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Fetal Alcohol Forum Issue 6

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Fetal Alcohol Forum Issue 6 December 2011 Issue 6 The International Medical e-Network devoted to Fetal Alcohol Spectrum Disorders NOFAS-UK National Organisation for Fetal Alcohol Syndrome – UK 165 Beaufort Park, London NW11 6DA, England Tel: 020 8458 5951, Fax: 020 8209 3296 Helpline 08 700 333 700 Email: [email protected] Website: www.nofas-uk.org Charity No. 1101935 Issue 6 – December 2011 INTRODUCTION As the FETAL ALCOHOL FORUM has gained more recognition, so too has the issue of Fetal Alcohol Spectrum Disorder (FASD). Millions of people around the world live with this challenging disorder. We hope, by putting FASD research on the international medical radar, support for all the people affected will increase and education will help decrease the number of babies born with alcohol related brain damage. In this issue you will find abstracts of FASD studies from 28 countries along Susan Fleisher with a selection of articles, full studies and FASD news. As always, we begin with original articles contributed by leading FASD experts: Albert E. Chudley, MD, FRCPC, FCCMG, Canada; Piyadasa W. Kodituwakku, PhD, USA; Carmen Rasmussen, PhD, Canada and researcher Leigh Anne Davies who worked closely with Professor Denis Viljoen in South Africa. In the 2nd section you will find abstracts of studies linking alcohol to DNA damage, investigating gene interaction and bio-markers, new studies on low level and moderate drinking, the effects of early postnatal ethanol exposure, prevalence studies in Ireland and Australia recording higher alcohol consumption in pregnancy than previously estimated, predicting a rise in FASD births, and thought provoking articles by FASD legal experts from ‘THE JOURNAL OF PSYCHIATRY & LAW’. Italy and Spain, in the absence of epidemiological studies, did surveys to assess the knowledge and confidence of medical professionals in diagnosing FAS and FASD. Study #99 in the Ukraine suggests that ‘partner based’ interventions could make a significant contribution to FASD prevention. (Contact NOFAS-UK for our prevention support “Fathers Leaflet”) Several animal studies investigate antioxidant agents with neuro-protective properties that could ameliorate some ethanol damage. The debate about the benefits of alcohol in pregnancy is also represented I invite you to review the articles from our experts and the abstracts of the enlightening studies that follow. In the past 6 months, since the last publication of the FETAL ALCOHOL FORUM, we have located FASD studies in 28 countries. The United States produced the most FASD research in the world with 73 studies. However, based on population, (US - 307,006,550 and Canada – 34,108,752 in 12/2011), the 31 studies produced by Canada, per capita, is 9 times as many as the US. www.nofas-uk.org 2 NOTE: FASD studies worldwide during the past 6 months. USA 73 CANADA 31 AUSTRALIA 10 SPAIN 7 DENMARK 5 ITALY 5 BRAZIL 3 SOUTH AFRICA 3 SOUTH KOREA 4 CHINA 3 GERMANY 3 IRAN 2 THE NETHERLANDS 3 FINLAND 2 RUSSIA 2 SWITZERLAND 2 UNTIED KINGDOM 2 ARGENTINA 1 BELGIUM 1 CôTE D’IVOIRE 1 ISRAEL 1 JAPAN 1 NORWAY 1 POLAND 1 PORTUGAL 1 REPUBLIC OF IRELAND 1 SWEDEN 1 TURKEY 1 Please let us have your feedback at [email protected]. You can download all 6 issues of the FETAL ALCOHOL FORUM from our website: www.nofas-uk.org. To be added to our mailing list click here. Please also let us know if you would like to make a contribution to the next issue of the FETAL ALCOHOL FORUM. Thank you for your interest in the world of Fetal Alcohol Spectrum Disorders and beyond. Susan Fleisher Publisher Vandana Alimchandani Editor/Technical Supervisor Elizabeth Mitchell Associate Editor Leigh-Anne Davies Researcher www.nofas-uk.org 3 TABLE OF CONTENTS *In the interest of brevity, Fetal Alcohol Spectrum Disorder has been abbreviated to FASD ORIGINAL ARTICLES BY FASD EXPERTS RESEARCH ABSTRACTS ARTICLE ABSTRACTS NEWS AND PRESS FULL STUDIES www.nofas-uk.org 4 ORIGINAL ARTICLES BY FASD EXPERTS I. COMMENTARY – A PERSONAL REFLECTION: FETAL ALCHOL SPECTRUM DISORDER- WHY IS IT STILL WITH US? Albert E. Chudley, MD, FRCPC, FCCMG II. SLOW INFORMATION PROCESSING UNDERLIES COGNITIVE BEHAVIORAL DIFFICULTIES IN CHILDREN WITH FASD Piyadasa W. Kodituwakku, PhD. III. FASD: PERSONAL EXPERIENCE, RESEARCH, AND INTERVENTIONS Carmen Rasmussen, PhD IV. TIME TO REFLECT~ FETAL ALCOHOL SPECTRUM DISORDER (FASD): NORTHERN CAPE PROVINCE OF SOUTH AFRICA Leigh-Anne Davies, Doctoral Scholar Back to Table of Contents www.nofas-uk.org 5 RESEARCH ABSTRACTS 1. GLYCOSYLATION DEFECTS UNDERLYING FETAL ALCOHOL SPECTRUM DISORDER: A NOVEL PATHOGENETIC MODEL : "WHEN THE WINE GOES IN, STRANGE THINGS COME OUT" - S.T. COLERIDGE, THE PICCOLOMINI Binkhorst M, Wortmann SB, Funke S, Kozicz T, Wevers RA, Morava E. Publication – PubMed 2nd December 2011 2. CORTICAL THICKNESS IN FETAL ALCOHOL SYNDROME AND ATTENTION DEFICIT DISORDER Fernández-Jaén A, Fernández-Mayoralas DM, Quiñones Tapia D, Calleja-Pérez B, García- Segura JM, Arribas SL, Muñoz Jareño N. Publication – PubMed December 2011 3. SCREENING AMERICAN INDIAN/ALASKA NATIVES FOR ALCOHOL ABUSE AND DEPENDENCE IN MEDICAL SETTINGS Abbott PJ Publication – PubMed December 2011 4. VALIDATION OF THE ALCOHOL USE MODULE FROM A MULTIDIMENSIONAL PRENATAL PSYCHOSOCIAL RISK SCREENING INSTRUMENT Harrison PA, Godecker A, Sidebottom AC. Publication – PubMed 26th November 2011 5. SUBSTANCE EXPOSURE IN UTERO AND DEVELOPMENTAL CONSEQUENCES IN ADOLESCENCE: A SYSTEMATIC REVIEW Irner TB. Publication – PubMed 25th November 2011 6. LOBELINE ATTENUATES NEONATAL ETHANOL-MEDIATED CHANGES IN HYPERACTIVITY AND DOPAMINE TRANSPORTER FUNCTION IN THE PREFRONTAL CORTEX IN RATS Smith AM, Wellmann KA, Lundblad TM, Carter L, Barron S, Dwoskin LP. Publication – PubMed December 2011 7. VALIDITY OF A MATERNAL ALCOHOL CONSUMPTION QUESTIONNAIRE IN DETECTING PRENATAL EXPOSURE Manich A, Velasco M, Joya X, García-Lara NR, Pichini S, Vall O, García-Algar O. Publication – PubMed 19th November 2011 8. ALONG-TRACT STATISTICS ALLOW FOR ENHANCED TRACTOGRAPHY ANALYSIS Colby JB, Soderberg L, Lebel C, Dinov ID, Thompson PM, Sowell ER. Publication – PubMed 9th November 2011 www.nofas-uk.org 6 9. MECONIUM TESTING FOR FATTY ACID ETHYL ESTERS: A 2011 STATUS REPORT Stuart MacLeod, Gideon Koren Publication – Journal of Population Therapeutics and Clinical Pharmacology 5th November 2011 10. UNDERSTANDING STANDARD DRINKS AND DRINKING GUIDELINES Kerr WC, Stockwell T. Publication – PubMed 3rd November 2011 11. DIFFERENTIAL EFFECTS OF ETHANOL ON C-JUN N-TERMINAL KINASE, 14-3-3 PROTEINS, AND BAX IN POSTNATAL DAY 4 AND POSTNATAL DAY 7 RAT CEREBELLUM Marieta Barrow Heaton, Michael Paiva, Stacey Kubovic, Alexandra Kotler, Jonathan Rogozinski, Eric Swanson, Vladimir Madorsky, Michelle Posados Publication – ScienceDirect 3rd November 2011 12. TRENDS IN HEALTH-RELATED BEHAVIORAL RISK FACTORS AMONG PREGNANT WOMEN IN THE UNITED STATES: 2001-2009 Zhao G, Ford ES, Tsai J, Li C, Ahluwalia IB, Pearson WS, Balluz LS, Croft JB. Publication – PubMed 2nd November 2011 13. EGO-DYSTONIC PREGNANCY AND PRENATAL CONSUMPTION OF ALCOHOL AMONG FIRST-TIME MOTHERS O'Brien PL; The Centers for the Prevention of Child Neglect Publication – PubMed 2nd November 2011 14. CRITIQUING FETAL ALCOHOL SYNDROME HEALTH COMMUNICATION CAMPAIGNS TARGETED TO AMERICAN INDIANS Rentner TL, Dixon LD, Lengel L. Publication – PubMed 1st November 2011 15. EFFECT OF ALCOHOL CONSUMPTION IN PRENATAL LIFE, CHILDHOOD, AND ADOLESCENCE ON CHILD DEVELOPMENT Foltran F, Gregori D, Franchin L, Verduci E, Giovannini M. Publication – PubMed November 2011 16. ETHANOL CAUSES THE REDISTRIBUTION OF L1 CELL ADHESION MOLECULE IN LIPID RAFTS Tang N, Farah B, He M, Fox S, Malouf A, Littner Y, Bearer CF. Publication – PubMed November 2011 17. COMPREHENSIVE TREATMENT PROGRAM FOR PREGNANT SUBSTANCE USERS IN A FAMILY MEDICINE CLINIC Ordean A, Kahan M. Publication – PubMed November 2011 www.nofas-uk.org 7 18. UNIVERSAL PREVENTION IS ASSOCIATED WITH LOWER PREVALENCE OF FETAL ALCOHOL SPECTRUM DISORDERS IN NORTHERN CAPE, SOUTH AFRICA: A MULTICENTRE BEFORE-AFTER STUDY Chersich MF, Urban M, Olivier L, Davies LA, Chetty C, Viljoen D. Publication – PubMed 27th October 2011 19. TEACHING NEUROIMAGES: SCHIZENCEPHALY IN FETAL ALCOHOL SYNDROME Spalice A, Del Balzo F, Nicita F, Papetti L, Ursitti F, Salvatori G, Mattiucci C, Mancini F, Tarani L. Publication – PubMed 25th October 2011 20. A REVIEW OF SOCIAL SKILLS DEFICITS IN INDIVIDUALS WITH FETAL ALCOHOL SPECTRUM DISORDERS AND PRENATAL ALCOHOL EXPOSURE: PROFILES, MECHANISMS, AND INTERVENTIONS Kully-Martens K, Denys K, Treit S, Tamana S, Rasmussen C. Publication – PubMed 21st October 2011 21. NEUROPROTECTIVE PEPTIDE ADNF-9 IN FETAL BRAIN OF C57BL/6 MICE EXPOSED PRENATALLY TO ALCOHOL Sari Y, Segu ZM, Youssefagha A, Karty JA, Isailovic D. Publication – PubMed 21st October 2011 22. ANXIETY- AND DEPRESSION-LIKE BEHAVIORS ARE ACCOMPANIED BY AN INCREASE IN OXIDATIVE STRESS IN A RAT MODEL OF FETAL ALCOHOL SPECTRUM DISORDERS: PROTECTIVE EFFECTS OF VOLUNTARY PHYSICAL EXERCISE Patricia S. Brocardo, Fanny Boehme, Anna Patten, Adrian Coxa Joana Gil-Mohapel, Brian R. Christie Publication – ScienceDirect 20th October 2011 23. CHILDREN WITH HEAVY PRENATAL ALCOHOL EXPOSURE EXHIBIT DEFICITS WHEN REGULATING ISOMETRIC FORCE Simmons RW, Nguyen TT, Levy SS, Thomas JD, Mattson SN, Riley EP. Publication – PubMed 20th October 2011 24. BEHAVIORAL DEFICITS AND CELLULAR DAMAGE FOLLOWING DEVELOPMENTAL ETHANOL EXPOSURE IN RATS ARE ATTENUATED BY CP-101,606, AN NMDAR ANTAGONIST WITH UNIQUE NR2B SPECIFICITY B. Lewis, K.A. Wellmann, A.M.H. Kehrberg, M.L. Carter, T. Baldwin, M.
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