DOCSLIB.ORG

Science and Aging Gracefully Part 2: Attempts to Increase Our Health Span and Ward Off the Effects of Age

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Science and Aging Gracefully Part 2: Attempts to Increase Our Health Span and Ward Off the Effects of Age US Sylvia R. Karasu M.D. The Gravity of Weight "A Privileged Way of Knowing:" Science and Aging Gracefully Part 2: Attempts to increase our health span and ward off the effects of age. Posted Feb 05, 2020 Marcus Tullius Cicero, the Roman statesman and perhaps the greatest orator of his era, wrote his classic work de Senectute, On Old Age, when he was about 63 years old. Alas, Cicero never got to experience the glorious benefits of advanced old age that he chronicles: within the year, he was assassinated—beheaded—on the order of his political rivals. Cicero had even successfully defended in court the man, merely attempting to curry favor with those in power, who murders him. (Peck, editor, Harper’s Dictionary of Classical Literature and "The Assassination of Cicero," 15th century, by an Antiquities, pp. 339-345, 1963) And we think our American politicians unknown artist. Cicero, the Roman statesman and orator, was only about 63 years old when he was behave egregiously! killed on the order of his political rivals. He never was able to experience the joys of advanced old age he chronicles in his essay, written within the In de Senectute, though, Cicero makes an heroic effort to persuade year before his death. his audience that elegance and authority come with old age. Most Source: Wikimedia Commons/Public Domain people, though, will find Cicero’s essay unconvincing and prefer to avoid the almost inevitable frailties and deterioration that old age brings. Both the mythological figures of the Cumaean Sibyl, the prophetess of Apollo, and Tithonus, son of a king of Troy, were granted long life by the gods but without remaining young, they bemoaned their fate of a withering and infirm old age and even preferred a death that was no longer available to them. In Part I, I wrote about the declining levels of NAD+—nicotinamide adenine dinucleotide—that occur naturally with age and the possibility of replacing these levels by administering precursors such as nicotinamide riboside (NR). The pharmacokinetics within the human body, though, remain poorly understood, including how these precursors are metabolized in the liver and blood after oral administration. (Yoshino et al, Cell Metabolism, 2018) Further, there is even a report that increasing NAD+ levels could foster the growth of tumors since drugs that deplete NAD+ levels are in development as a "The Young Cicero Reading," painting, circa 1464, cancer treatment. (Yoshino et al, 2018) by Vincenzo Foppa. The Wallace Collection, London. Source: Wikimedia Commons/Public Domain Investigators emphasize that many people take these supplements outside of clinical trials and hence side effects may typically go unreported. “Although the therapeutic potential of boosting NAD+ levels is undeniable, it is time to pause and ponder the potential repercussions" related to the NAD+ replacement. (Katsyuba et al, Nature Metabolism, 2020.) The first clinical trial of NAD+ supplementation in 12 healthy volunteers, administering different dosages on three separate days, occurred only in 2016 and demonstrated that NR did increase blood levels of NAD+. (Trammell et al, Nature Communications, 2016) There have been a few other short-term studies. Depending on the population studied, nicotinamide riboside (NR) did not lead to any serious adverse effects, “but did not result in any striking improvements in any disease to date.” (Katsyuba et al, 2020) There is some suggestion that after 21 https://www.psychologytoday.com/us/blog/the-gravity-weight/202002/privileged-way-knowing-science-and-aging-gracefully 1/4 days of supplementation, there were diminished levels of inflammatory cytokines as well as a trend to decrease blood pressure. Further, researchers caution that there needs to be better methods for accurate measurements of NAD+ levels. (Katsyuba et al, 2020) Substances that have also gained the interest of both scientists and the media are the stilbenes—natural phytochemicals (400 different ones have been identified) that are found in many plants, fruits, and vegetables. (Pan et al, Biofactors, 2018) These are anti-oxidants, i.e., reduce oxidative stress; they are protective against free radicals (Li et al, Biofactors, 2018) and are similar to resveratrol, the substance found in red wine and grapes. Because of their slightly different chemical structure, these stilbenes have better cellular uptake, Self-Portrait, Rembrandt, 1660. Rembrandt was membrane permeability, bioavailability, and a longer half-life than only age 54 when he painted this portrait, one of resveratrol. (Riche et al, Journal of Toxicology, 2013; Pan et al, 2018) 40 self-portraits that survive. He was "unsparing in One of them, pterostilbene, is a potent anti-inflammatory and is the depicting the signs of aging in his own face." (Met Museum description.) natural compound found in blueberries. Source: Metropolitan Museum of Art, NYC/Public Domain. Credit: Bequest of Benjamin Altman, 1913. In recent years, blueberries have been labeled a “superfruit,” but this is a “virtually meaningless term in scientific research,” clarifies James Hamblin, MD (The Atlantic, November 15, 2017). Their popularity has more to do with savvy marketing than any super property. There have even been conferences worthy of the American Civil War, with titles like “The Blue Versus the Gray” in which researchers tout the potential benefits of blueberries for healthy aging. (Ingram, Journals of Gerontology, Series A: Biological Sciences and Medical Sciences, 2019) Studies, though, are difficult to conduct and have been subject to criticism. For example, Allison and colleagues (Vorland et al, Letter to the Editor, PsyArXiv Preprints, 2020), after conducting a thorough statistical analysis, were not able to replicate findings presented in the systematic review by Hein et al (The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 2019) on the effects of blueberries on cognition. Likewise, Brydges and Gaeta, in a Letter to the Editor, found errors in another systematic review on blueberries and concluded, “Based on the current research, researchers should Gustave Caillebotte's "Fruit Displayed on a Stand," avoid drawing definite conclusions regarding the effects of circa 1881. Museum of Fine Arts, Boston. Many blueberries on cognitive performance or mood.” (Brain, Behavior, and studies of blueberries have been criticized. Labeling the blueberry as a "super fruit" reflects Immunity, 2019.) savvy marketing and is a "virtually meaningless term in scientific research." Source: Wikimedia Commons/Public Domain Nevertheless, pterostilbene (PT) itself has been subject to study, particularly to assess its safety. (Riche et al, 2013; Riche et al, Evidence-Based Complementary and Alternative Medicine, 2014) These researchers emphasize that since it is classified as Generally Recognized as Safe (GRAS), it remains exempt from any premarket FDA regulations. They found, in their randomized controlled study of 80 subjects, that PT reduces blood pressure (dose-dependent) but increases levels (unknown significance and cause), of LDL and total cholesterol. (Riche et al, 2014) In another study, nicotinamide riboside (NR) was given with PT. The combination of the two was predicted to work synergistically. This was the first trial of a repeat dose in 120 healthy adults between 60 and 80 with this combination. There was a rise in total cholesterol and LDL but when subjects were stratified by BMI, increased levels were not considered significant and may have also been the result of the “vagaries of randomization” and the fact that LDL levels can vary by as much as 9%. (Dellinger et al Nature Partner Journals: Aging and Mechanisms of Disease, 2017) There are currently four trials sponsored by industry and registered with ClinicalTrials.gov in which researchers are using a combined pill of pterostilbene and nicotinamide riboside to study inflammatory markers; muscle metabolism and exercise; subjective well-being after falls in elderly patients; and changes in liver fat. https://www.psychologytoday.com/us/blog/the-gravity-weight/202002/privileged-way-knowing-science-and-aging-gracefully 2/4 Lee McIntyre writes that what is distinctive about science is not its subject or its method but its attitude toward empirical evidence and a willingness to change its theories on the basis of evidence (The Scientific Attitude: Defending Science from Denial, Fraud, and Pseudoscience, p. 7, 2019). For McIntyre, science is a “privileged way of knowing” (p. 205), and the scientific attitude “is more than an individual mindset; it is a shared ethos that is embraced by a community of scholars who are tasked with judging one another’s theories...” (p. 112) The bottom line: Replenishing naturally declining coenzyme levels or phytochemicals to stave off the mental and physical withering effects of old age makes clinical sense. Preclinical animal studies, William Blake's, Songs of Innocence and of Experience, London," 1794, Fitzwilliam Museum, particularly mouse models, The William Blake Archive. provide strong evidence Source: Wikimedia Commons/Public Domain that metabolic and cardiovascular diseases can be ameliorated or even reversed, and analogously may increase our own human healthspan, i.e., not "The Old Courtesan," by Auguste Rodin, ca. 1885, cast 1910. Rodin captures the withered and necessarily living longer, deteriorated body of old age. but living healthier and Source: Metropolitan Museum of Art, NYC. Public Domain, Credit: Gift of Thomas F. Ryan, 1910. relatively disease-free as we age. The transition from "bench to bedside,"
Load more

Recommended publications
  • Vermeer in the Age of the Digital Reproduction and Virtual
    VERMEER IN THE AGE OF THE DIGITAL REPRODUCTION AND VIRTUAL COMMUNICATION MIRIAM DE PAIVA VIEIRA Universidade Federal de Minas Gerais ABSTRACT: The twentieth century was responsible for the revival of the visual arts, lending techniques to literature, in particular, after the advent of cinema. This visual revival is illustrated by the intersemiotic translations of Girl with a Pearl Earring: a recent low-budget movie was responsible for the revival of ordinary public interest in an art masterpiece from the seventeenth century. However, it was the book about the portrait that catalyzed this process of rejuvenation by verbalizing the portrait and inspiring the cinematographic adaptation, thereby creating the intersemiotic web. In this media-saturated environment we now live in, not only do books inspire movie adaptations, but movies inspire literary works; adaptations of screenplays are published; movies are adapted into musicals, television shows and even videogames. For James Naremore, every form of retelling should be added to the “study of adaptation in the age of the mechanical reproduction and electronic communication” (NAREMORE, 2000: 12-15), long previewed in Walter Benjamin’s milestone article (1936). Nowadays, the celebrated expression could be changed to the age of the digital reproduction and virtual communication, since new technologies and the use of new media have been changing the relations between, and within, the arts. The objective of this essay is to explore Vermeer’s influence on contemporary art and media production, with focus on the collection of portraits from the book entitled Domestic Landscapes (2007) by the Dutch photographer Bert Teunissen, confirming the study of recycling within a general theory of repetition proposed by James Naremore, under the light of intermediality.
    [Show full text]
  • Some Pages from the Book
    AF Whats Mine is Yours.indb 2 16/3/21 18:49 What’s Mine Is Yours Private Collectors and Public Patronage in the United States Essays in Honor of Inge Reist edited by Esmée Quodbach AF Whats Mine is Yours.indb 3 16/3/21 18:49 first published by This publication was organized by the Center for the History of Collecting at The Frick Collection and Center for the History of Collecting Frick Art Reference Library, New York, the Centro Frick Art Reference Library, The Frick Collection de Estudios Europa Hispánica (CEEH), Madrid, and 1 East 70th Street the Center for Spain in America (CSA), New York. New York, NY 10021 José Luis Colomer, Director, CEEH and CSA Centro de Estudios Europa Hispánica Samantha Deutch, Assistant Director, Center for Felipe IV, 12 the History of Collecting 28014 Madrid Esmée Quodbach, Editor of the Volume Margaret Laster, Manuscript Editor Center for Spain in America Isabel Morán García, Production Editor and Coordinator New York Laura Díaz Tajadura, Color Proofing Supervisor John Morris, Copyeditor © 2021 The Frick Collection, Centro de Estudios Europa Hispánica, and Center for Spain in America PeiPe. Diseño y Gestión, Design and Typesetting Major support for this publication was provided by Lucam, Prepress the Centro de Estudios Europa Hispánica (CEEH) Brizzolis, Printing and the Center for Spain in America (CSA). Library of Congress Control Number: 2021903885 ISBN: 978-84-15245-99-5 Front cover image: Charles Willson Peale DL: M-5680-2021 (1741–1827), The Artist in His Museum. 1822. Oil on canvas, 263.5 × 202.9 cm.
    [Show full text]
  • Handbook of the Benjamin Altman
    HAN DBOO K OF THE B ENJ A M I N A LTM AN COLL ECT I ON I OL D WO MAN CUTT I N G H E R NA I LS By Remb randt T H E M E T R O P O L I T A N M U S E U M l‘ O F A R T HANDBOOK OF BENJAMIN ALTM COLLECTION N EW Y O R K N O V E M B E R M C M ' I V Tabl e of Conte nts PA G E LIST OF I LLUSTRATION S I NTRODUCTION HAN D BOO K GALLERY ON E Dutcb P a intings GALLERY Tw o P a intings of Va r i o us ’ Go l dsmitbs Wo rk Enamel s Crysta l s GALLERI ES TH REE AN D FOUR Chinese P o rce l a i ns Snufi Bo ttl es Lacquers GALLERY FIVE Scripture Rugs Tap estr i e s Fu rn iture Misce l l aneo us Objects 891 List of Il l ustrations Ol d Woman Cut t ing her Nail s By Rembrandt The Lady wi t h a Pink By Rembrandt The Man wi t h a Magnifying-Glass By Rembrandt An Ol d Woman i n an Arm-Chai r By Rembrandt Toilet o f Bathsheba after the Bath By R embrandt Young Gi rl Peeling an Apple By Nicol aes M aes The Merry Company By Frans Hal s Yonke r Ramp and his Sweet hea rt By Frans Hal s Philip I V o f Spain By Diego Vel a zque z Luca s van Uff el By A nthony Van Dyck Portrait o f a Man By Giorgione M argaret Wyatt , Lady Lee By Hans Hol be in the Yo unger v iii L I S T O F I L L U S T R A T I O N S Th e Holy Family By A ndrea M a ntegna The Last Communion of Saint J e rome By Bo tt icel l i ’ Borso d Est e By Cosimo Tura Portrait of a Man By Dirk Bou ts The Betrothal o f Sai nt Catheri ne By Hans M e ml i ng Portrait o f an Ol d Man By Hans Meml ing Triptych M l anese l ate teenth centur i , fif y o f d Cup gol and enamel , called the Ros pigl io si Coupe By Benvenuto Cel l ini Triptych o f Limoges Enamel By Na rdon P enicaud Candlesticks o f Rock Crystal and Silver Gilt German sixtee nth ce ntur , y Ta zz a o f Rock Crystal and E nameled Gold Ital ian s xtee nth centur , i y Portable Holy Water Stoup Ital an s xtee nth ce ntur i , i y Ewer of Smoke Color Rock Crystal German s xtee nth centur , i y Rose Water Vase o f Rock Crystal Ital an s xteenth ce ntur i , i y L I S T O F I L L U S T R A T I O N S ix FAC ING PAG E — Cylindrical Vase of Garniture No s .
    [Show full text]
  • Dutch Paintings in the Metropolitan Museum of Art
    Hidden Gems and Fallen Stars: Dutch Paintings in The Metropolitan Museum of Art Esmée Quodbach Center for the History of Collecting The Frick Collection and Art Reference Library, New York Enschede, March 2011 Opening reception in the picture gallery at The Metropolitan Museum of Art, 681 Fifth Avenue, New York. February 20, 1872 Dutch pictures part of the “Purchase of 1871” Jan van Goyen Salomon van Ruysdael Jan Davidsz. de Heem Jacob Vosmaer Acquired as by Frans Hals now Style of Frans Hals, Dutch, Nicolaes Berchem second quarter of the 17th Johannes Lingelbach century Govert Flinck Civic Guardsmen from the Company of Captain Joan Huydekoper and Lieutenant Frans van Waveren, 1648 Purchase of 1871 Sold Amsterdam Museum (Amsterdams Historisch Museum) Attributed to Rembrandt Style of Rembrandt (17th century or later) John Singer Sargent Portrait of a Man, possibly 1650s Man with a Beard Henry Gurdon Marquand (1819-1902), 1897 Princeton University Art Museum Acquired by Marquand Acquired by Marquand in 1889 in 1883 for $25,000 Accepted as a Rembrandt until the 1940s Attributions as per Liedtke 2007 Johannes Vermeer Young Woman with a Water Pitcher, c. 1662 Acquired by Marquand in 1887 Johannes Vermeer Collis Huntington (1821-1900) Woman with a Lute, c. 1662-63 Acquired before 1897 reportedly for 2,000 francs (about $400) Dutch Marquand Paintings Gabriel Metsu Frans Hals The Marquand Gallery of Old Masters at The Metropolitan Museum of Art, 1897. Print. Frans Hals Reworked, probably 18th century Edgar Degas Louisine and H.O. Havemeyer Sulking, c. 1870 Bought in 1896 for $4,500 Havemeyer Rembrandts (attributions as per Liedtke 2007) Style of Rembrandt (Dutch, 1640s) Rembrandt Portrait of a Man and Portrait of a Woman Portrait of a Man and Portrait of a Woman (so-called Van Beresteyn Portraits), 1632 Style of Jacob Backer (Dutch, second quarter 17th century) Portrait of an Old Woman Rembrandt Herman Doomer, 1640 Bought by H.O.
    [Show full text]
  • Fashioning Desire at B. Altman & Co.: Ethics and Consumer Culture In
    City University of New York (CUNY) CUNY Academic Works All Dissertations, Theses, and Capstone Projects Dissertations, Theses, and Capstone Projects 6-2016 Fashioning Desire at B. Altman & Co.: Ethics and Consumer Culture in Early Department Stores Tessa Maffucci Graduate Center, City University of New York How does access to this work benefit ou?y Let us know! More information about this work at: https://academicworks.cuny.edu/gc_etds/1338 Discover additional works at: https://academicworks.cuny.edu This work is made publicly available by the City University of New York (CUNY). Contact: [email protected] FASHIONING DESIRE AT B. ALTMAN & CO.: ETHICS AND CONSUMER CULTURE IN EARLY DEPARTMENT STORES by TESSA MAFFUCCI A master’s thesis submitted to the Graduate Faculty in Liberal Studies in partial fulfillment of the requirements for the degree of Master of Arts, The City University of New York 2016 © 2016 TESSA MAFFUCCI All Rights Reserved ii Fashioning Desire at B. Altman & Co.: Ethics and Consumer Culture in Early Department Stores by Tessa Maffucci This manuscript has been read and accepted for the Graduate Faculty in Liberal Studies in satisfaction of the thesis requirement for the degree of Master of Arts. _________________ _______________________________________ Date Eugenia Paulicelli Thesis Advisor _________________ _______________________________________ Date Matthew Gold Executive Officer THE CITY UNIVERSITY OF NEW YORK iii ABSTRACT Fashioning Desire at B. Altman & Co.: Ethics and Consumer Culture in Early Department Stores by Tessa Maffucci Advisor: Eugenia Paulicelli We live in an age of fast fashion. Clothing is produced in greater volumes than ever before and the lifecycle of each garment keeps getting shorter and shorter.
    [Show full text]
  • Botticelli Past and Present Ever, the Significant and Continued Debate About the Artist
    The recent exhibitions dedicated to Botticelli around the world show, more than and Present Botticelli Past ever, the significant and continued debate about the artist. Botticelli Past and Present engages with this debate. The book comprises four thematic parts, spanning four centuries of Botticelli’s artistic fame and reception from the fifteenth century. Each part comprises a number of essays and includes a short introduction which positions them within the wider scholarly literature on Botticelli. The parts are organised chronologically beginning with discussion of the artist and his working practice in his own time, moving onto the progressive rediscovery of his work from the late eighteenth to the turn of the twentieth century, through to his enduring impact on contemporary art and design. Expertly written by researchers and eminent art historians and richly illustrated throughout, the broad range of essays in this book make a valuable contribution to Botticelli studies. Ana Debenedetti is an art historian specialising in Florentine art, artistic literature and workshop practice in the Renaissance. She is Curator of Paintings at the Victoria and Albert Museum, responsible for the collections of paintings, drawings, watercolours and miniatures. She has written and published on Renaissance art and Botticelli philosophy. Caroline Elam is a Senior Research Fellow at the Warburg Institute, University of London. She specialises in architecture, art and patronage in the Italian Renaissance and in the reception of early Italian art in the late nineteenth and twentieth century. Past She has held academic positions at the University of Glasgow, King’s College, Cambridge and Westfield College, University of London.
    [Show full text]
  • Altman Foundation Grants List
    Altman Foundation Grants List by year first funded (as of july 2013) legend * Organization was an Altman grantee at some point prior to the 1985 sale of B. Altman & Co. and has also been a grantee in the years since that transition for the Foundation. ° Organization has received Altman grant(s) totaling $1 million or more. 1914 Stadium University Fund Equity Players, Inc. Hebrew Orphan Asylum United Bldg. Fund Campaign of Federated Jewish French and Polyclinic Medical School and Health Hebrew Technical School for Girls Institutions Center Home for Aged and Infirm Hebrews United Jewish Appeal-Federation of Jewish Girls Service League of America Lebanon Hospital /Bronx-Lebanon Hospital Philanthropies of New York, Inc.*° Goldman Concerts Band Center* The Young Women’s Christian Association of the Hartman-Homecrest Library Bureau City of New York* Jewish Education Assn. Montefiore Home/Montefiore Medical Center*° Josephine Home, Inc. St. Mark’s Hospital 1920 Maternity Center Association Cardinal’s Committee of the Laity/Archdiocese of The Metropolitan Museum of Art*° 1917 New York*° The National Stage Woman’s Exchange Allies Bazaar Catholic Charities Archdiocese of New York*° Neighborhood Circle American Red Cross in Greater New York* Flower Hospital New York American Christmas Relief Fund, Inc. Community Service Society of New York* Girl Scout Council of Greater New York, Inc.* The New York Friends of Boys Greater New York Council, Boy Scouts of America Joint Distribution Committee Greater New York New York Guild for Jewish Blind Jewish War Relief Committee—New York Fund New York Heart Association Special Benevolent Society National Urban League, Inc.* The New York Society for the Prevention of Cruelty St.
    [Show full text]
  • Frans Hals in America: Another Embarrassment of Riches
    Volume 9, Issue 1 (Winter 2017) Frans Hals in America: Another Embarrassment of Riches Dennis P. Weller [email protected] Recommended Citation: Dennis P. Weller, “Frans Hals in America: Another Embarrassment of Riches,” JHNA 9:1 (Winter 2017), DOI: 10.5092/jhna.2017.9.1.5 Available at https://jhna.org/articles/frans-hals-america-another-embarrassment-riches/ Published by Historians of Netherlandish Art: https://hnanews.org/ Republication Guidelines: https://jhna.org/republication-guidelines/ Notes: This PDF is provided for reference purposes only and may not contain all the functionality or features of the original, online publication. This PDF provides paragraph numbers as well as page numbers for citation purposes. ISSN: 1949-9833 JHNA 7:2 (Summer 2015) 1 FRANS HALS IN AMERICA: ANOTHER EMBARRASSMENT OF RICHES Dennis P. Weller The story of Frans Hals in America has been nearly a century and a half in the making. The legendary museum director W. R. Valentiner was the first to address the topic, as is seen in his 1936 survey volume Frans Hals in America. Unfor- tunately, the pages of his book are filled with scores of misattributions. In addition to discussing early collecting and scholarship on Hals, I will update the story begun by Valentiner and continued by Seymour Slive and others from the second half of the twentieth century to the present. Today, the flow of Hals’s paintings coming to America has slowed to a trickle, but notable acquisitions continue to reach our shores. The content of this essay certainly dovetails with a number of Walter Liedtke’s scholarly interests.
    [Show full text]
  • 2005 Annual Report
    ANNUAL REPORT 2005 ANNUAL REPORT 2005 History of the he mission of the Altman Foundation reflects much of the personality and vision of Tits founder, Benjamin Altman. Altman was a unique and generous individual whose dry goods store, B. Altman & Co., founded in 1865 on Third Avenue and 10th Street, became a major department store. Altman moved his store from 10th Street to 19th Street and Sixth Avenue and finally, in 1906, to the landmark building at 34th Street and Fifth Avenue. Altman’s reflected the commitment of its founder to service to its cus- tomers and generosity to its employees. Until its closing in 1989, Altman’s was beloved by generations of New Yorkers. The Altman Foundation was established in 1913 under Benjamin Altman’s will “for the benefit of such charitable and educational institutions in the City of New York as said directors shall approve”. His will bequeathed all his capital stock in B. Altman & Co. to the Altman Foundation. Outright bequests in Altman’s will presaged the areas that would become major concerns of the Foundation. He made bequests to several hospitals, the Educational Alliance and the National Academy of Design. He gave his art collection to the Metropolitan Museum of Art. His dedication to the welfare of the people of New York City and his interests in health, education and the arts are his legacy. Following Altman’s death, Colonel Michael Friedsam, his close relative and colleague, led the business and the Foundation until his own death in 1931. Friedsam was also an art collector and a philanthropist with a deep interest in New York.
    [Show full text]
  • Catalogue of Paintings
    pi lliliiill, COLLEGE OF ARCHITECTURE LIBRARY Cornell University Library N 610.A65 1920 Catalogue of paintings / 3 1924 020 595 173 Cornell University Library The original of tliis book is in tine Cornell University Library. There are no known copyright restrictions in the United States on the use of the text. http://www.archive.org/details/cu31924020595173 THE METROPOLITAN MUSEUM OF ART CATALOGUE OF PAINTINGS MCMXX CATALOGUE OF PAINTINGS VIRGIN ENTHRONED WITH SAINTS BY RAPHAEL THE METROPOLITAM MUSEUM OF ART CATALOGUE OF PAINTINGS BY BRYSON BURROUGHS CURATOR , DEPARTMENT OF PAINTINGS FIFTH EDITION NEW YORK M C M X X hr 33^t| FIRST EDITION, COPYRIGHT, FEBRUARY, I9I4 SECOND EDITION, COPYRIGHT, FEBRUARY, I916 THIRD EDITION, COPYRIGHT, JUNE, I917 FOURTH EDITION, COPYRIGHT, MARCH, I919 FIFTH EDITION, COPYRIGHT, JUNE, I92O BY THE METROPOLITAN MUSEUM OF ART PREFACE alphabetical arrangement by the names of artists, or by AN schools where the artists are unknown, is followed in this . book. In the attempt to solve the problem of number- ^ ing a rapidly growing collection of paintings, the experi- ment has been made here of adapting the C. A. Cutter system, long in use in libraries. To use the catalogue it is not necessary to be familiar with the system of numbering, but for those who may be interested an explanation follows. It consists of a combination of letters and numbers, composed of the initial letter of the author's name followed by numbers that represent the succeeding letters of the same, so that additional entries can be inserted without disturbing the sequence of the letters or the numerals.
    [Show full text]
  • Vermeer's Masterpiece “The Milkmaid”
    The Metropolitan Museum of Art Vermeer’s Masterpiece “The Milkmaid” September 10, 2009–November 29, 2009 On the occasion of the 400th anniversary of Henry Hudson’s historic voyage to Manhattan from Amsterdam, that city’s Rijksmuseum will send The Milkmaid, perhaps the most admired painting by Johannes Vermeer (1632–1675), to the Metropolitan Museum. To celebrate this extraordinary loan, the Metropolitan Museum will present Vermeer’s Masterpiece The Milkmaid, a special exhibition that will bring together all five paintings by Vermeer from its collection, along with a select group of works by other Dutch artists, placing Vermeer’s superb picture in its historical context. Along with The Milkmaid, important works by Pieter de Hooch, Gabriël Metsu, Nicolaes Maes, Emanuel de Witte, and Gerard ter Borch will be on view. All were masters who, like Vermeer, were active during the remarkable period of exploration, trade, and artistic flowering that occurred during the Dutch Golden Age in the seventeenth century. Vermeer’s Masterpiece The Milkmaid will mark the first time that the painting has traveled to the United States since it was exhibited at the 1939 World’s Fair. Accompanied by a publication. The exhibition is made possible by the William Randolph Hearst Foundation, Daphne Recanati Kaplan and Thomas S. Kaplan, and Bernard and Louise Palitz. MMA/Vermeer’s Masterpiece: The Milkmaid/Antenna Audio Guide DLT Stop 1 List/ Antenna Audio Inc. and the Metropolitan Museum of Art ©2009 Audio Tour: Stop List Stop 600: Introduction Stop 601 Stop 601a Stop 602 Stop 602a The Milkmaid, ca. 1657–58 Johannes Vermeer (Dutch, 1632–1675) Oil on canvas; 18 x 16 1/8 in.
    [Show full text]
  • Dutch Paintings
    THE METRO ART DUTCH PAINTINGS A PICTURE BOOK THE METROPOLITAN MUSEUM OF ART UTGH W^AINTINGS A PICTURE BOOK NEW YORK, N. Y. 1944 COPYRIGHT BY THE METROPOLITAN MUSEUM OF ART MAY, HJM in (On corci) Frans Hals (horn after 1580 - died 1666) Malic Babbe Purchase, 1871 C* [ DUTCH PAINTINGS UTCH art of the seventeenth century come an outcast. The burghers of the new is the achievement of a people that democracy welcomed her to their homes. Every asserted its Protestantism with mili­ Dutch home was a little museum, and there tant fervor. Yet it is not a protest were capitalists in the Republic who owned but an affirmation. Hatred of Spanish tyranny veritable art galleries. John Evelyn, the diarist, and Roman intolerance found no expression found to his surprise paintings by good mas­ in the works of the painters. Their art did not ters offered for sale at the annual fair held in care for negation. They did not proclaim on the open at Rotterdam. He was told that the canvas what manifestations of life they did not large output of pictures and their cheapness like, they spoke in color and line of those they were due to the lack of land available for in­ admired. They affirmed the worthwhileness of vestment, "so that it is an ordinary thing to existence, their love of beauty, their joy in the find a common farmer lay out two or three picturesque charm of town ancf country, the thousand pounds in this commodity." The people's pride in the well-ordered neatness of Frenchman Sorbiere knew a Dutch book- their homes.
    [Show full text]