PDF Output of CLIC (Clustering by Inferred Co-Expression)

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PDF Output of CLIC (Clustering by Inferred Co-Expression) PDF Output of CLIC (clustering by inferred co-expression) Dataset: Num of genes in input gene set: 9 Total number of genes: 16493 CLIC PDF output has three sections: 1) Overview of Co-Expression Modules (CEMs) Heatmap shows pairwise correlations between all genes in the input query gene set. Red lines shows the partition of input genes into CEMs, ordered by CEM strength. Each row shows one gene, and the brightness of squares indicates its correlations with other genes. Gene symbols are shown at left side and on the top of the heatmap. 2) Details of each CEM and its expansion CEM+ Top panel shows the posterior selection probability (dataset weights) for top GEO series datasets. Bottom panel shows the CEM genes (blue rows) as well as expanded CEM+ genes (green rows). Each column is one GEO series dataset, sorted by their posterior probability of being selected. The brightness of squares indicates the gene's correlations with CEM genes in the corresponding dataset. CEM+ includes genes that co-express with CEM genes in high-weight datasets, measured by LLR score. 3) Details of each GEO series dataset and its expression profile: Top panel shows the detailed information (e.g. title, summary) for the GEO series dataset. Bottom panel shows the background distribution and the expression profile for CEM genes in this dataset. Overview of Co-Expression Modules (CEMs) with Dataset Weighting Scale of average Pearson correlations Num of Genes in Query Geneset: 9. Num of CEMs: 1. 0.0 0.2 0.4 0.6 0.8 1.0 Ruvbl1 Ruvbl2 Pfdn2 Skp2 Skp1a Cul1 Uri1 Stap1 Polr2e Ruvbl1 Ruvbl2 Pfdn2 CEM 1 (212 datasets) Skp2 Skp1a Cul1 Uri1 Stap1 Singletons Polr2e Symbol Num ofCEMGenes:6.Predicted1177.SelectedDatasets:212.Strength:1.4 CEM 1,Geneset"[C]URIcomplex",Page1 Ebna1bp2 Zmynd19 Snrnp40 Ranbp1 Rbmxl1 Nup107 Snrpd3 Snrpa1 Dctpp1 Rbm8a Stoml2 Ruvbl2 Ruvbl1 Rsl1d1 Psmg1 Magoh Polr2h C1qbp Nsun2 Nop16 Nup85 Nop56 Actl6a Ddx39 Ddx18 Apex1 Skp1a Prmt5 Gmps Gspt1 Rrp15 Prmt1 Pfdn2 Phf5a Pold2 Emg1 Cct6a Sf3a3 Cse1l Lsm2 Nhp2 Dkc1 Skp2 Cct7 Adsl Cct5 Cul1 Dis3 Lyar Gart 0.0 1.0 GSE13693 [9] GSE30160 [6] GSE20954 [14] Only showingfirst200datasets-Seetxtoutputforfulldetails. GSE12465 [14] GSE6998 [32] GSE13692 [8] GSE48204 [6] GSE6837 [8] GSE48790 [8] GSE18135 [18] GSE13874 [14] GSE13873 [27] GSE51483 [45] GSE27605 [8] GSE19885 [9] GSE47414 [18] GSE38831 [7] GSE7275 [8] GSE51628 [15] GSE26568 [6] GSE21299 [12] GSE7875 [16] GSE34215 [6] GSE28389 [20] GSE42548 [29] GSE19528 [8] GSE37029 [15] GSE11220 [44] GSE15872 [18] GSE11201 [18] GSE7705 [10] GSE6689 [12] GSE5671 [18] GSE12464 [23] GSE46091 [8] GSE15541 [12] GSE16874 [12] GSE5333 [16] GSE17316 [12] GSE32598 [11] GSE45619 [6] GSE46090 [12] GSE6065 [100] GSE8555 [8] GSE16925 [15] GSE7897 [60] GSE46797 [6] GSE31598 [12] GSE46606 [30] GSE11222 [42] GSE45941 [8] GSE22005 [23] GSE39449 [6] GSE7784 [12] GSE35366 [78] GSE54207 [9] GSE24789 [9] GSE6933 [15] GSE12498 [12] GSE23972 [6] GSE39233 [40] GSE24813 [10] GSE35998 [20] GSE27786 [20] GSE17617 [18] GSE5841 [6] GSE7050 [18] GSE46970 [15] GSE11356 [9] GSE48203 [9] GSE46724 [6] GSE22824 [24] GSE15161 [26] GSE21063 [24] GSE7683 [12] GSE33308 [10] GSE20987 [12] GSE27114 [6] GSE15624 [12] GSE27379 [6] GSE21491 [9] GSE16676 [11] GSE14012 [24] GSE21272 [44] GSE38463 [41] GSE21902 [31] GSE12454 [13] GSE40282 [6] GSE34723 [101] GSE16679 [8] GSE39458 [6] GSE20398 [30] GSE48397 [10] GSE21944 [6] GSE19732 [20] GSE8836 [56] GSE32386 [13] GSE11990 [20] GSE15808 [29] GSE41005 [8] GSE7012 [13] GSE10525 [18] GSE34839 [6] GSE20100 [15] GSE20391 [11] GSE10176 [6] GSE5976 [12] GSE56345 [9] GSE15772 [8] GSE9763 [20] GSE8025 [21] GSE19176 [10] GSE37907 [24] GSE18042 [18] GSE14406 [54] GSE35593 [6] GSE7759 [112] GSE21278 [48] GSE27092 [6] GSE6957 [12] GSE9297 [27] GSE16902 [21] GSE12982 [53] GSE2527 [6] GSE50813 [24] GSE23833 [12] GSE32986 [18] GSE6526 [16] GSE4288 [36] GSE46088 [8] GSE7460 [52] GSE26096 [10] GSE10273 [9] GSE8431 [12] GSE39469 [6] GSE46600 [44] GSE23845 [15] GSE17263 [6] GSE38304 [8] GSE10913 [6] GSE18224 [32] GSE28830 [9] GSE15871 [18] GSE33199 [64] GSE7342 [12] GSE17553 [16] GSE44261 [12] GSE10912 [6] GSE11973 [6] GSE25252 [10] GSE15155 [12] GSE21033 [12] GSE5861 [6] GSE22086 [6] CEM+ CEM GSE1479 [36] GSE13408 [14] GSE4535 [6] GSE9146 [27] GSE15267 [8] GSE29975 [6] 0.0 GSE21018 [6] GSE44162 [6] GSE1435 [27] Scale ofaveragePearsoncorrelations GSE4260 [6] GSE11766 [48] GSE6085 [43] GSE11572 [12] GSE14698 [12] GSE23040 [6] 0.2 GSE53946 [6] GSE50865 [12] GSE15121 [6] GSE24628 [16] GSE7324 [10] GSE12430 [21] GSE57543 [6] GSE36814 [20] GSE3126 [6] 0.4 GSE5236 [8] GSE28417 [12] GSE13225 [6] GSE10813 [12] GSE46185 [6] GSE27159 [8] GSE6030 [6] GSE33942 [12] GSE23600 [10] 0.6 GSE40230 [15] GSE34324 [12] GSE10871 [32] GSE23923 [8] GSE5309 [7] GSE43197 [27] GSE27378 [8] GSE9725 [16] GSE43381 [26] 0.8 GSE14753 [6] GSE12518 [6] GSE13149 [25] GSE49194 [14] Score 132.56 132.59 133.14 133.57 133.76 134.18 134.23 134.55 134.65 134.90 134.90 135.43 136.96 137.67 137.92 138.26 138.28 138.73 138.92 139.65 139.79 140.12 140.85 141.06 141.66 141.90 142.04 142.53 143.03 143.78 144.31 144.95 145.32 145.60 146.60 147.77 148.80 149.41 150.08 151.09 151.18 151.70 155.74 158.41 1.0 Notes Symbol Num ofCEMGenes:6.Predicted1177.SelectedDatasets:212.Strength:1.4 CEM 1,Geneset"[C]URIcomplex",Page2 Hnrnpab Tamm41 Cacybp Nup155 Nup133 Exosc3 Exosc2 Mrps22 Skiv2l2 Psmc4 Prpf31 Polr2d Nup43 Nop58 Aimp2 Nup54 Rpp30 Nup93 Pdap1 Dpy30 Cdca7 Pa2g4 Snrpb Mcm7 Mcm5 Hirip3 Alyref Gins1 Uchl5 Nol11 U2af1 Lsm3 Eif3g Uba2 Ddx1 Rpa2 Hells Ppil1 Exo1 Tipin Pes1 Fen1 Tcp1 Ftsj3 Drg1 Utp6 Nip7 Rfc5 Nifk Ncl 0.0 1.0 GSE13693 [9] GSE30160 [6] GSE20954 [14] Only showingfirst200datasets-Seetxtoutputforfulldetails. GSE12465 [14] GSE6998 [32] GSE13692 [8] GSE48204 [6] GSE6837 [8] GSE48790 [8] GSE18135 [18] GSE13874 [14] GSE13873 [27] GSE51483 [45] GSE27605 [8] GSE19885 [9] GSE47414 [18] GSE38831 [7] GSE7275 [8] GSE51628 [15] GSE26568 [6] GSE21299 [12] GSE7875 [16] GSE34215 [6] GSE28389 [20] GSE42548 [29] GSE19528 [8] GSE37029 [15] GSE11220 [44] GSE15872 [18] GSE11201 [18] GSE7705 [10] GSE6689 [12] GSE5671 [18] GSE12464 [23] GSE46091 [8] GSE15541 [12] GSE16874 [12] GSE5333 [16] GSE17316 [12] GSE32598 [11] GSE45619 [6] GSE46090 [12] GSE6065 [100] GSE8555 [8] GSE16925 [15] GSE7897 [60] GSE46797 [6] GSE31598 [12] GSE46606 [30] GSE11222 [42] GSE45941 [8] GSE22005 [23] GSE39449 [6] GSE7784 [12] GSE35366 [78] GSE54207 [9] GSE24789 [9] GSE6933 [15] GSE12498 [12] GSE23972 [6] GSE39233 [40] GSE24813 [10] GSE35998 [20] GSE27786 [20] GSE17617 [18] GSE5841 [6] GSE7050 [18] GSE46970 [15] GSE11356 [9] GSE48203 [9] GSE46724 [6] GSE22824 [24] GSE15161 [26] GSE21063 [24] GSE7683 [12] GSE33308 [10] GSE20987 [12] GSE27114 [6] GSE15624 [12] GSE27379 [6] GSE21491 [9] GSE16676 [11] GSE14012 [24] GSE21272 [44] GSE38463 [41] GSE21902 [31] GSE12454 [13] GSE40282 [6] GSE34723 [101] GSE16679 [8] GSE39458 [6] GSE20398 [30] GSE48397 [10] GSE21944 [6] GSE19732 [20] GSE8836 [56] GSE32386 [13] GSE11990 [20] GSE15808 [29] GSE41005 [8] GSE7012 [13] GSE10525 [18] GSE34839 [6] GSE20100 [15] GSE20391 [11] GSE10176 [6] GSE5976 [12] GSE56345 [9] GSE15772 [8] GSE9763 [20] GSE8025 [21] GSE19176 [10] GSE37907 [24] GSE18042 [18] GSE14406 [54] GSE35593 [6] GSE7759 [112] GSE21278 [48] GSE27092 [6] GSE6957 [12] GSE9297 [27] GSE16902 [21] GSE12982 [53] GSE2527 [6] GSE50813 [24] GSE23833 [12] GSE32986 [18] GSE6526 [16] GSE4288 [36] GSE46088 [8] GSE7460 [52] GSE26096 [10] GSE10273 [9] GSE8431 [12] GSE39469 [6] GSE46600 [44] GSE23845 [15] GSE17263 [6] GSE38304 [8] GSE10913 [6] GSE18224 [32] GSE28830 [9] GSE15871 [18] GSE33199 [64] GSE7342 [12] GSE17553 [16] GSE44261 [12] GSE10912 [6] GSE11973 [6] GSE25252 [10] GSE15155 [12] GSE21033 [12] GSE5861 [6] GSE22086 [6] CEM+ CEM GSE1479 [36] GSE13408 [14] GSE4535 [6] GSE9146 [27] GSE15267 [8] GSE29975 [6] 0.0 GSE21018 [6] GSE44162 [6] GSE1435 [27] Scale ofaveragePearsoncorrelations GSE4260 [6] GSE11766 [48] GSE6085 [43] GSE11572 [12] GSE14698 [12] GSE23040 [6] 0.2 GSE53946 [6] GSE50865 [12] GSE15121 [6] GSE24628 [16] GSE7324 [10] GSE12430 [21] GSE57543 [6] GSE36814 [20] GSE3126 [6] 0.4 GSE5236 [8] GSE28417 [12] GSE13225 [6] GSE10813 [12] GSE46185 [6] GSE27159 [8] GSE6030 [6] GSE33942 [12] GSE23600 [10] 0.6 GSE40230 [15] GSE34324 [12] GSE10871 [32] GSE23923 [8] GSE5309 [7] GSE43197 [27] GSE27378 [8] GSE9725 [16] GSE43381 [26] 0.8 GSE14753 [6] GSE12518 [6] GSE13149 [25] GSE49194 [14] Score 118.58 118.75 119.09 119.12 119.15 119.18 119.24 119.59 119.69 119.97 120.18 120.26 120.29 120.52 120.78 120.79 121.57 121.57 121.99 123.05 123.24 124.20 124.40 124.75 125.11 125.23 125.50 125.53 125.54 126.89 126.90 127.02 127.05 127.58 127.66 128.31 128.81 128.89 128.96 129.03 129.06 129.33 129.51 129.72 129.90 130.32 130.81 131.39 132.06 132.10 1.0 Notes Symbol Num ofCEMGenes:6.Predicted1177.SelectedDatasets:212.Strength:1.4 CEM 1,Geneset"[C]URIcomplex",Page3 Mybbp1a Psmd12 Ccdc58 Exosc7 Metap2 Cmss1 Mthfd1 Eef1e1 Grwd1 Cirh1a G3bp1 Gtf2e2 Polr2c Ncbp1 Nup35 Wdr74 Pbdc1 Rad51 Haus1 Eif2b3 Ddx27 Rpl7l1 Mcm2 Mcm6 Prim1 Ssrp1 Banf1 Yars2 Nme1 Ptcd3 Pwp1 Snrpf Msh2 Strap Nop9 Nudc Eif3d Pno1 Stip1 Rcc1 Orc6 Hn1l Ppat Cct2 Rfc4 Pfas Eif3l Ipo5 Aatf Atic 0.0 1.0 GSE13693 [9] GSE30160 [6] GSE20954 [14] Only showingfirst200datasets-Seetxtoutputforfulldetails. GSE12465 [14] GSE6998 [32] GSE13692 [8] GSE48204 [6] GSE6837 [8] GSE48790 [8] GSE18135 [18] GSE13874 [14] GSE13873 [27] GSE51483 [45] GSE27605 [8] GSE19885 [9] GSE47414 [18] GSE38831 [7] GSE7275 [8] GSE51628 [15] GSE26568 [6] GSE21299 [12] GSE7875 [16] GSE34215 [6] GSE28389 [20] GSE42548 [29] GSE19528
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