First Report of Caprine Abortions Due to Chlamydia Abortus in Argentina
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
Aus Dem Institut Für Molekulare Pathogenese Des Friedrich - Loeffler - Instituts, Bundesforschungsinstitut Für Tiergesundheit, Standort Jena
Aus dem Institut für molekulare Pathogenese des Friedrich - Loeffler - Instituts, Bundesforschungsinstitut für Tiergesundheit, Standort Jena eingereicht über das Institut für Veterinär - Physiologie des Fachbereichs Veterinärmedizin der Freien Universität Berlin Evaluation and pathophysiological characterisation of a bovine model of respiratory Chlamydia psittaci infection Inaugural - Dissertation zur Erlangung des Grades eines Doctor of Philosophy (PhD) an der Freien Universität Berlin vorgelegt von Carola Heike Ostermann Tierärztin aus Berlin Berlin 2013 Journal-Nr.: 3683 Gedruckt mit Genehmigung des Fachbereichs Veterinärmedizin der Freien Universität Berlin Dekan: Univ.-Prof. Dr. Jürgen Zentek Erster Gutachter: Prof. Dr. Petra Reinhold, PhD Zweiter Gutachter: Univ.-Prof. Dr. Kerstin E. Müller Dritter Gutachter: Univ.-Prof. Dr. Lothar H. Wieler Deskriptoren (nach CAB-Thesaurus): Chlamydophila psittaci, animal models, physiopathology, calves, cattle diseases, zoonoses, respiratory diseases, lung function, lung ventilation, blood gases, impedance, acid base disorders, transmission, excretion Tag der Promotion: 30.06.2014 Bibliografische Information der Deutschen Nationalbibliothek Die Deutsche Nationalbibliothek verzeichnet diese Publikation in der Deutschen Nationalbibliografie; detaillierte bibliografische Daten sind im Internet über <http://dnb.ddb.de> abrufbar. ISBN: 978-3-86387-587-9 Zugl.: Berlin, Freie Univ., Diss., 2013 Dissertation, Freie Universität Berlin D 188 Dieses Werk ist urheberrechtlich geschützt. Alle Rechte, auch -
Platypus Collins, L.R
AUSTRALIAN MAMMALS BIOLOGY AND CAPTIVE MANAGEMENT Stephen Jackson © CSIRO 2003 All rights reserved. Except under the conditions described in the Australian Copyright Act 1968 and subsequent amendments, no part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, duplicating or otherwise, without the prior permission of the copyright owner. Contact CSIRO PUBLISHING for all permission requests. National Library of Australia Cataloguing-in-Publication entry Jackson, Stephen M. Australian mammals: Biology and captive management Bibliography. ISBN 0 643 06635 7. 1. Mammals – Australia. 2. Captive mammals. I. Title. 599.0994 Available from CSIRO PUBLISHING 150 Oxford Street (PO Box 1139) Collingwood VIC 3066 Australia Telephone: +61 3 9662 7666 Local call: 1300 788 000 (Australia only) Fax: +61 3 9662 7555 Email: [email protected] Web site: www.publish.csiro.au Cover photos courtesy Stephen Jackson, Esther Beaton and Nick Alexander Set in Minion and Optima Cover and text design by James Kelly Typeset by Desktop Concepts Pty Ltd Printed in Australia by Ligare REFERENCES reserved. Chapter 1 – Platypus Collins, L.R. (1973) Monotremes and Marsupials: A Reference for Zoological Institutions. Smithsonian Institution Press, rights Austin, M.A. (1997) A Practical Guide to the Successful Washington. All Handrearing of Tasmanian Marsupials. Regal Publications, Collins, G.H., Whittington, R.J. & Canfield, P.J. (1986) Melbourne. Theileria ornithorhynchi Mackerras, 1959 in the platypus, 2003. Beaven, M. (1997) Hand rearing of a juvenile platypus. Ornithorhynchus anatinus (Shaw). Journal of Wildlife Proceedings of the ASZK/ARAZPA Conference. 16–20 March. -
By Emaan M. Khan a THESIS Submitted to Oregon State University Honors College in Partial Fulfillment of the Requirements For
Polymorphic Membrane Protein-13G Expression Variation Demonstrated between Chlamydia abortus Culture Conditions and Strains by Emaan M. Khan A THESIS submitted to Oregon State University Honors College in partial fulfillment of the requirements for the degree of Honors Baccalaureate of Science in Microbiology (Honors Associate) Presented May 18, 2017 Commencement June 2017 AN ABSTRACT OF THE THESIS OF Emaan Khan for the degree of Honors Baccalaureate of Science in Microbiology presented on May 18, 2017. Title: Polymorphic Membrane Protein-13G Expression Variation Demonstrated between Chlamydia abortus Culture Conditions and Strains Abstract approved: _____________________________________________________ Daniel Rockey Chlamydiae encode a family of proteins named the polymorphic membrane proteins, or Pmps, whose role in infection and pathogenesis is unclear. The Rockey Laboratory is studying polymorphic membrane protein expression in Chlamydia abortus, a zoonotic pathogen that causes abortions in ewes. C. abortus contains 18 pmp genes, some of which carry internal homopolymeric repeat sequences (poly-G) that may have a role in controlling protein expression within infected cells. The goal of this project was to elucidate the role of Pmps in the pathogenesis of C. abortus by evaluating patterns of Pmp expression and of the length of a poly-G region within pmp13G. Previous research in the Rockey Laboratory showed a variation in Pmp13G expression and suggested that expression of the pmp13G gene is required under certain culture conditions and not in others. It was hypothesized that this variation was due to changes in culture conditions and may have been linked to the necessity of the pmp13G gene only under certain stages of growth or certain culture conditions. -
In Vitro Analysis of Genetically Distinct Chlamydia Pecorum Isolates Reveals Key Growth Differences in Mammalian Epithelial and Immune Cells T ⁎ Md
Veterinary Microbiology 232 (2019) 22–29 Contents lists available at ScienceDirect Veterinary Microbiology journal homepage: www.elsevier.com/locate/vetmic In vitro analysis of genetically distinct Chlamydia pecorum isolates reveals key growth differences in mammalian epithelial and immune cells T ⁎ Md. Mominul Islama, , Martina Jelocnika, Susan Ansteya, Bernhard Kaltenboeckb, Nicole Borelc, Peter Timmsa, Adam Polkinghorned a Genecology Research Centre, Faculty of Science, Health, Education and Engineering, University of the Sunshine Coast, Sippy Downs, Australia b Department of Pathobiology, Auburn University, Auburn, USA c Institute of Veterinary Pathology, University of Zurich, Switzerland d Animal Research Centre, Faculty of Science, Health, Education and Engineering, University of the Sunshine Coast, Sippy Downs, Australia ARTICLE INFO ABSTRACT Keywords: Chlamydia (C.) pecorum is an obligate intracellular bacterium that infects and causes disease in a broad range of Chlamydia pecorum animal hosts. Molecular studies have revealed that this pathogen is genetically diverse with certain isolates In vitro growth linked to different disease outcomes. Limited in vitro or in vivo data exist to support these observations, further Genetically distinct hampering efforts to improve our understanding of C. pecorum pathogenesis. In this study, we evaluated whether Developmental cycle genetically distinct C. pecorum isolates (IPA, E58, 1710S, W73, JP-1-751) display different in vitro growth phenotypes in different mammalian epithelial and immune cells. In McCoy cells, shorter lag phases were ob- served for W73 and JP-1-751 isolates. Significantly smaller inclusions were observed for the naturally plasmid- free E58 isolate. C. pecorum isolates of bovine (E58) and ovine origin (IPA, W73, JP-1-751) grew faster in bovine cells compared to a porcine isolate (1710S). -
CHLAMYDIOSIS (Psittacosis, Ornithosis)
EAZWV Transmissible Disease Fact Sheet Sheet No. 77 CHLAMYDIOSIS (Psittacosis, ornithosis) ANIMAL TRANS- CLINICAL FATAL TREATMENT PREVENTION GROUP MISSION SIGNS DISEASE ? & CONTROL AFFECTED Birds Aerogenous by Very species Especially the Antibiotics, Depending on Amphibians secretions and dependent: Chlamydophila especially strain. Reptiles excretions, Anorexia psittaci is tetracycline Mammals Dust of Apathy ZOONOSIS. and In houses People feathers and Dispnoe Other strains doxycycline. Maximum of faeces, Diarrhoea relative host For hygiene in Oral, Cachexy specific. substitution keeping and Direct Conjunctivitis electrolytes at feeding. horizontal, Rhinorrhea Yes: persisting Vertical, Nervous especially in diarrhoea. in zoos By parasites symptoms young animals avoid stress, (but not on the Reduced and animals, quarantine, surface) hatching rates which are blood screening, Increased new- damaged in any serology, born mortality kind. However, take swabs many animals (throat, cloaca, are carrier conjunctiva), without clinical IFT, PCR. symptoms. Fact sheet compiled by Last update Werner Tschirch, Veterinary Department, March 2002 Hoyerswerda, Germany Fact sheet reviewed by E. F. Kaleta, Institution for Poultry Diseases, Justus-Liebig-University Gießen, Germany G. M. Dorrestein, Dept. Pathology, Utrecht University, The Netherlands Susceptible animal groups In case of Chlamydophila psittaci: birds of every age; up to now proved in 376 species of birds of 29 birds orders, including 133 species of parrots; probably all of the about 9000 species of birds are susceptible for the infection; for the outbreak of the disease, additional factors are necessary; very often latent infection in captive as well as free-living birds. Other susceptible groups are amphibians, reptiles, many domestic and wild mammals as well as humans. The other Chlamydia sp. -
Psittacosis/ Avian Chlamydiosis
Psittacosis/ Importance Avian chlamydiosis, which is also called psittacosis in some hosts, is a bacterial Avian disease of birds caused by members of the genus Chlamydia. Chlamydia psittaci has been the primary organism identified in clinical cases, to date, but at least two Chlamydiosis additional species, C. avium and C. gallinacea, have now been recognized. C. psittaci is known to infect more than 400 avian species. Important hosts among domesticated Ornithosis, birds include psittacines, poultry and pigeons, but outbreaks have also been Parrot Fever documented in many other species, such as ratites, peacocks and game birds. Some individual birds carry C. psittaci asymptomatically. Others become mildly to severely ill, either immediately or after they have been stressed. Significant economic losses Last Updated: April 2017 are possible in commercial turkey flocks even when mortality is not high. Outbreaks have been reported occasionally in wild birds, and some of these outbreaks have been linked to zoonotic transmission. C. psittaci can affect mammals, including humans, that have been exposed to birds or contaminated environments. Some infections in people are subclinical; others result in mild to severe illnesses, which can be life-threatening. Clinical cases in pregnant women may be especially severe, and can result in the death of the fetus. Recent studies suggest that infections with C. psittaci may be underdiagnosed in some populations, such as poultry workers. There are also reports suggesting that it may occasionally cause reproductive losses, ocular disease or respiratory illnesses in ruminants, horses and pets. C. avium and C. gallinacea are still poorly understood. C. avium has been found in asymptomatic pigeons, which seem to be its major host, and in sick pigeons and psittacines. -
Seroprevalence and Risk Factors Associated with Chlamydia Abortus Infection in Sheep and Goats in Eastern Saudi Arabia
pathogens Article Seroprevalence and Risk Factors Associated with Chlamydia abortus Infection in Sheep and Goats in Eastern Saudi Arabia Mahmoud Fayez 1,2,† , Ahmed Elmoslemany 3,† , Mohammed Alorabi 4, Mohamed Alkafafy 4 , Ibrahim Qasim 5, Theeb Al-Marri 1 and Ibrahim Elsohaby 6,7,*,† 1 Al-Ahsa Veterinary Diagnostic Lab, Ministry of Environment, Water and Agriculture, Al-Ahsa 31982, Saudi Arabia; [email protected] (M.F.); [email protected] (T.A.-M.) 2 Department of Bacteriology, Veterinary Serum and Vaccine Research Institute, Ministry of Agriculture, Cairo 131, Egypt 3 Hygiene and Preventive Medicine Department, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafr El-Sheikh 33516, Egypt; [email protected] 4 Department of Biotechnology, College of Science, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia; [email protected] (M.A.); [email protected] (M.A.) 5 Department of Animal Resources, Ministry of Environment, Water and Agriculture, Riyadh 12629, Saudi Arabia; [email protected] 6 Department of Animal Medicine, Faculty of Veterinary Medicine, Zagazig University, Zagazig City 44511, Egypt 7 Department of Health Management, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, PE C1A 4P3, Canada * Correspondence: [email protected]; Tel.: +1-902-566-6063 † These authors contributed equally to this work. Citation: Fayez, M.; Elmoslemany, Abstract: Chlamydia abortus (C. abortus) is intracellular, Gram-negative bacterium that cause enzootic A.; Alorabi, M.; Alkafafy, M.; Qasim, abortion in sheep and goats. Information on C. abortus seroprevalence and flock management risk I.; Al-Marri, T.; Elsohaby, I. factors associated with C. abortus seropositivity in sheep and goats in Saudi Arabia are scarce. -
Efficacy of Two Chlamydia Abortus Subcellular Vaccines in a Pregnant Ewe Challenge Model for Ovine Enzootic Abortion
Article Efficacy of Two Chlamydia abortus Subcellular Vaccines in a Pregnant Ewe Challenge Model for Ovine Enzootic Abortion Morag Livingstone 1, Sean Ranjan Wattegedera 1 , Javier Palarea-Albaladejo 2,† , Kevin Aitchison 1, Cecilia Corbett 1,‡, Michelle Sait 1,§, Kim Wilson 1,k, Francesca Chianini 1 , Mara Silvia Rocchi 1 , Nicholas Wheelhouse 1,¶ , Gary Entrican 1,** and David Longbottom 1,* 1 Moredun Research Institute, Pentlands Science Park, Midlothian EH26 0PZ, UK; [email protected] (M.L.); [email protected] (S.R.W.); [email protected] (K.A.); [email protected] (C.C.); [email protected] (M.S.); [email protected] (K.W.); [email protected] (F.C.); [email protected] (M.S.R.); [email protected] (N.W.); [email protected] (G.E.) 2 Biomathematics and Statistics Scotland, Edinburgh EH9 3FD, UK; [email protected] * Correspondence: [email protected] † Current address: Department of Computer Science, Applied Mathematics and Statistics, University of Girona, 17003 Girona, Spain. ‡ Current address: Animal Plant and Health Agency Veterinary Investigation Centre, Thirsk YO7 1PZ, UK. § Current address: Microbiological Diagnostic Unit, Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Victoria 3010, Australia. Citation: Livingstone, M.; k Current address: Institute of Immunology and Infection Research, University of Edinburgh, Wattegedera, S.R.; Edinburgh EH9 3FL, UK. Palarea-Albaladejo, J.; Aitchison, K.; ¶ Current address: School of Applied Sciences, Edinburgh Napier University, Edinburgh EH11 4BN, UK. Corbett, C.; Sait, M.; Wilson, K.; ** Current address: The Roslin Institute, The University of Edinburgh, Easter Bush Campus, Midlothian EH25 9RG, UK. -
Seroprevalence of Antibodies to Chlamydophila Abortus Shown in Awassi Sheep and Local Goats in Jordan
Original Paper Vet. Med. – Czech, 49, 2004 (12): 460–466 Seroprevalence of antibodies to Chlamydophila abortus shown in Awassi sheep and local goats in Jordan K. M. A�-Q����1, L. A. S�����2, R. Y. R����3, N. Q. H�����2, F. M. A�-D���4 1Department of Veterinary Clinical Sciences, 2Department of Pathology and Animal Health, Faculty of Veterinary Medicine, Jordan University of Science and Technology, Irbid, Jordan 3Faculty of Veterinary Medicine, Cairo University, Gizza, Egypt 4Department of Animal Health, Ministry of Agriculture, Amman, Jordan ABSTRACT: A cold complement fixation test (CFT) was used to identify C. abortus infection in ewes and does in northern Jordan. Sera from 36 flocks of sheep and 20 flocks of goats were collected randomly. The results showed that 433 (21.8%) out of 1 984 ovine sera, and 82 (11.4%) out of 721 caprine sera, were seropositive for C. abortus infec- tion, as indicated by a titre ≥ 1:40. However, all the tested sheep flocks and goat flocks (100%) revealed at least one seropositive animal. There was a strong association (P < 0.05) between the rate of C. abortus infection and the size of the sheep flock, when larger flocks had higher infection rates. However, in goats, the flock size had no relation- ship with seropositivity. Age had no significant (P > 0.05) impact on C. abortus seropositivity. In sheep, there was a significant difference (P < 0.05) between the rates of the chlamydial infection in the four studied areas of northern Jordan. The highest infection rate in sheep (31.2%) was recorded in Mafraq area, while the rates in Irbid, Ajloun and Jerash were 18.5%, 11.2% and 13.9%, respectively. -
Title Pathogenesis of Chlamydial Infections( 本文(FULLTEXT) )
Title Pathogenesis of Chlamydial Infections( 本文(FULLTEXT) ) Author(s) RAJESH, CHAHOTA Report No.(Doctoral Degree) 博士(獣医学) 甲第226号 Issue Date 2007-03-13 Type 博士論文 Version author URL http://hdl.handle.net/20.500.12099/21409 ※この資料の著作権は、各資料の著者・学協会・出版社等に帰属します。 Pathogenesis of Chlamydial Infections !"#$%&'()*+%,-./0 2006 The United Graduate School of Veterinary Sciences, Gifu University, (Gifu University) RAJESH CHAHOTA Pathogenesis of Chlamydial Infections !"#$%&'()*+%,-./0 RAJESH CHAHOTA CONTENTS PREFACE……………………………………………………………………… 1 PART I Molecular Epidemiology, Genetic Diversity, Phylogeny and Virulence Analysis of Chlamydophila psittaci CHAPTER I: Study of molecular epizootiology of Chlamydophila psittaci among captive and feral avian species on the basis of VD2 region of ompA gene Introduction……………………………………………………………… 7 Materials and Methods…………………………………………………... 9 Results…………………………………………………………………… 16 Discussion……………………………………………………………….. 31 Summary……………………………………………………………….... 35 CHAPTER II: Analysis of genetic diversity and molecular phylogeny of the Chlamydophila psittaci strains prevalent among avian fauna and those associated with human psittacosis Introduction……………………………………………………………… 36 Materials and Methods…………………………………………………... 38 Results…………………………………………………………………… 42 Discussion……………………………………………………………….. 55 Summary………………………………………………………………… 59 CHAPTER III: Examination of virulence patterns of the Chlamydophila psittaci strains predominantly associated with avian chlamydiosis and human psittacosis using BALB/c mice Introduction……………………………………………………………… -
Koala Immunogenetics and Chlamydial Strain Type Are More
www.nature.com/scientificreports OPEN Koala immunogenetics and chlamydial strain type are more directly involved in chlamydial disease progression in koalas from two south east Queensland koala populations than koala retrovirus subtypes Amy Robbins1,2, Jonathan Hanger2, Martina Jelocnik1, Bonnie L. Quigley1 & Peter Timms1* Chlamydial disease control is increasingly utilised as a management tool to stabilise declining koala populations, and yet we have a limited understanding of the factors that contribute to disease progression. To examine the impact of host and pathogen genetics, we selected two geographically separated south east Queensland koala populations, diferentially afected by chlamydial disease, and analysed koala major histocompatibility complex (MHC) genes, circulating strains of Chlamydia pecorum and koala retrovirus (KoRV) subtypes in longitudinally sampled, well-defned clinical groups. We found that koala immunogenetics and chlamydial genotypes difered between the populations. Disease progression was associated with specifc MHC alleles, and we identifed two putative susceptibility (DCb 03, DBb 04) and protective (DAb 10, UC 01:01) variants. Chlamydial genotypes belonging to both Multi-Locus Sequence Typing sequence type (ST) 69 and ompA genotype F were associated with disease progression, whereas ST 281 was associated with the absence of disease. We also detected diferent ompA genotypes, but not diferent STs, when long-term infections were monitored over time. By comparison, KoRV profles were not signifcantly associated with disease progression. These fndings suggest that chlamydial genotypes vary in pathogenicity and that koala immunogenetics and chlamydial strains are more directly involved in disease progression than KoRV subtypes. Chlamydial disease is a signifcant contributing factor afecting population viability in some declining northern Australian koala populations 1. -
Expression Patterns of Five Polymorphic Membrane Proteins During the Chlamydia Abortus Developmental Cycle
Edinburgh Research Explorer Expression patterns of five polymorphic membrane proteins during the Chlamydia abortus developmental cycle Citation for published version: Wheelhouse, N, Sait, M, Wilson, K, Aitchison, K, McLean, K, Smith, DGE & Longbottom, D 2012, 'Expression patterns of five polymorphic membrane proteins during the Chlamydia abortus developmental cycle', Veterinary Microbiology, vol. 160, no. 3-4, pp. 525-9. https://doi.org/10.1016/j.vetmic.2012.06.017 Digital Object Identifier (DOI): 10.1016/j.vetmic.2012.06.017 Link: Link to publication record in Edinburgh Research Explorer Document Version: Publisher's PDF, also known as Version of record Published In: Veterinary Microbiology Publisher Rights Statement: Available under Open Access General rights Copyright for the publications made accessible via the Edinburgh Research Explorer is retained by the author(s) and / or other copyright owners and it is a condition of accessing these publications that users recognise and abide by the legal requirements associated with these rights. Take down policy The University of Edinburgh has made every reasonable effort to ensure that Edinburgh Research Explorer content complies with UK legislation. If you believe that the public display of this file breaches copyright please contact [email protected] providing details, and we will remove access to the work immediately and investigate your claim. Download date: 02. Oct. 2021 Veterinary Microbiology 160 (2012) 525–529 Contents lists available at SciVerse ScienceDirect Veterinary Microbiology jo urnal homepage: www.elsevier.com/locate/vetmic Short communication Expression patterns of five polymorphic membrane proteins during the Chlamydia abortus developmental cycle a, a a a a Nick Wheelhouse *, Michelle Sait , Kim Wilson , Kevin Aitchison , Kevin McLean , a,b a David G.E.