sign in sign up
<<
Home , Heart transplantation

CHILDREN’S CENTER PUBLICATIONS http://www.lpch.org

Transplantation and Canter CE, Shaddy RE, Bernstein D, Hsu, DT, Chrisant MRK, Kirklin JK, Kanter KR, Higgins RSD, Blume ED, Rosenthal DN, Boucek MM, Uzark KC, Chin C, Chen G, Sequeria F, Berry G, Siehr S, Bernstein D, Rosenthal D, Friedman AH, Young JK. AHA Scientific Statement: Indications for Heart Reinhartz O, Tyan D. “Clinical Usefulness of a Novel C1q Assay to Detect Transplantation in Pediatric Heart Disease. Circulation, 2007; 115:658-676. IgG Antibodies Capable of Fixing Complement in Sensitized Pediatric Heart Transplant Patients.” J Heart Lung Transplant, 2011; 30:158-163. Bernstein D, Williams GE, Eisen H, Mital S, Wohlgemuth JG, Klinger TM, Fang KC, Kobashigawa J. Gene expression profiling distinguishes a molecular Staveski SL, Avery S, Rosenthal DN, Roth SJ, Wright GE, Comprehensive signature for grade 1B mild acute cellular rejection in cardiac allograft Interdisciplinary Care Coordination of Infants and Young Children on recipients. J. Heart Lung Transplant, 2007; 12:1270-80. Berlin Heart Ventricular Assist Devices. Journal of Cardiovascular Nursing, in press, 2011. Bernstein D, Naftel DC, Hsu DT, Addonizio LJ, Blume ED, Gamberg PL, Kirklin JK, Morrow WR. Outcome of listing for cardiac transplantation for Stein ML, Robbins R, Sabati A, Reinhartz O, Chin C, Liu E, Bernstein failed Fontan: a multi-institutional study. Circulation, 2006; 114:273-280. D, Roth SJ, Wright GE, Reitz B, Rosenthal DN. INTERMACS-defined Morbidity and Mortality Associated with Pediatric VAD Support at a Single Rosenthal D, Bernstein D. Pediatric mechanical circulatory support: challenges US Center: Stanford Experience. Circulation Heart Failure, 2010; 3:682-688. and opportunities (editorial). Circulation, 2006; 113:2266-2268.

Singh TP, Sleeper L, Lipshultz SL, Cinar A, Canter C, Webber SA, Bernstein D, Girnita DM, Webber SA, Ferrell R, Burckart GJ, Brooks MM, Duquesnoy R, Pahl E, Alvarez J, Towbin J, Colan SD. Association of left ventricular dilation at McDade KK, Chinnock R, Canter C, Addonizio L, Bernstein D, Kirklin JK, listing for heart transplant with post-listing and early post-transplant survival Girnita AL, Zeevi A. Gene Polymorphism Distribution Among Racial and in pediatric dilated . Circulation: Heart Failure, 2009; 2:591-8. Ethnic Groups May Contribute To Disparate Clinical Outcomes In Pediatric Heart Transplantation. J. Transplantation, 2006; 82:1774-80. Girnita DM, Webber SA, Ferrell R, Brooks MM, DeCroo1 S, Burckart G, Zdanowicz G, Chinnock R, Canter C, Addonizio L, Bernstein D, Kirklin JK, Chin C, Naftel D, Pahl E, Shankel T, Clark ML, Gamberg P, Kirklin J, Webber S. Naftel D, Smith L, Girnita AL, AZeevi A. Genotypic variation and phenotypic “Cardiac Retransplantation in : A Multi-Institutional Study” J Heart characterization of granzyme B gene polymorphisms. Transplantation, 2009; Lung Transplant, 2006; 25:1420-4. 87:1801-6. Tu W, Potena L, Stepick-Biek P, Liu L, Dionis KY, Luikart H, Fearon WF, Girnita DM, Brooks MM, Webber SA, Burckart GJ, Ferrell R, Zdanowicz G, Holmes TH, Chin C, Cooke JP, Valantine HA, Mocarski ES, Lewis DB. DeCroo S, Smith L, Chinnock R, Canter C, Addonizio L, Bernstein D, Kirklin “T-Cell Immunity to Subclinical Cytomegalovirus Infection Reduces Cardiac JK, Naftel D, Girnita AL, Zeevi A. Genetic Polymorphisms Impact the Risk Allograft Disease” Circulation, 2006; 114:1608-15. of Acute Rejection in Pediatric Heart Transplantation: A Multi-institutional Study. Transplantation, 2008; 85:1632-1639. Potena L, Holweg CT, Chin C, Luikart H, Weisshaar D, Narasimhan B, Fearon WF, Lewis DB, Cooke JP, Mocarski ES, Valantine HS. “Acute rejection and Bernstein D and Parisi F. The pediatric heart donor: evaluation of age, size, cardiac allograft is reduced by suppression of subclinical cause of death, donor heart function, and vitality. In Canter C and Kirklin cytomegalovirus infection.” Transplantation, 2006; 82:398-405. JK. Pediatric Heart Transplantation. ISHLT Monograph Series, Elsevier, Philadelphia, 2008. Ross M, Kouretas P, Reitz B, Robbins R, Shumway N, Harbi S, Miller J, Gamberg P, Chin C, Bernstein D. 10 and 20-year long-term survival after pediatric Chin C, Putri S, Gamberg P, Miller J, Shek J, Bernstein D, Perry S. Prevention of orthotopic heart transplantation. J. Heart Lung Transplant, 2006; 25:261-70. pediatric : atorvastatin. Pediatric Transplantation, 2008; 12:442-6. Cardiac Malaisrie, S., Pelletier, M., Yun, J., Sharma, K., Timek, T., Rosenthal, D., Wright, Sasaki T, Boni L, Riemer RK, Yeung JT, Ramamoorthy C, Beckman R, Gisner G., Robbins, R., Reitz, B. Pneumatic Paracorporeal Ventricular Assist Device C, Shuttleworth P, Hanley FL, Reddy VM. Cerebral oxygen metabolism in Infants and Children: Initial Stanford Experience. J Heart Lung Transplant, during total body flow and antegrade cerebral perfusion at deep and moderate 2008 Feb; 27(2):173-7. hypothermia. Artif Organs, 2010 Nov; 34(11):980-6.

Potena L, Fearon W, Sydow K, Holweg C, Luikart H, Chin C, Weisshaar D, Obayashi DY, Yeh J, Silverman NH, Hanley FL. Anomalous coronary arteries Mocarski E, Lewis D, Valantine H, Cooke J. “Asymmetric Dimethylarginine from the opposite sinus of Valsalva in asymptomatic siblings treated with and Cardiac Allograft Vasculopathy Progression: Modulation by Sirolimus” pulmonary arterial translocation. J Thorac Cardiovasc Surg., 2010 Dec; Transplantation, 2008, 85:827-833. 140(6):1430-2.

http://heartcenter.lpch.org CHILDREN’S HEART CENTER PUBLICATIONS http://www.lpch.org

Cardiac Surgery (Cont’d) Reinhartz O, Reddy VM, Petrossian E, MacDonald M, Lamberti JJ, Roth SJ, Wright GE, Perry SB, Suleman S, Hanley FL. Homograft valved right Martin MH, Perry SB, Prochazka JV, Hanley FL, Silverman NH. Surgical to conduit as a modification of the . management of life threatening events caused by intermittent aortic Circulation, 2006 Jul 4; 114(1 Suppl):I594-9. insufficiency in a native valve: case report. J Cardiothorac Surg., 2010 Oct 29; 5:94. Reddy VM. for premature and low birth weight neonates. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu., 2001; 4:271-6. Sasaki T, Tsuda S, Riemer RK, Ramamoorthy C, Reddy VM, Hanley FL. Optimal flow rate for antegrade cerebral perfusion. J Thorac Cardiovasc Surg., Reddy VM, McElhinney DB, Amin Z, Moore P, Parry AJ, Teitel DF and 2010 Mar; 139(3):530-5. Hanley FL. Early and intermediate outcomes after repair of pulmonary atresia with ventricular septal defect and major aortopulmonary collateral arteries: Malhotra SP, Petrossian E, Reddy VM, Qiu M, Maeda K, Suleman S, MacDonald experience with 85 patients. Circulation, 2000; 101:1826-32. M, Reinhartz O, Hanley FL. Selective right ventricular unloading and novel technical concepts in Ebstein’s anomaly. Ann Thorac Surg., 2009 Dec; Reddy VM, McElhinney DB, Sagrado T, Parry AJ, Teitel DF and Hanley FL. 88(6):1975-81. Results of 102 cases of complete repair of congenital heart defects in patients weighing 700 to 2500 grams. J Thorac Cardiovasc Surg., 1999; 117:324-31. Malhotra SP, Hanley FL.Surgical management of pulmonary atresia with ventricular septal defect and major aortopulmonary collaterals: a protocol-based approach. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu., 2009; 145-51. Cisco MJ, Asija R, Dubin AM, Perry SB, Hanley FL, Roth SJ. Survival after extreme left atrial hypertension and pulmonary hemorrhage in an infant Amir G, Ma X, Reddy VM, Hanley FL, Reinhartz O, Ramamoorthy C, Riemer supported with extracorporeal membrane oxygenation for refractory atrial RK. Dynamics of human myocardial progenitor cell populations in the flutter. Pediatr Crit Care Med., 2010 Aug 5. [Epub ahead of print] neonatal period. Ann Thorac Surg., 2008 Oct; 86(4):1311-9. Lonyai A, Dubin AM, Feinstein JA, Taylor CA, Shadden SC. New insights into Malhotra SP, Hanley FL. Routine continuous perfusion for aortic arch pacemaker lead-induced venous occlusion: simulation-based investigation of reconstruction in the neonate. Semin Thorac Cardiovasc Surg Pediatr Card alterations in venous biomechanics. Cardiovasc Eng., 2010 Jun; 10(2):84-90. Surg Annu., 2008; 57-60. Ceresnak SR, Liberman L, Avasarala K, Tanel R, Motonaga KS, Dubin AM. Are Gulati R, Reddy VM, Culbertson C, Helton G, Suleman S, Reinhartz O, wide complex tachycardia algorithms applicable in children and patients with Silverman N, Hanley FL. Surgical management of coronary artery arising congenital heart disease? J Electrocardiol., 2010 Nov-Dec; 43(6):694-700. Epub from the wrong coronary sinus, using standard and novel approaches. J Thorac 2010 Apr 10. Cardiovasc Surg., 2007 Nov; 134(5):1171-8. Friedberg, MK, Dubin, AM, Van Hare, GF, McDaniel, GM, Niksch, A, Amir G, Ramamoorthy C, Riemer RK, Davis CR, Hanley FL, Reddy VM. Visual Rosenthal DN. Acute Effects of Single-Site Pacing From the Left and Right light spectroscopy reflects flow-related changes in brain oxygenation during Ventricle on Ventricular Function and Ventricular-Ventricular Interactions in regional low-flow perfusion and deep hypothermic circulatory arrest. J Thorac Children with Normal . Cong. Heart Dis., 2009; 4:356-61. Cardiovasc Surg., 2006 Dec; 132(6):1307-13. Friedberg MK, Dubin AM, Van Hare GF, McDaniel GM, Niksch A, Rosenthal Reinhartz O, Reddy VM, Petrossian E, MacDonald M, Lamberti JL, Roth DN. Pacing-induced electromechanical ventricular dyssynchrony does SJ, Wright GE, Perry SB, Suleman S, Hanley FL. Homograft Valved Right not acutely influence right ventricular function and global hemodynamics Ventricle to Pulmonary Artery Conduit as a Modification of the Norwood in children with normal hearts. J Cardiovasc Electrophysiol., 2009 May; Procedure. Circulation, 2006; 114(1 Suppl):I594-I599. 20(5):539-44. Petrossian E, Reddy VM, Collins KK, Culbertson CB, MacDonald MJ, Lamberti Dubin AM and Rosenthal, DN. Right Ventricular Resynchronization: Moving JJ, Reinhartz O, Mainwaring RD, Francis PD, Malhotra SP, Gremmels DB, Beyond Proof of Concept. J. Heart Rhythm, 2009; 6:857-9. Suleman S, Hanley FL. The extracardiac conduit Fontan operation using minimal approach extracorporeal circulation: early and midterm outcomes. Chanani NK, Chiesa NA, Dubin AM, Avasarala K, Van Hare GF, Collins KK. J Thorac Cardiovasc Surg., 2006 Nov; 132(5):1054-63. for atrioventricular nodal reentrant tachycardia in young patients: predictors of recurrence. Pacing Clin Electrophysiol., 2008 Sep; 31(9):1152-9.

http://heartcenter.lpch.org CHILDREN’S HEART CENTER PUBLICATIONS http://www.lpch.org

Electrophysiology (Cont’d) Bober M, Khan N, Kaplan J, Lewis K, Feinstein JA, Scott CI, Steinberg G. Majewski Osteodysplastic Primordial Dwarfism Type II (MOPD II): Friedberg MK, Silverman NH, Dubin AM, Rosenthal DN. Right ventricular Expanding the Vascular Phenotype. American Journal of Medical Genetics, mechanical dyssynchrony in children with hypoplastic left heart syndrome. 2010 Apr; 152A(4):960-5. J Am Soc Echocardiogr., 2007 Sep; 20(9):1073-9. Adatia I, Kothari SS, Feinstein JA. Pulmonary hypertension associated Friedberg MK, Silverman NH, Dubin AM, Rosenthal DN. Mechanical with congenital heart disease-A Global Perspective. Chest, 2010 Jun; 137 dyssynchrony in children with systolic dysfunction secondary to (6 Suppl):52S-61S. cardiomyopathy: a Doppler tissue and vector velocity imaging study. J Am Soc Echocardiogr., 2007 Jun; 20(6):756-63. Peng LF, Lock JE, Nugent AW, Jenkins KJ, McElhinney DB. Comparison of conventional and cutting balloon angioplasty for congenital and postoperative Dubin AM, Berul CI. Electrophysiological interventions for treatment of pulmonary vein stenosis in infants and young children. Cath and Cardiovascular congestive heart failure in pediatrics and congenital heart disease. Expert Rev Interventions, 2010 Jun 1; 75(7):1084-90. Cardiovasc Ther., 2007 Jan; 5(1):111-8. Newman B, Feinstein JA, Cohen RA, Feingold B, Kreutzer J, Patel H, Rosen J, Niksch AL, Dubin AM. Risk stratification in the asymptomatic child with Chan FP. Congenital Extrahepatic Portosystemic Shunt Associated with Left Wolff-Parkinson-White syndrome. Isomerism. Pediatr Radiol., 2010 Jan 13. [Epub]

Dubin AM, Janousek J, Rhee E, Strieper M, Cecchin F, Law I, Shannon K, Marsden AL, Bernstein AJ, Reddy VM, Shadden S, Spilker RL, Chan FP, Taylor Temple J, Rosenthal E, Zimmerman FJ, Davis AM, Karpawich PP, Shah, M, CA, Feinstein JA. Evaluation of a Novel Y-Shaped Extracardiac Fontan Baffle Vetter VL, Snyder C, Stephenson E, Kertesz NJ, Emmel M, Al Ahmed A, Using Computational Fluid Dynamics. J Thorac Cardiovasc Surg., 2009 Feb; Kanter R, Batran AJ, Collins KK. Resynchronization in Pediatric 137(2):394-403.e2. and Congenital Heart Disease Patients; A Multicenter Study. Journal of the American College of , 2005; 46:2277-83. Haddad F, Zamanian R, Beraud A, Schnittger I, Feinstein JA, Yang P, Peterson T, Doyle R, Rosenthal DN. A Novel Non-Invasive Method of Estimating Dubin AM, Berul CI, Bevilacqua LM, Collins KK, Etheridge SP, Fenrich AL, Pulmonary in Patients with Pulmonary Arterial Friedman RA, Hamilton RM, Schaffer MS, Shah M, Silka MJ, Van Hare GF, Hypertension. J Am Soc Echocardiogr., 2009 May; 22(5):523-9. Kertesz NJ. The Use of Implantable Cardioverter Defibrillators in Pediatric awaiting Heart Transplantation. Journal of Cardiac Failure, 2003; 9:375-9. Pickard SS, Feinstein JA, Pophat RA, Huang L, Dutta S. Short- and Long-Term Outcomes of Necrotizing Enterocolitis in Infants with Congenital Heart Dubin AM, Feinstein JA, Reddy VM, Hanley F, MD, Van Hare GF, Rosenthal Disease. Pediatrics, 2009 May; 123(5):e901-6. DN. Electrical Resynchronization: A Novel Therapy for the Failing Right Ventricle. Circulation, 2003; 107:2287-89. Feinstein JA, Gatzoilis MA. Pulmonary Hypertension Associated With Congenital Heart Disease: Use of Magnetic Resonance Imaging and Interventional Cardiology/Catheterization Computed Tomography. Cardiol Young, 2009 May; 19 Suppl 1:16-22. Coogan JS, Chan FP, Taylor CA, Feinstein JA. Computational fluid De Jesus Perez VA, Haddad F, Vagelos RH, Fearon W, Feinstein J, Zamanian RT. dynamicsimulations of aortic coarctation comparing the effects of surgical Angina associated with left main coronary artery compression in pulmonary and stentbased treatments on aortic compliance and ventricular workload. hypertension. J Heart Lung Transplant., 2009 May; 28(5):527-30. CatheterCardiovasc Interv., 2010 Nov 8. [Epub ahead of print] Kim HJ, Vignon-Clementel IE, Figuero CA, LaDisa JF, Jansen KE, Tang BT, Fonte TA, Chan FP, Tsao PS, Feinstein JA, Taylor CA. Three- Feinstein JA, Taylor CA. On coupling a lumped parameter heart model and dimensional Hemodynamic Conditions in the Human Pulmonary Arteries a three-dimensional finite element model. Ann Biomed Eng., 2009 Nov; under Resting and Exercise Conditions. Epub, 2010 Jul 17. 37(11):2153-69. Epub 2009 Jul 17.

Lonyai A, Dubin AM, Feinstein JA, Shadden SC. New Insights Into Pacemaker Rodgers GP, Conti JB, Feinstein JA, Griffin BP, Kennett JD, Shah S, Walsh Lead-Induced Venous Occlusion: Simulation-Based Investigation of MN, Williams ES and Williams JL. 2009 survey results and recommendations: Alterations in Venous Biomechanics. Annals of Biomed Eng., 2010 Jun; addressing the cardiology workforce crisis: a report of the ACC Board of 10(2):84-90. Trustees Workforce Task Force. J Am Coll Cardiol., 2009 Sep 22; 54(13):1195-208. Williams GC, Maan H, Ramamoorthy C, Kamra K, Bratton SL, Bair E, Kuan CC, Hammer GB, Feinstein JA. Perioperative Complications in Children with Pulmonary Hypertension Undergoing General Anesthesia with Ketamine. Paediatr Anaesth, 2010; 20(1):28-37.

http://heartcenter.lpch.org CHILDREN’S HEART CENTER PUBLICATIONS http://www.lpch.org

Interventional Cardiology/Catheterization (Cont’d) Reinhartz O, Reddy VM, Petrossian E, Suleman S, Mainwaring RD, Rosenthal DN, Feinstein JA, Gulati R, Hanley FL. Unifocalization of Major Marsden AL, Feinstein JA, Taylor CA. A Computational Framework for Aortopulmonary Collaterals in Single Ventricle Patients. Ann Thorac Surg., Derivative-Free Optimization of Cardiovascular Geometries. Comput Meth 2006 Sep; 82(3):934-8; discussion 938-9. App Mech Eng., 2008 Apr 1; 197(21):1890-1895. Cheng, CP, Taur, AS, Lee GS, Goris ML, Feinstein, JA. Relative Lung Perfusion Sutton NJ, Peng L, Lock JE, Lang P, Marx GR, Curran TJ, O’Neill J, Picard ST, Distribution in Normal Subjects: Observations and Clinical Implications. Rhodes J. Effect of Pulmonary Artery Angioplasty on Exercise Function after Congenit Heart Dis., 2006;1:210–216. Repair of Tetralogy of Fallot. Am Heart J., 2008; 155(1):182-6. Cheng CWB, Lee DP, Rosenthal DN, Feinstein JA. Percutaneous Transluminal Vlahos AP, Feinstein JA, Schiller NB, Silverman NH. Extension of Doppler Coronary Angioplasty in a Two Month Old With Coronary Stenosis Derived Echocardiographic Measures of Pulmonary Vascular Resistance to Presenting as Congenital Cardiomyopathy: Acute Results and 3 Year Follow Patients with Moderate or Severe Pulmonary Vascular Disease. J Am Soc Up. Catheter Cardiovasc Interv., 2006 Oct; 68(4):632-6. Echocardiogr., 2008 Jun; 21(6):711-4. Peng LF, McElhinney DB, Nugent AW, Powell AJ, Marshall AC, Bacha EA, Marsden AL, Vignon-Clementel IE, Chan F, Feinstein JA, Taylor CA. Effects Lock JE. Endovascular stenting of obstructed right ventricle-to-pulmonary of Exercise and Respiration on Hemodynamic Efficiency in CFD Simulations artery conduits: a fifteen-year experience. Circulation, 2006; 113:2598-2605. of the Total Cavopulmonary Connection. Ann Biomed Eng., 2007 Feb; 35(2):250-63. Cardiac Anesthesia Friedberg MK, Feinstein JA, Rosenthal DN. Non-invasive Assessment Sasaki T, Boni L, Riemer RK, Yeung JT, Ramamoorthy C, Beckman R, Gisner of Pulmonary Arterial Capacitance by . J Am Soc C, Shuttleworth P, Hanley FL, Reddy VM. Cerebral oxygen metabolism Echocardiogr., 2007 Feb; 20(2):186-90. during total body flow and antegrade cerebral perfusion at deep and moderate hypothermia. Artif Organs, 2010 Nov; 34(11):980-6. Spilker RL, Feinstein JA, Parker DW, Reddy VM, Taylor CA. Morphometry- Based Impedance Boundary Conditions for Patient-Specific Modeling of Sasaki T, Tsuda S, Riemer RK, Ramamoorthy C, Reddy VM, Hanley FL. Blood Flow in Pulmonary Arteries. Ann Biomed Eng., 2007 Apr; 35(4):546-59. Optimal flow rate for antegrade cerebral perfusion. J Thorac Cardiovasc Surg., 2010 Mar; 139(3):530-5. Jenkins KJ, Correa A, Feinstein JA, Botto L, Daniels SR, Elixson M, Warnes CA, Webb CL. Non-inherited Risk Factors for Congenital Heart Defects: Current Piehl EA, Foley L, Beckey VE, Wise-Faberowski L. Sevoflurane in a Developing Knowledge. Circulation, 2007 Jun 12; 115(23):2995-3014. Rat Brain Model: The Effect on GABAA Subunit Composition. J Neurosurg Anesthesiol, 2010 Jul; 22(3):220-9. Williams GD, Philip BM, Chu LF, Boltz MG, Kamra K, Terwey H, Hammer GB, Perry SB, Feinstein JA, Ramamoorthy C. Ketamine Does Not Increase Standing JF, Hammer GB, Sam WJ, Drover DR. Population pharmacokinetic- Pulmonary Vascular Resistance in Children with Pulmonary Hypertension pharmacodynamic modeling of the hypotensive effect of remifentanil in infants Undergoing Sevoflurane Anesthesia and Spontaneous Ventilation. Anesth undergoing cranioplasty. Pediatr Anesth, 2010; 20:7-18. Analg., 2007; 105:1578-1584. Williams G, Maan H; Ramamoorthy C, Kamra K, Bratton S, Bair E, Kuan Cheng CW, Lee DP, Rosenthal DN, Bernstein D, Feinstein JA. Percutaneous C, Hammer G, Feinstein J. Perioperative complications in children with Transluminal Coronary Angioplasty in a Two Month Old With Coronary pulmonary hypertension undergoing general anesthesia with ketamine. Stenosis Presenting as Congential Cardiomyopathy: Acute and Intermediate- Pediatr Anesth., 2010, 20:1, 28-37. Term Results. Cathet Cardiovasc Intervent., 2006; 68:632-6. Ramamoorthy C, Haberkern CM, Bhananker SM; Domino KB, Posner KL, Feinstein JA, Kim N, Reddy VM, Perry SB. Percutaneous Pulmonary Valve Campos JS, Morray JP. Anesthesia-Related Cardiac Arrest in Children with Placement in a 10-month-old Patient Using a Hand Crafted Stent-Mounted Heart Disease: Data from the Pediatric Perioperative Cardiac Arrest (POCA) Porcine Valve. Catheter Cardiovasc Interv., 2006; 67(4):644-9. Registry. Anesth. Analg., 2010; 20:28-37.

Friedberg MK, Feinstein JA, Rosenthal DN. A Novel Catherization-Derived, Wise- Faberowski L, Warner DS, Spasjovic I, Batinic-Haberle I. The effects of Echo-Applied Method for Estimation of Pulmonary Arterial Diastolic and Mn(III) ortho N-alkylpyridyl- and diortho N, N’-imidazolylporphyrins on Mean Pressure. J Am Soc Echocardiogr., 2006 May; 19(5):559-62. Oxygen and Glucose Deprivation-Induced Cell Death in Mixed Neuronal/ Glial Cortical Cell Cultures. J Biochem. Free Rad Res, 2009; 40:329-39.

http://heartcenter.lpch.org CHILDREN’S HEART CENTER PUBLICATIONS http://www.lpch.org

Cardiac Anesthesia (Cont’d) Newman B, Feinstein JA, Cohen RA, Feingold B, Kreutzer J, Patel H, Chan FP. Congenital extrahepatic portosystemic shunt associated with heterotaxy and Wise-Faberowski L, Robinson PN, Beckey VE, Warner DS. Oxygen and polysplenia. Pediatr Radiol., 2010 Jul; 40(7):1222-30. Glucose Deprivation in an Organotypic Hippocampal Slice Model of the Developing Rat Brain: Effects on N-methyl-d-aspartate Subunit Composition. Talluto C and Silverman NH. Aortic and mitral valve stenosis with Anesth Analg., 2009; 109:205-210. regurgitation: Not due to rheumatic heart disease. Echocardiography., 2010. [E-pub ahead of print] Sam WJ, Hammer GB, Drover DR. Population pharmacokinetics of remifentanil in infants and children undergoing cardiac surgery. BMC Lew C, Alley MTa, Spielman DM, Bammer R, Chan FP. Breathheld Anesthesiology, 2009; 9:5-38. autocalibrated phase-contrast imaging. J Magn Reson Imaging, 2010 Apr; 31(4):1004-14. Williams GD, Ramamoorthy C, Pentcheva K, Boltz MG, Kamra K, Reddy VM. A randomized, controlled trial of aprotinin in neonates undergoing open-heart Marsden AL, Reddy VM, Shadden SC, Chan FP, Taylor CA, Feinstein JA. A new surgery. Paediatr Anaesth., 2008 Sep; 18(9):812-9. multiparameter approach to computational simulation for Fontan assessment and redesign. Congenit Heart Dis., 2010 Mar; 5(2):104-17. Hammer GB, Drover DR, Cao H, Jackson E, Williams GD, Ramamoorthy C, Van Hare GF, Niksch A, Dubin AM. The effects of dexmedetomidine on cardiac Punn R and Silverman NH. Cardiac Segmental Analysis in Left Ventricular: electrophysiology in children. Anesth Analg., 2008 Jan; 106(1):79-83. Noncompaction: Experience in a Pediatric Population. J Am Soc Echocardiogr., 2010; 23(1):46–53. Williams GD, Philip BM, Chu LF, Boltz MG, Kamra K, Terwey H, Hammer GB, Perry SB, Feinstein JA, Ramamoorthy C. Ketamine does not increase Punn R, Behzadian F, Tacy T. Annular Tilt as a Screening Test for Right pulmonary vascular resistance in children with pulmonary hypertension Ventricular Enlargement in Patients with Tetralogy of Fallot. Journal of the undergoing sevoflurane anesthesia and spontaneous ventilation. Anesth Analg., American Society of Echocardiography, in press, 2010. 2007 Dec; 105(6):1578-84. Chan FP. MR and CT imaging of the pediatric patient with structural heart Williams GD, Ramamoorthy C. Brain monitoring and protection during disease. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu., 2009; 99-105. pediatric cardiac surgery. Semin Cardiothorac Vasc Anesth, 2007 Mar; 11(1):23-33. Marsden AL, Bernstein AJ, Reddy VM, Shadden SC, Spilker RL, Chan FP, TaylorCA, Feinstein JA. Evaluation of a novel Y-shaped extracardiac Fontan Amir G, Ramamoorthy C, Riemer RK, Davis CR, Hanley FL, Reddy VM. Visual baffle using computational fluid dynamics. J Thorac Cardiovasc Surg., 2009 light spectroscopy reflects flow-related changes in brain oxygenation during Feb;137(2):394-403.e2. regional low-flow perfusion and deep hypothermic circulatory arrest. J Thorac Cardiovasc Surg., 2006 Dec; 132(6):1307-13. Sarnari R, Yousef Kamal R, Friedberg MK, Silverman NH. Doppler Assessment of the Ratio of the Systolic to Diastolic Duration in Normal Children: Williams GD, Ramamoorthy C, Chu L, Hammer GB, Kamra K, Boltz Relation to Heart Rate, Age and Body Surface Area. J Am Soc Echocardiogr., MG, Pentcheva K, McCarthy JP, Reddy VM. Modified and conventional 2009; 22:928–32. ultrafiltration during pediatric cardiac surgery: clinical outcomes compared. J Thorac Cardiovasc Surg., 2006 Dec; 132(6):1291-8. Friedberg MK, Silverman NH, Moon-Grady AJ, Tong E, Nourse J, Sorenson B, Lee J, Hornberger LK. Prenatal detection of congenital heart disease. J Pediatr., Heninger C, Ramamoorthy C, Amir G, Kamra K, Reddy VM, Hanley FL, 2009; 155(1):26–31. Brock-Utne JG. Esophageal saturation during antegrade cerebral perfusion: a preliminary report using visible light spectroscopy. Paediatr Anaesth., 2006 Kemna MS, Murphy DJ, Silverman NH. Screening for Aortic Root Dilation in Nov; 16(11):1133-7. Marfan Syndrome Using the Ratio of the Aortic Root to Descending Aortic Diameters in Children. J Am Soc Echocardiogr, 2009; 22(10):1111–13. Echocardiography/Imaging Mahle WT, John JB, Silverman NH. The history of the development of pediatric Tang BT, Fonte TA, Chan FP, Tsao PS, Feinstein JA, Taylor CA.Three- Echocardiology. Cardiol Young, 2009; 19 (suppl 2) 26–34. dimensional hemodynamics in the human pulmonary arteries under resting and exercise conditions. Ann Biomed Eng., 2011 Jan; 39(1):347-58. Vlahos AP, Feinstein JA, Schiller NB, Silverman NH. Extension of Doppler- derived echocardiographic measures of pulmonary vascular resistance to Schroeder AR, Axelrod DM, Silverman NH, Rubesova E, Merkel E, Roth SJ. A patients with moderate or severe pulmonary vascular disease. J Am Soc continuous heparin infusion does not prevent catheter-related in Echocardiography, 2008 June 21; (6):711–24. infants post cardiac surgery. Pediatr Crit Care Med., 2010 Jul; 11(4):489-95.

http://heartcenter.lpch.org CHILDREN’S HEART CENTER PUBLICATIONS http://www.lpch.org

Echocardiography/Imaging (Cont’d) Ciotti, GR, Vlahos AP, Silverman NH. Morphology and Function of the Bicuspid Aortic Valve with and without coarctation of the aorta in the young. Soslo JH, Friedberg MK, Silverman, NH. Idiopathic premature closure of the Am J Cardiol., 2006; 98:1096-102. ductus arteriosus: An indication for early delivery. Echocardiography, 2008; Friedberg MK, Silverman NH. Cardiac ventricular diastolic and systolic 25(6):650–2. duration in children with heart failure secondary to idiopathic . Am J Cardiol., 2006; 97:1:101-5. Mahle WT, Martinez R, Silverman N, Cohen MS, Anderson RH. Anatomy, echocardiography, and surgical approach to double right ventricle. Cardiol Friedberg MK, Chang IL, Silverman NH, Ramamoorthy C, Chan FP. Images Young, 2008; 18(Suppl. 3):39–51. in cardiovascular medicine. Near sudden death from cardiac lipoma in an adolescent. Circulation, 2006; 113:21:e778-9. Bernheimer J, Friedberg M, Chan F, and Silverman NH. Echocardiographic Diagnosis of Persistent Fifth Aortic Arch. Echocardiography, 2007; 24:258–62. Kim N, Friedberg MK, Silverman NH. Diagnosis and prognosis of fetuses with double outlet right ventricle. Prenat Diagn., 2006; 26:740-5. Friedberg MK, Nancy Kim, MD, and Silverman NH. Atrioventricular septal defect recently diagnosed by fetal echocardiography: Echocardiographic Friedberg MK, Silverman NH. The systolic to diastolic duration ratio in features, associated anomalies, and outcomes. Congenital Heart Disease, 2007; children with heart failure secondary to restrictive cardiomyopathy. J Am Soc 2:110–4. Echocardiography, 2006; 19:11:1326-3. Lee HC, Silverman N, Hintz SR. Diagnosis of patent ductus arteriosus by a neonatologist with a compact, portable ultrasound machine. J Perinatol, 2007; Cardiac Intensive Care 27:291–296. Staveski S, Avery S, Rosenthal DN, Roth SJ, Wright GE. Comprehensive Friedberg MK, Silverman NH. The systolic to diastolic duration ratio in Interdisciplinary Care Coordination of Infants and Young Children on Berlin children with hypoplastic left heart syndrome: A novel Doppler index of right Heart Ventricular Assist Devices. Journal of Cardiovascular Nursing, 2010 Nov ventricular function. J Am Soc Echocardiography, 2007; 20:749-55. 19. [Epub ahead of print]

Friedberg MK, Silverman NH, Dubin AM, Rosenthal DN. Mechanical Schroeder AR, Axelrod DM, Silverman NH, Merkel E, Reddy VM, dyssynchrony in children with systolic dysfunction secondary to Hanley FL, Roth SJ. A Continuous Heparin Infusion Does Not Prevent cardiomyopathy: A Doppler tissue and vector velocity imaging study. J Am Soc Catheter-Related Thrombosis in Infants Following Cardiac Surgery. Echocardiography, 2007; 20:756-63. Pediatric Critical Care Medicine, 2010; 11(4):489-95.

Gulati R, Reddy VM, Culbertson, C, Helton G, Suleman S, Reinhartz O, Mackie AS, Gauvreau K, Booth KL, Newburger JW, Roth SJ. Hemodynamic Silverman NH, Hanley Fl. Surgical management of coronary artery arising Correlates of Serum Cortisol in Neonates after . from the wrong Coronary Sinus, using standard and novel approaches. Pediatric Critical Care Medicine, 2010 Oct 1. [Epub ahead of print]. J Theroa Cardiovasc Surg., 2007; 134:1171-8. Cisco MJ, Asija R, Dubin AM, Perry SB, Hanley FL, Roth SJ. Survival After McMullan DM, Reddy VM, Gottiebson WM, Silverman NH, Perry SB, Chan Extreme Left Atrial Hypertension and Pulmonary Hemorrhage in an Infant F, Hanley FL, Riemer RK. Morphological studies of pulmonary arteriovenous Supported with Extracorporeal Membrane Oxygenation for Intractable Atrial shunting in a lamb model of superior cavopulmonary anastomosis. Pediatric Flutter. Pediatric Critical Care Medicine, 2010 Aug 5. [Epub ahead of print]. Cardiology, 2007 Jul; 29(4):706-12. Stein ML, Robbins R, Sabati A, Reinhartz O, Chin C, Liu E, Bernstein D, Roth Lew CD, Alley MT, Bammer R, Spielman DM, Chan FP. Peak velocity and flow SJ, Wright GE, Reitz B, Rosenthal DN. INTERMACS-defined Morbidity quantification validation for sensitivity-encoded phase-contrast MR imaging. and Mortality Associated with Pediatric VAD Support at a Single US Center: Acad Radiol., 2007 Mar; 14(3):258-69. Stanford Experience. Circulation Heart Failure, 2010; 3:682-688.

Marsden AL, Vignon-Clementel IE, Chan FP, Feinstein JA, Taylor CA. Effects Newburger JW, Jonas RA, Soul J, Kussman BD, Bellinger DC, Laussen PC, of exercise and respiration on hemodynamic efficiency in CFD simulations Robertson R, Mayer JE, del Nido PJ, Bacha EA, Forbess JM, Pigula F, Roth of the total cavopulmonary connection. Ann Biomed Eng., 2007 Feb; SJ, Visconti KJ, du Plessis AJ, Farrell DM, McGrath E, Rappaport LA, Wypij 35(2):250-63. D. Randomized Trial of Hematocrit 25% versus 35% during Hypothermic Cardiopulmonary Bypass in Infant Heart Surgery. Journal of Thoracic and Greenway SC, Bradley TJ, Caldarone CA, Silverman NH, Hanley FL, Smallhorn Cardiovascular Surgery, 2008; 135:347-354. JF. Aortopulmonary window with anomalous origin of the right coronary artery from the pulmonary artery: two cases highlighting the importance of complete pre-operative echocardiographic evaluation of the coronary arteries in all conotruncal anomalies. Eur J Echocardiography, 2006; 5:379-82.

http://heartcenter.lpch.org CHILDREN’S HEART CENTER PUBLICATIONS http://www.lpch.org

Cardiac Intensive Care (Cont’d) Zamanian RT, Hansmann G, Snook S, Lilienfeld D, Rappaport KM, Reaven GM, Rabinovitch M, Doyle RL. resistance in pulmonary arterial Sharek PJ, Parast LM, Leong K, Coombs J, Earnest K, Sullivan J, hypertension. Eur Respir J, 2009; 33:318-24. Frankel LR, Roth SJ. Effect of a Rapid Response Team on Hospital-wide Mortality and Code Rates Outside the ICU in a Children’s Hospital. De Jesus Perez VA, Alastalo T-P, Wu JC, Axelrod JD, Cooke JP, Amieva M, Journal of the American Medical Association, 2007; 298:2267-2274. Rabinovitch M. Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-b-catenin and Wnt-RhoA-Rac1 pathways. J Cell Chock VY, Reddy VM, Bernstein D, Madan A. Neurologic events in neonates Biol., 2009; 184(1):83-99. treated surgically for congenital heart disease. J. Perinat., 2006; 26:237-242. Ying L, Lau A, Alvira CM, West R, Cann GM, Zhou B, Kinnear C, Jan E, Basic Science Sarnow P, Van De Rijn M, Rabinovitch M. LC3 mediated fibronectin mRNA translation induces fibrosarcoma growth by increasing connective tissue Mokres LM, Parai K, Hilgendorff A, Ertsey R, Alvira CM, Rabinovitch M, Bland growth factor. J Cell Sci., 2009; 122(Pt 9):1441-51. RD. Prolonged Mechanical Ventilation with Air Induces Apoptosis and Causes Failure of Alveolar Septation and Angiogenesis in Lungs of Newborn Mice. Wu JC, Chruscinski A, De Jesus Perez VA, Singh H, Pitsiouni M, Rabinovitch Am J Physiol Lung Cell Mol Physiol., 2010 January; 298(1):L23-L35. (PMCID: M, Utz PJ, Cooke JP. Cholinergic modulation of angiogenesis: Role of the 7 PMC2806196) nicotinic acetylcholine receptor. J Cell Biochem., 2009; 108(2):433-46.

Nakahira K, Haspel JA, Rathinam VA, Lee SJ, Dolinay T, Lam HC, Englert JA, Spiekerkoetter E, Guignabert C, De Jesus Perez V, Alastalo TP, Powers JM, Rabinovitch M, Cernadas M, Kim HP, Fitzgerald KA, Ryter SW, Choi AM. Wang L, Lawrie A, Ambartsumian N, Schmidt AM, Berryman M, Ashley RH, Autophagy proteins regulate innate immune responses by inhibiting the release Rabinovitch M. S100A4 and Bone Morphogenetic Protein-2 Codependently of mitochondrial DNA mediated by the NALP3 inflammasome. Nat Immunol., Induce Vascular Smooth Muscle Cell Migration via Phospho-Extracellular 2010 Dec 12. [Epub ahead of print]. (PMID: 21151103) Signal-Regulated Kinase and Chloride Intracellular Channel 4. Circ Res., 2009; 105(7):639-47. Iqbal, Z, Cejudo-Martin P, De Brouwer A, van der Zwaag B, Ruiz-Lozano P, Scimia MC, Lindsey JD, Albrecht B, Megarbane A, Alanay Y, Ben-Neriah Z, Guignabert C, Alvira CM, Alastalo T-P, Sawada H, Hansmann G, Zhao M, Amenduni M, Artuso R, Veltman JA, van Beusekom E, Oudakker A, Millan J-L, Wang L, El-Bizri N, Rabinovitch M. Tie2-Mediated Loss of Peroxisome Hennekam R., Hamel B, Courtneidge SA, van Bokhoven H. Disruption Of The Proliferator-Activated Receptor-{gamma} in Mice Causes PDGF-Receptor Podosome Adaptor Protein Tks4 (Sh3pxd2b) Causes the Skeletal Dysplasia, {beta}-Dependant Pulmonary Arterial Muscularization. Am J Physiol Lung Eye And Cardiac Abnormalities Of Frank-Ter Haar Syndrome. Am J Hum Cell Mol Physiol., 2009 Dec; 297(6):L1082-90. Genet., 2010; 86(2):254-61. Buechling T, Akasaka T, Vogler G, Ruiz-Lozano P, Karen Ocorr, Bodmer R. De Jesus Perez VA, Alastalo TP, Wu JC, Axelrod JD, Cooke JP, Amieva Non-autonomous modulation of heart rhythm, contractility and morphology M, Rabinovitch M. Bone morphogenetic protein 2 induces pulmonary in adult fruit flies. Developmental Biology, 2009; 328(2):483-92. angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways. J Cell Biol., 2009 Jan 12; 184(1):83-99. Fink M, Callol-Massot C, Chu A, Ruiz-Lozano P, Izpisua Belmonte JC, Giles W, Bodmer R, Ocorr K. A new method for detection and quantification of Charo, DN, Ho, M, Fajardo G, Kawana M, Kundu RK, Sheikh AY, Finsterbach heartbeat parameters in Drosophila, zebrafish, and embryonic mouse hearts. T, Leeper NJ, Ernst KV, Chen M, Ho YD, Chun HJ, Bernstein D, Ashley EA, Biotechniques, 2009; 46(2):101-13. Quertermous T. Endogenous Regulation of Cardiovascular Function by Apelin-APJ. Amer. J. Physiol., 2009; 297:H1904-13. Huang X, Gao X, Diaz-Trelles R, Ruiz-Lozano P, Wang Z. Coronary development is regulated by ATP-dependent SWI/SNF chromatin remodeling Spiekerkoetter E, Guignabert C, De Jesus Perez V, Alastalo TP, Powers JM, component BAF180. Developmental Biology, 2008 Jul 15; 319(2):258-66. Wang L, Lawrie A, Ambartsumian N, Schmidt AM, Berryman M, Ashley RH, Rabinovitch M. S100A4 and bone morphogenetic protein-2 codependently Sridurongrit S, Larsson J, Schwartz R, Ruiz-Lozano P, Kaartinen V. Signaling via induce vascular smooth muscle cell migration via phospho-extracellular signal- the TGF-ß type I receptor Alk5 in heart development. Developmental Biology, regulated kinase and chloride intracellular channel 4. Circ Res., 2009 Sep 25; 2008 Oct 1; 322(1):208-18 105(7):639-47. Norman JJ, Mukandan V, Bernstein D, Pruitt BL. Microsystems for biomedical Maxwell AJ, Tsao PS, Bernstein D, Cooke JP. Hypercholesterolemia impairs measurements. Pediatr. Res., 2008; 63:576-583. exercise capacity in mice. Vascular Med., 2009; 14:249-57.

http://heartcenter.lpch.org CHILDREN’S HEART CENTER PUBLICATIONS http://www.lpch.org

Basic Science (Cont’d) Bland RD, Xu L, Ertsey R, Rabinovitch M, Albertine KH, Wynn KA, Kumar V, Ryan RM, Swartz DD, Csiszar K, Fong KS. Dysregulation of pulmonary Urashima T, Zhao M, Wagner R, Fajardo G, Farhani S, Quertermous T, Bernstein elastin synthesis and assembly in preterm lambs with chronic lung disease. D. Molecular and physiologic characterization of RV remodeling in a murine Am J Physiol Lung Cell Mol Physiol., 2007; 292(6):L1370-84. model of pulmonary stenosis. Amer. J. Physiol., 2008; 295:H1351-1368. Bland RD, Mokres LM, Ertsey R, Jacobson BE, Jiang S, Rabinovitch M, Xu L, Spiekerkoetter E, Alvira CM, Kim YM, Bruneau A, Pricola KL, Wang L, Shinwell ES, Zhang F, Beasley MA. Mechanical ventilation with 40% oxygen Ambartsumian N, Rabinovitch M. Reactivation of gammaHV68 induces reduces pulmonary expression of genes that regulate lung development and neointimal lesions in pulmonary arteries of S100A4/Mts1-overexpressing mice impairs alveolar septation in newborn mice. Am J Physiol Lung Cell Mol in association with degradation of elastin. Am J Physiol Lung Cell Mol Physiol., Physiol. 2007; 283(5):L1099-110. 2008; 294(2):L276-89. El-Bizri N, Wang L, Merklinger SL, Guignabert C, Desai T, Urashima T, Daley E, Emson C, Guignabert C, De Waal Malefyt R, Louten J, Kurup VP, Sheikh AY, Knutsen RH, Mecham RP, Mishina Y, Rabinovitch M. Smooth Hogaboam C, Taraseviciene-Stewart L, Voelkel NF, Rabinovitch M, Grunig E, muscle protein 22alpha-mediated patchy deletion of Bmpr1a impairs cardiac Grunig G. Pulmonary arterial remodeling induced by a Th2 immune response. contractility but protects against pulmonary vascular remodeling. Circ Res J Exp Med, 2008; 205(2):361-72. 2007; 102(3):380-8.

Hansmann G, De Jesus Perez VA, Alastalo, T, Alvira CM, Guignabert C, Carè A, Catalucci D, Felicetti F, Bonci D, Addario A, Gallo P, Bang M-L, Bekker JM, Schellong S, Urashima T, Wang L, Morrell NW, Rabinovitch M. An Segnalini P, Gu Y, Dalton N.D, Latronico M.V.G, Høydal M, Autore C, Russo antiproliferative BMP-2/PPARgamma/apoE axis in human and murine SMCs M.A., Dorn 2nd , G.W., Ellingsen Ø, Ruiz-Lozano P, Peterson K.L., Croce and its role in pulmonary hypertension. J Clin Invest., 2008; 118(5):1846-57. CM., Peschle C, Condorelli G. MicroRNA-133 controls cardiac myocyte hypertrophy. Nature Medicine, 2007; 13(5):613-8. Fan X, Krieg S, Kuo CJ, Wiegand SJ, Rabinovitch M, Druzin ML, Brenner RM, Giudice LC, Nayak NR. VEGF blockade inhibits angiogenesis and Llagostera E, Catalucci D, Marti L, Liesa M, Camps M, Ciaraldi TP, Kond reepithelialization of endometrium. FASEB J., 2008; 22(10):3571-80. R, Reddy S, Dillman WH, Palacin M, Zorzano A, Ruiz-Lozano P, Gomis R, Kaliman P. Role of Myotonic Dystrophy Protein Kinase (DMPK) in Glucose El-Bizri N, Guignabert C, Wang L, Cheng A, Stankunas K, Chang CP, Mishina Homeostasis and Muscle Insulin Action. PLoS ONE, 2007 Nov 7; 2(11):e1134. Y, Rabinovitch M. SM22alpha-targeted deletion of bone morphogenetic protein receptor 1A in mice impairs cardiac and vascular development, and Zamora M, Manner J, Ruiz-Lozano P. Epicardium-derived progenitor cells influences organogenesis. Development, 2008; 135(17):2981-91. require ß-catenin for coronary artery formation. Proc. Natl. Acad. Sci., 2007 Nov 13; 104(46):18109-18114. Bland RD, Ertsey R, Mokres LM, Xu L, Jacobson BE, Jiang S, Alvira CM, Rabinovitch M, Shinwell ES, Dixit A. Mechanical ventilation uncouples Ecker P, Lin C-C, Powers J, Kobilka BK, Dubin AM, Bernstein D. Effect of synthesis and assembly of elastin and increases apoptosis in lungs of newborn targeted deletions of ß1 and ß2 adrenergic receptor subtypes on heart rate mice. Prelude to defective alveolar septation during lung development? Am J variability. Amer. J. Physiol., 2006; 290:H192-9. Physiol Lung Cell Mol Physiol., 2008; 294(1):L3-14. Fajardo G, Zhao M, Powers J, Bernstein D. Differential cardiotoxic/cardio- Cann GM, Guignabert C, Ying L, Deshpande N, Bekker JM, Wang L, Zhou B, protective effects of ß-adrenergic receptor subtypes in myocytes and fibroblasts Rabinovitch M. Developmental expression of LC3alpha and beta: absence of in doxorubicin cardiomyopathy. J. Mol. Cell. Card., 2006; 40:375-383. fibronectin or autophagy phenotype in LC3beta knockout mice. Dev Dyn., 2008; 237(1):187-95. Wang J, Hoshijima M, Lam JT, Zhou Z, Jokiel A, Dalton ND, Hultenby K, Ruiz- Lozano P, Ross Jr., J Tryggvason K. and Chien KR. Cardiomyopathy associated Alvira CM, Abate A, Yang G, Dennery PA, Rabinovitch M. Nuclear with microcirculation dysfunction in laminin α4 chain deficient mice. J. Biol. factor-kappaB activation in the neonatal mouse lung protects against Chem., 2006; 281(1):213-220. Lipopolysaccharide-induced inflammation. Am J Respir Crit Care Med., 2007; 175(8):805-15. St. Amand T.R, Lu J.T., Zamora M, Gu Y, Stricker J, Hoshijima M, Ross JJ, Chien K.R., Ruiz-Lozano P. Distinct roles of HF-1b/Sp4 in ventricular and Hansmann G, Wagner RA, Schellong S, de Jesus Perez VA, Urashima T, Wang neural crest cells lineages affect cardiac conduction system development. L, Sheikh AY, Suen RS, Stewart DJ, Rabinovitch M. Pulmonary arterial Developmental Biology, 2006; 291(2):208-17. hypertension is linked to insulin resistance and reversed by PPAR-gamma activation. Circulation, 2007; 115(10):1275-84.

http://heartcenter.lpch.org