(WASF1) (NM 003931) Human Untagged Clone Product Data
Total Page:16
File Type:pdf, Size:1020Kb
OriGene Technologies, Inc. 9620 Medical Center Drive, Ste 200 Rockville, MD 20850, US Phone: +1-888-267-4436 [email protected] EU: [email protected] CN: [email protected] Product datasheet for SC117699 WAVE 1 (WASF1) (NM_003931) Human Untagged Clone Product data: Product Type: Expression Plasmids Product Name: WAVE 1 (WASF1) (NM_003931) Human Untagged Clone Tag: Tag Free Symbol: WASF1 Synonyms: NEDALVS; SCAR1; WAVE; WAVE1 Vector: pCMV6-XL5 E. coli Selection: Ampicillin (100 ug/mL) Cell Selection: None This product is to be used for laboratory only. Not for diagnostic or therapeutic use. View online » ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 1 / 3 WAVE 1 (WASF1) (NM_003931) Human Untagged Clone – SC117699 Fully Sequenced ORF: >OriGene ORF within SC117699 sequence for NM_003931 edited (data generated by NextGen Sequencing) ATGCCGCTAGTGAAAAGAAACATCGATCCTAGGCACTTGTGCCACACAGCACTGCCTAGA GGCATTAAGAATGAACTGGAATGTGTAACCAATATTTCCTTGGCAAATATAATTAGACAA CTAAGTAGCCTAAGTAAATATGCTGAAGATATATTTGGAGAATTATTCAATGAAGCACAT AGTTTTTCCTTCAGAGTCAACTCATTGCAAGAACGTGTGGACCGTTTATCTGTTAGTGTT ACACAGCTTGATCCAAAGGAAGAAGAATTGTCTTTGCAAGATATAACAATGAGGAAAGCT TTCCGAAGTTCTACAATTCAAGACCAGCAGCTTTTCGATCGCAAGACTTTGCCTATTCCA TTACAGGAGACGTACGATGTTTGTGAACAGCCTCCACCTCTCAATATACTCACTCCTTAT AGAGATGATGGTAAAGAAGGTCTGAAGTTTTATACCAATCCTTCGTATTTCTTTGATCTA TGGAAAGAAAAAATGTTGCAAGATACAGAGGATAAGAGGAAGGAAAAGAGGAAGCAGAAG CAGAAAAATCTAGATCGTCCTCATGAACCAGAAAAAGTGCCAAGAGCACCTCATGACAGG CGGCGAGAATGGCAGAAGCTGGCCCAAGGTCCAGAGCTGGCTGAAGATGATGCTAATCTC TTACATAAGCATATTGAAGTTGCTAATGGCCCAGCCTCTCATTTTGAAACAAGACCTCAG ACATACGTGGATCATATGGATGGATCTTACTCACTTTCTGCCTTGCCATTTAGTCAGATG AGTGAGCTTCTGACTAGAGCTGAGGAAAGGGTATTAGTCAGACCACATGAACCACCTCCA CCTCCACCAATGCATGGAGCAGGAGATGCAAAACCGATACCCACCTGTATCAGTTCTGCT ACAGGTTTGATAGAAAATCGCCCTCAGTCACCAGCTACAGGCAGAACACCTGTGTTTGTG AGCCCCACTCCCCCACCTCCTCCACCACCTCTTCCATCTGCCTTGTCAACTTCCTCATTA AGAGCTTCAATGACTTCAACTCCTCCCCCTCCAGTACCTCCCCCACCTCCACCTCCAGCC ACTGCTTTGCAAGCTCCAGCAGTACCACCACCTCCAGCTCCTCTTCAGATTGCCCCTGGA GTTCTTCACCCAGCTCCTCCTCCAATTGCACCTCCTCTAGTACAGCCCTCTCCACCAGTA GCTAGAGCTGCCCCAGTATGTGAGACTGTACCAGTTCATCCACTCCCACAAGGTGAAGTT CAGGGGCTGCCTCCACCCCCACCACCGCCTCCTCTGCCTCCACCTGGCATTCGACCATCA TCACCTGTCACAGTTACAGCTCTTGCTCATCCTCCCTCTGGGCTACATCCAACTCCATCT ACTGCCCCAGGTCCCCATGTTCCATTAATGCCTCCATCTCCTCCATCACAAGTTATACCT GCTTCTGAGCCAAAGCGCCATCCATCAACCCTACCTGTAATCAGTGATGCCAGGAGTGTG CTACTGGAAGCAATACGAAAAGGTATTCAGCTACGCAAAGTAGAAGAGCAGCGTGAACAG GAAGCTAAGCATGAACGCATTGAAAACGATGTTGCCACCATCCTGTCTCGCCGTATTGCT GTTGAATATAGTGATTCGGAAGATGATTCAGAATTTGATGAAGTAGATTGGTTGGAGTAA Clone variation with respect to NM_003931.2 5' Read Nucleotide >OriGene 5' read for NM_003931 unedited Sequence: NGGGTCGTTTTTGTATACGACTCCTATAGGCGGCCGCGNATTCGGCACGAGGCTAGCTTC GGTACTCTGACACCTTCTCTTGCACTTGCGGATGATGAACTGGAATAACGATGAAAGAAA GCACATCCGATCTCAACATTCACGTCCTGCCCTATAACCGATTAATTAATTGATCCCCAG CTAGACTAGTGTTGGAGAAATCAGCATGTTAAAACAACTGTTGATGATAGCTGTTGGAGT AAAGTTGCAGTGGAAGCTATGGCTGCAAAATCGTTAAAATCTTCAAGGTGAACTGGCACA AAGGTTAATCTCAAGATGCCGCTAGTGAAAAGAAACATCGATCCTAGGCACTTGTGCCAC ACAGCACTGCCTAGAGGCATTAAGAATGAACTGGAATGTGTAACCAATATTTCCTTGGCA AATATAATTAGACAACTAAGTAGCCTAAGTAAATATGCTGAAGATATATTTGGAGAATTA TTCAATGAAGCACATAGTTTTTCCTTCAGAGTCAACTCATTGCAAGAACGTGTGGACCGT TTATCTGTTAGTGTTACACAGCTTGATCCAAAGGAAGAAGAATTGTCTTTGCAAGATATA ACAATGAGGAAAGCTTTCCGAAGTTCTACAATTCAAGACCAGCAGCTTTTCGATCGCAAG ACTTTGCCTATTCCATTACAGGAGACGTACGATGTTTGTGAACAGCCTCCACCTCTCAAT ATACTCACTCCTTATAGAGATGATGGTAANAGAAGGTTCTGAAGTTNTATACCAATCCTT CGTATTTCTTTGATCTATGGAAAGAANNAATGTTGCAAGATACAGNAGGATAGAGGAAGG NAAAGAGGAAGCAGAAGCAGAAAATTCTAGATCGTCCTCATGAACCAGNANAAGTGCCAG AGCACCTC This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 2 / 3 WAVE 1 (WASF1) (NM_003931) Human Untagged Clone – SC117699 3' Read Nucleotide >OriGene 3' read for NM_003931 unedited Sequence: TGGACCGGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTAACTTTTAAAA TGAACCATTTATTAAATCAGACTGTTATTCTTAACAGTTATGTAAGTTACATGTATGTTT AAGTCAGAGTATTTCACATGGAAAAGTTTTTAACTCCTATAGGCAAGCAAAATCATATCA CACAATATATAAGTGGGAAGGGGATACTGCTAAACATTCAAATAAGGCAAGTATATAAAA ACAATAAAACAATAATGAAAAAATTCAAGCATTCCTTTAAGAGAATTCAACACTACAAGC TAAATGTACTTTCTGAGTGTATTCGTATAATCAAGGCAGTGTTTCTTCTTTTAAAACATC AGGAAATGGAATAAGGCTCATTAGTAGATACAGCTGCCCTCAAGATTTCAATTTCAGTTG CTTTCTTTAAATTAAAATTCACAAAGTACACAATTAAGATATATCAAAAAACTGAATCTG CTACTCTAACAACAGCTGTCCATGCTTAATACTTAGTGGTTTATTTGACCAAATTAGTCT TTTCAGGGGGAAAAAAAGATAAGCCACTGTAAAACATTCAGTTTGAAATGTATGCTAATA TTTTCCTTAAAAATCAAAAGTTATGGAGGAAAAGGGTCATTTATTATAAGGAAAAGAAAG CCAAACACTATAATGACCCAACATTTTCCAGGAACAAGCACCCCAAAGGACATTTGCATT CACCTTTGCAATATTATCAATGCCTTTTTCTTACTCCACCAATCTACTTCATCAAATTCT GAAACCTCTTCCGAAATACTATTTTCAACAGCTATACCGGTGAAACCAGGATGGTGGCCA CCATCGTCTCCAAAGGCCTCCATGCCTTACCTTCCTGTTCACCCTCGTTTTTTTATTTTG Restriction Sites: NotI-NotI ACCN: NM_003931 Insert Size: 2620 bp OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). RefSeq: NM_003931.2, NP_003922.1 RefSeq Size: 3230 bp RefSeq ORF: 1680 bp Locus ID: 8936 UniProt ID: Q92558 Domains: WH2 Protein Families: Druggable Genome Protein Pathways: Adherens junction, Fc gamma R-mediated phagocytosis, Regulation of actin cytoskeleton Gene Summary: The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longest transcript. This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 3 / 3.