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Suppl 1.1 All Data Dimethyl Labled Fasta headers Protein names Gene names Uniprot Ratio H/L normalized exp01 Ratio H/L normalized exp02 Ratio H/L normalized exp03 Ratio H/L normalized exp04 Ratio H/L normalized exp05 Ratio H/L normalized exp06 Ratio H/L normalized exp07 Ratio H/L normalized exp08 Ratio H/L normalized exp09 Ratio H/L normalized exp10 Ratio H/L normalized exp11b Ratio H/L normalized exp12b Peptides exp01 Peptides exp02 Peptides exp03 Peptides exp04 Peptides exp05 Peptides exp06 Peptides exp07 Peptides exp08 Peptides exp09 Peptides exp10 Peptides exp11b Peptides exp12b Unique peptides exp01 Unique peptides exp02 Unique peptides exp03 Unique peptides exp04 Unique peptides exp05 Unique peptides exp06 Unique peptides exp07 Unique peptides exp08 >sp|P01876|IGHA1_HUMAN Ig alpha-1 chain C region OS=Homo sapiens GN=IGHA1 PE=1 SV=2Ig alpha-1 chain C region IGHA1 P01876 1,90 0,62 2,03 12,53 11,35 0,80 1,87 0,60 0,88 1,60 1,33 1,34 7 6 11 8 10 6 8 8 4 3 7 7 3 3 5 4 5 3 4 3 >sp|P02647|APOA1_HUMAN Apolipoprotein A-I OS=Homo sapiens GN=APOA1 PE=1 SV=1;>tr|F8W696|F8W696_HUMAN Truncated apolipoprotein A-I OS=Homo sapiens GN=APOA1 PE=1 SV=1Apolipoprotein A-I;Truncated apolipoprotein A-I APOA1 P02647 1,71 1,13 0,77 1,73 0,89 1,12 0,61 0,84 1,53 1,46 1,16 0,86 17 16 17 18 16 14 13 16 17 13 14 17 17 16 17 18 16 14 13 16 >sp|P01024|CO3_HUMAN Complement C3 OS=Homo sapiens GN=C3 PE=1 SV=2Complement C3;Complement C3 beta chain;Complement C3 alpha chain;C3a anaphylatoxin;Acylation stimulating protein;Complement C3b alpha chain;Complement C3c alpha chain fragment 1;Complement C3dg fragment;Complement C3g fragment;Complement C3d fragment;Complement C3f fragment;Complement C3c alpha chain fragment 2C3 P01024 1,37 1,54 1,23 1,45 0,92 1,52 1,19 0,89 1,17 0,96 1,29 0,97 53 51 50 53 47 48 44 57 47 30 38 40 50 46 44 50 42 42 38 50 >sp|P04217|A1BG_HUMAN Alpha-1B-glycoprotein OS=Homo sapiens GN=A1BG PE=1 SV=4;>sp|P04217-2|A1BG_HUMAN Isoform 2 of Alpha-1B-glycoprotein OS=Homo sapiens GN=A1BG;>tr|M0R009|M0R009_HUMAN Alpha-1B-glycoprotein (Fragment) OS=Homo sapiens GN=A1BG PE=4 SV=2Alpha-1B-glycoprotein A1BG P04217 1,24 1,35 0,61 1,22 1,33 1,21 0,58 1,14 2,30 1,13 1,17 0,79 9 9 9 10 9 10 10 9 10 8 5 6 9 9 9 10 9 10 10 9 >sp|P02763|A1AG1_HUMAN Alpha-1-acid glycoprotein 1 OS=Homo sapiens GN=ORM1 PE=1 SV=1Alpha-1-acid glycoprotein 1 ORM1 P02763 1,22 1,39 0,60 1,02 1,03 2,20 0,89 1,31 1,00 1,14 1,17 0,93 6 7 5 6 6 6 6 6 6 6 7 7 5 6 4 5 5 5 5 5 >sp|P00747|PLMN_HUMAN Plasminogen OS=Homo sapiens GN=PLG PE=1 SV=2Plasminogen;Plasmin heavy chain A;Activation peptide;Angiostatin;Plasmin heavy chain A, short form;Plasmin light chain BPLG P00747 1,19 0,62 0,83 1,55 1,43 1,01 0,76 0,87 0,74 1,09 0,77 7 4 6 6 3 5 4 3 3 2 2 3 7 4 6 6 3 5 4 3 >sp|P01042-2|KNG1_HUMAN Isoform LMW of Kininogen-1 OS=Homo sapiens GN=KNG1;>sp|P01042-3|KNG1_HUMAN Isoform 3 of Kininogen-1 OS=Homo sapiens GN=KNG1;>sp|P01042|KNG1_HUMAN Kininogen-1 OS=Homo sapiens GN=KNG1 PE=1 SV=2Kininogen-1;Kininogen-1 heavy chain;T-kinin;Bradykinin;Lysyl-bradykinin;Kininogen-1 light chain;Low molecular weight growth-promoting factorKNG1 P01042-2 1,16 1,34 0,98 1,33 1,06 1,73 0,97 0,87 1,18 1,31 1,17 0,69 11 8 8 10 9 10 10 10 11 4 8 8 11 8 8 10 9 10 10 10 >sp|P35908|K22E_HUMAN Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens GN=KRT2 PE=1 SV=2;>P35908 SWISS-PROT:P35908 Tax_Id=9606 Gene_Symbol=KRT2 Keratin, type II cytoskeletal 2 epidermalKeratin, type II cytoskeletal 2 epidermal KRT2 P35908 1,09 0,33 4,50 0,17 1,27 0,54 1,62 0,55 0,57 0,59 2,20 1,47 12 15 33 24 19 15 10 11 12 15 11 7 7 7 20 15 11 8 5 4 >tr|d6RF35|d6RF35_HUMAN Vitamin d-binding protein OS=Homo sapiens GN=GC PE=1 SV=1;>sp|P02774|VTdB_HUMAN Vitamin d-binding protein OS=Homo sapiens GN=GC PE=1 SV=1;>sp|P02774-3|VTdB_HUMAN Isoform 3 of Vitamin d-binding protein OS=Homo sapiens GN=GC;>tr|d6RBJVitamin d-binding protein GC d6RF35 1,05 1,03 0,96 1,09 1,21 1,08 0,92 1,10 1,05 1,20 1,08 0,81 21 24 17 24 20 20 21 25 23 18 10 12 20 23 17 23 20 20 21 24 >sp|P01008|ANT3_HUMAN Antithrombin-III OS=Homo sapiens GN=SERPINC1 PE=1 SV=1Antithrombin-III SERPINC1 P01008 1,00 1,32 1,22 1,19 1,11 1,25 0,83 1,01 1,42 1,05 1,16 0,54 14 13 12 15 13 13 13 11 11 9 11 11 14 13 12 15 13 13 13 11 >sp|P01011|AACT_HUMAN Alpha-1-antichymotrypsin OS=Homo sapiens GN=SERPINA3 PE=1 SV=2;>tr|G3V3A0|G3V3A0_HUMAN Alpha-1-antichymotrypsin OS=Homo sapiens GN=SERPINA3 PE=3 SV=1Alpha-1-antichymotrypsin;Alpha-1-antichymotrypsin His-Pro-less SERPINA3 P01011 0,98 1,67 0,73 0,92 0,83 1,29 0,96 1,76 1,28 1,32 1,49 0,80 11 14 14 13 13 12 12 13 13 8 10 10 11 14 14 13 13 12 12 13 >sp|P04196|HRG_HUMAN Histidine-rich glycoprotein OS=Homo sapiens GN=HRG PE=1 SV=1Histidine-rich glycoprotein HRG P04196 0,98 1,08 0,59 0,73 0,67 0,91 1,02 1,14 1,05 0,74 0,79 0,50 7 4 2 5 5 3 4 3 3 3 6 5 7 4 2 5 5 3 4 3 >sp|P01859|IGHG2_HUMAN Ig gamma-2 chain C region OS=Homo sapiens GN=IGHG2 PE=1 SV=2Ig gamma-2 chain C region IGHG2 P01859 0,97 0,46 0,77 1,13 0,87 2,13 3,33 0,53 1,91 3,09 1,26 3,73 11 10 11 8 10 10 10 11 10 11 9 10 5 4 5 3 4 4 4 5 >sp|P02768|ALBU_HUMAN Serum albumin OS=Homo sapiens GN=ALB PE=1 SV=2;>P02768-1 SWISS-PROT:P02768-1 Tax_Id=9606 Gene_Symbol=ALB Isoform 1 of Serum albumin precursor;>tr|B7WNR0|B7WNR0_HUMAN Serum albumin OS=Homo sapiens GN=ALB PE=1 SV=1;>tr|H0YA55|H0YA55_HUMSerum albumin ALB P02768 0,95 0,98 0,98 0,98 1,10 0,95 0,95 1,10 0,94 1,15 1,12 0,83 46 46 45 43 45 45 46 45 47 46 62 57 41 41 40 38 40 40 41 40 >sp|P02765|FETUA_HUMAN Alpha-2-HS-glycoprotein OS=Homo sapiens GN=AHSG PE=1 SV=1;>tr|C9JV77|C9JV77_HUMAN Alpha-2-HS-glycoprotein OS=Homo sapiens GN=AHSG PE=1 SV=1Alpha-2-HS-glycoprotein;Alpha-2-HS-glycoprotein chain A;Alpha-2-HS-glycoprotein chain BAHSG P02765 0,94 1,24 1,03 1,16 2,09 0,90 1,19 1,04 1,16 1,33 0,86 0,56 9 9 9 9 9 9 9 8 9 8 4 4 8 8 8 8 8 8 8 7 >sp|P01009|A1AT_HUMAN Alpha-1-antitrypsin OS=Homo sapiens GN=SERPINA1 PE=1 SV=3;>sp|P01009-2|A1AT_HUMAN Isoform 2 of Alpha-1-antitrypsin OS=Homo sapiens GN=SERPINA1;>sp|P01009-3|A1AT_HUMAN Isoform 3 of Alpha-1-antitrypsin OS=Homo sapiens GN=SERPINA1Alpha-1-antitrypsin;Short peptide from AAT SERPINA1 P01009 0,93 0,86 0,87 0,75 1,31 1,05 0,97 1,20 0,88 1,22 1,22 0,69 19 18 19 18 19 17 18 18 17 14 27 26 19 18 19 18 19 17 18 18 >sp|P19652|A1AG2_HUMAN Alpha-1-acid glycoprotein 2 OS=Homo sapiens GN=ORM2 PE=1 SV=2Alpha-1-acid glycoprotein 2 ORM2 P19652 0,92 1,37 0,91 1,06 0,99 2,40 0,70 0,69 0,92 1,21 1,22 0,55 6 6 5 5 6 5 5 6 3 5 7 6 5 5 4 4 5 4 4 5 >sp|P25311|ZA2G_HUMAN Zinc-alpha-2-glycoprotein OS=Homo sapiens GN=AZGP1 PE=1 SV=2;>tr|C9JEV0|C9JEV0_HUMAN Zinc-alpha-2-glycoprotein OS=Homo sapiens GN=AZGP1 PE=2 SV=1Zinc-alpha-2-glycoprotein AZGP1 P25311 0,84 1,39 0,99 1,27 1,07 1,26 0,86 1,19 0,78 1,37 1,08 1,09 8 8 7 11 8 7 6 7 5 3 9 11 8 8 7 11 8 7 6 7 >sp|P01019|ANGT_HUMAN Angiotensinogen OS=Homo sapiens GN=AGT PE=1 SV=1Angiotensinogen;Angiotensin-1;Angiotensin-2;Angiotensin-3;Angiotensin-4;Angiotensin 1-9;Angiotensin 1-7;Angiotensin 1-5;Angiotensin 1-4AGT P01019 0,81 1,90 0,88 1,47 1,11 1,73 0,94 0,67 0,83 1,36 1,00 0,77 4 6 3 4 4 4 3 5 4 2 4 4 4 6 3 4 4 4 3 5 >sp|P06727|APOA4_HUMAN Apolipoprotein A-IV OS=Homo sapiens GN=APOA4 PE=1 SV=3Apolipoprotein A-IV APOA4 P06727 0,80 1,29 2,06 2,66 0,73 0,94 1,03 0,95 1,67 1,46 1,55 0,97 16 13 11 17 12 11 12 13 11 5 27 25 15 12 10 16 11 10 11 12 >sp|P13645|K1C10_HUMAN Keratin, type I cytoskeletal 10 OS=Homo sapiens GN=KRT10 PE=1 SV=6;>P13645 SWISS-PROT:P13645 Tax_Id=9606 Gene_Symbol=KRT10 Keratin, type I cytoskeletal 10Keratin, type I cytoskeletal 10 KRT10 P13645 0,78 0,30 3,66 0,21 1,39 0,49 1,55 0,47 0,37 0,37 1,47 1,10 14 18 26 23 20 16 13 11 14 19 13 13 13 15 21 17 17 13 12 9 >sp|P00738|HPT_HUMAN Haptoglobin OS=Homo sapiens GN=HP PE=1 SV=1;>tr|J3QR68|J3QR68_HUMAN Haptoglobin (Fragment) OS=Homo sapiens GN=HP PE=1 SV=1;>tr|H0Y300|H0Y300_HUMAN Haptoglobin OS=Homo sapiens GN=HP PE=1 SV=4;>tr|J3QLC9|J3QLC9_HUMAN Haptoglobin (FragmenHaptoglobin;Haptoglobin alpha chain;Haptoglobin beta chain;Haptoglobin-related proteinHP;HPR P00738 0,75 5,85 1,32 0,16 5,37 0,33 2,41 0,16 0,36 3,53 0,36 0,26 17 9 16 11 10 7 16 12 12 13 5 13 17 9 16 11 10 7 16 12 >sp|P01834|IGKC_HUMAN Ig kappa chain C region OS=Homo sapiens GN=IGKC PE=1 SV=1Ig kappa chain C region IGKC P01834 0,73 0,76 0,92 0,73 0,91 1,89 3,17 0,86 0,90 0,92 0,91 1,34 5 5 5 5 5 5 5 5 5 5 4 6 5 5 5 5 5 5 5 5 >sp|P02790|HEMO_HUMAN Hemopexin OS=Homo sapiens GN=HPX PE=1 SV=2Hemopexin HPX P02790 0,71 1,19 0,98 0,99 0,82 1,21 1,06 0,96 1,15 1,09 0,96 0,99 13 17 13 13 14 14 13 14 12 11 14 14 13 17 13 13 14 14 13 14 >sp|P35527|K1C9_HUMAN Keratin, type I cytoskeletal 9 OS=Homo sapiens GN=KRT9 PE=1 SV=3;>P35527 SWISS-PROT:P35527 Tax_Id=9606 Gene_Symbol=KRT9 Keratin, type I cytoskeletal 9;>tr|K7EQQ3|K7EQQ3_HUMAN Keratin, type I cytoskeletal 9 OS=Homo sapiens GN=KRT9 PE=1Keratin, type I cytoskeletal 9 KRT9 P35527 0,68 0,95 0,80 0,53 1,02 5,29 0,85 0,77 0,35 0,38 0,63 4,40 7 18 16 15 11 20 9 8 7 16 10 7 6 17 15 14 10 20 8 8 >sp|P00450|CERU_HUMAN Ceruloplasmin OS=Homo sapiens GN=CP PE=1 SV=1Ceruloplasmin CP P00450 0,66 1,66 0,81 0,79 0,83 0,87 1,61 0,95 0,86 1,04 1,26 1,30 19 23 20 20 21 23 21 20 18 20 26 24 1 1 1 1 1 1 1 1 >tr|B4E1H2|B4E1H2_HUMAN Plasma protease C1 inhibitor OS=Homo sapiens GN=SERPING1 PE=2 SV=1;>sp|P05155|IC1_HUMAN Plasma protease C1 inhibitor OS=Homo sapiens GN=SERPING1 PE=1 SV=2;>tr|B4E1F0|B4E1F0_HUMAN Plasma protease C1 inhibitor OS=Homo sapiens GN=SERPIPlasma protease C1 inhibitor SERPING1 B4E1H2 0,61 1,09 0,76 0,57 0,82 0,74 1,79 0,82 1,06 0,75 0,89 0,97 4 10 9 9 10 10 10 9 7 6 11 9 4 10 9 9 10 10 10 9 >sp|P04264|K2C1_HUMAN Keratin, type II cytoskeletal 1 OS=Homo
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