Anti-ALOX15 monoclonal antibody, clone 4H9 (DCABH-1151) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Mouse monoclonal to 15 1

Antigen Description Converts to 15S-hydroperoxyeicosatetraenoic acid. Also acts on C-12 of arachidonate as well as on .

Immunogen Recombinant full length, Human 15 Lipoxygenase 1 produced in HEK293T cells (NP_001131).

Isotype IgG2b

Source/Host Mouse

Species Reactivity Rat, Dog, Human, Monkey

Clone 4H9

Purity Protein A purified

Purification Purified from Mouse ascites fluids by affinity chromatography

Conjugate Unconjugated

Applications WB, IHC-P, ICC/IF

Positive Control HEK293T cells transfected with pCMV6-ENTRY 15 Lipoxygenase 1 cDNA; HepG2, HeLa, A549, COS7, MDCK, PC12 and MCF7 cell extracts; Human breast, Human pancreas carcinoma, Human thyroid carcinoma, Human endometrium, Human endometrium adenocarcinoma, Human pros

Format Liquid

Size 100 μl

Buffer pH: 7.30; Preservative: 0.02% Sodium azide; Constituents: 48% PBS, 50% Glycerol, 1% BSA

Preservative 0.02% Sodium Azide

Storage store at -20°C. Avoid repeated freeze / thaw cycles.

Ship Shipped at 4°C.

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved GENE INFORMATION

Gene Name ALOX15 arachidonate 15-lipoxygenase [ Homo sapiens ]

Official Symbol ALOX15

Synonyms ALOX15; arachidonate 15-lipoxygenase; 15 LOX 1; 15-LOX; 15-lipooxygenase-1; arachidonate omega-6 lipoxygenase; 15LOX-1; 15-LOX-1;

Entrez Gene ID 246

Protein Refseq NP_001131

UniProt ID P16050

Chromosome Location 17p13.3

Pathway Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Synthesis, organism-specific biosystem; IL4-mediated signaling events, organism-specific biosystem; Linoleic acid metabolism, organism-specific biosystem; Linoleic acid metabolism, conserved biosystem; Metabolic pathways, organism- specific biosystem;

Function arachidonate 12-lipoxygenase activity; arachidonate 15-lipoxygenase activity; hepoxilin- activity; iron ion binding; lipoxygenase activity; metal ion binding; oxidoreductase activity;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved