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European Chemistry Congress June 16-18, 2016 Rome, Italy conferenceseries.com conferenceseries.com 513th Conference European Chemistry Congress June 16-18, 2016 Rome, Italy Posters Page 98 Adriana A Lopes et al., Chem Sci J 2016, 7:2(Suppl) http://dx.doi.org/10.4172/2150-3494.C1.003 conferenceseries.com European Chemistry Congress June 16-18, 2016 Rome, Italy Unnatural fluoro-oxindole alkaloids produced by Uncaria guianensis plantlets Adriana A Lopes, Bruno Musquiari, Suzelei de C França and Ana Maria S Pereira Universidade de Ribeirão Preto, Brazil atural products and their analogues have been sources of numerous important therapeutic agents. The medicinal plant NU. guianensis (Rubiaceae) cultured in vitro produce four oxindole alkaloids that displays anti-tumoral activity. Natural products can be modified by several approaches, one of which is precursor-directed biosynthesis (PDB). Thus, the aim of this work was apply precursor-directed biosynthesis approach to obtain oxindole alkaloids analogues using in vitro Uncaria guianensis. Plantletes were cultivated into culture medium supplemented with 1mM of 6-fluoro-tryptamine, the indol precursor of alkaloids biosynthesis. U. guianensis explants were maintained at 25±2°C, 55-60% relative humidity under the same photoperiod and light intensity. After 30 days, a methanolic extract from U. guianensis was obtained and analysed by HPLC- DAD analytical procedure. The chromatogram showed four natural alkaloids (mitraphylline, isomitraphylline, rhynchophylline and isorhynchophylline and four additional peaks. Semi-preparative HPLC allowed isolation and purification of these four oxindole alkaloids analogues and the identity of the peaks was confirmed from high-resolution MS data (HRESIMS/MS in positive mode). All data confirmed that Uncaria guianensis produced fluoro-oxindole alkaloids analogues. Biography Adriana A Lopes is from Universidade de Ribeirão Preto, Brazil. [email protected] Notes: Chem Sci J 2016 Volume 7, Issue 2(Suppl) ISSN: 2150-3494, CSJ an open access journal Euro Chemistry 2016 June 16-18, 2016 Page 99 Melitta Patrícia Kiss et al., Chem Sci J 2016, 7:2(Suppl) http://dx.doi.org/10.4172/2150-3494.C1.003 conferenceseries.com European Chemistry Congress June 16-18, 2016 Rome, Italy Spectrophotometric investigation of early lanthanide(III) porphyrin complexes Melitta Patrícia Kiss, Muhammad Imran, Zsolt Valicsek and Ottó Horváth University of Pannonia, Hungary arger-sized metal ions are not able to coplanarly fit into the cavity of the porphyrin ring; they are located out of the ligand Lplane, resulting in out-of-plane (OOP or sitting-atop=SAT) complexes OOP position promotes the formation of bis- or oligoporphyrins, so-called sandwich complexes. Lanthanide(III) ions offer good opportunities to fine tune the out-of-plane distances, utilizing the well-known lanthanide contraction. The UV-Vis absorption bands of SAT complexes represent redshift compared to the free-base ligand. SAT complexes can be used as photocatalysts in redox reactions, as photosensors in the medical science in luminescence imaging and as polymer diodes in cancer treatment. We investigated the reaction between the 5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrin and early lanthanide(III) ions (La-Gd), as well as the effect of the ionic strenght, the temperature and the potential axial ligands on these processes. The structures of different complexes were identified on the basis of their UV-Vis absorption spectra. The bidentate O-donor acetate and glycol, as well as the monodentate ethanol and chloride can enhance the coordination of the first porphyrin ligand, due to their axial effect, but they can hinder the connection of an additional porphyrin. In the presence of non-coordinating perchlorate anion, bisporphyrins can form, too. At lower temperatures, the lanthanide(III) ions were not able to coordinate into the cavity of the macrocycle, to the softer pyrrolic nitrogens, rather to the sulfonato groups, to the harder oxygens; resulting in the formation of the free-base ligands’ tail-to-tail dimer. So the coordination position of metal ion can be influenced by temperature. Biography Melitta Patrícia Kiss got her MSc degree in Chemistry at University of Pannonia, Veszprém, Hungary. Now, she is a PhD student at the Department of General and Inorganic Chemistry at the same university. In her research work, she studies the formation of lanthanide porphyrin complexes from equilibrial and kinetic aspects since 6 years. [email protected] Notes: Chem Sci J 2016 Volume 7, Issue 2(Suppl) ISSN: 2150-3494, CSJ an open access journal Euro Chemistry 2016 June 16-18, 2016 Page 100 Orsolya Fónagy et al., Chem Sci J 2016, 7:2(Suppl) http://dx.doi.org/10.4172/2150-3494.C1.003 conferenceseries.com European Chemistry Congress June 16-18, 2016 Rome, Italy Photoinduced heterogenous catalysis with TiO2 and kaolinite Orsolya Fónagy1, Balázs Zsirka2, Erzsébet Szabó-Bárdos1, Erzsébet Horváth2 and Ottó Horváth1 1University of Pannonia, Hungary 2Institute of Environmental Engineering, Hungary eterogeneous photocatalysis is a worldwide researched Advanced Oxidation Process. It can be successfully applied for Hdegradation of various organic pollutants into harmless or less harmful compounds. The efficiency of this technology can be increased in multiple ways, thus it has the flexibility for being used in practical application. The efficiency can be significantly enhanced by the combination with other oxidative procedures such as ozonation and by using new kind of catalysts or modifing their surface with precious metals. The latter helps the charge separation therefore slows down the recombination of holes and electrons. Furthermore with the “coloring” of the semiconductor there is a possibilty to extend the light absorption range of the catalyst to the visible light wave lengths. Our research group studied TiO2 and kaolinite based heterogenous photocatalysis by the degradation of different model compounds. In this work, we summarize our results regarding the mineralization of benzenesulfonic acid and oxalic acid on the previous two catalysts. Biography Orsolya Fónagy has started her PhD in 2014 at University of Pannonia. Her PhD topic is “Investigation and development of water treatment procedures based on heterogeneous photocatalysis”. She is a co-author in two publications at scientific journals. [email protected] Notes: Chem Sci J 2016 Volume 7, Issue 2(Suppl) ISSN: 2150-3494, CSJ an open access journal Euro Chemistry 2016 June 16-18, 2016 Page 101 Hegedűs Péter et al., Chem Sci J 2016, 7:2(Suppl) http://dx.doi.org/10.4172/2150-3494.C1.003 conferenceseries.com European Chemistry Congress June 16-18, 2016 Rome, Italy Photocatalytic decomposition of a nonionic detergent Hegedűs Péter, Erzsébet Szabó-Bárdos, Krisztián Horváth and Ottó Horváth University of Pannonia, Hungary he newer chemicals that appears nowdays can’t always be treated with the current sewage treatment methods. Keeping the Tenvironmental aspects in mind, new procedures should be developed. Triton X-100 is one of the most widely applied man- made nonionic surfactants. This detergent is utilized as both household and industrial cleaning agent. Triton X-100 can hardly be degraded by biological treatment under anaerobic conditions, and even in aerobic systems it can be just partly mineralized. Thus, it can reach natural waters, damaging various living organisms there. Hence, application of a more efficient degradation method is indispensable for the total mineralization of this surfactant. A possible solution of this problem is the application of heterogeneous photocatalysis. It is an advanced oxidation process that uses UV irradiaton to form highly reactive radicals on the surface of a semiconductor catalyst. We have thoroughly examined the photocatalytic degradation of Triton X-100 under various circumstances. The process was monitored by following the spectral changes, the organic carbon content, and the actual concentration (UHPLC method). It has been established that Triton X-100 could be mineralized by TiO2 mediated heterogeneous photocatalysis However, one obstacle to the in field use is that if the catalyst is used in slurry form, the catalyst separation from the liquid phase is difficult and makes the technology more expensive. This problem can be eliminated if the catalyst is immobilized. We managed to create a foil catalyst from poli(vinyl-alcohol) and Degussa P25 TiO2 which is capable of breaking down the modell compound. Biography Péter Hegedűs has completed his M.Sc. in Environmental Engineering at the age of 25 years from University of Pannonia. He is a first year PhD student at University of Pannonia Department of General and Inorganic Chemistry. His subject is: The preparation and characterisation of immobilised photocatalyst, and application for the degradation of pollutants. [email protected] Notes: Chem Sci J 2016 Volume 7, Issue 2(Suppl) ISSN: 2150-3494, CSJ an open access journal Euro Chemistry 2016 June 16-18, 2016 Page 102 Marius Zaharia , Chem Sci J 2016, 7:2(Suppl) http://dx.doi.org/10.4172/2150-3494.C1.003 conferenceseries.com European Chemistry Congress June 16-18, 2016 Rome, Italy Patented method-based evaluation of the toxicity of some uncoupling dinitrophenol-like compounds Marius Zaharia Alexandru Ioan Cuza University, Romania lthough the dinitrophenols and related compounds are deeply poisonous, they are still used as pesticides, drugs or Aeven weight loss agents. Today, DNP is used by bodybuilders, often illegally, to rapidly lose body fat before contests. Numerous
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