Ophthalmologic Techniques That Evaluate the Posterior Eye Segment

Total Page:16

File Type:pdf, Size:1020Kb

Ophthalmologic Techniques That Evaluate the Posterior Eye Segment MEDICAL POLICY POLICY TITLE OPHTHALMOLOGIC TECHNIQUES THAT EVALUATE THE POSTERIOR EYE SEGMENT POLICY NUMBER MP-2.056 Original Issue Date (Created): 8/9/2002 Most Recent Review Date (Revised): 7/31/2020 Effective Date: 12/1/2020 POLICY PRODUCT VARIATIONS DESCRIPTION/BACKGROUND RATIONALE DEFINITIONS BENEFIT VARIATIONS DISCLAIMER CODING INFORMATION REFERENCES POLICY HISTORY I. POLICY Analysis of the optic nerve (retinal nerve fiber layer) in the diagnosis and evaluation of patients with glaucoma or glaucoma suspects, multiple sclerosis, increased intracranial pressure, optic neuritis or optic nerve disorders may be considered medically necessary when using scanning laser ophthalmoscopy, scanning laser polarimetry, and optical coherence tomography. Analysis of the optic nerve (retinal nerve fiber layer) in the diagnosis and evaluation for all other indications is considered investigational. There is insufficient evidence to support a conclusion concerning the health outcomes or benefits associated with this procedure. The measurement of ocular blood flow, pulsatile ocular blood flow or blood flow velocity is considered investigational for all indications. There is insufficient evidence to support a conclusion concerning the health outcomes or benefits associated with this procedure. Cross-references: MP-2.028 Eye Care MP-2.085 Optical Coherence Tomography (OCT) of the Anterior Eye Segment MP-2.086 Retinal Telescreening for Diabetic Retinopathy II. PRODUCT VARIATIONS Top This policy is only applicable to certain programs and products administered by Capital BlueCross please see additional information below, and subject to benefit variations as discussed in Section VI below. FEP PPO- Refer to FEP Medical Policy Manual MP-9.03.06, Ophthalmologic Techniques for Evaluating Glaucoma. The FEP Medical Policy Manual can be found at: https://www.fepblue.org/benefit-plans/medical-policies-and-utilization-management- guidelines/medical-policies. Page 1 MEDICAL POLICY POLICY TITLE OPHTHALMOLOGIC TECHNIQUES THAT EVALUATE THE POSTERIOR E YE SEGMENT POLICY NUMBER MP-2.056 III. DESCRIPTION/BACKGROUND Top Several techniques have been developed to measure the thickness of the optic nerve/retinal nerve fiber layer (RNFL) as a method to diagnose and monitor glaucoma. Measurement of ocular blood flow is also being evaluated as a diagnostic and management tool for glaucoma. GLAUCOMA Glaucoma is characterized by degeneration of the optic nerve (optic disc). Elevated intraocular pressure (IOP) has long been thought to be the primary etiology, but the relation between IOP and optic nerve damage varies among patients, suggesting a multifactorial origin. For example, some patients with clearly elevated IOP will show no optic nerve damage, while others with marginal or no pressure elevation will show optic nerve damage. The association between glaucoma and other vascular disorders (e.g., diabetes, hypertension) suggests vascular factors may play a role in glaucoma. Specifically, it has been hypothesized that reductions in blood flow to the optic nerve may contribute to the visual field defects associated with glaucoma. Diagnosis and Management A comprehensive ophthalmologic exam is required for the diagnosis of glaucoma, but no single test is adequate to establish diagnosis. A comprehensive ophthalmologic examination includes assessment of the optic nerve, evaluation of visual fields, and measurement of ocular pressure. The presence of characteristic changes in the optic nerve or abnormalities in visual field, together with increased IOP, is sufficient for a definitive diagnosis. However, some patients will show ophthalmologic evidence of glaucoma with normal IOPs. These cases of normal tension glaucoma (NTG) are considered to be a type of primary open-angle glaucoma (POAG). Angle- closure glaucoma is another type of glaucoma associated with an increase in IOP. The increased IOP in angle-closure glaucoma arises from a reduction in aqueous outflow from the eye due to a closed angle in the anterior chamber. Diagnosis of angle-closure glaucoma is detailed in MP- 2.085. Conventional management of patients with glaucoma principally involves drug therapy to control elevated IOPs, and serial evaluation of the optic nerve, to follow disease progression. Standard methods of evaluation include careful direct examination of the optic nerve using ophthalmoscopy or stereophotography, or evaluation of visual fields. There is interest in developing more objective, reproducible techniques both to document optic nerve damage and to detect early changes in the optic nerve and retinal nerve fiber layer (RNFL) before the development of permanent visual field deficits. Specifically, evaluating changes in RNFL thickness has been investigated as a technique to diagnose and monitor glaucoma. However, IOP reduction is not effective in decreasing disease progression in a significant number of patients, and in patients with NTG, there is never an increase in IOP. It has been proposed that vascular dysregulation is a significant cause of damage to the RNFL, and there is interest in measuring ocular blood flow as both a diagnostic and a management tool for glaucoma. Changes in blood flow to the retina and choroid may be particularly relevant for diagnosis and treatment of NTG. A variety of techniques have been developed, as described below. (Note: This policy only addresses techniques related to the evaluation of the optic nerve, RNFL, or blood flow to the retina and choroid in patients with glaucoma.) Page 2 MEDICAL POLICY POLICY TITLE OPHTHALMOLOGIC TECHNIQUES THAT EVALUATE THE POSTERIOR EYE SEGMENT POLICY NUMBER MP-2.056 MULTIPLE SCLEROSIS This central nervous system disease involves an immune-mediated process, which directs an abnormal response from the body’s immune system to the central nervous system (the brain, spinal cord and optic nerves). In up to 20% of multiple sclerosis (MS) patients optic neuropathy may be the first demyelinating event. The most common type of involvement of the visual pathways is optic neuritis, which can result in varying degrees of visual loss. OPTIC NEURITIS Inflammation of the optic nerve. Often associated with MS this demyelinating and inflammatory condition occurs in 50% of MS patients and is the presenting feature in 15 to 20 percent of patients. Typically, painful, monocular vision loss evolves over hours to a few days. OCT can detect RNFL thinning in 85% of patients with this condition. PAPILLEDEMA Papilledema is optic disc swelling due to raised intracranial pressure. It occurs when raised intracranial pressure is transmitted to the optic nerve sheath. Typically bilateral, it is often discovered when individuals are evaluated for other symptoms. Visual symptoms are common, although rarely the presenting symptom. Diagnostic testing may include optical coherence tomography both to monitor swelling and to determine changes surrounding the retina. Left untreated vision loss can occur. Techniques to Evaluate the Optic Nerve and RNFL Confocal Scanning Laser Ophthalmoscopy Confocal scanning laser ophthalmoscopy (CSLO) is an image acquisition technique intended to improve the quality of the eye examination compared with standard ophthalmologic examination. A laser is scanned across the retina along with a detector system. Only a single spot on the retina is illuminated at any time, resulting in a high-contrast image of great reproducibility that can be used to estimate RNFL thickness. In addition, this technique does not require maximal mydriasis, which may be problematic in patients with glaucoma. The Heidelberg Retinal Tomograph is probably the most common example of this technology. Scanning Laser Polarimetry The RNFL is birefringent (or biorefractive), meaning that it causes a change in the state of polarization of a laser beam as it passes. A 780-nm diode laser is used to illuminate the optic nerve. The polarization state of the light emerging from the eye is then evaluated and correlated with RNFL thickness. Unlike CSLO, scanning laser polarimetry (SLP) can directly measure the thickness of the RNFL. GDx is a common SLP device. GDx contains a normative database and statistical software package that compare scan results with age-matched normal subjects of the same ethnic origin. The advantages of this system are that images can be obtained without pupil dilation and evaluation can be completed in 10 minutes. Current instruments have added enhanced and variable corneal compensation technology to account for corneal polarization. Page 3 MEDICAL POLICY POLICY TITLE OPHTHALMOLOGIC TECHNIQUES THAT EVALUATE THE POSTERIOR EYE SEGMENT POLICY NUMBER MP-2.056 Optical Coherence Tomography Optical coherence tomography (OCT) uses near-infrared light to provide direct cross-sectional measurement of the RNFL. The principles employed are similar to those used in B-mode ultrasound except light, not sound, is used to produce the 2-dimensional images. The light source can be directed into the eye through a conventional slit-lamp biomicroscope and focused onto the retina through a typical 78-diopter lens. This system requires dilation of the patient’s pupil. OCT analysis software is being developed to include optic nerve head parameters with spectral domain OCT, analysis of macular parameters, and hemodynamic parameters with Doppler OCT and OCT angiography. Pulsatile Ocular Blood Flow The pulsatile variation in ocular pressure results from the flow of blood into the eye during cardiac systole. Pulsatile ocular blood flow can thus be detected by the continuous
Recommended publications
  • An Unusual Presentation of Subfrontal Meningioma: a Case Report and Literature Review for Foster Kennedy Syndrome
    Intern Emerg Med (2011) 6:267–269 DOI 10.1007/s11739-010-0437-y CE - MEDICAL ILLUSTRATION An unusual presentation of subfrontal meningioma: a case report and literature review for Foster Kennedy syndrome Shahram Lotfipour • Kris Chiles • J. Akiva Kahn • Tareg Bey • Scott Rudkin Received: 17 December 2009 / Accepted: 13 July 2010 / Published online: 26 August 2010 Ó SIMI 2010 Introduction head trauma. She admitted to abusing crack cocaine for 13 years with her last use 4 months ago. She denied any Foster Kennedy syndrome, named after neurologist Robert trouble with ambulation, dizziness, and changes in hearing or Foster Kennedy (1884–1952), describes unilateral ipsilat- other alterations in sensation. She denied any suicidal or eral optic atrophy and contralateral papilledema from an homicidal ideation. The patient denied any auditory halluci- intracranial mass. This syndrome is unreliably associated nations, but did report that she had been experiencing with anosmia and ipsilateral proptosis [1]. It originates visual hallucinations and visual disturbances for at least from variety of intracranial pathologies, but most often a 6–8 months. She reported complete blindness in the left eye, subfrontal mass. We present a case of Foster Kennedy and shadow perception in her right for an unknown length of syndrome and review its etiology, pathology and incidence time. Her past medical history was notable for major in intracranial tumors. depression. The patient did not have a previous history of hallucinations or psychosis, and had never been hospitalized for psychiatric reasons. The patient was not on any medica- Case report tions, and was allergic to penicillin and codeine.
    [Show full text]
  • Annual Report Research Activity 2019
    Annual Report Research Activity 2019 Division of Clinical Neuroscience University of Oslo and Oslo University Hospital 0 Contents Oslo University Hospital and the University of Oslo .................................................................................... 4 From Division Director Eva Bjørstad ........................................................................................................... 4 Division of Clinical Neuroscience (NVR) Organizational Chart ..................................................................... 5 Department of Physical Medicine and Rehabilitation Rehabilitation after trauma....................................................................................................................... 6 Group Leader: Nada Andelic Painful musculoskeletal disorders .............................................................................................................. 9 Group Leader: Cecilie Røe Department of Refractory Epilepsy - National Centre for Epilepsy Complex epilepsy .................................................................................................................................... 11 Group Leader: Morten Lossius Department of Neurosurgery Neurovascular-Hydrocephalus Research Group ..................................................................................... 16 Group Leader: Per Kristian Eide Oslo Neurosurgical Outcome Study Group (ONOSG) ................................................................................. 19 Group Leaders: Eirik Helseth and Torstein
    [Show full text]
  • References Briskly Compared with the Fellow Eye
    LETTERS TO THE JOURNAL 367 frontal tumour. The optic atrophy is commonly felt to Sir, result from optic nerve compression and the contralateral Apraclonidine in the Management of Glaucomatocy­ 1.2 papilloedema from increased intracranial pressure. clitic crisis Another mechanism suggests that Foster Kennedy syn­ Glaucomatocyclitic cnSlS (Posner-Schlossman syn­ drome is due to bilateral direct optic nerve compression by drome) is a unilateral inflammation of the uveal tract in a midline basal mass or less commonly by long-standing which signs of an acute increase in intraocular pressure increased intracranial pressure without direct com­ predominate. As the aetiology is doubtful, numerous treat­ pression of either nerve.3 ments have been suggested, the main aim being to reduce Since the early cases of Foster Kennedy syndrome, the exceptionally high intraocular pressure which, left many cases have been reported in the literature caused by untreated, will cause permanent optic nerve damage. other tumours, especially meningiomas such as olfactory Apraclonidine hydrochloride I %, a clonidine deriva­ groove and sphenoid ridge meningiomas, with gliomas tive and a peripheral alpha-adrenergic agonist. was devel­ occasionally reported.�-7 To our knowledge, nasopharyn­ oped to lower intraocular pressure while minimising geal carcinoma is rarely reported in the literature as a systemic side effects. It has specificrecept or-binding and cause of Foster Kennedy syndrome. physico chemical properties that limit its access to the cen­ Other terms have been used in the literature to describe tral nervous system. In normal human volunteers it pro­ atypical cases of Foster Kennedy syndrome. 'Pseudo Fos­ duces a significant fall in intraocular pressure.
    [Show full text]
  • Fluorescein Angiography Reference Number: OC.UM.CP.0028 Coding Implications Last Review Date: 05/2020 Revision Log
    Clinical Policy: Fluorescein Angiography Reference Number: OC.UM.CP.0028 Coding Implications Last Review Date: 05/2020 Revision Log See Important Reminder at the end of this policy for important regulatory and legal information. Description Intravenous Fluorescein Angiography (IVFA) or fluorescent angiography is a technique for examining the circulation of the retina and choroid using a fluorescent dye and a specialized camera. It involves injection of sodium fluorescein into the systemic circulation, and then an angiogram is obtained by photographing the fluorescence emitted after illumination of the retina with blue light at a wavelength of 490 nanometers. This policy describes the medical necessity guidelines for fluorescein angiography. Policy/Criteria I. It is the policy of health plans affiliated with Envolve Vision, Inc.® that fluorescein angiography is medically necessary for the following indications: A. Initial evaluation of a patient with abnormal findings of the fundus / retina on ophthalmoscopy exam including one of the following: 1. Choroidal Neovascular Membranes (CNVM) 2. Lesions of the Retinal Pigment Epithelium (RPE) a. Serous Detachment of the RPE b. Tears or rips of the RPE c. Hemorrhagic detachment 3. Fibrovascular Disciform Scar 4. Vitreous Hemorrhage (patient presents with sudden loss of vision) 5. Drusen 6. Diabetic Retinopathy B. Evaluation of patient presenting with symptoms of sudden vision loss (especially central vision), blurred vision, distortion, etc., which may suggest a subretinal neovascularization and abnormal findings of the fundus / retina on ophthalmoscopy exam. C. Evaluation of patients with nonproliferative (background) and proliferative diabetic retinopathy without macular edema. Frequency is determined by disease progression and the treatment performed. Fluorescein angiography may be performed on the treated eye only at 6 weeks post-treatment and as often as every 8-12 weeks to assist in management of the retinopathy.
    [Show full text]
  • A Case of Foster Kennedy Syndrome in a Pregnant Lady Presenting with Unilateral Deterioration of Vision
    Mehmood A, et al., J Ophthalmic Clin Res 2021, 8: 076 DOI: 10.24966/OCR-8887/100076 HSOA Journal of Ophthalmology & Clinical Research Case Report last 4 months but over the last week before presentation, it had fallen A Case of Foster Kennedy precipitously to counting fingers. The vision in her right eye has also deteriorated over the preceding week together with frontal headaches Syndrome in a Pregnant Lady but not associated with nausea and vomiting. On examination, she was generally well, afebrile, alert, and oriented. Visual acuities were Presenting with Unilateral 6/18 in her right eye and counting fingers in the left eye not improving with pinhole or refraction. On slit lamp, anterior segment examination Deterioration of Vision of both eyes was unremarkable and fundal examination revealed Asif Mehmood1, Farooq Ul Abidin2* and Sharjeel Khan3 marked papilloedema on the right eye and optic atrophy on the left eye (Figure 1A,1B). There was no relative afferent pupillary defect, 1Consultant Ophthalmologist, Rehman medical institute, Peshawar, Pakistan no proptosis, no bruit, and extraocular movements of both the eyes 2Resident Ophthalmology, AFIO, Rawalpindi, Pakistan were full range. There were no other focal or generalized neurological 3Department of Ophthalmology, Dera Ismail Khan, Pakistan signs. Abstract Foster Kennedy syndrome is a rare neurological entity that includes ipsilateral optic atrophy, contralateral papilledema, and sometimes anosmia. The syndrome has been described in association with a variety of intracranial pathologies such as a large frontal lobe tumor, olfactory groove meningioma, or medial third sphenoidal wing meningioma. In this report, we present a case of sphenoidal wing meningioma with Foster Kennedy syndrome in a 25-year-old pregnant female.
    [Show full text]
  • Neuroradiology for Ophthalmologists
    Eye (2020) 34:1027–1038 https://doi.org/10.1038/s41433-019-0753-z REVIEW ARTICLE Neuroradiology for ophthalmologists 1 2 1 1,3,4,5,6,7 Bayan Al Othman ● Jared Raabe ● Ashwini Kini ● Andrew G. Lee Received: 3 June 2019 / Revised: 29 October 2019 / Accepted: 24 November 2019 / Published online: 2 January 2020 © The Author(s), under exclusive licence to The Royal College of Ophthalmologists 2020 Abstract This article will review the best approaches to neuroimaging for specific ophthalmologic conditions and discuss characteristic radiographic findings. A review of the current literature was performed to find recommendations for the best approaches and characteristic radiographic findings for various ophthalmologic conditions. Options for imaging continue to grow with modern advances in technology, and ophthalmologists should stay current on the various radiographic techniques available to them, focusing on their strengths and weaknesses for different clinical scenarios. Introduction Computed tomography (CT) 1234567890();,: 1234567890();,: Modern imaging technology continues to advance the CT imaging reconstructs a three-dimensional image made boundaries and increase the options available to physicians of many conventional x-ray images. The conventional x-ray with respect to neuroradiology. In ophthalmology, the most images are ordered in tomographic slices that have been common studies employed are computed tomography (CT) computerized so a viewer can scroll through the images, and magnetic resonance imaging (MRI). There are several analyzing sequential cross-sections [1]. Density is the pri- different types of protocols that provide unique advantages mary characteristic that determines image appearance on a and disadvantages depending on the clinical scenario. This CT scan. As with traditional x-rays, tissues appear on a grey article endeavours to review those options and discuss how scale ranging from white (i.e., hyperdense tissues such as they are best employed to evaluate a variety of specific bone) to black (i.e., hypodense materials such as air).
    [Show full text]
  • Astrocytic Tumors
    Neuro-ophthalmologic Examination of the Neurosurgical Patients Amgad Hanna, MD and Peter Savino, MD Departments of Neurosurgery and Ophthalmology Thomas Jefferson University December 2005 Agenda • Abnormal pupils: miosis and mydriasis • Trochlear N palsy • Fundi: NL and abnormal Abnormal pupils Miosis Not all constricted pupils are caused by carotid dissection V1 Postganglionic (3rd order) Horner’s Long Cil Nn Central (1st order) Horner’s Preganglionic (2nd order) Horner’s Causes of Horner’s Syndrome (usually have associated signs and symptoms) Cocaine NO Mydriasis response NE NE Blocks reuptake NE NE Of NE (90%) NO NE outside vesicles True Pseudo-Horner’s Horner’s (physiologic anisocoria) (MRI/A H/N – CT Chest) True Horner’s Hydroxyamphetamine test No response Mydriasis NE NE Release of NE from No NE NE NE inside vesicles synaptic vesicles NE Postganglionic Central or Horner’s Preganglionic Horner’s Physiologic Anisocoria Central or Preganglionic R Horner’s Postganglionic R Horner’s Case • 40 y/o Woman • C/O R swollen eyelid and H/A Upper lid (Muller’s m), lower lid (Lid retractis) Dim Light Post-Cocaine; True Horner’s Post-Hydroxyamphetamine; Postganglionic Horner’s Carotid Dissection Mydriasis Not all dilated pupils are caused by P Com aneurysms Parasympathetic and light reflex Posterior commissure III Inf div Short Cil Nn N to inf obl Physiologic anisocoria • Normal reaction to light • The size difference between both eyes remains the same with dim and bright light • 0.3 – 0.4 mm difference found in 50% of the normal population • Up
    [Show full text]
  • North American Neuro-Ophthalmology Society 42Nd Annual Meeting February 27 - March 3, 2016 JW Starr Pass Marriott • Tucson, Arizona
    North American Neuro-Ophthalmology Society 42nd Annual Meeting February 27 - March 3, 2016 JW Starr Pass Marriott • Tucson, Arizona Poster Session I: Clinical Highlights in Neuro-Ophthalmology Sunday, February 28, 2016 • 12:30 pm – 2:00 pm Authors will be standing by their posters during the following hours: Odd-Numbered Posters: 12:30 - 1:15 pm Even-Numbered Posters: 1:15 - 2:00 pm *Please note that all abstracts are published as submitted. Poster # Presenting Author Category: Disorders of the Anterior Visual Pathway (Retina, Optic Nerve, and Chiasm) 1 Compressive Optic Neuropathy from Salivary Gland Tumor of Sphenoid Sinus Nafiseh Hashemi 2 Unexpected Pathologic Diagnosis of Primary Dural B Cell Marginal Zone Lymphoma Alberto G. Distefano 3 Bilateral Epstein-Barr Virus Optic Neuritis in a Lung Transplant Patient Yen C. Hsia 4 Purtscher's Retinopathy as a Manifestation of Hemophagocytic Lymphohistiocytosis Dov B. Sebrow 5 Central Retinal Vein Occlusion, Paracentral Acute Middle Maculopathy, and Dov B. Sebrow Cilioretinal Vein Sparing with Acquired Shunt in a Patient with Antiphospholipid Syndrome and Cryoglobulinemia 6 A Case of Wyburn-Mason Syndrome Dae Hee Kim 7 Debulking Optic Nerve Gliomas for Disfiguring Proptosis: A Globe-Sparing Approach Faisal Y. Althekair by Lateral Orbitotomy Alone 8 Longitudinally Extensive Spinal Cord Lesion in Leber’s Hereditary Optic Neuropathy Faisal Y. Althekair Due to the M.3460A Mitochondrial DNA Mutation Longitudinally Extensive Spinal Cord Lesion in Leber’s Hereditary Optic Neuropathy due to the M.3460A Mitochondrial DNA Mutation 9 Growth of an Optic Disc Vascular Anomaly for Twelve Years John E. Carter 10 Retreatment with Ethambutol After Toxic Optic Neuropathy Marc A.
    [Show full text]
  • Tumors of the Meninges and Related Tissues: Meningiomas and Sarcomas
    CHAPTER 30 Tumors of the Meninges and Related Tissues: Meningiomas and Sarcomas Kimberly P. Cockerham, John S. Kennerdell, Joseph C. Maroon, and Ghassan K. Bejjani ANATOMY OFTHE MENINGES Associations Dura Mater Diagnosis Arachnoid Treatment Pia Mater Adjuvant Therapy MENINGIOMAS Clinical Characteristics by Location Histogenesis SARCOMAS OFTHE MENINGES AND BRAIN Incidence Chondrosarcoma Pathology Osteogenic Sarcoma Cytogenetics Primary Sarcoma of the Meninges and Brain Endocrinology Rhabdomyosarcoma ANATOMY OF THE MENINGES The meninges of the brain and spinal cord consist of three into several freely communicating compartments. They in- different layers: the dura mater, arachnoid (tela arach- clude the falx cerebri, the tentorium cerebelli, the falx cere- noidea), and pia mater. Considerable anatomic differences belli, and the diaphragma sellae. exist among these structures, and these differences influence The falx cerebri, so named because of its sickle-like form, the nature, location, and spread of tumors that arise from is a fixed, arched process that descends vertically in the them. longitudinal fissure between the cerebral hemispheres (Fig. 30.2). The tentorium cerebelli is an arched lamina that is DURA MATER elevated in its midportion and inclines downward toward its peripheral attachments on both sides. It covers the superior The dura mater, typically referred to as the dura, is a thick surface of the cerebellum and supports the occipital lobes membrane that is adjacent to the inner table of the skull and (Fig. 30.2). The falx cerebelli is a small triangular process acts both as the functional periosteum of the skull and the of dura mater that lies beneath the tentorium cerebelli in outermost membrane of the brain (Fig.
    [Show full text]
  • Foster Kennedy Syndrome Secondary to Oligodendroglioma
    Grand Rounds Vol 3 Speciality: Neurosurgery and oncology Article Type: Case report DOI: 10.1102/1470-5206.2003.0011 Abstract c 2003 e-MED Ltd Keywords Foster Kennedy syndrome secondary to Introduction Case report oligodendroglioma Discussion References Figure 1 S. M. Joshi, R. J. D. Hewitt and F. Afshar Figure 2 Department of Neurosurgery, The Royal London Hospital, Whitechapel, London, Figure 3 E1 1BB, UK Figure 4 Date accepted for publication 27 November 2003 Home Page Title Page Abstract JJ II Foster Kennedy syndrome (FKS) is rare. It is characterised by the presence of ipsilateral J I optic atrophy, contralateral papilloedema and ipsilateral anosmia. Since its first description in 1911, it has never been reported in oligodendroglioma. Here we discuss the first case of Go Back a patient with oligodendroglioma presenting with FKS. Full Screen Close Keywords Quit Foster Kennedy syndrome; oligodendroglioma. GR Introduction This case report represents the first description, in the literature, of an oligodendroglioma Abstract as the cause for Foster Kennedy syndrome (FKS). Keywords Introduction Case report Case report Discussion A 33-year-old, left handed gentleman was admitted in November 2002 with right eye vision References deterioration over 6 weeks and headaches which were exacerbated by coughing and pos- Figure 1 tural changes. Since 1996, he had a history of partial and generalised seizures secondary Figure 2 to an intracranial tumour. Previous magnetic resonance (MR) imaging had demonstrated a tumour with the appearance of a right subfrontal low-grade glioma (Fig. 1). The seizures Figure 3 commenced with an aura of odd epigastric sensations progressing to involuntary jerking of Figure 4 the left arm and leg with speech arrest, and the development of secondary generalisation characterised by tongue biting and incontinence.
    [Show full text]
  • Pituitary Adenomapresenting As the Foster-Kennedy Syndrome
    BritishJournal ofOphthalmology, 1992, 76, 117-119 117 Pituitary adenoma presenting as the Foster-Kennedy Br J Ophthalmol: first published as 10.1136/bjo.76.2.117 on 1 February 1992. Downloaded from syndrome Simon Ruben, John Elston, Richard Hayward Abstract had noted the presence of a right convergent A 27-year-old man presented to the casualty squint. department with visual failure. Clinically he On examination he was generally well, demonstrated the Foster-Kennedy syndrome. apyrexial, alert, and orientated. Visual acuities Computed tomography revealed a large space- were no perception of light on the right, hand occupying lesion which was subsequently movements on the left. There was a right relative shown to be a pituitary adenoma. The litera- afferent pupillary defect and fundal examination ture is reviewed and possible mechanisms of revealed optic atrophy on the right and marked the Foster-Kennedy syndrome are discussed. papilloedema on the left (Fig 1). There was venous congestion and absent venous pulsation in both eyes. In addition he had limitation of The Foster-Kennedy syndrome although not a lateral rectus function bilaterally, more pro- common phenomenon has been described in nounced on the right, and limitation of upward association with a wide variety of intracranial gaze. There were no other focal or generalised pathologies. We present here the first case of the neurological signs. He was therefore diagnosed Foster-Kennedy syndrome secondary to a as having the Foster-Kennedy syndrome. The Western Ophthalmic pituitary adenoma. Computed tomography (CT) scan of the brain Hospital, Marylebone showed a large lobulated mass arising in the Road, London midline from near the sella turcica and extending S Ruben Case report behind the dorsum sellae the anterior J Elston into part of A 27-year-old man presented to the casualty the posterior cranial fossa indenting the upper The National Hospital for department of an ophthalmic hospital complain- pons and filling the interpeduncular cysterns.
    [Show full text]
  • Fundus Photography Page 1 of 34
    Fundus Photography Page 1 of 34 Medical Policy Title: Fundus Photography Professional Institutional Original Effective Date: November 1, 2004 Original Effective Date: February 1,2005 Revision Date(s): August 1, 2005; Revision Date(s): August 1, 2005; August 30, 2006; March 14, 2011; August 30, 2006; March 14, 2011 July 25, 2012; March 13, 2013; July 25, 2012; March 13, 2013; December 11, 2013; April 14, 2015; December 11, 2013; April 14, 2015; October 1, 2015; April 13, 2016; October 1, 2015; April 13, 2016; October 1, 2016; April 28, 2017; October 1, 2016; April 28, 2017; October 1, 2017; November 7, 2018; October 1, 2017; November 7, 2018; August 15, 2019; October 1, 2020 August 15, 2019; October 1, 2020 Current Effective Date: August 15, 2019 Current Effective Date: August 15, 2019 State and Federal mandates and health plan member contract language, including specific provisions/exclusions, take precedence over Medical Policy and must be considered first in determining eligibility for coverage. To verify a member's benefits, contact Blue Cross and Blue Shield of Kansas Customer Service. The BCBSKS Medical Policies contained herein are for informational purposes and apply only to members who have health insurance through BCBSKS or who are covered by a self-insured group plan administered by BCBSKS. Medical Policy for FEP members is subject to FEP medical policy which may differ from BCBSKS Medical Policy. The medical policies do not constitute medical advice or medical care. Treating health care providers are independent contractors and are neither employees nor agents of Blue Cross and Blue Shield of Kansas and are solely responsible for diagnosis, treatment and medical advice.
    [Show full text]