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15248 Federal Register / Vol. 65, No. 56 / Wednesday, March 22, 2000 / Rules and Regulations 750(4), 340±020±750(4)(b), 340±020± 300965 in the subject line on the first consists of the documents specifically 800(3)-(6), 340±020±890(5), 340±020± page of your response. referenced in this action, and other 900(6)(c), 340±020±910(1)(b), 340±020± FOR FURTHER INFORMATION CONTACT: By information related to this action, 1000(1)(a) and (2), and 340±020± mail: Vera Soltero, Registration Division including any information claimed as 1030(2). (7505C), Office of Pesticide Programs, Confidential Business Information (CBI). (C) EPA approves the changes made to Environmental Protection Agency, Ariel This official record includes the certain sections of the Oregon Rios Bldg., 1200 Pennsylvania Ave., documents that are physically located in Administrative Rules: ``Determining NW., Washington, DC 20460; telephone the docket, as well as the documents Conformity of General Federal Actions number: (703) 308±9359; and e-mail that are referenced in those documents. to State and Federal Implementation address: [email protected]. The public version of the official record Plans' found in: OAR 340±020±1510, SUPPLEMENTARY INFORMATION: does not include any information 340±020±1520, 340±020±1530, 340± claimed as CBI. The public version of 020±1570, 340±020±1580, and 340±020± I. General Information the official record, which includes 1590, effective September 23, 1998. A. Does This Action Apply to Me? printed, paper versions of any electronic comments submitted during an [FR Doc. 00±6969 Filed 3±21±00; 8:45 am] You may be affected by this action if BILLING CODE 6560±50±P applicable comment period is available you are an agricultural producer, food for inspection in the Public Information manufacturer, or pesticide and Records Integrity Branch (PIRIB), ENVIRONMENTAL PROTECTION manufacturer. Potentially affected Rm. 119, Crystal Mall #2, 1921 Jefferson AGENCY categories and entities may include, but Davis Hwy., Arlington, VA, from 8:30 are not limited to: a.m. to 4 p.m., Monday through Friday, 40 CFR Part 180 excluding legal holidays. The PIRIB telephone number is (703) 305±5805. [OPP±300965; FRL±6485±3] Cat- NAICS Examples of poten- II. Background and Statutory Findings RIN 2070±AB78 egories codes tially affected entities In the Federal Register of September Industry 111 Crop production 1, 1999 (64 FR 47788) (FRL±6098±6), Cucurbitacins; Exemption from the EPA issued a notice pursuant to section Requirement of a Tolerance 112 Animal production 311 Food manufacturing 408 of the Federal Food, Drug, and AGENCY: Environmental Protection 32532 Pesticide manufac- Cosmetic Act (FFDCA), 21 U.S.C. 346a, Agency (EPA). turing as amended by the Food Quality Protection Act (FQPA) (Public Law 104± ACTION: Final rule. This listing is not intended to be 170) announcing the filing of a pesticide SUMMARY: This regulation establishes an exhaustive, but rather provides a guide tolerance petition by, Agricultural exemption from the requirement of a for readers regarding entities likely to be Research Services, United States tolerance for residues of cucurbitacins affected by this action. Other types of Department of Agriculture, Agricultural from the powders and juices of the entities not listed in the table could also Research Center, Beltsville, MD 20705. Hawkesbury melon Citrullus lanatus on be affected. The North American This notice included a summary of the various food commodities when Industrial Classification System petition prepared by the petitioner applied/used as an inert (other) (NAICS) codes have been provided to United States Department of ingredient (gustatory stimulant) in assist you and others in determining Agriculture. There were no comments pesticides applied to growing crops whether or not this action might apply received in response to the notice of only. Agricultural Research Services, to certain entities. If you have questions filing. The petition requested that 40 CFR United States Department of Agriculture regarding the applicability of this action 180.1001(d) be amended by establishing submitted a petition to EPA under the to a particular entity, consult the person an exemption from the requirement of a Federal Food, Drug, and Cosmetic Act, listed under FOR FURTHER INFORMATION tolerance for residues of cucurbitacins as amended by the Food Quality CONTACT. derived from the Hawkesbury melon Protection Act of 1996, requesting an B. How Can I Get Additional Citrullus lanatus. The petitioner noted exemption from the requirement of a Information, Including Copies of This that the Agency had previously tolerance. This regulation eliminates the Document and Other Related established exemptions from the need to establish a maximum Documents? requirement of a tolerance for the use of permissible level for residues of 1. Electronically. You may obtain buffalo gourd and zucchini juice, as cucurbitacins from Hawkesbury melon. electronic copies of this document, and sources of the inert ingredient DATES: This regulation is effective certain other related documents that cucurbitacin (57 FR 40128, September 2, March 22, 2000. Objections and requests might be available electronically, from 1992 and 63 FR 43085, August 12, for hearings, identified by docket the EPA Internet Home Page at http:// 1998), and is seeking to add the control number OPP±300965, must be www.epa.gov/. To access this Hawkesbury melon Citrullus lanatus as received by EPA on or before May 22, document, on the Home Page select an additional source of cucurbitacins. 2000. ``Laws and Regulations'' and then look Section 408(b)(2)(A)(i) of the FFDCA ADDRESSES: Written objections and up the entry for this document under allows EPA to establish an exemption hearing requests may be submitted by the ``Federal Register-Environmental from the requirement for a tolerance (the mail, in person, or by courier. Please Documents.'' You can also go directly to legal limit for a pesticide chemical follow the detailed instructions for each the Federal Register listings at http:// residue in or on a food) only if EPA method as provided in Unit VIII. of the www.epa.gov/fedrgstr/. determines that the tolerance is ``safe.'' ``SUPPLEMENTARY INFORMATION.'' 2. In person. The Agency has Section 408(b)(2)(A)(ii) defines ``safe'' to To ensure proper receipt by EPA, your established an official record for this mean that ``there is a reasonable objections and hearing requests must action under docket control number certainty that no harm will result from identify docket control number OPP± OPP±300965. The official record aggregate exposure to the pesticide VerDate 20<MAR>2000 17:06 Mar 21, 2000 Jkt 190000 PO 00000 Frm 00046 Fmt 4700 Sfmt 4700 E:\FR\FM\22MRR1.SGM pfrm02 PsN: 22MRR1 Federal Register / Vol. 65, No. 56 / Wednesday, March 22, 2000 / Rules and Regulations 15249 chemical residue, including all effects are expected to occur. Neither contains 0.00139 grams of cucurbitacin. anticipated dietary exposures and all cucurbitacins nor their metabolites are Thus, even under these worst case other exposures for which there is known or expected to have any effect on assumptions, consumption of a pound reliable information.'' This includes the immune or the endocrine systems. of treated corn would add less exposure through drinking water and in These chemicals are not known to be cucurbitacin to the diet than a gram residential settings, but does not include carcinogenic. serving of squash. At the allowable rate occupational exposure. Section According to information supplied by of application the proposed use of these 408(b)(2)(C) requires EPA to give special USDA, the Hawkesbury watermelon compounds as inert ingredients would consideration to exposure of infants and contains cucurbitacin E-glycoside at result in a negligible increase in children to the pesticide chemical levels in the same order of magnitude exposure to cucurbitacins over those residue in establishing a tolerance and those found in buffalo gourd root levels which would occur naturally as to ``ensure that there is a reasonable powder, 0.76 milligrams (mg) the result of ingestion of various certainty that no harm will result to cucurbitacin E-glycoside/grams (gm) of cucurbit commodities. infants and children from aggregate melon compared to 0.59 mg 2. Drinking water exposure. The exposure to the pesticide chemical cucurbitacin E-glycoside/gm of root Agency review cited in the August 12, residue.* * *'' powder. The Hawkesbury melon does 1998, Federal Register notice EPA performs a number of analyses to not contain cucurbitacin I. Cucurbitacin established that most cucurbitacins are determine the risks from aggregate I is considered to be more toxic than insoluble in water and transfer of these exposure to pesticide residues. First, cucurbitacin E-glycoside (LD50 of 40 cucurbitacins to ground water is EPA determines the toxicity of milligrams/kilograms (mg/kg) to 5 mg/ unlikely. The more water soluble pesticides. Second, EPA examines kg). Thus, Hawkesbury melon is also glycosylated forms of cucurbitacins are exposure to the pesticide through food, likely to exhibit lower toxicity than less toxic to humans. No uses are drinking water, and through other buffalo gourd root powder, providing an registered for application to bodies of exposures that occur as a result of additional margin of safety. water. pesticide use in residential settings. IV. Aggregate Exposures B. Other Non-Occupational Exposure III. Toxicological Profile In examining aggregate exposure, There
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