal Nandy Memorial Cancer O.I.C.(R) M.S. & A.M.O. Research Centre, Chandannagar Scientific Departments Ancillary Depts./ Major Departments Ancillary Depts./ Units/Sections Units/Sections 1. Anticancer Drug 1. Central Research 1. Anesthesiology 1. Pain & Palliative Development Instrumentation HoD: Dr. S Ray Care Unit In‐Charge: Dr. C K Panda Facility 2. ENT‐Head & Neck HoD: Dr. R K Mandal 2. Cancer In‐Charge: Dr. C K Oncology 2. Dental Surgery Chemoprevention Panda HoD: Dr. A Dam In‐Charge: Dr. S N HoD: Dr. P. Saha 2. Academic Cell 3. Gynecological Basak 3. Environmental Academic Oncology Medical Records Carcinogenesis & 3. Coordinator: Dr. S HoD: R K Mandal HoD: Dr. S S Mandal Toxicology Mukherjee HoD: Dr. M Roy 4. Medical Oncology 4. Dietetics 3. Animal Care & HoD: Dr. K K Mukherjee Dietitian: Ms. P Das 4. Epidemiology & Maintenance 5. Paediatric Oncology Dutta Biostatistics HoD: Dr. A Rakshit HoD: Dr. R K Mandal / Section 5. Nursing Services 4. Library Section In‐Charge: Dr. K Asst. Nursing Supdt: Dr. S S Mandal ALIO: Mr. S K Mukherjee Ms. M Barui 5. Immuoregulation & Chakraborty & Immunodiagnostics 6. Medical Physics (Mukherjee) Mr. G Gorai HoD: Dr. D K Ray HoD: Dr. R Baral 6. Rehabilitation 5. Computer Section 7. Pathology Services 6. In Vitro Carcinogenesis & In‐Charge: Mr. K S Cellular Chemotherapy HoD: Dr. S Mitra Roychowdhury In‐Charge: Dr. C K Panda Mustafi 6. Maintenance 7. Neuroendocrinology 8. Radiation Oncology Department Experimental HoD: Dr. T Maji In‐Charge: Dr. A Hematology 9. Radiodiagnosis Rakshit In‐Charge: Dr. C K Panda HoD: Dr. S Mazumder 8. Oncogene Regulation 10. Surgical Oncology HoD: Dr. C K Panda HoD: Dr. J Chakrabarti 9. Pathology & Cancer 11. Dental Surgery Screening In‐Charge: Dr. S N Basak HoD: Dr. P Nath 12. Division of Preventive 10. Receptor Biology & Oncology Tumor Metastasis HoD: R K Mandal HoD: Dr. D Sinha 11. Signal Transduction & Biogenic Amines HoD: Dr. N Murmu 12. Viral Associated Human Cancer HoD: Dr. C K Panda 13. Clinical & Translational Research HoD: Dr. K K Mukherjee VI | CNCI Annual Report 2018‐19 Chittaranjan National Cancer Institute Administrative Set-up DIRECTOR ADMINISTRATION ACCOUNTS Senior Administrative Officer Accounts Officer Assistant Accounts Officer Office Superintendent ‐ Research Accountant Office Superintendent ‐ Hospital CNCI Annual Report 2018‐19 | VII Message from the Desk of the Director 1. Starting Diagnostic CT scans and also CT planning for Radiotherapy with the newly acquired CT Simulator. 2. Renovation of the Major operation Theatre Complex with inclusion of modern gadgets in anesthesia and Surgery. 3. Beautification of Hospital building premises, renovation of store, LED light illumination of wards with music system, Introduction of semi‐motorised beds in the wards from Swachhta Action Plan (SAP) funds released by the Govt. of India. 4. Empanelment of CNCI in Swasthya Sathi (state sponsored medical insurance scheme) for all modalities of Cancer treatment as an “A” category hospital. We have already treated more than 2000 patients with this scheme in the last eight Dr. Jayanta Chakrabarti, Director months. Chittaranjan National Cancer Institute 5. Rashtriya Arogya Nidhi (RAN) fund is poised to play a vital role in the treatment of amounting to 1.12 crore INR has been Cancer along with cancer research in the near utilized in the last year to provide free future. The Institute being already rich with the chemotherapy for patients with BPL status. legacy of Comprehensive Cancer care and In addition we have started to avail research in unison, is coming up with a state of chemotherapy at free of cost to those who the art Second Campus at Rajarhat, Kolkata which are financially deprived. would add 460 beds to the existing 200 beds in its 6. Introduction of quarterly Performance existing campus. Needless to reiterate that with a audit of clinical as well as supportive range of modern equipments in the field of cancer disciplines with an aim to improve and diagnosis and treatment it would be the most maintain the standard of patient care sought for destination for cancer treatment in this services. region. With the civil work nearly completed it is only a matter of few months that the major 7. We started an annual evaluation of the equipments and manpower would usher in a new scientific projects in the Research Division horizon in oncology. by External Experts to stimulate and propel the ongoing research works in the coveted In the last one year we have also strived to path of success. upgrade our existing campus, and give new dimensions to it. We have always believed in It’s our submission that the list is very small as “Service before Self” and each of us has compared to the wish list that would really have contributed to our motto with extreme zeal, an impact on the million lives affected with the passion and discipline. Few of our disease, but we would not let our determination accomplishments are as follows wane off at any cost to create survivor from a patient. VIII | CNCI Annual Report 2018‐19 CNCI Annual Report 2018‐19 | ix x | CNCI Annual Report 2018‐19 CNCI Annual Report 2018‐19 Research Wing Anticancer Drug Development and Chemotherapy In‐Charge Dr. Chinmay Kumar Panda Senior Assistant Director Grade Team minor groove binding and forms a stable complex. We are trying to utilize that finding Faculty in the current phase of our research focus. We Dr. Supratim Ghosh, Senior Scientific Officer II believe that simultaneous use of multiple