Genome

Gene Expression Profiling Analysis Reveals Fur Development in Rex Rabbits (Oryctolagus cuniculus)

Journal: Genome

Manuscript ID gen-2017-0003.R2

Manuscript Type: Article

Date Submitted by the Author: 31-Jul-2017

Complete List of Authors: Zhao, Bohao; Yangzhou University Chen, Yang; Yangzhou University Yan, Xiaorong ; Yangzhou University Hao, Ye; YangzhouDraft University Zhu, Jie; Yangzhou University Weng, Qiiaoqing; Zhejiang Yuyao Xinnong Rabbit Industry Co., Ltd. Wu, Xinsheng; Yangzhou University, College of Animal Science and Technology

Is the invited manuscript for consideration in a Special This submission is not invited Issue? :

Keyword: Chinchilla rex rabbit, fur development, key gene, transcriptome

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1 Gene Expression Profiling Analysis Reveals Fur Development in Rex

2 Rabbits ( Oryctolagus cuniculus )

3 BoHao Zhao 1, Yang Chen 1, XiaoRong Yan 1, Ye Hao 1, Jie Zhu 1, QiaoQing Weng 2, and

4 XinSheng Wu 1*

5 1 The Key Laboratory of Animal Genetics & Breeding and Molecular Design of Jiangsu Province,

6 College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, P.R.

7 China. ;

8 2 Zhejiang Yuyao Xinnong Rabbit Industry Co., Ltd., Yuyao, Zhejiang 315400, China

9 *Corresponding author Email: [email protected] 10 Draft

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11 Abstract

12 Fur is an important economic trait in rabbits. The identification of genes that

13 influence fur development and knowledge regarding the actions of these genes

14 provides useful tools for improving fur quality. However, the mechanism of fur

15 development is unclear. To obtain candidate genes related to fur development, the

16 transcriptomes of tissues from backs and bellies of Chinchilla rex rabbits were

17 compared. Of the genes analyzed, 336 showed altered expression in the two groups

18 (285 upregulated and 51 downregulated), P≤0.05, foldchange≥2 or ≤0.5). Using GO

19 and KEGG to obtain gene classes that were differentially enriched, we found several

20 genes to be involved in manyDraft important biological processes. In addition, we

21 identified several signaling pathways involved in fur development, including the Wnt

22 and MAPK signaling pathways, revealing mechanisms of skin and hair follicle

23 development, and epidermal cell and keratinocytes differentiation. The obtained rabbit

24 transcriptome and differentially expressed gene profiling data provided

25 comprehensive gene expression information for SFRP2, FRZB, CACNG1, SLC25A4

26 and SLC16A3. To validate the RNAseq data, the expression levels of eight

27 differentially expressed genes involved in fur development were confirmed by

28 qRTPCR. The results of rabbit transcriptomic profiling provide a basis for

29 understanding the molecular mechanisms of fur development.

30 Keywords

31 Chinchilla rex rabbit, fur development, key gene, transcriptome

32

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33 Introduction

34 The Chinchilla rex rabbit is an important rabbit breed with varied natural coat

35 colors; consumers highly appreciate the properties of rex furs, such as beauty, softness,

36 color, lightness, and warmth retention (Pan et al. 2015). The characteristics of

37 Chinchilla rex rabbit fur differs between the back and belly, especially the length and

38 diameter of the wools (Tao 2010).

39 In recent years, many studies have revealed the mechanisms of skin and fur

40 development. RNAseq was used to explore the mechanisms of keratinocyte

41 development in mouse skin, and transcription factor (TF) p63 was found to be highly 42 expressed in stratified epithelia, whichDraft affected the epidermal phenotype (Rizzo et al. 43 2014). Many genes involved in skin development, including those for transcription

44 factors and growth factors, have been identified in rex rabbits with the plaice

45 phenotype (Pan et al. 2015). In cashmere goats, genes related to hair follicle

46 development and cycling were identified in anagen, catagen and telogen stages by

47 transcriptomic investigation of fur development (Geng et al. 2013). It is generally

48 known that fur development is influenced by many factors, including the proliferation

49 of keratinocytes, development of the epidermis and hair follicle (HF) morphogenesis

50 (Danilenko et al. 1995). Multiple genes involved in HF morphogenesis, regulation of

51 proliferation, differentiation and migration of skin are controlled by members of the

52 Wnt signaling pathway, such as the frizzled and secreted frizzledrelated protein

53 (SFRP) families (Ehrlund et al. 2013; Kim and Yoon 2014). Epidermal growth factor

54 is regulated by the MAPK/ERK pathway and plays a vital role in the animal skin

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55 development, enhancing epidermal growth and keratinization, directly stimulating the

56 proliferation of epidermal cells and promoting keratinocyte proliferation and

57 migration. However, fur characteristics are different at different parts of an animal,

58 and the mechanism of fur development regulation is still unclear in rabbits.

59 Rabbit genome sequencing has been used to study the polygenerelated phenotypic

60 changes during rabbit domestication (Carneiro et al. 2014) and differential gene

61 expression in animal skin between anagen and telogen was shown by transcriptome

62 sequencing (Xu et al. 2013). In this study, the skin from the backs and bellies of

63 Chinchilla rex rabbits was collected, and gene expression profiling was used to obtain 64 the differentially expressed genesDraft related to the fur development. After functional 65 annotation, enrichment analysis and assessment of biological functions, candidate

66 genes were identified. These key genes were verified by quantitative realtime PCR.

67 The results obtained serve to improve our understanding of fur development and the

68 differential expression profiles of the candidate genes enable us to clarify the

69 mechanisms of fur development, providing a valuable theoretical basis for further

70 research on the hair and fur of animals.

71

72 Materials and methods

73 Ethics statement

74 All animal experiments were reviewed and approved by the Institutional Animal

75 Care and Use Committee of the School of Animal Science and Technology, Yangzhou

76 University, and performed in accordance with the Regulations for the Administration

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77 of Affairs Concerning Experimental Animals (China, 1988) and the Standards for the

78 administration of experimental practices (Jiangsu, China, 2008). All surgery was

79 performed according to recommendations proposed by the European Commission

80 (1997), and all efforts were made to minimize suffering of the animals.

81 Tissue collection

82 The Chinchilla rex rabbits used in the experiments were obtained from Zhejiang

83 Yuyao Xinnong Rabbit Co., Ltd. During our experiments, rabbits were raised in a

84 controlled environment and had free access to water and food. All rabbits were housed

85 in a suitable, clean and disease free environment, and a secure cage. The health of the 86 rabbits were monitored twice a Draftday (7 am and 6 pm) and recorded. Three healthy, 87 20dayold rabbits with the same fur traits were evaluated. Fur on the back (B group)

88 and belly (F group) were different. Three biological samples were taken for each of

89 the two groups (one sample of back and belly fur from each rabbit) to ensure the same

90 genetic background and fur phenotype in each group. After transfer to the laboratory,

91 skin tissue samples (1.5 cm 2) were collected from the back and belly of each rabbit.

92 Animals were anesthetized with by injection with 0.7% sodium pentobarbital solution

93 into the ear vein of the rabbits; in order to prevent bacterial infection iodine solution

94 was smeared on the resultant lesion. Fur was removed from the surface, and then the

95 skin was cut into pieces. The pieces were placed in tubes containing RNase,

96 immediately preserved in liquid nitrogen and stored at 70°C until use in subsequent

97 experiments.

98 RNA extraction, cDNA library construction, and Illumina sequencing

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99 Total RNA was extracted following the manufacturer’s instructions using the

100 mirVana™ miRNA isolation kit (Ambion); the integrity of the RNA was determined

101 with an Agilent Bioanalyzer 2100 (Agilent technologies, Santa Clara, CA, US) to

102 obtain a RNA Integrity Number (RIN). An RNeasy micro kit (Cat#74004, QIAGEN,

103 GmBH, Germany) was used to further purify the qualified total RNA, and DNA was

104 removed with the RNaseFree DNase set (QIAGEN, GmBH, Germany). RNA quality

105 was monitored using NanoDrop ND1000 and Agilent Bioanalyzer 2100. After RNA

106 extraction and purification, 3 g RNA was used for construction of the back and belly

107 cDNA libraries. Ribosomal RNA (rRNA) was depleted from the total RNA and the 108 remaining RNA was subsequentlyDraft fragmented. These steps were followed by first and 109 second cDNA strand synthesis, end repair, 3'end adenylation, adapter ligation, and

110 enrichment of the cDNA templates. Finally, the library concentration was determined

111 using a Qubit® 2.0 fluorometer and a Qubit™ dsDNA HS kit (Invitrogen). Cluster

112 generation was completed the sample library, and the first primers hybridized to cBot

113 matched the Illumina HiSeq 2500 platform. After cluster generation, the sequencing

114 reagent was prepared according to the HiSeq 2500 user guide using pairedend

115 technology. Sequencing was controlled by data collection software (Illumina, San

116 Francisco, USA) and the data were analyzed in real time.

117 Transcriptome mapping and analysis of differentially expressed genes

118 The cDNA library was sequenced using an Illumina HiSeq 2500 sequencing

119 platform. Original image files were obtained, and bases were called and filtered, after

120 which the results were stored in fastq format. The original sequencing reads were used

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121 for transcriptome sequencing analysis. As the raw reads contained sequences of low

122 quality, clean reads were obtained using fastx (version: 0.0.13), which included the

123 removal of lowquality sequence fragments, 3’ end bases that were 10 below the

124 quality score of Q=10 (Q =10log error_ratio ), adapter sequences, reads containing runs of

125 N’s blurs, and any sequences shorter than 20 nucleotides with low overall quality. We

126 then used the TopHat algorithm (version:2.0.9) (Trapnell et al. 2009) to map the clean

127 reads to the Oryctolagus cuniculus genome by spliced mapping, allowing two bases

128 of mispairing and multiple hits less than or equal to two, according to Ensembl

129 OryCun2.0. Gene expression was quantified using Cufflinks (version:2.1.1) (Trapnell 130 et al. 2010). Additionally, the fragmentsDraft per kilobase of exon model per million 131 mapped reads (FPKM) were defined as follows: transcript reads FPKM= ×10 9 transcript length × total mapped reads in run

132 The foldchange and Fishertest were used to analyze the differentially expressed

133 genes that were selected with a false discovery rate (FDR) of less than 0.05 and a

134 foldchange greater than or equal to 2 or less than or equal to 0.5.

135 Gene annotation and network analysis

136 The differentially expressed genes obtained from the two skin types were used for

137 functional annotation and mapped to Gene Ontology (GO; www.geneontology.org/)

138 terms and Kyoto Encyclopedia of Genes and Genomes (KEGG;

139 www.genome.jp/kegg/) pathways to identify pathways potentially associated with

140 skin development. P values less than or equal to 0.05 and FDR less than or equal to

141 0.05 were considered statistically significant. After comparing the hypergeometrics

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142 with the background of the genome, we screened the GO terms looking for significant

143 enrichment of the differentially expressed genes. P values correspond to differential

144 gene expression after Bonferroni correction, and corrected P values less than or equal

145 to 0.05 were the threshold for significance of differences in gene expression. The

146 STRING database was used to perform network analysis and the union of all

147 differentially expressed genes between the B and F groups was used to build the

148 network.

149 Quantitative real-time PCR confirmation of differentially expressed genes

150 To validate the sequencing data, eight known differentially expressed candidate 151 genes were selected for validationDraft by qRTPCR, which was performed on a 7500 152 realtime PCR system (Applied Biosystems) using the AceQ qPCR SYBR® Green

153 Master Mix (Vazyme) according to the manufacturer’s instructions. The primer

154 sequences are listed in Table 1. We chose the rabbit glyceraldehyde3phosphate

155 dehydrogenase (GAPDH) gene as an internal control. The results of the experiments

156 were normalized to the expression of the constitutive GAPDH gene. Quantitative

157 variation and relative foldchange were calculated based on the 2 –Ct method

158 (Schmittgen and Livak 2008). Error bars represent the mean ± S.D. as determined

159 using GraphPad Prism 5, and a paired ttest was performed to test significant

160 differences between the two groups using SPSS 21.0.

161 Western blotting

162 Protein lysates from six skin samples were obtained using RIPA Lysis Buffer

163 (PPLYGEN). Protein concentrations were determined with the Enhanced BCA Protein

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164 Kit (Beyotime). The protein lysates were diluted to 0.5g/L, and 2.5g protein was

165 detected and analyzed with the Wes automated Western blotting system (Protein

166 Simple) (Harris 2015). The following antibodies were used: 1:100 AntiGAPDH

167 mouse monoclonal antibody (Abcam), 1:50 AntiSFRP2 monoclonal antibody

168 (Sangon Biotech).

169 Results

170 Results of transcriptome sequencing

171 To evaluate whether the RNAseq data were sufficient for further analysis, their 172 global quality was firstly assessed.Draft After trimming clean reads were generated with a 173 ratio of greater than 85% for each sample (Table 2); and the total clean reads that

174 mapped to the rabbit genome had mapping ratios greater than 80% (Table 3). All

175 reads were deposited in the Short Read Archive (SRA) of the National Center for

176 Biotechnology Information (NCBI) under the accession number SRR3528284. We

177 then obtained the mapped read distribution, which showed whether the reads mapped

178 to genes, coding regions, splice sequences, intron sequences, intergenic regions, or

179 noncoding regions (5’UTR and 3’UTR, noncoding RNA regions) (Figure 1). Our

180 results showed that we were able to detect 17,327 expressed genes, including 8445

181 upregulated genes and 8882 downregulated genes (Table S1).

182 To identify the key differentially expressed genes, the parameters of a foldchange

183 greater than or equal to 2 or less than or equal to 0.5 and FDR less than or equal to

184 0.05 were used to further select the significantly differentially expressed genes. These

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185 cutoffs identified 285 upregulated genes and 51 downregulated genes (Table S2).

186 Volcano plots of differentially expressed genes were constructed to explore the

187 relationship between foldchange and significance as shown in Figure 2. This analysis

188 identified 336 genes that were significantly differentially expressed between the back

189 and belly regions of the rex rabbits.

190 Functional annotation of differentially expressed genes

191 GO functional enrichment and KEGG pathway analyses were performed to

192 determine the functions of the differentially expressed genes. According to the GO 193 analysis, categories of biologicalDraft process (n=563), molecular function (n=204), and 194 cellular component (n=132) contained 214 differentially expressed genes (Table S3),

195 which were all considered statistically significant (Figure S1). In the biological

196 process category, most GO terms focused on ion activity, development,

197 morphogenesis, cellular processes, biological regulation, and metabolic processes. In

198 the molecular function category, a high proportion of the GO terms were related to

199 binding, activity regulation, enzymatic activity, and ionic equilibrium. In the cellular

200 component category, we found the terms Z disc, I band, muscle contraction, myofibril,

201 titin binding, and M band sarcoplasmic reticulum showed the greatest enrichment of

202 differentially expressed genes. These GO terms revealed the biological functions of

203 the genes. According to the GO analysis, many GO terms were related to the functions

204 of skin and epithelial cells, such as epithelial cell proliferation, regulation of cell

205 proliferation, skin development and regulation of cell development. This suggests that

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206 the genes in these GO categories may play roles in fur development. We then

207 identified the fur development related genes from the GO terms and their distribution

208 in the molecular function categories (Figure 3).

209 Meanwhile, KEGG pathway analysis identified 66 differentially expressed genes

210 (Table S4), and results of the KEGG enrichment are shown in Figure S2. Analysis of

211 all the KEGG signaling pathways showed a definite relationship between several

212 pathways, such as the Wnt and MAPK signaling pathways. We identified the SFRP2

213 and FRZB genes from the Wnt signaling pathway (Figure S3) and calcium channel,

214 voltagedependent, beta 1 subunit (CACNB1), voltagedependent calcium channel 215 gamma1 subunit (CACNG1), andDraft calcium channel, voltagedependent, L type, alpha 216 1S subunit (CACNA1S) from the MAPK signaling pathway. These genes were found

217 to influence HF and skin development related signaling pathways, suggesting that

218 these genes may play a role in fur development (Chu et al. 2014; Fuchs and Raghavan

219 2002; Kim and Yoon 2014).

220 Network analysis of differentially expressed gene interactions

221 To explore interactions of the differentially expressed genes, RNAseq data was

222 used to construct a differentially expressed gene interaction network. We identified

223 interacting partners of the differentially expressed genes using the STRING database,

224 which predicts functional associations between proteins (Figure 4).

225 Validation of differentially expressed genes

226 To confirm our RNAseq results, qRTPCR was performed on samples from the 11

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227 backs and bellies of the rabbits. Eight target genes were selected and specific primers

228 were designed for validation. As shown in Figure 5A, we found that FRZB, SFRP2,

229 DUSP26, PTP4A3, EN1, and CACNA1S were upregulated, and HBB1 and MRPL36

230 were downregulated by qRTPCR. The protein levels of SFRP2 among the six

231 samples were further assessed by Western blotting, and we found the highest

232 expression of the SFRP2 protein in the back group (Figure 5B). These data indicate

233 that the results from the transcriptome study are consistent with the overall changes in

234 expression of the differentially expressed genes.

235 Draft 236 Discussion

237 The characteristics of fur are different on different body parts of Chinchilla rex

238 rabbits, especially the back and belly (Tao 2010). Fur development is regulated by

239 many factors, such as rearing conditions, nutrition, environment, and gene regulation

240 (Harkness et al. 2013; McNitt et al. 2013). Our study revealed several fur

241 development related genes by transcriptomics, and the functional enrichment and

242 pathway analysis of these genes will contribute to our understanding of the

243 mechanisms of fur development.

244 The Wnt signaling pathway plays an indispensable role at various stages during

245 tissue regeneration and skin development (StoickCooper et al. 2007). In this pathway,

246 Wnt proteins are important in conveying inductive signals between the mesenchyme

247 of follicles and the follicular epithelium. As a family of secreted glycoproteins, Wnts

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248 also play roles in embryonic development and maintenance of homeostasis by

249 regulating migration, differentiation, proliferation and apoptosis of cells in mature

250 tissues (Fujimaki et al. 2015; Millar 2002). Several transcription factors have been

251 identified that regulate the differentiation of keratinocytes via the MAPK signaling

252 pathway (Eckert and Welter 1996), which governs many cellular processes, including

253 cell fate, proliferation, differentiation, homeostasis, and survival in all eukaryotes

254 (Whelan et al. 2012). For example, activator protein I is a keratinocyte transcription

255 factor that plays a crucial role in the regulation of epidermal differentiation and the

256 expression of genes in the MAPK pathway (Briata et al. 1993; Eckert and Welter 1996; 257 Smeyne et al. 1992). Draft 258 Many genes that are related to fur development such as Secreted frizzledrelated

259 protein 2 (SFRP2) and Frizzledrelated protein (FRZB) are glycoproteins that are

260 involved in the processes of development and disease in diverse cells and tissues

261 (Ezan et al. 2004; Hoang et al. 1996; Kim and Yoon 2014). SFRP2 inhibited mouse

262 keratinocyte proliferation in the catagen phase and was regarded as a Wnt inhibitor in

263 HFs. In the back skin of mice, the Wnt target genes Ccnd1 and Cmyc, were shown to

264 have an inverse relationship between the two genes and SFRP2 throughout the HF

265 cycle, while SFRP2 may inhibit the proliferation of keratinocytes in the catagen phase

266 (Kim and Yoon 2014). Moreover, SFRP2 can control cell apoptosis and fate, and

267 mediate regulation of the Wnt pathway that has effects on intestinal epithelial cells

268 (Skah et al. 2015). However, the SFRP2 protein was highly expressed in the back

269 group in our study; suggesting that the protein product of SFRP2 acted as an activator

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270 in skin development. This means that SFRP2 could play a positive role in controlling

271 epidermal cell and keratinocyte differentiation.

272 FRZB (also called SFRP3 or Fritz) is a member of secreted frizzledrelated protein

273 family, which includes secreted proteins (SFRP15) that bind and inhibit Wnts

274 (Ehrlund et al. 2013; Ladher et al. 2000). As an antagonist of Wnt proteins in chick

275 development, FRZB inhibited the activity of Xwnt8 during the gastrula stages

276 (Ladher et al. 2000). With the activation of downstream targets of the pathway, a

277 knockdown of FRZB upregulated the Wnt/β ‑catenin pathway (Qin et al. 2014). In this

278 study, FRZB was upregulated in the back group, suggesting that FRZB may promote 279 the growth of HFs and skin development.Draft However many previous studies have 280 regarded FRZB as an inhibitor, although it is probably an activator that influences the

281 target genes in the Wnt pathway.

282 In our study, the fur phenotypes, such as the length and diameter of the wool, were

283 different between the back and belly skin of rex rabbits. These differences may be

284 influenced by the structure of HF and skin, especially the development of epidermal

285 cells and keratinocytes. Bioinformatic analysis revealed that genes in the Wnt

286 signaling pathway may have effects on the development of HF and skin. We also

287 found that SFRP2 mRNA and protein were highly expressed in the back group,

288 leading to the longer, thicker and greater density than belly group.

289 The regulation of fur development related genes involves the differential expression

290 of genes associated with many biological signaling pathways. The mechanism of HF

291 and skin development will be clarified by functional studies of the candidate genes.

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292 Therefore, with RNA sequencing and function analysis, the functions of these key

293 genes, such as SFRP2 and FRZB, should be verified by further study including their

294 function in hair cycle regulation, differentiation of keratinocytes and their role in the

295 Wnt pathway.

296

297 Conclusion

298 Gene expression profiling analysis was used to assess fur development in Chinchilla

299 rex rabbits. This study found several genes associated with HF and skin development,

300 including SFRP2, FRZB, CACNG1, CACNB1, CACNA1S, PTPLA, PTP4A3, TTN, 301 DUSP26, EN1, MT3, SLC25A4Draft and SLC16A3. The mechanisms regulating fur 302 development are complex, and fur development related genes should be studied

303 further.

304

305 Acknowledgments

306 This work was supported by the Modern Agricultural Industrial System Special

307 Funding (CARS441) and the Priority Academic Program Development of Jiangsu

308 Higher Education Institutions (2011137).

309

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395 Figure Legends

396 Figure 1. Mapped region distribution of each sample. Mapped read distribution for

397 each sample, showing the percentage of reads that mapped to each type of genomic

398 region (genes, coding regions, splice sequences, intron sequences, intergenic regions,

399 and noncoding regions (5’UTR and 3’UTR)) in the Ensembl OryCun2.0 database.

400 Figure 2. Volcano plot of differentially expressed genes. Red dots show

401 upregulated genes, green dots show downregulated genes, and two blue lines show a

402 2fold change in expression (P=0.05).

403 Figure 3. GO enrichment of genes related to fur development. Within the 404 molecular function category, we Draftidentified genes induced by fur development in rex 405 rabbits. GO categories included biological processes, cellular component, and

406 molecular function.

407 Figure 4. Diagram of the interaction network. Thicker lines show stronger

408 interactions of differentially expressed genes and their partner genes.

409 Figure 5. Analysis of differentially expressed genes involved in the regulation of

410 fur development in rabbits. (A) The mRNA levels of FRZB, SFRP2, DUSP26,

411 PTP4A3, EN1, CACNA1S, HBB1 and MRPL36 between back and belly groups. The

412 expression level of genes in the back group was normalized to the belly group. (B)

413 The protein levels of SFRP2 between the back and belly group. Each group had three

414 biological replicates. Error bars represent the mean ± S.D. of triplicate experiments. *,

415 P<0.05; **, P<0.01.

416

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417 Table 1. Primer sequences used in qRT-PCR for validation of differentially

418 expressed genes.

Gene Primers

GAPDH Forward primer: 5’TCACCATCTTCCAGGAGCGA3’

Reverse primer: 5’ CACAATGCCGAAGTGGTCGT3’

FRZB Forward primer: 5’CATCAAGTACCGCCACTCGT3’

Reverse primer:

5’GCCCCTCTACAGTTTCCATTGCT3’

SFRP2 Forward primer:

5’CCAGCCCGACTTCTCCTACAAGC3’Draft

Reverse primer: 5’TCCAGCACCTCTTTCATGGTCT3’

EN1 Forward primer: 5’CTCCTGGGGCTTATCCGTCC3’

Reverse primer: 5’CTCCCAGTTCCAGCCAAGGTC3’

CACNA1S Forward primer:

5’TCATCCTCAGCGAGATCGACAC3’

Reverse primer:

5’GATCAGCCTCATGACCCGGAAC3’

DUSP26 Forward primer: 5’TAACTGGCTCTGGGCATCCAT3’

Reverse primer: 5’CCGCTCCAGCTCGAAGACGTT3’

PTP4A3 Forward primer: 5’

AGAACATGCGCTTCCTCATCACC3’

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Reverse primer: 5’TGTCGTAGGTCACTTCGCACAC3’

HBB1 Forward primer: 5’GCTGCTGGTTGTCTACCCAT3’

Reverse primer: 5’AGCCAGCACCTTCTTGCCAT3’

MRPL36 Forward primer: 5’CCCGCGCTGGGCTTCAAGAC3’

Reverse primer: 5’

GGGTTGCTCTCGCAGTACACGAAC3’

419

420 Draft

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421 Table 2. Summary of RNA-seq data for each sample.

Sample ID Raw reads Quality trimmed Adaptor trimmed Clean reads Clean ratio rRNA ratio422

B1 62,459,166 59,686,034 58,308,948 54,544,462 87.30% 0.30% 423

B2 42,040,878 41,785,111 41,048,067 40,089,926 95.40% 0.70% 424 B3 57,515,444 56,961,934 56,014,421Draft 54,639,520 95.00% 0.20% F1 45,589,348 45,273,339 44,450,260 43,352,936 95.10% 2.60%425

F2 56,952,408 56,446,129 55,441,949 53,996,816 94.80% 0.90% 426

F3 49,299,600 48,995,596 48,156,222 47,052,794 95.40% 0.10% 427

428 Clean ratio= (Clean reads/Raw reads)×%

429

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430 Table 3. Mapping statistics for each sample.

Sample All reads Mapped Mapped Mapped broken Mapped unique Mapped multiple Mapping ratio

ID reads paired paired reads reads reads

reads B1 54,391,204 44,245,125 42,943,776 Draft1,301,349 39,786,635 4,458,490 81.30% B2 39,826,940 33,675,819 32,120,474 1,555,345 30,460,340 3,215,479 84.60%

B3 54,509,484 45,897,437 44,222,232 1,675,205 41,895,083 4,002,354 84.20%

F1 42,242,866 35,960,580 34,407,676 1,552,904 32,706,780 3,253,800 85.10%

F2 53,524,836 45,300,446 43,337,930 1,962,516 40,933,492 4,366,954 84.60%

F3 47,012,530 39,549,833 37,741,242 1,808,591 35,663,951 3,885,882 84.10%

431 Mapping ratio=Mapped reads/All read

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432 Supporting Information

433 Figure S1. Bar plot of GO enrichment results. GO functional enrichment analysis

434 of the differentially expressed genes, which were all considered statistically

435 significant.

436 Figure S2. Bar plot of KEGG enrichment results. KEGG pathway analysis of the

437 differentially expressed genes, which were all considered statistically significant.

438 Figure S3. Expressed genes annotated in the Wnt signaling pathway. The

439 expressed genes are in the red box.

440 Table S1. Gene expression in the two groups.

441 Table S2. Differentially expressedDraft genes in the two groups.

442 Table S3. Significant GO terms of the differentially expressed genes.

443 Table S4. Significant KEGG pathways of the differentially expressed genes.

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Draft

Figure 1. Mapped region distribution of each sample. Mapped read distribution for each sample, showing the percentage of reads that mapped to each type of genomic region (genes, coding regions, splice sequences, intron sequences, intergenic regions, and non-coding regions (5’UTR and 3’UTR)) in the Ensembl OryCun2.0 database.

78x53mm (300 x 300 DPI)

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Draft

Figure 2. Volcano plot of differentially expressed genes. Red dots show upregulated genes, green dots show downregulated genes, and two blue lines show a 2-fold change in expression (P=0.05).

190x189mm (300 x 300 DPI)

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Figure 3. GO enrichment of genes related to fur development. Within the molecular function category, we identified genes induced by fur development in rex rabbits. GO categories included biological processes, cellular component, and molecular function. Draft 219x112mm (300 x 300 DPI)

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Draft

Figure 4. Diagram of the interaction network. Thicker lines show stronger interactions of differentially expressed genes and their partner genes.

169x145mm (300 x 300 DPI)

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Draft

Figure 5. Analysis of differentially expressed genes involved in the regulation of fur development in rabbits. (A) The mRNA levels of FRZB, SFRP2, DUSP26, PTP4A3, EN1, CACNA1S, HBB1 and MRPL36 between back and belly groups. The expression level of genes in the back group was normalized to the belly group. (B) The protein levels of SFRP2 between the back and belly group. Each group had three biological replicates. Error bars represent the mean ± S.D. of triplicate experiments. *, P<0.05; **, P<0.01.

64x59mm (300 x 300 DPI)

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Draft

169x127mm (300 x 300 DPI)

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Draft

169x127mm (300 x 300 DPI)

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Draft

93x66mm (300 x 300 DPI)

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Supplemental Table S1. Gene expression in the two groups Gene_id gene_name Descriptionlocus Group B_FPKM Group F_FPKM ENSOCUG00000022631 ZNF536 zinc finger proteinGL018722:1186965-1457769 536 [Source:HGNC0.996739667 Symbol;Acc:HGNC:29025] 1.023735333 ENSOCUG00000016727 NELL2 NEL-like 2 8:1590416-1918522(chicken) [Source:HGNC0.990464667 Symbol;Acc:HGNC:7751] 1.031116333 ENSOCUG00000027292 IQCF1 IQ motif containing9:19061137-19062738 F1 [Source:HGNC0.997219 Symbol;Acc:HGNC:28607] 1.048545 ENSOCUG00000024960 - UncharacterizedX:78745887-78746484 protein [Source:UniProtKB/TrEMBL;Acc:G1TVP3]0.957098333 1.013687 ENSOCUG00000011337 AURKC aurora kinaseGL018763:289958-294009 C [Source:HGNC Symbol;Acc:HGNC:11391]0.997992 1.061457667 ENSOCUG00000026745 - Uncharacterized4:8993441-9005131 protein [Source:UniProtKB/TrEMBL;Acc:G1U289]0.947800667 1.010491 ENSOCUG00000026058 FTCD formimidoyltransferase14:163823184-163837483 cyclodeaminase0.983903333 [Source:HGNC Symbol;Acc:HGNC:3974] 1.053086 ENSOCUG00000009801 CHIC1 cysteine-richX:52166429-52242129 hydrophobic domain 10.928247 [Source:HGNC Symbol;Acc:HGNC:1934] 1.000059333 ENSOCUG00000029407 HMGA2 high mobility4:44715270-44850410 group AT-hook 2 [Source:HGNC0.930181 Symbol;Acc:HGNC:5009] 1.020447667 ENSOCUG00000004393 SYT15 Uncharacterized18:8796448-8807927 protein [Source:UniProtKB/TrEMBL;Acc:G1SLQ1]0.958430333 1.052739333 ENSOCUG00000013116 CDH24 cadherin 24,17:43272090-43279408 type 2 [Source:HGNC0.924978667 Symbol;Acc:HGNC:14265] 1.023153333 ENSOCUG00000025458 SMARCC1 GL018812:11062-142410.957120667 1.064048667 ENSOCUG00000014204 FUT4 fucosyltransferase1:122320979-122322352 4 (alpha (1,3)0.990621333 fucosyltransferase, myeloid-specific) 1.12166 [Source:HGNC Symbol;Acc:HGNC:4015] ENSOCUG00000004266 FAM222A family with GL019210:37990-81273sequence similarity0.968984333 222, member A [Source:HGNC 1.103016667 Symbol;Acc:HGNC:25915] ENSOCUG00000009414 C17orf64 chromosome19:26755020-26762862 17 open reading frame0.875599333 64 [Source:HGNC Symbol;Acc:HGNC:26990] 1.001547 ENSOCUG00000026685 - Uncharacterized17:40542364-40545127 protein [Source:UniProtKB/TrEMBL;Acc:G1TMV3]0.967109 1.106463 ENSOCUG00000017614 - UncharacterizedAAGW02079214:17-38973 protein [Source:UniProtKB/TrEMBL;Acc:G1TE23]0.886652667 1.022333667 ENSOCUG00000008688 WDR96 cilia and flagella18:52060848-52172272 associated protein0.896277333 43 [Source:HGNC 1.033549667Symbol;Acc:HGNC:26684] ENSOCUG00000026933 NPTXR neuronal pentraxin4:84388278-84425274 receptor [Source:HGNC0.960864 Symbol;Acc:HGNC:7954] 1.114302333 ENSOCUG00000009852 RSPH4A radial spoke12:105535951-105583776 head 4 homolog A (Chlamydomonas)0.96107 [Source:HGNC 1.122411333 Symbol;Acc:HGNC:21558] ENSOCUG00000000714 RARB retinoicDraft acid14:11676190-12163337 receptor, beta [Source:HGNC0.903852333 Symbol;Acc:HGNC:9865] 1.062696333 ENSOCUG00000024411 C7orf61 chromosome6:27327602-27332022 7 open reading frame0.969506667 61 [Source:HGNC 1.142842333Symbol;Acc:HGNC:22135] ENSOCUG00000027729 NAT8L N-acetyltransferaseGL018796:104227-106710 8-like (GCN5-related,0.951567 putative) [Source:HGNC 1.131805 Symbol;Acc:HGNC:26742] ENSOCUG00000010719 WDR76 Oryctolagus17:28398498-28521659 cuniculus WD repeat0.849363667 domain 76 (WDR76), 1.012293333 mRNA. [Source:RefSeq mRNA;Acc:NM_001171318] ENSOCUG00000020972 CYP2C14 cytochrome 18:42381501-42423096P450 2C14 [Source:RefSeq0.944429 peptide;Acc:NP_001164591] 1.12879 ENSOCUG00000021395 EFR3B EFR3 homolog2:174030295-174195087 B (S. cerevisiae)0.897589667 [Source:HGNC Symbol;Acc:HGNC:29155] 1.073314 ENSOCUG00000004927 BCAS1 breast carcinomaGL018712:2447106-2543044 amplified sequence0.932518667 1 [Source:HGNC Symbol;Acc:HGNC:974] 1.117866 ENSOCUG00000011843 HSD11B2 Oryctolagus5:23014000-23020581 cuniculus hydroxysteroid0.867844 (11-beta) dehydrogenase 1.043334 2 (HSD11B2), mRNA. [Source:RefSeq mRNA;Acc:NM_001082752] ENSOCUG00000014290 DUOXA2 dual oxidase17:27374401-27444343 maturation factor 2 [Source:HGNC0.890958 Symbol;Acc:HGNC:32698] 1.072581667 ENSOCUG00000022517 - UncharacterizedGL019254:48404-60035 protein [Source:UniProtKB/TrEMBL;Acc:G1TLG1]0.869515 1.065269333 ENSOCUG00000023847 CEP57L1 centrosomal12:97050057-97117140 protein 57kDa-like0.994793667 1 [Source:HGNC Symbol;Acc:HGNC:21561] 1.223215 ENSOCUG00000021957 GPR141 G protein-coupled10:21120738-21121656 receptor 1410.968751667 [Source:HGNC Symbol;Acc:HGNC:19997] 1.199024667 ENSOCUG00000011835 IL8 Oryctolagus15:76368975-76371927 cuniculus interleukin0.906659667 8 (IL8), mRNA. [Source:RefSeq 1.142488 mRNA;Acc:NM_001082293] ENSOCUG00000007260 - Uncharacterized12:30850977-30902483 protein [Source:UniProtKB/TrEMBL;Acc:G1SSP1]0.819123667 1.032323 ENSOCUG00000029474 - UncharacterizedGL018733:1348662-1355139 protein [Source:UniProtKB/TrEMBL;Acc:U3KM76]0.996402 1.256937 ENSOCUG00000024036 COL6A5 collagen, type14:963914-1100656 VI, alpha 5 [Source:HGNC0.844292333 Symbol;Acc:HGNC:26674] 1.071333333 ENSOCUG00000024132 - Uncharacterized12:141424551-141443559 protein [Source:UniProtKB/TrEMBL;Acc:G1TIJ8]0.824246667 1.046397 ENSOCUG00000000184 NCKAP5 NCK-associated7:69801660-69985238 protein 5 [Source:HGNC0.943987333 Symbol;Acc:HGNC:29847] 1.203175 ENSOCUG00000010247 ATP6V0D2 ATPase, H+3:101581451-101636320 transporting, lysosomal0.873308 38kDa, V0 subunit 1.113754333 d2 [Source:HGNC Symbol;Acc:HGNC:18266] ENSOCUG00000016641 GPR97 G protein-coupled5:13738039-13761892 receptor 97 [Source:HGNC0.938584667 Symbol;Acc:HGNC:13728] 1.204249333 ENSOCUG00000001103 CASP1 caspase 1, apoptosis-related1:111573021-111585250 cysteine0.915474333 peptidase [Source:HGNC 1.177220333 Symbol;Acc:HGNC:1499] ENSOCUG00000009903 TSPYL5 TSPY-like 53:113152501-113153752 [Source:HGNC Symbol;Acc:HGNC:29367]0.932270333 1.203201333 ENSOCUG00000017597 GRM2 glutamate receptor,9:18908130-18916300 metabotropic0.945418333 2 [Source:HGNC Symbol;Acc:HGNC:4594] 1.221070667 ENSOCUG00000006811 NLGN3 neuroligin 3X:49615537-49635927 [Source:HGNC Symbol;Acc:HGNC:14289]0.814141 1.057413333 ENSOCUG00000022089 - 14:108525100-1085258810.997062 1.295206667 ENSOCUG00000005126 RHOH ras homolog2:29498138-29498714 family member H 0.972153667[Source:HGNC Symbol;Acc:HGNC:686] 1.270073667 ENSOCUG00000012342 CDC25A cell division9:15983263-16002402 cycle 25A [Source:HGNC0.775478 Symbol;Acc:HGNC:1725] 1.019443667 ENSOCUG00000005537 RSPH9 radial spoke12:33079253-33095700 head 9 homolog (Chlamydomonas)0.827265333 [Source:HGNC 1.093829333 Symbol;Acc:HGNC:21057]

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ENSOCUG00000029142 - UncharacterizedGL019297:77710-84007 protein [Source:UniProtKB/TrEMBL;Acc:U3KMC9]0.788135333 1.056076333 ENSOCUG00000003039 TTPA tocopherol (alpha)3:78846210-78868407 transfer protein0.751806667 [Source:HGNC Symbol;Acc:HGNC:12404] 1.016696 ENSOCUG00000010823 PFAS phosphoribosylformylglycinamidine19:10996821-110224330.875111 synthase [Source:HGNC 1.191824 Symbol;Acc:HGNC:8863] ENSOCUG00000012589 SMPDL3B sphingomyelin13:137537364-137554539 phosphodiesterase,0.846829333 acid-like 3B [Source:HGNC 1.154351333 Symbol;Acc:HGNC:21416] ENSOCUG00000016476 IL18R1 Oryctolagus2:90028850-90075994 cuniculus interleukin0.918324667 18 receptor 1 (IL18R1), mRNA. 1.25298 [Source:RefSeq mRNA;Acc:NM_001164863] ENSOCUG00000004096 - UncharacterizedGL018981:115216-188109 protein [Source:UniProtKB/TrEMBL;Acc:G1SL19]0.961117667 1.325837 ENSOCUG00000016904 PLXNC1 plexin C1 [Source:HGNC4:73487921-73643714 Symbol;Acc:HGNC:9106]0.796695667 1.101224 ENSOCUG00000016711 KIAA1958 KIAA1958 [Source:HGNC1:673403-765025 Symbol;Acc:HGNC:23427]0.732293667 1.021946 ENSOCUG00000005141 CHST11 carbohydrate4:83551753-83794668 (chondroitin 4) sulfotransferase0.790493 11 [Source:HGNC 1.105705333 Symbol;Acc:HGNC:17422] ENSOCUG00000007927 SKA1 spindle and 9:91095294-91115561kinetochore associated 0.821681complex subunit 1 1.155120667[Source:HGNC Symbol;Acc:HGNC:28109] ENSOCUG00000001278 INTU inturned planar15:103461144-103551539 cell polarity protein0.890661667 [Source:HGNC Symbol;Acc:HGNC:29239] 1.26131 ENSOCUG00000011911 SLC47A2 solute carrierGL018817:105011-124361 family 47 (multidrug 0.983549and toxin extrusion), 1.395183333 member 2 [Source:HGNC Symbol;Acc:HGNC:26439] ENSOCUG00000021441 NKG7 natural killerGL019218:83950-85794 cell granule protein0.949191933 7 [Source:HGNC Symbol;Acc:HGNC:7830] 1.351603333 ENSOCUG00000003060 GCH1 GTP cyclohydrolase17:73547366-73601910 1 [Source:HGNC0.942627667 Symbol;Acc:HGNC:4193] 1.363585 ENSOCUG00000012911 CD4 Oryctolagus8:32816216-32841362 cuniculus CD4 molecule0.821646167 (CD4), mRNA. [Source:RefSeq 1.188965 mRNA;Acc:NM_001082313] ENSOCUG00000017568 P2RY6 pyrimidinergic1:143186781-143187795 receptor P2Y, G-protein0.896901333 coupled, 6 [Source:HGNC 1.303623333 Symbol;Acc:HGNC:8543] ENSOCUG00000005480 TAF4B TAF4b RNA9:67462831-67598517 polymerase II, TATA0.817886667 box binding protein 1.190033333 (TBP)-associated factor, 105kDa [Source:HGNC Symbol;Acc:HGNC:11538] ENSOCUG00000010671 SH2D2A SH2 domain13:36145338-36153821 containing 2A [Source:HGNC0.913819333 Symbol;Acc:HGNC:10821] 1.331801267 ENSOCUG00000012227 CD226 CD226 molecule9:110000418-110100277 [Source:HGNC0.946290667 Symbol;Acc:HGNC:16961] 1.379721 ENSOCUG00000006864 - UncharacterizedGL018823:48099-53652 protein [Source:UniProtKB/TrEMBL;Acc:G1SRV6]0.89239 1.308917667 ENSOCUG00000027632 - UncharacterizedX:109375102-109375621 protein [Source:UniProtKB/TrEMBL;Acc:G1U3N4]0.781524667 1.152628667 ENSOCUG00000021757 SNX22 sorting nexin17:8090022-8092037 22 [Source:HGNC0.795779333 Symbol;Acc:HGNC:16315] 1.181112333 ENSOCUG00000029436 - UncharacterizedDraft2:98623374-98623951 protein [Source:UniProtKB/TrEMBL;Acc:G1TUA6]0.809129333 1.202876667 ENSOCUG00000021915 PLD6 phospholipaseGL018920:159683-159938 D family, member 6 [Source:HGNC0.88066 Symbol;Acc:HGNC:30447] 1.311156667 ENSOCUG00000017387 CLSPN claspin [Source:HGNCGL018704:2562967-2601221 Symbol;Acc:HGNC:19715]0.790943333 1.184944 ENSOCUG00000005666 DHRS9 dehydrogenase/reductase7:108826925-108853244 (SDR0.933061333 family) member 9 [Source:HGNC 1.403514667 Symbol;Acc:HGNC:16888] ENSOCUG00000017194 - Uncharacterized18:69736477-69741771 protein [Source:UniProtKB/TrEMBL;Acc:G1TD70]0.735858333 1.111137333 ENSOCUG00000016478 RAD54B RAD54 homolog3:110005881-110095050 B (S. cerevisiae)0.861068667 [Source:HGNC Symbol;Acc:HGNC:17228] 1.302413333 ENSOCUG00000025918 HIST2H2AA4histone cluster13:42158888-42159281 2, H2ac [Source:HGNC1.995073333 Symbol;Acc:HGNC:4738] 3.021513333 ENSOCUG00000001150 GIMAP8 GTPase, IMAPGL018806:414269-434231 family member 8 [Source:HGNC0.85779 Symbol;Acc:HGNC:21792] 1.304510333 ENSOCUG00000011798 KL klotho [Source:HGNCGL018702:3757627-3823681 Symbol;Acc:HGNC:6344]0.734362 1.122955667 ENSOCUG00000026204 TIFAB TRAF-interacting3:18075621-18076104 protein with forkhead-associated0.723977 domain, 1.11653 family member B [Source:HGNC Symbol;Acc:HGNC:34024] ENSOCUG00000025147 - Uncharacterized5:22550888-22559208 protein [Source:UniProtKB/TrEMBL;Acc:G1SJQ8]0.800703333 1.239217 ENSOCUG00000015121 - 7:16235652-166486700.955665333 1.47956 ENSOCUG00000000814 - 11:18172244-181730380.876733667 1.357444667 ENSOCUG00000002818 FAM64A family with 19:13665870-13669151sequence similarity0.925319667 64, member A [Source:HGNC 1.449379 Symbol;Acc:HGNC:25483] ENSOCUG00000003854 TPMT OryctolagusGL018711:1963499-1980034 cuniculus thiopurine S-methyltransferase0.940892 1.490363333(TPMT), mRNA. [Source:RefSeq mRNA;Acc:NM_001082684] ENSOCUG00000027017 PARVG parvin, gammaGL019802:10721-26265 [Source:HGNC 0.845958333Symbol;Acc:HGNC:14654] 1.344465333 ENSOCUG00000010254 - Uncharacterized9:50740448-51088848 protein [Source:UniProtKB/TrEMBL;Acc:G1SYX9]0.889781333 1.41457 ENSOCUG00000023856 - UncharacterizedGL018806:230418-238581 protein [Source:UniProtKB/TrEMBL;Acc:G1TPG2]1.998684667 3.19599 ENSOCUG00000001961 RAD51AP1 RAD51 associated8:30635518-30650301 protein 1 [Source:HGNC0.946447667 Symbol;Acc:HGNC:16956] 1.514251667 ENSOCUG00000014423 IKZF1 IKAROS familyGL018745:1730412-1853435 zinc finger 1 (Ikaros)0.937168667 [Source:HGNC 1.502113667Symbol;Acc:HGNC:13176] ENSOCUG00000002703 FOXM1 forkhead box8:29085636-29096751 M1 [Source:HGNC Symbol;Acc:HGNC:3818]1.88338 3.02239 ENSOCUG00000018028 7SK 7SK RNA [Source:RFAM;Acc:RF00100]3:147413978-1474143260.797222333 1.282107 ENSOCUG00000010608 TFF1 trefoil factorAAGW02082501:2907-5853 1 [Source:HGNC Symbol;Acc:HGNC:11755]0.974026667 1.57875 ENSOCUG00000017214 RIC3 RIC3 acetylcholine1:149881738-149964538 receptor chaperone0.782333667 [Source:HGNC 1.270771333 Symbol;Acc:HGNC:30338] ENSOCUG00000015423 ZDHHC23 zinc finger, 14:105264561-105275623DHHC-type containing0.818654333 23 [Source:HGNC Symbol;Acc:HGNC:28654] 1.343337 ENSOCUG00000014702 ECE2 endothelin converting14:81376926-81536581 enzyme 20.767028333 [Source:HGNC Symbol;Acc:HGNC:13275] 1.259272 ENSOCUG00000002953 CIDEB cell death-inducing17:44349203-44351318 DFFA-like 1.910874333effector b [Source:HGNC 3.153893333 Symbol;Acc:HGNC:1977] ENSOCUG00000026073 FANCA Fanconi anemia,GL018965:31207-74144 complementation0.819283667 group A [Source:HGNC 1.360099333 Symbol;Acc:HGNC:3582]

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ENSOCUG00000024620 - UncharacterizedGL018888:421197-422163 protein [Source:UniProtKB/TrEMBL;Acc:G1TMB2]0.946872333 1.57626 ENSOCUG00000022346 CD5 OryctolagusGL018717:3960166-3984972 cuniculus CD5 molecule0.751347667 (CD5), mRNA. [Source:RefSeq 1.256100333 mRNA;Acc:NM_001082177] ENSOCUG00000026826 CLDN19 claudin 19 [Source:HGNC13:123991174-123999188 Symbol;Acc:HGNC:2040]0.795301 1.331820333 ENSOCUG00000004047 SKA3 spindle and 8:43462503-43478504kinetochore associated0.842874333 complex subunit 3 1.415257667[Source:HGNC Symbol;Acc:HGNC:20262] ENSOCUG00000001241 MFSD4 major facilitator16:66563215-66584843 superfamily domain0.910825667 containing 4 [Source:HGNC 1.536063333 Symbol;Acc:HGNC:25433] ENSOCUG00000007701 KANK4 KN motif and13:104258519-104286788 ankyrin repeat domains0.978564 4 [Source:HGNC 1.655673333 Symbol;Acc:HGNC:27263] ENSOCUG00000005587 PPP1R14D protein phosphatase17:31239684-31252760 1, regulatory0.676969333 (inhibitor) subunit 14D [Source:HGNC 1.14546 Symbol;Acc:HGNC:14953] ENSOCUG00000004490 GUCY1A2 guanylate cyclase1:109604152-109941502 1, soluble, alpha 0.9578882 [Source:HGNC Symbol;Acc:HGNC:4684] 1.621616667 ENSOCUG00000029646 - Uncharacterized15:50473573-50550816 protein [Source:UniProtKB/TrEMBL;Acc:U3KNT2]1.888431667 3.197566667 ENSOCUG00000027626 CD247 Oryctolagus13:25457776-25540068 cuniculus CD247 molecule0.765721333 (CD247), mRNA. 1.302995667 [Source:RefSeq mRNA;Acc:NM_001082002] ENSOCUG00000010249 UBE2T ubiquitin-conjugating16:69339635-69347664 enzyme E2T (putative)1.91891 [Source:HGNC 3.278626667 Symbol;Acc:HGNC:25009] ENSOCUG00000007559 TRPV5 Oryctolagus7:9203870-9230082 cuniculus transient0.663733667 receptor potential cation 1.136422333 channel, subfamily V, member 5 (TRPV5), mRNA. [Source:RefSeq mRNA;Acc:NM_001082657] ENSOCUG00000003707 DLX1 distal-less homeobox7:111818347-111826388 1 [Source:HGNC0.723108 Symbol;Acc:HGNC:2914] 1.246341 ENSOCUG00000001826 - UncharacterizedX:78240487-78347560 protein [Source:UniProtKB/TrEMBL;Acc:G1SG76]1.914093333 3.301093333 ENSOCUG00000013586 STIL SCL/TAL1 13:119314680-119379675interrupting locus [Source:HGNC0.65507 Symbol;Acc:HGNC:10879] 1.134847667 ENSOCUG00000009512 PLA1A phospholipase14:99141383-99173780 A1 member A [Source:HGNC0.925354667 Symbol;Acc:HGNC:17661] 1.60829 ENSOCUG00000027340 DTX1 deltex 1, E321:8791702-8818887 ubiquitin ligase [Source:HGNC0.695185667 Symbol;Acc:HGNC:3060] 1.212846667 ENSOCUG00000027908 SKIDA1 SKI/DACH 16:39696519-39698346domain containing 0.7171883331 [Source:HGNC Symbol;Acc:HGNC:32697] 1.252806333 ENSOCUG00000010701 HEMGN hemogen [Source:HGNC1:15127461-15147604 Symbol;Acc:HGNC:17509]0.625745667 1.098020667 ENSOCUG00000027725 - GL018986:265109-2656270.659656333 1.179256 ENSOCUG00000027803 SH3GL3 SH3-domainGL018737:18476-75750 GRB2-like 3 [Source:HGNC0.761494667 Symbol;Acc:HGNC:10832] 1.364984333 ENSOCUG00000008068 BCHE butyrylcholinesterase14:60405507-60483174 [Source:HGNC0.825007667 Symbol;Acc:HGNC:983] 1.49073 ENSOCUG00000028021 PRIMA1 prolineDraft rich 20:12447967-12493511membrane anchor 10.963417667 [Source:HGNC Symbol;Acc:HGNC:18319] 1.741577333 ENSOCUG00000025201 - UncharacterizedGL018781:813960-824294 protein [Source:UniProtKB/TrEMBL;Acc:G1TRD4]0.623264667 1.128159333 ENSOCUG00000000360 CDH6 cadherin 6, type11:53084183-53222984 2, K-cadherin (fetal1.929906667 kidney) [Source:HGNC 3.508823333 Symbol;Acc:HGNC:1765] ENSOCUG00000012683 ADAM33 ADAM metallopeptidase4:10550400-10560369 domain 331.80474 [Source:HGNC Symbol;Acc:HGNC:15478] 3.28882 ENSOCUG00000013264 - Uncharacterized1:50012144-50034134 protein [Source:UniProtKB/TrEMBL;Acc:G1T525]0.616182333 1.123139667 ENSOCUG00000012907 TBX21 T-box 21 [Source:HGNC19:39559624-39570319 Symbol;Acc:HGNC:11599]0.870307 1.589593 ENSOCUG00000025273 - Uncharacterized5:22456729-22462013 protein [Source:UniProtKB/TrEMBL;Acc:G1T7P3]0.681738 1.245309667 ENSOCUG00000006283 HAVCR2 hepatitis A virus3:38565753-38589132 cellular receptor 20.724179 [Source:HGNC Symbol;Acc:HGNC:18437] 1.324900333 ENSOCUG00000015626 NGEF neuronal guanineGL018736:450132-489775 nucleotide exchange1.683613333 factor [Source:HGNC 3.084123333 Symbol;Acc:HGNC:7807] ENSOCUG00000004499 SLC4A1 solute carrier19:44558620-44573177 family 4 (anion exchanger),0.631047667 member 1 (Diego 1.157443333 blood group) [Source:HGNC Symbol;Acc:HGNC:11027] ENSOCUG00000025914 - UncharacterizedGL018758:1143068-1143650 protein [Source:UniProtKB/TrEMBL;Acc:G1TX38]0.603481 1.108976333 ENSOCUG00000024419 - UncharacterizedGL018760:68081-77682 protein [Source:UniProtKB/TrEMBL;Acc:G1TM85]1.989326667 3.656466667 ENSOCUG00000022161 SARDH sarcosine dehydrogenaseGL019710:568-14700 [Source:HGNC0.734066667 Symbol;Acc:HGNC:10536] 1.349451667 ENSOCUG00000006970 SLC44A4 solute carrier12:20713896-20727833 family 44, member 4 0.683752[Source:HGNC Symbol;Acc:HGNC:13941] 1.262846333 ENSOCUG00000018769 U3 Small nucleolar19:29323714-29763354 RNA U3 [Source:RFAM;Acc:RF00012]0.705956667 1.318503333 ENSOCUG00000001813 ARG1 Arginase-1 12:121799078-121865303[Source:UniProtKB/Swiss-Prot;Acc:Q95KM0]0.777843333 1.458750333 ENSOCUG00000014135 SUCNR1 succinate receptor14:45995575-46009066 1 [Source:HGNC0.838891 Symbol;Acc:HGNC:4542] 1.579467 ENSOCUG00000012133 - UncharacterizedAAGW02081976:4112-14246 protein [Source:UniProtKB/TrEMBL;Acc:G1T2N9]0.641683 1.221364 ENSOCUG00000011604 ESM1 endothelial cell-specific11:70957114-70966487 molecule 10.563956 [Source:HGNC Symbol;Acc:HGNC:3466] 1.076042667 ENSOCUG00000017822 SSC5D GL019887:13750-204871.553153333 3.009753333 ENSOCUG00000007493 - UncharacterizedGL018707:279294-281968 protein [Source:UniProtKB/TrEMBL;Acc:G1ST63]0.518416333 1.006032 ENSOCUG00000015578 - X:50078085-500791980.603243333 1.170802333 ENSOCUG00000009734 ALX3 ALX homeobox13:54096114-54106540 3 [Source:HGNC Symbol;Acc:HGNC:449]0.950042 1.855696667 ENSOCUG00000008274 PROX1 prospero homeobox16:59173366-59199534 1 [Source:HGNC1.678253333 Symbol;Acc:HGNC:9459] 3.290476667 ENSOCUG00000011371 GPR17 G protein-coupled7:59374854-59401581 receptor 17 [Source:HGNC0.721820667 Symbol;Acc:HGNC:4471] 1.421425 ENSOCUG00000006154 GINS4 GINS complexGL018706:1596631-1606575 subunit 4 (Sld5 0.702296667homolog) [Source:HGNC 1.388320667 Symbol;Acc:HGNC:28226] ENSOCUG00000029219 DHH desert hedgehog4:33388112-33390690 [Source:HGNC0.637350333 Symbol;Acc:HGNC:2865] 1.266614333 ENSOCUG00000024629 RASAL3 RAS proteinGL018829:490574-500257 activator like 3 [Source:HGNC0.841543667 Symbol;Acc:HGNC:26129] 1.678566667

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ENSOCUG00000002433 FBXO41 F-box protein2:113137598-113146559 41 [Source:HGNC0.925904667 Symbol;Acc:HGNC:29409] 1.849834 ENSOCUG00000029274 KLRD1 killer cell lectin-like8:28570335-28575750 receptor subfamily0.535946333 D, member 1 [Source:HGNC 1.076417667 Symbol;Acc:HGNC:6378] ENSOCUG00000023873 NT5M 5',3'-nucleotidase,GL018920:183281-232266 mitochondrial0.921070333 [Source:HGNC Symbol;Acc:HGNC:15769] 1.856960667 ENSOCUG00000019713 7SK 7SK RNA [Source:RFAM;Acc:RF00100]15:68716393-688741710.538436667 1.085546667 ENSOCUG00000014085 CREG2 cellular repressor2:91012342-91041365 of E1A-stimulated0.804755 genes 2 [Source:HGNC 1.622756667 Symbol;Acc:HGNC:14272] ENSOCUG00000026452 - GL018747:380902-3812140.8363 1.68666 ENSOCUG00000002587 TSHZ2 teashirt zincGL018712:2899691-3123375 finger homeobox 2 [Source:HGNC1.67897 Symbol;Acc:HGNC:13010] 3.42523 ENSOCUG00000010181 ARHGEF39 Rho guanine1:18263740-18266546 nucleotide exchange0.724022333 factor (GEF) 39 [Source:HGNC 1.493150667 Symbol;Acc:HGNC:25909] ENSOCUG00000024754 GNAT3 guanine nucleotide7:35479467-35534768 binding protein,0.966445667 alpha transducing 2.0079656673 [Source:HGNC Symbol;Acc:HGNC:22800] ENSOCUG00000016067 - protein disulfideAAGW02082232:7-536 isomerase family0.597756667 A, member 2 [Source:HGNC 1.242733333 Symbol;Acc:HGNC:14180] ENSOCUG00000023339 SMCO3 single-pass membrane8:24791874-24800890 protein with0.604865667 coiled-coil domains 3 [Source:HGNC 1.261352 Symbol;Acc:HGNC:34401] ENSOCUG00000001856 CTSE Oryctolagus16:66243433-66257825 cuniculus cathepsin1.823376667 E (CTSE), mRNA. [Source:RefSeq 3.810233333 mRNA;Acc:NM_001082244] ENSOCUG00000024499 - Uncharacterized5:22371610-22377139 protein [Source:UniProtKB/TrEMBL;Acc:G1T7Q5]0.926768333 1.937256667 ENSOCUG00000021283 TCFL5 transcriptionGL019426:89-19816 factor-like 5 (basic1.440208667 helix-loop-helix) [Source:HGNC 3.013743333 Symbol;Acc:HGNC:11646] ENSOCUG00000023068 - Uncharacterized13:38770561-38770756 protein [Source:UniProtKB/TrEMBL;Acc:G1TUX0]1.572746667 3.308873333 ENSOCUG00000015887 WSCD2 WSC domainGL018777:642971-697869 containing 2 [Source:HGNC1.735885333 Symbol;Acc:HGNC:29117] 3.65613 ENSOCUG00000024631 - UncharacterizedGL019405:2219-5606 protein [Source:UniProtKB/TrEMBL;Acc:G1U7A3]0.626704 1.322647 ENSOCUG00000027828 SNORA23 Small nucleolar1:151224916-151289591 RNA SNORA23 [Source:RFAM;Acc:RF00319]3.8138 8.055876667 ENSOCUG00000026226 - Histone H2A12:10838764-10839157 [Source:UniProtKB/TrEMBL;Acc:G1U2Q4]1.59725 3.3821 ENSOCUG00000025025 AADACL3 arylacetamideGL018739:1464567-1471284 deacetylase-like 3 [Source:HGNC0.746197 Symbol;Acc:HGNC:32037] 1.588669667 ENSOCUG00000029126 - Uncharacterized17:44578026-44581291 protein [Source:UniProtKB/TrEMBL;Acc:G1T4V3]1.44101 3.068400667 ENSOCUG00000005408 - UncharacterizedGL018792:19389-35794 protein [Source:UniProtKB/TrEMBL;Acc:G1SNV3]0.968348 2.064088 ENSOCUG00000028219 FASLG Fas ligandDraft (TNF13:272822-279450 superfamily, member0.478263333 6) [Source:HGNC Symbol;Acc:HGNC:11936] 1.032536 ENSOCUG00000006050 SGOL1 shugoshin-like14:6259391-6274810 1 (S. pombe) [Source:HGNC0.939288667 Symbol;Acc:HGNC:25088] 2.039056667 ENSOCUG00000007602 HS3ST1 heparan sulfate2:1876129-1877065 (glucosamine) 3-O-sulfotransferase4.980853333 1 [Source:HGNC 10.81929333 Symbol;Acc:HGNC:5194] ENSOCUG00000028438 7SK 7SK RNA [Source:RFAM;Acc:RF00100]GL019070:140677-1854960.85164 1.85487 ENSOCUG00000005178 - Uncharacterized14:160101595-160101832 protein [Source:UniProtKB/TrEMBL;Acc:G1SNC9]3.685403333 8.053566667 ENSOCUG00000026584 - GL018886:398517-3992220.888253667 1.961163333 ENSOCUG00000003735 HCAR1 hydroxycarboxylicGL018824:92941-93847 acid receptor0.614571333 1 [Source:HGNC Symbol;Acc:HGNC:4532] 1.372053 ENSOCUG00000004080 RASL10B RAS-like, family19:24793340-24798868 10, member B [Source:HGNC0.746795 Symbol;Acc:HGNC:30295] 1.713354333 ENSOCUG00000023446 BIK BCL2-interactingGL019017:16561-28869 killer (apoptosis-inducing)1.320933333 [Source:HGNC 3.040476667 Symbol;Acc:HGNC:1051] ENSOCUG00000009271 HTR1B Oryctolagus12:64277945-64279115 cuniculus 5-hydroxytryptamine0.510793 (serotonin) 1.176407333 receptor 1B (HTR1B), mRNA. [Source:RefSeq mRNA;Acc:NM_001082790] ENSOCUG00000027635 GCG Glucagon [Source:UniProtKB/Swiss-Prot;Acc:P68274]7:101277070-1012879860.922597333 2.12677 ENSOCUG00000005876 ZNF775 zinc finger proteinGL018806:663801-676504 775 [Source:HGNC0.510061 Symbol;Acc:HGNC:28501] 1.181373333 ENSOCUG00000013536 NTRK3 neurotrophicGL018934:326285-412922 tyrosine kinase, receptor,0.647137667 type 3 [Source:HGNC 1.506474 Symbol;Acc:HGNC:8033] ENSOCUG00000021112 RAB39A RAB39A, member1:108623930-108665131 RAS oncogene0.689555333 family [Source:HGNC 1.612065Symbol;Acc:HGNC:16521] ENSOCUG00000009384 CD8B CD8b molecule2:99543302-99558388 [Source:HGNC0.865408333 Symbol;Acc:HGNC:1707] 2.03609 ENSOCUG00000010651 TEX101 testis expressedGL019267:95488-97898 101 [Source:HGNC0.501935667 Symbol;Acc:HGNC:30722] 1.184960333 ENSOCUG00000000476 FGF2 fibroblast growth15:98654461-98795608 factor 2 (basic)1.335057667 [Source:HGNC Symbol;Acc:HGNC:3676] 3.177233333 ENSOCUG00000005012 SH2D1A SH2 domainX:98832104-98855952 containing 1A [Source:HGNC0.684652667 Symbol;Acc:HGNC:10820] 1.630928667 ENSOCUG00000017860 GOLGA7B golgin A7 family,18:46001366-46008602 member B [Source:HGNC12.5513 Symbol;Acc:HGNC:31668] 30.0356 ENSOCUG00000014458 - Histone H2A12:10866848-10867241 [Source:UniProtKB/TrEMBL;Acc:G1U2Q4]1.75342 4.23365 ENSOCUG00000007576 FGF16 fibroblast growthX:69317973-69327921 factor 16 [Source:HGNC0.545968 Symbol;Acc:HGNC:3672] 1.322293333 ENSOCUG00000021032 - T cell receptorGL018758:1486338-1487245 beta variable 12-5 [Source:HGNC0.508373 Symbol;Acc:HGNC:12187] 1.233231 ENSOCUG00000005039 CA1 carbonic anhydrase3:100977974-100991288 I [Source:HGNC1.669944667 Symbol;Acc:HGNC:1368] 4.052078667 ENSOCUG00000022954 NFE2 nuclear factor,4:38046520-38048727 erythroid 2 [Source:HGNC1.65162 Symbol;Acc:HGNC:7780] 4.026096667 ENSOCUG00000029339 AWAT2 acyl-CoA waxX:48592013-48604333 alcohol acyltransferase0.483232667 2 [Source:HGNC 1.181483333 Symbol;Acc:HGNC:23251] ENSOCUG00000014146 - UncharacterizedGL019021:105145-105631 protein [Source:UniProtKB/TrEMBL;Acc:G1T6T3]4.65289 11.41576667 ENSOCUG00000012279 C14orf37 chromosome17:76460780-76472431 14 open reading frame0.701853333 37 [Source:HGNC 1.728567333 Symbol;Acc:HGNC:19846] ENSOCUG00000026750 RPL35A Uncharacterized3:131059267-131273579 protein [Source:UniProtKB/TrEMBL;Acc:G1U951]0.506037333 1.249713333

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ENSOCUG00000025343 - Uncharacterized7:4049935-4050061 protein [Source:UniProtKB/TrEMBL;Acc:G1TY87]26.6003 65.79433333 ENSOCUG00000006500 SLC4A4 Oryctolagus15:78490759-78813567 cuniculus solute carrier1.593633333 family 4, sodium bicarbonate 3.95266 cotransporter, member 4 (SLC4A4), mRNA. [Source:RefSeq mRNA;Acc:NM_001082060] ENSOCUG00000026714 CD5L CD5 molecule-like13:35407392-35416093 [Source:HGNC10.11470333 Symbol;Acc:HGNC:1690] 25.11476667 ENSOCUG00000003837 - Uncharacterized2:98664529-98889753 protein [Source:UniProtKB/TrEMBL;Acc:G1SKI5]0.448673333 1.11452 ENSOCUG00000004369 C5orf46 chromosome3:29847859-29858470 5 open reading frame 464.0662 [Source:HGNC 10.15034667Symbol;Acc:HGNC:33768] ENSOCUG00000023770 ABHD15 abhydrolase19:18630250-18635296 domain containing 15 [Source:HGNC0.68016 Symbol;Acc:HGNC:26971] 1.702713333 ENSOCUG00000005930 ZFPM2 zinc finger protein,3:120680891-121182761 FOG family0.595073333 member 2 [Source:HGNC 1.494253 Symbol;Acc:HGNC:16700] ENSOCUG00000000017 LIPE lipase, hormone-sensitiveGL018789:275657-295895 [Source:HGNC3.935206667 Symbol;Acc:HGNC:6621] 9.926643333 ENSOCUG00000027079 ASF1B anti-silencingGL019579:26886-28778 function 1B histone0.957143333 chaperone [Source:HGNC 2.424546667 Symbol;Acc:HGNC:20996] ENSOCUG00000027509 CX3CR1 Oryctolagus9:4397515-4413430 cuniculus chemokine0.579353333 (C-X3-C motif) receptor 1.471875333 1 (CX3CR1), mRNA. [Source:RefSeq mRNA;Acc:NM_001082134] ENSOCUG00000029078 - Uncharacterized13:39597641-39758611 protein [Source:UniProtKB/TrEMBL;Acc:G1U9M9]0.87646 2.237426667 ENSOCUG00000028103 - UncharacterizedX:72961767-72963106 protein [Source:UniProtKB/TrEMBL;Acc:G1TUX9]0.662356667 1.7167 ENSOCUG00000029439 HOXA10 homeobox A1010:11890292-11892754 [Source:HGNC Symbol;Acc:HGNC:5100]1.580596 4.102266667 ENSOCUG00000026199 KLRK1 Uncharacterized8:28488357-28495754 protein [Source:UniProtKB/TrEMBL;Acc:G1TGM3]0.642763333 1.677726667 ENSOCUG00000029129 GPR37L1 G protein-coupled16:69527898-69531018 receptor 37 like1.332886667 1 [Source:HGNC Symbol;Acc:HGNC:14923] 3.50723 ENSOCUG00000026247 - Uncharacterized3:74042336-74064023 protein [Source:UniProtKB/TrEMBL;Acc:G1U2M7]0.462810333 1.229020333 ENSOCUG00000005775 MYBL2 v-myb avianGL018718:3033680-3064828 myeloblastosis viral0.477168667 oncogene homolog-like 1.268985667 2 [Source:HGNC Symbol;Acc:HGNC:7548] ENSOCUG00000023030 RPL32 Uncharacterized6:10158286-10158694 protein [Source:UniProtKB/TrEMBL;Acc:G1TPH1]3.55528 9.456573333 ENSOCUG00000014031 TGM6 transglutaminase4:9531654-9553008 6 [Source:HGNC2.804306667 Symbol;Acc:HGNC:16255] 7.488303333 ENSOCUG00000004932 E2F7 E2F transcription4:56157772-56197784 factor 7 [Source:HGNC0.686045333 Symbol;Acc:HGNC:23820] 1.832025 ENSOCUG00000015801 ATP13A4 ATPase type14:89279681-89426464 13A4 [Source:HGNC0.568859 Symbol;Acc:HGNC:25422] 1.519556667 ENSOCUG00000029697 - Uncharacterized17:44600201-44603499 protein [Source:UniProtKB/TrEMBL;Acc:G1SGP8]0.627984 1.685164 ENSOCUG00000011077 ITI-HC3 OryctolagusDraft9:19828564-19841121 cuniculus inter-alpha-trypsin0.474549333 inhibitor heavy 1.277461667 chain3 (ITI-HC3), mRNA. [Source:RefSeq mRNA;Acc:NM_001082008] ENSOCUG00000024403 - UncharacterizedGL019650:119-494 protein [Source:UniProtKB/TrEMBL;Acc:G1TFP8]0.611833333 1.65806 ENSOCUG00000002916 TRAT1 T cell receptor14:110666120-110690518 associated transmembrane0.578092333 adaptor 1 [Source:HGNC 1.585127 Symbol;Acc:HGNC:30698] ENSOCUG00000028085 - Uncharacterized13:71092120-71092426 protein [Source:UniProtKB/TrEMBL;Acc:G1SD95]0.428263333 1.183283667 ENSOCUG00000014900 C4orf36 chromosome15:66629153-66634964 4 open reading frame 1.97562436 [Source:HGNC Symbol;Acc:HGNC:28386] 5.48325 ENSOCUG00000017622 NOVA1 neuro-oncological17:46515045-46666266 ventral antigen4.444203333 1 [Source:HGNC Symbol;Acc:HGNC:7886] 12.3745 ENSOCUG00000004914 RAB36 RAB36, memberGL018810:183801-199539 RAS oncogene0.691740667 family [Source:HGNC 1.935276667 Symbol;Acc:HGNC:9775] ENSOCUG00000022000 - UncharacterizedGL019052:177426-233725 protein [Source:UniProtKB/TrEMBL;Acc:G1U4A4]0.72358 2.062052 ENSOCUG00000025019 - Uncharacterized2:98664529-98889753 protein [Source:UniProtKB/TrEMBL;Acc:G1SQJ9]0.353196667 1.0152 ENSOCUG00000009838 FIGN fidgetin [Source:HGNC7:102882978-103009799 Symbol;Acc:HGNC:13285]1.149461 3.315996667 ENSOCUG00000000575 HAVCR1 hepatitis A virus3:38519798-38546290 cellular receptor2.384353333 1 [Source:HGNC Symbol;Acc:HGNC:17866] 6.937033333 ENSOCUG00000027526 - Uncharacterized4:26240443-26240737 protein [Source:UniProtKB/TrEMBL;Acc:G1U3V2]3.33951 9.81301 ENSOCUG00000028229 - GL019052:177426-2337254.677856667 13.8054 ENSOCUG00000026231 - UncharacterizedGL019270:24025-27477 protein [Source:UniProtKB/TrEMBL;Acc:G1U6Z7]0.45155 1.333685333 ENSOCUG00000012145 - Uncharacterized13:124170605-124202975 protein [Source:UniProtKB/TrEMBL;Acc:G1T2P6]0.754003333 2.233416 ENSOCUG00000004068 CHST8 carbohydrateAAGW02082043:12471-14866 (N-acetylgalactosamine0.502624333 4-0) sulfotransferase 1.493162333 8 [Source:HGNC Symbol;Acc:HGNC:15993] ENSOCUG00000006287 - 13:30514775-305348050.828858667 2.474433333 ENSOCUG00000006830 - Uncharacterized14:64283556-64284385 protein [Source:UniProtKB/TrEMBL;Acc:G1TVS7]0.724922667 2.169238333 ENSOCUG00000025868 GABRD gamma-aminobutyricAAGW02082845:316-8057 acid (GABA)1.122538 A receptor, delta [Source:HGNC 3.360183333 Symbol;Acc:HGNC:4084] ENSOCUG00000008464 PRKG2 protein kinase,15:69077234-69185870 cGMP-dependent,0.956610333 type II [Source:HGNC 2.864416667 Symbol;Acc:HGNC:9416] ENSOCUG00000028050 - Uncharacterized2:98143892-98256733 protein [Source:UniProtKB/TrEMBL;Acc:G1TPX4]0.976547333 2.924776667 ENSOCUG00000010340 ALOX15B arachidonate19:11157839-11351886 15-lipoxygenase, type0.593774333 B [Source:HGNC 1.783221333Symbol;Acc:HGNC:434] ENSOCUG00000009088 STEAP1 Oryctolagus10:38450971-38461653 cuniculus six transmembrane1.429391 epithelial antigen 4.371483333 of the prostate 1 (STEAP1), mRNA. [Source:RefSeq mRNA;Acc:NM_001171274] ENSOCUG00000016886 - OryctolagusGL018717:2595969-2621450 cuniculus lipophilin0.769586667 CP (LOC100008796), 2.389336667 mRNA. [Source:RefSeq mRNA;Acc:NM_001082096] ENSOCUG00000011055 NHE-3 OryctolagusGL018897:226308-236577 cuniculus Na/H exchanger0.454786667 3 (NHE-3), mRNA. 1.419509333 [Source:RefSeq mRNA;Acc:NM_001082697] ENSOCUG00000024191 - 21:4628192-48763511.853773333 5.857189 ENSOCUG00000022366 snoU85 Small nucleolar8:32552666-32579877 RNA U85 [Source:RFAM;Acc:RF01296]0.369756667 1.170993333 ENSOCUG00000000252 DIRAS2 DIRAS family,1:77463672-77464272 GTP-binding RAS-like0.814241667 2 [Source:HGNC 2.599636667 Symbol;Acc:HGNC:19323]

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ENSOCUG00000021122 - Uncharacterized2:98461325-98462005 protein [Source:UniProtKB/TrEMBL;Acc:G1TIN8]1.409720667 4.565916667 ENSOCUG00000025765 - UncharacterizedAAGW02079997:9215-48583 protein [Source:UniProtKB/TrEMBL;Acc:G1U2I8]0.446159 1.470185333 ENSOCUG00000017459 EPB42 erythrocyte 17:29060803-29079853membrane protein band0.658069333 4.2 [Source:HGNC 2.179034667 Symbol;Acc:HGNC:3381] ENSOCUG00000025226 BMP5 bone morphogenetic12:45671583-45794649 protein 5 [Source:HGNC0.413147333 Symbol;Acc:HGNC:1072] 1.368103333 ENSOCUG00000007445 PMP2 Oryctolagus3:97128687-97134093 cuniculus peripheral1.662827333 myelin protein 2 (PMP2), 5.540076667 mRNA. [Source:RefSeq mRNA;Acc:NM_001082230] ENSOCUG00000027505 SIT1 signaling threshold1:18274545-18275859 regulating transmembrane0.466230333 adaptor 1.5662076671 [Source:HGNC Symbol;Acc:HGNC:17710] ENSOCUG00000003184 - 10:23064535-230649870.365420667 1.252748 ENSOCUG00000011557 - Uncharacterized5:35535292-35546057 protein [Source:UniProtKB/TrEMBL;Acc:G1U7W7]0.316093667 1.088242333 ENSOCUG00000029280 ITLN2 intelectin 2 [Source:HGNC13:32196255-32200427 Symbol;Acc:HGNC:20599]1.72329 5.959335333 ENSOCUG00000023583 NUPR1L nuclear protein,GL018788:753417-753708 transcriptional 0.327069333regulator, 1-like [Source:HGNC 1.133056667 Symbol;Acc:HGNC:44164] ENSOCUG00000029664 - UncharacterizedGL019400:38962-40316 protein [Source:UniProtKB/TrEMBL;Acc:U3KLT3]0.501011967 1.748186267 ENSOCUG00000009954 CHST4 carbohydrate5:28013793-28014963 (N-acetylglucosamine0.372398 6-O) sulfotransferase 4 1.29986[Source:HGNC Symbol;Acc:HGNC:1972] ENSOCUG00000003128 C10orf128 chromosomeGL019147:114616-117845 10 open reading frame0.777290667 128 [Source:HGNC Symbol;Acc:HGNC:27274] 2.72834 ENSOCUG00000001157 HOXC12 homeobox C124:37739048-37742252 [Source:HGNC Symbol;Acc:HGNC:5124]0.50463 1.784233333 ENSOCUG00000001864 AQP8 aquaporin 8 6:15707665-15718213[Source:HGNC Symbol;Acc:HGNC:642]1.197601 4.240723333 ENSOCUG00000001662 SLC7A11 solute carrier15:26381719-26463044 family 7 (anionic 0.838137333amino acid transporter 2.970946667light chain, xc- system), member 11 [Source:HGNC Symbol;Acc:HGNC:11059] ENSOCUG00000003931 GJA3 gap junction8:44489785-44491113 protein, alpha 3, 46kDa0.737026 [Source:HGNC Symbol;Acc:HGNC:4277] 2.615041333 ENSOCUG00000025452 - Uncharacterized16:80262369-80262721 protein [Source:UniProtKB/TrEMBL;Acc:G1TFS1]0.544123333 1.962246667 ENSOCUG00000010243 - Uncharacterized11:64148585-64154358 protein [Source:UniProtKB/TrEMBL;Acc:G1SYX0]0.614643667 2.241785 ENSOCUG00000002208 - Uncharacterized19:17214856-17246213 protein [Source:UniProtKB/TrEMBL;Acc:G1SH21]0.359243333 1.313743333 ENSOCUG00000015146 - UncharacterizedGL018764:278149-278404 protein [Source:UniProtKB/TrEMBL;Acc:G1T8U1]1.38211 5.09245 ENSOCUG00000024602 - 7:146971791-1469722760.401887333 1.509735 ENSOCUG00000001208 RXFP1 relaxin/insulin-likeDraftGL018701:1096778-1246151 family peptide0.604177333 receptor 1 [Source:HGNC 2.269936667 Symbol;Acc:HGNC:19718] ENSOCUG00000013533 IGHM immunoglobulinGL019133:19253-172606 heavy constant mu1.057376 [Source:HGNC Symbol;Acc:HGNC:5541] 3.972820333 ENSOCUG00000026223 - Uncharacterized21:7796448-7839233 protein [Source:UniProtKB/TrEMBL;Acc:G1TR77]0.303056333 1.142250333 ENSOCUG00000003339 C11orf71 chromosome1:101995865-102006231 11 open reading frame0.525226333 71 [Source:HGNC 2.051922333 Symbol;Acc:HGNC:25937] ENSOCUG00000029191 - Uncharacterized21:4586405-4587181 protein [Source:UniProtKB/TrEMBL;Acc:G1TP36]0.696014667 2.731580667 ENSOCUG00000027644 TSPO2 translocator 12:30790392-30791479protein 2 [Source:HGNC0.438137667 Symbol;Acc:HGNC:21256] 1.762885667 ENSOCUG00000010287 SAPCD2 suppressor APCGL018999:5725-30429 domain containing0.303073 2 [Source:HGNC Symbol;Acc:HGNC:28055] 1.220324333 ENSOCUG00000002609 NRGN 1:92485617-924858360.632243333 2.597566667 ENSOCUG00000009208 ACVR1C activin A receptor,7:96337172-96439921 type IC [Source:HGNC1.046276333 Symbol;Acc:HGNC:18123] 4.36883 ENSOCUG00000023724 - Uncharacterized2:98627905-98631332 protein [Source:UniProtKB/TrEMBL;Acc:G1U8X8]0.269577667 1.136604333 ENSOCUG00000006893 MARCO macrophage7:63885199-63921386 receptor with collagenous0.823379333 structure [Source:HGNC 3.502337333 Symbol;Acc:HGNC:6895] ENSOCUG00000027233 - Uncharacterized19:12931245-12931611 protein [Source:UniProtKB/TrEMBL;Acc:G1U1Q7]1.189971667 5.08188 ENSOCUG00000022958 - UncharacterizedGL018758:1318841-1319349 protein [Source:UniProtKB/TrEMBL;Acc:G1U5G1]0.617884 2.647823333 ENSOCUG00000022477 ALOX12 arachidonate19:12173029-12182538 15-lipoxygenase [Source:RefSeq0.761354 peptide;Acc:NP_001075751] 3.900773667 ENSOCUG00000014832 STEAP2 Oryctolagus10:38390802-38404595 cuniculus six transmembrane0.390523333 epithelial antigen 2.01984 of the prostate 2 (STEAP2), mRNA. [Source:RefSeq mRNA;Acc:NM_001171275] ENSOCUG00000026955 - GL018747:705741-7064100.234284 1.215015 ENSOCUG00000009086 KLB klotho beta [Source:HGNC2:28738439-28780947 Symbol;Acc:HGNC:15527]1.298456667 6.877696667 ENSOCUG00000024749 - UncharacterizedAAGW02079587:75714-76035 protein [Source:UniProtKB/TrEMBL;Acc:G1U177]0.220450333 1.197746667 ENSOCUG00000010761 NPY Oryctolagus10:9173130-9180391 cuniculus neuropeptide0.231228667 Y (NPY), mRNA. [Source:RefSeq 1.274295 mRNA;Acc:NM_001160286] ENSOCUG00000019570 7SK 7SK RNA [Source:RFAM;Acc:RF00100]7:12854278-12854593 0.245793 1.37086 ENSOCUG00000024878 HIST1H2AChistone cluster12:10943920-10944313 1, H2ac [Source:HGNC0.59779 Symbol;Acc:HGNC:4733] 3.467386667 ENSOCUG00000004420 - UncharacterizedGL018810:881758-883329 protein [Source:UniProtKB/TrEMBL;Acc:G1SLS4]0.229043333 1.330296667 ENSOCUG00000011138 ASIP Oryctolagus4:5435026-5460609 cuniculus agouti signaling0.441273333 protein (ASIP), 2.618416667 mRNA. [Source:RefSeq mRNA;Acc:NM_001122939] ENSOCUG00000027760 - UncharacterizedAAGW02079587:63109-63915 protein [Source:UniProtKB/TrEMBL;Acc:G1U5Y2]0.206191333 1.256665667 ENSOCUG00000000407 DCT dopachrome8:96366061-96407953 tautomerase [Source:HGNC0.609787667 Symbol;Acc:HGNC:2709] 3.825333333 ENSOCUG00000025501 - UncharacterizedGL019618:5430-34954 protein [Source:UniProtKB/TrEMBL;Acc:G1U7M5]0.201555 1.320265333 ENSOCUG00000026224 HAMP hepcidin antimicrobialGL018786:196797-198697 peptide [Source:HGNC0.241785333 Symbol;Acc:HGNC:15598] 1.636441333 ENSOCUG00000029041 MMP23B matrix metallopeptidaseGL018828:292421-292940 23B [Source:HGNC0.155864333 Symbol;Acc:HGNC:7171] 1.089520333

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ENSOCUG00000017845 MAB21L1 mab-21-likeGL018702:5856651-6485163 1 (C. elegans) [Source:HGNC0.379245 Symbol;Acc:HGNC:6757] 2.79361 ENSOCUG00000024556 - UncharacterizedAAGW02082420:1657-1984 protein [Source:UniProtKB/TrEMBL;Acc:G1TYZ5]0.187713 1.422983333 ENSOCUG00000018579 7SK 7SK RNA [Source:RFAM;Acc:RF00100]6:12774571-128351140.219948667 1.677423333 ENSOCUG00000025369 CLDN17 claudin 17 [Source:HGNC14:159698047-159698722 Symbol;Acc:HGNC:2038]0.223600333 1.723762333 ENSOCUG00000025011 snoU89 Small nucleolar8:32968632-32972750 RNA U89 [Source:RFAM;Acc:RF01294]0.421433333 3.268873333 ENSOCUG00000015546 SLC24A4 solute carrier20:13497996-13638066 family 24 (sodium/potassium/calcium0.131180933 exchanger), 1.022830667 member 4 [Source:HGNC Symbol;Acc:HGNC:10978] ENSOCUG00000027375 - Uncharacterized12:111600039-111600357 protein [Source:UniProtKB/TrEMBL;Acc:G1U0B4]0.179472333 1.434786667 ENSOCUG00000009965 TYR Oryctolagus1:127562606-127667237 cuniculus tyrosinase0.194426933 (oculocutaneous albinism 1.770066 IA) (TYR), mRNA. [Source:RefSeq mRNA;Acc:NM_001082077] ENSOCUG00000023644 7SK 7SK RNA [Source:RFAM;Acc:RF00100]12:122542972-1226443910.164045333 1.49551 ENSOCUG00000016646 C10orf67 chromosomeGL018724:270-8457 10 open reading frame0.125553667 67 [Source:HGNC 1.200549667 Symbol;Acc:HGNC:28716] ENSOCUG00000010189 OB Oryctolagus7:16060258-16081777 cuniculus leptin (LEP),0.297447667 mRNA. [Source:RefSeq 3.438422667 mRNA;Acc:NM_001163069] ENSOCUG00000026355 GSC OryctolagusGL018909:100942-102439 cuniculus goosecoid homeobox0.233999 (GSC), mRNA. 3.052023333 [Source:RefSeq mRNA;Acc:NM_001099959] ENSOCUG00000029335 - Uncharacterized21:4588833-4590784 protein [Source:UniProtKB/TrEMBL;Acc:G1TT86]0.078496167 1.055434367 ENSOCUG00000011093 TRAV19 T cell receptor17:42308559-42310649 alpha variable 19 [Source:HGNC0.062193 Symbol;Acc:HGNC:12115] 1.940761667 ENSOCUG00000021336 TRAV5 T cell receptor17:42101153-42101656 alpha variable 5 [Source:HGNC1.00E-05 Symbol;Acc:HGNC:12143] 1.125755333 ENSOCUG00000022215 - UncharacterizedGL019864:939-3529 protein [Source:UniProtKB/TrEMBL;Acc:G1U8Y0]1.00E-05 1.128003333 ENSOCUG00000028265 SCARNA13 Small Cajal 17:68772479-68772753body specific RNA 13 1.00E-05[Source:RFAM;Acc:RF00231] 1.141256667 ENSOCUG00000028173 - Uncharacterized2:98585815-98586463 protein [Source:UniProtKB/TrEMBL;Acc:G1THD3]1.00E-05 1.162463333 ENSOCUG00000013324 HCRT hypocretin (orexin)19:43002828-43003940 neuropeptide precursor1.00E-05 [Source:HGNC 1.173685333 Symbol;Acc:HGNC:4847] ENSOCUG00000026861 - UncharacterizedGL019260:96165-96914 protein [Source:UniProtKB/TrEMBL;Acc:G1U7V2]1.00E-05 1.210323333 ENSOCUG00000028651 7SK 7SK RNA [Source:RFAM;Acc:RF00100]X:37669041-376692511.00E-05 1.324093333 ENSOCUG00000028534 SCARNA13 Small Cajal GL019009:60208-60482body specific RNA 13 1.00E-05[Source:RFAM;Acc:RF00231] 1.456773333 ENSOCUG00000022649 APLN UncharacterizedDraftX:104073868-104080730 protein [Source:UniProtKB/TrEMBL;Acc:G1TTT0]1.00E-05 1.49757 ENSOCUG00000025864 - UncharacterizedGL019480:44302-45623 protein [Source:UniProtKB/TrEMBL;Acc:G1TTX3]1.00E-05 1.69256 ENSOCUG00000018249 SNORA73 Small nucleolar13:137020463-137020666 RNA SNORA73 family1.00E-05 [Source:RFAM;Acc:RF00045] 1.791583333 ENSOCUG00000009468 GNG3 guanine nucleotideGL018717:1635611-1636080 binding protein 1.00E-05(G protein), gamma 1.886516667 3 [Source:HGNC Symbol;Acc:HGNC:4405] ENSOCUG00000019656 SNORA74 Small nucleolar18:5991800-6012425 RNA SNORA74 [Source:RFAM;Acc:RF00090]1.00E-05 2.376926667 ENSOCUG00000002853 VGF VGF nerve growthGL018831:68997-69504 factor inducible 1.00E-05[Source:HGNC Symbol;Acc:HGNC:12684] 2.400596 ENSOCUG00000023180 - Uncharacterized2:98664529-98889753 protein [Source:UniProtKB/TrEMBL;Acc:G1TWR0]1.00E-05 2.559893333 ENSOCUG00000022854 - UncharacterizedGL019739:45761-46130 protein [Source:UniProtKB/TrEMBL;Acc:G1U883]1.00E-05 2.563186667 ENSOCUG00000028699 U2 U2 spliceosomal12:127281689-127362458 RNA [Source:RFAM;Acc:RF00004]1.00E-05 3.103563333 ENSOCUG00000012715 TBX5 T-box 5 [Source:HGNC21:9757706-9806915 Symbol;Acc:HGNC:11604]1.00E-05 3.583366667 ENSOCUG00000014604 TMPRSS11Etransmembrane15:81370128-81462483 protease, serine 11E 16.6667[Source:HGNC Symbol;Acc:HGNC:24465] 38.63506667 ENSOCUG00000022767 - Uncharacterized7:4123778-4123931 protein [Source:UniProtKB/TrEMBL;Acc:G1U865]15.3201 35.015 ENSOCUG00000000501 KRT82 keratin 82 [Source:HGNC4:36457147-36466469 Symbol;Acc:HGNC:6459]13.9974 36.68553333 ENSOCUG00000024778 - Uncharacterized19:42055045-42055345 protein [Source:UniProtKB/TrEMBL;Acc:G1U771]51.31616667 128.7837333 ENSOCUG00000007342 DSG4 desmoglein 9:72638264-726635624 [Source:HGNC Symbol;Acc:HGNC:21307]13.80638667 30.1153 ENSOCUG00000017905 PCK1 phosphoenolpyruvateGL019719:4743-9944 carboxykinase9.04342 1 (soluble) [Source:HGNC 26.71173333 Symbol;Acc:HGNC:8724] ENSOCUG00000013802 ALDOC aldolase C, fructose-bisphosphate19:19580208-1958339310.33132333 [Source:HGNC Symbol;Acc:HGNC:418] 24.06363333 ENSOCUG00000021675 - Uncharacterized19:42105938-42106334 protein [Source:UniProtKB/TrEMBL;Acc:G1TFG3]41.174 104.9704 ENSOCUG00000027394 - Uncharacterized2:98143892-98256733 protein [Source:UniProtKB/TrEMBL;Acc:G1TRK9]7.71983 22.62971333 ENSOCUG00000000725 MC5R melanocortin9:48336917-48337907 5 receptor [Source:HGNC5.318493333 Symbol;Acc:HGNC:6933] 16.72933 ENSOCUG00000016071 ELOVL3 ELOVL fatty18:50222047-50228175 acid elongase 3 [Source:HGNC6.72973 Symbol;Acc:HGNC:18047] 13.36550667 ENSOCUG00000026053 MYCN v-myc avian2:164905474-164906539 myelocytomatosis 6.262503333viral oncogene neuroblastoma 13.14029333 derived homolog [Source:HGNC Symbol;Acc:HGNC:7559] ENSOCUG00000017782 ACE2 angiotensin X:1396877-1444360I converting enzyme6.198853333 2 [Source:HGNC Symbol;Acc:HGNC:13557] 13.41788333 ENSOCUG00000023092 - Uncharacterized4:36335214-36340265 protein [Source:UniProtKB/TrEMBL;Acc:G1U7T6]4.504123333 14.75333667 ENSOCUG00000029278 KRT78 keratin 78 [Source:HGNC4:36772250-36779016 Symbol;Acc:HGNC:28926]5.319533333 12.35142667 ENSOCUG00000015615 KRTAP3-1 keratin associated19:42066966-42067263 protein 3-1 [Source:HGNC674.4783333 Symbol;Acc:HGNC:16778] 1591.683667 ENSOCUG00000023053 - Uncharacterized19:42315360-42315645 protein [Source:UniProtKB/TrEMBL;Acc:G1TKG6]46.20983333 118.8643333 ENSOCUG00000007460 SOD3 Oryctolagus2:15391092-15391827 cuniculus superoxide19.27243333 dismutase 3, extracellular 51.47133333 (SOD3), mRNA. [Source:RefSeq mRNA;Acc:NM_001082632]

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ENSOCUG00000003849 C6orf226 chromosome12:32419040-32419208 6 open reading frame5.965666667 226 [Source:HGNC 11.36153333 Symbol;Acc:HGNC:34431] ENSOCUG00000001230 XDH xanthine dehydrogenase2:154726271-154792957 [Source:HGNC5.949923333 Symbol;Acc:HGNC:12805] 11.83316 ENSOCUG00000021249 - Uncharacterized13:38994111-38995247 protein [Source:UniProtKB/TrEMBL;Acc:G1TIX1]5.299616667 11.55007667 ENSOCUG00000026651 - UncharacterizedGL019133:19253-172606 protein [Source:UniProtKB/TrEMBL;Acc:G1THZ6]3.743377667 12.03156633 ENSOCUG00000009045 ASS1 argininosuccinateGL019049:104851-141752 synthase 1 [Source:HGNC3.38385 Symbol;Acc:HGNC:758] 12.18141333 ENSOCUG00000005302 CIDEC cell death-inducingGL018802:334729-336651 DFFA-like 3.978993333effector c [Source:HGNC 11.00131333 Symbol;Acc:HGNC:24229] ENSOCUG00000024526 - Uncharacterized2:98664529-98889753 protein [Source:UniProtKB/TrEMBL;Acc:G1TZR6]3.817931333 11.76538667 ENSOCUG00000022099 - UncharacterizedGL019218:65532-65700 protein [Source:UniProtKB/TrEMBL;Acc:G1TWS5]20.88821 45.4856 ENSOCUG00000029454 AADACL2 arylacetamide14:45754232-45785470 deacetylase-like 4.3105333332 [Source:HGNC Symbol;Acc:HGNC:24427] 9.35858 ENSOCUG00000005355 - 19:42151610-42226613 4.16098 9.574283333 ENSOCUG00000025985 - Uncharacterized4:36407432-36420645 protein [Source:UniProtKB/TrEMBL;Acc:G1TJG8]14.61788667 39.19756667 ENSOCUG00000017620 - OryctolagusGL018733:2179752-2184430 cuniculus serum amyloid2.960006667 protein A (LOC100009259), 9.916707 mRNA. [Source:RefSeq mRNA;Acc:NM_001082392] ENSOCUG00000003668 LCK LCK proto-oncogene,GL018704:5907642-5916977 Src family3.976513333 tyrosine kinase [Source:HGNC 7.05741 Symbol;Acc:HGNC:6524] ENSOCUG00000013829 KCTD4 potassium channel8:49843111-49974880 tetramerization domain3.71446 containing 4 7.920183333 [Source:HGNC Symbol;Acc:HGNC:23227] ENSOCUG00000005636 - UncharacterizedGL018810:884856-890885 protein [Source:UniProtKB/TrEMBL;Acc:G1SPC7]3.351413333 7.2229 ENSOCUG00000014207 ELF5 E74-like factor1:173764070-173797132 5 (ets domain transcription3.023756667 factor) [Source:HGNC 7.96725 Symbol;Acc:HGNC:3320] ENSOCUG00000010762 CHAC1 ChaC, cation17:31128126-31132281 transport regulator14.28763333 homolog 1 (E. coli) [Source:HGNC 32.21733333 Symbol;Acc:HGNC:28680] ENSOCUG00000009827 TUBB2A tubulin, betaGL018715:2500647-2543365 2A class IIa [Source:HGNC13.57597 Symbol;Acc:HGNC:12412] 29.95286667 ENSOCUG00000023380 CYP3A6 OryctolagusGL018760:606715-640385 cuniculus cytochrome3.934346667 P450 3A6 (CYP3A6), 6.013876667 mRNA. [Source:RefSeq mRNA;Acc:NM_001171268] ENSOCUG00000010465 EPHA3 EPH receptor14:127467602-127859546 A3 [Source:HGNC3.823623333 Symbol;Acc:HGNC:3387] 6.00033 ENSOCUG00000003157 DCBLD1 discoidin, CUB12:106423324-106501906 and LCCL domain3.946113333 containing 1 [Source:HGNC 6.215593333 Symbol;Acc:HGNC:21479] ENSOCUG00000028069 - Uncharacterized2:98904825-98905143 protein [Source:UniProtKB/TrEMBL;Acc:G1TI63]3.98422 6.336808333 ENSOCUG00000017475 ZBTB37 zinc fingerDraft and13:1212723-1229753 BTB domain containing3.852053333 37 [Source:HGNC 6.127976667 Symbol;Acc:HGNC:28365] ENSOCUG00000016706 KIF11 kinesin family18:40400751-40462364 member 11 [Source:HGNC3.906093333 Symbol;Acc:HGNC:6388] 6.21591 ENSOCUG00000013023 GK UncharacterizedX:16742329-16821302 protein [Source:UniProtKB/TrEMBL;Acc:G1T4K8]3.805396667 6.1646 ENSOCUG00000006361 FAM180B family with 1:186905992-186907533sequence similarity3.791463333 180, member B [Source:HGNC 6.157566667 Symbol;Acc:HGNC:34451] ENSOCUG00000008600 FPR OryctolagusGL018792:120304-124288 cuniculus N-formyl peptide3.70059 receptor (FPR), 6.020786667 mRNA. [Source:RefSeq mRNA;Acc:NM_001082314] ENSOCUG00000023825 SNCA synuclein, alpha15:60162752-60288229 (non A4 component3.72031 of amyloid precursor) 6.147736667 [Source:HGNC Symbol;Acc:HGNC:11138] ENSOCUG00000008504 CD300LG CD300 molecule-like19:44263382-44275516 family member3.988673333 g [Source:HGNC Symbol;Acc:HGNC:30455] 6.61095 ENSOCUG00000003970 TAGLN3 transgelin 3 14:107184558-107199342[Source:HGNC Symbol;Acc:HGNC:29868]3.614453333 6.00644 ENSOCUG00000011972 EBF2 early B-cell 2:43639033-43844581factor 2 [Source:HGNC3.881473333 Symbol;Acc:HGNC:19090] 6.594096667 ENSOCUG00000004719 TNFAIP8L2 Oryctolagus13:41040253-41040808 cuniculus tumor necrosis3.921163333 factor, alpha-induced protein 6.7017 8-like 2 (TNFAIP8L2), mRNA. [Source:RefSeq mRNA;Acc:NM_001171296] ENSOCUG00000003142 AR Androgen receptorX:46288422-46477127 [Source:UniProtKB/TrEMBL;Acc:G1TTV8]3.78285 6.60129 ENSOCUG00000006003 ERP27 endoplasmic8:24645926-24665792 reticulum protein 27 [Source:HGNC3.567175 Symbol;Acc:HGNC:26495] 6.747026667 ENSOCUG00000021520 RASD2 RASD family,GL019302:69042-74964 member 2 [Source:HGNC3.501166667 Symbol;Acc:HGNC:18229] 6.7593 ENSOCUG00000015927 CITED4 Cbp/p300-interacting13:125716683-125717232 transactivator,3.503213333 with Glu/Asp-rich 6.932386667 carboxy-terminal domain, 4 [Source:HGNC Symbol;Acc:HGNC:18696] ENSOCUG00000021409 - Uncharacterized20:14335870-14385264 protein [Source:UniProtKB/TrEMBL;Acc:G1TQG8]3.198942333 6.605353333 ENSOCUG00000015593 KRT39 keratin 39 [Source:HGNC19:42005627-42014854 Symbol;Acc:HGNC:32971]29.30243333 65.12703333 ENSOCUG00000023482 SP6 Sp6 transcription19:39489780-39491535 factor [Source:HGNC12.03303 Symbol;Acc:HGNC:14530] 27.86526667 ENSOCUG00000023989 - Uncharacterized2:98469700-98477100 protein [Source:UniProtKB/TrEMBL;Acc:G1U679]1.049253333 7.050029667 ENSOCUG00000012398 SLC30A1 solute carrier16:61352241-61353147 family 30 (zinc transporter),27.5823 member 1 [Source:HGNC 61.2351 Symbol;Acc:HGNC:11012] ENSOCUG00000010870 CLMN calmin (calponin-like,GL018909:424482-448646 transmembrane)2.966573333 [Source:HGNC 5.073766667 Symbol;Acc:HGNC:19972] ENSOCUG00000027615 - UncharacterizedGL018806:510028-510901 protein [Source:UniProtKB/TrEMBL;Acc:G1TIT2]2.746173667 5.003370333 ENSOCUG00000006381 LY86 lymphocyte 12:362030-430827antigen 86 [Source:HGNC2.80954 Symbol;Acc:HGNC:16837] 5.189996667 ENSOCUG00000027805 PLCXD2 phosphatidylinositol-specific14:107473746-107533072 phospholipase2.979693333 C, X domain containing 5.83939 2 [Source:HGNC Symbol;Acc:HGNC:26462] ENSOCUG00000008329 ADAMTS19ADAM metallopeptidase3:12993929-13213958 with thrombospondin2.412195333 type 1 5.070086667motif, 19 [Source:HGNC Symbol;Acc:HGNC:17111] ENSOCUG00000001968 COL9A3 collagen, typeGL019426:89-19816 IX, alpha 3 [Source:HGNC2.619656667 Symbol;Acc:HGNC:2219] 5.898216667 ENSOCUG00000007677 - Uncharacterized13:126722246-126752118 protein [Source:UniProtKB/TrEMBL;Acc:G1STJ6]2.36484 5.386623333 ENSOCUG00000022798 - chromosome2:93046295-93046799 2 open reading frame2.141992333 15 [Source:HGNC 5.129496667Symbol;Acc:HGNC:28436] ENSOCUG00000014595 TBX3 T-box 3 [Source:HGNC21:9981802-9992628 Symbol;Acc:HGNC:11602]2.360853333 5.97282

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ENSOCUG00000002875 STOX1 storkhead box18:17857506-17894978 1 [Source:HGNC2.212096667 Symbol;Acc:HGNC:23508] 5.61857 ENSOCUG00000029489 - UncharacterizedAAGW02083711:895-2887 protein [Source:UniProtKB/TrEMBL;Acc:U3KNX1]26.17462333 59.03168667 ENSOCUG00000014497 EFHD1 EF-hand domainGL018736:218081-268189 family, member11.13194667 D1 [Source:HGNC Symbol;Acc:HGNC:29556] 24.28383333 ENSOCUG00000009880 DUSP14 dual specificity19:25440409-25441006 phosphatase 14 24.92663333[Source:HGNC Symbol;Acc:HGNC:17007] 53.56686667 ENSOCUG00000011173 - Uncharacterized19:42417523-42422771 protein [Source:UniProtKB/TrEMBL;Acc:G1TL31]20.35146 56.95026667 ENSOCUG00000022878 C1orf53 chromosome16:73301247-73302669 1 open reading frame 20.0101453 [Source:HGNC Symbol;Acc:HGNC:30003] 56.4038 ENSOCUG00000015331 GPRC5D G protein-coupled8:26808777-26819262 receptor, class58.02383333 C, group 5, member 149.4059333D [Source:HGNC Symbol;Acc:HGNC:13310] ENSOCUG00000006802 LCORL ligand dependent2:8406292-8620864 nuclear receptor2.954113333 corepressor-like [Source:HGNC 4.178353333 Symbol;Acc:HGNC:30776] ENSOCUG00000010209 CLDN15 claudin 15 [Source:HGNCGL018831:262458-265434 Symbol;Acc:HGNC:2036]2.95895 4.2383 ENSOCUG00000001171 NUF2 NUF2, NDC8013:29603369-29628912 kinetochore complex2.768123333 component [Source:HGNC 4.01928 Symbol;Acc:HGNC:14621] ENSOCUG00000015108 - 7:159539257-1595403252.997216667 4.361306667 ENSOCUG00000026716 MBLAC2 metallo-beta-lactamase11:10219995-10236353 domain containing2.7893 2 [Source:HGNC 4.134826667 Symbol;Acc:HGNC:33711] ENSOCUG00000025990 PRSS27 protease, serineGL018828:36918-42473 27 [Source:HGNC2.773933333 Symbol;Acc:HGNC:15475] 4.149983333 ENSOCUG00000003535 CP ceruloplasmin14:42928394-43043225 (ferroxidase) [Source:HGNC2.85923 Symbol;Acc:HGNC:2295] 4.279366667 ENSOCUG00000027782 MSMP microseminoprotein,1:18090637-18256037 prostate associated2.710991 [Source:HGNC Symbol;Acc:HGNC:29663] 4.08488 ENSOCUG00000001437 - GL018914:390239-3914332.610386667 4.007493333 ENSOCUG00000003204 MAP3K9 mitogen-activatedGL018749:384439-457357 protein kinase kinase2.807212 kinase 9 [Source:HGNC 4.34948 Symbol;Acc:HGNC:6861] ENSOCUG00000025420 EID2B EP300 interacting5:462544-462943 inhibitor of differentiation2.807646667 2B [Source:HGNC 4.410546667 Symbol;Acc:HGNC:26796] ENSOCUG00000025618 PRR7 proline rich 3:57965128-579655547 (synaptic) [Source:HGNC2.769646667 Symbol;Acc:HGNC:28130] 4.384843333 ENSOCUG00000009840 SLC46A2 solute carrier1:456316-467089 family 46, member2.880703333 2 [Source:HGNC Symbol;Acc:HGNC:16055] 4.570346667 ENSOCUG00000008207 CAPN8 calpain 8 [Source:HGNC16:49562605-49632940 Symbol;Acc:HGNC:1485]2.543743333 4.051963333 ENSOCUG00000013808 GPR68 G protein-coupled20:14488205-14489333 receptor 68 [Source:HGNC2.769563333 Symbol;Acc:HGNC:4519] 4.477196667 ENSOCUG00000007896 MILR1 mast Draftcell immunoglobulin-like19:49297509-49311971 2.508773333receptor 1 [Source:HGNC 4.181866667 Symbol;Acc:HGNC:27570] ENSOCUG00000022891 NOVA2 neuro-oncologicalGL019168:90128-119831 ventral antigen2.809806667 2 [Source:HGNC Symbol;Acc:HGNC:7887] 4.74119 ENSOCUG00000011780 CYFIP2 cytoplasmic3:38752688-38858378 FMR1 interacting protein2.351143333 2 [Source:HGNC Symbol;Acc:HGNC:13760] 4.03425 ENSOCUG00000027617 - GL019085:10576-234182.790073333 4.82811 ENSOCUG00000002901 - UncharacterizedGL018806:308526-309399 protein [Source:UniProtKB/TrEMBL;Acc:G1TG24]2.373363 4.109770667 ENSOCUG00000010624 POLR3G polymerase 11:10247400-10269842(RNA) III (DNA directed)2.813543333 polypeptide G (32kD) 4.92549 [Source:HGNC Symbol;Acc:HGNC:30075] ENSOCUG00000007182 GAS2L3 growth arrest-specific4:79820997-79849254 2 like 3 [Source:HGNC2.289923333 Symbol;Acc:HGNC:27475] 4.022866667 ENSOCUG00000009277 RND2 Rho family 19:43698416-43703885GTPase 2 [Source:HGNC2.549446667 Symbol;Acc:HGNC:18315] 4.612143333 ENSOCUG00000023337 HOXB3 homeobox B319:38497780-38830939 [Source:HGNC Symbol;Acc:HGNC:5114]2.404633333 4.404326667 ENSOCUG00000014362 ITGAL integrin, alphaGL018752:1690348-1744706 L (antigen CD11A2.294422333 (p180), lymphocyte 4.247367333function-associated antigen 1; alpha polypeptide) [Source:HGNC Symbol;Acc:HGNC:6148] ENSOCUG00000007526 CTH cystathionine13:95622494-95651626 gamma-lyase [Source:HGNC2.341996667 Symbol;Acc:HGNC:2501] 4.500646667 ENSOCUG00000004261 SLC35G1 solute carrier18:41585682-41592536 family 35, member2.449236667 G1 [Source:HGNC Symbol;Acc:HGNC:26607] 4.86335 ENSOCUG00000011441 - solute carrier8:5864933-5865158 family 2 (facilitated2.381616667 glucose transporter), 4.791443333 member 13 [Source:HGNC Symbol;Acc:HGNC:15956] ENSOCUG00000011230 MMP16 matrix metallopeptidase3:103464757-103759232 16 (membrane-inserted)2.064953333 [Source:HGNC 4.17235 Symbol;Acc:HGNC:7162] ENSOCUG00000026950 - UncharacterizedGL019171:96730-104301 protein [Source:UniProtKB/TrEMBL;Acc:G1TH77]2.027043333 4.341756667 ENSOCUG00000018292 7SK 7SK RNA [Source:RFAM;Acc:RF00100]11:11665904-116662252.240676667 4.86655 ENSOCUG00000014767 PAG1 phosphoprotein3:96655556-96668735 membrane anchor with2.07418 glycosphingolipid microdomains 4.5711 1 [Source:HGNC Symbol;Acc:HGNC:30043] ENSOCUG00000017793 CD38 Oryctolagus2:6298523-6341542 cuniculus CD38 molecule2.234327667 (CD38), mRNA. 4.997563333 [Source:RefSeq mRNA;Acc:NM_001082683] ENSOCUG00000016256 HAND2 heart and neural2:51438992-51442863 crest derivatives0.046627667 expressed 2 [Source:HGNC 5.0414 Symbol;Acc:HGNC:4808] ENSOCUG00000029124 - Uncharacterized2:98481563-98539867 protein [Source:UniProtKB/TrEMBL;Acc:G1U0D0]1.00E-05 5.101146667 ENSOCUG00000021624 GNPTG N-acetylglucosamine-1-phosphateAAGW02083152:6776-7108 transferase,1.00E-05 gamma subunit 5.3016 [Source:HGNC Symbol;Acc:HGNC:23026] ENSOCUG00000003454 PRDM6 PR domain containing3:7295523-7386180 6 [Source:HGNC0.772645333 Symbol;Acc:HGNC:9350] 4.304963333 ENSOCUG00000017941 - Oryctolagus15:76281018-76281825 cuniculus platelet microbicidal0.544083 protein 1 (LOC100008921), 4.044773333 mRNA. [Source:RefSeq mRNA;Acc:NM_001082162] ENSOCUG00000004318 PRM3 protamine 36:4835743-4836010 [Source:HGNC Symbol;Acc:HGNC:13732]1.00E-05 4.150166667 ENSOCUG00000028998 - Uncharacterized13:39247798-39352888 protein [Source:UniProtKB/TrEMBL;Acc:G1U9F4]1.00E-05 4.1879 ENSOCUG00000025346 - UncharacterizedGL018714:170246-170456 protein [Source:UniProtKB/TrEMBL;Acc:G1U117]1.00E-05 4.227533333 ENSOCUG00000015682 - OryctolagusGL018717:2641283-2644386 cuniculus lipophilin AL21.00E-05 (LOC100008880), 4.244593333 mRNA. [Source:RefSeq mRNA;Acc:NM_001082139] ENSOCUG00000020067 SNORA81 Small nucleolar14:78838990-78845089 RNA SNORA81 [Source:RFAM;Acc:RF01241]1.00E-05 4.493966667

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ENSOCUG00000018026 U3 Small nucleolar19:29323714-29763354 RNA U3 [Source:RFAM;Acc:RF00012]1.00E-05 4.718743333 ENSOCUG00000001156 HOXC13 homeobox C134:37314596-37730050 [Source:HGNC19.42003333 Symbol;Acc:HGNC:5125] 41.6063 ENSOCUG00000006938 CSDC2 cold shock domainGL018734:920530-929320 containing C2,7.760876667 RNA binding [Source:HGNC 15.13086 Symbol;Acc:HGNC:30359] ENSOCUG00000015168 PLB1 Oryctolagus2:157459246-157583846 cuniculus phospholipase7.710403333 B1 (PLB1), mRNA. 15.49623333 [Source:RefSeq mRNA;Acc:NM_001101708] ENSOCUG00000027219 IGJ immunoglobulin15:79302091-79312845 J polypeptide, 7.293583333linker protein for immunoglobulin 15.01868 alpha and mu polypeptides [Source:HGNC Symbol;Acc:HGNC:5713] ENSOCUG00000009450 ARHGAP18 Rho GTPase12:119574316-119704600 activating protein 7.95992666718 [Source:HGNC Symbol;Acc:HGNC:21035] 14.1733 ENSOCUG00000003423 SDR9C7 short chain dehydrogenase/reductaseGL018714:112056-1221147.79285 family 9C, member 14.10433333 7 [Source:HGNC Symbol;Acc:HGNC:29958] ENSOCUG00000009993 DACT2 dishevelled-bindingGL018930:322782-331978 antagonist 7.467833333of beta-catenin 2 [Source:HGNC 14.2987 Symbol;Acc:HGNC:21231] ENSOCUG00000002140 DACH1 dachshund family8:72792975-73230465 transcription factor7.10093 1 [Source:HGNC 14.14693333 Symbol;Acc:HGNC:2663] ENSOCUG00000027057 - Uncharacterized14:45824745-45848297 protein [Source:UniProtKB/TrEMBL;Acc:G1TUU8]7.002896667 14.03551667 ENSOCUG00000008934 IL12RB2 interleukin 1213:98857166-98942169 receptor, beta 2 [Source:HGNC1.98756 Symbol;Acc:HGNC:5972] 2.029033333 ENSOCUG00000000875 FAM124A family with GL018705:4965200-5039693sequence similarity 124A1.94971 [Source:HGNC Symbol;Acc:HGNC:26413] 2.0432 ENSOCUG00000011321 - Uncharacterized15:43899994-43926767 protein [Source:UniProtKB/TrEMBL;Acc:G1T132]1.866493333 2.006633333 ENSOCUG00000009941 KIAA0226L KIAA0226-like8:48785358-48827164 [Source:HGNC Symbol;Acc:HGNC:20420]1.90937 2.058543333 ENSOCUG00000007339 PLCB1 phospholipase4:27356194-27657633 C, beta 1 (phosphoinositide-specific)1.95906 [Source:HGNC 2.12927 Symbol;Acc:HGNC:15917] ENSOCUG00000001178 FAM78B family with 13:26731584-26821921sequence similarity 78, member1.98062 B [Source:HGNC 2.15293 Symbol;Acc:HGNC:13495] ENSOCUG00000014388 ZCWPW1 zinc finger, 6:27371701-27396614CW type with PWWP1.980933333 domain 1 [Source:HGNC 2.154246667 Symbol;Acc:HGNC:23486] ENSOCUG00000023919 - Uncharacterized15:46197816-46198422 protein [Source:UniProtKB/TrEMBL;Acc:G1TI08]1.88962 2.066459667 ENSOCUG00000023661 - Uncharacterized2:54577241-54577768 protein [Source:UniProtKB/TrEMBL;Acc:G1TFL6]1.875723333 2.056833333 ENSOCUG00000001393 SYP synaptophysinX:33768443-33773815 [Source:HGNC Symbol;Acc:HGNC:11506]1.86881 2.059758 ENSOCUG00000011254 BEND3 BEN domain12:95165443-95203877 containing 3 [Source:HGNC1.965173333 Symbol;Acc:HGNC:23040] 2.18946 ENSOCUG00000005788 SLC22A7 Oryctolagus12:32747198-32752781 cuniculus solute carrier1.880373333 family 22 (organic anion 2.10763 transporter), member 7 (SLC22A7), mRNA. [Source:RefSeq mRNA;Acc:NM_001082642] ENSOCUG00000017084 HCN1 OryctolagusDraft11:65830627-66242659 cuniculus hyperpolarization1.876666667 activated cyclic 2.129656667 nucleotide-gated potassium channel 1 (HCN1), mRNA. [Source:RefSeq mRNA;Acc:NM_001082063] ENSOCUG00000011827 RASSF6 Ras association15:76472819-76526900 (RalGDS/AF-6)1.869993333 domain family member 6 [Source:HGNC 2.12242 Symbol;Acc:HGNC:20796] ENSOCUG00000010513 CEP55 centrosomal18:41207175-41234345 protein 55kDa [Source:HGNC1.76409 Symbol;Acc:HGNC:1161] 2.017865333 ENSOCUG00000003504 - Uncharacterized19:24566928-24580527 protein [Source:UniProtKB/TrEMBL;Acc:G1SJV1]1.94815 2.243566667 ENSOCUG00000012434 CCDC18 coiled-coil domain13:71244257-71363713 containing 181.813753333 [Source:HGNC Symbol;Acc:HGNC:30370] 2.09355 ENSOCUG00000012546 ZNF462 zinc finger protein1:6112090-6203610 462 [Source:HGNC1.951086667 Symbol;Acc:HGNC:21684] 2.259953333 ENSOCUG00000023139 - UncharacterizedGL018700:6344366-6345646 protein [Source:UniProtKB/TrEMBL;Acc:G1TWJ9]1.790230333 2.080729 ENSOCUG00000029676 ZNF214 zinc finger protein1:148494359-148507606 214 [Source:HGNC1.876593333 Symbol;Acc:HGNC:13006] 2.18309 ENSOCUG00000003812 EPHB1 EPH receptor14:28674506-29104761 B1 [Source:HGNC1.858753333 Symbol;Acc:HGNC:3392] 2.171283333 ENSOCUG00000010319 TBC1D30 TBC1 domain4:43570212-43677172 family, member 1.97195666730 [Source:HGNC Symbol;Acc:HGNC:29164] 2.311986667 ENSOCUG00000029468 ZNF83 zinc finger proteinGL018792:362544-363576 83 [Source:HGNC1.72752 Symbol;Acc:HGNC:13158] 2.040195667 ENSOCUG00000003824 - Uncharacterized3:13618039-13620338 protein [Source:UniProtKB/TrEMBL;Acc:G1SKH4]1.83478 2.17161 ENSOCUG00000011244 ESPL1 extra spindle4:37101053-37123381 pole bodies homolog1.948596667 1 (S. cerevisiae) [Source:HGNC 2.308923333 Symbol;Acc:HGNC:16856] ENSOCUG00000015480 POLE2 polymerase 17:68796257-68831922(DNA directed), epsilon1.69789 2, accessory subunit 2.029416667 [Source:HGNC Symbol;Acc:HGNC:9178] ENSOCUG00000002595 ANKRD33Bankyrin repeat11:35506668-35578649 domain 33B [Source:HGNC1.704654667 Symbol;Acc:HGNC:35240] 2.039986667 ENSOCUG00000002369 ITK IL2-inducible3:38647944-38715585 T-cell kinase [Source:HGNC1.960436667 Symbol;Acc:HGNC:6171] 2.354496667 ENSOCUG00000005253 GNAL guanine nucleotide9:50021415-50234578 binding protein1.789106667 (G protein), alpha activating 2.15826 activity polypeptide, olfactory type [Source:HGNC Symbol;Acc:HGNC:4388] ENSOCUG00000008092 ACOT11 acyl-CoA thioesterase13:112262512-112314577 11 [Source:HGNC1.958193333 Symbol;Acc:HGNC:18156] 2.36651 ENSOCUG00000001041 MELK maternal embryonic1:17356593-17440708 leucine zipper kinase1.84243 [Source:HGNC 2.232573333 Symbol;Acc:HGNC:16870] ENSOCUG00000005948 DMXL2 Dmx-like 2 17:20907504-21083534[Source:HGNC Symbol;Acc:HGNC:2938]1.826606667 2.214373333 ENSOCUG00000023894 - Uncharacterized17:15188179-15592538 protein [Source:UniProtKB/TrEMBL;Acc:G1TZ16]1.881518 2.28827 ENSOCUG00000003319 HLA-DPA1 major histocompatibility12:23519394-23550367 complex,1.760171333 class II, DP alpha 1 2.156396667 [Source:HGNC Symbol;Acc:HGNC:4938] ENSOCUG00000015252 BBS12 Bardet-Biedl15:98580397-98582524 syndrome 12 [Source:HGNC1.984253333 Symbol;Acc:HGNC:26648] 2.46147 ENSOCUG00000011383 C4orf32 chromosome15:37251903-37252149 4 open reading frame 321.95721 [Source:HGNC Symbol;Acc:HGNC:26813] 2.42925 ENSOCUG00000009148 SERPINB8P1Oryctolagus9:103939905-103962577 cuniculus serpin peptidase1.88528 inhibitor, clade B8 (ovalbumin) 2.34808 pseudogene 1 (SERPINB8P1), mRNA. [Source:RefSeq mRNA;Acc:NM_001171285] ENSOCUG00000004027 TRAF3IP3 TRAF3 interacting16:62890878-62911114 protein 3 [Source:HGNC1.623813333 Symbol;Acc:HGNC:30766] 2.022646 ENSOCUG00000021174 - UncharacterizedGL018989:249305-253753 protein [Source:UniProtKB/TrEMBL;Acc:G1TXE2]1.716123333 2.137965333 ENSOCUG00000004941 ZNF852 zinc finger protein9:8249967-8268843 852 [Source:HGNC1.604713333 Symbol;Acc:HGNC:27713] 2.012943333

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ENSOCUG00000017539 SYK spleen tyrosine1:77228940-77325389 kinase [Source:HGNC1.843566667 Symbol;Acc:HGNC:11491] 2.31382 ENSOCUG00000006258 WDR72 WD repeat domain17:18835503-19069549 72 [Source:HGNC1.98726 Symbol;Acc:HGNC:26790] 2.514353333 ENSOCUG00000010775 CDKL5 cyclin-dependentX:4345275-4505068 kinase-like 5 [Source:HGNC1.973393333 Symbol;Acc:HGNC:11411] 2.50031 ENSOCUG00000024968 - 40S ribosomalGL018790:669552-670347 protein S3a [Source:UniProtKB/TrEMBL;Acc:G1TN72]1.631046667 2.072296667 ENSOCUG00000008075 ATP8B4 ATPase, class17:22339445-22605788 I, type 8B, member 41.659643 [Source:HGNC Symbol;Acc:HGNC:13536] 2.148496667 ENSOCUG00000006682 - GL018789:984158-9850631.572912667 2.046076667 ENSOCUG00000014516 CCDC68 coiled-coil domain9:95478203-95520929 containing 681.994516667 [Source:HGNC Symbol;Acc:HGNC:24350] 2.595246667 ENSOCUG00000022964 - 2:54877635-54878646 1.962935 2.555643333 ENSOCUG00000008522 LHX6 LIM homeoboxGL018699:5002268-5015445 6 [Source:HGNC1.761214667 Symbol;Acc:HGNC:21735] 2.297426667 ENSOCUG00000006720 FGD2 FYVE, RhoGEF12:26880658-26900345 and PH domain1.964300333 containing 2 [Source:HGNC 2.568653333 Symbol;Acc:HGNC:3664] ENSOCUG00000010148 - UncharacterizedGL018902:23470-29711 protein [Source:UniProtKB/TrEMBL;Acc:G1SYP3]1.724713333 2.25894 ENSOCUG00000012783 DAGLA diacylglycerolGL018717:3061606-3083158 lipase, alpha [Source:HGNC1.713603333 Symbol;Acc:HGNC:1165] 2.252546667 ENSOCUG00000013105 PLCG2 phospholipase5:36095028-36223534 C, gamma 2 (phosphatidylinositol-specific)1.964836667 [Source:HGNC 2.58285 Symbol;Acc:HGNC:9066] ENSOCUG00000014109 CDCA2 cell division2:44152053-44202114 cycle associated 2 1.570723333[Source:HGNC Symbol;Acc:HGNC:14623] 2.074523333 ENSOCUG00000025892 - UncharacterizedGL018806:131328-137311 protein [Source:UniProtKB/TrEMBL;Acc:G1TH84]1.777481667 2.365329667 ENSOCUG00000000547 SGOL2 shugoshin-like7:141167896-141191932 2 (S. pombe) [Source:HGNC1.671336667 Symbol;Acc:HGNC:30812] 2.229046667 ENSOCUG00000027535 PEG10 paternally expressed10:34277350-34356993 10 [Source:HGNC1.93218 Symbol;Acc:HGNC:14005] 2.588683333 ENSOCUG00000014255 DUOX2 dual oxidase17:27374401-27444343 2 [Source:HGNC Symbol;Acc:HGNC:13273]1.725205333 2.314516667 ENSOCUG00000014936 - 14:30605219-30606457 1.75659 2.365573333 ENSOCUG00000003656 CDH2 Uncharacterized9:69300656-69515427 protein [Source:UniProtKB/TrEMBL;Acc:G1TPS9]1.683873333 2.271343333 ENSOCUG00000025069 - Histone H2A12:11020426-11020819 [Source:UniProtKB/TrEMBL;Acc:G1U2Q4]1.903891667 2.578356667 ENSOCUG00000024656 NCX1 Uncharacterized2:146047032-146122709 protein [Source:UniProtKB/TrEMBL;Acc:G1U740]1.96932 2.66815 ENSOCUG00000012699 FYB FYNDraft binding11:60148037-60240706 protein [Source:HGNC1.791023667 Symbol;Acc:HGNC:4036] 2.4325 ENSOCUG00000016491 KIF14 kinesin family16:70759334-70830022 member 14 [Source:HGNC1.95574 Symbol;Acc:HGNC:19181] 2.658486667 ENSOCUG00000017719 NEK5 NIMA-relatedGL018705:5787044-5899032 kinase 5 [Source:HGNC1.87061 Symbol;Acc:HGNC:7748] 2.55597 ENSOCUG00000029283 ZNF484 Uncharacterized1:70029261-70031400 protein [Source:UniProtKB/TrEMBL;Acc:U3KLY2]1.964193333 2.685123333 ENSOCUG00000000436 - UncharacterizedGL018782:409127-424391 protein [Source:UniProtKB/TrEMBL;Acc:G1SDA3]1.623165333 2.229139 ENSOCUG00000026148 KBTBD8 kelch repeat9:34217719-34228653 and BTB (POZ) domain1.697836667 containing 8 [Source:HGNC 2.344276667 Symbol;Acc:HGNC:30691] ENSOCUG00000008174 STAMBPL1 STAM binding18:36796857-36840581 protein-like 1 [Source:HGNC1.99713 Symbol;Acc:HGNC:24105] 2.772866667 ENSOCUG00000027052 - UncharacterizedGL018752:1823400-1833875 protein [Source:UniProtKB/TrEMBL;Acc:G1TVA1]1.735913333 2.416443333 ENSOCUG00000009580 WNT10B wingless-type4:33265516-33280776 MMTV integration1.698615333 site family, member 10B 2.36553[Source:HGNC Symbol;Acc:HGNC:12775] ENSOCUG00000000121 LRR1 leucine rich 17:68756996-68769661repeat protein 1 [Source:HGNC1.94109 Symbol;Acc:HGNC:19742] 2.71305 ENSOCUG00000011054 PIK3CD phosphatidylinositol-4,5-bisphosphate13:140429867-1405486171.740573333 3-kinase, catalytic 2.434047667 subunit delta [Source:HGNC Symbol;Acc:HGNC:8977] ENSOCUG00000016477 SELP selectin P (granule13:21725620-21768081 membrane protein1.697575333 140kDa, antigen CD62) 2.37622 [Source:HGNC Symbol;Acc:HGNC:10721] ENSOCUG00000026180 XKR8 XK, Kell blood13:137530369-137536734 group complex subunit-related1.52324 family, 2.134616667member 8 [Source:HGNC Symbol;Acc:HGNC:25508] ENSOCUG00000001906 HRH1 histamine receptor9:12523428-12524895 H1 [Source:HGNC1.83964 Symbol;Acc:HGNC:5182] 2.581376667 ENSOCUG00000001304 AGAP2 ArfGAP withGL018714:831954-941468 GTPase domain, ankyrin1.86485 repeat and PH 2.648243333domain 2 [Source:HGNC Symbol;Acc:HGNC:16921] ENSOCUG00000004485 E2F8 E2F transcription1:158155123-158171097 factor 8 [Source:HGNC1.925683333 Symbol;Acc:HGNC:24727] 2.742383333 ENSOCUG00000004162 PRRT3 proline-rich GL018802:270517-278532transmembrane protein1.573516667 3 [Source:HGNC Symbol;Acc:HGNC:26591] 2.2414 ENSOCUG00000012557 SOX6 SRY (sex determiningGL018733:60436-594016 region Y)-box1.483994333 6 [Source:HGNC 2.114926667 Symbol;Acc:HGNC:16421] ENSOCUG00000022315 KIAA1199 cell migrationGL018737:1821099-1888687 inducing protein,1.812793333 hyaluronan binding [Source:HGNC 2.588753333 Symbol;Acc:HGNC:29213] ENSOCUG00000010078 GPER1 G protein-coupledGL019453:43358-44483 estrogen receptor1.694896667 1 [Source:HGNC Symbol;Acc:HGNC:4485] 2.42075 ENSOCUG00000000528 TCF15 transcription4:8193969-8198417 factor 15 (basic helix-loop-helix)1.75927 [Source:HGNC 2.515316667 Symbol;Acc:HGNC:11627] ENSOCUG00000029622 - Uncharacterized13:35714065-35746533 protein [Source:UniProtKB/TrEMBL;Acc:U3KM10]1.848846667 2.646743333 ENSOCUG00000026015 - Uncharacterized5:22586306-22596405 protein [Source:UniProtKB/TrEMBL;Acc:G1SN51]1.914563333 2.744716667 ENSOCUG00000012739 PIK3CG phosphatidylinositol-4,5-bisphosphate7:43349461-433849971.758716667 3-kinase, catalytic 2.533983333 subunit gamma [Source:HGNC Symbol;Acc:HGNC:8978] ENSOCUG00000024118 CDT1 chromatin licensingGL019360:45840-48784 and DNA replication1.61473 factor 1 [Source:HGNC 2.3374 Symbol;Acc:HGNC:24576] ENSOCUG00000025837 NFAM1 NFAT activatingGL018734:186486-214798 protein with ITAM1.686166667 motif 1 [Source:HGNC 2.441779667 Symbol;Acc:HGNC:29872] ENSOCUG00000001366 - Uncharacterized7:108621605-108641977 protein [Source:UniProtKB/TrEMBL;Acc:G1SFA0]1.456276 2.110396667 ENSOCUG00000005507 GNA14 guanine nucleotide1:63848019-64070836 binding protein (G1.41317 protein), alpha 14 2.052763333 [Source:HGNC Symbol;Acc:HGNC:4382]

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ENSOCUG00000021352 - UncharacterizedGL018724:2793160-2814295 protein [Source:UniProtKB/TrEMBL;Acc:G1U598]1.580506667 2.29982 ENSOCUG00000015410 NDC80 NDC80 kinetochore9:59439910-59522894 complex component1.424253333 [Source:HGNC 2.075876667 Symbol;Acc:HGNC:16909] ENSOCUG00000003325 SOWAHC sosondowah2:83058560-83060299 ankyrin repeat domain family1.64339 member C [Source:HGNC 2.398246667 Symbol;Acc:HGNC:26149] ENSOCUG00000026297 NXPH2 neurexophilin7:76530826-76655673 2 [Source:HGNC1.734313333 Symbol;Acc:HGNC:8076] 2.532136667 ENSOCUG00000001933 PTPRJ protein tyrosine1:187290553-187417474 phosphatase, receptor1.425153333 type, J [Source:HGNC 2.085213333 Symbol;Acc:HGNC:9673] ENSOCUG00000010020 DNAJC6 DnaJ (Hsp40)13:100963486-101144759 homolog, subfamily1.964823333 C, member 6 [Source:HGNC 2.877396667 Symbol;Acc:HGNC:15469] ENSOCUG00000009729 RNF43 ring finger protein19:29850149-29914840 43 [Source:HGNC1.903423333 Symbol;Acc:HGNC:18505] 2.795926667 ENSOCUG00000010144 TTC22 tetratricopeptide13:112126803-112145762 repeat domain 1.66657333322 [Source:HGNC Symbol;Acc:HGNC:26067] 2.470151 ENSOCUG00000022067 DLX4 distal-less homeobox19:37670258-37675009 4 [Source:HGNC1.767885667 Symbol;Acc:HGNC:2917] 2.649450667 ENSOCUG00000004077 SLC4A11 solute carrier4:10162606-10173558 family 4, sodium borate1.97041 transporter, member 2.959176667 11 [Source:HGNC Symbol;Acc:HGNC:16438] ENSOCUG00000000699 CENPE centromere protein15:46423571-46506024 E, 312kDa [Source:HGNC1.402413333 Symbol;Acc:HGNC:1856] 2.11086 ENSOCUG00000021348 ZNF771 zinc finger proteinGL018763:1505977-1506796 771 [Source:HGNC1.534803333 Symbol;Acc:HGNC:29653] 2.312306667 ENSOCUG00000006792 NCAPG non-SMC condensin2:8357628-8403499 I complex, subunit1.89015 G [Source:HGNC 2.855356667 Symbol;Acc:HGNC:24304] ENSOCUG00000004450 CCNF cyclin F [Source:HGNCGL018968:175823-194547 Symbol;Acc:HGNC:1591]1.36318 2.063706667 ENSOCUG00000029391 ZNF668 GL018752:1226884-12301711.93849 2.93985 ENSOCUG00000011299 CHEK2 checkpoint kinaseGL018723:1963190-2010558 2 [Source:HGNC1.368686667 Symbol;Acc:HGNC:16627] 2.079073333 ENSOCUG00000009143 CCNE1 cyclin E1 [Source:HGNCGL018722:608864-621359 Symbol;Acc:HGNC:1589]1.628930667 2.47792 ENSOCUG00000006806 ZWINT ZW10 interacting18:29718349-29721825 kinetochore protein1.37674 [Source:HGNC 2.098016667Symbol;Acc:HGNC:13195] ENSOCUG00000006954 PRF1 perforin 1 (pore18:16429934-16435034 forming protein)1.392940333 [Source:HGNC Symbol;Acc:HGNC:9360] 2.1247638 ENSOCUG00000011694 HECW2 HECT, C2 and7:136627879-136803253 WW domain containing1.853886667 E3 ubiquitin protein 2.829153333 ligase 2 [Source:HGNC Symbol;Acc:HGNC:29853] ENSOCUG00000022021 IL22RA2 interleukin 2212:127564879-127578436 receptor, alpha 2 1.433616667[Source:HGNC Symbol;Acc:HGNC:14901] 2.191200333 ENSOCUG00000027916 FZD5 frizzled class7:148646755-148648516 receptor 5 [Source:HGNC1.868406667 Symbol;Acc:HGNC:4043] 2.86084 ENSOCUG00000015382 MAB21L3 mab-21-likeDraft13:48145204-48166813 3 (C. elegans) [Source:HGNC1.823203333 Symbol;Acc:HGNC:26787] 2.794033333 ENSOCUG00000013471 LIPG lipase, endothelial9:90453684-90473093 [Source:HGNC1.595716667 Symbol;Acc:HGNC:6623] 2.449046667 ENSOCUG00000006436 - Uncharacterized7:7973608-7974289 protein [Source:UniProtKB/TrEMBL;Acc:G1SR02]1.580766333 2.430946667 ENSOCUG00000021020 KDM8 lysine (K)-specific6:17405711-17443652 demethylase1.809826667 8 [Source:HGNC Symbol;Acc:HGNC:25840] 2.789063333 ENSOCUG00000011957 AURKB aurora kinase19:11052806-11058032 B [Source:HGNC1.884393333 Symbol;Acc:HGNC:11390] 2.936153333 ENSOCUG00000017771 BMX BMX non-receptorX:1339703-1392524 tyrosine kinase1.520502667 [Source:HGNC Symbol;Acc:HGNC:1079] 2.37085 ENSOCUG00000002510 SNCB synuclein, beta3:57099231-57346656 [Source:HGNC 1.898353333Symbol;Acc:HGNC:11140] 2.964493333 ENSOCUG00000008255 CENPM centromere proteinGL018734:619866-633930 M [Source:HGNC1.420224333 Symbol;Acc:HGNC:18352] 2.221293333 ENSOCUG00000027480 - UncharacterizedAAGW02083478:1233-5107 protein [Source:UniProtKB/TrEMBL;Acc:G1TX71]1.69222 2.674317333 ENSOCUG00000015756 CASC5 cancer susceptibility17:31375804-31453375 candidate 5 [Source:HGNC1.344683 Symbol;Acc:HGNC:24054] 2.159333333 ENSOCUG00000014008 CHAF1B chromatin assemblyGL018727:573511-598950 factor 1, subunit1.660576667 B (p60) [Source:HGNC 2.683563333 Symbol;Acc:HGNC:1911] ENSOCUG00000021564 - UncharacterizedGL018704:4851547-4854283 protein [Source:UniProtKB/TrEMBL;Acc:G1TZN5]1.315353333 2.131116667 ENSOCUG00000003606 KIF21B kinesin family16:70396857-70440419 member 21B [Source:HGNC1.534061 Symbol;Acc:HGNC:29442] 2.489773333 ENSOCUG00000023797 - Uncharacterized13:126975129-127002162 protein [Source:UniProtKB/TrEMBL;Acc:G1TKY8]1.5455 2.517083333 ENSOCUG00000010075 TRABD2A TraB domain2:101312110-101403398 containing 2A [Source:HGNC1.302249667 Symbol;Acc:HGNC:27013] 2.132636667 ENSOCUG00000024415 - 60S ribosomal3:81763132-81763768 protein L13 [Source:UniProtKB/TrEMBL;Acc:G1TPV0]1.640428 2.728886667 ENSOCUG00000014866 HEPH hephaestin [Source:HGNCX:44731287-44817736 Symbol;Acc:HGNC:4866]1.461666667 2.47022 ENSOCUG00000022391 - Uncharacterized10:21473873-21534045 protein [Source:UniProtKB/TrEMBL;Acc:G1TLH3]1.36099 2.323061 ENSOCUG00000023219 ASPG asparaginaseGL018751:20-13884 [Source:HGNC Symbol;Acc:HGNC:20123]1.376586667 2.352026 ENSOCUG00000006383 GHRL ghrelin/obestatinGL018802:33235-36519 prepropeptide 1.530533333[Source:HGNC Symbol;Acc:HGNC:18129] 2.630573333 ENSOCUG00000023214 P2RY11 purinergic receptorGL018833:204746-205433 P2Y, G-protein1.592063333 coupled, 11 [Source:HGNC 2.747746667 Symbol;Acc:HGNC:8540] ENSOCUG00000000574 PLEKHH1 pleckstrin homology20:4656675-4722365 domain containing,1.184193333 family H (with MyTH4 2.06347 domain) member 1 [Source:HGNC Symbol;Acc:HGNC:17733] ENSOCUG00000010412 - 7:162713368-1627138861.374603333 2.419471 ENSOCUG00000009079 MATN4 matrilin 4 [Source:HGNCGL018725:449338-456362 Symbol;Acc:HGNC:6910]1.160174333 2.047083333 ENSOCUG00000024221 INMT indolethylamine10:15063667-15071335 N-methyltransferase1.492246667 [Source:RefSeq 2.678473333peptide;Acc:NP_001075512] ENSOCUG00000028503 SCARNA6 Small Cajal GL018736:750881-793567body specific RNA1.242883333 6 [Source:RFAM;Acc:RF00478] 2.26955 ENSOCUG00000020988 ANGPTL6 angiopoietin-likeGL018833:217265-222379 6 [Source:HGNC1.167913333 Symbol;Acc:HGNC:23140] 2.14669 ENSOCUG00000027953 - Histone H2B12:10804468-10804849 [Source:UniProtKB/TrEMBL;Acc:G1TP83]1.188574667 2.199893333

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ENSOCUG00000009751 HCK HCK proto-oncogene,4:7202138-7244423 Src family tyrosine1.505083 kinase [Source:HGNC 2.819153 Symbol;Acc:HGNC:4840] ENSOCUG00000005976 - UncharacterizedGL018806:141966-150715 protein [Source:UniProtKB/TrEMBL;Acc:G1SQ20]1.177090667 2.208276 ENSOCUG00000011446 LHFPL5 lipoma HMGIC12:25832601-25851976 fusion partner-like1.241106333 5 [Source:HGNC Symbol;Acc:HGNC:21253] 2.32966 ENSOCUG00000002020 LGI3 leucine-richGL018798:518404-525543 repeat LGI family, 1.286196667member 3 [Source:HGNC Symbol;Acc:HGNC:18711] 2.41606 ENSOCUG00000023227 - Uncharacterized15:24324998-24325406 protein [Source:UniProtKB/TrEMBL;Acc:G1TUN8]1.150374667 2.162853333 ENSOCUG00000010754 NIPA1 non imprinted17:77594631-77757611 in Prader-Willi/Angelman1.237428667 syndrome 1 [Source:HGNC 2.3435 Symbol;Acc:HGNC:17043] ENSOCUG00000021982 - Uncharacterized13:72231926-72233513 protein [Source:UniProtKB/TrEMBL;Acc:G1TSW3]1.104136 2.094323333 ENSOCUG00000009872 TMEM178Atransmembrane2:146569786-146636719 protein 178A [Source:HGNC1.105146 Symbol;Acc:HGNC:28517] 2.106333333 ENSOCUG00000015935 TCF7 transcription3:16946023-16971140 factor 7 (T-cell specific,1.180053333 HMG-box) [Source:HGNC 2.252643667 Symbol;Acc:HGNC:11639] ENSOCUG00000022454 FOXE1 forkhead box1:15222386-15225698 E1 (thyroid transcription1.245960667 factor 2) [Source:HGNC 2.39084 Symbol;Acc:HGNC:3806] ENSOCUG00000001351 CD96 CD96 molecule14:107561761-107670086 [Source:HGNC Symbol;Acc:HGNC:16892]1.2781401 2.472095333 ENSOCUG00000002794 ZNF618 zinc finger proteinGL018699:13530451-13602936 618 [Source:HGNC1.286974 Symbol;Acc:HGNC:29416] 2.49089 ENSOCUG00000015037 UGT8 UDP glycosyltransferase15:34780876-34880756 8 [Source:HGNC1.312493 Symbol;Acc:HGNC:12555] 2.552846667 ENSOCUG00000017070 P2RY4 pyrimidinergicX:48814660-48815758 receptor P2Y, G-protein1.096158 coupled, 4 [Source:HGNC 2.149730667 Symbol;Acc:HGNC:8542] ENSOCUG00000002661 - Uncharacterized12:104750735-104836786 protein [Source:UniProtKB/TrEMBL;Acc:G1SI11]1.505538433 2.961990333 ENSOCUG00000007928 APOM apolipoprotein12:20467683-20469540 M [Source:HGNC Symbol;Acc:HGNC:13916]1.043916 2.07522 ENSOCUG00000016173 WNT2 Oryctolagus7:27896340-27944312 cuniculus wingless-type1.145591 MMTV integration 2.456020667 site family member 2 (WNT2), mRNA. [Source:RefSeq mRNA;Acc:NM_001171042] ENSOCUG00000015611 SCUBE3 signal peptide,12:25322822-25342079 CUB domain, EGF-like1.124546333 3 [Source:HGNC 2.449663333 Symbol;Acc:HGNC:13655] ENSOCUG00000011287 - Uncharacterized4:72713745-72715030 protein [Source:UniProtKB/TrEMBL;Acc:G1T107]1.267438 2.80013 ENSOCUG00000017125 GPR19 G protein-coupled8:27073127-27074375 receptor 19 [Source:HGNC1.270506667 Symbol;Acc:HGNC:4473] 2.819016667 ENSOCUG00000016862 SHH sonic hedgehog13:11519668-11532132 [Source:HGNC1.069206667 Symbol;Acc:HGNC:10848] 2.61601 ENSOCUG00000006095 GLB1L2 galactosidase,GL018742:964762-1006772 beta 1-like 2 [Source:HGNC1.000369 Symbol;Acc:HGNC:25129] 2.463367667 ENSOCUG00000021306 HIST1H2AE Draft12:11012381-11012774 1.07994 2.726696667 ENSOCUG00000010806 AP1S3 adaptor-related7:165265210-165281080 protein complex1.001401667 1, sigma 3 subunit [Source:HGNC 2.94855 Symbol;Acc:HGNC:18971] ENSOCUG00000018093 U5 U5 spliceosomalGL018739:2144465-2144582 RNA [Source:RFAM;Acc:RF00020]94.259 240.57 ENSOCUG00000002612 KRT84 keratin 84 [Source:HGNC4:36443351-36449519 Symbol;Acc:HGNC:6461]14.36623333 30.1767 ENSOCUG00000013134 ST8SIA1 ST8 alpha-N-acetyl-neuraminide8:17831289-179718716.973943333 alpha-2,8-sialyltransferase 12.61317333 1 [Source:HGNC Symbol;Acc:HGNC:10869] ENSOCUG00000027708 U1 U1 spliceosomal17:54352863-54353027 RNA [Source:RFAM;Acc:RF00003]6.006766667 12.0019 ENSOCUG00000006831 GNG4 guanine nucleotide16:32642972-32673390 binding protein3.995823333 (G protein), gamma 14.35868667 4 [Source:HGNC Symbol;Acc:HGNC:4407] ENSOCUG00000016227 SVEP1 sushi, von Willebrand1:2642081-2858206 factor type A,12.93697 EGF and pentraxin 25.08766667 domain containing 1 [Source:HGNC Symbol;Acc:HGNC:15985] ENSOCUG00000008528 - Uncharacterized19:42089644-42090579 protein [Source:UniProtKB/TrEMBL;Acc:G1SVC1]12.44433333 25.8798 ENSOCUG00000022283 DCUN1D3 DCN1, defective6:11740941-11814124 in cullin neddylation5.867193333 1, domain containing 10.16083333 3 [Source:HGNC Symbol;Acc:HGNC:28734] ENSOCUG00000021137 SFRP5 secreted frizzled-related18:45921311-45925049 protein5.932106667 5 [Source:HGNC Symbol;Acc:HGNC:10779] 10.63611667 ENSOCUG00000008647 S100A3 S100 calcium13:38908337-38910127 binding protein A386.49603333 [Source:HGNC Symbol;Acc:HGNC:10493] 192.172 ENSOCUG00000029367 C1QA complement13:130489830-130493886 component 1, q subcomponent,12.78452667 A chain [Source:HGNC 24.19966667 Symbol;Acc:HGNC:1241] ENSOCUG00000002203 PTN pleiotrophin7:1421173-1528811 [Source:HGNC Symbol;Acc:HGNC:9630]12.79536 24.4085 ENSOCUG00000026465 BTNL9 butyrophilin-like11:31685495-31726198 9 [Source:HGNC12.84696667 Symbol;Acc:HGNC:24176] 24.91473333 ENSOCUG00000007366 ENDOU endonuclease,8:42324-50629 polyU-specific [Source:HGNC12.24523333 Symbol;Acc:HGNC:14369] 24.39976667 ENSOCUG00000011380 CIDEA cell death-inducing9:49844991-49871219 DFFA-like 12.16893333effector a [Source:HGNC 24.81196667 Symbol;Acc:HGNC:1976] ENSOCUG00000015143 - 13:130475112-13048171611.85092333 23.26806667 ENSOCUG00000011686 - solute carrier9:17681396-17686612 family 38, member11.05005333 3 [Source:HGNC Symbol;Acc:HGNC:18044] 23.53626667 ENSOCUG00000012871 CDNF cerebral dopamine16:46343501-46364239 neurotrophic1.875466667 factor [Source:HGNC 1.039599333Symbol;Acc:HGNC:24913] ENSOCUG00000022728 - UncharacterizedGL018709:2237386-2237928 protein [Source:UniProtKB/TrEMBL;Acc:G1TFA7]1.755956667 1.004676333 ENSOCUG00000015966 - GL018710:3037745-37235741.896828667 1.108823667 ENSOCUG00000027809 - Uncharacterized13:60558376-60565688 protein [Source:UniProtKB/TrEMBL;Acc:G1TYA3]1.840848667 1.093688333 ENSOCUG00000013668 - Uncharacterized1:11742784-12077819 protein [Source:UniProtKB/TrEMBL;Acc:G1T5W1]1.68368 1.028569333 ENSOCUG00000017762 - 7:158586368-1585870091.597009333 1.020511333 ENSOCUG00000022800 C5orf52 chromosome21:3222516-3230768 5 open reading frame 521.90118 [Source:HGNC 1.218157667Symbol;Acc:HGNC:35121] ENSOCUG00000003033 GDNF glial cell derived11:58822683-58824327 neurotrophic factor1.562350667 [Source:HGNC Symbol;Acc:HGNC:4232] 1.006111 ENSOCUG00000003724 MEGF10 multiple EGF-like-domains3:11015809-11141734 10 [Source:HGNC1.891346667 Symbol;Acc:HGNC:29634] 1.224504667

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ENSOCUG00000015838 COL9A2 collagen, type13:126185291-126198465 IX, alpha 2 [Source:HGNC1.642273333 Symbol;Acc:HGNC:2218] 1.063896667 ENSOCUG00000013331 - Glutathione X:61956587-61957025peroxidase [Source:UniProtKB/TrEMBL;Acc:G1T569]1.94693 1.266960667 ENSOCUG00000015454 AGBL1 ATP/GTP bindingGL018797:11709-648334 protein-like 11.567169667 [Source:HGNC Symbol;Acc:HGNC:26504] 1.039077667 ENSOCUG00000002903 ST8SIA2 ST8 alpha-N-acetyl-neuraminideGL018759:360790-378898 alpha-2,8-sialyltransferase1.98966 1.348098333 2 [Source:HGNC Symbol;Acc:HGNC:10870] ENSOCUG00000022375 CRYGS Oryctolagus14:79044655-79050044 cuniculus crystallin, gamma1.86267 S (CRYGS), 1.272636667mRNA. [Source:RefSeq mRNA;Acc:NM_001099960] ENSOCUG00000008298 FAXC failed axon connections12:86915147-87016975 homolog1.554619667 (Drosophila) [Source:HGNC 1.068041667 Symbol;Acc:HGNC:20742] ENSOCUG00000024121 CABYR calcium binding9:65300875-65324545 tyrosine-(Y)-phosphorylation1.5498 regulated 1.068086667 [Source:HGNC Symbol;Acc:HGNC:15569] ENSOCUG00000012952 - Uncharacterized13:24452525-24456240 protein [Source:UniProtKB/TrEMBL;Acc:G1T4F1]1.517684667 1.051259 ENSOCUG00000027366 WAC UncharacterizedGL018707:5345731-5421622 protein [Source:UniProtKB/TrEMBL;Acc:G1TWW4]1.502686667 1.051390333 ENSOCUG00000016341 RAB37 RAB37, memberGL018989:160456-165972 RAS oncogene family1.50327 [Source:HGNC 1.066223333 Symbol;Acc:HGNC:30268] ENSOCUG00000024604 - Uncharacterized4:53489960-53491208 protein [Source:UniProtKB/TrEMBL;Acc:G1U3W7]1.816143767 1.290131 ENSOCUG00000027207 FANCE Fanconi anemia,12:25523150-25542984 complementation1.987136667 group E [Source:HGNC 1.411923333 Symbol;Acc:HGNC:3586] ENSOCUG00000027691 - Uncharacterized4:36851075-36854226 protein [Source:UniProtKB/TrEMBL;Acc:G1U758]1.475090667 1.053766 ENSOCUG00000014768 NRCAM neuronal cell7:44716023-44969835 adhesion molecule1.534273333 [Source:HGNC Symbol;Acc:HGNC:7994] 1.100664667 ENSOCUG00000016324 CIT citron rho-interacting21:12685145-12862437 serine/threonine1.919873333 kinase [Source:HGNC 1.377306667 Symbol;Acc:HGNC:1985] ENSOCUG00000006107 GRAMD2 GRAM domain17:340305-349951 containing 2 [Source:HGNC1.396295333 Symbol;Acc:HGNC:27287] 1.001789667 ENSOCUG00000016450 NTF3 neurotrophin8:31528590-31600789 3 [Source:HGNC Symbol;Acc:HGNC:8023]1.88259 1.351855333 ENSOCUG00000011599 CACNA1C calcium channel,8:35013638-35240262 voltage-dependent,1.75896 L type, alpha 1C 1.263952667subunit [Source:HGNC Symbol;Acc:HGNC:1390] ENSOCUG00000025713 ASGR1 asialoglycoprotein19:11951787-11954271 receptor 1 [Source:HGNC1.893463333 Symbol;Acc:HGNC:742] 1.364566667 ENSOCUG00000007204 SLC39A5 solute carrier4:39793739-39825896 family 39 (zinc transporter),1.91009 member 5 [Source:HGNC 1.377426667 Symbol;Acc:HGNC:20502] ENSOCUG00000014561 CDH20 cadherin 20,9:101780306-101895214 type 2 [Source:HGNC1.939686667 Symbol;Acc:HGNC:1760] 1.402016667 ENSOCUG00000023917 EBF4 early B-cell 4:9574724-9787529factor 4 [Source:HGNC1.979113333 Symbol;Acc:HGNC:29278] 1.45335 ENSOCUG00000022301 SLC37A1 soluteDraft carrierGL019109:79667-123539 family 37 (glucose-6-phosphate1.763036667 transporter), 1.295517667 member 1 [Source:HGNC Symbol;Acc:HGNC:11024] ENSOCUG00000023860 ADRA2B adrenoceptor2:95178153-95179335 alpha 2B [Source:HGNC1.914973333 Symbol;Acc:HGNC:282] 1.412356333 ENSOCUG00000010801 PPEF1 protein phosphatase,X:4536499-4645500 EF-hand calcium1.891703333 binding domain 1 [Source:HGNC 1.40221 Symbol;Acc:HGNC:9243] ENSOCUG00000005785 BAI2 brain-specificGL018704:6391779-6421030 angiogenesis inhibitor1.777016667 2 [Source:HGNC 1.317364667Symbol;Acc:HGNC:944] ENSOCUG00000005993 - UncharacterizedGL018831:215949-218458 protein [Source:UniProtKB/TrEMBL;Acc:G1SQ33]1.599891667 1.190124333 ENSOCUG00000003044 SPA17 Oryctolagus1:92552343-92565075 cuniculus sperm autoantigenic1.66152 protein 17 (SPA17), 1.245673 mRNA. [Source:RefSeq mRNA;Acc:NM_001082626] ENSOCUG00000024851 DOC2B double C2-like19:16796154-16809576 domains, beta [Source:HGNC1.379916667 Symbol;Acc:HGNC:2986] 1.040501 ENSOCUG00000009667 GABRE gamma-aminobutyricGL018731:714120-733055 acid (GABA)1.642746667 A receptor, epsilon 1.240084333 [Source:HGNC Symbol;Acc:HGNC:4085] ENSOCUG00000016937 PDZD3 PDZ domainGL018823:648829-652123 containing 3 [Source:HGNC1.505362667 Symbol;Acc:HGNC:19891] 1.136387333 ENSOCUG00000029194 KRT3 Keratin, type4:36733701-36739307 II cytoskeletal 3 [Source:UniProtKB/Swiss-Prot;Acc:Q29426]1.628387 1.230174 ENSOCUG00000029334 - UncharacterizedGL018731:2073007-2076005 protein [Source:UniProtKB/TrEMBL;Acc:G1TV96]1.485906667 1.123929333 ENSOCUG00000003273 GPIIB Oryctolagus19:44648319-44660521 cuniculus glycoprotein1.884293333 IIb (GPIIB), mRNA. [Source:RefSeq 1.43532 mRNA;Acc:NM_001082065] ENSOCUG00000021330 - chromosomeGL018717:180187-183926 11 open reading frame1.792933333 95 [Source:HGNC 1.368993667 Symbol;Acc:HGNC:28449] ENSOCUG00000017803 - UncharacterizedGL018999:5725-30429 protein [Source:UniProtKB/TrEMBL;Acc:G1TEG6]1.51071 1.157155667 ENSOCUG00000004997 MST1 macrophage9:17191707-17204240 stimulating 1 (hepatocyte1.68629 growth factor-like) 1.292186667 [Source:HGNC Symbol;Acc:HGNC:7380] ENSOCUG00000004155 ACOX2 Oryctolagus9:25266408-25291424 cuniculus acyl-CoA1.447036667 oxidase 2, branched chain 1.109627667 (ACOX2), mRNA. [Source:RefSeq mRNA;Acc:NM_001082763] ENSOCUG00000029704 - Uncharacterized9:3603739-3925918 protein [Source:UniProtKB/TrEMBL;Acc:U3KPG1]1.65746 1.272715 ENSOCUG00000004594 MND1 meiotic nuclear15:9545675-9635691 divisions 1 homolog1.804341 (S. cerevisiae) [Source:HGNC 1.38907 Symbol;Acc:HGNC:24839] ENSOCUG00000025849 TEX29 testis expressedGL019372:1956-29189 29 [Source:HGNC 1.679752Symbol;Acc:HGNC:20370] 1.294285667 ENSOCUG00000004441 PBLD phenazine biosynthesis-like18:18330015-18354134 protein1.837673333 domain containing [Source:HGNC 1.41802 Symbol;Acc:HGNC:23301] ENSOCUG00000028095 - Uncharacterized12:59449807-59450095 protein [Source:UniProtKB/TrEMBL;Acc:G1TLD8]1.593034667 1.230398 ENSOCUG00000023544 - UncharacterizedGL018991:245919-247023 protein [Source:UniProtKB/TrEMBL;Acc:G1TN87]1.394068667 1.076866667 ENSOCUG00000024498 - Uncharacterized13:52488775-52585811 protein [Source:UniProtKB/TrEMBL;Acc:G1TI26]1.327180333 1.028714 ENSOCUG00000007717 IL2RB interleukin 2GL018973:218-70051 receptor, beta [Source:HGNC1.749690333 Symbol;Acc:HGNC:6009] 1.356434667 ENSOCUG00000002982 MYRFL myelin regulatory4:48906544-48983260 factor-like [Source:HGNC1.744876667 Symbol;Acc:HGNC:26316] 1.355623333 ENSOCUG00000029750 - UncharacterizedGL019624:150-1911 protein [Source:UniProtKB/TrEMBL;Acc:U3KMV8]1.561436667 1.217280667 ENSOCUG00000021776 POU2F2 POU class 2GL018789:11379-47075 homeobox 2 [Source:HGNC1.579729667 Symbol;Acc:HGNC:9213] 1.231807333 ENSOCUG00000025997 HAUS8 HAUS augmin-likeGL018776:1142933-1150494 complex, subunit1.51404 8 [Source:HGNC 1.182116667 Symbol;Acc:HGNC:30532]

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ENSOCUG00000014235 GALNT9 polypeptide GL018821:36649-76447N-acetylgalactosaminyltransferase1.30083 9 [Source:HGNC 1.018289667 Symbol;Acc:HGNC:4131] ENSOCUG00000013397 RPL23A UncharacterizedGL018706:4280577-4414541 protein [Source:UniProtKB/TrEMBL;Acc:G1SE76]1.451859333 1.137510333 ENSOCUG00000003665 CCR5 Oryctolagus9:14560703-14561762 cuniculus chemokine1.397687333 (C-C motif) receptor 1.095179333 5 (CCR5), mRNA. [Source:RefSeq mRNA;Acc:NM_001171125] ENSOCUG00000022648 - Uncharacterized9:43402437-43402743 protein [Source:UniProtKB/TrEMBL;Acc:G1TYD7]1.39908 1.096987333 ENSOCUG00000027361 - Uncharacterized18:5214918-5215290 protein [Source:UniProtKB/TrEMBL;Acc:G1U544]1.751054667 1.37495 ENSOCUG00000007165 ISLR2 immunoglobulinGL019108:1683-85767 superfamily containing1.635706667 leucine-rich repeat 1.287178333 2 [Source:HGNC Symbol;Acc:HGNC:29286] ENSOCUG00000025408 - UncharacterizedAAGW02081905:3334-8018 protein [Source:UniProtKB/TrEMBL;Acc:G1TJN3]1.568634667 1.237609 ENSOCUG00000007425 CADPS2 Ca++-dependent7:21978279-22440132 secretion activator1.533596667 2 [Source:HGNC 1.210673333Symbol;Acc:HGNC:16018] ENSOCUG00000023484 HHIPL1 HHIP-like 1GL018761:35305-56304 [Source:HGNC Symbol;Acc:HGNC:19710]1.39895 1.106772333 ENSOCUG00000025569 CCR7 chemokine (C-C19:41675422-41685281 motif) receptor 7 [Source:HGNC1.774905 Symbol;Acc:HGNC:1608] 1.404659 ENSOCUG00000007453 SMAD9 SMAD familyGL018702:7770208-7838621 member 9 [Source:HGNC1.299726667 Symbol;Acc:HGNC:6774] 1.033378 ENSOCUG00000006702 GPR37 G protein-coupled7:19794606-19820536 receptor 37 (endothelin1.297145333 receptor type B-like) 1.03746 [Source:HGNC Symbol;Acc:HGNC:4494] ENSOCUG00000022131 - GL018765:148651-1963371.51129 1.215440667 ENSOCUG00000017394 SCNN1G sodium channel,6:14008263-14035635 non-voltage-gated 1,1.84429 gamma subunit [Source:HGNC 1.488233333 Symbol;Acc:HGNC:10602] ENSOCUG00000016911 TDRD12 tudor domain5:2736728-2847865 containing 12 [Source:HGNC1.549726667 Symbol;Acc:HGNC:25044] 1.250633333 ENSOCUG00000021238 - UncharacterizedGL018980:89298-93070 protein [Source:UniProtKB/TrEMBL;Acc:G1TGT6]1.479643333 1.19479 ENSOCUG00000017128 NMU Neuromedin-U-2515:93200548-93225372 [Source:UniProtKB/Swiss-Prot;Acc:P34965]1.766536667 1.429456667 ENSOCUG00000002909 GRB14 growth factor7:103859664-103986957 receptor-bound protein1.926763333 14 [Source:HGNC 1.566033333 Symbol;Acc:HGNC:4565] ENSOCUG00000000945 SRSF12 serine/arginine-rich12:75957740-75980257 splicing factor1.679433333 12 [Source:HGNC Symbol;Acc:HGNC:21220] 1.36564 ENSOCUG00000015552 PLXNA4 plexin A4 [Source:HGNC7:10622321-11050449 Symbol;Acc:HGNC:9102]1.82562 1.488053333 ENSOCUG00000025473 MMP17 matrix metallopeptidaseGL019345:51103-63368 17 (membrane-inserted)1.546096667 [Source:HGNC 1.2687 Symbol;Acc:HGNC:7163] ENSOCUG00000012312 CLEC4D C-type lectin8:33500036-33511624 domain family 4, member1.57747 D [Source:HGNC 1.294929Symbol;Acc:HGNC:14554] ENSOCUG00000017835 DNMT3B DNADraft (cytosine-5-)-methyltransferase4:6631097-66488821.644773333 3 beta [Source:HGNC 1.350323333 Symbol;Acc:HGNC:2979] ENSOCUG00000004484 GLRB glycine receptor,15:6787240-6908559 beta [Source:HGNC1.805873667 Symbol;Acc:HGNC:4329] 1.484493333 ENSOCUG00000026986 - Uncharacterized2:99179897-99184372 protein [Source:UniProtKB/TrEMBL;Acc:G1TPN5]1.318225 1.084754333 ENSOCUG00000006139 SEMA5B sema domain,14:96153283-96207393 seven thrombospondin1.86989 repeats (type 1 and 1.543071667 type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B [Source:HGNC Symbol;Acc:HGNC:10737] ENSOCUG00000014251 WDR31 WD repeat domain1:11368-33974 31 [Source:HGNC1.501403333 Symbol;Acc:HGNC:21421] 1.239486667 ENSOCUG00000006100 - Uncharacterized2:117959190-117972280 protein [Source:UniProtKB/TrEMBL;Acc:G1SQB6]1.753626667 1.449523 ENSOCUG00000017727 - UncharacterizedGL018705:5901595-5934446 protein [Source:UniProtKB/TrEMBL;Acc:G1TEA9]1.686663333 1.405536667 ENSOCUG00000003302 MAP6 microtubule-associated1:141093818-141162653 protein 1.9963166676 [Source:HGNC Symbol;Acc:HGNC:6868] 1.66467 ENSOCUG00000013508 IL17RB interleukin 179:20810587-20823902 receptor B [Source:HGNC1.380478333 Symbol;Acc:HGNC:18015] 1.154452333 ENSOCUG00000022568 - Uncharacterized4:37314596-37730050 protein [Source:UniProtKB/TrEMBL;Acc:G1TUM0]1.60144 1.340149333 ENSOCUG00000027783 - UncharacterizedGL019061:200375-201509 protein [Source:UniProtKB/TrEMBL;Acc:G1U0Y1]1.464323333 1.226852667 ENSOCUG00000007931 - GL018806:736872-7386211.97903 1.660356667 ENSOCUG00000000134 NTNG2 netrin G2 [Source:HGNCGL018764:893746-942350 Symbol;Acc:HGNC:14288]1.679126667 1.409230667 ENSOCUG00000017325 KCNAB3 potassium voltage-gated19:11157839-11351886 channel,1.221798333 shaker-related subfamily, 1.028991 beta member 3 [Source:HGNC Symbol;Acc:HGNC:6230] ENSOCUG00000007487 SLCO1C1 Uncharacterized8:18919288-18963202 protein [Source:UniProtKB/TrEMBL;Acc:G1ST61]1.499976667 1.264222 ENSOCUG00000025132 RPL23A Uncharacterized9:51698353-51698884 protein [Source:UniProtKB/TrEMBL;Acc:G1SE76]1.235870667 1.047354333 ENSOCUG00000012275 TEX9 testis expressed17:16094488-16213330 9 [Source:HGNC1.732163333 Symbol;Acc:HGNC:29585] 1.469910667 ENSOCUG00000014006 - UncharacterizedX:9773696-9798338 protein [Source:UniProtKB/TrEMBL;Acc:G1T6J2]1.195793333 1.016046 ENSOCUG00000000868 CCL20 chemokine (C-C7:169686708-169690295 motif) ligand 201.435256667 [Source:HGNC Symbol;Acc:HGNC:10619] 1.221311 ENSOCUG00000007439 NUDT15 nudix (nucleosideGL018705:1472465-1503846 diphosphate linked1.625606667 moiety X)-type motif 1.383326667 15 [Source:HGNC Symbol;Acc:HGNC:23063] ENSOCUG00000011291 - 20:21112453-211155121.456186667 1.23948 ENSOCUG00000025910 - 6:19259804-192606611.794286667 1.53164 ENSOCUG00000005262 ZMYND10 zinc finger, 9:17807466-17811591MYND-type containing1.751165 10 [Source:HGNC 1.494863333 Symbol;Acc:HGNC:19412] ENSOCUG00000004707 OLFM2 olfactomedinGL018833:338798-381943 2 [Source:HGNC 1.234873667Symbol;Acc:HGNC:17189] 1.057153333 ENSOCUG00000009890 DPY19L2 dpy-19-like 10:18826748-189223602 (C. elegans) [Source:HGNC1.927466667 Symbol;Acc:HGNC:19414] 1.65107 ENSOCUG00000015026 KIAA1614 KIAA1614 [Source:HGNCGL019023:4703-26314 Symbol;Acc:HGNC:29327]1.521773333 1.307423333 ENSOCUG00000017829 - UncharacterizedGL018828:155592-159413 protein [Source:UniProtKB/TrEMBL;Acc:G1TG65]1.373729667 1.180857333 ENSOCUG00000022745 - UncharacterizedGL018752:1383669-1411028 protein [Source:UniProtKB/TrEMBL;Acc:G1U2R5]1.983858667 1.706443333

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ENSOCUG00000004230 SLC9A7 solute carrierX:31726074-31894069 family 9, subfamily A 1.99612(NHE7, cation proton 1.717903333 antiporter 7), member 7 [Source:HGNC Symbol;Acc:HGNC:17123] ENSOCUG00000002281 CYP2U1 cytochrome 15:41584590-41605636P450, family 2, subfamily1.854056667 U, polypeptide 1.6031866671 [Source:HGNC Symbol;Acc:HGNC:20582] ENSOCUG00000013016 MAPK4 mitogen-activated9:91218873-91349856 protein kinase1.308778333 4 [Source:HGNC Symbol;Acc:HGNC:6878] 1.132165667 ENSOCUG00000023520 FLRT1 fibronectin leucineGL019379:9636-11646 rich transmembrane1.35175 protein 1 [Source:HGNC 1.170663333 Symbol;Acc:HGNC:3760] ENSOCUG00000017756 C3orf33 chromosome14:50029753-50049964 3 open reading frame1.433056667 33 [Source:HGNC 1.242256667Symbol;Acc:HGNC:26434] ENSOCUG00000023184 TAS1R1 taste receptor,13:143078112-143087432 type 1, member 1 [Source:HGNC1.3029 Symbol;Acc:HGNC:14448] 1.131121333 ENSOCUG00000011936 FHIT fragile histidine9:26530895-26825696 triad [Source:HGNC1.150207333 Symbol;Acc:HGNC:3701] 1.002367333 ENSOCUG00000000809 CDCA5 cell divisionGL018942:129121-138492 cycle associated 5 1.504005667[Source:HGNC Symbol;Acc:HGNC:14626] 1.311732 ENSOCUG00000027244 - UncharacterizedGL019453:52557-53765 protein [Source:UniProtKB/TrEMBL;Acc:G1TRU4]1.911203333 1.668396667 ENSOCUG00000029183 UBAP1L ubiquitin associated17:7199467-7210817 protein 1-like1.628716667 [Source:HGNC Symbol;Acc:HGNC:40028] 1.424226 ENSOCUG00000017930 SPIN4 spindlin family,X:41639816-41640563 member 4 [Source:HGNC1.55883 Symbol;Acc:HGNC:27040] 1.3677 ENSOCUG00000005611 ZNF691 zinc finger protein13:123894011-123895943 691 [Source:HGNC1.999816667 Symbol;Acc:HGNC:28028] 1.755826667 ENSOCUG00000029515 - Uncharacterized4:20067601-20284338 protein [Source:UniProtKB/TrEMBL;Acc:U3KP16]1.662343333 1.463217 ENSOCUG00000025363 - Uncharacterized18:4025889-4027416 protein [Source:UniProtKB/TrEMBL;Acc:G1TVI3]1.69325 1.494593333 ENSOCUG00000006484 KIF27 kinesin familyGL018728:933294-1023610 member 27 [Source:HGNC1.188729333 Symbol;Acc:HGNC:18632] 1.050405333 ENSOCUG00000001836 LPHN1 latrophilin 1GL019579:171-15297 [Source:HGNC Symbol;Acc:HGNC:20973]1.794343333 1.58619 ENSOCUG00000007068 CNBD2 cyclic nucleotide4:3867130-3919562 binding domain1.465923333 containing 2 [Source:HGNC 1.297916667 Symbol;Acc:HGNC:16145] ENSOCUG00000000877 C19orf59 mast cell-expressedGL018767:799370-802291 membrane 1.667343667protein 1 [Source:HGNC Symbol;Acc:HGNC:27291] 1.47878 ENSOCUG00000002733 CACNA1G calcium channel,19:37112579-37166280 voltage-dependent,1.803726667 T type, alpha 1G 1.602421333subunit [Source:HGNC Symbol;Acc:HGNC:1394] ENSOCUG00000000960 SDK2 sidekick cell19:56869392-57104403 adhesion molecule1.881143333 2 [Source:HGNC Symbol;Acc:HGNC:19308] 1.67468 ENSOCUG00000001727 SLC19A1 solute carrierGL019369:20-37567 family 19 (folate transporter),1.961293333 member 1 1.748496667[Source:HGNC Symbol;Acc:HGNC:10937] ENSOCUG00000012102 - 8:100934277-1012987341.591133333 1.420928667 ENSOCUG00000010629 - UncharacterizedDraftX:87968205-87969555 protein [Source:UniProtKB/TrEMBL;Acc:G1U6X6]1.698616667 1.526072667 ENSOCUG00000023729 S100Z S100 calciumGL018855:29653-31204 binding protein Z1.904956667 [Source:HGNC Symbol;Acc:HGNC:30367] 1.714157 ENSOCUG00000027203 AZGP1 alpha-2-glycoproteinGL018760:238892-246899 1, zinc-binding1.39052 [Source:HGNC Symbol;Acc:HGNC:910] 1.25373 ENSOCUG00000029203 ZFP37 ZFP37 zinc 1:341707-343258finger protein [Source:HGNC1.78479 Symbol;Acc:HGNC:12863] 1.610693333 ENSOCUG00000003061 SV2B synaptic vesicleGL018759:978053-1029659 glycoprotein 2B1.236621667 [Source:HGNC Symbol;Acc:HGNC:16874] 1.117786667 ENSOCUG00000006731 BDNF brain-derived1:166651994-166664193 neurotrophic factor [Source:HGNC1.80234 Symbol;Acc:HGNC:1033] 1.63072 ENSOCUG00000000777 - UncharacterizedAAGW02082281:5813-11802 protein [Source:UniProtKB/TrEMBL;Acc:G1SE17]1.777123333 1.611552 ENSOCUG00000015415 TDRP testis developmentGL018917:369758-374439 related protein1.539813333 [Source:HGNC Symbol;Acc:HGNC:26951] 1.396498 ENSOCUG00000026037 GNB1L guanine nucleotideGL018826:851604-883183 binding protein (G1.47546 protein), beta polypeptide 1.339703333 1-like [Source:HGNC Symbol;Acc:HGNC:4397] ENSOCUG00000015778 SLC25A47 solute carrierGL018904:87247-91813 family 25, member 47 1.88136[Source:HGNC Symbol;Acc:HGNC:20115] 1.709276667 ENSOCUG00000027589 U3 Small nucleolar19:29323714-29763354 RNA U3 [Source:RFAM;Acc:RF00012]1.43042 1.299626667 ENSOCUG00000027186 STYXL1 serine/threonine/tyrosine6:26863676-26893404 interacting-like1.88462 1 [Source:HGNC 1.714984333 Symbol;Acc:HGNC:18165] ENSOCUG00000029022 ZNF713 zinc finger proteinGL018788:940493-941246 713 [Source:HGNC1.707846667 Symbol;Acc:HGNC:22043] 1.556 ENSOCUG00000015001 CYB5R2 cytochrome 1:149213800-149223802b5 reductase 2 [Source:HGNC1.415656667 Symbol;Acc:HGNC:24376] 1.290476667 ENSOCUG00000004365 - UncharacterizedGL019105:153640-169785 protein [Source:UniProtKB/TrEMBL;Acc:G1SLN0]1.236762667 1.128261667 ENSOCUG00000029301 ZSCAN23 zinc finger and12:10502254-10511825 SCAN domain containing1.137278 23 [Source:HGNC 1.037674667 Symbol;Acc:HGNC:21193] ENSOCUG00000013621 GDF9 Oryctolagus3:15881595-15884110 cuniculus growth differentiation1.68613 factor 9 (GDF9), 1.539673333 mRNA. [Source:RefSeq mRNA;Acc:NM_001171350] ENSOCUG00000021310 - GL018717:3830280-38305861.164693 1.064857333 ENSOCUG00000021262 USP35 ubiquitin specific1:138527831-138561662 peptidase 35 [Source:HGNC1.359813333 Symbol;Acc:HGNC:20061] 1.24489 ENSOCUG00000008401 SCNN1B amiloride-sensitive6:14107571-14167778 sodium channel1.522211667 subunit beta [Source:RefSeq 1.393873667 peptide;Acc:NP_001076244] ENSOCUG00000017764 FIGF c-fos inducedX:1211430-1243195 growth factor (vascular1.893863333 endothelial growth 1.736473333 factor D) [Source:HGNC Symbol;Acc:HGNC:3708] ENSOCUG00000016105 COLQ collagen-like14:1532425-1596609 tail subunit (single1.337779667 strand of homotrimer) 1.226673333 of asymmetric acetylcholinesterase [Source:HGNC Symbol;Acc:HGNC:2226] ENSOCUG00000002189 KCNIP4 Kv channel 2:11313618-11493120interacting protein 4 [Source:HGNC1.19756 Symbol;Acc:HGNC:30083] 1.099689333 ENSOCUG00000010871 DNALI1 dynein, axonemal,GL018704:908982-915505 light intermediate1.417895667 chain 1 [Source:HGNC 1.302408333 Symbol;Acc:HGNC:14353] ENSOCUG00000017400 POP1 processing of3:113900041-113932752 precursor 1, ribonuclease1.29799 P/MRP subunit (S. 1.192417 cerevisiae) [Source:HGNC Symbol;Acc:HGNC:30129] ENSOCUG00000017204 DAB1 Dab, reelin signal13:109553760-109873740 transducer, homolog1.578136667 1 (Drosophila) 1.459276667[Source:HGNC Symbol;Acc:HGNC:2661] ENSOCUG00000005892 ARHGAP33 Rho GTPaseGL018786:600116-609862 activating protein 1.16113666733 [Source:HGNC Symbol;Acc:HGNC:23085] 1.076672667 ENSOCUG00000024545 PASK PAS domainGL018993:45-29598 containing serine/threonine1.92608 kinase [Source:HGNC 1.786593333 Symbol;Acc:HGNC:17270]

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ENSOCUG00000000066 USP27X ubiquitin specificX:34098748-34100638 peptidase 27, 1.909876667X-linked [Source:HGNC Symbol;Acc:HGNC:13486] 1.77364 ENSOCUG00000012794 SFR1 SWI5-dependent18:52049937-52054455 recombination repair1.94476 1 [Source:HGNC 1.806816667 Symbol;Acc:HGNC:29574] ENSOCUG00000010352 - 16:67460741-674628751.524442667 1.424082667 ENSOCUG00000023744 CDKL1 cyclin-dependent17:69392401-69461824 kinase-like 1 (CDC2-related1.639046667 kinase) 1.532432667[Source:HGNC Symbol;Acc:HGNC:1781] ENSOCUG00000012203 SGSM1 small G proteinGL018766:332274-398111 signaling modulator 1.321391 [Source:HGNC Symbol;Acc:HGNC:29410] 1.23569 ENSOCUG00000011606 SLC35E4 solute carrier21:3193801-3205732 family 35, member1.827293333 E4 [Source:HGNC Symbol;Acc:HGNC:17058] 1.709506667 ENSOCUG00000015833 SAMSN1 SAM domain,14:142370847-142535048 SH3 domain and1.186953333 nuclear localization signals 1.112869 1 [Source:HGNC Symbol;Acc:HGNC:10528] ENSOCUG00000006044 PPIL6 peptidylprolyl12:97353724-97392637 isomerase (cyclophilin)-like1.35354 6 [Source:HGNC 1.269669667 Symbol;Acc:HGNC:21557] ENSOCUG00000007434 PGLYRP1 peptidoglycanAAGW02083348:224-4334 recognition protein1.829993333 1 [Source:HGNC Symbol;Acc:HGNC:8904] 1.718673333 ENSOCUG00000027001 SAC3D1 SAC3 domainGL018942:109651-110684 containing 1 [Source:HGNC1.079033333 Symbol;Acc:HGNC:30179] 1.013996667 ENSOCUG00000005671 - solute carrier15:46632430-46709870 family 9, subfamily B1.177475 (NHA1, cation proton 1.107479333 antiporter 1), member 1 [Source:HGNC Symbol;Acc:HGNC:24244] ENSOCUG00000002706 MYCBPAP MYCBP associated19:37197030-37218898 protein [Source:HGNC1.841813333 Symbol;Acc:HGNC:19677] 1.734996667 ENSOCUG00000006012 - Uncharacterized20:31421765-31433188 protein [Source:UniProtKB/TrEMBL;Acc:G1SQ49]1.754306667 1.652633333 ENSOCUG00000025440 - UncharacterizedGL018752:263670-265128 protein [Source:UniProtKB/TrEMBL;Acc:G1U6I8]1.885076667 1.776366667 ENSOCUG00000016140 TBXAS1 thromboxaneGL018774:255384-495477 A synthase 1 (platelet)1.213963667 [Source:HGNC Symbol;Acc:HGNC:11609] 1.145967667 ENSOCUG00000027804 SOBP sine oculis binding12:95579419-95725306 protein homolog1.134944667 (Drosophila) [Source:HGNC 1.072644333 Symbol;Acc:HGNC:29256] ENSOCUG00000004897 FLT3 fms-related GL018735:1068364-1133192tyrosine kinase 3 [Source:HGNC1.911733333 Symbol;Acc:HGNC:3765] 1.80688 ENSOCUG00000005972 HESX1 HESX homeobox9:24073511-24075638 1 [Source:HGNC1.458578 Symbol;Acc:HGNC:4877] 1.37974 ENSOCUG00000002264 SAC adenylate cyclase13:25092814-25207278 type 10 [Source:RefSeq1.450513 peptide;Acc:NP_001075622] 1.372502667 ENSOCUG00000013076 APOBR apolipoprotein6:18601895-18609424 B receptor [Source:HGNC1.221762 Symbol;Acc:HGNC:24087] 1.158266333 ENSOCUG00000028039 CHGB chromogranin4:12352370-12366948 B (secretogranin 1.7245833331) [Source:HGNC Symbol;Acc:HGNC:1930] 1.635163333 ENSOCUG00000006769 BTNL2 butyrophilin-like12:23019701-23048054 2 (MHC class II associated)1.88719 [Source:HGNC 1.789401333 Symbol;Acc:HGNC:1142] ENSOCUG00000012065 PTPRR proteinDraft tyrosine4:49652484-49939796 phosphatase, receptor1.12297 type, R [Source:HGNC 1.065053333 Symbol;Acc:HGNC:9680] ENSOCUG00000003737 ACRBP acrosin binding8:32673742-32684515 protein [Source:HGNC1.208349 Symbol;Acc:HGNC:17195] 1.14621 ENSOCUG00000026633 ZNF597 zinc finger proteinGL018828:655502-659535 597 [Source:HGNC1.101384 Symbol;Acc:HGNC:26573] 1.045708667 ENSOCUG00000025890 - UncharacterizedGL019309:57908-63003 protein [Source:UniProtKB/TrEMBL;Acc:G1U159]1.724933333 1.645088667 ENSOCUG00000012282 MNS1 meiosis-specific17:16094488-16213330 nuclear structural 11.291255 [Source:HGNC Symbol;Acc:HGNC:29636] 1.23451 ENSOCUG00000011100 RANBP17 RAN binding3:52186052-52553232 protein 17 [Source:HGNC1.086969 Symbol;Acc:HGNC:14428] 1.040466333 ENSOCUG00000001898 GLP1R glucagon-like12:28880844-28918067 peptide 1 receptor [Source:HGNC1.054539 Symbol;Acc:HGNC:4324] 1.011141 ENSOCUG00000027991 SAPCD1 suppressor APC12:20580886-20582291 domain containing1.975903667 1 [Source:HGNC Symbol;Acc:HGNC:13938] 1.89674 ENSOCUG00000010889 RFESD Rieske (Fe-S)11:15305619-15347150 domain containing [Source:HGNC1.3237 Symbol;Acc:HGNC:29587] 1.271944333 ENSOCUG00000003485 C11orf80 chromosome1:194400514-194438187 11 open reading frame1.122772333 80 [Source:HGNC Symbol;Acc:HGNC:26197] 1.080827 ENSOCUG00000010080 LRRC36 leucine rich 5:22920427-22980125repeat containing 361.242686667 [Source:HGNC Symbol;Acc:HGNC:25615] 1.196430667 ENSOCUG00000008358 CABP1 calcium binding21:11932155-11947835 protein 1 [Source:HGNC1.410323333 Symbol;Acc:HGNC:1384] 1.359102333 ENSOCUG00000005493 DFNB59 deafness, autosomal7:118109780-118136231 recessive 591.449143333 [Source:HGNC Symbol;Acc:HGNC:29502] 1.398960667 ENSOCUG00000002551 CNTLN centlein, centrosomal1:36539441-36916529 protein [Source:HGNC1.465276667 Symbol;Acc:HGNC:23432] 1.415784 ENSOCUG00000013559 SLAMF7 SLAM family13:32319848-32338970 member 7 [Source:HGNC1.196838 Symbol;Acc:HGNC:21394] 1.156757 ENSOCUG00000002655 HEPACAM hepatic and 1:92321747-92334381glial cell adhesion molecule1.42166 [Source:HGNC Symbol;Acc:HGNC:26361] 1.37428 ENSOCUG00000017191 ART4 Uncharacterized8:24750077-24763982 protein [Source:UniProtKB/TrEMBL;Acc:G1TD66]1.317910667 1.274003667 ENSOCUG00000006973 EMR2 egf-like moduleGL018901:416024-448569 containing, mucin-like,1.210092667 hormone receptor-like 1.170738667 2 [Source:HGNC Symbol;Acc:HGNC:3337] ENSOCUG00000005398 CCNE2 Uncharacterized3:110486502-110500646 protein [Source:UniProtKB/TrEMBL;Acc:G1SNU7]1.97825 1.914523333 ENSOCUG00000026315 - UncharacterizedGL018829:165180-167536 protein [Source:UniProtKB/TrEMBL;Acc:G1U5F8]1.556800667 1.509476667 ENSOCUG00000022810 USP51 ubiquitin specificX:36769604-36771725 peptidase 51 [Source:HGNC1.151671 Symbol;Acc:HGNC:23086] 1.116908333 ENSOCUG00000016517 EEFSEC eukaryotic elongation9:7127235-7501512 factor, selenocysteine-tRNA-specific1.985196667 1.925896667 [Source:HGNC Symbol;Acc:HGNC:24614] ENSOCUG00000004892 RNF2 ring finger proteinGL018801:661700-673463 2 [Source:HGNC1.531377 Symbol;Acc:HGNC:10061] 1.488913333 ENSOCUG00000027319 DNAH10 dynein, axonemal,GL019178:92891-122045 heavy chain 10 [Source:HGNC1.060366 Symbol;Acc:HGNC:2941] 1.031793333 ENSOCUG00000006248 - UncharacterizedGL018910:270415-316649 protein [Source:UniProtKB/TrEMBL;Acc:G1SQM0]1.707079333 1.661428667 ENSOCUG00000022122 ZNF467 zinc finger proteinGL018806:859908-866585 467 [Source:HGNC1.630996667 Symbol;Acc:HGNC:23154] 1.590001 ENSOCUG00000016195 MTBP MDM2 binding3:136273884-136364423 protein [Source:HGNC1.192419 Symbol;Acc:HGNC:7417] 1.162776 ENSOCUG00000024024 - UncharacterizedGL018776:552887-556202 protein [Source:UniProtKB/TrEMBL;Acc:G1TLQ9]1.515963333 1.479948667

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ENSOCUG00000022761 IL3RA interleukin 32:34310585-34319499 receptor, alpha (low1.883086667 affinity) [Source:HGNC 1.843276667 Symbol;Acc:HGNC:6012] ENSOCUG00000002630 HAPLN1 hyaluronan and11:3877961-3959574 proteoglycan link1.403066667 protein 1 [Source:HGNC 1.374030333 Symbol;Acc:HGNC:2380] ENSOCUG00000027187 PRG4 proteoglycan16:84071665-84087469 4 [Source:HGNC Symbol;Acc:HGNC:9364]1.68551 1.651061667 ENSOCUG00000025281 - GL018702:7279895-72877901.503227667 1.472776667 ENSOCUG00000003303 CD83 CD83 molecule12:7795779-7822303 [Source:HGNC Symbol;Acc:HGNC:1703]1.435837 1.408394 ENSOCUG00000015372 DQX1 DEAQ box 2:112015740-112023178RNA-dependent ATPase1.813553333 1 [Source:HGNC 1.780356667 Symbol;Acc:HGNC:20410] ENSOCUG00000004447 ALPL alkaline phosphatase,13:131691933-131705875 liver/bone/kidney1.118957 [Source:HGNC Symbol;Acc:HGNC:438] 1.098953 ENSOCUG00000025911 PTGES3 Uncharacterized16:26236690-26237173 protein [Source:UniProtKB/TrEMBL;Acc:G1U859]1.667746667 1.639324 ENSOCUG00000011985 CACNA1A calcium channel,GL018984:140567-258661 voltage-dependent,1.466119667 P/Q type, alpha 1A 1.443306667 subunit [Source:HGNC Symbol;Acc:HGNC:1388] ENSOCUG00000025760 MEIS3 Meis homeoboxGL018835:639112-645010 3 [Source:HGNC Symbol;Acc:HGNC:29537]1.58126 1.557396 ENSOCUG00000025279 C9orf152 chromosome1:2982146-2987010 9 open reading frame1.638293333 152 [Source:HGNC 1.614986667 Symbol;Acc:HGNC:31455] ENSOCUG00000017402 ARSG arylsulfatase19:52250501-52370846 G [Source:HGNC 1.805766667Symbol;Acc:HGNC:24102] 1.78282 ENSOCUG00000010206 DEFB125 defensin, beta4:7866260-7866572 125 [Source:HGNC Symbol;Acc:HGNC:18105]1.55775 1.538913333 ENSOCUG00000023151 SLAMF1 signaling lymphocytic13:32433476-32472146 activation1.358307333 molecule family member 1.345446333 1 [Source:HGNC Symbol;Acc:HGNC:10903] ENSOCUG00000010048 AFMID arylformamidaseGL019309:12082-32279 [Source:HGNC Symbol;Acc:HGNC:20910]1.37231 1.361414333 ENSOCUG00000003943 CLCF1 cardiotrophin-like1:194811737-194819288 cytokine factor1.303280333 1 [Source:HGNC Symbol;Acc:HGNC:17412] 1.294182667 ENSOCUG00000025677 CCR3 chemokine (C-C9:14490512-14492301 motif) receptor1.754981333 3 [Source:HGNC Symbol;Acc:HGNC:1604] 1.74283 ENSOCUG00000002466 STAT4 signal transducer7:131466898-131585472 and activator of1.992986667 transcription 4 [Source:HGNC 1.97946 Symbol;Acc:HGNC:11365] ENSOCUG00000025236 - Oryctolagus9:15250356-15366609 cuniculus leukocyte protein1.655698 (LOC100009166), 1.64483mRNA. [Source:RefSeq mRNA;Acc:NM_001082325] ENSOCUG00000024068 OR52W1 olfactory receptor,1:147208893-147256823 family 52, subfamily1.021841333 W, member 1 1.016842333[Source:HGNC Symbol;Acc:HGNC:15239] ENSOCUG00000011488 FANCI Fanconi anemia,GL018738:2190505-2294419 complementation1.718433333 group I [Source:HGNC 1.712313333 Symbol;Acc:HGNC:25568] ENSOCUG00000005995 DNM3 dynamin 3 [Source:HGNC13:20361286-20962076 Symbol;Acc:HGNC:29125]1.194913333 1.190725667 ENSOCUG00000025176 - Draft15:14712280-15173547 1.19739 1.193714667 ENSOCUG00000022096 - Uncharacterized16:33982154-33983451 protein [Source:UniProtKB/TrEMBL;Acc:G1TY80]1.246953333 1.243408 ENSOCUG00000011789 ARMC2 armadillo repeat12:96801227-96930763 containing 2 [Source:HGNC1.103583333 Symbol;Acc:HGNC:23045] 1.102126667 ENSOCUG00000013288 MTTP microsomal 15:50209381-50272383triglyceride transfer1.337237333 protein [Source:HGNC 1.335557333 Symbol;Acc:HGNC:7467] ENSOCUG00000006031 TLR6 toll-like receptor2:28246015-28248436 6 [Source:HGNC1.360363333 Symbol;Acc:HGNC:16711] 1.35931 ENSOCUG00000014019 SPIRE2 spire-type actinGL018965:95344-118788 nucleation factor1.771213333 2 [Source:HGNC Symbol;Acc:HGNC:30623] 1.772346667 ENSOCUG00000010372 - Uncharacterized16:34638353-34715576 protein [Source:UniProtKB/TrEMBL;Acc:G1SZ61]1.73125 1.735526667 ENSOCUG00000009066 SAMD12 sterile alpha3:134047652-134535910 motif domain containing1.849783333 12 [Source:HGNC 1.854546667 Symbol;Acc:HGNC:31750] ENSOCUG00000017825 METTL25 methyltransferase4:61629399-61742090 like 25 [Source:HGNC1.9287 Symbol;Acc:HGNC:26228] 1.93664 ENSOCUG00000017565 - kielin/chordin-like7:15674383-15696613 protein [Source:HGNC1.118078333 Symbol;Acc:HGNC:17585] 1.122972333 ENSOCUG00000025186 - Uncharacterized4:83004479-83080635 protein [Source:UniProtKB/TrEMBL;Acc:G1TZH2]1.40187 1.40951 ENSOCUG00000013310 AMT aminomethyltransferase9:16892373-16958642 [Source:HGNC1.30985 Symbol;Acc:HGNC:473] 1.317058667 ENSOCUG00000023803 CENPL centromere protein13:1158969-1169846 L [Source:HGNC1.304656667 Symbol;Acc:HGNC:17879] 1.314386 ENSOCUG00000023096 HPX Oryctolagus1:147446112-147454581 cuniculus hemopexin (HPX),1.87397 mRNA. [Source:RefSeq 1.888736667 mRNA;Acc:NM_001082760] ENSOCUG00000017309 HTR4 5-hydroxytryptamine3:30426021-30570451 (serotonin) receptor1.78884 4, G protein-coupled 1.804326667 [Source:HGNC Symbol;Acc:HGNC:5299] ENSOCUG00000029071 ZNF81 zinc finger proteinX:32954540-32971235 81 [Source:HGNC1.400920667 Symbol;Acc:HGNC:13156] 1.413683333 ENSOCUG00000026770 - 1:174934219-1749355361.237611333 1.251580333 ENSOCUG00000015932 - synapsin II [Source:HGNC9:11735390-11932910 Symbol;Acc:HGNC:11495]1.499856667 1.51696 ENSOCUG00000009356 PKDREJ UncharacterizedGL018928:266770-273248 protein [Source:UniProtKB/TrEMBL;Acc:G1SX22]1.903486667 1.927713333 ENSOCUG00000012469 TCTEX1D4 Tctex1 domain13:121822598-121823258 containing 4 [Source:HGNC1.469928333 Symbol;Acc:HGNC:32315] 1.489259 ENSOCUG00000008845 ZNF583 zinc finger proteinGL018811:114499-130591 583 [Source:HGNC1.66146 Symbol;Acc:HGNC:26427] 1.68587 ENSOCUG00000008581 CDYL2 chromodomain5:35045034-35294457 protein, Y-like 2 [Source:HGNC1.226148 Symbol;Acc:HGNC:23030] 1.244669 ENSOCUG00000004525 NDUFAF2 NADH dehydrogenase11:76998436-77189606 (ubiquinone)1.636916667 complex I, assembly 1.662063667 factor 2 [Source:HGNC Symbol;Acc:HGNC:28086] ENSOCUG00000016881 RHEBL1 Ras homolog4:33360199-33362993 enriched in brain like 11.83851 [Source:HGNC Symbol;Acc:HGNC:21166] 1.867196667 ENSOCUG00000000515 LGALS4 lectin, galactoside-binding,5:949252-956946 soluble,1.171245 4 [Source:HGNC Symbol;Acc:HGNC:6565] 1.193450333 ENSOCUG00000028133 SHROOM1 shroom family3:15854493-15858877 member 1 [Source:HGNC1.458600667 Symbol;Acc:HGNC:24084] 1.490503333 ENSOCUG00000004332 MYRIP myosin VIIA9:3603739-3925918 and Rab interacting1.483453333 protein [Source:HGNC Symbol;Acc:HGNC:19156] 1.516401 ENSOCUG00000021288 - Uncharacterized5:1262241-1266547 protein [Source:UniProtKB/TrEMBL;Acc:G1TUH1]1.423013333 1.454956667

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ENSOCUG00000009582 CLEC5A C-type lectinGL018758:681291-692294 domain family 5, 1.164077333member A [Source:HGNC 1.190662667 Symbol;Acc:HGNC:2054] ENSOCUG00000014250 TRDC T cell receptor17:42732499-42743319 delta constant [Source:HGNC1.244684 Symbol;Acc:HGNC:12253] 1.274379 ENSOCUG00000012987 - Uncharacterized17:20642961-20685200 protein [Source:UniProtKB/TrEMBL;Acc:G1T4H0]1.117648 1.146482 ENSOCUG00000026025 CCDC65 coiled-coil domain4:33208160-33238380 containing 65 [Source:HGNC1.073935 Symbol;Acc:HGNC:29937] 1.101930333 ENSOCUG00000026462 LUZP2 leucine zipper1:163681971-164228470 protein 2 [Source:HGNC1.796973333 Symbol;Acc:HGNC:23206] 1.845726667 ENSOCUG00000003491 CCDC85A coiled-coil domain2:129656417-129881667 containing 85A1.709203333 [Source:HGNC Symbol;Acc:HGNC:29400] 1.756916667 ENSOCUG00000002418 SAAL1 serum amyloidGL018733:2091725-2126454 A-like 1 [Source:HGNC1.923153333 Symbol;Acc:HGNC:25158] 1.978033333 ENSOCUG00000008721 HLA-DPB1 major histocompatibility12:23554065-23562038 complex, class1.73073 II, DP beta 1 [Source:HGNC 1.780152333 Symbol;Acc:HGNC:4940] ENSOCUG00000001918 MORN3 MORN repeat21:5990745-6004820 containing 3 [Source:HGNC1.189362 Symbol;Acc:HGNC:29807] 1.223383333 ENSOCUG00000002656 TRAPPC3L trafficking protein12:104750735-104836786 particle complex1.278759667 3-like [Source:HGNC 1.316126Symbol;Acc:HGNC:21090] ENSOCUG00000000554 NME6 NME/NM239:16038670-16047007 nucleoside diphosphate1.658806667 kinase 6 [Source:HGNC 1.708173333 Symbol;Acc:HGNC:20567] ENSOCUG00000027980 RPL23A Uncharacterized4:53194044-53194515 protein [Source:UniProtKB/TrEMBL;Acc:G1SE76]1.084247 1.116549 ENSOCUG00000003040 ADAMTS3 ADAM metallopeptidase15:77518040-77836614 with thrombospondin1.835273333 type 1 motif, 1.89305 3 [Source:HGNC Symbol;Acc:HGNC:219] ENSOCUG00000023195 - UncharacterizedGL019183:330-32495 protein [Source:UniProtKB/TrEMBL;Acc:G1TZH8]1.533921 1.583506667 ENSOCUG00000009115 - Uncharacterized21:6474248-6537283 protein [Source:UniProtKB/TrEMBL;Acc:G1SUV5]1.301520333 1.343858333 ENSOCUG00000014499 CLSTN3 calsyntenin 8:33100542-331386573 [Source:HGNC Symbol;Acc:HGNC:18371]1.179313333 1.21786 ENSOCUG00000009489 - Rho GTPase17:37760082-37856624 activating protein 1.50001333311A [Source:HGNC Symbol;Acc:HGNC:15783] 1.552606667 ENSOCUG00000009809 SP110 SP110 nuclear7:172093072-172131575 body protein [Source:HGNC1.290371 Symbol;Acc:HGNC:5401] 1.335873333 ENSOCUG00000011158 FAM131B family with 7:8747339-8788889sequence similarity1.401142333 131, member B [Source:HGNC 1.451116667 Symbol;Acc:HGNC:22202] ENSOCUG00000006292 TFEC transcription7:29221335-29365932 factor EC [Source:HGNC1.380121 Symbol;Acc:HGNC:11754] 1.429424333 ENSOCUG00000022962 - GL018805:796323-7972821.408136667 1.45877 ENSOCUG00000026975 TSSK6 testis-specificGL019137:142349-143168 serine kinase 6 [Source:HGNC1.329777333 Symbol;Acc:HGNC:30410] 1.379497 ENSOCUG00000029728 - Draft16:67011510-670478521.727876667 1.79688 ENSOCUG00000012201 PPAT phosphoribosyl15:92442278-92503582 pyrophosphate 1.879476667amidotransferase [Source:HGNC 1.956286667 Symbol;Acc:HGNC:9238] ENSOCUG00000027280 - UncharacterizedAAGW02082002:3255-3856 protein [Source:UniProtKB/TrEMBL;Acc:G1TZS6]1.34147 1.396446667 ENSOCUG00000012963 SCAI suppressor ofGL018699:2220300-2378637 cancer cell invasion [Source:HGNC1.869085 Symbol;Acc:HGNC:26709] 1.947263333 ENSOCUG00000011952 - Glutathione 12:42452895-42469789S-transferase [Source:UniProtKB/TrEMBL;Acc:G1T2B1]1.011156667 1.054546667 ENSOCUG00000015149 TSPEAR thrombospondin-typeGL019021:209774-231347 laminin G domain1.105144 and EAR repeats 1.154271667 [Source:HGNC Symbol;Acc:HGNC:1268] ENSOCUG00000001255 REM2 RAS (RAD 17:43115446-43118974and GEM)-like GTP1.445953333 binding 2 [Source:HGNC 1.511237 Symbol;Acc:HGNC:20248] ENSOCUG00000008307 - Uncharacterized13:34980686-34984301 protein [Source:UniProtKB/TrEMBL;Acc:G1SUW8]1.236194667 1.293715 ENSOCUG00000022748 STX11 syntaxin 11 12:134906248-134907106[Source:HGNC Symbol;Acc:HGNC:11429]1.167753 1.222766667 ENSOCUG00000028144 PIH1D2 PIH1 domain1:104308327-104313061 containing 2 [Source:HGNC1.20492 Symbol;Acc:HGNC:25210] 1.262073333 ENSOCUG00000013017 ELOVL2 ELOVL fatty12:4729514-4788523 acid elongase 2 [Source:HGNC1.025432333 Symbol;Acc:HGNC:14416] 1.074369 ENSOCUG00000000674 KCNA5 Oryctolagus8:31128085-31129953 cuniculus potassium1.509963333 voltage-gated channel, 1.582531667 shaker-related subfamily, member 5 (KCNA5), mRNA. [Source:RefSeq mRNA;Acc:NM_001082036] ENSOCUG00000021600 - PDZ domain1:134727885-134729038 containing 1 [Source:HGNC1.125984 Symbol;Acc:HGNC:8821] 1.180531667 ENSOCUG00000015702 EPOR erythropoietinGL019404:30-6532 receptor [Source:HGNC1.22221 Symbol;Acc:HGNC:3416] 1.283056667 ENSOCUG00000008587 TNFSF4 Tumor necrosis13:699462-888465 factor ligand superfamily1.53803 member 4 [Source:UniProtKB/Swiss-Prot;Acc:O02765] 1.615026667 ENSOCUG00000002952 - Uncharacterized8:28312993-28314382 protein [Source:UniProtKB/TrEMBL;Acc:G1SIQ0]1.145066667 1.203105667 ENSOCUG00000023590 SOWAHB sosondowah15:73520193-73520676 ankyrin repeat domain1.822706667 family member B [Source:HGNC 1.915111667 Symbol;Acc:HGNC:32958] ENSOCUG00000022539 - UncharacterizedGL018910:18719-32041 protein [Source:UniProtKB/TrEMBL;Acc:G1SPA3]1.009602667 1.061352 ENSOCUG00000005035 MAP3K13 mitogen-activated14:80101264-80268225 protein kinase1.771436667 kinase kinase 13 [Source:HGNC 1.862556667 Symbol;Acc:HGNC:6852] ENSOCUG00000010678 - 19:31415242-314159411.011299333 1.063881667 ENSOCUG00000011399 TTLL5 tubulin tyrosine20:29183847-29487951 ligase-like family,1.723756667 member 5 [Source:HGNC 1.814326667 Symbol;Acc:HGNC:19963] ENSOCUG00000009012 FCRL5 Fc receptor-like13:35617494-35669870 5 [Source:HGNC Symbol;Acc:HGNC:18508]1.050573 1.105783333 ENSOCUG00000013648 SLC16A9 solute carrier18:26445928-26515978 family 16, member1.113186667 9 [Source:HGNC Symbol;Acc:HGNC:23520] 1.171856667 ENSOCUG00000021351 GAPT GRB2-binding11:74425244-74425718 adaptor protein, 1.225408667transmembrane [Source:HGNC 1.291443333 Symbol;Acc:HGNC:26588] ENSOCUG00000029691 - UncharacterizedGL018889:384063-472883 protein [Source:UniProtKB/TrEMBL;Acc:U3KP18]1.292450667 1.363285 ENSOCUG00000011196 LAG3 lymphocyte-activation8:32792469-32799679 gene 3 [Source:HGNC1.82373 Symbol;Acc:HGNC:6476] 1.927394667 ENSOCUG00000001548 RASEF RAS and EF-hand1:69537918-69647427 domain containing1.232279 [Source:HGNC Symbol;Acc:HGNC:26464] 1.30314 ENSOCUG00000005239 SNX20 sorting nexinGL018732:160282-171151 20 [Source:HGNC Symbol;Acc:HGNC:30390]1.49352 1.579475667

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ENSOCUG00000002376 HAUS7 HAUS augmin-likeGL018816:900474-923179 complex, subunit1.65215 7 [Source:HGNC 1.747303333 Symbol;Acc:HGNC:32979] ENSOCUG00000021929 CCRL2 chemokine (C-C9:14578329-14579394 motif) receptor-like1.180958667 2 [Source:HGNC Symbol;Acc:HGNC:1612] 1.24955 ENSOCUG00000028058 CHAC2 ChaC, cation2:132460875-132471031 transport regulator homolog1.37701 2 (E. coli) [Source:HGNC 1.457126667 Symbol;Acc:HGNC:32363] ENSOCUG00000013170 1-Mar mitochondrial16:52275709-52301970 amidoxime reducing1.708246667 component 1 [Source:HGNC 1.810126667 Symbol;Acc:HGNC:26189] ENSOCUG00000002945 MEOX1 mesenchyme19:44102237-44118149 homeobox 1 [Source:HGNC1.65088 Symbol;Acc:HGNC:7013] 1.751733333 ENSOCUG00000003533 RASGRF2 Ras protein-specific11:1452934-1638962 guanine nucleotide-releasing1.069708 factor 2 1.135145[Source:HGNC Symbol;Acc:HGNC:9876] ENSOCUG00000011402 IL7R interleukin 711:57148914-57177886 receptor [Source:HGNC1.519966667 Symbol;Acc:HGNC:6024] 1.616303333 ENSOCUG00000004575 SLA2 Src-like-adaptor4:3370121-3396223 2 [Source:HGNC Symbol;Acc:HGNC:17329]1.163584 1.239255 ENSOCUG00000004026 CEP128 centrosomal20:24364963-24858408 protein 128kDa [Source:HGNC1.182054667 Symbol;Acc:HGNC:20359] 1.25918 ENSOCUG00000001536 ST1A8 Oryctolagus6:18528008-18531182 cuniculus arylsulfotransferase1.871541 ST1A8 (ST1A8), 1.994348 mRNA. [Source:RefSeq mRNA;Acc:NM_001160287] ENSOCUG00000024161 KCNJ15 potassium inwardly-rectifyingGL018727:2322687-2323815 channel,1.169504333 subfamily J, member 1.248829667 15 [Source:HGNC Symbol;Acc:HGNC:6261] ENSOCUG00000021369 SWSAP1 SWIM-typeGL019404:30-6532 zinc finger 7 associated1.849803333 protein 1 [Source:HGNC 1.97689 Symbol;Acc:HGNC:26638] ENSOCUG00000029709 - Uncharacterized13:133602393-133605961 protein [Source:UniProtKB/TrEMBL;Acc:U3KMZ9]1.56074 1.668853333 ENSOCUG00000007702 TBC1D10C TBC1 domain1:194839407-194845681 family, member 1.50977333310C [Source:HGNC Symbol;Acc:HGNC:24702] 1.620896667 ENSOCUG00000003274 OIP5 Opa interacting17:30737648-30791085 protein 5 [Source:HGNC1.022859667 Symbol;Acc:HGNC:20300] 1.0986 ENSOCUG00000021002 LCN2 lipocalin 2 [Source:HGNCGL018847:453614-456754 Symbol;Acc:HGNC:6526]1.63993 1.761589667 ENSOCUG00000013003 SCN3A sodium channel,7:104492489-104606995 voltage-gated, 1.135991333type III, alpha subunit 1.221758333[Source:HGNC Symbol;Acc:HGNC:10590] ENSOCUG00000003095 KIAA1524 KIAA1524 [Source:HGNC14:110813894-110944848 Symbol;Acc:HGNC:29302]1.465416667 1.576193333 ENSOCUG00000009071 KIF24 kinesin family1:19527230-19586628 member 24 [Source:HGNC1.070306 Symbol;Acc:HGNC:19916] 1.152717667 ENSOCUG00000025002 - 40S ribosomal13:50194935-50195316 protein S27 [Source:UniProtKB/TrEMBL;Acc:G1TZ76]1.432357333 1.546974 ENSOCUG00000022672 AMIGO3 adhesion molecule9:17207706-17243027 with Ig-like 1.701306667domain 3 [Source:HGNC Symbol;Acc:HGNC:24075] 1.84094 ENSOCUG00000029125 - Uncharacterized11:23777717-23778960 protein [Source:UniProtKB/TrEMBL;Acc:U3KNR0]1.568456667 1.69765 ENSOCUG00000010196 REEP1 receptorDraft accessory2:100020319-100143871 protein 1 [Source:HGNC1.691830333 Symbol;Acc:HGNC:25786] 1.83199 ENSOCUG00000022112 - Uncharacterized16:68897949-68909008 protein [Source:UniProtKB/TrEMBL;Acc:G1U7V8]1.126904 1.221377667 ENSOCUG00000024529 - Uncharacterized3:100731252-100746620 protein [Source:UniProtKB/TrEMBL;Acc:G1U2W1]1.185739667 1.287926667 ENSOCUG00000029050 - zinc finger protein5:1376768-1400036 527 [Source:HGNC1.125923333 Symbol;Acc:HGNC:29385] 1.223213333 ENSOCUG00000006897 TTC16 tetratricopeptideGL018699:285-19364 repeat domain 1.78383666716 [Source:HGNC Symbol;Acc:HGNC:26536] 1.94034 ENSOCUG00000029457 - UncharacterizedGL019214:94208-107219 protein [Source:UniProtKB/TrEMBL;Acc:U3KP67]1.744396667 1.897503333 ENSOCUG00000016180 F2 coagulation 1:186084681-186102084factor II (thrombin)1.454746667 [Source:HGNC Symbol;Acc:HGNC:3535] 1.585413333 ENSOCUG00000015475 USP43 ubiquitin specific19:9724793-9792615 peptidase 43 [Source:HGNC1.801453333 Symbol;Acc:HGNC:20072] 1.963876667 ENSOCUG00000022079 - Uncharacterized11:72057587-72083072 protein [Source:UniProtKB/TrEMBL;Acc:G1TNJ4]1.35876 1.48306 ENSOCUG00000017170 - SLIT-ROBOGL018802:957259-1000485 Rho GTPase activating1.414084333 protein 3 [Source:HGNC 1.544796667 Symbol;Acc:HGNC:19744] ENSOCUG00000006103 - Uncharacterized12:38737938-38750810 protein [Source:UniProtKB/TrEMBL;Acc:G1SQB8]1.154670333 1.26271 ENSOCUG00000022143 - Uncharacterized3:33240087-33254598 protein [Source:UniProtKB/TrEMBL;Acc:G1U118]1.576203333 1.72415 ENSOCUG00000016496 MLPH UncharacterizedGL018840:531574-568072 protein [Source:UniProtKB/TrEMBL;Acc:G1TBR4]1.018769 1.114777333 ENSOCUG00000006288 NINL ninein-like [Source:HGNCGL018741:571280-707680 Symbol;Acc:HGNC:29163]1.069699333 1.172298 ENSOCUG00000024922 - Uncharacterized9:13471126-13519011 protein [Source:UniProtKB/TrEMBL;Acc:G1TLI6]1.67106 1.831803333 ENSOCUG00000005877 GPR171 G protein-coupled14:44999873-45381998 receptor 1711.521439333 [Source:HGNC Symbol;Acc:HGNC:30057] 1.668537 ENSOCUG00000008159 CD27 CD27 molecule8:32506939-32513335 [Source:HGNC1.044983333 Symbol;Acc:HGNC:11922] 1.147123333 ENSOCUG00000026872 - Uncharacterized4:34945138-34985564 protein [Source:UniProtKB/TrEMBL;Acc:G1TZK4]1.179304667 1.295443333 ENSOCUG00000006673 A4GALT alpha 1,4-galactosyltransferaseGL018734:37873-38920 [Source:HGNC1.22804 Symbol;Acc:HGNC:18149] 1.351226667 ENSOCUG00000000107 MPPE1 metallophosphoesterase9:50021415-50234578 1 [Source:HGNC1.276583333 Symbol;Acc:HGNC:15988] 1.40466 ENSOCUG00000016447 KCNE3 potassium voltage-gated1:142149161-142149491 channel,1.789483333 Isk-related family, member 1.972577333 3 [Source:HGNC Symbol;Acc:HGNC:6243] ENSOCUG00000015307 SLC35F1 solute carrier12:107137605-107318461 family 35, member F11.726243 [Source:HGNC Symbol;Acc:HGNC:21483] 1.904588333 ENSOCUG00000027125 - Uncharacterized6:12357072-12480616 protein [Source:UniProtKB/TrEMBL;Acc:G1U0R8]1.497763333 1.652686667 ENSOCUG00000002364 TNFRSF9 tumor necrosis13:141911620-141939431 factor receptor superfamily,1.772371333 member 9 [Source:HGNC 1.956912 Symbol;Acc:HGNC:11924] ENSOCUG00000023913 APOBEC3H 4:84316205-843273281.506840333 1.667708333 ENSOCUG00000025805 SPATA9 spermatogenesis11:15305619-15347150 associated 9 [Source:HGNC1.269733333 Symbol;Acc:HGNC:22988] 1.40593 ENSOCUG00000008746 TRAIP TRAF interacting9:17356586-17380139 protein [Source:HGNC1.49766 Symbol;Acc:HGNC:30764] 1.664115 ENSOCUG00000014409 CCDC15 coiled-coil domain1:92223898-92308157 containing 151.501346667 [Source:HGNC Symbol;Acc:HGNC:25798] 1.66853

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ENSOCUG00000006424 CEP152 centrosomal17:23605082-23696090 protein 152kDa [Source:HGNC1.223000667 Symbol;Acc:HGNC:29298] 1.36013 ENSOCUG00000015922 RNASEL ribonucleaseGL019670:17593-25968 L (2',5'-oligoisoadenylate1.057307 synthetase-dependent) 1.176456333 [Source:HGNC Symbol;Acc:HGNC:10050] ENSOCUG00000010832 ASXL3 additional sex9:74976307-75135784 combs like transcriptional1.030386 regulator 3 [Source:HGNC 1.146569 Symbol;Acc:HGNC:29357] ENSOCUG00000006934 SLC23A1 solute carrier3:21622333-21629680 family 23 (ascorbic1.580533333 acid transporter), member 1.761186667 1 [Source:HGNC Symbol;Acc:HGNC:10974] ENSOCUG00000015805 NOX5 NADPH oxidase,GL018793:142675-174770 EF-hand calcium1.126387333 binding domain 5 [Source:HGNC 1.255428333 Symbol;Acc:HGNC:14874] ENSOCUG00000009422 C22orf23 chromosomeGL018972:207819-212076 22 open reading frame1.501451667 23 [Source:HGNC 1.678393333 Symbol;Acc:HGNC:18589] ENSOCUG00000005329 APOB Apolipoprotein2:170081705-170120499 B [Source:UniProtKB/Swiss-Prot;Acc:P17165]1.384161667 1.550476667 ENSOCUG00000012388 EMILIN3 elastin microfibrilGL018718:736909-741441 interfacer 3 [Source:HGNC1.000231 Symbol;Acc:HGNC:16123] 1.120431 ENSOCUG00000003108 TMEM44 transmembrane14:90428431-90464401 protein 44 [Source:HGNC1.285903 Symbol;Acc:HGNC:25120] 1.44132 ENSOCUG00000001384 RTTN rotatin [Source:HGNC9:110136912-110364886 Symbol;Acc:HGNC:18654]1.782336667 1.999046667 ENSOCUG00000006243 WDFY4 WDFY familyGL018819:594008-860542 member 4 [Source:HGNC1.553605333 Symbol;Acc:HGNC:29323] 1.74383 ENSOCUG00000010516 HIC2 hypermethylated21:5391896-5395263 in cancer 2 [Source:HGNC1.744113333 Symbol;Acc:HGNC:18595] 1.95923 ENSOCUG00000011794 NUP210L nucleoporin13:38395843-38525993 210kDa-like [Source:HGNC1.55046 Symbol;Acc:HGNC:29915] 1.746293333 ENSOCUG00000023239 ADORA3 Oryctolagus13:52645988-52733368 cuniculus adenosine1.058358333 A3 receptor (ADORA3), mRNA. 1.19215 [Source:RefSeq mRNA;Acc:NM_001082058] ENSOCUG00000005852 CHM-I Oryctolagus8:54111907-54137590 cuniculus chondromodulin-I1.102039333 precursor (CHM-I), 1.241370667 mRNA. [Source:RefSeq mRNA;Acc:NM_001082040] ENSOCUG00000002066 C11orf49 chromosome1:186291584-186537600 11 open reading frame1.710403333 49 [Source:HGNC Symbol;Acc:HGNC:28720] 1.92904 ENSOCUG00000029316 - Uncharacterized18:5311076-5350654 protein [Source:UniProtKB/TrEMBL;Acc:U3KN15]1.76516 1.992266667 ENSOCUG00000027937 - UncharacterizedAAGW02079214:17-38973 protein [Source:UniProtKB/TrEMBL;Acc:G1T4I1]1.521840667 1.71792 ENSOCUG00000013168 TSPAN33 tetraspanin 337:15416462-15439223 [Source:HGNC Symbol;Acc:HGNC:28743]1.178551333 1.331676667 ENSOCUG00000004912 GNAZ guanine nucleotideGL018810:108338-178840 binding protein1.425866667 (G protein), alpha z 1.611443333 polypeptide [Source:HGNC Symbol;Acc:HGNC:4395] ENSOCUG00000016650 DEPDC1B DEP domain11:76635166-76742728 containing 1B [Source:HGNC1.202167 Symbol;Acc:HGNC:24902] 1.358824333 ENSOCUG00000006156 WDPCP WD repeat containing2:122933724-123214422 planar cell1.335006667 polarity effector [Source:HGNC 1.511763333 Symbol;Acc:HGNC:28027] ENSOCUG00000004008 CNDP1 carnosineDraft dipeptidase9:114681592-114723824 1 (metallopeptidase1.601923333 M20 family) 1.815703333 [Source:HGNC Symbol;Acc:HGNC:20675] ENSOCUG00000021584 DOK3 docking protein3:58008131-58015240 3 [Source:HGNC1.286393333 Symbol;Acc:HGNC:24583] 1.46188 ENSOCUG00000029059 AQP10 aquaporin 1013:38255479-38257956 [Source:HGNC Symbol;Acc:HGNC:16029]1.087187667 1.235546667 ENSOCUG00000010502 SCN3B sodium channel,1:94456083-94473254 voltage-gated, 1.349173333type III, beta subunit [Source:HGNC 1.539816667 Symbol;Acc:HGNC:20665] ENSOCUG00000017841 OSBP2 oxysterol binding21:3240594-3383384 protein 2 [Source:HGNC1.52387 Symbol;Acc:HGNC:8504] 1.742736667 ENSOCUG00000015289 - 10:32184464-321850751.073659 1.228033333 ENSOCUG00000008800 ZWILCH zwilch kinetochore17:5857895-5896676 protein [Source:HGNC1.53491 Symbol;Acc:HGNC:25468] 1.758996667 ENSOCUG00000029485 - Uncharacterized2:95414467-95422933 protein [Source:UniProtKB/TrEMBL;Acc:U3KNC1]1.523393333 1.755943333 ENSOCUG00000012895 - Glutathione 12:42232462-42339504S-transferase [Source:UniProtKB/TrEMBL;Acc:G1T4A7]1.33346 1.537376667 ENSOCUG00000013958 MMAB methylmalonicGL018892:401614-418261 aciduria (cobalamin deficiency)1.64089 cblB type 1.897016667 [Source:HGNC Symbol;Acc:HGNC:19331] ENSOCUG00000004709 C1orf56 chromosome13:41125599-41127734 1 open reading frame1.635113333 56 [Source:HGNC Symbol;Acc:HGNC:26045] 1.89146 ENSOCUG00000002800 KIF12 kinesin familyGL018699:13497058-13503945 member 12 [Source:HGNC1.542354333 Symbol;Acc:HGNC:21495] 1.787346667 ENSOCUG00000004650 C9orf91 chromosomeGL018699:13038014-13062830 9 open reading frame 911.59399 [Source:HGNC 1.852166667Symbol;Acc:HGNC:24513] ENSOCUG00000017794 TULP2 tubby like proteinGL019028:90718-239810 2 [Source:HGNC 1.44155Symbol;Acc:HGNC:12424] 1.675513333 ENSOCUG00000022139 PGER8 UncharacterizedGL018750:547414-564974 protein [Source:UniProtKB/TrEMBL;Acc:G1TIG2]1.473792 1.717298667 ENSOCUG00000015222 SLC9C2 solute carrier13:905003-1065458 family 9, member C21.274817 (putative) [Source:HGNC 1.485727667 Symbol;Acc:HGNC:28664] ENSOCUG00000002773 C3orf67 chromosome9:25491593-25770715 3 open reading frame1.545733333 67 [Source:HGNC Symbol;Acc:HGNC:24763] 1.80529 ENSOCUG00000020999 - X:26770295-267712001.518713333 1.77417 ENSOCUG00000009004 - 15:26875961-268767561.198602667 1.400719 ENSOCUG00000009504 CD80 Oryctolagus14:99215920-99248003 cuniculus CD80 molecule1.316676667 (CD80), mRNA. [Source:RefSeq 1.54023 mRNA;Acc:NM_001082663] ENSOCUG00000028997 ZNF793 zinc finger protein5:1281977-1286172 793 [Source:HGNC1.136632667 Symbol;Acc:HGNC:33115] 1.330551 ENSOCUG00000017473 FAM216B family with 8:52268562-52278265sequence similarity1.113050667 216, member B [Source:HGNC 1.303163333 Symbol;Acc:HGNC:26883] ENSOCUG00000007550 MIS18BP1 MIS18 binding17:64505230-64624020 protein 1 [Source:HGNC1.407553333 Symbol;Acc:HGNC:20190] 1.648983333 ENSOCUG00000029631 - Uncharacterized1:182294486-182298954 protein [Source:UniProtKB/TrEMBL;Acc:U3KP57]1.046662667 1.226878 ENSOCUG00000017867 FRAS1 Fraser extracellular15:71847427-72347948 matrix complex 1.33846subunit 1 [Source:HGNC 1.56947 Symbol;Acc:HGNC:19185] ENSOCUG00000011550 CD86 Oryctolagus14:96928918-97000745 cuniculus CD86 molecule1.61045 (CD86), mRNA. 1.893673333 [Source:RefSeq mRNA;Acc:NM_001082208] ENSOCUG00000027402 - Uncharacterized16:68523203-68540052 protein [Source:UniProtKB/TrEMBL;Acc:G1U572]1.413826667 1.664436667 ENSOCUG00000011222 KIAA1257 KIAA1257 [Source:HGNC9:8036613-8055807 Symbol;Acc:HGNC:29231]1.131511333 1.333956333

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ENSOCUG00000023896 E2F2 E2F transcription13:129694181-129720484 factor 2 [Source:HGNC1.119333 Symbol;Acc:HGNC:3114] 1.322905 ENSOCUG00000008990 RLTPR RGD motif,5:23207880-23220225 leucine rich repeats,1.278285333 tropomodulin domain 1.517623333 and proline-rich containing [Source:HGNC Symbol;Acc:HGNC:27089] ENSOCUG00000015956 LRMP lymphoid-restricted8:14979232-15023321 membrane protein1.292884 [Source:HGNC 1.538148667 Symbol;Acc:HGNC:6690] ENSOCUG00000026154 - UncharacterizedGL019404:11933-18261 protein [Source:UniProtKB/TrEMBL;Acc:G1TIJ5]1.422733 1.696416667 ENSOCUG00000008012 STMN1 Stathmin [Source:UniProtKB/TrEMBL;Acc:G1SU98]3:69407538-694083301.152303333 1.377083333 ENSOCUG00000001497 FABP7 fatty acid binding12:111910122-111915735 protein 7, brain1.084885667 [Source:HGNC Symbol;Acc:HGNC:3562] 1.297827667 ENSOCUG00000005237 PCDH17 protocadherin8:58807440-58904181 17 [Source:HGNC1.005320667 Symbol;Acc:HGNC:14267] 1.203901 ENSOCUG00000011186 SRPX2 sushi-repeatX:88643996-88738279 containing protein, X-linked1.41449 2 [Source:HGNC 1.694673333 Symbol;Acc:HGNC:30668] ENSOCUG00000005836 NRG1 neuregulin 12:74984999-75233685 [Source:HGNC Symbol;Acc:HGNC:7997]1.637891 1.962863333 ENSOCUG00000009195 CLEC4E C-type lectin8:33490791-33497808 domain family 4, 1.077794667member E [Source:HGNC 1.291786667 Symbol;Acc:HGNC:14555] ENSOCUG00000006448 ABCB9 ATP-bindingGL019055:6483-44124 cassette, sub-family1.161013667 B (MDR/TAP), member 1.391693333 9 [Source:HGNC Symbol;Acc:HGNC:50] ENSOCUG00000025119 RELT RELT tumor1:143095559-143103195 necrosis factor receptor1.064371333 [Source:HGNC Symbol;Acc:HGNC:13764] 1.277127667 ENSOCUG00000000962 ORC1 origin recognition13:114334046-114360831 complex, subunit1.057558 1 [Source:HGNC 1.270413333Symbol;Acc:HGNC:8487] ENSOCUG00000024410 - Uncharacterized9:59598268-59598706 protein [Source:UniProtKB/TrEMBL;Acc:G1TZZ3]1.057873333 1.270854333 ENSOCUG00000003187 REM1 RAS (RAD 4:7698033-7708532and GEM)-like GTP-binding1.47972 1 [Source:HGNC 1.779926667 Symbol;Acc:HGNC:15922] ENSOCUG00000001296 HES2 hes family bHLH13:143198142-143201800 transcription 1.637657667factor 2 [Source:HGNC Symbol;Acc:HGNC:16005] 1.97018 ENSOCUG00000003660 - Uncharacterized9:14545404-14546514 protein [Source:UniProtKB/TrEMBL;Acc:G1SK57]1.318549333 1.592103333 ENSOCUG00000024948 - Uncharacterized3:100866485-100870135 protein [Source:UniProtKB/TrEMBL;Acc:G1U6R6]1.57497 1.906936667 ENSOCUG00000023002 - UncharacterizedGL018825:557671-582456 protein [Source:UniProtKB/TrEMBL;Acc:G1U454]1.463029333 1.777183333 ENSOCUG00000021631 SNORA53 Small nucleolar4:77885029-77891468 RNA SNORA531.177456667 [Source:RFAM;Acc:RF00563] 1.431936667 ENSOCUG00000016005 EXO5 exonuclease13:126036744-126044447 5 [Source:HGNC Symbol;Acc:HGNC:26115]1.609893333 1.958686667 ENSOCUG00000003763 PTPN22 protein tyrosine13:50338598-50395878 phosphatase, non-receptor1.151777667 type 22 (lymphoid) 1.404081667 [Source:HGNC Symbol;Acc:HGNC:9652] ENSOCUG00000007289 PNMA1 paraneoplasticDraft20:31299545-31300604 Ma antigen 1 [Source:HGNC1.189724333 Symbol;Acc:HGNC:9158] 1.4517 ENSOCUG00000022039 AKAP17A A kinase (PRKA)X:67976726-67988069 anchor protein1.337935667 17A [Source:HGNC 1.635383333Symbol;Acc:HGNC:18783] ENSOCUG00000000979 MAP4K1 mitogen-activated5:2565159-2579881 protein kinase1.378455333 kinase kinase kinase 1 [Source:HGNC 1.68624 Symbol;Acc:HGNC:6863] ENSOCUG00000022191 - 4:74386162-745106911.157262333 1.42247 ENSOCUG00000003084 CPB1 carboxypeptidase14:42618253-42651397 B1 (tissue) [Source:HGNC1.341457333 Symbol;Acc:HGNC:2299] 1.657464333 ENSOCUG00000003511 GPR85 G protein-coupled7:32363685-32364798 receptor 85 [Source:HGNC1.508550667 Symbol;Acc:HGNC:4536] 1.865723333 ENSOCUG00000016081 - UncharacterizedGL018831:107785-109482 protein [Source:UniProtKB/TrEMBL;Acc:G1TAV5]1.582193333 1.958123333 ENSOCUG00000022986 CCDC163P 13:121142866-1211456051.242323333 1.537636667 ENSOCUG00000007995 - 17:28942783-289448461.611811 1.995383333 ENSOCUG00000001107 ARHGAP4 Rho GTPaseGL018816:520319-537985 activating protein 1.5364033334 [Source:HGNC Symbol;Acc:HGNC:674] 1.90582 ENSOCUG00000015540 ADAT1 adenosine deaminase,5:30237585-30262189 tRNA-specific1.533526667 1 [Source:HGNC 1.903053333 Symbol;Acc:HGNC:228] ENSOCUG00000005151 KIAA0895 KIAA0895 [Source:HGNC10:19832512-20175622 Symbol;Acc:HGNC:22206]1.012174 1.258093333 ENSOCUG00000000723 TMEM55A transmembrane3:106596017-106667024 protein 55A [Source:HGNC1.240775 Symbol;Acc:HGNC:25452] 1.542344 ENSOCUG00000011397 TREM1 triggering receptor12:30991672-30999674 expressed on1.474564667 myeloid cells 1 [Source:HGNC 1.84872 Symbol;Acc:HGNC:17760] ENSOCUG00000012109 - Uncharacterized4:84078836-84081799 protein [Source:UniProtKB/TrEMBL;Acc:G1TWQ8]1.41939 1.78387 ENSOCUG00000022434 CDCA3 cell division8:32864290-32874163 cycle associated 3 1.177577333[Source:HGNC Symbol;Acc:HGNC:14624] 1.49314 ENSOCUG00000017181 PKMYT1 protein kinase,GL018828:225935-229543 membrane associated1.547913333 tyrosine/threonine 1 [Source:HGNC 1.96551 Symbol;Acc:HGNC:29650] ENSOCUG00000000953 RMI2 RecQ mediated6:4885172-4891420 genome instability1.406293333 2 [Source:HGNC Symbol;Acc:HGNC:28349] 1.792265333 ENSOCUG00000010195 ZC2HC1C zinc finger, 20:30048184-30056236C2HC-type containing1.162159667 1C [Source:HGNC 1.481306667Symbol;Acc:HGNC:20354] ENSOCUG00000003116 - UncharacterizedGL018758:1545535-1650995 protein [Source:UniProtKB/TrEMBL;Acc:G1U2Y9]1.267328667 1.619039333 ENSOCUG00000001719 DIAPH3 diaphanous-related8:61106057-61648921 formin 3 [Source:HGNC1.176409 Symbol;Acc:HGNC:15480] 1.504616667 ENSOCUG00000014665 REPS2 RALBP1 associatedX:2830155-3080423 Eps domain1.104039333 containing 2 [Source:HGNC 1.413648 Symbol;Acc:HGNC:9963] ENSOCUG00000013772 TUBD1 tubulin, delta19:28435231-28625298 1 [Source:HGNC 1.398165333Symbol;Acc:HGNC:16811] 1.792123333 ENSOCUG00000011170 HJURP Holliday junctionGL018736:1329771-1340172 recognition protein1.47631 [Source:HGNC Symbol;Acc:HGNC:25444] 1.899116667 ENSOCUG00000010001 HSF4 heat shock transcription5:22779286-22831282 factor 41.373886667 [Source:HGNC Symbol;Acc:HGNC:5227] 1.772753333 ENSOCUG00000009913 - Uncharacterized6:11740941-11814124 protein [Source:UniProtKB/TrEMBL;Acc:G1SY60]1.086172667 1.40233 ENSOCUG00000008742 - UncharacterizedGL019398:39381-40373 protein [Source:UniProtKB/TrEMBL;Acc:G1U2D6]1.44797 1.872521333 ENSOCUG00000024128 - Uncharacterized5:22494668-22498303 protein [Source:UniProtKB/TrEMBL;Acc:G1SF18]1.173539667 1.520716667

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ENSOCUG00000006860 GLDN gliomedin [Source:HGNC17:21122357-21179871 Symbol;Acc:HGNC:29514]1.359439333 1.76535 ENSOCUG00000013497 ULK4 unc-51 like 9:2186331-2340597kinase 4 [Source:HGNC1.204866667 Symbol;Acc:HGNC:15784] 1.56592 ENSOCUG00000024762 CKS2 CDC28 proteinX:71420756-71420996 kinase regulatory1.061476667 subunit 2 [Source:HGNC 1.380976667 Symbol;Acc:HGNC:2000] ENSOCUG00000011279 1-Mar membrane-associatedGL018701:6328736-6695794 ring finger (C3HC4)1.145148 1, E3 ubiquitin 1.499183333 protein ligase [Source:HGNC Symbol;Acc:HGNC:26077] ENSOCUG00000023082 ABHD16B abhydrolaseGL019070:7859-67371 domain containing1.489624333 16B [Source:HGNC Symbol;Acc:HGNC:16128] 1.964726667 ENSOCUG00000029609 - chromosome12:12217055-12220770 6 open reading frame 2291.03397 [Source:HGNC 1.365213333 Symbol;Acc:HGNC:49394] ENSOCUG00000013801 SHCBP1 SHC SH2-domainGL018743:1374001-1414639 binding protein1.249870333 1 [Source:HGNC Symbol;Acc:HGNC:29547] 1.65527 ENSOCUG00000008964 HOXD10 homeobox D107:115676650-115681796 [Source:HGNC1.154009333 Symbol;Acc:HGNC:5133] 1.536043333 ENSOCUG00000001921 KIAA0825 KIAA0825 [Source:HGNC11:13852074-14224463 Symbol;Acc:HGNC:28532]1.32547 1.770696667 ENSOCUG00000009932 ESCO2 establishment2:41849727-41893015 of sister chromatid cohesion1.20658 N-acetyltransferase 1.612066667 2 [Source:HGNC Symbol;Acc:HGNC:27230] ENSOCUG00000017310 SLC6A2 solute carrier5:11873712-11917538 family 6 (neurotransmitter1.140333 transporter), member 1.530143 2 [Source:HGNC Symbol;Acc:HGNC:11048] ENSOCUG00000009777 GAREML GRB2 associated,2:159715900-159720181 regulator of MAPK1-like1.178185333 [Source:HGNC 1.585603333 Symbol;Acc:HGNC:27172] ENSOCUG00000012527 SLC26A7 solute carrier3:106874455-107015659 family 26 (anion exchanger),1.227177667 member 7 [Source:HGNC 1.654993333 Symbol;Acc:HGNC:14467] ENSOCUG00000009337 - GL018710:823239-8692901.268084667 1.712876667 ENSOCUG00000025123 GCNT4 glucosaminylGL018859:445407-446733 (N-acetyl) transferase1.021546667 4, core 2 [Source:HGNC 1.38874 Symbol;Acc:HGNC:17973] ENSOCUG00000013312 KCNH4 potassium voltage-gated19:42985070-42997952 channel, subfamily1.330729 H (eag-related), 1.820417 member 4 [Source:HGNC Symbol;Acc:HGNC:6253] ENSOCUG00000023559 - septin 1 [Source:HGNCGL018752:1814848-1818081 Symbol;Acc:HGNC:2879]1.129202 1.545721667 ENSOCUG00000004688 PKHD1L1 polycystic kidney3:124888007-125070545 and hepatic disease1.326523333 1 (autosomal recessive)-like 1.83736 1 [Source:HGNC Symbol;Acc:HGNC:20313] ENSOCUG00000017111 - UncharacterizedX:48850994-48981065 protein [Source:UniProtKB/TrEMBL;Acc:G1TD22]1.368293667 1.896906667 ENSOCUG00000012007 PRR5L proline rich 1:175680707-1757446245 like [Source:HGNC Symbol;Acc:HGNC:25878]1.40859 1.962656667 ENSOCUG00000025809 RTN4RL2 reticulon 4 receptor-like1:190547230-190560766 2 [Source:HGNC1.416883333 Symbol;Acc:HGNC:23053] 1.975623333 ENSOCUG00000005974 LINGO1 leucine rich GL018768:549333-564457repeat and Ig domain1.127515333 containing 1 [Source:HGNC 1.572551333 Symbol;Acc:HGNC:21205] ENSOCUG00000016509 - complementDraft16:74287791-74347589 factor H [Source:HGNC1.398379333 Symbol;Acc:HGNC:4883] 1.954642667 ENSOCUG00000007327 CNTNAP1 contactin associated19:43410851-43423128 protein 1 [Source:HGNC1.010277667 Symbol;Acc:HGNC:8011] 1.413116667 ENSOCUG00000027921 - X:61082266-610831631.136238333 1.591596667 ENSOCUG00000008771 IL1A Oryctolagus2:97559305-97569595 cuniculus interleukin1.192904667 1, alpha (IL1A), mRNA. 1.671163333 [Source:RefSeq mRNA;Acc:NM_001101684] ENSOCUG00000024009 - UncharacterizedGL018719:2323166-2611649 protein [Source:UniProtKB/TrEMBL;Acc:G1TLZ6]1.018469667 1.429852333 ENSOCUG00000001717 SKAP1 src kinase associated19:38917125-39223168 phosphoprotein1.191262 1 [Source:HGNC 1.678249333 Symbol;Acc:HGNC:15605] ENSOCUG00000025070 CCDC114 coiled-coil domainGL019039:7222-8957 containing 1141.314703667 [Source:HGNC Symbol;Acc:HGNC:26560] 1.852398333 ENSOCUG00000005819 ZAP70 zeta-chain (TCR)2:94409897-94435968 associated protein1.058933 kinase 70kDa [Source:HGNC 1.494141 Symbol;Acc:HGNC:12858] ENSOCUG00000013763 DLGAP1 discs, large (Drosophila)9:58026714-58571743 homolog-associated1.405106667 protein 1 [Source:HGNC 1.98446 Symbol;Acc:HGNC:2905] ENSOCUG00000023708 - Uncharacterized5:22397056-22418991 protein [Source:UniProtKB/TrEMBL;Acc:G1T6L1]1.313515667 1.871943333 ENSOCUG00000005122 TMEM125 transmembrane13:123389989-123390649 protein 125 [Source:HGNC1.372473333 Symbol;Acc:HGNC:28275] 1.956903333 ENSOCUG00000001561 TNFRSF17 tumor necrosis6:5381482-5386838 factor receptor superfamily,1.395893333 member 17 1.993968667 [Source:HGNC Symbol;Acc:HGNC:11913] ENSOCUG00000005503 SPDL1 spindle apparatus3:51012212-51032263 coiled-coil protein 11.3128 [Source:HGNC Symbol;Acc:HGNC:26010] 1.88209 ENSOCUG00000014013 CSPG5 chondroitin 9:15492258-15529139sulfate proteoglycan1.293433333 5 (neuroglycan C) [Source:HGNC 1.85446 Symbol;Acc:HGNC:2467] ENSOCUG00000010292 EFHC2 EF-hand domainX:29594144-29779641 (C-terminal) containing1.353686667 2 [Source:HGNC 1.944073333 Symbol;Acc:HGNC:26233] ENSOCUG00000029428 GIMAP2 GTPase, IMAPGL018806:185449-189560 family member 2 [Source:HGNC1.081693 Symbol;Acc:HGNC:21789] 1.553729667 ENSOCUG00000011218 - Uncharacterized9:8011531-8030523 protein [Source:UniProtKB/TrEMBL;Acc:G1T0V5]1.384044667 1.990406333 ENSOCUG00000005865 SCUBE1 signal peptide,GL018988:129-108057 CUB domain, EGF-like1.008741667 1 [Source:HGNC 1.452043333 Symbol;Acc:HGNC:13441] ENSOCUG00000021638 AHRR aryl-hydrocarbonGL018897:281751-308157 receptor repressor1.247943333 [Source:HGNC Symbol;Acc:HGNC:346] 1.800404 ENSOCUG00000005728 GPRIN2 G protein regulated18:8825767-8827147 inducer of neurite1.175014333 outgrowth 2 [Source:HGNC 1.727546667 Symbol;Acc:HGNC:23730] ENSOCUG00000029731 - Uncharacterized12:23145142-23186082 protein [Source:UniProtKB/TrEMBL;Acc:U3KMS9]1.264089 1.86183 ENSOCUG00000021541 SHMT1 Serine hydroxymethyltransferase,GL018817:799782-8223871.146305667 cytosolic [Source:UniProtKB/Swiss-Prot;Acc:P07511] 1.688793333 ENSOCUG00000025874 - UncharacterizedAAGW02079658:71615-72098 protein [Source:UniProtKB/TrEMBL;Acc:G1TWX4]1.015716667 1.52473 ENSOCUG00000005217 TSPAN1 tetraspanin 113:120338496-120342894 [Source:HGNC Symbol;Acc:HGNC:20657]1.005655 1.512343 ENSOCUG00000012464 CD6 CD6 molecule1:193593327-193631770 [Source:HGNC Symbol;Acc:HGNC:1691]1.046814 1.583948 ENSOCUG00000026358 STRA6 stimulated byGL019108:112562-127798 retinoic acid 6 [Source:HGNC1.193865 Symbol;Acc:HGNC:30650] 1.811353333 ENSOCUG00000001823 - Uncharacterized13:128261062-128296931 protein [Source:UniProtKB/TrEMBL;Acc:G1SG71]1.148467 1.7685 ENSOCUG00000010409 RBM11 RNA binding14:142004497-142025226 motif protein 11 [Source:HGNC1.140026667 Symbol;Acc:HGNC:9897] 1.76192

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ENSOCUG00000028059 NLRC3 NLR family,GL018828:763089-777861 CARD domain containing1.271398333 3 [Source:HGNC 1.987536667 Symbol;Acc:HGNC:29889] ENSOCUG00000009374 IRF4 interferon regulatoryGL018747:1065501-1089436 factor 4 [Source:HGNC1.216388667 Symbol;Acc:HGNC:6119] 1.910226667 ENSOCUG00000015747 GINS1 GINS complexGL018741:725205-763310 subunit 1 (Psf1 1.233986667homolog) [Source:HGNC Symbol;Acc:HGNC:28980] 1.93932 ENSOCUG00000011838 - Alveolar macrophage15:76296315-76299497 chemotactic1.199156667 factor [Source:UniProtKB/Swiss-Prot;Acc:P82535] 1.885876667 ENSOCUG00000016029 IQCD IQ motif containing21:8882062-8890045 D [Source:HGNC1.252833333 Symbol;Acc:HGNC:25168] 1.982513333 ENSOCUG00000022194 - Uncharacterized16:66129528-66142649 protein [Source:UniProtKB/TrEMBL;Acc:G1TN78]1.161373 1.854923333 ENSOCUG00000013787 OGDHL oxoglutarate18:5815210-5836112 dehydrogenase-like1.044362667 [Source:HGNC Symbol;Acc:HGNC:25590] 1.675459 ENSOCUG00000011143 FOSL1 FOS-like antigen1:193697423-193702395 1 [Source:HGNC1.079160333 Symbol;Acc:HGNC:13718] 1.733734333 ENSOCUG00000008474 CD2 CD2 molecule13:47551879-47565052 [Source:HGNC Symbol;Acc:HGNC:1639]1.123117333 1.809496667 ENSOCUG00000026993 - UncharacterizedGL018806:571147-575309 protein [Source:UniProtKB/TrEMBL;Acc:G1TVR4]1.127106333 1.816736667 ENSOCUG00000001627 SLC6A11 solute carrier9:12745130-12860770 family 6 (neurotransmitter1.035366333 transporter), member 1.684471333 11 [Source:HGNC Symbol;Acc:HGNC:11044] ENSOCUG00000025701 CRHR1 Oryctolagus19:46187259-46225746 cuniculus corticotropin1.050968333 releasing hormone 1.710851333 receptor 1 (CRHR1), mRNA. [Source:RefSeq mRNA;Acc:NM_001163115] ENSOCUG00000014120 - Uncharacterized20:30384589-30398551 protein [Source:UniProtKB/TrEMBL;Acc:G1T6R8]1.055867333 1.72545 ENSOCUG00000011479 SOX5 SRY (sex determining8:16189845-16615169 region Y)-box1.033016667 5 [Source:HGNC 1.718873333 Symbol;Acc:HGNC:11201] ENSOCUG00000029266 - Uncharacterized12:104645991-104648659 protein [Source:UniProtKB/TrEMBL;Acc:U3KPD6]1.006967967 1.686644333 ENSOCUG00000002337 PRR11 proline rich 19:29119098-2913902611 [Source:HGNC 1.018207667Symbol;Acc:HGNC:25619] 1.707209667 ENSOCUG00000006899 KIF18B kinesin family19:45381543-45392253 member 18B [Source:HGNC1.115417667 Symbol;Acc:HGNC:27102] 1.963969667 ENSOCUG00000009679 THEM5 thioesterase 13:40342547-40352042superfamily member 5 [Source:HGNC1.02877 Symbol;Acc:HGNC:26755] 1.845956667 ENSOCUG00000022805 - Uncharacterized13:41805043-41821924 protein [Source:UniProtKB/TrEMBL;Acc:G1SLG0]5.95437 9.006656667 ENSOCUG00000012215 TRPV3 transient receptor19:14879082-14906816 potential cation5.985993333 channel, subfamily V, 9.458423333 member 3 [Source:HGNC Symbol;Acc:HGNC:18084] ENSOCUG00000003246 SULF1 sulfatase 1 [Source:HGNC3:85532881-85617040 Symbol;Acc:HGNC:20391]5.651036667 9.067006667 ENSOCUG00000002848 CCL5 chemokine (C-C19:24922477-24932917 motif) ligand 5 [Source:HGNC5.793343 Symbol;Acc:HGNC:10632] 9.340006667 ENSOCUG00000003500 FAM84B familyDraft with 3:142278450-142279374sequence similarity5.610746667 84, member B [Source:HGNC 9.333996667 Symbol;Acc:HGNC:24166] ENSOCUG00000002601 OTUB2 OTU deubiquitinase,GL018883:31092-70123 ubiquitin aldehyde5.714233333 binding 2 [Source:HGNC 9.557743333 Symbol;Acc:HGNC:20351] ENSOCUG00000008791 SNAPC5 small nuclear17:5902213-5903486 RNA activating complex,5.354796667 polypeptide 5, 9.26953666719kDa [Source:HGNC Symbol;Acc:HGNC:15484] ENSOCUG00000005133 MKI67 marker of proliferationGL018726:2310834-2336198 Ki-67 [Source:HGNC5.186306667 Symbol;Acc:HGNC:7107] 9.9445 ENSOCUG00000025315 FAM26D family with 12:104750735-104836786sequence similarity 26, member15.7287 D [Source:HGNC 45.7133 Symbol;Acc:HGNC:21094] ENSOCUG00000015603 KRT40 keratin 40 [Source:HGNC19:42027272-42032696 Symbol;Acc:HGNC:26707]11.44153333 22.71786667 ENSOCUG00000027223 - Uncharacterized2:98143892-98256733 protein [Source:UniProtKB/TrEMBL;Acc:G1TRN9]2.05678 11.26439333 ENSOCUG00000004116 LYG2 lysozyme G-like2:92990201-92994384 2 [Source:HGNC7.713843333 Symbol;Acc:HGNC:29615] 25.49601 ENSOCUG00000017110 KRTAP27-1 keratin associated14:159936841-159937465 protein 27-1 [Source:HGNC7.411 Symbol;Acc:HGNC:33864] 25.72763333 ENSOCUG00000029401 - UncharacterizedX:41841052-42003181 protein [Source:UniProtKB/TrEMBL;Acc:U3KP07]4.804163333 8.2285 ENSOCUG00000006225 PROSER2 proline and 16:16465844-16515209serine rich 2 [Source:HGNC4.910903333 Symbol;Acc:HGNC:23728] 8.772136667 ENSOCUG00000029190 PLAC8 placenta-specific15:67235445-67255786 8 [Source:HGNC4.854729333 Symbol;Acc:HGNC:19254] 8.691393 ENSOCUG00000003263 SLCO5A1 solute carrier3:85627681-85804636 organic anion transporter4.324526667 family, member 8.752366667 5A1 [Source:HGNC Symbol;Acc:HGNC:19046] ENSOCUG00000025113 MYCL v-myc avian13:126607134-126613913 myelocytomatosis viral4.24159 oncogene lung carcinoma 8.749516667 derived homolog [Source:HGNC Symbol;Acc:HGNC:7555] ENSOCUG00000011992 - Uncharacterized19:42151610-42226613 protein [Source:UniProtKB/TrEMBL;Acc:G1SWV0]4.151636667 8.669606667 ENSOCUG00000023492 - Uncharacterized19:42284584-42284890 protein [Source:UniProtKB/TrEMBL;Acc:G1T814]63.5601 166.5076 ENSOCUG00000013493 SLC7A1 solute carrierGL018735:2510296-2536658 family 7 (cationic amino4.99782 acid transporter, 7.101203333 y+ system), member 1 [Source:HGNC Symbol;Acc:HGNC:11057] ENSOCUG00000024278 - UncharacterizedGL018806:368160-369027 protein [Source:UniProtKB/TrEMBL;Acc:G1U237]4.789573333 7.285116667 ENSOCUG00000012503 METTL21B methyltransferaseGL018714:831954-941468 like 21B [Source:HGNC4.845316667 Symbol;Acc:HGNC:24936] 7.644526667 ENSOCUG00000005252 NCMAP noncompact13:128851140-128864478 myelin associated protein4.513253333 [Source:HGNC 7.597543333Symbol;Acc:HGNC:29332] ENSOCUG00000029712 - Uncharacterized11:80303308-80306767 protein [Source:UniProtKB/TrEMBL;Acc:U3KN64]4.349636667 7.549756667 ENSOCUG00000023107 - Uncharacterized14:71120-72489 protein [Source:UniProtKB/TrEMBL;Acc:G1SEE8]4.540556667 7.910716667 ENSOCUG00000001515 CCL19 chemokine (C-C1:19132433-19133670 motif) ligand 194.020616667 [Source:HGNC Symbol;Acc:HGNC:10617] 7.806293333 ENSOCUG00000007886 FAM49A family with 2:165494498-165569587sequence similarity 49, member9.38582 A [Source:HGNC 17.37606667 Symbol;Acc:HGNC:25373] ENSOCUG00000013779 FOXN1 forkhead box19:19612113-19638332 N1 [Source:HGNC15.82536667 Symbol;Acc:HGNC:12765] 31.14026667 ENSOCUG00000011944 ENPP6 ectonucleotide2:61414552-61540392 pyrophosphatase/phosphodiesterase1.64716 6 [Source:HGNC 9.255593333 Symbol;Acc:HGNC:23409] ENSOCUG00000000663 ACTBL2 actin, beta-like11:73382820-73383951 2 [Source:HGNC5.587856667 Symbol;Acc:HGNC:17780] 20.85736 ENSOCUG00000007938 ALDH1A3 aldehyde dehydrogenaseGL019481:20-32016 1 family,8.146093333 member A3 [Source:HGNC 16.06287667 Symbol;Acc:HGNC:409]

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ENSOCUG00000014720 LYG1 lysozyme G-like2:92938411-92947509 1 [Source:HGNC Symbol;Acc:HGNC:27014]1.68771 8.731236667 ENSOCUG00000019393 SNORA74 Small nucleolar3:21543197-21543399 RNA SNORA7432.88742333 [Source:RFAM;Acc:RF00090] 67.20363333 ENSOCUG00000000560 HEYL hes-related family13:126885591-126893820 bHLH transcription8.5672 factor with YRPW motif-like 15.9607 [Source:HGNC Symbol;Acc:HGNC:4882] ENSOCUG00000023667 - Uncharacterized8:37813322-37833951 protein [Source:UniProtKB/TrEMBL;Acc:G1TR95]0.944613333 1.00E-05 ENSOCUG00000022130 - GL018833:96999-972030.89434 1.00E-05 ENSOCUG00000023186 - 7:156782219-1567830750.87308 1.00E-05 ENSOCUG00000021709 - bolA familyGL018775:654117-765990 member 3 [Source:HGNC0.763176667 Symbol;Acc:HGNC:24415] 1.00E-05 ENSOCUG00000029558 - Uncharacterized12:155088030-155089092 protein [Source:UniProtKB/TrEMBL;Acc:U3KML9]0.684567667 1.00E-05 ENSOCUG00000025328 UBA52 1:37165357-376208250.643123333 1.00E-05 ENSOCUG00000026970 - Uncharacterized8:34375399-34379927 protein [Source:UniProtKB/TrEMBL;Acc:G1U5H9]0.623779 1.00E-05 ENSOCUG00000026579 - UncharacterizedAAGW02080791:38038-38515 protein [Source:UniProtKB/TrEMBL;Acc:G1T1F5]0.606823667 1.00E-05 ENSOCUG00000028681 7SK 7SK RNA [Source:RFAM;Acc:RF00100]X:7093496-74066750.578166667 1.00E-05 ENSOCUG00000022523 - UncharacterizedAAGW02081973:5465-5936 protein [Source:UniProtKB/TrEMBL;Acc:G1TRW6]0.571673333 1.00E-05 ENSOCUG00000020815 7SK 7SK RNA [Source:RFAM;Acc:RF00100]9:49438549-498010480.533766667 1.00E-05 ENSOCUG00000001512 FAM159B family with 11:80898097-80922958sequence similarity0.533035667 159, member B [Source:HGNC 1.00E-05 Symbol;Acc:HGNC:34236] ENSOCUG00000021322 - 13:33654674-336556880.523463333 1.00E-05 ENSOCUG00000020668 7SK 7SK RNA [Source:RFAM;Acc:RF00100]15:16524265-168816060.511986667 1.00E-05 ENSOCUG00000022847 - 14:13317167-133175090.507146667 1.00E-05 ENSOCUG00000026536 - Uncharacterized2:98481563-98539867 protein [Source:UniProtKB/TrEMBL;Acc:G1TJR8]0.49603 1.00E-05 ENSOCUG00000023760 - GL018718:1246104-12464480.49232 1.00E-05 ENSOCUG00000027512 - Uncharacterized10:21473873-21534045 protein [Source:UniProtKB/TrEMBL;Acc:G1TJX3]0.484130667 1.00E-05 ENSOCUG00000005978 - 18:18387944-183884770.483986667 1.00E-05 ENSOCUG00000013247 - Draft14:87023625-870239940.473526667 1.00E-05 ENSOCUG00000021652 PIRT phosphoinositide-interacting19:8765260-8765668 regulator0.448626667 of transient receptor 1.00E-05 potential channels [Source:HGNC Symbol;Acc:HGNC:37239] ENSOCUG00000011028 IL25 interleukin 2517:43569195-43571703 [Source:HGNC Symbol;Acc:HGNC:13765]0.432347333 1.00E-05 ENSOCUG00000028653 SCARNA6 Small Cajal GL018736:750881-793567body specific RNA 6 [Source:RFAM;Acc:RF00478]0.42964 1.00E-05 ENSOCUG00000002404 - 3:14795226-14928401 0.42898 1.00E-05 ENSOCUG00000000243 INS OryctolagusAAGW02082940:1285-2082 cuniculus insulin (INS),0.427803333 mRNA. [Source:RefSeq 1.00E-05 mRNA;Acc:NM_001082335] ENSOCUG00000027830 - 15:61566357-616250500.415193333 1.00E-05 ENSOCUG00000025571 - UncharacterizedGL018852:233800-485796 protein [Source:UniProtKB/TrEMBL;Acc:G1U712]0.404940333 1.00E-05 ENSOCUG00000010595 - Uncharacterized2:12336513-12337256 protein [Source:UniProtKB/TrEMBL;Acc:G1TNX8]0.40432 1.00E-05 ENSOCUG00000024674 - Uncharacterized12:8583808-8584169 protein [Source:UniProtKB/TrEMBL;Acc:G1THV4]0.40309 1.00E-05 ENSOCUG00000023984 - GL018907:316644-3169170.394426667 1.00E-05 ENSOCUG00000008927 - 13:98972400-989727960.394153333 1.00E-05 ENSOCUG00000028083 PPY Pancreatic hormone19:44327821-44328727 [Source:UniProtKB/Swiss-Prot;Acc:P41336]0.390671667 1.00E-05 ENSOCUG00000025754 7SK 7SK RNA [Source:RFAM;Acc:RF00100]17:55213993-554796220.388753333 1.00E-05 ENSOCUG00000026642 TRBV3-1 T cell receptorGL018758:1219791-1220082 beta variable 3-1 [Source:HGNC0.38512 Symbol;Acc:HGNC:12212] 1.00E-05 ENSOCUG00000011105 - Uncharacterized14:119161162-119161913 protein [Source:UniProtKB/TrEMBL;Acc:G1T0N1]0.380123333 1.00E-05 ENSOCUG00000023249 7SK 7SK RNA [Source:RFAM;Acc:RF00100]6:24320681-243209430.375046667 1.00E-05 ENSOCUG00000023199 - GL018703:6755747-67561060.357308667 1.00E-05 ENSOCUG00000023111 - UncharacterizedX:12240006-12240567 protein [Source:UniProtKB/TrEMBL;Acc:G1U611]0.353974667 1.00E-05 ENSOCUG00000014272 IL19 interleukin 1916:65519826-65525648 [Source:HGNC Symbol;Acc:HGNC:5990]0.35326 1.00E-05 ENSOCUG00000019862 7SK 7SK RNA [Source:RFAM;Acc:RF00100]12:26284727-262850470.352036667 1.00E-05 ENSOCUG00000027421 - Uncharacterized1:71421046-71421388 protein [Source:UniProtKB/TrEMBL;Acc:G1U0P0]0.34825 1.00E-05 ENSOCUG00000024235 - 17:64321898-643223620.347770667 1.00E-05 ENSOCUG00000019601 RNase_MRPRNase MRP1:18269867-18270142 [Source:RFAM;Acc:RF00030]0.34542 1.00E-05 ENSOCUG00000007390 LINC00935 Uncharacterized4:33085799-33108975 protein [Source:UniProtKB/TrEMBL;Acc:G1SSY3]0.343366667 1.00E-05 ENSOCUG00000023206 - Uncharacterized18:45140252-45257588 protein [Source:UniProtKB/TrEMBL;Acc:G1TNI2]0.339033333 1.00E-05 ENSOCUG00000016466 ACBD7 acyl-CoA binding16:46575878-46581293 domain containing0.334786333 7 [Source:HGNC Symbol;Acc:HGNC:17715] 1.00E-05 ENSOCUG00000007694 CNIH3 cornichon family16:48626023-48726482 AMPA receptor0.334508667 auxiliary protein 3 [Source:HGNC 1.00E-05 Symbol;Acc:HGNC:26802]

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ENSOCUG00000023445 - Uncharacterized14:157671078-157671546 protein [Source:UniProtKB/TrEMBL;Acc:G1TEW2]0.334210333 1.00E-05 ENSOCUG00000000445 BEX4 brain expressed,X:86817415-86817778 X-linked 4 [Source:HGNC0.326905667 Symbol;Acc:HGNC:25475] 1.00E-05 ENSOCUG00000026771 - GL018747:710893-7112860.324968333 1.00E-05 ENSOCUG00000018217 7SK 7SK RNA [Source:RFAM;Acc:RF00100]12:70829294-710129450.313538 1.00E-05 ENSOCUG00000022088 - 12:44020227-440211480.308245 1.00E-05 ENSOCUG00000025093 FAM57B family with 6:18419510-18423614sequence similarity 57,0.303574 member B [Source:HGNC 1.00E-05 Symbol;Acc:HGNC:25295] ENSOCUG00000023287 - GL018965:75858-762040.301507333 1.00E-05 ENSOCUG00000013068 PYY Peptide YY 19:44337141-44337676Peptide YY(3-36) [Source:UniProtKB/Swiss-Prot;Acc:Q9TR93]0.301044333 1.00E-05 ENSOCUG00000003616 CD70 CD70 moleculeGL019202:51358-54347 [Source:HGNC Symbol;Acc:HGNC:11937]0.29089 1.00E-05 ENSOCUG00000028197 - 9:105804587-1058049710.279619333 1.00E-05 ENSOCUG00000026359 GP9 glycoprotein9:7908173-7909068 IX (platelet) [Source:HGNC0.276541667 Symbol;Acc:HGNC:4444] 1.00E-05 ENSOCUG00000018302 7SK 7SK RNA [Source:RFAM;Acc:RF00100]2:74302563-743957960.273679333 1.00E-05 ENSOCUG00000009617 - UncharacterizedX:88194773-88264088 protein [Source:UniProtKB/TrEMBL;Acc:G1U988]0.271046333 1.00E-05 ENSOCUG00000023927 SPRN Uncharacterized18:69660087-69674827 protein [Source:UniProtKB/TrEMBL;Acc:G1THM0]0.259701667 1.00E-05 ENSOCUG00000029230 - Uncharacterized1:192713791-192726847 protein [Source:UniProtKB/TrEMBL;Acc:U3KPC6]0.25835 1.00E-05 ENSOCUG00000018760 7SK 7SK RNA [Source:RFAM;Acc:RF00100]16:49770352-499030300.253963667 1.00E-05 ENSOCUG00000007035 OSTN osteocrin [Source:HGNC14:86942152-86965459 Symbol;Acc:HGNC:29961]0.253333 1.00E-05 ENSOCUG00000006459 - 3:76011332-760123100.252271333 1.00E-05 ENSOCUG00000021207 - 7:74355211-74355553 0.251125 1.00E-05 ENSOCUG00000019412 7SK 7SK RNA [Source:RFAM;Acc:RF00100]12:128188236-1281885400.248906667 1.00E-05 ENSOCUG00000021188 - 9:624813-626113 0.247715333 1.00E-05 ENSOCUG00000020981 - UncharacterizedAAGW02083341:5391-5685 protein [Source:UniProtKB/TrEMBL;Acc:G1TRH6]0.240628 1.00E-05 ENSOCUG00000025987 BOD1 UncharacterizedDraft8:53938127-53938545 protein [Source:UniProtKB/TrEMBL;Acc:G1THG1]0.240196667 1.00E-05 ENSOCUG00000026648 - GL018740:584505-5848550.239396 1.00E-05 ENSOCUG00000021429 7SK 7SK RNA [Source:RFAM;Acc:RF00100]18:19967341-199676470.238654667 1.00E-05 ENSOCUG00000001424 OTOR otoraplin [Source:HGNC4:19403200-19406226 Symbol;Acc:HGNC:8517]0.238068667 1.00E-05 ENSOCUG00000003864 - GL018820:42820-4659480.233770333 1.00E-05 ENSOCUG00000005554 - UncharacterizedGL019089:102798-104357 protein [Source:UniProtKB/TrEMBL;Acc:G1SP69]0.232532667 1.00E-05 ENSOCUG00000025854 - Uncharacterized2:115112085-115112637 protein [Source:UniProtKB/TrEMBL;Acc:G1TFP0]0.232216667 1.00E-05 ENSOCUG00000021787 - UncharacterizedAAGW02081160:10778-29544 protein [Source:UniProtKB/TrEMBL;Acc:G1TNC4]0.231455 1.00E-05 ENSOCUG00000025893 - Uncharacterized16:22729562-22735840 protein [Source:UniProtKB/TrEMBL;Acc:G1TKR9]0.227709333 1.00E-05 ENSOCUG00000021033 CST9 4:13387518-13390601 0.225797 1.00E-05 ENSOCUG00000024687 - 8:61903615-620968640.224829333 1.00E-05 ENSOCUG00000027525 - GL018700:766130-7672860.223203667 1.00E-05 ENSOCUG00000023794 - 7:9014588-9014905 0.223119 1.00E-05 ENSOCUG00000021688 - UncharacterizedGL018701:8530572-8531154 protein [Source:UniProtKB/TrEMBL;Acc:G1TQ45]0.215167 1.00E-05 ENSOCUG00000027665 - Olfactory receptorGL018699:4762905-4763835 [Source:UniProtKB/TrEMBL;Acc:G1U5X3]0.211631 1.00E-05 ENSOCUG00000023572 - 6:3987906-39883800.211544333 1.00E-05 ENSOCUG00000024198 - UncharacterizedGL018820:708093-708529 protein [Source:UniProtKB/TrEMBL;Acc:G1U1G9]0.205819 1.00E-05 ENSOCUG00000014341 - X:104325704-1043260770.205744 1.00E-05 ENSOCUG00000027030 - X:60118578-601189050.201784333 1.00E-05 ENSOCUG00000009984 DEFB124 defensin, beta4:7711274-7716649 124 [Source:HGNC Symbol;Acc:HGNC:18104]0.198846 1.00E-05 ENSOCUG00000020916 - 18:21696355-216970260.196783333 1.00E-05 ENSOCUG00000018884 7SK 7SK RNA [Source:RFAM;Acc:RF00100]11:60496288-604966100.195930667 1.00E-05 ENSOCUG00000025917 - Uncharacterized17:42149218-42240905 protein [Source:UniProtKB/TrEMBL;Acc:G1TJE4]0.194317333 1.00E-05 ENSOCUG00000011637 GUCA2B guanylate cyclase13:124526807-124529660 activator 2B (uroguanylin)0.186854333 [Source:HGNC 1.00E-05 Symbol;Acc:HGNC:4683] ENSOCUG00000013045 UBE2E2 ubiquitin-conjugating12:73480120-73480699 enzyme E2E 0.1855752 [Source:HGNC Symbol;Acc:HGNC:12478] 1.00E-05 ENSOCUG00000001516 - 15:4434502-44348810.183133667 1.00E-05 ENSOCUG00000022269 CRYBB1 crystallin, betaGL018723:207347-222038 B1 [Source:HGNC0.181181667 Symbol;Acc:HGNC:2397] 1.00E-05 ENSOCUG00000020396 7SK 7SK RNA [Source:RFAM;Acc:RF00100]GL018719:295209-2955490.180869 1.00E-05

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ENSOCUG00000003834 - Uncharacterized2:98664529-98889753 protein [Source:UniProtKB/TrEMBL;Acc:G1SKI3]0.180483667 1.00E-05 ENSOCUG00000021237 - UncharacterizedGL018699:9815745-9816063 protein [Source:UniProtKB/TrEMBL;Acc:G1TUQ7]0.176967 1.00E-05 ENSOCUG00000021407 - Uncharacterized5:27698046-27716185 protein [Source:UniProtKB/TrEMBL;Acc:G1TXR9]0.176947 1.00E-05 ENSOCUG00000024651 - 7:142050947-1420517490.173806667 1.00E-05 ENSOCUG00000021548 - Uncharacterized15:75065544-75066066 protein [Source:UniProtKB/TrEMBL;Acc:G1U582]0.171412 1.00E-05 ENSOCUG00000027110 PPP4R1L 15:24063744-241356320.167887333 1.00E-05 ENSOCUG00000025495 - Uncharacterized8:28427706-28437353 protein [Source:UniProtKB/TrEMBL;Acc:G1U480]0.166364 1.00E-05 ENSOCUG00000000522 - Uncharacterized6:7695322-7708933 protein [Source:UniProtKB/TrEMBL;Acc:G1SDH1]0.166103 1.00E-05 ENSOCUG00000027272 GPR3 G protein-coupled13:138046455-138047448 receptor 3 [Source:HGNC0.165367333 Symbol;Acc:HGNC:4484] 1.00E-05 ENSOCUG00000015761 ANKRD33 ankyrin repeat4:36060310-36062252 domain 33 [Source:HGNC0.163336667 Symbol;Acc:HGNC:13788] 1.00E-05 ENSOCUG00000022425 POU4F3 POU class 43:28339563-28340076 homeobox 3 [Source:HGNC0.154787667 Symbol;Acc:HGNC:9220] 1.00E-05 ENSOCUG00000023416 - 14:73801690-738026090.152563 1.00E-05 ENSOCUG00000026722 - 13:12842623-128430520.150995667 1.00E-05 ENSOCUG00000029689 - UncharacterizedGL019186:31099-221396 protein [Source:UniProtKB/TrEMBL;Acc:G1SJM4]0.150940333 1.00E-05 ENSOCUG00000026587 - UncharacterizedGL019438:78217-78833 protein [Source:UniProtKB/TrEMBL;Acc:G1TPA3]0.150013333 1.00E-05 ENSOCUG00000027428 - Uncharacterized1:70723062-70723515 protein [Source:UniProtKB/TrEMBL;Acc:G1TP45]0.14521 1.00E-05 ENSOCUG00000024291 PWP2 Uncharacterized4:12787657-12788053 protein [Source:UniProtKB/TrEMBL;Acc:G1TIM5]0.144022333 1.00E-05 ENSOCUG00000025240 - Uncharacterized4:48453273-48453711 protein [Source:UniProtKB/TrEMBL;Acc:G1TTC6]0.143796 1.00E-05 ENSOCUG00000028138 - Uncharacterized6:18207334-18209090 protein [Source:UniProtKB/TrEMBL;Acc:G1TG02]0.142845333 1.00E-05 ENSOCUG00000003433 GMCSF Oryctolagus3:15143062-15146030 cuniculus granulate-macrophage0.142529333 stimulating factor 1.00E-05 (GMCSF), mRNA. [Source:RefSeq mRNA;Acc:NM_001171257] ENSOCUG00000006744 CES5A carboxylesterase5:12161088-12528699 5A [Source:HGNC0.141122667 Symbol;Acc:HGNC:26459] 1.00E-05 ENSOCUG00000022645 HPCAL4 hippocalcin 13:126826071-126828854like 4 [Source:HGNC0.140776333 Symbol;Acc:HGNC:18212] 1.00E-05 ENSOCUG00000001614 - UncharacterizedDraft13:34264291-34265212 protein [Source:UniProtKB/TrEMBL;Acc:G1SFS2]0.140509333 1.00E-05 ENSOCUG00000026641 - GL018760:136158-1367710.139880667 1.00E-05 ENSOCUG00000015677 PLAC8L1 PLAC8-like3:28041489-28152938 1 [Source:HGNC Symbol;Acc:HGNC:31746]0.139536 1.00E-05 ENSOCUG00000022739 - X:9670319-96707850.139495333 1.00E-05 ENSOCUG00000004512 - GL019369:20-375670.139080333 1.00E-05 ENSOCUG00000026808 - GL018795:327067-4275770.137973 1.00E-05 ENSOCUG00000024891 KBTBD11 kelch repeatGL018865:488358-637412 and BTB (POZ) domain0.137892333 containing 11 [Source:HGNC 1.00E-05 Symbol;Acc:HGNC:29104] ENSOCUG00000023135 - UncharacterizedX:75833969-75834413 protein [Source:UniProtKB/TrEMBL;Acc:G1TZ44]0.135572 1.00E-05 ENSOCUG00000024445 - Uncharacterized9:90025789-90400731 protein [Source:UniProtKB/TrEMBL;Acc:G1TMI7]0.134421 1.00E-05 ENSOCUG00000026814 - Uncharacterized3:66798494-66799423 protein [Source:UniProtKB/TrEMBL;Acc:G1TY59]0.133977333 1.00E-05 ENSOCUG00000023936 - X:78646835-786472790.132966 1.00E-05 ENSOCUG00000026819 RXFP4 relaxin/insulin-like13:36901960-36903079 family peptide receptor0.132775 4 [Source:HGNC 1.00E-05 Symbol;Acc:HGNC:14666] ENSOCUG00000026302 - GL018749:970182-10402330.128273333 1.00E-05 ENSOCUG00000007106 - Ribonuclease17:41368772-41369243 A E1; Uncharacterized0.128180333 protein [Source:UniProtKB/TrEMBL;Acc:G1TY93] 1.00E-05 ENSOCUG00000025812 - Uncharacterized7:98073558-98132613 protein [Source:UniProtKB/TrEMBL;Acc:G1TJT7]0.127575333 1.00E-05 ENSOCUG00000001019 DMRTA2 DMRT-like 13:116251615-116255250family A2 [Source:HGNC0.1273699 Symbol;Acc:HGNC:13908] 1.00E-05 ENSOCUG00000024306 - Uncharacterized5:29085409-29085880 protein [Source:UniProtKB/TrEMBL;Acc:G1TYW9]0.125679 1.00E-05 ENSOCUG00000020945 - Uncharacterized4:63510919-63511360 protein [Source:UniProtKB/TrEMBL;Acc:G1TIP6]0.125464667 1.00E-05 ENSOCUG00000002237 - UncharacterizedGL018827:790922-791426 protein [Source:UniProtKB/TrEMBL;Acc:G1SH37]0.124793333 1.00E-05 ENSOCUG00000023080 - Olfactory receptor17:39785037-39785973 [Source:UniProtKB/TrEMBL;Acc:G1TM06]0.122935667 1.00E-05 ENSOCUG00000015954 - 8:69358558-693591180.122413333 1.00E-05 ENSOCUG00000021138 - 2:99592778-997630410.121513333 1.00E-05 ENSOCUG00000001411 GALR3 galanin receptorGL018972:110129-111971 3 [Source:HGNC Symbol;Acc:HGNC:4134]0.121116 1.00E-05 ENSOCUG00000008168 - Uncharacterized18:64068221-64093410 protein [Source:UniProtKB/TrEMBL;Acc:G1SUL9]0.121059333 1.00E-05 ENSOCUG00000023296 - UncharacterizedGL018738:95145-96452 protein [Source:UniProtKB/TrEMBL;Acc:G1TYF1]0.120296567 1.00E-05 ENSOCUG00000015565 KCNJ5 potassium inwardly-rectifying1:87949181-87982684 channel,0.1199365 subfamily J, member 1.00E-05 5 [Source:HGNC Symbol;Acc:HGNC:6266] ENSOCUG00000016681 - Olfactory receptor1:191220973-191221912 [Source:UniProtKB/TrEMBL;Acc:G1U7Z2]0.119526667 1.00E-05 ENSOCUG00000005612 - 12:139249124-1392496710.119131667 1.00E-05

https://mc06.manuscriptcentral.com/genome-pubs Genome Page 60 of 138

ENSOCUG00000016749 - Uncharacterized15:5991702-5992322 protein [Source:UniProtKB/TrEMBL;Acc:G1TC98]0.118961667 1.00E-05 ENSOCUG00000027629 - UncharacterizedGL019806:8639-9650 protein [Source:UniProtKB/TrEMBL;Acc:G1U530]0.118822667 1.00E-05 ENSOCUG00000028220 MIOX myo-inositolGL019140:187507-188834 oxygenase [Source:HGNC0.118270667 Symbol;Acc:HGNC:14522] 1.00E-05 ENSOCUG00000007942 LY6G5C lymphocyte 12:20488716-20496806antigen 6 complex,0.117877333 locus G5C [Source:HGNC 1.00E-05 Symbol;Acc:HGNC:13932] ENSOCUG00000027248 PCP2 Purkinje cellGL018767:827778-829244 protein 2 [Source:HGNC0.11698 Symbol;Acc:HGNC:30209] 1.00E-05 ENSOCUG00000002990 - UncharacterizedX:33056570-33061324 protein [Source:UniProtKB/TrEMBL;Acc:G1SIS9]0.116579767 1.00E-05 ENSOCUG00000008028 NAP1L5 nucleosome15:61346587-61488514 assembly protein 1-like 0.113515 [Source:HGNC Symbol;Acc:HGNC:19968] 1.00E-05 ENSOCUG00000027298 - Uncharacterized17:42149218-42240905 protein [Source:UniProtKB/TrEMBL;Acc:G1TM94]0.111679333 1.00E-05 ENSOCUG00000023690 - UncharacterizedX:31457740-31459999 protein [Source:UniProtKB/TrEMBL;Acc:G1TR41]0.111637333 1.00E-05 ENSOCUG00000009701 CSF3 colony stimulating19:41228717-41230859 factor 3 (granulocyte)0.110520333 [Source:HGNC Symbol;Acc:HGNC:2438] 1.00E-05 ENSOCUG00000002718 - UncharacterizedGL018705:4354206-4354884 protein [Source:UniProtKB/TrEMBL;Acc:G1SPH4]0.109981 1.00E-05 ENSOCUG00000022127 KBTBD13 kelch repeat17:7221576-7222946 and BTB (POZ) domain0.108658 containing 13 [Source:HGNC 1.00E-05 Symbol;Acc:HGNC:37227] ENSOCUG00000027821 - GL018777:1114417-11148190.108581667 1.00E-05 ENSOCUG00000027221 - 7:21978279-224401320.107503333 1.00E-05 ENSOCUG00000010970 - 7:103202327-1032028060.106957667 1.00E-05 ENSOCUG00000013269 - 5:19777535-197780110.106774667 1.00E-05 ENSOCUG00000023292 - U1 small nuclear2:163828048-163828528 ribonucleoprotein0.106180667 C [Source:UniProtKB/TrEMBL;Acc:G1TTQ6] 1.00E-05 ENSOCUG00000013027 - Olfactory receptorGL018747:722529-723468 [Source:UniProtKB/TrEMBL;Acc:G1TVE0]0.106005 1.00E-05 ENSOCUG00000021583 - Uncharacterized13:124348152-124504886 protein [Source:UniProtKB/TrEMBL;Acc:G1U3Y2]0.103748 1.00E-05 ENSOCUG00000020929 - GL019079:188037-1884410.103568 1.00E-05 ENSOCUG00000013186 TNFRSF13Ctumor necrosisGL018734:643375-644585 factor receptor superfamily,0.102137333 member 13C [Source:HGNC 1.00E-05 Symbol;Acc:HGNC:17755] ENSOCUG00000023967 - UncharacterizedAAGW02082138:5772-7406 protein [Source:UniProtKB/TrEMBL;Acc:G1TQ15]0.101307333 1.00E-05 ENSOCUG00000024276 - DraftX:52289618-522900420.101098333 1.00E-05 ENSOCUG00000008477 - UncharacterizedGL019577:33-2270 protein [Source:UniProtKB/TrEMBL;Acc:G1SV94]0.099908333 1.00E-05 ENSOCUG00000024246 - 17:48653141-486540210.099538 1.00E-05 ENSOCUG00000011472 FOXJ1 forkhead boxGL018843:539110-541883 J1 [Source:HGNC Symbol;Acc:HGNC:3816]0.0993415 1.00E-05 ENSOCUG00000022551 ARTN artemin [Source:HGNC13:122752410-122753479 Symbol;Acc:HGNC:727]0.099268333 1.00E-05 ENSOCUG00000027104 TAS2R41 taste receptor,7:8624967-8625891 type 2, member 41 [Source:HGNC0.098643 Symbol;Acc:HGNC:18883] 1.00E-05 ENSOCUG00000023668 - OryctolagusGL018713:117449-120505 cuniculus corticostatin-60.098099333 (LOC100009136), mRNA. 1.00E-05 [Source:RefSeq mRNA;Acc:NM_001082300] ENSOCUG00000025899 - 17:12394486-123949620.096530333 1.00E-05 ENSOCUG00000015251 - 19:43324861-433497280.096003333 1.00E-05 ENSOCUG00000000602 - AAGW02081496:2245-34040.095660667 1.00E-05 ENSOCUG00000023240 - Uncharacterized7:141855657-141856678 protein [Source:UniProtKB/TrEMBL;Acc:G1TYT8]0.095647 1.00E-05 ENSOCUG00000016070 - Uncharacterized1:125149225-125150512 protein [Source:UniProtKB/TrEMBL;Acc:G1TAU3]0.095362333 1.00E-05 ENSOCUG00000013112 PSMB11 proteasome 17:43267131-43268043(prosome, macropain)0.093568333 subunit, beta type, 11 [Source:HGNC 1.00E-05 Symbol;Acc:HGNC:31963] ENSOCUG00000022591 SSB Single-strandedX:98660003-98660450 DNA-binding protein0.092624 [Source:UniProtKB/TrEMBL;Acc:G1TWH4] 1.00E-05 ENSOCUG00000025488 - OryctolagusGL018713:97163-99684 cuniculus defensin0.092408667 NP-4 (LOC100009135), mRNA. 1.00E-05 [Source:RefSeq mRNA;Acc:NM_001082299] ENSOCUG00000001600 - Uncharacterized14:81187413-81188648 protein [Source:UniProtKB/TrEMBL;Acc:G1TI62]0.092333333 1.00E-05 ENSOCUG00000024592 - Uncharacterized17:43997175-44004728 protein [Source:UniProtKB/TrEMBL;Acc:G1TX79]0.092235667 1.00E-05 ENSOCUG00000016484 AIFM3 apoptosis-inducing21:4923929-4932841 factor, mitochondrion-associated,0.092064267 3 [Source:HGNC 1.00E-05 Symbol;Acc:HGNC:26398] ENSOCUG00000026171 TMEM253 transmembrane17:41411348-41413166 protein 253 [Source:HGNC0.09182 Symbol;Acc:HGNC:32545] 1.00E-05 ENSOCUG00000024837 - 12:33652270-336547940.091509 1.00E-05 ENSOCUG00000016030 HMGB3 high mobility1:163247969-163249725 group box 3 [Source:HGNC0.091479 Symbol;Acc:HGNC:5004] 1.00E-05 ENSOCUG00000026947 - UncharacterizedGL018717:3798792-3806528 protein [Source:UniProtKB/TrEMBL;Acc:G1T1U4]0.0913553 1.00E-05 ENSOCUG00000016064 C17orf105 chromosome19:44212883-44216002 17 open reading frame0.090445667 105 [Source:HGNC Symbol;Acc:HGNC:37241] 1.00E-05 ENSOCUG00000025270 - Uncharacterized2:56001261-56001759 protein [Source:UniProtKB/TrEMBL;Acc:G1TF87]0.090425 1.00E-05 ENSOCUG00000014523 SPATA17 spermatogenesis16:55316578-55628027 associated 17 [Source:HGNC0.089939967 Symbol;Acc:HGNC:25184] 1.00E-05 ENSOCUG00000015568 C8orf74 chromosome2:39301200-39324145 8 open reading frame 0.08970974 [Source:HGNC Symbol;Acc:HGNC:32296] 1.00E-05 ENSOCUG00000014410 - UncharacterizedGL018705:5680100-5786595 protein [Source:UniProtKB/TrEMBL;Acc:G1T7C3]0.089506 1.00E-05 ENSOCUG00000007213 HMGB4 high mobilityGL018704:4179057-4793829 group box 4 [Source:HGNC0.089044667 Symbol;Acc:HGNC:24954] 1.00E-05

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ENSOCUG00000016373 - Uncharacterized12:126752443-126753402 protein [Source:UniProtKB/TrEMBL;Acc:G1TYV1]0.088244667 1.00E-05 ENSOCUG00000006726 - UncharacterizedAAGW02082138:12269-14780 protein [Source:UniProtKB/TrEMBL;Acc:G1SRK4]0.086255667 1.00E-05 ENSOCUG00000015175 RESP18 regulated endocrine-specific7:160553883-160560430 protein0.085560667 18 [Source:HGNC Symbol;Acc:HGNC:33762] 1.00E-05 ENSOCUG00000003909 GLIPR1L1 GLI pathogenesis-related4:54152691-54174173 1 like 1 [Source:HGNC0.085548 Symbol;Acc:HGNC:28392] 1.00E-05 ENSOCUG00000022173 - UncharacterizedGL019699:28174-29135 protein [Source:UniProtKB/TrEMBL;Acc:G1TF83]0.085195 1.00E-05 ENSOCUG00000023154 - UncharacterizedX:48680464-48680929 protein [Source:UniProtKB/TrEMBL;Acc:G1TJF3]0.083640667 1.00E-05 ENSOCUG00000017530 SLC10A5 solute carrier3:97336811-97338128 family 10, member0.083272667 5 [Source:HGNC Symbol;Acc:HGNC:22981] 1.00E-05 ENSOCUG00000000239 ATP6V1G3 ATPase, H+16:72677082-72696733 transporting, lysosomal0.081506667 13kDa, V1 subunit G3 1.00E-05 [Source:HGNC Symbol;Acc:HGNC:18265] ENSOCUG00000011640 - Uncharacterized14:30749333-30749867 protein [Source:UniProtKB/TrEMBL;Acc:G1TQA2]0.081419 1.00E-05 ENSOCUG00000026071 PIP5KL1 phosphatidylinositol-4-phosphateGL018847:478107-693595 5-kinase-like0.081087 1 [Source:HGNC 1.00E-05 Symbol;Acc:HGNC:28711] ENSOCUG00000007301 - UncharacterizedGL018781:840720-890390 protein [Source:UniProtKB/TrEMBL;Acc:G1SSR9]0.081061333 1.00E-05 ENSOCUG00000026837 CACNG2 calcium channel,4:85248430-85257667 voltage-dependent,0.080213667 gamma subunit 2 [Source:HGNC 1.00E-05 Symbol;Acc:HGNC:1406] ENSOCUG00000000506 - Uncharacterized3:143914037-143915274 protein [Source:UniProtKB/TrEMBL;Acc:G1SDF8]0.079377333 1.00E-05 ENSOCUG00000010645 - 40S ribosomal13:20267395-20268148 protein S6 [Source:UniProtKB/TrEMBL;Acc:G1TK73]0.078774667 1.00E-05 ENSOCUG00000026905 - 13:95315190-953156570.078353 1.00E-05 ENSOCUG00000010266 MYO3B Uncharacterized7:110072308-110105253 protein [Source:UniProtKB/TrEMBL;Acc:G1TH21]0.0778732 1.00E-05 ENSOCUG00000012140 - UncharacterizedGL018700:3338177-3339610 protein [Source:UniProtKB/TrEMBL;Acc:G1T2P1]0.077371333 1.00E-05 ENSOCUG00000027590 - 1:50759964-507604390.076540667 1.00E-05 ENSOCUG00000024857 - GL018724:2539428-26721370.076399 1.00E-05 ENSOCUG00000025182 - Olfactory receptor1:192554161-192555100 [Source:UniProtKB/TrEMBL;Acc:G1TUY9]0.075961333 1.00E-05 ENSOCUG00000015848 - UncharacterizedX:23045005-23045557 protein [Source:UniProtKB/TrEMBL;Acc:G1TAC2]0.075726667 1.00E-05 ENSOCUG00000015346 - 13:125980855-1259813820.075511333 1.00E-05 ENSOCUG00000005183 CLPSL1 colipase-likeDraft12:25812822-25815945 1 [Source:HGNC 0.075027333Symbol;Acc:HGNC:21251] 1.00E-05 ENSOCUG00000024591 - 15:41292086-412925560.074805667 1.00E-05 ENSOCUG00000000869 - UncharacterizedAAGW02081485:16929-17741 protein [Source:UniProtKB/TrEMBL;Acc:G1U7B6]0.074565667 1.00E-05 ENSOCUG00000023868 - 12:97772063-977726160.073892667 1.00E-05 ENSOCUG00000000178 CYP26A1 cytochrome 18:40838323-40842192P450, family 26, subfamily0.073497333 A, polypeptide 1 [Source:HGNC 1.00E-05 Symbol;Acc:HGNC:2603] ENSOCUG00000024030 - GL018817:266391-2670290.072602 1.00E-05 ENSOCUG00000015369 TLX2 T-cell leukemia2:112025689-112027048 homeobox 2 [Source:HGNC0.0725 Symbol;Acc:HGNC:5057] 1.00E-05 ENSOCUG00000023676 - UncharacterizedAAGW02080735:25888-36474 protein [Source:UniProtKB/TrEMBL;Acc:G1TMU7]0.072074 1.00E-05 ENSOCUG00000013907 FAM83E family with GL019039:60626-189176sequence similarity0.072058633 83, member E [Source:HGNC 1.00E-05 Symbol;Acc:HGNC:25972] ENSOCUG00000011071 - Uncharacterized8:29079217-29083704 protein [Source:UniProtKB/TrEMBL;Acc:G1T0J5]0.071862733 1.00E-05 ENSOCUG00000027097 - Uncharacterized8:16787929-16788799 protein [Source:UniProtKB/TrEMBL;Acc:G1U554]0.071743933 1.00E-05 ENSOCUG00000027926 OR2V1 olfactory receptor,11:31859699-31860647 family 2, subfamily0.071026667 V, member 1 [Source:HGNC 1.00E-05 Symbol;Acc:HGNC:8280] ENSOCUG00000026544 LCN9 Uncharacterized1:367323-372684 protein [Source:UniProtKB/TrEMBL;Acc:G1U400]0.0710138 1.00E-05 ENSOCUG00000012984 - AAGW02081401:703-16430.070849333 1.00E-05 ENSOCUG00000021193 OR52B2 olfactory receptor,1:147174646-147175600 family 52, subfamily0.070789 B, member 2 [Source:HGNC 1.00E-05 Symbol;Acc:HGNC:15207] ENSOCUG00000016008 FANCD2OSFANCD2 oppositeGL018802:157956-158493 strand [Source:HGNC0.070225333 Symbol;Acc:HGNC:28623] 1.00E-05 ENSOCUG00000005850 GABRR3 gamma-aminobutyric14:122532803-122593006 acid (GABA)0.069952667 A receptor, rho 3 (gene/pseudogene) 1.00E-05 [Source:HGNC Symbol;Acc:HGNC:17969] ENSOCUG00000017811 - Uncharacterized1:105325532-105326360 protein [Source:UniProtKB/TrEMBL;Acc:G1TNW7]0.069374667 1.00E-05 ENSOCUG00000006178 OR56A3 olfactory receptor,1:146981234-146982182 family 56, subfamily0.069171 A, member 3 [Source:HGNC 1.00E-05 Symbol;Acc:HGNC:14786] ENSOCUG00000014968 DDC dopa decarboxylaseGL018745:1893311-1936239 (aromatic L-amino0.069046 acid decarboxylase) 1.00E-05 [Source:HGNC Symbol;Acc:HGNC:2719] ENSOCUG00000026282 - Uncharacterized1:192163297-192165024 protein [Source:UniProtKB/TrEMBL;Acc:G1TJD0]0.069024667 1.00E-05 ENSOCUG00000021294 TMEM95 transmembrane19:11797530-11798827 protein 95 [Source:HGNC0.068847333 Symbol;Acc:HGNC:27898] 1.00E-05 ENSOCUG00000026520 C5orf49 chromosomeGL018756:1394507-1408195 5 open reading frame 0.06880549 [Source:HGNC Symbol;Acc:HGNC:27028] 1.00E-05 ENSOCUG00000007698 C1orf111 chromosome13:30631331-30975986 1 open reading frame0.068784667 111 [Source:HGNC Symbol;Acc:HGNC:27648] 1.00E-05 ENSOCUG00000024095 - 9:15750688-159394490.068531333 1.00E-05 ENSOCUG00000007395 - Olfactory receptorGL019045:92703-93621 [Source:UniProtKB/TrEMBL;Acc:G1TFQ2]0.067653 1.00E-05 ENSOCUG00000027144 - Olfactory receptor1:191116918-191117860 [Source:UniProtKB/TrEMBL;Acc:G1U260]0.067587667 1.00E-05 ENSOCUG00000022893 KLF14 Kruppel-like7:9249868-9391435 factor 14 [Source:HGNC0.067183 Symbol;Acc:HGNC:23025] 1.00E-05

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ENSOCUG00000027287 - Uncharacterized11:2561772-2563880 protein [Source:UniProtKB/TrEMBL;Acc:G1TSC1]0.066855667 1.00E-05 ENSOCUG00000027826 - Olfactory receptorAAGW02081401:15194-16130 [Source:UniProtKB/TrEMBL;Acc:G1U193]0.066653 1.00E-05 ENSOCUG00000016947 CCDC153 coiled-coil domainGL018823:652866-657878 containing 1530.066394667 [Source:HGNC Symbol;Acc:HGNC:27446] 1.00E-05 ENSOCUG00000001597 ADAMDEC1ADAM-like,2:45334386-45352776 decysin 1 [Source:HGNC0.066166533 Symbol;Acc:HGNC:16299] 1.00E-05 ENSOCUG00000028222 - Olfactory receptor1:92709397-92710327 [Source:UniProtKB/TrEMBL;Acc:G1U4J1]0.066059333 1.00E-05 ENSOCUG00000025360 - 1:151567967-1520815770.064984667 1.00E-05 ENSOCUG00000026374 - UncharacterizedGL018981:8699-10728 protein [Source:UniProtKB/TrEMBL;Acc:G1TRT4]0.06479 1.00E-05 ENSOCUG00000016383 - 1:8374787-83757040.064683667 1.00E-05 ENSOCUG00000016150 - X:68816852-688182290.064598 1.00E-05 ENSOCUG00000025144 - Olfactory receptor1:148189076-148190000 [Source:UniProtKB/TrEMBL;Acc:G1TPI9]0.063858667 1.00E-05 ENSOCUG00000029162 - Uncharacterized17:61270425-61271426 protein [Source:UniProtKB/TrEMBL;Acc:U3KPF3]0.063382667 1.00E-05 ENSOCUG00000026446 - Uncharacterized2:98664529-98889753 protein [Source:UniProtKB/TrEMBL;Acc:G1TWK9]0.063311333 1.00E-05 ENSOCUG00000026780 - Olfactory receptor17:42958057-42958987 [Source:UniProtKB/TrEMBL;Acc:G1TL39]0.061427667 1.00E-05 ENSOCUG00000025891 SF3A2 splicing factor1:47080155-47400649 3a, subunit 2, 66kDa0.061314867 [Source:HGNC Symbol;Acc:HGNC:10766] 1.00E-05 ENSOCUG00000028016 - Uncharacterized7:35707002-35708503 protein [Source:UniProtKB/TrEMBL;Acc:G1U8P8]0.061298667 1.00E-05 ENSOCUG00000024164 ADIPOR1 adiponectin 12:21750614-21751775receptor 1 [Source:HGNC0.061126667 Symbol;Acc:HGNC:24040] 1.00E-05 ENSOCUG00000007693 - GL018707:2057631-20586260.0606387 1.00E-05 ENSOCUG00000021525 ONECUT2 one cut homeobox9:97985177-98026193 2 [Source:HGNC0.060527667 Symbol;Acc:HGNC:8139] 1.00E-05 ENSOCUG00000024831 - 4:58106279-581070400.060468333 1.00E-05 ENSOCUG00000009516 CHRNA6 cholinergic receptor,GL018706:627990-640671 nicotinic, alpha0.059754867 6 (neuronal) [Source:HGNC 1.00E-05 Symbol;Acc:HGNC:15963] ENSOCUG00000021047 - GL018702:5000290-50010440.058430333 1.00E-05 ENSOCUG00000026738 - Olfactory receptor13:34338139-34339087 [Source:UniProtKB/TrEMBL;Acc:G1U6C1]0.057363333 1.00E-05 ENSOCUG00000009087 RBPJL recombinationDraftGL018725:458452-465665 signal binding protein0.057167667 for immunoglobulin 1.00E-05kappa J region-like [Source:HGNC Symbol;Acc:HGNC:13761] ENSOCUG00000021906 - slowmo homolog12:43597466-43598047 2 (Drosophila)0.056444667 [Source:HGNC Symbol;Acc:HGNC:15892] 1.00E-05 ENSOCUG00000026637 - 18:4312589-43131400.056047333 1.00E-05 ENSOCUG00000023930 LYZL6 lysozyme-like19:45672181-45675945 6 [Source:HGNC0.055796333 Symbol;Acc:HGNC:29614] 1.00E-05 ENSOCUG00000022204 - UncharacterizedGL019073:34207-34842 protein [Source:UniProtKB/TrEMBL;Acc:G1TQJ2]0.055531 1.00E-05 ENSOCUG00000005906 - 15:21946257-219468780.055300667 1.00E-05 ENSOCUG00000021771 LCTL lactase-like 17:5840483-5848646[Source:HGNC Symbol;Acc:HGNC:15583]0.055273867 1.00E-05 ENSOCUG00000022822 GBX1 gastrulation 13:12561233-12578383brain homeobox 1 [Source:HGNC0.0550904 Symbol;Acc:HGNC:4185] 1.00E-05 ENSOCUG00000008058 - 14:92322671-923247220.054127667 1.00E-05 ENSOCUG00000023656 - 7:63936116-639367850.053828333 1.00E-05 ENSOCUG00000002529 GRXCR1 glutaredoxin,2:31984629-32120495 cysteine rich 1 [Source:HGNC0.053126667 Symbol;Acc:HGNC:31673] 1.00E-05 ENSOCUG00000005891 ELAVL2 ELAV like neuron-specific1:29874219-29959497 RNA0.053082833 binding protein 2 [Source:HGNC 1.00E-05 Symbol;Acc:HGNC:3313] ENSOCUG00000024731 - GL018879:284533-2851150.053039333 1.00E-05 ENSOCUG00000021043 - UncharacterizedGL018813:101766-104991 protein [Source:UniProtKB/TrEMBL;Acc:G1TWW6]0.052695 1.00E-05 ENSOCUG00000022841 - 3:140059985-1400605700.052315333 1.00E-05 ENSOCUG00000021049 AHNAK2 AHNAK nucleoproteinAAGW02081907:2256-15717 2 [Source:HGNC0.090281026 Symbol;Acc:HGNC:20125] 1.73E-05 ENSOCUG00000006006 SLC28A1 solute carrierGL018738:461797-500025 family 28 (concentrative0.051589 nucleoside transporter), 1.00E-05 member 1 [Source:HGNC Symbol;Acc:HGNC:11001] ENSOCUG00000024470 OR56A1 olfactory receptor,1:147100718-147101666 family 56, subfamily0.051496667 A, member 1 [Source:HGNC 1.00E-05 Symbol;Acc:HGNC:14781] ENSOCUG00000023040 ORYCUNV1R1581UncharacterizedGL018763:633923-634820 protein [Source:UniProtKB/TrEMBL;Acc:G1U912]0.051345667 1.00E-05 ENSOCUG00000006242 - 4:2156729-2157478 0.051301 1.00E-05 ENSOCUG00000006233 - 3:16796056-167967390.050934333 1.00E-05 ENSOCUG00000021790 - Uncharacterized10:8174946-8240702 protein [Source:UniProtKB/TrEMBL;Acc:G1U8M7]0.050870333 1.00E-05 ENSOCUG00000002123 GRM8 glutamate receptor,7:17070435-17990263 metabotropic0.050724667 8 [Source:HGNC Symbol;Acc:HGNC:4600] 1.00E-05 ENSOCUG00000021622 - UncharacterizedGL018890:413-7054 protein [Source:UniProtKB/TrEMBL;Acc:G1TVR0]0.050251333 1.00E-05 ENSOCUG00000003349 IDO2 indoleamineGL018706:2893555-2957788 2,3-dioxygenase 2 0.050232733[Source:HGNC Symbol;Acc:HGNC:27269] 1.00E-05 ENSOCUG00000007072 - Olfactory receptorGL018890:401948-402857 [Source:UniProtKB/TrEMBL;Acc:G1TNL1]0.050191333 1.00E-05 ENSOCUG00000021113 FTH1 Ferritin [Source:UniProtKB/TrEMBL;Acc:G1TRI3]13:118381236-1183819990.049962333 1.00E-05 ENSOCUG00000014961 - Uncharacterized14:95121406-95135717 protein [Source:UniProtKB/TrEMBL;Acc:G1T8F4]0.0499251 1.00E-05

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ENSOCUG00000024594 - Uncharacterized1:92994068-93019083 protein [Source:UniProtKB/TrEMBL;Acc:G1TMK0]0.049271567 1.00E-05 ENSOCUG00000023306 TAC4 Oryctolagus19:37783650-37793713 cuniculus tachykinin0.049002333 4 (hemokinin) (TAC4), mRNA. 1.00E-05 [Source:RefSeq mRNA;Acc:NM_001082165] ENSOCUG00000024881 DIRAS3 DIRAS family,13:98216536-98217226 GTP-binding RAS-like0.048692333 3 [Source:HGNC Symbol;Acc:HGNC:687] 1.00E-05 ENSOCUG00000026031 GLTPD2 glycolipid transfer19:12317990-12319498 protein domain0.047810667 containing 2 [Source:HGNC 1.00E-05 Symbol;Acc:HGNC:33756] ENSOCUG00000027437 - Uncharacterized5:30281669-30369243 protein [Source:UniProtKB/TrEMBL;Acc:G1TQH6]0.047802533 1.00E-05 ENSOCUG00000027920 CA7 carbonic anhydrase5:22255029-22263603 VII [Source:HGNC0.047767967 Symbol;Acc:HGNC:1381] 1.00E-05 ENSOCUG00000028168 - 12:73859206-738601350.047706 1.00E-05 ENSOCUG00000028017 - 18:39146916-391476220.047642667 1.00E-05 ENSOCUG00000006064 - Uncharacterized14:71682594-71683543 protein [Source:UniProtKB/TrEMBL;Acc:G1U365]0.047555333 1.00E-05 ENSOCUG00000013365 - Uncharacterized1:93416755-93417697 protein [Source:UniProtKB/TrEMBL;Acc:G1TP33]0.047356333 1.00E-05 ENSOCUG00000021460 - UncharacterizedGL018841:409973-410906 protein [Source:UniProtKB/TrEMBL;Acc:G1TUV4]0.046142333 1.00E-05 ENSOCUG00000025120 SLC18A3 solute carrier18:5728754-5730353 family 18 (vesicular0.046003333 acetylcholine transporter), 1.00E-05 member 3 [Source:HGNC Symbol;Acc:HGNC:10936] ENSOCUG00000007630 CACNG7 OryctolagusGL018924:119015-136303 cuniculus calcium channel,0.045603 voltage-dependent, 1.00E-05 gamma subunit 7 (CACNG7), mRNA. [Source:RefSeq mRNA;Acc:NM_001171389] ENSOCUG00000014732 RIMKLA ribosomal modification13:124261081-124290797 protein 0.045518333rimK-like family member A 1.00E-05 [Source:HGNC Symbol;Acc:HGNC:28725] ENSOCUG00000022903 - Olfactory receptor17:39966845-39967757 [Source:UniProtKB/TrEMBL;Acc:G1TT69]0.044913333 1.00E-05 ENSOCUG00000003708 C4orf22 chromosome15:69304828-69410535 4 open reading frame0.044872667 22 [Source:HGNC Symbol;Acc:HGNC:28554] 1.00E-05 ENSOCUG00000017073 ARR3 arrestin 3, retinalX:48829553-48842041 (X-arrestin) [Source:HGNC0.044799533 Symbol;Acc:HGNC:710] 1.00E-05 ENSOCUG00000008039 - Olfactory receptor13:34275723-34276659 [Source:UniProtKB/TrEMBL;Acc:G1SUC0]0.044544667 1.00E-05 ENSOCUG00000024721 - Uncharacterized15:98654461-98795608 protein [Source:UniProtKB/TrEMBL;Acc:G1TQM2]0.044473333 1.00E-05 ENSOCUG00000021232 NTSR2 neurotensin 2:160505448-160512282receptor 2 [Source:HGNC0.044256333 Symbol;Acc:HGNC:8040] 1.00E-05 ENSOCUG00000021560 RPS4X Uncharacterized1:106020314-106021003 protein [Source:UniProtKB/TrEMBL;Acc:G1TT24]0.044105 1.00E-05 ENSOCUG00000001027 NOBOX NOBOX oogenesis7:7838973-7844683 homeobox [Source:HGNC0.044067733 Symbol;Acc:HGNC:22448] 1.00E-05 ENSOCUG00000017404 - UncharacterizedDraft1:101840004-101848327 protein [Source:UniProtKB/TrEMBL;Acc:G1TDM1]0.044050667 1.00E-05 ENSOCUG00000009530 NPVF neuropeptide10:10072585-10075845 VF precursor [Source:HGNC0.043921333 Symbol;Acc:HGNC:13782] 1.00E-05 ENSOCUG00000021373 - Olfactory receptor12:21898814-21899753 [Source:UniProtKB/TrEMBL;Acc:G1U7W0]0.043652 1.00E-05 ENSOCUG00000010210 CXorf22 chromosomeX:22130901-22499773 X open reading frame0.04364769 22 [Source:HGNC Symbol;Acc:HGNC:28546] 1.00E-05 ENSOCUG00000006710 NTSR1 neurotensin GL019790:10554-21354receptor 1 (high affinity)0.043629 [Source:HGNC Symbol;Acc:HGNC:8039] 1.00E-05 ENSOCUG00000015617 SLC25A31 solute carrier15:103560064-103588722 family 25 (mitochondrial0.043317067 carrier; adenine nucleotide 1.00E-05 translocator), member 31 [Source:HGNC Symbol;Acc:HGNC:25319] ENSOCUG00000025716 - Uncharacterized12:30937178-30945807 protein [Source:UniProtKB/TrEMBL;Acc:G1TL51]0.042717 1.00E-05 ENSOCUG00000011949 - Glutathione 12:42570003-42583544S-transferase [Source:UniProtKB/TrEMBL;Acc:G1T2A7]0.042677333 1.00E-05 ENSOCUG00000014487 ODF3 outer dense GL019355:63548-65528fiber of sperm tails 0.0426026673 [Source:HGNC Symbol;Acc:HGNC:19905] 1.00E-05 ENSOCUG00000003800 TAS2R3 taste receptor,GL018758:551446-552397 type 2, member 30.042549667 [Source:HGNC Symbol;Acc:HGNC:14910] 1.00E-05 ENSOCUG00000029228 LRRC19 leucine rich 1:26481673-26589887repeat containing 19 [Source:HGNC0.042456 Symbol;Acc:HGNC:23379] 1.00E-05 ENSOCUG00000011580 SPATA32 spermatogenesis19:45118994-45121758 associated 32 [Source:HGNC0.041954 Symbol;Acc:HGNC:26349] 1.00E-05 ENSOCUG00000024058 - Transporter AAGW02082878:69-9084 [Source:UniProtKB/TrEMBL;Acc:G1TQX9]0.041609667 1.00E-05 ENSOCUG00000017844 - UncharacterizedGL019892:1-5229 protein [Source:UniProtKB/TrEMBL;Acc:G1U7R7]0.041585333 1.00E-05 ENSOCUG00000027698 - UncharacterizedGL018711:4485367-4486261 protein [Source:UniProtKB/TrEMBL;Acc:G1U0L1]0.041533667 1.00E-05 ENSOCUG00000025908 - Uncharacterized1:15695234-15732091 protein [Source:UniProtKB/TrEMBL;Acc:G1TM37]0.0411413 1.00E-05 ENSOCUG00000028181 ORYCUNV1R1588UncharacterizedGL018747:208293-209196 protein [Source:UniProtKB/TrEMBL;Acc:G1TM08]0.040966667 1.00E-05 ENSOCUG00000027720 - GL018737:1980796-19815210.040956667 1.00E-05 ENSOCUG00000025601 RGS11 regulator of GL019319:1-36494G-protein signaling 11 [Source:HGNC0.04063 Symbol;Acc:HGNC:9993] 1.00E-05 ENSOCUG00000023563 - 2:22803291-228040490.040567333 1.00E-05 ENSOCUG00000025389 - 3:47619344-47620133 0.040508 1.00E-05 ENSOCUG00000007843 - paraneoplasticGL019284:47652-48771 Ma antigen family0.040460667 member 6A [Source:HGNC 1.00E-05 Symbol;Acc:HGNC:28248] ENSOCUG00000009770 CCDC83 coiled-coil domain1:130812998-130874038 containing 830.040352667 [Source:HGNC Symbol;Acc:HGNC:28535] 1.00E-05 ENSOCUG00000024155 ORYCUNV1R1604UncharacterizedGL018747:286330-287233 protein [Source:UniProtKB/TrEMBL;Acc:G1TNK0]0.039564333 1.00E-05 ENSOCUG00000010100 IL2 Oryctolagus15:98312428-98317579 cuniculus interleukin0.039459667 2 (IL2), transcript variant 1.00E-05 1, mRNA. [Source:RefSeq mRNA;Acc:NM_001163180] ENSOCUG00000008297 - proteoglycan1:190475238-190477441 2, bone marrow (natural0.039198 killer cell activator, 1.00E-05eosinophil granule major basic protein) [Source:HGNC Symbol;Acc:HGNC:9362] ENSOCUG00000003089 PRG3 proteoglycan1:190466448-190470849 3 [Source:HGNC 0.039082667Symbol;Acc:HGNC:9363] 1.00E-05 ENSOCUG00000029681 NRXN3 neurexin 3 [Source:HGNC20:26392167-26772006 Symbol;Acc:HGNC:8010]0.038894667 1.00E-05

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ENSOCUG00000024199 ORYCUNV1R1643UncharacterizedGL018763:840646-841558 protein [Source:UniProtKB/TrEMBL;Acc:G1TXP3]0.038146 1.00E-05 ENSOCUG00000014664 PLCZ1 phospholipase8:21164500-21241539 C, zeta 1 [Source:HGNC0.0378526 Symbol;Acc:HGNC:19218] 1.00E-05 ENSOCUG00000006218 - GL018700:1672767-16735160.037706333 1.00E-05 ENSOCUG00000006115 LRIT1 leucine-richGL018716:3567350-3577875 repeat, immunoglobulin-like0.037518767 and transmembrane 1.00E-05 domains 1 [Source:HGNC Symbol;Acc:HGNC:23404] ENSOCUG00000015660 TRIM31 tripartite motif12:22100313-22111018 containing 31 [Source:HGNC0.0375 Symbol;Acc:HGNC:16289] 1.00E-05 ENSOCUG00000024257 ORYCUNV1R1645UncharacterizedGL018752:633675-634581 protein [Source:UniProtKB/TrEMBL;Acc:G1TI75]0.037433333 1.00E-05 ENSOCUG00000021544 - Olfactory receptor17:42937111-42938050 [Source:UniProtKB/TrEMBL;Acc:G1U6I1]0.037337667 1.00E-05 ENSOCUG00000022038 - UncharacterizedGL019776:13708-21509 protein [Source:UniProtKB/TrEMBL;Acc:G1U3N9]0.037117667 1.00E-05 ENSOCUG00000003870 FGF19 fibroblast growthAAGW02083224:346-3867 factor 19 [Source:HGNC0.036845 Symbol;Acc:HGNC:3675] 1.00E-05 ENSOCUG00000004746 SPATA16 spermatogenesis14:67899119-68202514 associated 16 [Source:HGNC0.036621767 Symbol;Acc:HGNC:29935] 1.00E-05 ENSOCUG00000003497 SHCBP1L SHC SH2-domainGL019071:65285-96510 binding protein0.0363748 1-like [Source:HGNC Symbol;Acc:HGNC:16788] 1.00E-05 ENSOCUG00000021952 - GL018846:358069-3595460.036308333 1.00E-05 ENSOCUG00000006097 GP2 glycoprotein6:8049962-8071078 2 (zymogen granule membrane)0.036276 [Source:HGNC 1.00E-05 Symbol;Acc:HGNC:4441] ENSOCUG00000016779 SOX3 SRY (sex determiningGL018700:3705586-3706924 region Y)-box0.036211 3 [Source:HGNC Symbol;Acc:HGNC:11199] 1.00E-05 ENSOCUG00000014297 APOF apolipoprotein4:39937979-39938900 F [Source:HGNC0.035934333 Symbol;Acc:HGNC:615] 1.00E-05 ENSOCUG00000027015 - 8:91210495-91211338 0.035857 1.00E-05 ENSOCUG00000027798 - UncharacterizedGL018704:2253647-2254649 protein [Source:UniProtKB/TrEMBL;Acc:G1TYN3]0.035618667 1.00E-05 ENSOCUG00000005236 - Uncharacterized2:106395582-106728632 protein [Source:UniProtKB/TrEMBL;Acc:G1SNH4]0.035611 1.00E-05 ENSOCUG00000026072 BSG basigin (Ok 13:108452071-108452881blood group) [Source:HGNC0.035315 Symbol;Acc:HGNC:1116] 1.00E-05 ENSOCUG00000016758 - Uncharacterized2:155325055-155369579 protein [Source:UniProtKB/TrEMBL;Acc:G1TCB5]0.035272667 1.00E-05 ENSOCUG00000024564 - UncharacterizedGL018856:548914-550139 protein [Source:UniProtKB/TrEMBL;Acc:G1TYX3]0.035267 1.00E-05 ENSOCUG00000029464 - UncharacterizedGL018772:1385774-1414773 protein [Source:UniProtKB/TrEMBL;Acc:U3KNK9]0.034986 1.00E-05 ENSOCUG00000028137 IHH indianDraft hedgehog7:160289021-160436197 [Source:HGNC0.034766967 Symbol;Acc:HGNC:5956] 1.00E-05 ENSOCUG00000023672 - Uncharacterized3:153031489-153032343 protein [Source:UniProtKB/TrEMBL;Acc:G1U4E5]0.034643667 1.00E-05

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Fold_change-GroupP-value B/Group FDR F 0.973630229 1 1 0.960575093 1 1 0.951050265 1 1 0.944175404 1 1 0.940208951 1 1 0.937960523 1 1 0.934304827 1 1 0.928191928 1 1 0.911542091 1 1 0.91041562 1 1 0.904046967 1 1 0.899508356 1 1 0.883174342 1 1 0.878485668 1 1 0.874246873 1 1 0.874054532 1 1 0.867283056 1 1 0.867183612 1 1 0.862300986 1 1 0.856254719 1 1 0.850527385 1 1 Draft 0.848329327 1 1 0.84075172 1 1 0.839048959 1 1 0.836673783 1 1 0.836278728 1 1 0.834195393 1 1 0.83179883 1 1 0.830666818 1 1 0.816239587 1 1 0.813261501 1 1 0.807949739 1 1 0.793583536 1 1 0.793476138 1 1 0.792722308 1 1 0.788076229 1 1 0.787699761 1 1 0.784580242 1 1 0.784111876 1 1 0.779393969 1 1 0.777657595 1 1 0.774824884 1 1 0.774253578 1 1 0.769936386 1 1 0.769809194 1 1 0.765430929 1 1 0.760687447 1 1 0.756302019 1 1

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0.746286332 1 1 0.739460632 1 1 0.734261938 1 1 0.73359757 1 1 0.73291247 1 1 0.724913897 1 1 0.72346377 1 1 0.716567869 1 1 0.714921938 1 1 0.711337805 1 1 0.706140177 1 1 0.7049604 1 1 0.70227108 1 1 0.691286328 1 1 0.691060012 1 1 0.688006505 1 1 0.687280469 1 1 0.686152924 1 1 0.685856537 1 1 0.68177703 1 1 0.678036812 1 1 0.673754147 1 1 0.672661924 1 1 Draft 0.671666493 1 1 0.667494272 1 1 0.664803407 1 1 0.662256871 1 1 0.661133179 1 1 0.660289435 1 1 0.657557076 1 1 0.653954579 1 1 0.64841697 1 1 0.646136498 1 1 0.645911847 1 1 0.645870648 1 1 0.638424916 1 1 0.631317196 1 1 0.62921543 1 1 0.629011879 1 1 0.625372629 1 1 0.625026663 1 1 0.623899967 1 1 0.623142612 1 1 0.621806396 1 1 0.616960676 1 1 0.615636855 1 1 0.609418436 1 1 0.609104572 1 1 0.60587792 1 1 0.602370465 1 1

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0.600708216 1 1 0.598158959 1 1 0.59715337 1 1 0.595562457 1 1 0.592961011 1 1 0.591036879 1 1 0.591002159 1 1 0.590699405 1 1 0.590583986 1 1 0.587662225 1 1 0.585278592 1 1 0.584055459 1 1 0.580184717 1 1 0.579836175 1 1 0.577231658 1 1 0.575365554 1 1 0.573185124 1 1 0.572465443 1 1 0.569885145 1 1 0.559383487 1 1 0.557877954 1 1 0.55342528 1 1 0.553186843 1 1 Draft 0.552461562 1 1 0.550015342 1 1 0.548750008 1 1 0.548624851 1 1 0.54750304 1 1 0.547444558 1 1 0.546591303 1 1 0.545896889 1 1 0.545208261 1 1 0.54417843 1 1 0.544057104 1 1 0.543974034 1 1 0.541437214 1 1 0.53542274 1 1 0.533225813 1 1 0.531122841 1 1 0.525382278 1 1 0.524101894 1 1 0.516040074 1 1 0.515307995 1 1 0.515239265 1 1 0.511959749 1 1 0.510033501 1 1 0.50781481 1 1 0.505860558 1 1 0.503192105 1 1 0.501346585 1 1

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0.500533922 1 1 0.49789812 1 1 0.496009608 1 1 0.496005085 1 1 0.495918468 1 1 0.495831999 1 1 0.490177302 1 1 0.484895697 1 1 0.481305872 1 1 0.481001556 1 1 0.479537565 1 1 0.478547246 1 1 0.478392125 1 1 0.477880333 1 1 0.475311838 1 1 0.47478764 1 1 0.473825594 1 1 0.47341837 1 1 0.472265752 1 1 0.469699281 1 1 0.469629021 1 1 0.469140851 1 1 0.463192889 1 1 Draft 0.460648633 1 1 0.460367714 1 1 0.459137298 1 1 0.457611327 1 1 0.45292182 1 1 0.447920986 1 1 0.435867226 1 1 0.434449423 1 1 0.434197395 1 1 0.433802119 1 1 0.431752593 1 1 0.429571083 1 1 0.427746606 1 1 0.42503442 1 1 0.423588582 1 1 0.420195034 1 1 0.41979314 1 1 0.417880781 1 1 0.41416272 1 1 0.412894769 1 1 0.412228528 1 1 0.412120495 1 1 0.4102286 1 1 0.409005065 1 1 0.407584539 1 1 0.406031816 1 1 0.404922729 1 1

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0.404294696 1 1 0.403179968 1 1 0.402739291 1 1 0.402570912 1 1 0.400597155 1 1 0.399456554 1 1 0.398241351 1 1 0.396428736 1 1 0.394772081 1 1 0.393615764 1 1 0.391726805 1 1 0.385831343 1 1 0.385298209 1 1 0.383115644 1 1 0.380039709 1 1 0.376568492 1 1 0.376023685 1 1 0.375958592 1 1 0.374491596 1 1 0.374473783 1 1 0.37435853 1 1 0.372654531 1 1 0.371478335 1 1 Draft 0.369005544 1 1 0.364697802 1 1 0.361927866 1 1 0.360301646 1 1 0.359142053 1 1 0.35743761 1 1 0.350902887 1 1 0.347908458 1 1 0.346641181 1 1 0.343713691 1 1 0.340314542 1 1 0.33884253 1 1 0.338573117 1 1 0.337600936 1 1 0.33661734 1 1 0.334969084 1 1 0.334183043 1 1 0.334070462 1 1 0.333963401 1 1 0.333887829 1 1 0.332978482 1 1 0.326980773 1 1 0.322092185 1 1 0.320383006 1 1 0.316495393 1 1 0.315763256 1 1 0.313213641 1 1

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0.308748663 1 1 0.303471263 1 1 0.302000396 1 1 0.301985474 1 1 0.300145184 1 1 0.297681044 1 1 0.291695271 1 1 0.290462572 1 1 0.289174867 1 1 0.288661055 1 1 0.286589579 1 1 0.286490853 1 1 0.284895089 1 1 0.282827358 1 1 0.282404888 1 1 0.282111201 1 1 0.281841052 1 1 0.277296092 1 1 0.27417601 1 1 0.273450166 1 1 0.271403745 1 1 0.266197268 1 1 0.266164841 1 1 Draft 0.266152484 1 1 0.265315163 1 1 0.25596794 1 1 0.254802897 1 1 0.248534363 1 1 0.248354468 1 1 0.243398309 1 1 0.239486621 1 1 0.23717811 1 1 0.23509424 1 1 0.234159734 1 1 0.233355448 1 1 0.195180255 1 1 0.193343697 1 1 0.192823957 1 1 0.188792372 1 1 0.184054224 1 1 0.181456152 1 1 0.179298397 1 1 0.172403616 1 1 0.172174627 1 1 0.168526781 1 1 0.164078114 1 1 0.159407721 1 1 0.152662495 1 1 0.147750688 1 1 0.143057755 1 1

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0.135754454 1 1 0.131915108 1 1 0.131122933 1 1 0.129716451 1 1 0.128923115 1 1 0.128252835 1 1 0.125086424 1 1 0.109841629 1 1 0.1096919 1 1 0.104580152 1 1 0.086507011 1 1 0.076670122 1 1 0.074373329 1 1 0.032045666 1 1 8.88E-06 1 1 8.87E-06 1 1 8.76E-06 1 1 8.60E-06 1 1 8.52E-06 1 1 8.26E-06 1 1 7.55E-06 1 1 6.86E-06 1 1 6.68E-06 1 1 Draft 5.91E-06 1 1 5.58E-06 1 1 5.30E-06 1 1 4.21E-06 1 1 4.17E-06 1 1 3.91E-06 1 1 3.90E-06 1 1 3.22E-06 1 1 2.79E-06 1 1 0.431387893 0.884136 0.901302 0.43752963 0.879359 0.896485 0.381550947 0.878181 0.895337 0.398467767 0.870682 0.887743 0.458450909 0.870312 0.887418 0.33855609 0.857774 0.874685 0.429333475 0.856831 0.873775 0.392243909 0.85673 0.873724 0.341136889 0.844064 0.860857 0.317914306 0.822428 0.838839 0.503514769 0.81114 0.827472 0.476587788 0.81114 0.827472 0.461984441 0.81114 0.827472 0.305295231 0.80856 0.824889 0.430681692 0.805539 0.821856 0.423751495 0.800074 0.816328 0.388761137 0.798662 0.814935 0.374430427 0.797437 0.813734

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0.525075841 0.796658 0.813082 0.502817788 0.796658 0.813082 0.458838224 0.796658 0.813082 0.311129704 0.79159 0.808005 0.277787963 0.79159 0.808005 0.361683484 0.791229 0.807731 0.324505385 0.791229 0.807731 0.459226876 0.788942 0.805444 0.460596942 0.779099 0.795489 0.434599631 0.779099 0.795489 0.372928422 0.769626 0.785863 0.298486853 0.76697 0.783197 0.56345222 0.757224 0.773427 0.468986619 0.757224 0.773427 0.463998302 0.757224 0.773427 0.379523257 0.757224 0.773427 0.443476596 0.754436 0.770625 0.453244431 0.74227 0.758243 0.654211399 0.741603 0.75841 0.637235508 0.741603 0.75841 0.634873152 0.741603 0.75841 0.628742387 0.741603 0.75841 0.628601175 0.741603 0.75841 Draft 0.628402492 0.741603 0.75841 0.61729823 0.741603 0.75841 0.615740525 0.741603 0.75841 0.614635629 0.741603 0.75841 0.605151164 0.741603 0.75841 0.603343443 0.741603 0.75841 0.601762997 0.741603 0.75841 0.588628516 0.741603 0.75841 0.5850998 0.741603 0.75841 0.573047086 0.741603 0.75841 0.528703261 0.741603 0.75841 0.5179777 0.741603 0.75841 0.505340152 0.741603 0.75841 0.484295415 0.741603 0.75841 0.449927347 0.737348 0.754104 0.431828991 0.734638 0.751377 0.148829634 0.73331 0.750063 0.45043284 0.729925 0.746644 0.584688561 0.729103 0.746244 0.548864762 0.729103 0.746244 0.541337535 0.729103 0.746244 0.51027476 0.729103 0.746244 0.475770039 0.729103 0.746244 0.444143851 0.729103 0.746244 0.439020858 0.729103 0.746244 0.417583337 0.729103 0.746244 0.395266111 0.729103 0.746244

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0.393711686 0.729103 0.746244 0.44339955 0.726256 0.743374 0.458409779 0.719524 0.736527 0.465336781 0.711597 0.728456 0.357354955 0.709904 0.726809 0.354765814 0.709904 0.726809 0.388363648 0.705346 0.722184 0.707004195 0.700994 0.719131 0.698145483 0.700994 0.719131 0.688711245 0.700994 0.719131 0.687229057 0.700994 0.719131 0.674586923 0.700994 0.719131 0.668420355 0.700994 0.719131 0.668143261 0.700994 0.719131 0.663664783 0.700994 0.719131 0.651376422 0.700994 0.719131 0.645413245 0.700994 0.719131 0.636575663 0.700994 0.719131 0.631640963 0.700994 0.719131 0.630303026 0.700994 0.719131 0.627780442 0.700994 0.719131 0.618593182 0.700994 0.719131 0.599917102 0.700994 0.719131 Draft 0.592637432 0.700994 0.719131 0.582795646 0.700994 0.719131 0.577881062 0.700994 0.719131 0.577492807 0.700994 0.719131 0.571221002 0.700994 0.719131 0.569226754 0.700994 0.719131 0.552768308 0.700994 0.719131 0.545970704 0.700994 0.719131 0.540198705 0.700994 0.719131 0.520368925 0.700994 0.719131 0.503611023 0.700994 0.719131 0.497056211 0.700994 0.719131 0.494913738 0.700994 0.719131 0.466871704 0.700994 0.719131 0.460424051 0.700994 0.719131 0.453759489 0.700994 0.719131 0.447083412 0.700994 0.719131 0.009248952 0.681754 0.699518 1.96E-06 0.681754 0.699518 1.89E-06 0.681754 0.699518 0.179477796 0.677407 0.695387 0.134515078 0.677407 0.695387 2.41E-06 0.677407 0.695387 2.39E-06 0.677407 0.695387 2.37E-06 0.677407 0.695387 2.36E-06 0.677407 0.695387 2.23E-06 0.677407 0.695387

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2.12E-06 0.677407 0.695387 0.466757038 0.676417 0.694412 0.512917089 0.659441 0.677104 0.49756629 0.659441 0.677104 0.485634113 0.659441 0.677104 0.561614209 0.647973 0.665527 0.552514594 0.647973 0.665527 0.522273587 0.647973 0.665527 0.501941292 0.647973 0.665527 0.498941139 0.647973 0.665527 0.979560053 0.635908 0.659546 0.954243344 0.635908 0.659546 0.930161631 0.635908 0.659546 0.927534519 0.635908 0.659546 0.920061805 0.635908 0.659546 0.919964885 0.635908 0.659546 0.919548055 0.635908 0.659546 0.914423848 0.635908 0.659546 0.911947168 0.635908 0.659546 0.907295906 0.635908 0.659546 0.897560738 0.635908 0.659546 0.892174306 0.635908 0.659546 0.881206204 0.635908 0.659546 Draft 0.881066581 0.635908 0.659546 0.874235744 0.635908 0.659546 0.868327217 0.635908 0.659546 0.866353005 0.635908 0.659546 0.863330512 0.635908 0.659546 0.860386111 0.635908 0.659546 0.8596042 0.635908 0.659546 0.856062083 0.635908 0.659546 0.852927353 0.635908 0.659546 0.846742314 0.635908 0.659546 0.844893881 0.635908 0.659546 0.843941693 0.635908 0.659546 0.836639428 0.635908 0.659546 0.835620494 0.635908 0.659546 0.832635142 0.635908 0.659546 0.828957895 0.635908 0.659546 0.827460409 0.635908 0.659546 0.825249488 0.635908 0.659546 0.824886499 0.635908 0.659546 0.822244753 0.635908 0.659546 0.816255822 0.635908 0.659546 0.806125337 0.635908 0.659546 0.805684882 0.635908 0.659546 0.802902797 0.635908 0.659546 0.802816377 0.635908 0.659546 0.802689972 0.635908 0.659546 0.79719747 0.635908 0.659546

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0.796763217 0.635908 0.659546 0.790366244 0.635908 0.659546 0.789259465 0.635908 0.659546 0.787071993 0.635908 0.659546 0.772467105 0.635908 0.659546 0.768745713 0.635908 0.659546 0.76852682 0.635908 0.659546 0.768078618 0.635908 0.659546 0.766603214 0.635908 0.659546 0.764719905 0.635908 0.659546 0.763505597 0.635908 0.659546 0.760740436 0.635908 0.659546 0.760724265 0.635908 0.659546 0.757149032 0.635908 0.659546 0.751473121 0.635908 0.659546 0.749798868 0.635908 0.659546 0.746394886 0.635908 0.659546 0.745384709 0.635908 0.659546 0.742564171 0.635908 0.659546 0.741355703 0.635908 0.659546 0.738412839 0.635908 0.659546 0.738084441 0.635908 0.659546 0.736289277 0.635908 0.659546 Draft 0.735659134 0.635908 0.659546 0.731859138 0.635908 0.659546 0.73150954 0.635908 0.659546 0.728157972 0.635908 0.659546 0.724247565 0.635908 0.659546 0.720240185 0.635908 0.659546 0.718375353 0.635908 0.659546 0.718069664 0.635908 0.659546 0.715464146 0.635908 0.659546 0.715094185 0.635908 0.659546 0.714401584 0.635908 0.659546 0.713589481 0.635908 0.659546 0.712658491 0.635908 0.659546 0.70418378 0.635908 0.659546 0.702193348 0.635908 0.659546 0.702024033 0.635908 0.659546 0.701676496 0.635908 0.659546 0.700257267 0.635908 0.659546 0.700153534 0.635908 0.659546 0.699422869 0.635908 0.659546 0.698536441 0.635908 0.659546 0.69754498 0.635908 0.659546 0.694052184 0.635908 0.659546 0.690823137 0.635908 0.659546 0.690548246 0.635908 0.659546 0.690048474 0.635908 0.659546 0.688423247 0.635908 0.659546

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0.687230595 0.635908 0.659546 0.686097279 0.635908 0.659546 0.685246444 0.635908 0.659546 0.684920903 0.635908 0.659546 0.683456848 0.635908 0.659546 0.682847574 0.635908 0.659546 0.680784427 0.635908 0.659546 0.6746848 0.635908 0.659546 0.667264988 0.635908 0.659546 0.665864266 0.635908 0.659546 0.664380079 0.635908 0.659546 0.663754231 0.635908 0.659546 0.661966339 0.635908 0.659546 0.660549303 0.635908 0.659546 0.659383982 0.635908 0.659546 0.658315724 0.635908 0.659546 0.657378231 0.635908 0.659546 0.65621023 0.635908 0.659546 0.655574202 0.635908 0.659546 0.655279672 0.635908 0.659546 0.654260884 0.635908 0.659546 0.653097226 0.635908 0.659546 0.652534568 0.635908 0.659546 Draft 0.65156646 0.635908 0.659546 0.650267797 0.635908 0.659546 0.648901244 0.635908 0.659546 0.641789825 0.635908 0.659546 0.641332293 0.635908 0.659546 0.640363502 0.635908 0.659546 0.639368206 0.635908 0.659546 0.632767091 0.635908 0.659546 0.622730627 0.635908 0.659546 0.618795408 0.635908 0.659546 0.617213198 0.635908 0.659546 0.616144843 0.635908 0.659546 0.614004304 0.635908 0.659546 0.61062894 0.635908 0.659546 0.601134529 0.635908 0.659546 0.591715178 0.635908 0.659546 0.585860638 0.635908 0.659546 0.585276977 0.635908 0.659546 0.581825001 0.635908 0.659546 0.579406884 0.635908 0.659546 0.573884444 0.635908 0.659546 0.568142099 0.635908 0.659546 0.566745044 0.635908 0.659546 0.557125826 0.635908 0.659546 0.547634259 0.635908 0.659546 0.544053092 0.635908 0.659546 0.540287408 0.635908 0.659546

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0.533877729 0.635908 0.659546 0.533036028 0.635908 0.659546 0.532741401 0.635908 0.659546 0.532352949 0.635908 0.659546 0.53187826 0.635908 0.659546 0.528025887 0.635908 0.659546 0.527204173 0.635908 0.659546 0.524677639 0.635908 0.659546 0.52385264 0.635908 0.659546 0.521139293 0.635908 0.659546 0.517027027 0.635908 0.659546 0.516672354 0.635908 0.659546 0.514129194 0.635908 0.659546 0.509904807 0.635908 0.659546 0.508286072 0.635908 0.659546 0.503038714 0.635908 0.659546 0.466441922 0.635908 0.659546 0.459061585 0.635908 0.659546 0.452635413 0.635908 0.659546 0.450691435 0.635908 0.659546 0.408716583 0.635908 0.659546 0.406098129 0.635908 0.659546 0.396061657 0.635908 0.659546 Draft 0.339625127 0.635908 0.659546 0.391815272 0.63289 0.656456 0.47607039 0.630554 0.654071 0.552909498 0.625855 0.649275 0.500484646 0.625855 0.649275 0.278286129 0.615365 0.638431 0.515670515 0.60088 0.623477 0.480851217 0.60088 0.623477 0.577432297 0.60034 0.622992 0.55773238 0.60034 0.622992 0.450096962 0.600255 0.622941 0.528293503 0.59372 0.616344 0.524217383 0.59372 0.616344 0.515637334 0.59372 0.616344 0.501858624 0.59372 0.616344 0.490446142 0.59372 0.616344 0.509321359 0.588486 0.610983 0.469490488 0.588486 0.610983 1.804028348 0.586647 0.628934 1.74778345 0.586647 0.628934 1.710667551 0.586647 0.628934 1.683156537 0.586647 0.628934 1.636914446 0.586647 0.628934 1.564910924 0.586647 0.628934 1.560701091 0.586647 0.628934 1.552861133 0.586647 0.628934 1.54458102 0.586647 0.628934

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1.543639889 0.586647 0.628934 1.536693325 0.586647 0.628934 1.508231499 0.586647 0.628934 1.475901239 0.586647 0.628934 1.463630625 0.586647 0.628934 1.455579604 0.586647 0.628934 1.451005848 0.586647 0.628934 1.443682924 0.586647 0.628934 1.429237667 0.586647 0.628934 1.409901616 0.586647 0.628934 1.407720431 0.586647 0.628934 1.407397003 0.586647 0.628934 1.39982754 0.586647 0.628934 1.393951654 0.586647 0.628934 1.393933086 0.586647 0.628934 1.393800894 0.586647 0.628934 1.392597236 0.586647 0.628934 1.391634391 0.586647 0.628934 1.38759313 0.586647 0.628934 1.386709032 0.586647 0.628934 1.383497581 0.586647 0.628934 1.361759613 0.586647 0.628934 1.360874276 0.586647 0.628934 Draft 1.35587124 0.586647 0.628934 1.349087036 0.586647 0.628934 1.348917814 0.586647 0.628934 1.344306324 0.586647 0.628934 1.333833197 0.586647 0.628934 1.326204076 0.586647 0.628934 1.324705605 0.586647 0.628934 1.324691523 0.586647 0.628934 1.323704614 0.586647 0.628934 1.32206414 0.586647 0.628934 1.312803649 0.586647 0.628934 1.309672481 0.586647 0.628934 1.305537399 0.586647 0.628934 1.304989475 0.586647 0.628934 1.304074069 0.586647 0.628934 1.302302558 0.586647 0.628934 1.298956136 0.586647 0.628934 1.297821681 0.586647 0.628934 1.295943169 0.586647 0.628934 1.29473119 0.586647 0.628934 1.294560144 0.586647 0.628934 1.290135386 0.586647 0.628934 1.289918619 0.586647 0.628934 1.287139742 0.586647 0.628934 1.282725266 0.586647 0.628934 1.282448663 0.586647 0.628934 1.280787288 0.586647 0.628934

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1.27746558 0.586647 0.628934 1.276348259 0.586647 0.628934 1.276217776 0.586647 0.628934 1.275383915 0.586647 0.628934 1.273540614 0.586647 0.628934 1.270769267 0.586647 0.628934 1.267471929 0.586647 0.628934 1.26673036 0.586647 0.628934 1.263990758 0.586647 0.628934 1.263584258 0.586647 0.628934 1.257745633 0.586647 0.628934 1.250308767 0.586647 0.628934 1.243409112 0.586647 0.628934 1.239247878 0.586647 0.628934 1.239153496 0.586647 0.628934 1.238412887 0.586647 0.628934 1.235809876 0.586647 0.628934 1.23034631 0.586647 0.628934 1.229777491 0.586647 0.628934 1.226851188 0.586647 0.628934 1.218646384 0.586647 0.628934 1.218190341 0.586647 0.628934 1.218058885 0.586647 0.628934 Draft 1.216491598 0.586647 0.628934 1.215229071 0.586647 0.628934 1.211797248 0.586647 0.628934 1.211310596 0.586647 0.628934 1.209795682 0.586647 0.628934 1.200013755 0.586647 0.628934 1.199226674 0.586647 0.628934 1.195786343 0.586647 0.628934 1.194971307 0.586647 0.628934 1.193560867 0.586647 0.628934 1.191930649 0.586647 0.628934 1.191520101 0.586647 0.628934 1.18737514 0.586647 0.628934 1.186482016 0.586647 0.628934 1.179992891 0.586647 0.628934 1.178414017 0.586647 0.628934 1.176908657 0.586647 0.628934 1.175177057 0.586647 0.628934 1.175143013 0.586647 0.628934 1.17483676 0.586647 0.628934 1.171480679 0.586647 0.628934 1.171454916 0.586647 0.628934 1.168112164 0.586647 0.628934 1.167404572 0.586647 0.628934 1.163948428 0.586647 0.628934 1.163332461 0.586647 0.628934 1.162569321 0.586647 0.628934

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1.161951294 0.586647 0.628934 1.15648209 0.586647 0.628934 1.155995426 0.586647 0.628934 1.154687229 0.586647 0.628934 1.153591448 0.586647 0.628934 1.151865818 0.586647 0.628934 1.14749084 0.586647 0.628934 1.146579993 0.586647 0.628934 1.145532936 0.586647 0.628934 1.143580209 0.586647 0.628934 1.139745558 0.586647 0.628934 1.138960186 0.586647 0.628934 1.13608804 0.586647 0.628934 1.13291687 0.586647 0.628934 1.131686308 0.586647 0.628934 1.131228499 0.586647 0.628934 1.129443338 0.586647 0.628934 1.127512995 0.586647 0.628934 1.12562572 0.586647 0.628934 1.123285244 0.586647 0.628934 1.121702643 0.586647 0.628934 1.119784103 0.586647 0.628934 1.113064079 0.586647 0.628934 Draft 1.111308163 0.586647 0.628934 1.109106426 0.586647 0.628934 1.108088029 0.586647 0.628934 1.106312773 0.586647 0.628934 1.105241856 0.586647 0.628934 1.102740298 0.586647 0.628934 1.102624804 0.586647 0.628934 1.10133338 0.586647 0.628934 1.100676114 0.586647 0.628934 1.100639158 0.586647 0.628934 1.098913829 0.586647 0.628934 1.097587832 0.586647 0.628934 1.097002916 0.586647 0.628934 1.096166522 0.586647 0.628934 1.095987053 0.586647 0.628934 1.095121909 0.586647 0.628934 1.09375497 0.586647 0.628934 1.092316054 0.586647 0.628934 1.092072907 0.586647 0.628934 1.090637729 0.586647 0.628934 1.090575324 0.586647 0.628934 1.088998469 0.586647 0.628934 1.08867214 0.586647 0.628934 1.08853698 0.586647 0.628934 1.081451313 0.586647 0.628934 1.078449098 0.586647 0.628934 1.0780741 0.586647 0.628934

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1.076811905 0.586647 0.628934 1.07634606 0.586647 0.628934 1.070473437 0.586647 0.628934 1.069571735 0.586647 0.628934 1.069353964 0.586647 0.628934 1.068900969 0.586647 0.628934 1.066570578 0.586647 0.628934 1.066056814 0.586647 0.628934 1.064770889 0.586647 0.628934 1.064138935 0.586647 0.628934 1.063202685 0.586647 0.628934 1.06156592 0.586647 0.628934 1.061522016 0.586647 0.628934 1.061197951 0.586647 0.628934 1.059335007 0.586647 0.628934 1.058081073 0.586647 0.628934 1.058030048 0.586647 0.628934 1.057139751 0.586647 0.628934 1.056838019 0.586647 0.628934 1.054819574 0.586647 0.628934 1.054685669 0.586647 0.628934 1.054648818 0.586647 0.628934 1.054379124 0.586647 0.628934 Draft 1.054212579 0.586647 0.628934 1.053241725 0.586647 0.628934 1.048535175 0.586647 0.628934 1.045965606 0.586647 0.628934 1.044694062 0.586647 0.628934 1.04291983 0.586647 0.628934 1.041736699 0.586647 0.628934 1.040690198 0.586647 0.628934 1.038808554 0.586647 0.628934 1.038661664 0.586647 0.628934 1.037687376 0.586647 0.628934 1.035871392 0.586647 0.628934 1.034957781 0.586647 0.628934 1.034649455 0.586647 0.628934 1.034476235 0.586647 0.628934 1.034463794 0.586647 0.628934 1.033614675 0.586647 0.628934 1.033285918 0.586647 0.628934 1.031351263 0.586647 0.628934 1.031124011 0.586647 0.628934 1.030790852 0.586647 0.628934 1.028519905 0.586647 0.628934 1.027692238 0.586647 0.628934 1.027476754 0.586647 0.628934 1.025783422 0.586647 0.628934 1.025493302 0.586647 0.628934 1.024335078 0.586647 0.628934

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1.021597409 0.586647 0.628934 1.021132237 0.586647 0.628934 1.020864353 0.586647 0.628934 1.020675911 0.586647 0.628934 1.019485314 0.586647 0.628934 1.018646076 0.586647 0.628934 1.01820278 0.586647 0.628934 1.017338041 0.586647 0.628934 1.015806066 0.586647 0.628934 1.015323014 0.586647 0.628934 1.014431491 0.586647 0.628934 1.012870995 0.586647 0.628934 1.012240239 0.586647 0.628934 1.00955891 0.586647 0.628934 1.008003197 0.586647 0.628934 1.007029661 0.586647 0.628934 1.006972185 0.586647 0.628934 1.006833514 0.586647 0.628934 1.00660737 0.586647 0.628934 1.0049162 0.586647 0.628934 1.003574112 0.586647 0.628934 1.003516902 0.586647 0.628934 1.003078904 0.586647 0.628934 Draft 1.002851303 0.586647 0.628934 1.001321687 0.586647 0.628934 1.001257902 0.586647 0.628934 1.000774903 0.586647 0.628934 0.999360546 0.586647 0.628934 0.99753581 0.586647 0.628934 0.997431537 0.586647 0.628934 0.995900116 0.586647 0.628934 0.995641923 0.586647 0.628934 0.994579677 0.586647 0.628934 0.994526693 0.586647 0.628934 0.992597811 0.586647 0.628934 0.992181723 0.586647 0.628934 0.991416927 0.586647 0.628934 0.990972047 0.586647 0.628934 0.988838911 0.586647 0.628934 0.988725258 0.586647 0.628934 0.987432433 0.586647 0.628934 0.987019943 0.586647 0.628934 0.985520829 0.586647 0.628934 0.985119739 0.586647 0.628934 0.984870014 0.586647 0.628934 0.984636505 0.586647 0.628934 0.981394003 0.586647 0.628934 0.978596045 0.586647 0.628934 0.978272458 0.586647 0.628934 0.978045165 0.586647 0.628934

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0.977671817 0.586647 0.628934 0.976698455 0.586647 0.628934 0.974850019 0.586647 0.628934 0.97459428 0.586647 0.628934 0.973585832 0.586647 0.628934 0.972842574 0.586647 0.628934 0.97225527 0.586647 0.628934 0.97223702 0.586647 0.628934 0.972190783 0.586647 0.628934 0.971608848 0.586647 0.628934 0.971099733 0.586647 0.628934 0.971069787 0.586647 0.628934 0.969479587 0.586647 0.628934 0.968686165 0.586647 0.628934 0.968495191 0.586647 0.628934 0.968348852 0.586647 0.628934 0.966125784 0.586647 0.628934 0.965938138 0.586647 0.628934 0.965561464 0.586647 0.628934 0.96550826 0.586647 0.628934 0.965290393 0.586647 0.628934 0.963958119 0.586647 0.628934 0.961598252 0.586647 0.628934 Draft 0.960736838 0.586647 0.628934 0.96063103 0.586647 0.628934 0.959852203 0.586647 0.628934 0.958854358 0.586647 0.628934 0.957438384 0.586647 0.628934 0.956801172 0.586647 0.628934 0.955538636 0.586647 0.628934 0.955008859 0.586647 0.628934 0.954714729 0.586647 0.628934 0.954450783 0.586647 0.628934 0.95414415 0.586647 0.628934 0.953793982 0.586647 0.628934 0.952576789 0.586647 0.628934 0.952324832 0.586647 0.628934 0.951759017 0.586647 0.628934 0.95174955 0.586647 0.628934 0.951242064 0.586647 0.628934 0.951077999 0.586647 0.628934 0.950575016 0.586647 0.628934 0.950080654 0.586647 0.628934 0.950071292 0.586647 0.628934 0.94993415 0.586647 0.628934 0.948867547 0.586647 0.628934 0.948041434 0.586647 0.628934 0.946215132 0.586647 0.628934 0.94562288 0.586647 0.628934 0.945579619 0.586647 0.628934

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0.945542751 0.586647 0.628934 0.945107172 0.586647 0.628934 0.945017363 0.586647 0.628934 0.943716646 0.586647 0.628934 0.942426549 0.586647 0.628934 0.94235362 0.586647 0.628934 0.940396914 0.586647 0.628934 0.938938314 0.586647 0.628934 0.938749557 0.586647 0.628934 0.938422482 0.586647 0.628934 0.936480261 0.586647 0.628934 0.93571384 0.586647 0.628934 0.935216995 0.586647 0.628934 0.931443295 0.586647 0.628934 0.931057407 0.586647 0.628934 0.930937568 0.586647 0.628934 0.929800356 0.586647 0.628934 0.929718859 0.586647 0.628934 0.928506633 0.586647 0.628934 0.925909119 0.586647 0.628934 0.924151068 0.586647 0.628934 0.923898723 0.586647 0.628934 0.923493214 0.586647 0.628934 Draft 0.922649914 0.586647 0.628934 0.92065775 0.586647 0.628934 0.920463588 0.586647 0.628934 0.919342315 0.586647 0.628934 0.919311517 0.586647 0.628934 0.917581956 0.586647 0.628934 0.917294534 0.586647 0.628934 0.916186803 0.586647 0.628934 0.915385412 0.586647 0.628934 0.914438258 0.586647 0.628934 0.914191534 0.586647 0.628934 0.913876673 0.586647 0.628934 0.912480728 0.586647 0.628934 0.912248586 0.586647 0.628934 0.911840333 0.586647 0.628934 0.910959879 0.586647 0.628934 0.910348324 0.586647 0.628934 0.908833455 0.586647 0.628934 0.908820165 0.586647 0.628934 0.907180318 0.586647 0.628934 0.906360167 0.586647 0.628934 0.906259706 0.586647 0.628934 0.905698025 0.586647 0.628934 0.903539488 0.586647 0.628934 0.903126993 0.586647 0.628934 0.89997386 0.586647 0.628934 0.899802022 0.586647 0.628934

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0.899179245 0.586647 0.628934 0.89872184 0.586647 0.628934 0.898668985 0.586647 0.628934 0.897425221 0.586647 0.628934 0.897213567 0.586647 0.628934 0.894576758 0.586647 0.628934 0.892732988 0.586647 0.628934 0.892719855 0.586647 0.628934 0.892170372 0.586647 0.628934 0.891593326 0.586647 0.628934 0.89091559 0.586647 0.628934 0.890203464 0.586647 0.628934 0.88785771 0.586647 0.628934 0.887772791 0.586647 0.628934 0.887760088 0.586647 0.628934 0.886660377 0.586647 0.628934 0.886005889 0.586647 0.628934 0.885862361 0.586647 0.628934 0.885013128 0.586647 0.628934 0.88483823 0.586647 0.628934 0.884711122 0.586647 0.628934 0.883079142 0.586647 0.628934 0.882260501 0.586647 0.628934 Draft 0.879958227 0.586647 0.628934 0.879924406 0.586647 0.628934 0.876190888 0.586647 0.628934 0.874412084 0.586647 0.628934 0.874291415 0.586647 0.628934 0.872605406 0.586647 0.628934 0.867564063 0.586647 0.628934 0.867360634 0.586647 0.628934 0.864984493 0.586647 0.628934 0.864471537 0.586647 0.628934 0.862929594 0.586647 0.628934 0.860608296 0.586647 0.628934 0.860363192 0.586647 0.628934 0.858203659 0.586647 0.628934 0.858042176 0.586647 0.628934 0.856224392 0.586647 0.628934 0.856013422 0.586647 0.628934 0.855705296 0.586647 0.628934 0.854857175 0.586647 0.628934 0.854257121 0.586647 0.628934 0.854114476 0.586647 0.628934 0.853588575 0.586647 0.628934 0.853110633 0.586647 0.628934 0.852810184 0.586647 0.628934 0.85043707 0.586647 0.628934 0.849432541 0.586647 0.628934 0.848237161 0.586647 0.628934

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0.846117446 0.586647 0.628934 0.842294201 0.586647 0.628934 0.840545539 0.586647 0.628934 0.838669548 0.586647 0.628934 0.836770953 0.586647 0.628934 0.835924287 0.586647 0.628934 0.835052606 0.586647 0.628934 0.834668235 0.586647 0.628934 0.834439654 0.586647 0.628934 0.834344164 0.586647 0.628934 0.834245332 0.586647 0.628934 0.833410285 0.586647 0.628934 0.832451906 0.586647 0.628934 0.832411163 0.586647 0.628934 0.83133762 0.586647 0.628934 0.831222359 0.586647 0.628934 0.82818075 0.586647 0.628934 0.82591626 0.586647 0.628934 0.823229267 0.586647 0.628934 0.822282643 0.586647 0.628934 0.821924895 0.586647 0.628934 0.820306749 0.586647 0.628934 0.819538702 0.586647 0.628934 Draft 0.818117465 0.586647 0.628934 0.817472799 0.586647 0.628934 0.813558341 0.586647 0.628934 0.809343107 0.586647 0.628934 0.808560755 0.586647 0.628934 0.808015157 0.586647 0.628934 0.807943359 0.586647 0.628934 0.807770103 0.586647 0.628934 0.806163926 0.586647 0.628934 0.805824325 0.586647 0.628934 0.804530136 0.586647 0.628934 0.80447358 0.586647 0.628934 0.797613845 0.586647 0.628934 0.795680178 0.586647 0.628934 0.788658353 0.586647 0.628934 0.787537755 0.586647 0.628934 0.784645726 0.586647 0.628934 0.784550352 0.586647 0.628934 0.78276583 0.586647 0.628934 0.781866256 0.586647 0.628934 0.780986026 0.586647 0.628934 0.780172496 0.586647 0.628934 0.77736667 0.586647 0.628934 0.775001599 0.586647 0.628934 0.774548549 0.586647 0.628934 0.773272899 0.586647 0.628934 0.77170172 0.586647 0.628934

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0.770067881 0.586647 0.628934 0.769430537 0.586647 0.628934 0.768642 0.586647 0.628934 0.763847873 0.586647 0.628934 0.758184005 0.586647 0.628934 0.757368812 0.586647 0.628934 0.755085474 0.586647 0.628934 0.751286965 0.586647 0.628934 0.748558477 0.586647 0.628934 0.748467805 0.586647 0.628934 0.745246033 0.586647 0.628934 0.743051751 0.586647 0.628934 0.741500067 0.586647 0.628934 0.740324561 0.586647 0.628934 0.735592456 0.586647 0.628934 0.731002292 0.586647 0.628934 0.73053385 0.586647 0.628934 0.721972468 0.586647 0.628934 0.721328936 0.586647 0.628934 0.717695572 0.586647 0.628934 0.717182931 0.586647 0.628934 0.716997474 0.586647 0.628934 0.715414309 0.586647 0.628934 Draft 0.714928704 0.586647 0.628934 0.713898412 0.586647 0.628934 0.713816922 0.586647 0.628934 0.712290104 0.586647 0.628934 0.709824206 0.586647 0.628934 0.709730539 0.586647 0.628934 0.708723608 0.586647 0.628934 0.70805492 0.586647 0.628934 0.701685593 0.586647 0.628934 0.701349581 0.586647 0.628934 0.700057807 0.586647 0.628934 0.697522435 0.586647 0.628934 0.697471681 0.586647 0.628934 0.696314611 0.586647 0.628934 0.696191251 0.586647 0.628934 0.695357849 0.586647 0.628934 0.694704933 0.586647 0.628934 0.693146279 0.586647 0.628934 0.680163584 0.586647 0.628934 0.678949743 0.586647 0.628934 0.678772023 0.586647 0.628934 0.666161659 0.586647 0.628934 0.664964892 0.586647 0.628934 0.66088912 0.586647 0.628934 0.659101114 0.586647 0.628934 0.649401753 0.586647 0.628934 0.647036566 0.586647 0.628934

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0.639685473 0.586647 0.628934 0.636777136 0.586647 0.628934 0.636298634 0.586647 0.628934 0.635861659 0.586647 0.628934 0.631941946 0.586647 0.628934 0.626102966 0.586647 0.628934 0.623329289 0.586647 0.628934 0.622448499 0.586647 0.628934 0.620679415 0.586647 0.628934 0.620401599 0.586647 0.628934 0.614653579 0.586647 0.628934 0.614295534 0.586647 0.628934 0.611937369 0.586647 0.628934 0.600984754 0.586647 0.628934 0.597024487 0.586647 0.628934 0.596416297 0.586647 0.628934 0.567940374 0.586647 0.628934 0.55730994 0.586647 0.628934 0.661107692 0.583682 0.626065 0.63287433 0.583682 0.626065 0.623252731 0.583682 0.626065 0.620271827 0.583682 0.626065 0.601108707 0.583682 0.626065 Draft 0.59786428 0.583682 0.626065 0.577676842 0.583682 0.626065 0.521525131 0.583682 0.626065 0.344072732 0.57966 0.621789 0.503635905 0.578834 0.620942 0.18259128 0.575412 0.617309 0.302551 0.573288 0.615107 0.288056033 0.573288 0.615107 0.583844362 0.570655 0.61251 0.559829779 0.570655 0.61251 0.558567462 0.570655 0.61251 0.494097977 0.570655 0.61251 0.484779921 0.570655 0.61251 0.478872552 0.570655 0.61251 0.381724918 0.564821 0.606285 0.703799028 0.544572 0.584804 0.657446346 0.544572 0.584804 0.633828212 0.544572 0.584804 0.594041144 0.544572 0.584804 0.576129385 0.544572 0.584804 0.573975388 0.544572 0.584804 0.515048115 0.544572 0.584804 0.540157918 0.534378 0.573892 0.508196248 0.531752 0.571107 0.177963739 0.528278 0.567411 0.267908147 0.528204 0.567367 0.507137887 0.528126 0.567318

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0.193295642 0.525001 0.563996 0.489369722 0.513018 0.551157 0.536768437 0.512101 0.550206 94461.3333 0.503454 0.7295 89434 0.503454 0.7295 87308 0.503454 0.7295 76317.6667 0.503454 0.7295 68456.7667 0.503454 0.7295 64312.3333 0.503454 0.7295 62377.9 0.503454 0.7295 60682.3667 0.503454 0.7295 57816.6667 0.503454 0.7295 57167.3333 0.503454 0.7295 53376.6667 0.503454 0.7295 53303.5667 0.503454 0.7295 52346.3333 0.503454 0.7295 51198.6667 0.503454 0.7295 50714.6667 0.503454 0.7295 49603 0.503454 0.7295 49232 0.503454 0.7295 48413.0667 0.503454 0.7295 48398.6667 0.503454 0.7295 47352.6667 0.503454 0.7295 Draft 44862.6667 0.503454 0.7295 43234.7333 0.503454 0.7295 42964 0.503454 0.7295 42898 0.503454 0.7295 42780.3333 0.503454 0.7295 41519.3333 0.503454 0.7295 40494.0333 0.503454 0.7295 40432 0.503454 0.7295 40309 0.503454 0.7295 39442.6667 0.503454 0.7295 39415.3333 0.503454 0.7295 39067.1667 0.503454 0.7295 38875.3333 0.503454 0.7295 38512 0.503454 0.7295 38012.3333 0.503454 0.7295 37504.6667 0.503454 0.7295 35730.8667 0.503454 0.7295 35397.4667 0.503454 0.7295 35326 0.503454 0.7295 35203.6667 0.503454 0.7295 34825 0.503454 0.7295 34777.0667 0.503454 0.7295 34542 0.503454 0.7295 34336.6667 0.503454 0.7295 33903.3333 0.503454 0.7295 33478.6333 0.503454 0.7295 33450.8667 0.503454 0.7295

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33421.0333 0.503454 0.7295 32690.5667 0.503454 0.7295 32496.8333 0.503454 0.7295 31353.8 0.503454 0.7295 30824.5 0.503454 0.7295 30357.4 0.503454 0.7295 30150.7333 0.503454 0.7295 30104.4333 0.503454 0.7295 29089 0.503454 0.7295 27961.9333 0.503454 0.7295 27654.1667 0.503454 0.7295 27367.9333 0.503454 0.7295 27104.6333 0.503454 0.7295 25970.1667 0.503454 0.7295 25835 0.503454 0.7295 25396.3667 0.503454 0.7295 25333.3 0.503454 0.7295 25227.1333 0.503454 0.7295 25112.5 0.503454 0.7295 24890.6667 0.503454 0.7295 24771.5333 0.503454 0.7295 24062.8 0.503454 0.7295 24019.6667 0.503454 0.7295 Draft 23939.6 0.503454 0.7295 23865.4667 0.503454 0.7295 23806.8667 0.503454 0.7295 23377.0333 0.503454 0.7295 23253.2667 0.503454 0.7295 23221.6667 0.503454 0.7295 23145.5 0.503454 0.7295 22770.9333 0.503454 0.7295 22579.7 0.503454 0.7295 22482.9333 0.503454 0.7295 22320.3667 0.503454 0.7295 22311.9 0.503454 0.7295 21516.7 0.503454 0.7295 21163.1 0.503454 0.7295 21154.4333 0.503454 0.7295 20581.9 0.503454 0.7295 20574.4 0.503454 0.7295 20178.4333 0.503454 0.7295 19884.6 0.503454 0.7295 19678.3333 0.503454 0.7295 19593.0667 0.503454 0.7295 19431.7333 0.503454 0.7295 18685.4333 0.503454 0.7295 18557.5 0.503454 0.7295 18313.3667 0.503454 0.7295 18118.1667 0.503454 0.7295 18086.9 0.503454 0.7295

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18048.3667 0.503454 0.7295 17696.7 0.503454 0.7295 17694.7 0.503454 0.7295 17380.6667 0.503454 0.7295 17141.2 0.503454 0.7295 16788.7333 0.503454 0.7295 16636.4 0.503454 0.7295 16610.3 0.503454 0.7295 16536.7333 0.503454 0.7295 16333.6667 0.503454 0.7295 15478.7667 0.503454 0.7295 15256.3 0.503454 0.7295 15099.5667 0.503454 0.7295 15094.0333 0.503454 0.7295 15001.3333 0.503454 0.7295 14521 0.503454 0.7295 14402.2333 0.503454 0.7295 14379.6 0.503454 0.7295 14284.5333 0.503454 0.7295 14252.9333 0.503454 0.7295 14112.2667 0.503454 0.7295 14077.6333 0.503454 0.7295 14050.9333 0.503454 0.7295 Draft 13988.0667 0.503454 0.7295 13953.6 0.503454 0.7295 13949.5333 0.503454 0.7295 13908.0333 0.503454 0.7295 13797.3 0.503454 0.7295 13789.2333 0.503454 0.7295 13557.2 0.503454 0.7295 13442.1 0.503454 0.7295 13397.7333 0.503454 0.7295 13296.6 0.503454 0.7295 13277.5 0.503454 0.7295 12827.3333 0.503454 0.7295 12818.0333 0.503454 0.7295 12757.5333 0.503454 0.7295 12736.99 0.503454 0.7295 12567.9 0.503454 0.7295 12546.4667 0.503454 0.7295 12479.3333 0.503454 0.7295 12293.5667 0.503454 0.7295 12241.3333 0.503454 0.7295 12151.3333 0.503454 0.7295 12111.6 0.503454 0.7295 12105.9333 0.503454 0.7295 12029.6567 0.503454 0.7295 11993.65 0.503454 0.7295 11952.6667 0.503454 0.7295 11913.1667 0.503454 0.7295

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11896.1667 0.503454 0.7295 11882.2667 0.503454 0.7295 11827.0667 0.503454 0.7295 11787.7333 0.503454 0.7295 11698 0.503454 0.7295 11657.9767 0.503454 0.7295 11351 0.503454 0.7295 11167.9333 0.503454 0.7295 11163.7333 0.503454 0.7295 11052.0333 0.503454 0.7295 10998.1 0.503454 0.7295 10865.8 0.503454 0.7295 10858.1667 0.503454 0.7295 10750.3333 0.503454 0.7295 10695.7667 0.503454 0.7295 10677.4667 0.503454 0.7295 10618.0667 0.503454 0.7295 10600.5 0.503454 0.7295 10374.8 0.503454 0.7295 10356.8 0.503454 0.7295 10213.7333 0.503454 0.7295 10130.7333 0.503454 0.7295 10109.8333 0.503454 0.7295 Draft 9990.8333 0.503454 0.7295 9953.8 0.503454 0.7295 9934.15 0.503454 0.7295 9926.8333 0.503454 0.7295 9864.3 0.503454 0.7295 9809.9333 0.503454 0.7295 9653.0333 0.503454 0.7295 9600.3333 0.503454 0.7295 9566.0667 0.503454 0.7295 9564.7 0.503454 0.7295 9536.2333 0.503454 0.7295 9356.8333 0.503454 0.7295 9262.4 0.503454 0.7295 9240.8667 0.503454 0.7295 9233.3333 0.503454 0.7295 9223.5667 0.503454 0.7295 9206.4267 0.503454 0.7295 9182 0.503454 0.7295 9150.9 0.503454 0.7295 9147.9 0.503454 0.7295 9135.53 0.503454 0.7295 9044.5667 0.503454 0.7295 9042.5 0.503454 0.7295 8993.9967 0.503454 0.7295 8970.9 0.503454 0.7295 8950.6 0.503454 0.7295 8904.4667 0.503454 0.7295

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8824.4667 0.503454 0.7295 8625.5667 0.503454 0.7295 8556.0667 0.503454 0.7295 8554.8 0.503454 0.7295 8519.5 0.503454 0.7295 8364.0667 0.503454 0.7295 8327.2667 0.503454 0.7295 8150.6667 0.503454 0.7295 8141.9 0.503454 0.7295 8108.7 0.503454 0.7295 8106.1333 0.503454 0.7295 8021.3667 0.503454 0.7295 7937.7333 0.503454 0.7295 7877.4667 0.503454 0.7295 7835.3 0.503454 0.7295 7787.32 0.503454 0.7295 7737.1333 0.503454 0.7295 7654.0667 0.503454 0.7295 7639.9 0.503454 0.7295 7596.1333 0.503454 0.7295 7572.6667 0.503454 0.7295 7551.1333 0.503454 0.7295 7502.7333 0.503454 0.7295 Draft 7480.5667 0.503454 0.7295 7456.5667 0.503454 0.7295 7389.2667 0.503454 0.7295 7349.7333 0.503454 0.7295 7260.2 0.503454 0.7295 7250 0.503454 0.7295 7207.4 0.503454 0.7295 7205.8633 0.503454 0.7295 7186.2733 0.503454 0.7295 7174.3933 0.503454 0.7295 7102.6667 0.503454 0.7295 7101.38 0.503454 0.7295 7084.9333 0.503454 0.7295 7078.9 0.503454 0.7295 7022.5333 0.503454 0.7295 6995.2667 0.503454 0.7295 6937.4667 0.503454 0.7295 6917.1 0.503454 0.7295 6904.6 0.503454 0.7295 6902.4667 0.503454 0.7295 6884.7333 0.503454 0.7295 6880.5 0.503454 0.7295 6878.4667 0.503454 0.7295 6853.1333 0.503454 0.7295 6765.3 0.503454 0.7295 6758.7667 0.503454 0.7295 6718.3 0.503454 0.7295

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6685.5667 0.503454 0.7295 6665.3 0.503454 0.7295 6639.4667 0.503454 0.7295 6616.6533 0.503454 0.7295 6605.9333 0.503454 0.7295 6498.4667 0.503454 0.7295 6479 0.503454 0.7295 6468.3667 0.503454 0.7295 6459.8 0.503454 0.7295 6385.8667 0.503454 0.7295 6338.2667 0.503454 0.7295 6331.1333 0.503454 0.7295 6142.7667 0.503454 0.7295 6131.4867 0.503454 0.7295 6129.8667 0.503454 0.7295 6112.6667 0.503454 0.7295 6063.87 0.503454 0.7295 6052.7667 0.503454 0.7295 6046.8333 0.503454 0.7295 5975.4867 0.503454 0.7295 5843.0333 0.503454 0.7295 5736.3333 0.503454 0.7295 5716.7667 0.503454 0.7295 Draft 5644.4667 0.503454 0.7295 5604.7333 0.503454 0.7295 5579.6333 0.503454 0.7295 5553.1 0.503454 0.7295 5530.0667 0.503454 0.7295 5527.3867 0.503454 0.7295 5509.04 0.503454 0.7295 5412.7667 0.503454 0.7295 5382.8333 0.503454 0.7295 5312.6667 0.503454 0.7295 5308.2833 0.503454 0.7295 5303.9333 0.503454 0.7295 5269.5 0.503454 0.7295 5231.5333 0.503454 0.7295 5212.98184 0.503454 0.7295 5158.9 0.503454 0.7295 5149.6667 0.503454 0.7295 5134.5667 0.503454 0.7295 5130.1 0.503454 0.7295 5093.4333 0.503454 0.7295 5087.0333 0.503454 0.7295 5072.4667 0.503454 0.7295 5025.1333 0.503454 0.7295 5023.2733 0.503454 0.7295 5019.1333 0.503454 0.7295 4996.2333 0.503454 0.7295 4992.51 0.503454 0.7295

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4927.1567 0.503454 0.7295 4900.2333 0.503454 0.7295 4869.2333 0.503454 0.7295 4781.0667 0.503454 0.7295 4780.2533 0.503454 0.7295 4776.7967 0.503454 0.7295 4770.6 0.503454 0.7295 4764.2667 0.503454 0.7295 4755.5333 0.503454 0.7295 4735.6333 0.503454 0.7295 4614.2333 0.503454 0.7295 4600.3333 0.503454 0.7295 4560.3 0.503454 0.7295 4551.8333 0.503454 0.7295 4491.3333 0.503454 0.7295 4487.2667 0.503454 0.7295 4479.9533 0.503454 0.7295 4454.4667 0.503454 0.7295 4447.3333 0.503454 0.7295 4425.6333 0.503454 0.7295 4410.5 0.503454 0.7295 4406.7733 0.503454 0.7295 4405.0667 0.503454 0.7295 Draft 4392.1333 0.503454 0.7295 4365.2 0.503454 0.7295 4364.769 0.503454 0.7295 4362.9 0.503454 0.7295 4331.7067 0.503454 0.7295 4271.7 0.503454 0.7295 4267.7333 0.503454 0.7295 4260.2667 0.503454 0.7295 4254.9667 0.503454 0.7295 4245.6 0.503454 0.7295 4195.4 0.503454 0.7295 4160.9667 0.503454 0.7295 4158.5333 0.503454 0.7295 4153.3667 0.503454 0.7295 4114.13 0.503454 0.7295 4096.6667 0.503454 0.7295 4095.6667 0.503454 0.7295 4063 0.503454 0.7295 4056.7333 0.503454 0.7295 4050.8 0.503454 0.7295 4046.0667 0.503454 0.7295 4035.2667 0.503454 0.7295 3956.4333 0.503454 0.7295 3945.9667 0.503454 0.7295 3919.8 0.503454 0.7295 3908.2667 0.503454 0.7295 3889.4667 0.503454 0.7295

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3814.6 0.503454 0.7295 3785.26 0.503454 0.7295 3770.6333 0.503454 0.7295 3751.8767 0.503454 0.7295 3750 0.503454 0.7295 3743.3333 0.503454 0.7295 3733.7667 0.503454 0.7295 3711.7667 0.503454 0.7295 3684.5 0.503454 0.7295 3662.1767 0.503454 0.7295 3637.48 0.503454 0.7295 3630.8333 0.503454 0.7295 3627.6 0.503454 0.7295 3621.1 0.503454 0.7295 3593.4333 0.503454 0.7295 3585.7 0.503454 0.7295 3561.8667 0.503454 0.7295 3561.1 0.503454 0.7295 3531.5 0.503454 0.7295 3527.2667 0.503454 0.7295 3526.7 0.503454 0.7295 3498.6 0.503454 0.7295 3476.6967 0.503454 0.7295 Draft 3464.3667 0.503454 0.7295

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Supplemental Table S2. The differentially expressed genes in the two groups Gene_id Gene_nameDescriptionlocus Group B_FPKM Group F_FPKM ENSOCUG00000021179- GL019111:80214-8028819868.53333 1.00E-05 ENSOCUG00000026797- AAGW02083711:133-2287202.266667 1.00E-05 ENSOCUG000000233075S_rRNA 5S ribosomal11:83840343-83840462 RNA [Source:RFAM;Acc:RF00001]2910.753333 1.00E-05 ENSOCUG00000025865- AAGW02083842:241-3361800.563333 1.00E-05 ENSOCUG00000018677- 13:30980736-309808271310.606667 1.00E-05 ENSOCUG00000028924U6 U6 spliceosomal1:25144500-25144607 RNA [Source:RFAM;Acc:RF00026]932.4266667 1.00E-05 ENSOCUG00000018974Y_RNA Y RNA [Source:RFAM;Acc:RF00019]7:3031346-3031448 821.8 1.00E-05 ENSOCUG00000025175U6 U6 spliceosomal1:19069983-19070090 RNA [Source:RFAM;Acc:RF00026]465.9133333 1.00E-05 ENSOCUG000000255255S_rRNA 5S ribosomal9:43423230-43423349 RNA [Source:RFAM;Acc:RF00001]383.9833333 1.00E-05 ENSOCUG00000020172- GL018965:161694-164038290.7456667 1.00E-05 ENSOCUG000000206055S_rRNA 5S ribosomal1:91989026-91989137 RNA [Source:RFAM;Acc:RF00001]284.9963333 1.00E-05 ENSOCUG00000028838SNORA40 Small nucleolar4:48342276-48342388 RNA SNORA40 [Source:RFAM;Acc:RF00561]236.927 1.00E-05 ENSOCUG000000208145S_rRNA 5S ribosomal12:1470825-1677171 RNA [Source:RFAM;Acc:RF00001]220.8463333 1.00E-05 ENSOCUG000000193875S_rRNA 5S ribosomalX:102620910-102621024 RNA [Source:RFAM;Acc:RF00001]197.4093333 1.00E-05 ENSOCUG000000253225S_rRNA 5S ribosomal1:174562113-174562228 RNA [Source:RFAM;Acc:RF00001]188.5663333 1.00E-05 ENSOCUG00000019535snoU6-53 Small nucleolar17:41662993-41663102 RNA U6-53/MBII-28156.383 [Source:RFAM;Acc:RF00377] 1.00E-05 ENSOCUG00000018766SNORA66 Small nucleolar13:71706074-71714867 RNA SNORA66141.8548333 [Source:RFAM;Acc:RF00155] 1.00E-05 ENSOCUG00000026436- 7:62042932-62043049 130.35 1.00E-05 ENSOCUG000000243765S_rRNA 5S ribosomalDraft9:43411731-43411850 RNA [Source:RFAM;Acc:RF00001]127.9943333 1.00E-05 ENSOCUG000000244165S_rRNA 5S ribosomal9:43418889-43419008 RNA [Source:RFAM;Acc:RF00001]127.9943333 1.00E-05 ENSOCUG000000266115S_rRNA 5S ribosomal9:43420829-43420948 RNA [Source:RFAM;Acc:RF00001]127.9943333 1.00E-05 ENSOCUG00000018670SNORA65 Small nucleolarGL018699:202448-204725 RNA SNORA6597.40366667 [Source:RFAM;Acc:RF00302] 1.00E-05 ENSOCUG00000025836- UncharacterizedGL018720:54632-54746 protein [Source:UniProtKB/TrEMBL;Acc:G1TZK7]90.872 1.00E-05 ENSOCUG00000019359SNORA61 Small nucleolar13:136971306-136971435 RNA SNORA6189.42126667 [Source:RFAM;Acc:RF00420] 1.00E-05 ENSOCUG00000028757SNORA21 Small nucleolar19:40300583-40304272 RNA SNORA2186.63733333 [Source:RFAM;Acc:RF00412] 1.00E-05 ENSOCUG00000027907SNORA71 Small nucleolar4:1946654-1946787 RNA SNORA71 [Source:RFAM;Acc:RF00056]79.263 1.00E-05 ENSOCUG00000020979SNORA31 Small nucleolar3:140549024-140549152 RNA SNORA3176.19633333 [Source:RFAM;Acc:RF00322] 1.00E-05 ENSOCUG00000019923SNORA68 Small nucleolar13:118502766-118502896 RNA SNORA6875.71133333 [Source:RFAM;Acc:RF00263] 1.00E-05 ENSOCUG00000029045- Uncharacterized4:7839108-7839264 protein [Source:UniProtKB/TrEMBL;Acc:G1U9I4]34.023 1.00E-05 ENSOCUG00000019492SNORA48 Small nucleolar19:11601527-11606681 RNA SNORA48 [Source:RFAM;Acc:RF00554]33.0339 1.00E-05 ENSOCUG00000029018- Uncharacterized7:126851556-126877160 protein [Source:UniProtKB/TrEMBL;Acc:G1U9H2]32.45896667 1.00E-05 ENSOCUG00000019650SNORA42 Small nucleolar13:36920385-36942818 RNA SNORA42/SNORA8031.46656667 family [Source:RFAM;Acc:RF00406] 1.00E-05 ENSOCUG00000018902SNORA57 Small nucleolarGL018717:1669149-1674126 RNA SNORA57 [Source:RFAM;Acc:RF00191]26.7226 1.00E-05 ENSOCUG00000027978SNORD15 Small nucleolar1:141307966-141313359 RNA SNORD15 [Source:RFAM;Acc:RF00067]23.2878 1.00E-05 ENSOCUG00000018472U4 U4 spliceosomalGL018715:2136139-2136285 RNA [Source:RFAM;Acc:RF00015]18.26726667 1.00E-05 ENSOCUG00000028449SNORA18 Small nucleolar5:23506662-23528006 RNA SNORA1812.68623333 [Source:RFAM;Acc:RF00425] 1.00E-05 ENSOCUG00000027788U2 U2 spliceosomal19:43900697-43900888 RNA [Source:RFAM;Acc:RF00004]11.6302 1.00E-05 ENSOCUG00000019885SNORA25 Small nucleolar1:123190349-123190481 RNA SNORA25 [Source:RFAM;Acc:RF00402]11.3631 1.00E-05 ENSOCUG00000023289- UncharacterizedAAGW02082108:1469-15118 protein [Source:UniProtKB/TrEMBL;Acc:G1TSJ8]10.74416667 1.00E-05 ENSOCUG00000022460snoU109 Small nucleolar16:77764421-77804390 RNA U109 [Source:RFAM;Acc:RF01233]9.1159 1.00E-05 ENSOCUG00000022414U2 U2 spliceosomal19:43893909-43894100 RNA [Source:RFAM;Acc:RF00004]8.722633333 1.00E-05 ENSOCUG00000025425U3 Small nucleolar15:19264275-19264468 RNA U3 [Source:RFAM;Acc:RF00012]6.590666667 1.00E-05 ENSOCUG00000027893SNORA2 Small nucleolar4:32988908-33010949 RNA SNORA2/SNORA346.342533333 family [Source:RFAM;Acc:RF00410] 1.00E-05 ENSOCUG00000026960U2 U2 spliceosomal19:43849320-43849498 RNA [Source:RFAM;Acc:RF00004]4.54 1.00E-05 ENSOCUG00000020237U2 U2 spliceosomal3:21748884-21800779 RNA [Source:RFAM;Acc:RF00004]4.0715 1.00E-05

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ENSOCUG00000010964- 14:41065075-410658718.707646667 0.671497333 ENSOCUG00000025833- 14:28633590-286345918.83117 0.96739 ENSOCUG00000010829MYL4 myosin, light19:46660457-46674214 chain 4, alkali; 9.982684867atrial, embryonic [Source:HGNC 1.478484333 Symbol;Acc:HGNC:7585] ENSOCUG00000027420- 14:117265266-117266022145.3351517 22.02369667 ENSOCUG00000017655- Uncharacterized14:118855624-118892889 protein [Source:UniProtKB/TrEMBL;Acc:G1TE52]5.00421 0.764393333 ENSOCUG00000006901ANKRD1 Oryctolagus18:38907913-38917583 cuniculus ankyrin5.282653733 repeat domain 1 (cardiac 0.817438 muscle) (ANKRD1), mRNA. [Source:RefSeq mRNA;Acc:NM_001082054] ENSOCUG00000013346MYOZ3 myozenin 33:32361211-32374627 [Source:HGNC Symbol;Acc:HGNC:18565]15.44709667 2.404926667 ENSOCUG00000001849SMPX small muscleX:7489491-7510947 protein, X-linked161.2807033 [Source:HGNC Symbol;Acc:HGNC:11122] 25.22266667 ENSOCUG00000022110TCEAL7 transcriptionX:86741115-86741418 elongation factor23.21665667 A (SII)-like 7 [Source:HGNC 4.121073333 Symbol;Acc:HGNC:28336] ENSOCUG00000015238- Uncharacterized12:151335602-151335722 protein [Source:UniProtKB/TrEMBL;Acc:G1T904]390.928 76.18466667 ENSOCUG00000011736CA3 carbonic anhydrase3:101075704-101087678 III, muscle247.744492 specific [Source:HGNC 52.50103333 Symbol;Acc:HGNC:1374] ENSOCUG00000018543SNORA73 Small nucleolar13:137019939-137020142 RNA SNORA7328.32506667 family [Source:RFAM;Acc:RF00045] 6.018966667 ENSOCUG00000025586MYL2 myosin, light21:7092629-7124431 chain 2, regulatory,113.8373713 cardiac, slow [Source:HGNC 24.94596667 Symbol;Acc:HGNC:7583] ENSOCUG00000012392MYL3 myosin, light9:14874048-14878560 chain 3, alkali; 472.3030067ventricular, skeletal, 105.6394333 slow [Source:HGNC Symbol;Acc:HGNC:7584] ENSOCUG00000016660SFRP2 secreted frizzled-related15:10007154-10014824 protein27.07488333 2 [Source:HGNC 6.087516667 Symbol;Acc:HGNC:10777] ENSOCUG00000018609SNORA21 Small nucleolar19:40300583-40304272 RNA SNORA21161.2493333 [Source:RFAM;Acc:RF00412] 36.91033333 ENSOCUG00000015658- long intergenic2:95663805-95663976 non-protein coding75.92373333 RNA 116 [Source:HGNC 17.3856 Symbol;Acc:HGNC:27339] ENSOCUG00000005860MSS51 MSS51 mitochondrial18:14015189-14018897 translational9.628735667 activator [Source:HGNC 2.210953333 Symbol;Acc:HGNC:21000] ENSOCUG00000017368MYL6B myosin, light4:39721656-39724088 chain 6B, alkali,385.2902733 smooth muscle and 89.13616667 non-muscle [Source:HGNC Symbol;Acc:HGNC:29823] ENSOCUG00000017913YIPF7 Yip1 domain2:33395158-33419576 family, member7.380269667 7 [Source:HGNC Symbol;Acc:HGNC:26825] 1.709933333 ENSOCUG00000011454HRASLS HRAS-likeDraft 14:89113003-89130236suppressor [Source:HGNC5.096299333 Symbol;Acc:HGNC:14922] 1.20116 ENSOCUG00000022189- 12:123469013-1234694827.413541 1.759053333 ENSOCUG00000017131LMOD2 leiomodin 27:20911360-20919980 (cardiac) [Source:HGNC57.57983 Symbol;Acc:HGNC:6648] 13.83980333 ENSOCUG00000010113- 12:83665582-836665758.796195667 2.15023 ENSOCUG00000007983TNNC1 Troponin C,9:19523634-19526183 slow skeletal and1134.514743 cardiac muscles [Source:UniProtKB/Swiss-Prot;Acc:P02591] 278.16 ENSOCUG00000006310PPM1J protein phosphatase,13:51443757-51448700 Mg2+/Mn2+6.870769 dependent, 1J 1.720686667[Source:HGNC Symbol;Acc:HGNC:20785] ENSOCUG00000006570ABRA actin-binding3:122078135-122090555 Rho activating protein16.476574 [Source:HGNC Symbol;Acc:HGNC:30655] 4.29863 ENSOCUG00000012444FBXO40 F-box protein14:97364821-97369337 40 [Source:HGNC6.006916667 Symbol;Acc:HGNC:29816] 1.567966667 ENSOCUG00000006986SCIN scinderin [Source:HGNC10:26480543-26590300 Symbol;Acc:HGNC:21695]19.3975 5.063686667 ENSOCUG00000025599- GL019111:94654-947466076.733333 1590.31 ENSOCUG00000003951ATP1B4 ATPase, Na+/K+X:94802839-94824009 transporting, beta6.7004863 4 polypeptide [Source:HGNC 1.75546 Symbol;Acc:HGNC:808] ENSOCUG00000008959MYOZ2 myozenin 215:94465176-94502456 [Source:HGNC Symbol;Acc:HGNC:1330]67.28834367 17.9381 ENSOCUG00000024073DUSP26 dual specificity2:74208924-74214620 phosphatase 26 (putative)34.95524 [Source:HGNC 9.320313333 Symbol;Acc:HGNC:28161] ENSOCUG00000023632SNORD97 Small nucleolar1:152586616-152597723 RNA SNORD97102.2928667 [Source:RFAM;Acc:RF01291] 27.31073333 ENSOCUG00000014521C10orf71 chromosome18:5535391-5539453 10 open reading8.236597133 frame 71 [Source:HGNC 2.1998Symbol;Acc:HGNC:26973] ENSOCUG00000009959CASQ1 Oryctolagus13:32889974-33007056 cuniculus calsequestrin290.723379 1 (fast-twitch, 78.09223333 skeletal muscle) (CASQ1), nuclear gene encoding mitochondrial protein, mRNA. [Source:RefSeq mRNA;Acc:NM_001082268] ENSOCUG00000008850CACNG1 Oryctolagus19:50421318-50431444 cuniculus calcium37.43841267 channel, voltage-dependent, 10.07795 gamma subunit 1 (CACNG1), mRNA. [Source:RefSeq mRNA;Acc:NM_001082393] ENSOCUG00000000788GADL1 glutamate decarboxylase-like14:17799318-179918065.457648667 1 [Source:HGNC Symbol;Acc:HGNC:27949] 1.478429 ENSOCUG00000012592ASB5 Oryctolagus2:53701628-53785936 cuniculus ankyrin21.45505133 repeat and SOCS 5.833863333box-containing 5 (ASB5), mRNA. [Source:RefSeq mRNA;Acc:NM_001163067] ENSOCUG00000011211RSMTCK creatine kinase11:1651959-1663592 S-type, mitochondrial10.59811633 precursor [Source:RefSeq 2.88749 peptide;Acc:NP_001156542] ENSOCUG00000010424TNNI1 troponin I type16:70101750-70112680 1 (skeletal, slow)269.5459833 [Source:HGNC 75.80913333Symbol;Acc:HGNC:11945] ENSOCUG00000023019FOSB FBJ murineGL019006:121962-124101 osteosarcoma viral118.3252667 oncogene homolog 33.51292333 B [Source:HGNC Symbol;Acc:HGNC:3797] ENSOCUG00000025317PTP4A3 protein tyrosineGL019882:9617-18306 phosphatase 79.93277333type IVA, member 3 22.80596667 [Source:HGNC Symbol;Acc:HGNC:9636] ENSOCUG00000007471- CytochromeGL018752:872696-873291 c oxidase subunit541.8979767 6A, mitochondrial [Source:UniProtKB/TrEMBL;Acc:G1ST47] 155.809 ENSOCUG00000026126MB Myoglobin 4:85924478-85930824 [Source:UniProtKB/Swiss-Prot;Acc:P02170]722.8693433 207.9653333 ENSOCUG00000001522SH3BGR SH3 domainGL018907:456067-484448 binding glutamate-rich81.57835633 protein [Source:HGNC 23.50546667 Symbol;Acc:HGNC:10822] ENSOCUG00000024729HSPB3 Uncharacterized11:70471698-70472154 protein [Source:UniProtKB/TrEMBL;Acc:G1TXV2]9.230223333 2.686916667

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ENSOCUG00000025023- Oryctolagus9:10337708-10338971 cuniculus glyceraldehyde-3-phosphate129.5630733 38.06893333 dehydrogenase (GAPDH), mRNA. [Source:RefSeq mRNA;Acc:NM_001082253] ENSOCUG00000017871ACTN2 actinin, alpha16:26414334-26489882 2 [Source:HGNC349.8069467 Symbol;Acc:HGNC:164] 103.1885 ENSOCUG00000023172SOCS3 GL019170:17309-12763963.70896667 18.82820667 ENSOCUG00000011023NRAP nebulin-related18:61158733-61260552 anchoring protein66.20849267 [Source:HGNC 19.83893333 Symbol;Acc:HGNC:7988] ENSOCUG00000021287HSPB6 heat shock protein,GL018786:578411-584738 alpha-crystallin-related,166.8031333 B6 [Source:HGNC 50.32816667 Symbol;Acc:HGNC:26511] ENSOCUG00000023462MYLPF myosin lightGL018752:1818107-1820655 chain, phosphorylatable,882.6428067 fast skeletal muscle 266.764 [Source:HGNC Symbol;Acc:HGNC:29824] ENSOCUG00000008066DHRS7C dehydrogenase/reductase19:9698222-9715531 (SDR family)43.4202 member 7C 13.16046667 [Source:HGNC Symbol;Acc:HGNC:32423] ENSOCUG00000012560MYOZ1 myozenin 118:13783738-13787953 [Source:HGNC Symbol;Acc:HGNC:13752]608.1104533 184.6756667 ENSOCUG00000016643ITGB1BP2integrin betaX:49759476-49762741 1 binding protein13.78375167 (melusin) 2 [Source:HGNC 4.189813333 Symbol;Acc:HGNC:6154] ENSOCUG00000017035TRIM54 tripartite motif2:158777886-158800089 containing 5419.53343333 [Source:HGNC Symbol;Acc:HGNC:16008] 5.94522 ENSOCUG00000013131MYOM2 myomesin 2GL018865:488358-637412 [Source:HGNC 97.42797467Symbol;Acc:HGNC:7614] 30.12246667 ENSOCUG00000014182MYL1 myosin, light7:151162558-151172425 chain 1, alkali; 2490.106663skeletal, fast [Source:HGNC 774.4553333 Symbol;Acc:HGNC:7582] ENSOCUG00000010594CASQ2 Oryctolagus13:48463598-48534149 cuniculus calsequestrin33.72092 2 (cardiac muscle) 10.49121333 (CASQ2), nuclear gene encoding mitochondrial protein, mRNA. [Source:RefSeq mRNA;Acc:NM_001101691] ENSOCUG00000024802- UncharacterizedAAGW02081706:17230-19154 protein [Source:UniProtKB/TrEMBL;Acc:G1TS26]10.44519667 3.252936667 ENSOCUG00000003384PRKAG3 protein kinase,7:160092579-160099205 AMP-activated, gamma7.750675 3 non-catalytic 2.414053333 subunit [Source:HGNC Symbol;Acc:HGNC:9387] ENSOCUG00000021185FNDC5 fibronectin typeGL018704:5406019-5414173 III domain containing13.4252 5 [Source:HGNC 4.194873333 Symbol;Acc:HGNC:20240] ENSOCUG00000009100ANKRD23ankyrin repeat2:94641859-94645032 domain 23 [Source:HGNC117.0913633 Symbol;Acc:HGNC:24470] 37.1957 ENSOCUG00000016283RPL3L ribosomal proteinGL019283:77672-92352 L3-like [Source:HGNC48.516351 Symbol;Acc:HGNC:10351] 15.43159667 ENSOCUG00000017551XIRP2 xin actin-binding7:106756072-106812459 repeat containing52.36394767 2 [Source:HGNC Symbol;Acc:HGNC:14303] 16.6633 ENSOCUG00000016424AMPD1 AMP deaminase13:49496355-49520064 1 [Source:UniProtKB/Swiss-Prot;Acc:P81072]54.89815533 17.51773333 ENSOCUG00000011821TPM3 tropomyosinDraft13:38368885-38386777 3 [Source:HGNC Symbol;Acc:HGNC:12012]156.70029 50.0294 ENSOCUG00000000968DES desmin [Source:RefSeq7:160621567-160629173 peptide;Acc:NP_001164952]347.7070333 111.3746 ENSOCUG00000010198TPM2 Tropomyosin1:18090637-18256037 beta chain [Source:UniProtKB/Swiss-Prot;Acc:P58776]2453.236733 786.836 ENSOCUG00000015051PPP1R3C protein phosphatase18:39593993-39602191 1, regulatory22.45380133 subunit 3C [Source:HGNC 7.201983333 Symbol;Acc:HGNC:9293] ENSOCUG00000025140SRL OryctolagusGL018787:459178-500306 cuniculus sarcalumenin37.88071533 (SRL), mRNA. 12.16381667 [Source:RefSeq mRNA;Acc:NM_001082281] ENSOCUG00000014268SIX1 20:8229769-823425712.37461333 3.977326667 ENSOCUG00000013564TRIM63 tripartite motif13:139223047-139240154 containing 63, E3 ubiquitin42.3056 protein ligase 13.6724 [Source:HGNC Symbol;Acc:HGNC:16007] ENSOCUG00000007450- CytochromeGL018752:912386-912951 c oxidase subunit25.42336667 6A, mitochondrial 8.237803333 [Source:UniProtKB/TrEMBL;Acc:G1ST31] ENSOCUG00000011505- UncharacterizedGL019066:98903-112581 protein [Source:UniProtKB/TrEMBL;Acc:G1T1I5]23.91191767 7.78895 ENSOCUG00000025160TCAP titin-cap [Source:HGNC19:40892796-40932317 Symbol;Acc:HGNC:11610]438.9892 143.8236667 ENSOCUG00000027310SLC16A3 solute carrierGL019266:44943-47699 family 16 (monocarboxylate14.86857333 transporter), 4.886446667 member 3 [Source:HGNC Symbol;Acc:HGNC:10924] ENSOCUG00000014414MYOT myotilin [Source:HGNC3:20207681-20227140 Symbol;Acc:HGNC:12399]101.2987763 33.35463333 ENSOCUG00000026908- UncharacterizedGL019355:15204-30253 protein [Source:UniProtKB/TrEMBL;Acc:G1TSL2]218.263 71.8963 ENSOCUG00000027228SMTNL1 smoothelin-like1:190626869-190633253 1 [Source:HGNC28.70399833 Symbol;Acc:HGNC:32394] 9.634346667 ENSOCUG00000012459FHL3 four and a halfGL018704:511572-514985 LIM domains132.1617033 3 [Source:HGNC Symbol;Acc:HGNC:3704] 44.37636667 ENSOCUG00000021380SMCO1 single-pass 14:92257334-92262205membrane protein5.050987733 with coiled-coil domains 1.700833333 1 [Source:HGNC Symbol;Acc:HGNC:27407] ENSOCUG00000005950CAV3 caveolin 3 [Source:HGNCGL018703:239142-249827 Symbol;Acc:HGNC:1529]18.50879833 6.25213 ENSOCUG00000022163- Uncharacterized18:12327981-12405774 protein [Source:UniProtKB/TrEMBL;Acc:G1TLX3]7.071343333 2.401323333 ENSOCUG00000010229MYH8 myosin, heavy19:9145212-9173315 chain 8, skeletal126.5555113 muscle, perinatal 43.06603333[Source:HGNC Symbol;Acc:HGNC:7578] ENSOCUG00000029574CYP2F1 cytochromeGL018789:991445-1001435 P450, family 2, subfamily284.807 F, polypeptide 97.46661 [Source:HGNC Symbol;Acc:HGNC:2632] ENSOCUG00000007837LRRC39 leucine rich13:63974973-64004081 repeat containing22.90906933 39 [Source:HGNC 7.859933333Symbol;Acc:HGNC:28228] ENSOCUG00000009828ARPP21 cAMP-regulated14:22569928-22684866 phosphoprotein,5.7872511 21kDa [Source:HGNC 1.98956 Symbol;Acc:HGNC:16968] ENSOCUG00000008064TRDN triadin [Source:HGNC12:112385901-112811322 Symbol;Acc:HGNC:12261]43.2182435 14.8979 ENSOCUG00000013155HHATL hedgehog acyltransferase-like9:1440802-162106011.38994933 [Source:HGNC Symbol;Acc:HGNC:13242] 3.93124 ENSOCUG00000027853PGAM2 phosphoglycerate10:44639813-44641572 mutase 2 (muscle)542.7079167 [Source:HGNC 187.3336667 Symbol;Acc:HGNC:8889] ENSOCUG00000001526SYPL2 Oryctolagus13:54721148-54737335 cuniculus synaptophysin-like57.67747167 2 (SYPL2), 19.91823333 mRNA. [Source:RefSeq mRNA;Acc:NM_001081986] ENSOCUG00000006734MYO18B myosin XVIIIBGL018766:868171-1125158 [Source:HGNC12.30282047 Symbol;Acc:HGNC:18150] 4.260086667

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ENSOCUG00000022984- UncharacterizedGL018883:93392-94168 protein [Source:UniProtKB/TrEMBL;Acc:G1T3Y1]15.8602 5.49439 ENSOCUG00000008601ASB16 ankyrin repeat19:44491930-44500618 and SOCS box9.213305667 containing 16 [Source:HGNC 3.207606667 Symbol;Acc:HGNC:19768] ENSOCUG00000002173PYGM OryctolagusGL019294:57703-67956 cuniculus phosphorylase,530.706 glycogen, 186.0513333muscle (PYGM), mRNA. [Source:RefSeq mRNA;Acc:NM_001082184] ENSOCUG00000014862BIN1 bridging integrator7:58593560-58617815 1 [Source:HGNC28.75333333 Symbol;Acc:HGNC:1052] 10.08661333 ENSOCUG00000010649MKX mohawk homeobox16:6801733-6883139 [Source:HGNC5.42281 Symbol;Acc:HGNC:23729] 1.907096667 ENSOCUG00000007793ANKRD2 ankyrin repeat18:45754794-45789483 domain 2 (stretch 21.81358responsive muscle) 7.689566667 [Source:HGNC Symbol;Acc:HGNC:495] ENSOCUG00000008571MYOM1 myomesin 19:58833632-58987720 [Source:HGNC 75.98302667Symbol;Acc:HGNC:7613] 26.96463333 ENSOCUG00000023698ASB12 ankyrin repeatX:42881858-42891150 and SOCS box16.39346667 containing 12 [Source:HGNC 5.822266667 Symbol;Acc:HGNC:19763] ENSOCUG00000009244THBS4 thrombospondin11:747006-792130 4 [Source:HGNC37.10992 Symbol;Acc:HGNC:11788] 13.19623333 ENSOCUG00000002108- Uncharacterized19:12470445-12474664 protein [Source:UniProtKB/TrEMBL;Acc:G1U6X0]929.4095067 330.816 ENSOCUG00000023774FITM1 fat storage-inducing17:44179587-44180837 transmembrane44.532086 protein 1 [Source:HGNC 15.91446667 Symbol;Acc:HGNC:33714] ENSOCUG00000010852HSPB7 heat shock 27kDaGL018791:351350-353536 protein family,52.30673667 member 7 (cardiovascular) 18.79246667 [Source:HGNC Symbol;Acc:HGNC:5249] ENSOCUG00000015301SCN1B OryctolagusGL018786:11267-19657 cuniculus sodium54.51526333 channel, voltage-gated, 19.60946667 type I, beta (SCN1B), mRNA. [Source:RefSeq mRNA;Acc:NM_001082359] ENSOCUG00000001457MYF6 myogenic factor4:59978363-59980531 6 (herculin) 15.01316667[Source:HGNC Symbol;Acc:HGNC:7566] 5.404183333 ENSOCUG00000016259DDIT4L DNA-damage-inducible15:49644061-49648724 transcript57.75949667 4-like [Source:HGNC 20.79876667 Symbol;Acc:HGNC:30555] ENSOCUG00000016462IL1RL1 interleukin 12:90078069-90113742 receptor-like 1 [Source:HGNC7.72277 Symbol;Acc:HGNC:5998] 2.782473333 ENSOCUG00000028008APOBEC2 apolipoprotein12:30802522-30811693 B mRNA editing165.8807733 enzyme, catalytic 59.78406667 polypeptide-like 2 [Source:HGNC Symbol;Acc:HGNC:605] ENSOCUG00000004480CSRP3 cysteine and1:158112944-158133615 glycine-rich protein92.46186667 3 (cardiac LIM protein) 33.4775 [Source:HGNC Symbol;Acc:HGNC:2472] ENSOCUG00000011901EN1 engrailed homeobox7:64009345-64015371 1 [Source:HGNC7.304793333 Symbol;Acc:HGNC:3342] 2.647146667 ENSOCUG00000004509MYH3 myosin, heavy19:8926815-8951748 chain 3, skeletal 96.976193muscle, embryonic 35.21193333 [Source:HGNC Symbol;Acc:HGNC:7573] ENSOCUG00000008892RAPSN receptor-associatedDraft1:186748394-186760615 protein of the5.024189 synapse [Source:HGNC 1.828803333 Symbol;Acc:HGNC:9863] ENSOCUG00000001757TNNT3 troponin T typeAAGW02082683:20-4435 3 (skeletal, fast)597.7033333 [Source:HGNC Symbol;Acc:HGNC:11950] 217.904 ENSOCUG00000021115PKIA cAMP-dependent3:94362874-94376534 protein kinase29.71504333 inhibitor alpha [Source:UniProtKB/Swiss-Prot;Acc:P61926] 10.84700333 ENSOCUG00000017445PFKM phosphofructokinase,GL018949:202926-219365 muscle188.4263667 [Source:HGNC Symbol;Acc:HGNC:8877] 69.0504 ENSOCUG00000022132KCNA7 potassium voltage-gatedGL019028:38847-40843 channel,8.081243667 shaker-related subfamily, 2.966013333 member 7 [Source:HGNC Symbol;Acc:HGNC:6226] ENSOCUG00000012980KLHL41 kelch-like family7:109227204-109271867 member 4190.76475333 [Source:HGNC Symbol;Acc:HGNC:16905] 33.50716667 ENSOCUG00000021153MAP3K7CLMAP3K7 C-terminal14:158427451-158554682 like [Source:HGNC14.54108667 Symbol;Acc:HGNC:16457] 5.374206667 ENSOCUG00000012976HSPB2-C11orf52Uncharacterized1:104460633-104461649 protein [Source:UniProtKB/TrEMBL;Acc:G1T4G1]9.561723333 3.534753333 ENSOCUG00000021070ACA64 Small nucleolarGL018779:514365-587351 RNA ACA64172.5043333 [Source:RFAM;Acc:RF01225] 63.77166667 ENSOCUG00000022885- UncharacterizedGL018757:1239538-1239801 protein [Source:UniProtKB/TrEMBL;Acc:G1TPV7]95.3722 35.34893333 ENSOCUG00000026736SGCA sarcoglycan,19:37474893-37598932 alpha (50kDa dystrophin-associated20.9226 7.755636667glycoprotein) [Source:HGNC Symbol;Acc:HGNC:10805] ENSOCUG00000023342RTN2 reticulon 2 [Source:HGNCGL019006:124484-233041 Symbol;Acc:HGNC:10468]29.27852333 10.85697 ENSOCUG00000013394KERA keratocan [Source:HGNC4:70260812-70270171 Symbol;Acc:HGNC:6309]16.01538333 5.94413 ENSOCUG00000005171AK1 adenylate kinaseGL018847:478107-693595 1 [Source:HGNC178.7841 Symbol;Acc:HGNC:361] 66.37896667 ENSOCUG00000006329ALDOA Oryctolagus6:18443744-18448735 cuniculus aldolase3549.770667 A, fructose-bisphosphate 1321.590333 (ALDOA), mRNA. [Source:RefSeq mRNA;Acc:NM_001082238] ENSOCUG00000028843SNORA48 Small nucleolar19:11601527-11606681 RNA SNORA48106.6229 [Source:RFAM;Acc:RF00554] 39.74506667 ENSOCUG00000027154CKM creatine kinase,GL019006:25518-33118 muscle [Source:HGNC1146.6364 Symbol;Acc:HGNC:1994] 429.3466667 ENSOCUG00000025341ADSSL1 adenylosuccinateAAGW02083270:47-4782 synthase like 65.3272041 [Source:HGNC 24.53756667Symbol;Acc:HGNC:20093] ENSOCUG00000025110- 20:11576206-118924918.317223333 3.124563333 ENSOCUG00000017722GMPR guanosine monophosphateGL018711:3712208-3753018 reductase17.74819 [Source:HGNC Symbol;Acc:HGNC:4376] 6.71151 ENSOCUG00000013760NEURL neuralized E318:51420297-51490128 ubiquitin protein19.90326933 ligase 1 [Source:HGNC 7.535283333 Symbol;Acc:HGNC:7761] ENSOCUG00000013251STAC3 SH3 and cysteineGL018714:411602-417304 rich domain45.82181267 3 [Source:HGNC Symbol;Acc:HGNC:28423] 17.35881667 ENSOCUG00000022445MYH2 myosin, heavy19:9027577-9051481 chain 2, skeletal381.391699 muscle, adult [Source:HGNC 145.0050333 Symbol;Acc:HGNC:7572] ENSOCUG00000005808PDLIM3 PDZ and LIM2:62938283-62974046 domain 3 [Source:HGNC73.09453667 Symbol;Acc:HGNC:20767] 27.83003333 ENSOCUG00000026890- UncharacterizedGL019066:87421-89214 protein [Source:UniProtKB/TrEMBL;Acc:G1U179]22.93158333 8.78758 ENSOCUG000000193827SK 7SK RNA [Source:RFAM;Acc:RF00100]12:27003444-270037585.102123333 1.958256667 ENSOCUG00000009072DUSP13 dual specificity18:12327981-12405774 phosphatase 1313.24886667 [Source:HGNC Symbol;Acc:HGNC:19681] 5.103263333

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ENSOCUG00000016537SRPK3 SRSF proteinGL018816:638128-642733 kinase 3 [Source:HGNC9.81983 Symbol;Acc:HGNC:11402] 3.81888 ENSOCUG00000012693LDB3 LIM domain18:8393772-8454652 binding 3 [Source:HGNC54.465601 Symbol;Acc:HGNC:15710] 21.1908 ENSOCUG00000002752S100A1 S100 calcium13:38831299-38833955 binding protein18.32079433 A1 [Source:HGNC Symbol;Acc:HGNC:10486] 7.16315 ENSOCUG00000021799- 13:107997082-10799809671.88773333 28.21923333 ENSOCUG00000017004TMEM182 transmembrane2:89613620-89697493 protein 182 [Source:HGNC10.357889 Symbol;Acc:HGNC:26391] 4.069976667 ENSOCUG00000009276MYBPC1 myosin binding4:80935715-81149874 protein C, slow292.1764367 type [Source:HGNC 114.8120333 Symbol;Acc:HGNC:7549] ENSOCUG00000001264CMYA5 cardiomyopathy11:509806-560248 associated 522.84334077 [Source:HGNC Symbol;Acc:HGNC:14305] 8.979716667 ENSOCUG00000027792TMEM52 transmembraneAAGW02083280:4574-6863 protein 52 [Source:HGNC30.56981333 Symbol;Acc:HGNC:27916] 12.02886667 ENSOCUG00000007566ACTA1 actin, alpha GL018838:96908-986801, skeletal muscle3758.033867 [Source:HGNC Symbol;Acc:HGNC:129] 1490.837 ENSOCUG00000015430TRIM72 tripartite motifGL018752:993053-1184648 containing 72,10.12949133 E3 ubiquitin protein 4.023046667 ligase [Source:HGNC Symbol;Acc:HGNC:32671] ENSOCUG00000022842- 13:30514775-305348055476.833333 2176.9 ENSOCUG00000025973POPDC3 popeye domain12:93228455-93237601 containing 3 9.182574333[Source:HGNC Symbol;Acc:HGNC:17649] 3.65423 ENSOCUG00000024481CAPN3 calpain 3, (p94)17:29781689-29828844 [Source:HGNC40.15153533 Symbol;Acc:HGNC:1480] 15.99893333 ENSOCUG00000016243MT3 Oryctolagus5:12893441-12894623 cuniculus metallothionein65.00805 3 (MT3), 25.91333333mRNA. [Source:RefSeq mRNA;Acc:NM_001082220] ENSOCUG00000012404MG33A OryctolagusGL018776:1121774-1129325 cuniculus Mitsugumin33A119.2813567 (MG33A), mRNA. 47.5556 [Source:RefSeq mRNA;Acc:NM_001099969] ENSOCUG00000004821MLLT11 AF1q; Uncharacterized13:41110912-41115169 protein10.28124333 [Source:UniProtKB/TrEMBL;Acc:E2J6N2] 4.102956667 ENSOCUG00000001205RBFOX1 RNA binding6:1578018-1683512 protein, fox-1 homolog11.25862667 (C. elegans) 4.542426667 1 [Source:HGNC Symbol;Acc:HGNC:18222] ENSOCUG00000013367COL11A1 collagen, type13:61053456-61262810 XI, alpha 1 [Source:HGNC14.52371667 Symbol;Acc:HGNC:2186] 5.871773333 ENSOCUG00000008188LMOD3 leiomodin 39:36532519-36549716 (fetal) [Source:HGNC33.1275461 Symbol;Acc:HGNC:6649] 13.46701333 ENSOCUG00000011037MYH7 myosin, heavy17:43605972-43624939 chain 7, cardiac126.0784917 muscle, beta [Source:HGNC 51.35136667 Symbol;Acc:HGNC:7577] ENSOCUG00000020919TMOD4 OryctolagusDraft13:41018887-41022208 cuniculus tropomodulin39.23698033 4 (muscle) (TMOD4), 16.00943333 mRNA. [Source:RefSeq mRNA;Acc:NM_001171299] ENSOCUG00000025995ASB2 ankyrin repeat20:12328132-12353108 and SOCS box containing17.63076 2 [Source:HGNC 7.22492 Symbol;Acc:HGNC:16012] ENSOCUG00000023317- actinin, alpha1:194167912-194180541 3 (gene/pseudogene)157.2613407 [Source:HGNC 64.70706667 Symbol;Acc:HGNC:165] ENSOCUG00000017433- hemicentin GL019049:159035-1671942 [Source:HGNC7.854743333 Symbol;Acc:HGNC:21293] 3.240853333 ENSOCUG00000005702PTPLA protein tyrosine16:43706027-43724302 phosphatase-like15.53638 (proline instead 6.411506667 of catalytic arginine), member A [Source:HGNC Symbol;Acc:HGNC:9639] ENSOCUG00000014122- tropomyosin17:9208775-9235994 1 (alpha) [Source:HGNC480.0403333 Symbol;Acc:HGNC:12010] 198.6743333 ENSOCUG00000026636MHC Oryctolagus19:9056196-9080806 cuniculus myosin heavy368.27513 chain (MHC), 152.5336667 mRNA. [Source:RefSeq mRNA;Acc:NM_001109816] ENSOCUG00000017458NEB nebulin [Source:HGNC7:90491559-90705993 Symbol;Acc:HGNC:7720]70.52658067 29.45853333 ENSOCUG00000017328MYLK2 myosin light4:7410542-7596500 chain kinase 2 [Source:HGNC16.3351523 Symbol;Acc:HGNC:16243] 6.824063333 ENSOCUG00000013103COX7A1 cytochromeGL018786:882134-882875 c oxidase subunit VIIa307.77753 polypeptide 1 129.5753333 (muscle) [Source:HGNC Symbol;Acc:HGNC:2287] ENSOCUG00000006209HFE2 hemochromatosis13:42703582-42711688 type 2 (juvenile)17.5475 [Source:HGNC 7.391783333 Symbol;Acc:HGNC:4887] ENSOCUG00000024308MMP11 matrix metallopeptidaseGL019236:34356-42550 11 (stromelysin261.5936667 3) [Source:HGNC 110.6312 Symbol;Acc:HGNC:7157] ENSOCUG00000011182- UncharacterizedGL018951:94270-125977 protein [Source:UniProtKB/TrEMBL;Acc:G1T0S9]8.40492 3.55593 ENSOCUG00000009223DOK5 docking proteinGL018712:1875727-2034597 5 [Source:HGNC 6.31928Symbol;Acc:HGNC:16173] 2.677046667 ENSOCUG00000022868- Uncharacterized13:60449384-60454600 protein [Source:UniProtKB/TrEMBL;Acc:G1TSP2]69.00503333 29.31376667 ENSOCUG00000006084CMBL carboxymethylenebutenolidase11:35268802-3529550947.49233667 homolog (Pseudomonas) 20.18073333 [Source:HGNC Symbol;Acc:HGNC:25090] ENSOCUG00000018756SNORA4 Small nucleolar14:78838990-78845089 RNA SNORA4151.7151333 [Source:RFAM;Acc:RF00394] 64.7683 ENSOCUG00000021402- UncharacterizedGL018699:8523155-8523368 protein [Source:UniProtKB/TrEMBL;Acc:G1U3J0]30.94377667 13.22816667 ENSOCUG00000011179TNMD tenomodulinX:88777678-88794237 [Source:HGNC 8.644693333Symbol;Acc:HGNC:17757] 3.708096667 ENSOCUG00000027082- Uncharacterized17:36007914-36008469 protein [Source:UniProtKB/TrEMBL;Acc:G1TRV3]36.45373333 15.64243333 ENSOCUG00000024272NEXN nexilin (F actin13:87528989-87585006 binding protein)46.00752333 [Source:HGNC Symbol;Acc:HGNC:29557] 19.8325 ENSOCUG00000005991ALPK3 alpha-kinaseGL018738:517432-526791 3 [Source:HGNC Symbol;Acc:HGNC:17574]26.08434 11.32364 ENSOCUG00000008657CGREF1 cell growth 2:158854797-158961071regulator with EF-hand27.01596667 domain 1 [Source:HGNC 11.77962 Symbol;Acc:HGNC:16962] ENSOCUG00000009681- Uncharacterized13:54464273-54470150 protein [Source:UniProtKB/TrEMBL;Acc:G1TNI4]15.02588767 6.577043333 ENSOCUG00000026398- Uncharacterized13:60473113-60482329 protein [Source:UniProtKB/TrEMBL;Acc:G1TSW8]21.77343333 9.543836667 ENSOCUG00000013151KLHL40 kelch-like family9:1440802-1621060 member 4013.07617633 [Source:HGNC Symbol;Acc:HGNC:30372] 5.746143333 ENSOCUG00000013865PLN Oryctolagus12:107443755-107612783 cuniculus phospholamban66.50786667 (PLN), mRNA. 29.34573333 [Source:RefSeq mRNA;Acc:NM_001082621]

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ENSOCUG00000010371FRZB frizzled-related7:122923640-122969548 protein [Source:HGNC20.03972667 Symbol;Acc:HGNC:3959] 8.850653333 ENSOCUG00000004685ENY2 enhancer of11:74834913-74835219 yellow 2 homolog153.5949333 (Drosophila) [Source:HGNC 68.15573333 Symbol;Acc:HGNC:24449] ENSOCUG00000002688ATP2A1 ATPase, Ca++6:18725418-18741093 transporting, cardiac566.39853 muscle, fast twitch 252.074 1 [Source:HGNC Symbol;Acc:HGNC:811] ENSOCUG00000003619CACNA1Svoltage-dependent16:70324666-70378642 L-type calcium25.48051497 channel subunit alpha-1S 11.36246 [Source:RefSeq peptide;Acc:NP_001095190] ENSOCUG00000013549MLF1 myeloid leukemia14:52997627-53052594 factor 1 [Source:HGNC85.26407 Symbol;Acc:HGNC:7125] 38.0387 ENSOCUG00000016777TTN titin [Source:HGNC7:118225490-118453579 Symbol;Acc:HGNC:12403]39.83853967 17.82053333 ENSOCUG00000019855SNORA40 Small nucleolar1:123186090-123186217 RNA SNORA40114.7503333 [Source:RFAM;Acc:RF00561] 51.33966667 ENSOCUG00000021107VAMP1 vesicle-associated8:32523676-32526070 membrane10.60414333 protein 1 (synaptobrevin 4.747433333 1) [Source:HGNC Symbol;Acc:HGNC:12642] ENSOCUG00000027846DNAJB5 DnaJ (Hsp40)1:18869864-18874900 homolog, subfamily10.19262667 B, member 5 [Source:HGNC 4.581296667 Symbol;Acc:HGNC:14887] ENSOCUG00000023161RYR1 ryanodine receptor5:2456216-2564863 1 (skeletal)45.50247733 [Source:HGNC Symbol;Acc:HGNC:10483] 20.52133333 ENSOCUG00000002594SLC25A4 Oryctolagus2:62603660-62669990 cuniculus solute11.72456667 carrier family 25 (mitochondrial 5.289 carrier; adenine nucleotide translocator), member 4 (SLC25A4), nuclear gene encoding mitochondrial protein, mRNA. [Source:RefSeq mRNA;Acc:NM_001082686] ENSOCUG00000022657GAPDH Glyceraldehyde-3-phosphate1:67461814-67462816 dehydrogenase2381.022 [Source:UniProtKB/TrEMBL;Acc:G1TJG6] 1075.959333 ENSOCUG00000004422BTG2 BTG family,16:68471082-68475713 member 2 [Source:HGNC89.52196667 Symbol;Acc:HGNC:1131] 40.4901 ENSOCUG00000004988LOXL4 lysyl oxidase-like18:46350106-46364856 4 [Source:HGNC10.92119 Symbol;Acc:HGNC:17171] 4.942613333 ENSOCUG00000009858KLHL30 kelch-like familyGL018969:197653-203883 member 3014.82710833 [Source:HGNC Symbol;Acc:HGNC:24770] 6.73078 ENSOCUG00000024395- UncharacterizedX:70708973-70710017 protein [Source:UniProtKB/TrEMBL;Acc:G1TGW5]7.04227 3.200146667 ENSOCUG00000003372ART3 ADP-ribosyltransferase15:74278842-74302431 3 [Source:HGNC54.64816667 Symbol;Acc:HGNC:725] 24.93093333 ENSOCUG00000012081CACNB1 calcium channel,19:40502578-40519903 voltage-dependent,29.92180333 beta 1 subunit [Source:HGNC 13.68057 Symbol;Acc:HGNC:1401] ENSOCUG00000009266CAND2 cullin-associated9:11163772-11233101 and neddylation-dissociated8.492666667 2 (putative) 3.88333 [Source:HGNC Symbol;Acc:HGNC:30689] ENSOCUG00000009702FMOD Fibromodulin16:68440371-68447684 [Source:UniProtKB/Swiss-Prot;Acc:O46378]34.73266667 16.04226667 ENSOCUG00000000303PPP1R3A OryctolagusDraft7:31525844-31565294 cuniculus protein11.94047327 phosphatase regulatory 5.541333333 subunit (RG1), mRNA. [Source:RefSeq mRNA;Acc:NM_001082303] ENSOCUG00000001833CAP2 CAP, adenylateGL018711:2492188-2756963 cyclase-associated20.12941 protein, 2 (yeast) 9.349483333 [Source:HGNC Symbol;Acc:HGNC:20039] ENSOCUG00000026762- AAGW02081404:27531-276895581.883333 2613.038333 ENSOCUG00000025533CHCHD10 coiled-coil-helix-coiled-coil-helixGL019236:29179-3086629.84431 domain containing 13.99956667 10 [Source:HGNC Symbol;Acc:HGNC:15559] ENSOCUG00000005294RRAGD Ras-related 12:76196984-76243516GTP binding D [Source:HGNC26.94454 Symbol;Acc:HGNC:19903] 12.67566667 ENSOCUG00000022352- 12:101719693-101720774111.6327 52.5875 ENSOCUG00000000286PGM1 phosphoglucomutase-113:102819366-102963646 [Source:RefSeq75.71373333 peptide;Acc:NP_001075785] 35.92543333 ENSOCUG00000024465COL8A1 Oryctolagus14:120912576-121077726 cuniculus collagen, type34.847 VIII, alpha 1 (COL8A1), 16.6083 mRNA. [Source:RefSeq mRNA;Acc:NM_001082666] ENSOCUG00000028162UBE2QL1 ubiquitin-conjugatingGL018756:275670-310972 enzyme20.71131333 E2Q family-like 1 9.923723333[Source:HGNC Symbol;Acc:HGNC:37269] ENSOCUG00000003928 6-Sep septin 6 [Source:HGNCX:68338513-68407181 Symbol;Acc:HGNC:15848]9.352086667 4.484603333 ENSOCUG00000024335TMEM238 transmembrane6:11629593-11629794 protein 238 [Source:HGNC10.48943333 Symbol;Acc:HGNC:40042] 5.0305 ENSOCUG00000022294MURC muscle-related1:12553800-12562329 coiled-coil protein18.32934667 [Source:HGNC Symbol;Acc:HGNC:33742] 8.79238 ENSOCUG00000026468BDKRB1 OryctolagusGL018779:498092-504301 cuniculus bradykinin8.793416667 receptor B1 (BDKRB1), 4.22182 mRNA. [Source:RefSeq mRNA;Acc:NM_001082347] ENSOCUG00000021265- 4:35443191-354435437.823883333 3.757103333 ENSOCUG00000016799CYB5R1 cytochrome16:68812260-68818274 b5 reductase 1 [Source:HGNC57.35706667 Symbol;Acc:HGNC:13397] 27.59983333 ENSOCUG00000006135- Uncharacterized2:104510693-104511080 protein [Source:UniProtKB/TrEMBL;Acc:G1U1Y5]21.70842333 10.50664667 ENSOCUG00000016222TXLNB taxilin beta 12:129681217-129727994[Source:HGNC Symbol;Acc:HGNC:21617]12.600005 6.098473333 ENSOCUG00000011876SLN Oryctolagus1:108820358-108824797 cuniculus sarcolipin511.03784 (SLN), mRNA. [Source:RefSeq 248.171 mRNA;Acc:NM_001082387] ENSOCUG00000012700CORO6 coronin 6 [Source:HGNC19:18578753-18585370 Symbol;Acc:HGNC:21356]23.56486333 11.44444333 ENSOCUG00000014350ADAMTS18ADAM metallopeptidase5:31919263-32078296 with11.84485667 thrombospondin type 1 5.77528motif, 18 [Source:HGNC Symbol;Acc:HGNC:17110] ENSOCUG00000016975CRYM crystallin, mu6:12137414-12156602 [Source:HGNC Symbol;Acc:HGNC:2418]33.9774 16.56660333 ENSOCUG00000003641LHX8 LIM homeobox13:90499079-90525148 8 [Source:HGNC8.910123333 Symbol;Acc:HGNC:28838] 4.35161 ENSOCUG00000026022DERL3 derlin 3 [Source:HGNCGL019236:51191-91972 Symbol;Acc:HGNC:14236]10.60679 5.188546667 ENSOCUG00000009444ALDH1A1 retinal dehydrogenase1:59416688-59478488 1 [Source:RefSeq101.3726 peptide;Acc:NP_001075482] 49.732 ENSOCUG00000002473OLFML2Aolfactomedin-likeGL018699:2500880-2532561 2A [Source:HGNC44.46506667 Symbol;Acc:HGNC:27270] 21.81606667 ENSOCUG00000003788SGCG Oryctolagus8:41421536-41544607 cuniculus sarcoglycan,15.62589333 gamma (35kDa 7.672526667 dystrophin-associated glycoprotein) (SGCG), mRNA. [Source:RefSeq mRNA;Acc:NM_001082362] ENSOCUG00000029113MT-ND6 NADH-ubiquinoneMT:11771-14103 oxidoreductase1548.816333 chain 6 [Source:UniProtKB/Swiss-Prot;Acc:O79438] 765.0503333

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ENSOCUG00000006728MYOM3 myomesin 313:129235977-129282140 [Source:HGNC 17.14396367Symbol;Acc:HGNC:26679] 8.479133333 ENSOCUG00000023599APOD apolipoprotein14:91226176-91251611 D precursor [Source:RefSeq362.1856667 peptide;Acc:NP_001075727] 179.1716667 ENSOCUG00000024524- 12:46445761-4680269931.62469667 15.68258 ENSOCUG00000024316- AAGW02081504:2200-35279.97123 4.952223333 ENSOCUG00000021586- OryctolagusGL018725:834809-835308 cuniculus troponin3012.174413 C type 2 (fast) (TNNC2), 1499.522 mRNA. [Source:RefSeq mRNA;Acc:NM_001082645] ENSOCUG00000019019- 12:96932700-970490731333.416667 2845.356667 ENSOCUG000000281475_8S_rRNA5.8S ribosomalGL019111:98306-98459 RNA [Source:RFAM;Acc:RF00002]2631.370333 6923.65 ENSOCUG00000000568HBB1 Oryctolagus1:146236497-146238305 cuniculus hemoglobin,989.0313333 beta (HBB2), 2837.970667 mRNA. [Source:RefSeq mRNA;Acc:NM_001082260] ENSOCUG00000012040KRTAP11-1keratin associated14:160985580-160986075 protein 11-1 [Source:HGNC462.043 Symbol;Acc:HGNC:18922] 1333.298 ENSOCUG00000014311- Uncharacterized4:36357980-36362643 protein [Source:UniProtKB/TrEMBL;Acc:G1T754]64.30313333 218.6652333 ENSOCUG00000005594- Uncharacterized14:160043159-160043663 protein [Source:UniProtKB/TrEMBL;Acc:G1TSA5]310.514 1154.621667 ENSOCUG00000017116- Uncharacterized14:159972459-159973038 protein [Source:UniProtKB/TrEMBL;Acc:G1TD14]171.5336667 645.004 ENSOCUG00000023455- GL018835:598087-59823929.2465 121.755 ENSOCUG00000016589KRTAP15-1keratin associated14:160047738-160048149 protein 15-175.49793333 [Source:HGNC Symbol;Acc:HGNC:18927] 341.6386667 ENSOCUG00000005599- Uncharacterized14:159993309-159993852 protein [Source:UniProtKB/TrEMBL;Acc:G1SPA0]70.15253333 351.2556667 ENSOCUG00000006582PLA2G2A phospholipase13:132962501-132966605 A2, group IIA16.03706667 (platelets, synovial fluid) 85.78023 [Source:HGNC Symbol;Acc:HGNC:9031] ENSOCUG00000027358- GL019111:93487-93574118756.1 646888.1 ENSOCUG00000027336- CEBPZ opposite2:149103183-149103906 strand [Source:HGNC135.991 Symbol;Acc:HGNC:49288] 754.4556667 ENSOCUG00000027177- GL019111:164897-16498442856.13333 301560.6667 ENSOCUG00000010359- Uncharacterized1:98671225-98671366 protein [Source:UniProtKB/TrEMBL;Acc:G1SZ45]7.212 52.0896 ENSOCUG00000019413SNORD22 Small nucleolarDraftGL018717:1509413-1509538 RNA SNORD22 [Source:RFAM;Acc:RF00099]60.762 461.4916667 ENSOCUG00000027160- GL019111:95464-95544102394.8667 793224.6667 ENSOCUG00000026447SNORA71 Small nucleolar4:1945782-1945915 RNA SNORA719.620366667 [Source:RFAM;Acc:RF00056] 258.5243333 ENSOCUG00000020113- 1:171395346-171395426841.3 48723.8 ENSOCUG00000019830SNORA12 Small nucleolar18:48181409-48212530 RNA SNORA121.00E-05 [Source:RFAM;Acc:RF00586] 18.94603333 ENSOCUG00000014954MRPL36 mitochondrialGL019196:87703-87856 ribosomal protein 1.00E-05L36 [Source:HGNC 19.49926667 Symbol;Acc:HGNC:14490] ENSOCUG00000019530SNORA5 Small nucleolar10:45302531-45312841 RNA SNORA5 [Source:RFAM;Acc:RF00392]1.00E-05 25.07086667 ENSOCUG00000019496SNORA29 Small nucleolar12:149628993-149636248 RNA SNORA291.00E-05 [Source:RFAM;Acc:RF00429] 29.07386667 ENSOCUG00000019045SNORA33 Small nucleolar12:123074999-123078772 RNA SNORA331.00E-05 [Source:RFAM;Acc:RF00438] 37.85066667 ENSOCUG00000018667U8 U8 small nucleolar19:11078155-11078290 RNA [Source:RFAM;Acc:RF00096]1.00E-05 38.106 ENSOCUG00000024092SNORA16 Small nucleolar13:136970520-136970655 RNA SNORA16B/SNORA16A1.00E-05 family [Source:RFAM;Acc:RF00190] 41.99 ENSOCUG00000021204SNORA71 Small nucleolar4:1948855-1948986 RNA SNORA711.00E-05 [Source:RFAM;Acc:RF00056] 44.927 ENSOCUG00000019843SNORA5 Small nucleolar10:45302531-45312841 RNA SNORA5 [Source:RFAM;Acc:RF00392]1.00E-05 48.72933333 ENSOCUG00000019868SNORA72 Small nucleolar3:113845451-113852062 RNA SNORA721.00E-05 [Source:RFAM;Acc:RF00139] 51.62033333 ENSOCUG00000023699SNORA28 Small nucleolarGL018751:516854-521770 RNA SNORA281.00E-05 [Source:RFAM;Acc:RF00400] 51.952 ENSOCUG00000028597SNORA9 Small nucleolar11:152336-302400 RNA SNORA9 [Source:RFAM;Acc:RF00411]1.00E-05 57.20033333 ENSOCUG00000018058SNORA44 Small nucleolar13:136971020-136971151 RNA SNORA441.00E-05 [Source:RFAM;Acc:RF00405] 57.22533333 ENSOCUG00000028334SCARNA15Small Cajal13:36920385-36942818 body specific RNA 151.00E-05 [Source:RFAM;Acc:RF00426] 59.11133333 ENSOCUG00000025177SNORA11 Small nucleolar1:104276206-104276335 RNA SNORA111.00E-05 [Source:RFAM;Acc:RF00614] 71.539 ENSOCUG00000023202SNORA51 Small nucleolar15:13004896-13005028 RNA SNORA511.00E-05 [Source:RFAM;Acc:RF00432] 71.67233333 ENSOCUG00000019857SNORA30 Small nucleolar1:151224916-151289591 RNA SNORA30/SNORA371.00E-05 family 74.05433333 [Source:RFAM;Acc:RF00415] ENSOCUG00000018158SNORA9 Small nucleolar10:45186071-45286653 RNA SNORA9 [Source:RFAM;Acc:RF00411]1.00E-05 86.67033333 ENSOCUG00000023501U5 U5 spliceosomalGL018739:2155553-2155670 RNA [Source:RFAM;Acc:RF00020]1.00E-05 120.285 ENSOCUG000000206135S_rRNA 5S ribosomalGL018802:453446-494138 RNA [Source:RFAM;Acc:RF00001]1.00E-05 186.7333333 ENSOCUG00000028172- 9:49804488-498223861.00E-05 213.9613333 ENSOCUG000000289225S_rRNA 5S ribosomalGL018717:1733147-1746551 RNA [Source:RFAM;Acc:RF00001]1.00E-05 251.4166667 ENSOCUG00000020092- 12:22748029-227523151.00E-05 417.1233333

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ENSOCUG00000020132- GL018715:2500647-25433651.00E-05 422.56 ENSOCUG00000019006U6 U6 spliceosomalX:106672176-106776888 RNA [Source:RFAM;Acc:RF00026]1.00E-05 582.57 ENSOCUG00000021914U6 U6 spliceosomalGL019106:243250-243357 RNA [Source:RFAM;Acc:RF00026]1.00E-05 582.57 ENSOCUG00000024616- 3:21027824-210279111.00E-05 11959.73333 ENSOCUG00000024819- GL019301:61171-612451.00E-05 19622.66667 ENSOCUG00000019646SNORD30 Small nucleolarGL018717:1509979-1510048 RNA SNORD301.00E-05 [Source:RFAM;Acc:RF00088] 31299.36667 ENSOCUG00000019971- 15:104571734-1046140991.00E-05 35535.33333 ENSOCUG00000029114- MT:14103-14171 1.00E-05 35831.33333 ENSOCUG00000026701- GL019111:162517-1625911.00E-05 37244.33333

Draft

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Supplemental Table S2. The differentially expressed genes in the two groups Fold_change-GroupP-value B/Group F FDR Expression patterns 1986853333 0 0 UP 720226666.7 0 0 UP 291075333.3 0 0 UP 180056333.3 0 0 UP 131060666.7 0 0 UP 93242666.67 0 0 UP 82180000 0 0 UP 46591333.33 4.58E-245 1.37E-242 UP 38398333.33 1.05E-201 2.55E-199 UP 29074566.67 1.47E-152 2.93E-150 UP 28499633.33 2.17E-149 4.18E-147 UP 23692700 4.84E-124 7.48E-122 UP 22084633.33 1.35E-115 1.93E-113 UP 19740933.33 1.85E-103 2.43E-101 UP 18856633.33 1.03E-98 1.29E-96 UP 15638300 7.68E-82 8.02E-80 UP 14185483.33 6.14E-74 5.94E-72 UP 13035000 3.80E-68 3.43E-66 UP 12799433.33 1.44E-66 1.26E-64Draft UP 12799433.33 1.44E-66 1.26E-64 UP 12799433.33 1.44E-66 1.26E-64 UP 9740366.667 8.63E-51 6.18E-49 UP 9087200 4.09E-47 2.81E-45 UP 8942126.667 1.37E-46 9.28E-45 UP 8663733.333 5.15E-45 3.39E-43 UP 7926300 2.42E-41 1.46E-39 UP 7619633.333 9.05E-40 5.35E-38 UP 7571133.333 3.02E-39 1.76E-37 UP 3402300 7.42E-18 2.17E-16 UP 3303390 2.44E-17 6.94E-16 UP 3245896.667 8.04E-17 2.22E-15 UP 3146656.667 2.64E-16 7.12E-15 UP 2672260 1.00E-13 2.26E-12 UP 2328780 3.47E-12 6.74E-11 UP 1826726.667 1.24E-09 1.84E-08 UP 1268623.333 1.32E-06 1.27E-05 UP 1163020 4.16E-06 3.64E-05 UP 1136310 4.16E-06 3.64E-05 UP 1074416.667 1.30E-05 0.0001025 UP 911590 4.06E-05 0.00028351 UP 872263.3333 0.000125517 0.00077951 UP 659066.6667 0.001162783 0.00529919 UP 634253.3333 0.001162783 0.00529919 UP 454000 0.010164013 0.03134778 UP 407150 0.010164013 0.03134778 UP

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12.96750745 0.000125517 0.00077951 UP 9.128862196 0.000125517 0.00077951 UP 6.751972033 0.000178519 0.0010539 UP 6.599035297 2.22E-53 1.64E-51 UP 6.546642656 0.003469471 0.01322092 UP 6.462451872 0.003469471 0.01322092 UP 6.423105071 1.22E-06 1.19E-05 UP 6.394276442 1.00E-58 7.91E-57 UP 5.633643178 4.36E-09 6.02E-08 UP 5.131321263 6.05E-130 1.01E-127 UP 4.718849826 1.72E-80 1.78E-78 UP 4.705968356 3.47E-10 5.57E-09 UP 4.563357789 1.75E-37 9.78E-36 UP 4.470896823 5.00E-149 9.52E-147 UP 4.447607261 9.50E-10 1.43E-08 UP 4.368677244 9.45E-52 6.85E-50 UP 4.367047058 1.02E-24 3.91E-23 UP 4.355015334 0.000567186 0.00287273 UP 4.322490945 6.27E-120 9.36E-118 UP 4.316115444 0.001418955 0.00624968 UP 4.242814723 0.010389537 0.03202624Draft UP 4.214506099 0.001418955 0.00624968 UP 4.160451462 4.68E-19 1.43E-17 UP 4.090816176 0.001494521 0.00654755 UP 4.078640865 0 0 UP 3.993039019 0.003887805 0.01443102 UP 3.832982601 5.10E-06 4.39E-05 UP 3.831023193 0.003887805 0.01443102 UP 3.830707008 8.13E-07 8.18E-06 UP 3.821099869 0 0 UP 3.81694046 0.003887805 0.01443102 UP 3.751141072 3.01E-21 1.01E-19 UP 3.750436144 3.15E-11 5.59E-10 UP 3.745518858 4.85E-31 2.29E-29 UP 3.744248174 0.001494521 0.00654755 UP 3.722820652 8.53E-85 9.18E-83 UP 3.714883748 5.23E-12 1.00E-10 UP 3.691518948 0.010389537 0.03202624 UP 3.677674657 1.15E-07 1.32E-06 UP 3.670356029 0.000211144 0.00121222 UP 3.555587189 2.02E-77 2.06E-75 UP 3.530735458 8.69E-35 4.65E-33 UP 3.504906172 8.16E-24 3.02E-22 UP 3.477963254 6.94E-152 1.37E-149 UP 3.475912701 5.04E-202 1.25E-199 UP 3.47061207 3.65E-24 1.37E-22 UP 3.43524734 0.000567186 0.00287273 UP

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3.403380709 6.01E-37 3.31E-35 UP 3.389979956 4.03E-97 4.88E-95 UP 3.383698075 4.74E-19 1.44E-17 UP 3.337301032 8.00E-20 2.54E-18 UP 3.314309746 1.43E-46 9.63E-45 UP 3.308702849 5.95E-240 1.75E-237 UP 3.299290298 4.28E-13 9.17E-12 UP 3.292856412 1.12E-165 2.49E-163 UP 3.289824767 8.97E-05 0.00057335 UP 3.285569471 8.13E-07 8.18E-06 UP 3.234395634 1.76E-27 7.45E-26 UP 3.215300555 0 0 UP 3.214205921 2.43E-10 3.96E-09 UP 3.211005236 0.000579179 0.00292834 UP 3.210647791 0.003849448 0.0143009 UP 3.20038269 8.97E-05 0.00057335 UP 3.147981173 1.85E-32 9.16E-31 UP 3.143961836 3.07E-14 7.22E-13 UP 3.142471639 1.99E-15 5.12E-14 UP 3.133861801 8.58E-16 2.25E-14 UP 3.132164088 1.86E-42 1.17E-40Draft UP 3.121959884 1.66E-92 1.91E-90 UP 3.11785014 0 0 UP 3.117724701 3.65E-07 3.89E-06 UP 3.114212945 4.34E-11 7.58E-10 UP 3.111289156 8.63E-05 0.00055427 UP 3.094233639 1.10E-12 2.28E-11 UP 3.086182765 5.93E-08 7.11E-07 UP 3.069979608 1.43E-07 1.62E-06 UP 3.052273733 5.60E-115 7.95E-113 UP 3.042819116 3.50E-05 0.00024865 UP 3.037022632 9.50E-28 4.06E-26 UP 3.035802955 3.59E-58 2.81E-56 UP 2.979340408 9.69E-09 1.29E-07 UP 2.978200182 2.09E-35 1.13E-33 UP 2.969713513 0.010389537 0.03202624 UP 2.960398829 5.71E-06 4.84E-05 UP 2.944769343 0.003849448 0.0143009 UP 2.938638679 1.99E-33 1.03E-31 UP 2.922098442 2.93E-73 2.82E-71 UP 2.914664585 3.65E-07 3.89E-06 UP 2.908809536 0.010389537 0.03202624 UP 2.900962115 1.20E-12 2.47E-11 UP 2.897291778 0.000225533 0.00128589 UP 2.897012194 2.29E-137 4.09E-135 UP 2.895712221 3.99E-16 1.07E-14 UP 2.887927273 0.000226111 0.00128876 UP

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2.886617077 3.57E-05 0.00025256 UP 2.872330252 0.00145729 0.006412 UP 2.852470824 5.31E-133 9.10E-131 UP 2.850642965 2.52E-08 3.19E-07 UP 2.843489842 0.010389537 0.03202624 UP 2.836776238 9.22E-07 9.16E-06 UP 2.817877245 2.46E-20 8.03E-19 UP 2.815650263 1.41E-05 0.00011054 UP 2.812160036 1.15E-10 1.93E-09 UP 2.809445452 5.35E-230 1.52E-227 UP 2.798214161 1.28E-12 2.62E-11 UP 2.783388556 1.51E-14 3.62E-13 UP 2.780048241 6.33E-15 1.57E-13 UP 2.778063908 3.57E-05 0.00025256 UP 2.777063544 1.07E-15 2.78E-14 UP 2.775505486 0.003849448 0.0143009 UP 2.774665267 3.98E-42 2.45E-40 UP 2.761910736 3.86E-24 1.44E-22 UP 2.759497018 0.003849448 0.0143009 UP 2.754071811 6.89E-25 2.67E-23 UP 2.747254945 0.010389537 0.03202624Draft UP 2.742966321 2.18E-146 4.11E-144 UP 2.739470287 1.01E-08 1.34E-07 UP 2.728823681 5.03E-47 3.44E-45 UP 2.724614747 0.001494521 0.00654755 UP 2.708816124 2.38E-23 8.62E-22 UP 2.705717806 8.88E-05 0.00057023 UP 2.705060985 0.00145729 0.006412 UP 2.705030969 3.23E-43 2.07E-41 UP 2.698022006 1.71E-24 6.50E-23 UP 2.697728233 2.31E-06 2.11E-05 UP 2.696749031 1.01E-08 1.34E-07 UP 2.694319157 1.41E-05 0.00011054 UP 2.693384802 2.46E-44 1.59E-42 UP 2.685984135 0 0 UP 2.68267005 3.57E-27 1.50E-25 UP 2.670654017 4.68E-274 1.45E-271 UP 2.662334244 3.30E-17 9.31E-16 UP 2.661883421 0.003581026 0.01360115 UP 2.64444067 1.43E-05 0.00011124 UP 2.641343192 5.70E-06 4.83E-05 UP 2.63968527 3.39E-12 6.58E-11 UP 2.630196279 2.12E-91 2.42E-89 UP 2.626462419 3.97E-19 1.22E-17 UP 2.609544759 9.32E-07 9.25E-06 UP 2.605441574 0.010389537 0.03202624 UP 2.596155794 0.000217275 0.00124495 UP

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2.571390041 0.00145729 0.006412 UP 2.570247513 4.05E-14 9.42E-13 UP 2.557644937 1.39E-05 0.00010876 UP 2.547472941 5.93E-18 1.74E-16 UP 2.544950462 0.001357199 0.00602207 UP 2.544824164 2.58E-69 2.36E-67 UP 2.543882131 9.32E-07 9.25E-06 UP 2.541371034 2.50E-08 3.17E-07 UP 2.520754359 0 0 UP 2.517865729 0.001357199 0.00602207 UP 2.515886505 0 0 UP 2.512861624 0.00145729 0.006412 UP 2.509638268 4.87E-11 8.43E-10 UP 2.508671855 8.28E-17 2.28E-15 UP 2.508250484 5.04E-29 2.25E-27 UP 2.505813286 0.001357199 0.00602207 UP 2.478548911 0.000559758 0.00283926 UP 2.473480471 8.88E-05 0.00057023 UP 2.459902971 4.21E-09 5.83E-08 UP 2.455212001 3.69E-30 1.72E-28 UP 2.450866281 2.85E-10 4.63E-09Draft UP 2.440270619 3.35E-05 0.00023884 UP 2.430358055 5.27E-37 2.92E-35 UP 2.423665167 0.008559301 0.02748972 UP 2.423202658 8.50E-05 0.00054656 UP 2.41621716 1.21E-108 1.67E-106 UP 2.414385873 1.20E-83 1.28E-81 UP 2.39409681 3.43E-17 9.68E-16 UP 2.393757429 3.51E-05 0.00024917 UP 2.375278706 2.97E-69 2.70E-67 UP 2.37391969 3.35E-05 0.00023884 UP 2.364555991 5.07E-59 4.03E-57 UP 2.36363483 0.003581026 0.01360115 UP 2.360541592 0.009648455 0.03055726 UP 2.354014553 8.19E-17 2.26E-15 UP 2.353350391 7.92E-12 1.49E-10 UP 2.342428832 9.86E-35 5.24E-33 UP 2.339233958 5.75E-08 6.92E-07 UP 2.331302042 0.003581026 0.01360115 UP 2.330438785 1.67E-09 2.45E-08 UP 2.319804529 8.12E-12 1.52E-10 UP 2.303529607 3.55E-07 3.80E-06 UP 2.293449761 1.49E-07 1.68E-06 UP 2.284596119 8.50E-05 0.00054656 UP 2.28141303 5.26E-06 4.49E-05 UP 2.275643953 0.000217275 0.00124495 UP 2.266355586 1.09E-15 2.83E-14 UP

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2.264208744 5.54E-06 4.70E-05 UP 2.253587861 6.29E-34 3.28E-32 UP 2.246953395 6.53E-121 9.84E-119 UP 2.242517463 8.39E-07 8.43E-06 UP 2.241508516 2.54E-19 7.89E-18 UP 2.23554138 6.55E-10 1.00E-08 UP 2.235120342 1.60E-25 6.32E-24 UP 2.233658187 0.001357199 0.00602207 UP 2.224834454 0.001357199 0.00602207 UP 2.21732558 4.40E-11 7.67E-10 UP 2.216783261 0.001227051 0.00553819 UP 2.212929362 0 0 UP 2.210959387 3.83E-20 1.24E-18 UP 2.209598296 0.001357199 0.00602207 UP 2.202881142 0.000202634 0.00117465 UP 2.200608514 0.008559301 0.02748972 UP 2.191982384 5.20E-13 1.11E-11 UP 2.187175193 1.35E-07 1.54E-06 UP 2.186954667 0.003581026 0.01360115 UP 2.165072267 3.29E-08 4.11E-07 UP 2.154801481 0.001227051 0.00553819Draft UP 2.152997046 1.24E-05 9.80E-05 UP 2.136165881 0 0 UP 2.131802412 1.35E-07 1.54E-06 UP 2.125690167 7.84E-07 7.90E-06 UP 2.122799144 3.40E-24 1.27E-22 UP 2.107524567 7.46E-17 2.07E-15 UP 2.098167784 3.29E-08 4.11E-07 UP 2.08705066 1.24E-05 9.80E-05 UP 2.085376559 0.003213511 0.01244257 UP 2.085167146 0.002819175 0.0110266 UP 2.084685451 3.12E-05 0.00022432 UP 2.082849735 0.007403752 0.02447249 UP 2.082424315 0.008559301 0.02748972 UP 2.078167139 5.27E-13 1.12E-11 UP 2.066160975 1.14E-05 9.12E-05 UP 2.066091678 0.001087138 0.00497934 UP 2.059216589 4.16E-102 5.41E-100 UP 2.059065928 7.89E-06 6.53E-05 UP 2.050957992 0.001227051 0.00553819 UP 2.050957539 6.47E-08 7.72E-07 UP 2.047546387 0.007403752 0.02447249 UP 2.044269943 0.002819175 0.0110266 UP 2.038377704 1.83E-21 6.17E-20 UP 2.038179812 2.88E-10 4.67E-09 UP 2.036603326 0.000184884 0.00108629 UP 2.024463314 3.84E-301 1.21E-298 UP

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2.02190047 7.26E-05 0.00047533 UP 2.021444983 6.68E-72 6.32E-70 UP 2.016549361 1.67E-07 1.88E-06 UP 2.013485525 0.003213511 0.01244257 UP 2.008756399 0 0 UP 0.468629006 0.000831341 0.0039454 DOWN 0.380055366 1.80E-05 0.00013694 DOWN 0.348499491 4.76E-07 4.94E-06 DOWN 0.346541433 0.000432797 0.00226012 DOWN 0.294071135 0.013403258 0.03892696 DOWN 0.268931381 6.92E-13 1.45E-11 DOWN 0.26594202 4.74E-08 5.78E-07 DOWN 0.240207794 0.007488757 0.02471575 DOWN 0.220987671 1.26E-07 1.44E-06 DOWN 0.199719293 1.80E-09 2.61E-08 DOWN 0.186955277 0.003319497 0.01283573 DOWN 0.183580591 0 0 DOWN 0.180250485 3.85E-23 1.38E-21 DOWN 0.142114467 0 0 DOWN 0.138453741 0.004505496 0.01637305 DOWN 0.131664349 2.81E-22 9.77E-21Draft DOWN 0.129086841 0 0 DOWN 0.037212616 2.05E-27 8.63E-26 DOWN 0.017266716 0 0 DOWN 5.28E-07 0.013008502 0.03836567 DOWN 5.13E-07 0.013921514 0.04035772 DOWN 3.99E-07 0.001292689 0.00574466 DOWN 3.44E-07 0.000512035 0.00261789 DOWN 2.64E-07 2.87E-05 0.00020795 DOWN 2.62E-07 3.05E-05 0.00022019 DOWN 2.38E-07 1.19E-05 9.50E-05 DOWN 2.23E-07 2.66E-06 2.40E-05 DOWN 2.05E-07 1.03E-06 1.01E-05 DOWN 1.94E-07 3.97E-07 4.19E-06 DOWN 1.92E-07 3.97E-07 4.19E-06 DOWN 1.75E-07 5.95E-08 7.13E-07 DOWN 1.75E-07 5.95E-08 7.13E-07 DOWN 1.69E-07 2.06E-08 2.63E-07 DOWN 1.40E-07 4.27E-10 6.75E-09 DOWN 1.40E-07 4.27E-10 6.75E-09 DOWN 1.35E-07 1.63E-10 2.70E-09 DOWN 1.15E-07 2.00E-12 4.03E-11 DOWN 8.31E-08 2.45E-17 6.96E-16 DOWN 5.36E-08 3.35E-27 1.41E-25 DOWN 4.67E-08 2.72E-31 1.30E-29 DOWN 3.98E-08 7.54E-37 4.14E-35 DOWN 2.40E-08 7.18E-62 5.87E-60 DOWN

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2.37E-08 8.96E-63 7.43E-61 DOWN 1.72E-08 5.60E-87 6.22E-85 DOWN 1.72E-08 5.60E-87 6.22E-85 DOWN 8.36E-10 0 0 DOWN 5.10E-10 0 0 DOWN 3.19E-10 0 0 DOWN 2.81E-10 0 0 DOWN 2.79E-10 0 0 DOWN 2.68E-10 0 0 DOWN

Draft

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Supplementary Table S3. The significant GO terms of differentially expressed genes GO_term Type Number Diff_geneof diff_gene cluster in this frequency P-valueGO in FDRall GO The significant GO terms of up-regulated genes titin binding molecular_function 7 3.27% 4.10E-11 6.51E-09 actin binding molecular_function 17 7.94% 2.99E-10 3.17E-08 structural constituentmolecular_function of muscle 7 3.27% 9.40E-10 8.94E-08 FATZ binding molecular_function 3 1.40% 1.55E-06 5.29E-05 tropomyosin bindingmolecular_function 4 1.87% 3.08E-06 0.000101 motor activity molecular_function 6 2.80% 3.48E-06 0.0001 cytochrome-c oxidasemolecular_function activity 5 2.34% 4.77E-06 0.00013 cytoskeletal proteinmolecular_function binding 6 2.80% 6.13E-06 0.000162 titin Z domain bindingmolecular_function 2 0.93% 3.65E-05 0.001087 G-protein coupled receptormolecular_function activity 2 0.93% 3.68E-05 0.000761 microfilament motormolecular_function activity 3 1.40% 4.15E-05 0.000841 actin filament bindingmolecular_function 6 2.80% 5.18E-05 0.001028 glyceraldehyde-3-phosphatemolecular_function dehydrogenase (NAD+) 2 (phosphorylating) 0.93% 7.24E-05activity 0.001813 telethonin bindingmolecular_function 2 0.93% 7.24E-05 0.001813 voltage-gated calciummolecular_function channel activity 4 1.87% 7.32E-05 0.001182 actin monomer bindingmolecular_function 3 1.40% 7.40E-05 0.001174 muscle alpha-actininmolecular_function binding 2 0.93% 0.000125 0.002597 troponin I bindingmolecular_functionDraft 2 0.93% 0.000125 0.002597 fructose binding molecular_function 2 0.93% 0.000125 0.002597 high voltage-gated molecular_functioncalcium channel activity 2 0.93% 0.000296 0.005311 cation binding molecular_function 2 0.93% 0.000418 0.007244 nucleic acid bindingmolecular_function 2 0.93% 0.000508 0.00499 poly(A) RNA bindingmolecular_function 1 0.47% 0.000547 0.00531 oxidoreductase activity,molecular_function acting on the aldehyde 3or oxo group of 1.40% donors, 0.000551NAD or NADP 0.009042 as acceptor intramolecular transferasemolecular_function activity, phosphotransfe 2rases 0.93% 0.00057 0.005321 creatine kinase activitymolecular_function 1 0.47% 0.0009 0.014048 phosphofructokinasemolecular_function activity 1 0.47% 0.0009 0.014048 interleukin-33 receptormolecular_function activity 1 0.47% 0.0009 0.014048 nickel cation bindingmolecular_function 1 0.47% 0.0009 0.014048 metalloenzyme activatormolecular_function activity 1 0.47% 0.0009 0.014048 ligase regulator activitymolecular_function 1 0.47% 0.0009 0.014048 cadmium ion bindingmolecular_function 1 0.47% 0.0009 0.014048 voltage-gated sodiummolecular_function channel activity involved 1 in Purkinje myocyte 0.47% action 0.0009 potential 0.014048 ATPase inhibitor activitymolecular_function 1 0.47% 0.0009 0.014048 interleukin-33 bindingmolecular_function 1 0.47% 0.0009 0.014048 troponin T binding molecular_function 1 0.47% 0.0009 0.014048 translation factor activity,molecular_function non-nucleic acid bindi 1ng 0.47% 0.0009 0.014048 NADP binding molecular_function 3 1.40% 0.000971 0.005108 calcium channel regulatormolecular_function activity 2 0.93% 0.001223 0.017919 protein tyrosine/serine/threoninemolecular_function phosphatase activ 4ity 1.87% 0.001385 0.007051 connexin binding molecular_function 1 0.47% 0.001786 0.024635 adenylosuccinate synthasemolecular_function activity 1 0.47% 0.001786 0.024635 bradykinin receptormolecular_function activity 1 0.47% 0.001786 0.024635 troponin C binding molecular_function 1 0.47% 0.001786 0.024635

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GMP reductase activitymolecular_function 1 0.47% 0.001786 0.024635 calcium-dependentmolecular_function ATPase activity 1 0.47% 0.001786 0.024635 phosphoserine phosphatasemolecular_function activity 1 0.47% 0.001786 0.024635 sodium channel regulatormolecular_function activity 2 0.93% 0.001848 0.025132 ATPase binding molecular_function 3 1.40% 0.002419 0.009477 calcium-dependentmolecular_function protein binding 3 1.40% 0.002669 0.010331 protein-lysine 6-oxidasemolecular_function activity 1 0.47% 0.002952 0.035123 glycogen phosphorylasemolecular_function activity 1 0.47% 0.002952 0.035123 sodium ion binding molecular_function 1 0.47% 0.002952 0.035123 actinin binding molecular_function 1 0.47% 0.002952 0.035123 6-phosphofructokinasemolecular_function activity 1 0.47% 0.002952 0.035123 thyroid hormone receptormolecular_function coactivator activity 1 0.47% 0.002952 0.035123 phosphoglycerate mutasemolecular_function activity 1 0.47% 0.002952 0.035123 AMP deaminase activitymolecular_function 1 0.47% 0.002952 0.035123 ryanodine-sensitivemolecular_function calcium-release channel activit 1y 0.47% 0.002952 0.035123 calcium channel activitymolecular_function 3 1.40% 0.003528 0.011911 actin-dependent ATPasemolecular_function activity 1 0.47% 0.004391 0.04918 aldehyde dehydrogenasemolecular_function (NAD) activity 1 0.47% 0.004391 0.04918 endopeptidase activatormolecular_function activity 1 0.47% 0.004391 0.04918 acetylcholine receptormolecular_function binding 1 0.47% 0.004391 0.04918 hydrolase activity, molecular_functionacting on carbon-nitrogen (butDraft 1 not peptide) 0.47%bonds, in 0.006097 cyclic amidines 0.063787 chitin binding molecular_function 1 0.47% 0.006097 0.063787 phosphorylase activitymolecular_function 1 0.47% 0.006097 0.063787 LIM domain bindingmolecular_function 1 0.47% 0.006097 0.063787 fructose-bisphosphatemolecular_function aldolase activity 1 0.47% 0.006097 0.063787 filamin binding molecular_function 1 0.47% 0.006097 0.063787 thyroid hormone bindingmolecular_function 1 0.47% 0.006097 0.063787 voltage-gated sodiummolecular_function channel activity involved 1 in cardiac muscle 0.47% cell action 0.006097 potential 0.063787 sodium channel inhibitormolecular_function activity 1 0.47% 0.006097 0.063787 phosphopyruvate hydratasemolecular_function activity 1 0.47% 0.006097 0.063787 tau protein binding molecular_function 1 0.47% 0.006097 0.063787 interleukin-1 receptormolecular_function activity 1 0.47% 0.006097 0.063787 enzyme inhibitor activitymolecular_function 2 0.93% 0.006207 0.016322 Wnt-protein bindingmolecular_function 2 0.93% 0.006989 0.018329 protein phosphatasemolecular_function 1 binding 1 0.47% 0.008063 0.081664 receptor agonist activitymolecular_function 1 0.47% 0.008063 0.081664 ion channel bindingmolecular_function 3 1.40% 0.010108 0.0248 cAMP-dependent proteinmolecular_function kinase inhibitor activity 1 0.47% 0.010283 0.10092 phosphogluconate dehydrogenasemolecular_function (decarboxylating) 1 activity 0.47% 0.010283 0.10092 peptide binding molecular_function 1 0.47% 0.010283 0.10092 oxidoreductase activity,molecular_function acting on the CH-NH2 1group of donors, 0.47% oxygen 0.010283 as acceptor 0.10092 hormone binding molecular_function 1 0.47% 0.012749 0.029316 coreceptor activity molecular_function 1 0.47% 0.012749 0.118989 protein kinase B bindingmolecular_function 1 0.47% 0.012749 0.118989 retinol dehydrogenasemolecular_function activity 1 0.47% 0.012749 0.118989 voltage-gated ion channelmolecular_function activity 3 1.40% 0.014488 0.03178 ligand-dependent nuclearmolecular_function receptor transcription 2 coactivator activity 0.93% 0.015412 0.03373

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RNA polymerase IImolecular_function transcription factor binding 2 0.93% 0.015412 0.13974 deaminase activity molecular_function 1 0.47% 0.015455 0.138806 adenylate kinase activitymolecular_function 1 0.47% 0.015455 0.138806 NAD(P)+-protein-argininemolecular_function ADP-ribosyltransferase 1 activity 0.47% 0.015455 0.138806 protein kinase A catalyticmolecular_function subunit binding 1 0.47% 0.015455 0.138806 protein kinase inhibitormolecular_function activity 1 0.47% 0.015455 0.138806 enzyme regulator activitymolecular_function 1 0.47% 0.015455 0.138806 protein tyrosine phosphatasemolecular_function activity 4 1.87% 0.015504 0.031878 TBP-class protein bindingmolecular_function 1 0.47% 0.018396 0.03734 vinculin binding molecular_function 1 0.47% 0.018396 0.156363 phospholipase activitymolecular_function 1 0.47% 0.018396 0.156363 alpha-actinin bindingmolecular_function 1 0.47% 0.018396 0.156363 NAD binding molecular_function 2 0.93% 0.019627 0.165357 S100 protein bindingmolecular_function 1 0.47% 0.021564 0.178512 calcium-transportingmolecular_function ATPase activity 1 0.47% 0.021564 0.178512 copper ion binding molecular_function 2 0.93% 0.022773 0.042262 carboxy-lyase activitymolecular_function 1 0.47% 0.02856 0.226575 carbonate dehydratasemolecular_function activity 1 0.47% 0.02856 0.226575 nucleobase-containingmolecular_function compound kinase activity 1 0.47% 0.02856 0.226575 phosphatidylserine molecular_functionbinding 1 0.47% 0.032376 0.252638 structural constituentmolecular_function of eye lens Draft 1 0.47% 0.032376 0.252638 receptor signaling proteinmolecular_function activity 1 0.47% 0.036396 0.279429 phosphatase activitymolecular_function 4 1.87% 0.036895 0.061837 p53 binding molecular_function 2 0.93% 0.040355 0.067401 calcium-dependentmolecular_function cysteine-type endopeptidase 1 activity 0.47% 0.040615 0.067716 cysteine-type endopeptidasemolecular_function inhibitor activity invo 1lved in apoptotic 0.47% process 0.040615 0.302077 alpha-tubulin bindingmolecular_function 1 0.47% 0.040615 0.302077 protein kinase activatormolecular_function activity 1 0.47% 0.040615 0.302077 RNA polymerase IImolecular_function transcription coactivator activit 1y 0.47% 0.040615 0.302077 voltage-gated sodiummolecular_function channel activity 1 0.47% 0.040615 0.302077 NADH dehydrogenasemolecular_function (ubiquinone) activity 1 0.47% 0.045028 0.332297 cation channel activitymolecular_function 1 0.47% 0.045028 0.332297 nucleoside diphosphatemolecular_function kinase activity 1 0.47% 0.049628 0.357922 adenyl nucleotide bindingmolecular_function 1 0.47% 0.049628 0.357922 electron carrier activitymolecular_function 2 0.93% 0.049998 0.078544 extracellular matrixmolecular_function binding 1 0.47% 0.054411 0.386558 lyase activity molecular_function 2 0.93% 0.057969 0.089444 R-SMAD binding molecular_function 1 0.47% 0.059371 0.412561 DNA binding molecular_function 7 3.27% 0.062303 0.094748 protein complex scaffoldmolecular_function 1 0.47% 0.069803 0.471292 syntaxin binding molecular_function 1 0.47% 0.075265 0.504592 protein kinase C bindingmolecular_function 1 0.47% 0.075265 0.504592 pyridoxal phosphatemolecular_function binding 2 0.93% 0.075798 0.111702 protein C-terminus molecular_functionbinding 3 1.40% 0.080006 0.117177 glutathione transferasemolecular_function activity 1 0.47% 0.080884 0.118283 cholesterol binding molecular_function 1 0.47% 0.080884 0.523823 extracellular matrixmolecular_function structural constituent 1 0.47% 0.092578 0.57604

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insulin receptor bindingmolecular_function 1 0.47% 0.092578 0.57604 oxidoreductase activity,molecular_function acting on paired donors, 1 with incorporation 0.47% or 0.092578reduction of molecular 0.57604 oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen protein serine/threoninemolecular_function phosphatase activity 1 0.47% 0.098643 0.140161 drug binding molecular_function 1 0.47% 0.098643 0.605856 hydrolase activity, molecular_functionacting on glycosyl bonds 1 0.47% 0.098643 0.605856 protein binding, bridgingmolecular_function 1 0.47% 0.104847 0.635758 RNA polymerase IImolecular_function activating transcription factor 1 binding 0.47% 0.111186 0.154074 identical protein bindingmolecular_function 8 3.74% 0.111793 0.154019 zinc ion binding molecular_function 18 8.41% 0.114372 0.157344 binding molecular_function 1 0.47% 0.117504 0.161187 protein disulfide oxidoreductasemolecular_function activity 1 0.47% 0.137808 0.77629 protein binding molecular_function 117 54.67% 0.155511 0.204767 catalytic activity molecular_function 12 5.61% 0.166016 0.216503 RNA polymerase IImolecular_function transcription regulatory region 1 sequence-specific 0.47% DNA 0.181104 binding 0.232674 transcription factor activity involved in positive regulation of transcription cation-transportingmolecular_function ATPase activity 1 0.47% 0.181104 0.942138 kinase binding molecular_function 1 0.47% 0.181104 0.942138 chaperone binding molecular_function 1 0.47% 0.204051 0.259008 protein heterodimerizationmolecular_function activity 1 0.47% 0.207652 0.262182 transcription corepressormolecular_function activity 2 0.93% 0.24656 0.304442 sequence-specific DNAmolecular_function binding transcription factor 5 activity 2.34% 0.261085 0.318249 ubiquitin-protein transferasemolecular_function activity Draft 4 1.87% 0.26256 0.31923 oxidoreductase activitymolecular_function 8 3.74% 0.271146 0.326748 kinase activity molecular_function 5 2.34% 0.283683 0.339279 metalloendopeptidasemolecular_function activity 2 0.93% 0.356356 0.415749 transporter activity molecular_function 3 1.40% 0.364799 0.423522 transcription coactivatormolecular_function activity 2 0.93% 0.399707 0.45626 protein tyrosine kinasemolecular_function activity 3 1.40% 0.417458 0.472556 Rho guanyl-nucleotidemolecular_function exchange factor activity 1 0.47% 0.452963 0.505534 metallopeptidase activitymolecular_function 2 0.93% 0.463582 0.515572 phosphoprotein phosphatasemolecular_function activity 1 0.47% 0.471094 0.522705 protein complex bindingmolecular_function 1 0.47% 0.480174 0.530924 ATPase activity molecular_function 2 0.93% 0.489633 0.538257 ATP binding molecular_function 17 7.94% 0.492608 0.540903 protein dimerizationmolecular_function activity 2 0.93% 0.515907 0.563884 enzyme binding molecular_function 1 0.47% 0.523405 0.569464 protein kinase activitymolecular_function 4 1.87% 0.524598 0.570111 lipid binding molecular_function 1 0.47% 0.53477 0.579842 GTPase activity molecular_function 1 0.47% 0.542465 0.586849 magnesium ion bindingmolecular_function 2 0.93% 0.562295 0.605549 receptor binding molecular_function 1 0.47% 0.587512 0.630566 sequence-specific DNAmolecular_function binding 5 2.34% 0.627571 0.666795 monooxygenase activitymolecular_function 1 0.47% 0.634582 0.673492 transferase activity,molecular_function transferring phosphorus-conta 7ining groups 3.27% 0.658987 0.697838 cysteine-type peptidasemolecular_function activity 1 0.47% 0.706196 0.741234 oxidoreductase activity,molecular_function acting on paired donors, 1 with incorporation 0.47% or 0.723902reduction of 0.758981 molecular oxygen protein serine/threoninemolecular_function kinase activity 3 1.40% 0.754197 0.786413 protein kinase bindingmolecular_function 2 0.93% 0.757671 0.789171

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GTP binding molecular_function 4 1.87% 0.770198 0.800468 protein domain specificmolecular_function binding 1 0.47% 0.785106 0.814184 serine-type peptidasemolecular_function activity 1 0.47% 0.894985 0.914191 transferase activity molecular_function 6 2.80% 0.918583 0.933288 peptidase activity molecular_function 3 1.40% 0.954944 0.965081 RNA polymerase IImolecular_function core promoter proximal region 1 sequence-specific 0.47% DNA 0.962655 binding 0.970813 hydrolase activity molecular_function 9 4.21% 0.987836 0.992004 transferase activity,molecular_function transferring glycosyl groups 1 0.47% 0.993224 0.995315 nucleotide binding molecular_function 17 7.94% 0.999516 0.999516 Z disc cellular_component 18 8.41% 5.77E-19 5.50E-16 I band cellular_component 10 4.67% 7.41E-15 3.53E-12 myofibril cellular_component 10 4.67% 2.94E-13 6.99E-11 M band cellular_component 7 3.27% 4.10E-11 6.51E-09 sarcoplasmic reticulumcellular_component 8 3.74% 2.80E-10 3.33E-08 T-tubule cellular_component 7 3.27% 1.89E-09 1.63E-07 A band cellular_component 5 2.34% 1.10E-08 8.08E-07 contractile fiber cellular_component 5 2.34% 4.99E-08 3.39E-06 sarcoplasmic reticulumcellular_component membrane 5 2.34% 7.62E-08 3.63E-06 sarcomere cellular_component 6 2.80% 8.03E-08 3.48E-06 actin cytoskeletoncellular_component 12 5.61% 1.93E-07 7.98E-06 troponin complex cellular_componentDraft 3 1.40% 3.08E-06 9.77E-05 myosin complex cellular_component 6 2.80% 3.48E-06 0.000127 cytoskeleton cellular_component 10 4.67% 5.93E-05 0.001129 striated muscle thincellular_component filament 2 0.93% 7.24E-05 0.001813 sarcoplasmic reticulumcellular_component lumen 2 0.93% 7.24E-05 0.001813 sarcolemma cellular_component 5 2.34% 7.76E-05 0.00121 stress fiber cellular_component 5 2.34% 8.68E-05 0.001332 dystroglycan complexcellular_component 2 0.93% 0.000199 0.002492 muscle tendon junctioncellular_component 2 0.93% 0.000199 0.003865 filamentous actin cellular_component 3 1.40% 0.00028 0.003177 mitochondrial respiratorycellular_component chain complex IV 2 0.93% 0.000296 0.005311 junctional membranecellular_component complex 2 0.93% 0.000296 0.005311 sarcoglycan complexcellular_component 2 0.93% 0.000296 0.005311 voltage-gated calciumcellular_component channel complex 3 1.40% 0.000399 0.004088 myosin filament cellular_component 1 0.47% 0.0009 0.014048 longitudinal sarcoplasmiccellular_component reticulum 1 0.47% 0.0009 0.014048 H zone cellular_component 1 0.47% 0.0009 0.014048 lipid tube cellular_component 1 0.47% 0.0009 0.014048 calcium ion-transportingcellular_component ATPase complex 1 0.47% 0.0009 0.014048 terminal cisterna cellular_component 1 0.47% 0.0009 0.014048 transcription exportcellular_component complex 2 1 0.47% 0.0009 0.014048 dystrophin-associatedcellular_component glycoprotein complex 2 0.93% 0.00097 0.014661 fascia adherens cellular_component 2 0.93% 0.001223 0.0064 synaptic vesicle cellular_component 4 1.87% 0.0015 0.007598 bleb cellular_component 1 0.47% 0.001786 0.024635 DUBm complex cellular_component 1 0.47% 0.001786 0.024635 muscle myosin complexcellular_component 1 0.47% 0.001786 0.024635

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female germ cell nucleuscellular_component 1 0.47% 0.001786 0.024635 GMP reductase complexcellular_component 1 0.47% 0.001786 0.024635 costamere cellular_component 2 0.93% 0.001848 0.007392 plasma membranecellular_component 12 5.61% 0.001984 0.007839 extracellular matrix cellular_component 8 3.74% 0.002435 0.009502 6-phosphofructokinasecellular_component complex 1 0.47% 0.002952 0.035123 apical dendrite cellular_component 1 0.47% 0.004391 0.04918 integral componentcellular_component of membrane 21 9.81% 0.005833 0.017353 outer dense fiber cellular_component 1 0.47% 0.006097 0.063787 SAGA complex cellular_component 1 0.47% 0.006097 0.063787 actomyosin contractilecellular_component ring 1 0.47% 0.006097 0.063787 euchromatin cellular_component 1 0.47% 0.006097 0.063787 phosphopyruvate hydratasecellular_component complex 1 0.47% 0.006097 0.063787 Cul5-RING ubiquitincellular_component ligase complex 1 0.47% 0.006097 0.063787 mitochondrial respiratorycellular_component chain 1 0.47% 0.008063 0.081664 smooth endoplasmiccellular_component reticulum 1 0.47% 0.010283 0.10092 sodium channel complexcellular_component 1 0.47% 0.010283 0.10092 intercalated disc cellular_component 2 0.93% 0.010705 0.024978 neuromuscular junctioncellular_component 2 0.93% 0.011786 0.112207 axon terminus cellular_component 1 0.47% 0.012749 0.118989 sodium:potassium-exchangingcellular_component ATPase complexDraft 1 0.47% 0.012749 0.118989 sperm flagellum cellular_component 1 0.47% 0.015455 0.033669 node of Ranvier cellular_component 1 0.47% 0.018396 0.156363 nuclear envelope lumencellular_component 1 0.47% 0.018396 0.156363 perikaryon cellular_component 1 0.47% 0.021564 0.041556 podosome cellular_component 1 0.47% 0.021564 0.178512 septin complex cellular_component 1 0.47% 0.021564 0.178512 microtubule associatedcellular_component complex 1 0.47% 0.024954 0.203044 nuclear inner membranecellular_component 1 0.47% 0.024954 0.203044 inclusion body cellular_component 1 0.47% 0.024954 0.203044 endoplasmic reticulumcellular_component membrane 5 2.34% 0.027174 0.048627 voltage-gated sodiumcellular_component channel complex 1 0.47% 0.032376 0.252638 mitochondrial membranecellular_component 2 0.93% 0.033865 0.262107 sperm principal piececellular_component 1 0.47% 0.040615 0.302077 integral componentcellular_component of endoplasmic reticulum membran 2e 0.93% 0.045035 0.072299 collagen trimer cellular_component 2 0.93% 0.047481 0.345053 cleavage furrow cellular_component 1 0.47% 0.049628 0.357922 Cul3-RING ubiquitincellular_component ligase complex 1 0.47% 0.059371 0.091458 cytoplasmic ribonucleoproteincellular_component granule 1 0.47% 0.059371 0.412561 focal adhesion cellular_component 7 3.27% 0.061139 0.093127 cytoplasmic vesiclecellular_component membrane 1 0.47% 0.075265 0.504592 cell cortex cellular_component 2 0.93% 0.075798 0.504614 cortical cytoskeletoncellular_component 1 0.47% 0.086657 0.549983 respiratory chain cellular_component 1 0.47% 0.092578 0.132932 mitochondrial intermembranecellular_component space 1 0.47% 0.092578 0.57604 large ribosomal subunitcellular_component 1 0.47% 0.092578 0.57604 basement membranecellular_component 2 0.93% 0.096087 0.136734

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dendritic spine cellular_component 1 0.47% 0.098643 0.605856 nuclear pore cellular_component 1 0.47% 0.111186 0.665715 postsynaptic densitycellular_component 1 0.47% 0.124252 0.708309 growth cone cellular_component 1 0.47% 0.13097 0.176606 actin filament cellular_component 1 0.47% 0.137808 0.77629 caveola cellular_component 1 0.47% 0.151822 0.201582 ruffle membrane cellular_component 1 0.47% 0.151822 0.845231 centrosome cellular_component 1 0.47% 0.173832 0.224238 filopodium cellular_component 1 0.47% 0.188665 0.240763 nucleus cellular_component 39 18.22% 0.217314 0.273654 voltage-gated potassiumcellular_component channel complex 1 0.47% 0.219767 0.276377 membrane raft cellular_component 2 0.93% 0.225266 0.282919 mitochondrial innercellular_component membrane 3 1.40% 0.369692 0.428159 integral componentcellular_component of plasma membrane 1 0.47% 0.372888 0.43029 proteinaceous extracellularcellular_component matrix 2 0.93% 0.406 0.462889 Golgi apparatus cellular_component 4 1.87% 0.431652 0.487465 cell surface cellular_component 2 0.93% 0.435062 0.488996 cell-cell junction cellular_component 2 0.93% 0.470071 0.52218 nucleolus cellular_component 4 1.87% 0.476413 0.527378 peroxisome cellular_component 1 0.47% 0.489263 0.53972 midbody cellular_componentDraft 1 0.47% 0.525665 0.570619 perinuclear region ofcellular_component cytoplasm 4 1.87% 0.540566 0.585459 trans-Golgi networkcellular_component 1 0.47% 0.571168 0.613715 neuron projection cellular_component 1 0.47% 0.607467 0.648328 receptor complex cellular_component 1 0.47% 0.66157 0.699794 protein complex cellular_component 3 1.40% 0.672684 0.709973 intracellular membrane-boundedcellular_component organelle 3 1.40% 0.732158 0.766792 external side of plasmacellular_component membrane 1 0.47% 0.766876 0.797887 nuclear membrane cellular_component 1 0.47% 0.776441 0.806076 transcription factorcellular_component complex 1 0.47% 0.806106 0.834145 nucleoplasm cellular_component 1 0.47% 0.836483 0.861831 synapse cellular_component 1 0.47% 0.896216 0.914467 cytosol cellular_component 7 3.27% 0.897641 0.91494 apical plasma membranecellular_component 1 0.47% 0.911394 0.926974 cytoplasm cellular_component 39 18.22% 0.929728 0.9426 lysosomal membranecellular_component 1 0.47% 0.991257 0.994391 muscle contraction biological_process 11 5.14% 3.34E-14 1.06E-11 cardiac muscle contractionbiological_process 9 4.21% 4.07E-11 7.76E-09 ventricular cardiac biological_processmuscle tissue morphogenesis 7 3.27% 1.89E-09 1.80E-07 skeletal muscle contractionbiological_process 5 2.34% 1.10E-08 9.55E-07 striated muscle contractionbiological_process 5 2.34% 1.91E-08 1.21E-06 signal transduction biological_process 1 0.47% 3.73E-08 2.22E-06 cardiac muscle tissuebiological_process morphogenesis 5 2.34% 4.99E-08 2.79E-06 sarcomere organizationbiological_process 6 2.80% 6.09E-08 3.05E-06 regulation of the forcebiological_process of heart contraction 5 2.34% 7.62E-08 4.54E-06 skeletal muscle cellbiological_process differentiation 7 3.27% 3.01E-07 1.19E-05 cardiac myofibril assemblybiological_process 4 1.87% 1.03E-06 3.76E-05

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regulation of releasebiological_process of sequestered calcium ion 4 into cytosol by 1.87% sarcoplasmic 1.52E-06 reticulum 5.38E-05 regulation of striatedbiological_process muscle contraction 3 1.40% 3.08E-06 0.000117 regulation of ATPasebiological_process activity 3 1.40% 3.08E-06 0.000117 G-protein coupled receptorbiological_process signaling pathway 2 0.93% 1.10E-05 0.000283 skeletal muscle fiberbiological_process development 4 1.87% 1.24E-05 0.000312 plasma membrane repairbiological_process 3 1.40% 1.41E-05 0.000344 regulation of calcium-transportingbiological_process ATPase activity 2 0.93% 3.65E-05 0.000869 negative regulationbiological_process of calcium ion binding 2 0.93% 3.65E-05 0.001087 negative regulationbiological_process of calcium ion transmembrane 2 transporter activity 0.93% 3.65E-05 0.001087 sarcoplasmic reticulumbiological_process calcium ion transport 2 0.93% 3.65E-05 0.001087 detection of musclebiological_process stretch 2 0.93% 3.65E-05 0.001087 regulation of myoblastbiological_process differentiation 2 0.93% 7.24E-05 0.001351 cellular response tobiological_process caffeine 2 0.93% 7.24E-05 0.001813 regulation of relaxationbiological_process of muscle 2 0.93% 7.24E-05 0.001813 muscle filament slidingbiological_process 2 0.93% 7.24E-05 0.001813 muscle cell cellularbiological_process homeostasis 3 1.40% 9.58E-05 0.001448 muscle organ developmentbiological_process 4 1.87% 0.0001 0.001491 adult heart developmentbiological_process 3 1.40% 0.000122 0.001786 regulation of calciumbiological_process ion transport 3 1.40% 0.000122 0.00258 cardiac muscle fiberbiological_process development 2 0.93% 0.000125 0.001783 skeletal muscle thinbiological_process filament assembly Draft 2 0.93% 0.000125 0.002597 release of sequesteredbiological_process calcium ion into cytosol 2by sarcoplasmic 0.93% reticulum 0.000125 0.002597 negative regulationbiological_process of potassium ion transmembrane 2 transporter 0.93% activity 0.000125 0.002597 hydrogen ion transmembranebiological_process transport 5 2.34% 0.000133 0.001707 calcium ion transportbiological_process 6 2.80% 0.000145 0.001835 negative regulationbiological_process of calcium ion import 2 0.93% 0.000199 0.003865 myofibril assembly biological_process 2 0.93% 0.000199 0.003865 response to activity biological_process 2 0.93% 0.000199 0.003865 regulation of cardiacbiological_process muscle contraction by regulat 2ion of the release 0.93% of 0.000199sequestered 0.003865 calcium ion cardiac muscle hypertrophybiological_process 2 0.93% 0.000199 0.003865 collagen fibril organizationbiological_process 4 1.87% 0.000229 0.002623 glycolytic processbiological_process 4 1.87% 0.000292 0.003266 negative regulationbiological_process of potassium ion transport 2 0.93% 0.000296 0.003273 regulation of calciumbiological_process ion import 2 0.93% 0.000296 0.005311 negative regulationbiological_process of protein import into nucleus 2 0.93% 0.000296 0.005311 response to musclebiological_process activity 2 0.93% 0.000418 0.004238 negative regulationbiological_process of calcium ion transport 2 0.93% 0.000418 0.007244 glycogen metabolicbiological_process process 3 1.40% 0.000551 0.005298 regulation of heart biological_processrate 3 1.40% 0.000551 0.009042 regulation of musclebiological_process contraction 2 0.93% 0.000753 0.006895 nucleotide metabolicbiological_process process 2 0.93% 0.000753 0.011951 negative regulationbiological_process of protein phosphatase type 1 2B activity 0.47% 0.0009 0.008009 positive regulation biological_processof heart rate by epinephrine 1 0.47% 0.0009 0.014048 muscle tissue developmentbiological_process 1 0.47% 0.0009 0.014048 heart growth biological_process 1 0.47% 0.0009 0.014048 IMP salvage biological_process 1 0.47% 0.0009 0.014048 muscle structure developmentbiological_process 1 0.47% 0.0009 0.014048

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negative regulationbiological_process of vasodilation 1 0.47% 0.0009 0.014048 muscle system processbiological_process 1 0.47% 0.0009 0.014048 negative regulationbiological_process of N-terminal protein palmitoyl 1ation 0.47% 0.0009 0.014048 autolysis biological_process 1 0.47% 0.0009 0.014048 regulation of the forcebiological_process of heart contraction by car 1diac conduction 0.47% 0.0009 0.014048 negative regulationbiological_process of sarcomere organization 1 0.47% 0.0009 0.014048 negative regulationbiological_process of T cell migration 1 0.47% 0.0009 0.014048 positive regulation biological_processof oxygen metabolic process 1 0.47% 0.0009 0.014048 naphthalene metabolicbiological_process process 1 0.47% 0.0009 0.014048 skeletal muscle fiberbiological_process differentiation 1 0.47% 0.0009 0.014048 corticospinal neuronbiological_process axon guidance 1 0.47% 0.0009 0.014048 positive regulation biological_processof protein depolymerization 1 0.47% 0.0009 0.014048 forward locomotionbiological_process 1 0.47% 0.0009 0.014048 response to musclebiological_process stretch 1 0.47% 0.0009 0.014048 regulation of tissuebiological_process remodeling 1 0.47% 0.0009 0.014048 skeletal muscle adaptationbiological_process 1 0.47% 0.0009 0.014048 skeletal muscle myosinbiological_process thick filament assembly 1 0.47% 0.0009 0.014048 positive regulation biological_processof fast-twitch skeletal muscle 1 fiber contraction 0.47% 0.0009 0.014048 sarcomerogenesis biological_process 1 0.47% 0.0009 0.014048 tendon sheath developmentbiological_process 1 0.47% 0.0009 0.014048 regulation of signalbiological_process transduction by receptor interDraft 1nalization 0.47% 0.0009 0.014048 regulation of skeletalbiological_process muscle adaptation 1 0.47% 0.0009 0.014048 regulation of proteinbiological_process glycosylation 1 0.47% 0.0009 0.014048 muscle cell fate specificationbiological_process 1 0.47% 0.0009 0.014048 regulation of nervebiological_process growth factor receptor activity 1 0.47% 0.0009 0.014048 regulation of myoblastbiological_process proliferation 1 0.47% 0.0009 0.014048 negative regulationbiological_process of dermatome development 1 0.47% 0.0009 0.014048 adrenergic receptorbiological_process signaling pathway involved 1 in heart process 0.47% 0.0009 0.014048 positive regulation biological_processof lysosomal membrane permeabil 1ity 0.47% 0.0009 0.014048 negative regulationbiological_process of calcium-transporting ATPase 1 activity 0.47% 0.0009 0.014048 cadmium ion homeostasisbiological_process 1 0.47% 0.0009 0.014048 tendon formation biological_process 1 0.47% 0.0009 0.014048 regulation of musclebiological_process filament sliding 1 0.47% 0.0009 0.014048 evasion or tolerancebiological_process of host defense response 1 0.47% 0.0009 0.014048 membrane depolarizationbiological_process during Purkinje myocyte 1 cell action 0.47%potential 0.0009 0.014048 positive regulation biological_processof peptidyl-serine dephosphoryl 1ation 0.47% 0.0009 0.014048 negative regulationbiological_process of lipoprotein lipid oxidation 1 0.47% 0.0009 0.014048 phosphocreatine biosyntheticbiological_process process 1 0.47% 0.0009 0.014048 negative regulationbiological_process of hepatocyte differentiation 1 0.47% 0.0009 0.014048 regulation of cell communicationbiological_process by electrical coup 1ling 0.47% 0.0009 0.014048 regulation of musclebiological_process filament sliding speed 1 0.47% 0.0009 0.014048 regulation of responsebiological_process to food 1 0.47% 0.0009 0.014048 positive regulation biological_processof endoplasmic reticulum calciu 1m ion concentration 0.47% 0.0009 0.014048 interleukin-33-mediatedbiological_process signaling pathway 1 0.47% 0.0009 0.014048 regulation of sodiumbiological_process ion transmembrane transporter 2 activity 0.93% 0.00097 0.005189 muscle cell differentiationbiological_process 2 0.93% 0.00097 0.014661 glycogen biosyntheticbiological_process process 2 0.93% 0.001223 0.017919

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negative regulationbiological_process of signal transduction 2 0.93% 0.001223 0.017919 myotube differentiationbiological_process 2 0.93% 0.001223 0.017919 regulation of ventricularbiological_process cardiac muscle cell membr 2ane repolarization 0.93% 0.001515 0.007633 regulation of G2/Mbiological_process transition of mitotic cell cycle 2 0.93% 0.001515 0.021215 myoblast fusion biological_process 2 0.93% 0.001515 0.021215 heart contraction biological_process 2 0.93% 0.001515 0.021215 regulation of calciumbiological_process ion transmembrane transporter 1 activity 0.47% 0.001786 0.008807 negative regulationbiological_process of monocyte chemotactic protein 1-1 production 0.47% 0.001786 0.024635 negative regulationbiological_process of cell development 1 0.47% 0.001786 0.024635 regulation of membranebiological_process depolarization during cardia 1c muscle cell 0.47% action 0.001786 potential 0.024635 self proteolysis biological_process 1 0.47% 0.001786 0.024635 regulation of skeletalbiological_process muscle contraction by regula 1tion of release 0.47% of sequestered 0.001786 calcium 0.024635 ion negative regulationbiological_process of ATP citrate synthase activit 1y 0.47% 0.001786 0.024635 G1 to G0 transitionbiological_process involved in cell differentiatio 1n 0.47% 0.001786 0.024635 negative regulationbiological_process of oxidoreductase activity 1 0.47% 0.001786 0.024635 relaxation of skeletalbiological_process muscle 1 0.47% 0.001786 0.024635 negative regulationbiological_process of smooth muscle cell-matrix 1 adhesion 0.47% 0.001786 0.024635 somatic muscle developmentbiological_process 1 0.47% 0.001786 0.024635 tendon developmentbiological_process 1 0.47% 0.001786 0.024635 zinc ion homeostasisbiological_process 1 0.47% 0.001786 0.024635 regulation of skeletalbiological_process muscle contraction Draft 1 0.47% 0.001786 0.024635 thyroid hormone transportbiological_process 1 0.47% 0.001786 0.024635 maintenance of mitochondrionbiological_process location 1 0.47% 0.001786 0.024635 positive regulation biological_processof transcription from RNA polym 1erase II promoter 0.47% in 0.001786 response to 0.024635 oxidative stress lipid tube assembly biological_process 1 0.47% 0.001786 0.024635 negative regulationbiological_process of striated muscle contraction 1 0.47% 0.001786 0.024635 negative regulationbiological_process of T-helper 1 type immune 1response 0.47% 0.001786 0.024635 cellular response tobiological_process salt stress 1 0.47% 0.001786 0.024635 endothelial cell-cellbiological_process adhesion 1 0.47% 0.001786 0.024635 spongiotrophoblastbiological_process differentiation 1 0.47% 0.001786 0.024635 positive regulation biological_processof satellite cell activation in 1volved in skeletal 0.47% muscle 0.001786 regeneration 0.024635 striated muscle cellbiological_process development 1 0.47% 0.001786 0.024635 'de novo' AMP biosyntheticbiological_process process 1 0.47% 0.001786 0.024635 negative regulationbiological_process of cytokine production involved 1 in inflammatory 0.47% response 0.001786 0.024635 sequestering of calciumbiological_process ion 1 0.47% 0.001786 0.024635 tendon cell differentiationbiological_process 1 0.47% 0.001786 0.024635 regulation of cell cyclebiological_process arrest 1 0.47% 0.001786 0.024635 extraocular skeletalbiological_process muscle development 1 0.47% 0.001786 0.024635 cellular metal ion homeostasisbiological_process 1 0.47% 0.001786 0.024635 cellular calcium ionbiological_process homeostasis 4 1.87% 0.00189 0.007496 glucose metabolic processbiological_process 3 1.40% 0.002186 0.008598 neuromuscular synapticbiological_process transmission 2 0.93% 0.002644 0.010273 positive regulation biological_processof apoptotic process 7 3.27% 0.002843 0.010957 skeletal muscle tissuebiological_process development 3 1.40% 0.002937 0.011275 skeletal muscle satellitebiological_process cell differentiation 1 0.47% 0.002952 0.011284 purine nucleotide metabolicbiological_process process 1 0.47% 0.002952 0.035123 regulation of skeletalbiological_process muscle cell differentiation 1 0.47% 0.002952 0.035123

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negative regulationbiological_process of necrotic cell death 1 0.47% 0.002952 0.035123 regulation of p38MAPKbiological_process cascade 1 0.47% 0.002952 0.035123 positive regulation biological_processof long-term neuronal synaptic 1 plasticity 0.47% 0.002952 0.035123 cellular lipid catabolicbiological_process process 1 0.47% 0.002952 0.035123 development of primarybiological_process male sexual characteristics 1 0.47% 0.002952 0.035123 actin-mediated cellbiological_process contraction 1 0.47% 0.002952 0.035123 negative regulationbiological_process of planar cell polarity pathway 1 involved in 0.47%axis elongation 0.002952 0.035123 cellular response tobiological_process cadmium ion 1 0.47% 0.002952 0.035123 sclerotome developmentbiological_process 1 0.47% 0.002952 0.035123 negative regulationbiological_process of calcineurin-NFAT signaling 1 cascade 0.47% 0.002952 0.035123 intracellular proteinbiological_process transmembrane transport 1 0.47% 0.002952 0.035123 cellular response tobiological_process X-ray 1 0.47% 0.002952 0.035123 negative regulationbiological_process of protein sumoylation 1 0.47% 0.002952 0.035123 ether lipid metabolicbiological_process process 1 0.47% 0.002952 0.035123 negative regulationbiological_process of mesodermal cell fate specifi 1cation 0.47% 0.002952 0.035123 microspike assemblybiological_process 1 0.47% 0.002952 0.035123 IMP biosynthetic processbiological_process 1 0.47% 0.002952 0.035123 negative regulationbiological_process of cysteine-type endopeptidase 1 activity 0.47% 0.002952 0.035123 actin filament severingbiological_process 1 0.47% 0.002952 0.035123 negative regulationbiological_process of myoblast differentiation 2 0.93% 0.003111 0.010539 protein import into biological_processnucleus, translocation Draft 2 0.93% 0.003626 0.012198 chondrocyte developmentbiological_process 2 0.93% 0.004192 0.014052 ATP biosynthetic processbiological_process 2 0.93% 0.004192 0.047509 regulation of cytoskeletonbiological_process organization 1 0.47% 0.004391 0.014616 regulation of glucosebiological_process import 1 0.47% 0.004391 0.04918 purine ribonucleosidebiological_process monophosphate biosynthetic 1 process 0.47% 0.004391 0.04918 fructose 1,6-bisphosphatebiological_process metabolic process 1 0.47% 0.004391 0.04918 histone modificationbiological_process 1 0.47% 0.004391 0.04918 positive regulation biological_processof mitochondrial depolarization 1 0.47% 0.004391 0.04918 regulation of stem cellbiological_process division 1 0.47% 0.004391 0.04918 leptin-mediated signalingbiological_process pathway 1 0.47% 0.004391 0.04918 negative regulationbiological_process of protein complex disassembly 1 0.47% 0.004391 0.04918 thyroid hormone metabolicbiological_process process 1 0.47% 0.004391 0.04918 fructose 6-phosphatebiological_process metabolic process 1 0.47% 0.004391 0.04918 Wnt signaling pathwaybiological_process involved in somitogenesis 1 0.47% 0.004391 0.04918 negative regulationbiological_process of heart rate 1 0.47% 0.004391 0.04918 negative regulationbiological_process of cell size 1 0.47% 0.004391 0.04918 AMP biosynthetic processbiological_process 1 0.47% 0.004391 0.04918 glycogen catabolic biological_processprocess 1 0.47% 0.004391 0.04918 regulation of establishmentbiological_process of planar polarity 1 0.47% 0.004391 0.04918 caveola assembly biological_process 1 0.47% 0.004391 0.04918 nucleus localizationbiological_process 1 0.47% 0.004391 0.04918 convergent extensionbiological_process involved in organogenesis 1 0.47% 0.004391 0.04918 negative regulationbiological_process of nitric-oxide synthase activi 1ty 0.47% 0.004391 0.04918 positive regulation biological_processof brown fat cell differentiati 1on 0.47% 0.004391 0.04918 mRNA modificationbiological_process 1 0.47% 0.004391 0.04918 heart morphogenesisbiological_process 3 1.40% 0.004561 0.01383

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negative regulationbiological_process of catalytic activity 3 1.40% 0.004561 0.050494 cardiac muscle tissuebiological_process development 2 0.93% 0.00481 0.01449 endoplasmic reticulumbiological_process organization 2 0.93% 0.00481 0.052629 somitogenesis biological_process 3 1.40% 0.004948 0.014812 calcium ion transmembranebiological_process transport 4 1.87% 0.005648 0.016857 muscle tissue morphogenesisbiological_process 1 0.47% 0.006097 0.018083 negative regulationbiological_process of heart contraction 1 0.47% 0.006097 0.063787 membrane raft organizationbiological_process 1 0.47% 0.006097 0.063787 positive regulation biological_processof potassium ion transmembrane 1 transporter 0.47% activity 0.006097 0.063787 regulation of ventricularbiological_process cardiac muscle cell membr 1ane depolarization 0.47% 0.006097 0.063787 positive regulation biological_processof interleukin-5 production 1 0.47% 0.006097 0.063787 negative regulationbiological_process of DNA biosynthetic process 1 0.47% 0.006097 0.063787 cornea developmentbiological_process in camera-type eye 1 0.47% 0.006097 0.063787 positive regulation biological_processof necrotic cell death 1 0.47% 0.006097 0.063787 cellular response tobiological_process nitric oxide 1 0.47% 0.006097 0.063787 positive regulation biological_processof endopeptidase activity 1 0.47% 0.006097 0.063787 muscle cell developmentbiological_process 1 0.47% 0.006097 0.063787 myoblast migration biological_process 1 0.47% 0.006097 0.063787 negative regulationbiological_process of protein localization to cell 1 surface 0.47% 0.006097 0.063787 convergent extensionbiological_process involved in axis elongation 1 0.47% 0.006097 0.063787 positive regulation biological_processof potassium ion transport Draft 1 0.47% 0.006097 0.063787 membrane depolarizationbiological_process during cardiac muscle 1 cell action potential 0.47% 0.006097 0.063787 positive regulation biological_processof sequestering of triglyceride 1 0.47% 0.006097 0.063787 positive regulation biological_processof dendritic spine development 1 0.47% 0.006097 0.063787 regulation of ryanodine-sensitivebiological_process calcium-release 1 channel activity 0.47% 0.006097 0.063787 midbrain-hindbrainbiological_process boundary development 1 0.47% 0.006097 0.063787 positive regulation biological_processof epidermal growth factor-acti 1vated receptor 0.47% activity 0.006097 0.063787 enucleate erythrocytebiological_process differentiation 1 0.47% 0.008063 0.021089 negative regulationbiological_process of protein kinase activity by 1 regulation of protein 0.47% phosphorylation 0.008063 0.081664 negative regulationbiological_process of platelet-derived growth fact 1or receptor signaling 0.47% 0.008063pathway 0.081664 proteoglycan metabolicbiological_process process 1 0.47% 0.008063 0.081664 otic vesicle formationbiological_process 1 0.47% 0.008063 0.081664 negative regulationbiological_process of cartilage development 1 0.47% 0.008063 0.081664 ossification involvedbiological_process in bone maturation 1 0.47% 0.008063 0.081664 neural crest cell differentiationbiological_process 1 0.47% 0.008063 0.081664 negative regulationbiological_process of focal adhesion assembly 1 0.47% 0.008063 0.081664 energy reserve metabolicbiological_process process 1 0.47% 0.008063 0.081664 basement membranebiological_process organization 1 0.47% 0.008063 0.081664 oxidative phosphorylationbiological_process 1 0.47% 0.008063 0.081664 regulation of branchingbiological_process involved in mammary gland 1 duct morphogenesis 0.47% 0.008063 0.081664 negative regulationbiological_process of cardiac muscle hypertrophy 1 0.47% 0.008063 0.081664 fructose metabolic biological_processprocess 1 0.47% 0.008063 0.081664 cholesterol catabolicbiological_process process 1 0.47% 0.008063 0.081664 negative regulationbiological_process of cAMP-dependent protein 1 kinase activity 0.47% 0.008063 0.081664 forebrain neuron developmentbiological_process 1 0.47% 0.008063 0.081664 synaptic transmission,biological_process cholinergic 1 0.47% 0.008063 0.081664 regulation of cardiacbiological_process muscle cell contraction 1 0.47% 0.008063 0.081664

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negative regulationbiological_process of cell growth 4 1.87% 0.009944 0.024462 regulation of atrial biological_processcardiac muscle cell membrane 1 depolarization 0.47% 0.010283 0.025165 cellular response tobiological_process dexamethasone stimulus 1 0.47% 0.010283 0.10092 forebrain neuron differentiationbiological_process 1 0.47% 0.010283 0.10092 SNARE complex assemblybiological_process 1 0.47% 0.010283 0.10092 locomotion biological_process 1 0.47% 0.010283 0.10092 cardiac conduction biological_process 1 0.47% 0.010283 0.10092 response to unfoldedbiological_process protein 1 0.47% 0.010283 0.10092 neuronal action potentialbiological_process propagation 1 0.47% 0.010283 0.10092 negative regulationbiological_process of platelet aggregation 1 0.47% 0.010283 0.10092 positive regulation biological_processof chemokine secretion 1 0.47% 0.010283 0.10092 negative regulationbiological_process of endoplasmic reticulum calciu 1m ion concentration 0.47% 0.010283 0.10092 negative regulationbiological_process of cardiac muscle cell apoptoti 1c process 0.47% 0.010283 0.10092 sperm axoneme assemblybiological_process 1 0.47% 0.010283 0.10092 cellular response tobiological_process calcium ion 2 0.93% 0.010705 0.10399 regulation of membranebiological_process potential 3 1.40% 0.011452 0.026592 endodermal cell differentiationbiological_process 2 0.93% 0.011786 0.027301 protein dephosphorylationbiological_process 5 2.34% 0.012166 0.028043 removal of superoxidebiological_process radicals 1 0.47% 0.012749 0.118989 cardiac muscle cellbiological_process development 1 0.47% 0.012749 0.118989 negative regulationbiological_process of JUN kinase activity Draft 1 0.47% 0.012749 0.118989 protein targeting tobiological_process membrane 1 0.47% 0.012749 0.118989 positive regulation biological_processof DNA damage response, signal 1 transduction 0.47% by p53 0.012749 class mediator 0.118989 regulation of proteinbiological_process kinase B signaling 1 0.47% 0.012749 0.118989 somite developmentbiological_process 1 0.47% 0.012749 0.118989 cardiac muscle cellbiological_process action potential involved in 1contraction 0.47% 0.012749 0.118989 cardiac left ventriclebiological_process morphogenesis 1 0.47% 0.012749 0.118989 positive regulation biological_processof nuclear-transcribed mRNA 1 poly(A) tail shortening 0.47% 0.012749 0.118989 protein localizationbiological_process to membrane 1 0.47% 0.012749 0.118989 positive regulation biological_processof synapse maturation 1 0.47% 0.012749 0.118989 positive regulation biological_processof myotube differentiation 1 0.47% 0.012749 0.118989 peptidyl-tyrosine dephosphorylationbiological_process 4 1.87% 0.014252 0.031334 branching involvedbiological_process in labyrinthine layer morphogene 1sis 0.47% 0.015455 0.138806 nucleoside triphosphatebiological_process biosynthetic process 1 0.47% 0.015455 0.138806 positive regulation biological_processof macrophage activation 1 0.47% 0.015455 0.138806 positive regulation biological_processof vasoconstriction 1 0.47% 0.015455 0.138806 zinc ion transport biological_process 1 0.47% 0.015455 0.138806 response to reactivebiological_process oxygen species 1 0.47% 0.015455 0.138806 protein N-linked glycosylationbiological_process via asparagine 1 0.47% 0.015455 0.138806 monovalent inorganicbiological_process cation transport 1 0.47% 0.015455 0.138806 positive regulation biological_processof megakaryocyte differentiatio 1n 0.47% 0.015455 0.138806 cellular zinc ion homeostasisbiological_process 1 0.47% 0.015455 0.138806 positive regulation biological_processof astrocyte differentiation 1 0.47% 0.015455 0.138806 positive regulation biological_processof receptor activity 1 0.47% 0.015455 0.138806 positive regulation biological_processof catenin import into nucleus 1 0.47% 0.015455 0.138806 positive regulation biological_processof mitochondrial calcium ion 1 concentration 0.47% 0.015455 0.138806 muscle organ morphogenesisbiological_process 1 0.47% 0.015455 0.138806

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astrocyte developmentbiological_process 1 0.47% 0.015455 0.138806 histone deubiquitinationbiological_process 1 0.47% 0.015455 0.138806 regulation of membranebiological_process repolarization 1 0.47% 0.015455 0.138806 nucleotide phosphorylationbiological_process 1 0.47% 0.015455 0.138806 protein ubiquitinationbiological_process 6 2.80% 0.016357 0.03356 cellular response tobiological_process drug 2 0.93% 0.016751 0.034295 regulation of ion transmembranebiological_process transport 3 1.40% 0.018011 0.036795 protein homotetramerizationbiological_process 2 0.93% 0.018156 0.037012 protein polymerizationbiological_process 2 0.93% 0.018156 0.155715 mRNA transport biological_process 1 0.47% 0.018396 0.156363 dentate gyrus developmentbiological_process 1 0.47% 0.018396 0.156363 transcription elongationbiological_process from RNA polymerase1 II promoter 0.47% 0.018396 0.156363 regulation of G1/S biological_processtransition of mitotic cell cycle 1 0.47% 0.018396 0.156363 response to mechanicalbiological_process stimulus 1 0.47% 0.018396 0.156363 activation of proteinbiological_process kinase B activity 1 0.47% 0.018396 0.156363 carboxylic acid metabolicbiological_process process 1 0.47% 0.018396 0.156363 positive regulation biological_processof Rho protein signal transduct 1ion 0.47% 0.018396 0.156363 placenta blood vesselbiological_process development 1 0.47% 0.018396 0.156363 epithelial cell proliferationbiological_process 1 0.47% 0.018396 0.156363 cardiac muscle hypertrophybiological_process in response to stress 1 0.47% 0.018396 0.156363 negative regulationbiological_process of neural precursor cell prolifDraft 1eration 0.47% 0.018396 0.156363 positive regulation biological_processof vascular endothelial growth 1 factor receptor 0.47% signaling 0.018396 pathway 0.156363 plasma membrane organizationbiological_process 1 0.47% 0.018396 0.156363 positive regulation biological_processof fat cell differentiation 2 0.93% 0.019627 0.038211 response to stress biological_process 2 0.93% 0.019627 0.165357 response to endoplasmicbiological_process reticulum stress 2 0.93% 0.019627 0.165357 response to hypoxiabiological_process 3 1.40% 0.02099 0.040533 calcium ion import biological_process 1 0.47% 0.021564 0.178512 positive regulation biological_processof collagen biosynthetic proces 1s 0.47% 0.021564 0.178512 cellular response tobiological_process reactive oxygen species 1 0.47% 0.021564 0.178512 myoblast differentiationbiological_process 1 0.47% 0.021564 0.178512 regulation of I-kappaBbiological_process kinase/NF-kappaB signaling 1 0.47% 0.021564 0.178512 pentose-phosphate biological_processshunt 1 0.47% 0.021564 0.178512 negative regulationbiological_process of reactive oxygen species meta 1bolic process 0.47% 0.021564 0.178512 negative regulationbiological_process of axon extension 1 0.47% 0.021564 0.178512 negative regulationbiological_process of autophagy 1 0.47% 0.021564 0.178512 endothelial cell morphogenesisbiological_process 1 0.47% 0.021564 0.178512 DNA demethylationbiological_process 1 0.47% 0.021564 0.178512 lipid particle organizationbiological_process 1 0.47% 0.021564 0.178512 purine nucleotide biosyntheticbiological_process process 1 0.47% 0.021564 0.178512 planar cell polaritybiological_process pathway involved in neural 1tube closure 0.47% 0.021564 0.178512 hematopoietic stembiological_process cell proliferation 1 0.47% 0.024954 0.046218 JAK-STAT cascadebiological_process 1 0.47% 0.024954 0.203044 negative regulationbiological_process of peptidyl-tyrosine phosphoryl 1ation 0.47% 0.024954 0.203044 negative regulationbiological_process of epithelial to mesenchymal 1 transition 0.47% 0.024954 0.203044 regulation of endocytosisbiological_process 1 0.47% 0.024954 0.203044 muscle fiber developmentbiological_process 1 0.47% 0.024954 0.203044

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regulation of neuronbiological_process differentiation 1 0.47% 0.024954 0.203044 ERK1 and ERK2 cascadebiological_process 1 0.47% 0.024954 0.203044 trophoblast giant cellbiological_process differentiation 1 0.47% 0.024954 0.203044 collagen catabolic processbiological_process 1 0.47% 0.024954 0.203044 membrane depolarizationbiological_process 1 0.47% 0.024954 0.203044 regulation of Wnt signalingbiological_process pathway 1 0.47% 0.024954 0.203044 actin filament organizationbiological_process 2 0.93% 0.026193 0.047137 substantia nigra developmentbiological_process 2 0.93% 0.026193 0.211318 outflow tract morphogenesisbiological_process 2 0.93% 0.026193 0.211318 intrinsic apoptotic signalingbiological_process pathway 1 0.47% 0.02856 0.051011 establishment of proteinbiological_process localization to plasma 1membrane 0.47% 0.02856 0.226575 peroxisome organizationbiological_process 1 0.47% 0.02856 0.226575 cellular response tobiological_process extracellular stimulus 1 0.47% 0.02856 0.226575 regulation of cardiacbiological_process muscle contraction 1 0.47% 0.02856 0.226575 positive regulation biological_processof cell death 1 0.47% 0.02856 0.226575 regulation of transformingbiological_process growth factor beta recep 1tor signaling 0.47% pathway 0.02856 0.226575 positive regulation biological_processof neutrophil chemotaxis 1 0.47% 0.02856 0.226575 focal adhesion assemblybiological_process 1 0.47% 0.02856 0.226575 behavioral responsebiological_process to pain 1 0.47% 0.02856 0.226575 positive regulation biological_processof sodium ion transport 1 0.47% 0.02856 0.226575 heart trabecula formationbiological_processDraft 1 0.47% 0.02856 0.226575 negative regulationbiological_process of Wnt signaling pathway 2 0.93% 0.031842 0.055317 digestive tract morphogenesisbiological_process 1 0.47% 0.032376 0.056142 cytoplasmic microtubulebiological_process organization 1 0.47% 0.032376 0.252638 negative regulationbiological_process of neurogenesis 1 0.47% 0.032376 0.252638 central nervous systembiological_process neuron development 1 0.47% 0.032376 0.252638 protein monoubiquitinationbiological_process 1 0.47% 0.032376 0.252638 negative regulationbiological_process of smooth muscle cell prolifera 1tion 0.47% 0.032376 0.252638 ventricular system biological_processdevelopment 1 0.47% 0.032376 0.252638 negative regulationbiological_process of protein kinase activity 2 0.93% 0.033865 0.057673 negative regulationbiological_process of microtubule depolymerization 1 0.47% 0.036396 0.061763 detection of mechanicalbiological_process stimulus involved in sensor 1y perception 0.47% of sound 0.036396 0.279429 positive regulation biological_processof filopodium assembly 1 0.47% 0.036396 0.279429 positive regulation biological_processof release of cytochrome c from 1 mitochondria 0.47% 0.036396 0.279429 female gonad developmentbiological_process 1 0.47% 0.036396 0.279429 regulation of heart biological_processcontraction 1 0.47% 0.036396 0.279429 negative regulationbiological_process of angiogenesis 2 0.93% 0.038121 0.063781 hindbrain developmentbiological_process 1 0.47% 0.040615 0.302077 camera-type eye morphogenesisbiological_process 1 0.47% 0.040615 0.302077 positive regulation biological_processof release of sequestered calci 1um ion into cytosol 0.47% 0.040615 0.302077 negative regulationbiological_process of insulin receptor signaling 1 pathway 0.47% 0.040615 0.302077 negative regulationbiological_process of interferon-gamma production 1 0.47% 0.040615 0.302077 ATP metabolic processbiological_process 1 0.47% 0.040615 0.302077 positive regulation biological_processof insulin secretion 1 0.47% 0.040615 0.302077 positive regulation biological_processof ATPase activity 1 0.47% 0.045028 0.073276 glucose transport biological_process 1 0.47% 0.045028 0.332297 protein localizationbiological_process to organelle 1 0.47% 0.045028 0.332297

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nucleoside diphosphatebiological_process phosphorylation 1 0.47% 0.045028 0.332297 iron ion homeostasisbiological_process 1 0.47% 0.045028 0.332297 negative regulationbiological_process of MAPK cascade 1 0.47% 0.045028 0.332297 negative regulationbiological_process of cysteine-type endopeptidase 2 activity involved 0.93% in 0.047481apoptotic process 0.076098 ventricular septum biological_processdevelopment 1 0.47% 0.049628 0.079271 cell-cell junction organizationbiological_process 1 0.47% 0.049628 0.357922 positive regulation biological_processof proteolysis 1 0.47% 0.049628 0.357922 intrinsic apoptotic signalingbiological_process pathway in response 1 to endoplasmic 0.47% reticulum 0.049628 stress 0.357922 eye development biological_process 1 0.47% 0.049628 0.357922 post-anal tail morphogenesisbiological_process 1 0.47% 0.049628 0.357922 negative regulationbiological_process of Notch signaling pathway 1 0.47% 0.049628 0.357922 protein ADP-ribosylationbiological_process 1 0.47% 0.054411 0.085336 positive regulation biological_processof protein secretion 1 0.47% 0.054411 0.386558 negative regulationbiological_process of extrinsic apoptotic signalin 1g pathway via 0.47% death domain 0.054411 receptors 0.386558 apoptotic mitochondrialbiological_process changes 1 0.47% 0.054411 0.386558 associative learning biological_process 1 0.47% 0.054411 0.386558 cartilage condensationbiological_process 1 0.47% 0.054411 0.386558 cell death biological_process 1 0.47% 0.054411 0.386558 release of sequesteredbiological_process calcium ion into cytosol 1 0.47% 0.054411 0.386558 cartilage developmentbiological_process 2 0.93% 0.055242 0.085374 response to heat biological_processDraft 1 0.47% 0.059371 0.412561 positive regulation biological_processof neuron apoptotic process 1 0.47% 0.059371 0.412561 regulation of heart biological_processrate by cardiac conduction 1 0.47% 0.059371 0.412561 cochlea morphogenesisbiological_process 1 0.47% 0.059371 0.412561 learning or memory biological_process 1 0.47% 0.064503 0.097938 lactation biological_process 1 0.47% 0.064503 0.43862 regulation of cell differentiationbiological_process 1 0.47% 0.069803 0.105647 triglyceride metabolicbiological_process process 1 0.47% 0.069803 0.471292 bone morphogenesisbiological_process 1 0.47% 0.069803 0.471292 one-carbon metabolicbiological_process process 1 0.47% 0.069803 0.471292 chromatin modificationbiological_process 1 0.47% 0.075265 0.113016 negative regulationbiological_process of endothelial cell proliferati 1on 0.47% 0.075265 0.504592 cellular response tobiological_process heat 1 0.47% 0.075265 0.504592 carbohydrate phosphorylationbiological_process 1 0.47% 0.075265 0.504592 neuromuscular junctionbiological_process development 1 0.47% 0.075265 0.504592 endoplasmic reticulumbiological_process unfolded protein response 1 0.47% 0.075265 0.504592 proximal/distal patternbiological_process formation 1 0.47% 0.075265 0.504592 cellular response tobiological_process interleukin-1 1 0.47% 0.075265 0.504592 carbohydrate metabolicbiological_process process 5 2.34% 0.076764 0.112777 cell cycle arrest biological_process 2 0.93% 0.079011 0.115899 mRNA export frombiological_process nucleus 1 0.47% 0.080884 0.523823 synaptic transmissionbiological_process 2 0.93% 0.082292 0.119788 sodium ion transportbiological_process 2 0.93% 0.082292 0.529336 heart development biological_process 4 1.87% 0.085095 0.123491 cellular response tobiological_process oxidative stress 1 0.47% 0.086657 0.125567 social behavior biological_process 1 0.47% 0.086657 0.549983 positive regulation biological_processof cell differentiation 1 0.47% 0.086657 0.549983

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inner ear morphogenesisbiological_process 2 0.93% 0.092538 0.133076 protein kinase B signalingbiological_process 1 0.47% 0.098643 0.605856 positive regulation biological_processof inflammatory response 1 0.47% 0.098643 0.605856 cellular response tobiological_process transforming growth factor 1beta stimulus 0.47% 0.098643 0.605856 response to drug biological_process 2 0.93% 0.099702 0.140202 brown fat cell differentiationbiological_process 1 0.47% 0.104847 0.635758 limb developmentbiological_process 1 0.47% 0.104847 0.635758 apoptotic signalingbiological_process pathway 1 0.47% 0.104847 0.635758 protein methylation biological_process 1 0.47% 0.104847 0.635758 peptidyl-threonine biological_processphosphorylation 1 0.47% 0.104847 0.635758 protein ubiquitinationbiological_process involved in ubiquitin-depend 1ent protein 0.47%catabolic 0.104847 process 0.635758 cell cycle biological_process 2 0.93% 0.110937 0.153953 negative regulationbiological_process of translation 1 0.47% 0.111186 0.665715 negative regulationbiological_process of ERK1 and ERK2 cascade 1 0.47% 0.111186 0.665715 Wnt signaling pathwaybiological_process 2 0.93% 0.11481 0.157719 midbrain developmentbiological_process 1 0.47% 0.117655 0.161162 negative regulationbiological_process of I-kappaB kinase/NF-kappaB 1 signaling 0.47% 0.117655 0.682975 negative regulationbiological_process of MAP kinase activity 1 0.47% 0.117655 0.682975 protein complex assemblybiological_process 1 0.47% 0.117655 0.682975 dephosphorylation biological_process 4 1.87% 0.117713 0.160319 patterning of bloodbiological_process vessels Draft 1 0.47% 0.124252 0.168741 positive regulation biological_processof cell-substrate adhesion 1 0.47% 0.124252 0.708309 embryonic forelimbbiological_process morphogenesis 1 0.47% 0.124252 0.708309 positive regulation biological_processof cell adhesion 1 0.47% 0.124252 0.708309 negative regulationbiological_process of fat cell differentiation 1 0.47% 0.13097 0.742166 regulation of proteinbiological_process phosphorylation 1 0.47% 0.13097 0.742166 protein oligomerizationbiological_process 1 0.47% 0.13097 0.742166 pigmentation biological_process 1 0.47% 0.13097 0.742166 protein localizationbiological_process to plasma membrane 1 0.47% 0.137808 0.184519 negative regulationbiological_process of BMP signaling pathway 1 0.47% 0.137808 0.77629 positive regulation biological_processof endothelial cell proliferati 1on 0.47% 0.14476 0.192743 fatty acid metabolicbiological_process process 1 0.47% 0.14476 0.810653 positive regulation biological_processof catalytic activity 1 0.47% 0.151822 0.845231 mitochondrion organizationbiological_process 1 0.47% 0.151822 0.845231 extrinsic apoptotic biological_processsignaling pathway 1 0.47% 0.151822 0.845231 negative regulationbiological_process of canonical Wnt signaling 2pathway 0.93% 0.152444 0.201006 neuron developmentbiological_process 1 0.47% 0.158991 0.20906 cellular response tobiological_process mechanical stimulus 1 0.47% 0.158991 0.869884 cellular response tobiological_process amino acid stimulus 1 0.47% 0.158991 0.869884 response to toxic substancebiological_process 1 0.47% 0.158991 0.869884 positive regulation biological_processof neuron projection developmen 1t 0.47% 0.158991 0.869884 negative regulationbiological_process of cell proliferation 5 2.34% 0.163056 0.212935 glucose homeostasisbiological_process 2 0.93% 0.166049 0.216249 regulation of RNA biological_processbiosynthetic process 1 0.47% 0.166264 0.216234 skeletal system morphogenesisbiological_process 1 0.47% 0.166264 0.889232 neural tube developmentbiological_process 1 0.47% 0.166264 0.889232 nucleobase-containingbiological_process compound metabolic process 1 0.47% 0.173636 0.224594

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cellular response tobiological_process tumor necrosis factor 1 0.47% 0.173636 0.923472 extracellular matrixbiological_process organization 2 0.93% 0.175397 0.225951 positive regulation biological_processof cell growth 1 0.47% 0.181104 0.942138 cellular response tobiological_process hypoxia 1 0.47% 0.181104 0.942138 dorsal/ventral patternbiological_process formation 1 0.47% 0.188665 0.976136 sperm motility biological_process 1 0.47% 0.188665 0.976136 multicellular organismalbiological_process development 4 1.87% 0.201339 0.255907 potassium ion transportbiological_process 2 0.93% 0.204717 0.258818 transcription, DNA-templatedbiological_process 1 0.47% 0.21596 0.272309 odontogenesis of dentin-containingbiological_process tooth 1 0.47% 0.22774 0.2849 cholesterol homeostasisbiological_process 1 0.47% 0.235787 0.294193 BMP signaling pathwaybiological_process 1 0.47% 0.243904 0.303129 regulation of gene expressionbiological_process 3 1.40% 0.246212 0.304408 anterior/posterior patternbiological_process specification 2 0.93% 0.251994 0.310749 negative regulationbiological_process of NF-kappaB transcription 1 factor activity 0.47% 0.252089 0.310464 skin development biological_process 1 0.47% 0.260337 0.318562 intracellular signal biological_processtransduction 5 2.34% 0.261257 0.318052 embryonic digit morphogenesisbiological_process 1 0.47% 0.268648 0.325385 embryonic limb morphogenesisbiological_process 1 0.47% 0.277016 0.3334 regulation of transcription,biological_process DNA-templated 8 3.74% 0.281478 0.33749 sodium ion transmembranebiological_process transport Draft 1 0.47% 0.285441 0.340954 positive regulation biological_processof peptidyl-serine phosphorylat 1ion 0.47% 0.311026 0.369198 positive regulation biological_processof gene expression 3 1.40% 0.31248 0.370001 protein localization biological_process 1 0.47% 0.328316 0.387787 positive regulation biological_processof cell proliferation 1 0.47% 0.333106 0.392472 protein transport biological_process 1 0.47% 0.336269 0.395708 transmembrane receptorbiological_process protein tyrosine kinase 1 signaling pathway 0.47% 0.337023 0.396106 peptidyl-serine phosphorylationbiological_process 1 0.47% 0.345769 0.405385 protein homooligomerizationbiological_process 2 0.93% 0.350273 0.409655 cellular response tobiological_process lipopolysaccharide 1 0.47% 0.354552 0.414151 negative regulationbiological_process of cell migration 1 0.47% 0.363369 0.422894 cell redox homeostasisbiological_process 1 0.47% 0.372217 0.43056 phosphorylation biological_process 5 2.34% 0.37411 0.431178 MAPK cascade biological_process 1 0.47% 0.381096 0.438698 oxidation-reductionbiological_process process 10 4.67% 0.386936 0.444883 response to lipopolysaccharidebiological_process 1 0.47% 0.390003 0.447868 ATP catabolic processbiological_process 4 1.87% 0.392906 0.449575 neuron projection developmentbiological_process 1 0.47% 0.398935 0.455926 protein stabilizationbiological_process 1 0.47% 0.407891 0.464488 proteolysis biological_process 4 1.87% 0.413124 0.468765 positive regulation biological_processof angiogenesis 1 0.47% 0.416869 0.472452 proteasome-mediatedbiological_process ubiquitin-dependent protein 1 catabolic process 0.47% 0.425867 0.481503 regulation of Rho proteinbiological_process signal transduction 1 0.47% 0.434883 0.490532 response to oxidativebiological_process stress 1 0.47% 0.443916 0.498358 GTP catabolic processbiological_process 1 0.47% 0.448685 0.501936 cell adhesion biological_process 1 0.47% 0.452808 0.505954 regulation of cell shapebiological_process 1 0.47% 0.462023 0.515042

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positive regulation biological_processof sequence-specific DNA bindin 1g transcription 0.47% factor 0.498357 activity 0.545957 nervous system developmentbiological_process 1 0.47% 0.507457 0.555286 post-embryonic developmentbiological_process 1 0.47% 0.51656 0.563305 in utero embryonicbiological_process development 3 1.40% 0.551765 0.596232 positive regulation biological_processof NF-kappaB transcription 1factor activity 0.47% 0.552976 0.596863 positive regulation biological_processof transcription, DNA-templated 6 2.80% 0.560843 0.604669 positive regulation biological_processof protein phosphorylation 1 0.47% 0.589335 0.631809 negative regulationbiological_process of gene expression 1 0.47% 0.598406 0.640813 protein phosphorylationbiological_process 5 2.34% 0.601912 0.643843 negative regulationbiological_process of transcription, DNA-templated 5 2.34% 0.610502 0.650838 positive regulation biological_processof ERK1 and ERK2 cascade 1 0.47% 0.625557 0.666141 potassium ion transmembranebiological_process transport 1 0.47% 0.65259 0.691832 metabolic processbiological_process 13 6.07% 0.663166 0.700703 axon guidance biological_process 1 0.47% 0.688404 0.724957 regulation of transcriptionbiological_process from RNA polymerase 1 II promoter 0.47% 0.698808 0.734288 inflammatory responsebiological_process 1 0.47% 0.732721 0.766539 apoptotic process biological_process 1 0.47% 0.741516 0.774038 regulation of cell proliferationbiological_process 1 0.47% 0.827996 0.855865 cation transport biological_process 1 0.47% 0.853363 0.877323 protein autophosphorylationbiological_process 1 0.47% 0.870112 0.892615 cellular response tobiological_process DNA damage stimulus Draft 1 0.47% 0.874802 0.895497 transcription from RNAbiological_process polymerase II promoter 1 0.47% 0.903436 0.919862 negative regulationbiological_process of apoptotic process 3 1.40% 0.919625 0.933351 lipid metabolic processbiological_process 1 0.47% 0.943784 0.955832 positive regulation biological_processof transcription from RNA polym 8erase II promoter 3.74% 0.947416 0.958491 negative regulationbiological_process of transcription from RNA 5polymerase II promoter 2.34% 0.965616 0.972768 transmembrane transportbiological_process 5 2.34% 0.976164 0.981318 The significant GO terms of down-regulated genes calcium ion bindingmolecular_function 1 0.47% 7.27E-07 2.77E-05 oxygen binding molecular_function 1 0.47% 5.60E-05 0.001089 oxygen transporter molecular_functionactivity 1 0.47% 0.00057 0.0092 phospholipase A2 activitymolecular_function 1 0.47% 0.075265 0.504592 ion channel activity molecular_function 1 0.47% 0.122531 0.166643 metal ion binding molecular_function 1 0.47% 0.176895 0.227574 heme binding molecular_function 1 0.47% 0.254674 0.312435 phospholipid bindingmolecular_function 1 0.47% 0.29392 0.350641 structural moleculemolecular_function activity 1 0.47% 0.602338 0.643575 structural constituentmolecular_function of ribosome 1 0.47% 0.861051 0.884272 membrane cellular_component 1 0.47% 0.000902 0.004852 hemoglobin complexcellular_component 1 0.47% 0.006097 0.063787 extracellular region cellular_component 1 0.47% 0.091765 0.132164 intermediate filamentcellular_component 1 0.47% 0.235823 0.293468 endoplasmic reticulumcellular_component 1 0.47% 0.263979 0.320545 mitochondrion cellular_component 1 0.47% 0.283654 0.339671 ribonucleoprotein complexcellular_component 1 0.47% 0.494458 0.542309 extracellular vesicularcellular_component exosome 1 0.47% 0.678786 0.715619 extracellular space cellular_component 1 0.47% 0.696067 0.732217

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ribosome cellular_component 1 0.47% 0.843777 0.868406 intracellular cellular_component 1 0.47% 0.877442 0.897234 oxygen transport biological_process 1 0.47% 0.000753 0.011951 phosphatidic acid metabolicbiological_process process 1 0.47% 0.0009 0.014048 phospholipid metabolicbiological_process process 1 0.47% 0.104847 0.147218 lipid catabolic processbiological_process 1 0.47% 0.166264 0.889232 ion transport biological_process 1 0.47% 0.258125 0.316261 transport biological_process 1 0.47% 0.569678 0.612806 ion transmembranebiological_process transport 1 0.47% 0.955112 0.964228 translation biological_process 1 0.47% 0.969733 0.975883

Draft

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Supplemental Table S4. The significant KEGG ways of differentially expressed genes Pathway_ID Psthway_DES Diff_gene_in_this_pathwayP-value ocu04260 Cardiac muscle contraction - Oryctolagus cuniculus15 (rabbit) 3.56E-15 ocu05414 Dilated cardiomyopathy - Oryctolagus cuniculus (rabbit)11 2.65E-10 ocu05410 Hypertrophic cardiomyopathy (HCM) - Oryctolagus11 cuniculus (rabbit) 2.65E-10 ocu04261 Adrenergic signaling in cardiomyocytes - Oryctolagus12 cuniculus 9.80E-09 (rabbit) ocu05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)7 - Oryctolagus 2.05E-06 cuniculus (rabbit) ocu04530 Tight junction - Oryctolagus cuniculus (rabbit) 9 4.86E-06 ocu00010 Glycolysis / Gluconeogenesis - Oryctolagus cuniculus5 (rabbit) 0.000166851 ocu00030 Pentose phosphate pathway - Oryctolagus cuniculus3 (rabbit) 0.000447537 ocu05010 Alzheimer's disease - Oryctolagus cuniculus (rabbit)7 0.000987367 ocu01230 Biosynthesis of amino acids - Oryctolagus cuniculus4 (rabbit) 0.001699944 ocu00190 Oxidative phosphorylation - Oryctolagus cuniculus 6(rabbit) 0.001998665 ocu04932 Non-alcoholic fatty liver disease (NAFLD) - Oryctolagus6 cuniculus 0.003248325 (rabbit) ocu05012 Parkinson's disease - Oryctolagus cuniculus (rabbit)6 0.003558092 ocu00500 Starch and sucrose metabolism - Oryctolagus cuniculus3 (rabbit) 0.009055494 ocu00052 Galactose metabolism - Oryctolagus cuniculus (rabbit)2 0.011199545 ocu00051 Fructose and mannose metabolism - Oryctolagus cuniculus2 (rabbit) 0.012414351 ocu04810 Regulation of actin cytoskeleton - Oryctolagus cuniculus6 (rabbit) 0.013128566 ocu01200 Carbon metabolism - Oryctolagus cuniculus (rabbit)4 0.014205948 ocu04020 Calcium signaling pathway - OryctolagusDraft cuniculus5 (rabbit) 0.014827989 ocu04670 Leukocyte transendothelial migration - Oryctolagus4 cuniculus 0.017799147 (rabbit) ocu00230 Purine metabolism - Oryctolagus cuniculus (rabbit) 5 0.019083082 ocu04973 Carbohydrate digestion and absorption - Oryctolagus2 cuniculus 0.02131934 (rabbit) ocu04910 Insulin signaling pathway - Oryctolagus cuniculus (rabbit)4 0.021970257 ocu00910 Nitrogen metabolism - Oryctolagus cuniculus (rabbit)1 0.02727234 ocu00520 Amino sugar and nucleotide sugar metabolism - Oryctolagus2 0.030940473 cuniculus (rabbit) ocu05016 Huntington's disease - Oryctolagus cuniculus (rabbit)5 0.031910867 ocu04921 Oxytocin signaling pathway - Oryctolagus cuniculus4 (rabbit) 0.032195899 ocu05230 Central carbon metabolism in cancer - Oryctolagus cuniculus2 0.045206613 (rabbit) ocu04964 Proximal tubule bicarbonate reclamation - Oryctolagus1 cuniculus 0.060614202 (rabbit) ocu04710 Circadian rhythm - Oryctolagus cuniculus (rabbit) 1 0.060614202 ocu05143 African trypanosomiasis - Oryctolagus cuniculus (rabbit)1 0.060614202 ocu04911 Insulin secretion - Oryctolagus cuniculus (rabbit) 2 0.065617615 ocu04520 Adherens junction - Oryctolagus cuniculus (rabbit) 2 0.068861179 ocu05416 Viral myocarditis - Oryctolagus cuniculus (rabbit) 2 0.068861179 ocu00250 Alanine, aspartate and glutamate metabolism - Oryctolagus1 cuniculus 0.078044067 (rabbit) ocu04510 Focal adhesion - Oryctolagus cuniculus (rabbit) 4 0.088474661 ocu00592 alpha-Linolenic acid metabolism - Oryctolagus cuniculus1 (rabbit) 0.090581016 ocu01100 Metabolic pathways - Oryctolagus cuniculus (rabbit)19 0.095991746 ocu05030 Cocaine addiction - Oryctolagus cuniculus (rabbit) 1 0.117642046 ocu03018 RNA degradation - Oryctolagus cuniculus (rabbit) 2 0.122516892 ocu00591 Linoleic acid metabolism - Oryctolagus cuniculus (rabbit)1 0.124788535 ocu04130 SNARE interactions in vesicular transport - Oryctolagus1 cuniculus 0.124788535 (rabbit) ocu04960 Aldosterone-regulated sodium reabsorption - Oryctolagus1 cuniculus 0.124788535 (rabbit) ocu05146 Amoebiasis - Oryctolagus cuniculus (rabbit) 2 0.131379983 ocu04961 Endocrine and other factor-regulated calcium reabsorption1 - 0.132076782Oryctolagus cuniculus (rabbit)

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ocu04022 cGMP-PKG signaling pathway - Oryctolagus cuniculus3 (rabbit) 0.156256042 ocu04978 Mineral absorption - Oryctolagus cuniculus (rabbit)1 0.162545891 ocu05144 Malaria - Oryctolagus cuniculus (rabbit) 1 0.162545891 ocu00565 Ether lipid metabolism - Oryctolagus cuniculus (rabbit)1 0.162545891 ocu04919 Thyroid hormone signaling pathway - Oryctolagus cuniculus2 0.164570882 (rabbit) ocu00260 Glycine, serine and threonine metabolism - Oryctolagus1 cuniculus 0.170467826 (rabbit) ocu05031 Amphetamine addiction - Oryctolagus cuniculus (rabbit)1 0.194890728 ocu04270 Vascular smooth muscle contraction - Oryctolagus cuniculus2 (rabbit) 0.21735379 ocu00330 Arginine and proline metabolism - Oryctolagus cuniculus1 (rabbit) 0.220208034 ocu05200 Pathways in cancer - Oryctolagus cuniculus (rabbit)1 0.225936733 ocu04024 cAMP signaling pathway - Oryctolagus cuniculus (rabbit)3 0.228819775 ocu00480 Glutathione metabolism - Oryctolagus cuniculus (rabbit)1 0.22882654 ocu04972 Pancreatic secretion - Oryctolagus cuniculus (rabbit)2 0.234295503 ocu04150 mTOR signaling pathway - Oryctolagus cuniculus (rabbit)1 0.237528154 ocu04152 AMPK signaling pathway - Oryctolagus cuniculus (rabbit)2 0.251700543 ocu04918 Thyroid hormone synthesis - Oryctolagus cuniculus1 (rabbit) 0.264093914 ocu04975 Fat digestion and absorption - Oryctolagus cuniculus1 (rabbit) 0.273090668 ocu04970 Salivary secretion - Oryctolagus cuniculus (rabbit) 1 0.282152319 ocu04920 Adipocytokine signaling pathway - Oryctolagus cuniculus1 (rabbit) 0.282152319 ocu05203 Viral carcinogenesis - Oryctolagus cuniculus (rabbit)3 0.318026547 ocu04610 Complement and coagulation cascadesDraft - Oryctolagus1 cuniculus 0.318981344 (rabbit) ocu04727 GABAergic synapse - Oryctolagus cuniculus (rabbit)1 0.328318261 ocu04971 Gastric acid secretion - Oryctolagus cuniculus (rabbit)1 0.328318261 ocu04666 Fc gamma R-mediated phagocytosis - Oryctolagus cuniculus1 0.337700932 (rabbit) ocu04912 GnRH signaling pathway - Oryctolagus cuniculus (rabbit)1 0.337700932 ocu05322 Systemic lupus erythematosus - Oryctolagus cuniculus2 (rabbit) 0.344730197 ocu04976 Bile secretion - Oryctolagus cuniculus (rabbit) 1 0.347126434 ocu05202 Transcriptional misregulation in cancer - Oryctolagus2 cuniculus 0.364349808 (rabbit) ocu00830 Retinol metabolism - Oryctolagus cuniculus (rabbit)1 0.366094586 ocu00982 Drug metabolism - cytochrome P450 - Oryctolagus 1cuniculus 0.375631739 (rabbit) ocu04010 MAPK signaling pathway - Oryctolagus cuniculus (rabbit)3 0.3850554 ocu05100 Bacterial invasion of epithelial cells - Oryctolagus cuniculus1 0.385200727(rabbit) ocu04723 Retrograde endocannabinoid signaling - Oryctolagus1 cuniculus 0.423744385 (rabbit) ocu00564 Glycerophospholipid metabolism - Oryctolagus cuniculus1 (rabbit) 0.423744385 ocu04725 Cholinergic synapse - Oryctolagus cuniculus (rabbit)1 0.45286629 ocu04750 Inflammatory mediator regulation of TRP channels 1- Oryctolagus 0.462602359 cuniculus (rabbit) ocu00980 Metabolism of xenobiotics by cytochrome P450 - Oryctolagus1 0.462602359 cuniculus (rabbit) ocu00590 Arachidonic acid metabolism - Oryctolagus cuniculus1 (rabbit) 0.491867507 ocu05034 Alcoholism - Oryctolagus cuniculus (rabbit) 2 0.501029077 ocu04726 Serotonergic synapse - Oryctolagus cuniculus (rabbit)1 0.501634911 ocu04080 Neuroactive ligand-receptor interaction - Oryctolagus1 cuniculus 0.503896619 (rabbit) ocu05204 Chemical carcinogenesis - Oryctolagus cuniculus (rabbit)1 0.511405311 ocu04066 HIF-1 signaling pathway - Oryctolagus cuniculus (rabbit)1 0.521176874 ocu04974 Protein digestion and absorption - Oryctolagus cuniculus1 (rabbit) 0.530947818 ocu04380 Osteoclast differentiation - Oryctolagus cuniculus (rabbit)1 0.60889469 ocu04068 FoxO signaling pathway - Oryctolagus cuniculus (rabbit)1 0.695451841 ocu04014 Ras signaling pathway - Oryctolagus cuniculus (rabbit)1 0.760984529

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ocu04310 Wnt signaling pathway - Oryctolagus cuniculus (rabbit)1 0.761405315 ocu05206 MicroRNAs in cancer - Oryctolagus cuniculus (rabbit)1 0.789212204 ocu05205 Proteoglycans in cancer - Oryctolagus cuniculus (rabbit)1 0.823493904 ocu03010 Ribosome - Oryctolagus cuniculus (rabbit) 2 0.874720636 ocu05169 Epstein-Barr virus infection - Oryctolagus cuniculus1 (rabbit) 0.874782983 ocu04141 Protein processing in endoplasmic reticulum - Oryctolagus1 cuniculus 0.897194096 (rabbit)

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Supplemental Table S4. The significant KEGG ways of differentially expressed genes FDR 3.49E-13 1.30E-08 1.30E-08 2.40E-07 4.02E-05 7.93E-05 0.002335911 0.005482328 0.010751325 0.016659452 0.017806285 0.026527991 0.026822537 0.063388458 0.073170363 0.076037902 0.075682321 0.077343492 0.076481208 Draft 0.087215819 0.089054384 0.094967968 0.0936124 0.111362055 0.121286654 0.120279422 0.116859191 0.158223144 0.204834199 0.212149707 0.212149707 0.200953946 0.204496834 0.224946517 0.218523388 0.24084769 0.239917285 0.247557662 0.295613346 0.300166385 0.298275035 0.330520985 0.330520985 0.292619053 0.28763388

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0.332893307 0.338925476 0.388524326 0.388524326 0.322558928 0.327565627 0.367294064 0.401899461 0.399636803 0.402578178 0.400434606 0.393421069 0.395878608 0.39453829 0.411110887 0.424282025 0.431659443 0.438903608 0.502744133 0.479486179 0.473638965 Draft 0.480226709 0.554744647 0.479633208 0.560926972 0.475824778 0.472477647 0.48912714 0.484827965 0.490825473 0.496518805 0.490255471 0.532396792 0.61980522 0.554761206 0.559691743 0.657029437 0.580759225 0.584533924 0.578355545 0.574207775 0.576065753 0.580401519 0.58463917 0.663018662 0.748948136 0.810613955

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0.802341085 0.822795702 0.849498975 0.892943982 0.883801365 0.897194096

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