Anti-ALOX15 monoclonal antibody, clone 4H9 (DCABH-1151) This product is for research use only and is not intended for diagnostic use. PRODUCT INFORMATION Product Overview Mouse monoclonal to 15 Lipoxygenase 1 Antigen Description Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid. Also acts on C-12 of arachidonate as well as on linoleic acid. Immunogen Recombinant full length, Human 15 Lipoxygenase 1 produced in HEK293T cells (NP_001131). Isotype IgG2b Source/Host Mouse Species Reactivity Rat, Dog, Human, Monkey Clone 4H9 Purity Protein A purified Purification Purified from Mouse ascites fluids by affinity chromatography Conjugate Unconjugated Applications WB, IHC-P, ICC/IF Positive Control HEK293T cells transfected with pCMV6-ENTRY 15 Lipoxygenase 1 cDNA; HepG2, HeLa, A549, COS7, MDCK, PC12 and MCF7 cell extracts; Human breast, Human pancreas carcinoma, Human thyroid carcinoma, Human endometrium, Human endometrium adenocarcinoma, Human pros Format Liquid Size 100 μl Buffer pH: 7.30; Preservative: 0.02% Sodium azide; Constituents: 48% PBS, 50% Glycerol, 1% BSA Preservative 0.02% Sodium Azide Storage store at -20°C. Avoid repeated freeze / thaw cycles. Ship Shipped at 4°C. 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved GENE INFORMATION Gene Name ALOX15 arachidonate 15-lipoxygenase [ Homo sapiens ] Official Symbol ALOX15 Synonyms ALOX15; arachidonate 15-lipoxygenase; 15 LOX 1; 15-LOX; 15-lipooxygenase-1; arachidonate omega-6 lipoxygenase; 15LOX-1; 15-LOX-1; Entrez Gene ID 246 Protein Refseq NP_001131 UniProt ID P16050 Chromosome Location 17p13.3 Pathway Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Eicosanoid Synthesis, organism-specific biosystem; IL4-mediated signaling events, organism-specific biosystem; Linoleic acid metabolism, organism-specific biosystem; Linoleic acid metabolism, conserved biosystem; Metabolic pathways, organism- specific biosystem; Function arachidonate 12-lipoxygenase activity; arachidonate 15-lipoxygenase activity; hepoxilin-epoxide hydrolase activity; iron ion binding; lipoxygenase activity; metal ion binding; oxidoreductase activity; 45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected] Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved.