At the Forefront of Virus – Host Interactions Viruses 2016 Book Viruses – Program and Abstract
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At the Forefront of Virus – Host Interactions Viruses 2016 – Program and Abstract and – Program Viruses Book 2016 26 – 28 January 2016 Pharmacenter, University of Basel Basel, Switzerland Program and Abstract Book WLAN: unibas-event Login: eventbzpz Password: Virus-2016! Twitter Handle: @VirusesMDPI Twitter Hashtag: #Viruses2016 Organizing Committees and Conference Secretariat Executive Committee Chairman Members Dr. Eric O. Freed Dr. Paul Ahlquist Co-Chairman Dr. Jens H. Kuhn Dr. Thomas Klimkait Dr. Peter D. Nagy Dr. Charles M. Rice Dr. Eric M. Poeschla Dr. Ry Young Conference Secretariat Dr. Franck Vazquez Dr. Delphine Guérin Ms. Delia Mihaila Ms. Cornelia Bauer Mr. Matthias Burkhalter Dr. Shu-Kun Lin i Welcome by Dr. Eric O. Freed Dear authors and attendees, The last few years have witnessed enormous progress in virology research, with major breakthroughs taking place across a wide range of virology-related disciplines. At the same time, the global impact of viral infections on human health has never been clearer. The conference Viruses 2016 - At the Forefront of Virus–Host Interactions will bring together leading virologists from around the world to share recent developments in their research. The sessions are organized in a theme-based manner, with related topics discussed from the perspective of diverse viruses, ranging from bacteriophage, plant, and insect viruses to animal viruses. The Viruses 2016 - At the Forefront of Virus–Host Interactions will be held in Basel, Switzerland, from 26th to 28th of January 2016. It will comprise five plenary sessions to highlight the most exciting developments and the latest breakthroughs in virology. Dr. Eric O. Freed Conference Chair ii Welcome by Prof. Dr. Thomas Klimkait Dear colleagues planning to attend the Viruses 2016 conference “At the Forefront of Virus–Host Interactions”! I am most honored to be able to invite you to the lovely city of Basel on the Rhine, the place where three countries meet at one point as seen in this photo. The picture of our “Three-Country-Corner” may serve as a symbol for the beauty of international collaboration in science, and I trust that this conference will be the place where a lively exchange of thoughts, vivid discussion of scientific work, and a multitude of interactions in an open spirit will yield valuable new contacts and ideas. We have chosen the title “At the Forefront of Virus–Host Interactions” as this conference will especially focus on key viral principles. We truly hope that this basic science perspective will manage to complement the multitude of other events that focus on clinical and preclinical work, and that it will cross-fertilize to all disciplines from basic research to clinical application! A number of well-known experts in their respective fields are attending with excellent speakers, and outstanding research abstracts! I am very much looking forward to a very productive conference with excellent presentations and discussions! Dr. Thomas Klimkait Co-Chair iii Welcome by Prof. Dr. Dr. h.c. Andrea Schenker-Wicki and Prof. Dr. Edwin Constable It is our pleasure and honor to welcome Viruses 2016 to the Biozentrum of the University of Basel. Our University prides itself on its reputation and achievements in life sciences and translational sciences and we are particularly pleased that this conference, in an area of fundamental importance to human health, is taking place in Basel. Since the Ebola outbreak in 2015, viruses have rarely been far from the news. These tragic epidemics emphasize the need for more information on the fundamentals of the molecular biology and genetics of viruses, as well as a better understanding of the viruses’ interactions with host organisms and molecular treatments. In the context of public health impact, the theme of "antiviral innate immunity" is of immense interest and importance, as are the sessions on interactions of viruses with membranes and replication organelles. In the 124 years since the first description of the Tobacco Mosaic Virus in 1892, enormous strides in our understanding of viruses at all levels have been made. Nevertheless, conferences like this serve to emphasize that research in this area is at the cutting edge and of profound relevance to mankind. We wish all participants a stimulating and enjoyable conference and hope that, in addition to fruitful scientific sessions and exchanges with colleagues, you will also find a little time to enjoy our campus and the city. Prof. Dr. Dr. h.c. Andrea Schenker-Wicki President University of Basel Prof. Dr. Edwin Constable Vice President for Research University of Basel iv Acknowledgments Platinum Sponsor Sponsors Exhibitors Patronage v Conference Sponsoring Journal www.mdpi.com/journal/viruses Session Sponsoring Journals www.mdpi.com/journal/ncrna www.mdpi.com/journal/pathogens www.mdpi.com/journal/biology www.mdpi.com/journal/genes www.mdpi.com/journal/vaccines vi Table of Contents 1 General Information ................................................................. 1 1.1 Conference Topics .................................................................................................... 3 1.2 Conference Venue .................................................................................................... 3 1.3 Registration Desk ...................................................................................................... 3 1.4 Wireless Internet Access ........................................................................................... 3 1.5 Directions and Map ................................................................................................... 4 1.6 Switzerland and the Tri-National-Region ................................................................... 4 1.7 Basel ......................................................................................................................... 4 1.8 Best Connections ...................................................................................................... 5 1.9 Dynamic Economy .................................................................................................... 5 1.10 Fair Weather City ...................................................................................................... 5 1.11 The University of Basel .............................................................................................. 5 1.12 Biocenter/PharmaCenter .......................................................................................... 6 1.13 Location .................................................................................................................... 7 1.14 How to Reach the Venue........................................................................................... 8 1.15 Inside the Biocenter/PharmaCenter .......................................................................... 9 1.16 Conference Dinner .................................................................................................. 10 1.17 Visiting Basel and Dining Out .................................................................................. 11 1.18 Emergency Information .......................................................................................... 15 2 Conference Program ............................................................... 17 2.1 Program at a Glance................................................................................................ 18 2.2 Detailed Program .................................................................................................... 19 3 Oral Presentation Abstracts .................................................... 23 3.1 Session 1: General Topics in Virology ...................................................................... 25 3.2 Session 2: Antiviral Innate Immunity ....................................................................... 35 3.3 Session 3: Non-Coding RNAs ................................................................................... 47 3.4 Session 4: Interactions between Viruses and Membranes ....................................... 57 3.5 Session 5: Replication Organelles ............................................................................ 69 4 Poster Presentation Abstracts ................................................ 77 5 List of Participants ................................................................ 199 vii viii 1 General Information IMPACT FACTOR viruses 3.353 $Q2SHQ$FFHV-RXUQDO Viruses ( ISSN 1999-4915 ) 6SHFLDO,VVXHV2SHQIRU6XEPLVVLRQV± *:$6DQG%H\RQG2PLFV5HVHDUFKIRU,QVLJKWV 7 Replicating-Competent LQWR+XPDQ9LUXV,QWHUDFWLRQVDQG3DWKRJHQHVLV Reporter-Expressing Viruses Guest Editor: Dr. Cheryl Winkler Guest Editor: Dr. Luis Martinez-Sobrido Deadline: 30 September 2016 Deadline: 31 January 2016 2 Lectins as Antiviral 8 RNA Packaging Guest Editor: Dr. Barry O'Keefe Guest Editors: Dr. Roland Marquet and Prof. Polly Roy Deadline: 31 July 2016 Deadline: 31 May 2016 3 Molecular Plant Virus—Insect 9 Use of Novel Cell Culture Models Vector Interactions to Understand Viral-Host Interactions Guest Editor: Assoc. Prof. Ralf Dietzgen Guest Editor: Prof. Charu Kaushic Deadline: 30 June 2016 Deadline: 30 June 2016 4 Recent Progress in Bunyavirus Research 10 Viral Subversion of Stress Responses Guest Editors: Dr. Jane Tao and Dr. Pierre-Yves Lozach and Translational Control Deadline: 27 February 2016 Guest Editor: Dr. Craig McCormick Deadline: 29 February 2016 5 Recent Progress in Dengue Virus Research 2016 Guest Editors: Dr. Ali Amara and Prof.