Summer 2021 | Volume 11, No. 2 HOME << | >>

News from the Roberta and Stephen R. Weiner Department of Surgery at Beth Israel Deaconess Medical Center INSIDE SURGERY

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3  Surgery Research 14 News Briefs 6 A Point of Pride 19 Teaching Awards 7  2021 Graduates 20  Welcome New Trainees 8 Selected Publications 22 Harvard Surgery Research Day Summer 2021 10 HMS Promotions 23 In Memoriam Volume 11, No. 2 12 Alumni Spotlight: 24 Gift Supports Pancreatic Inside Surgery is published by the Prathima Nandivada, MD Cancer Research Office of the Chairman of the 13  New Faculty Roberta and Stephen R. Weiner Department of Surgery at Beth Israel Deaconess Medical Center for faculty, trainees, staff, alumni, Message from the Chair affiliates, and friends.

The mission of the s we emerge from the pandemic with hope of Department of Surgery: returning to the life we once knew, we remember A • Provide care of the very those who lost loved ones or livelihoods, or who struggle highest quality to regain a sense of balance and community. All of us • Improve health through continue to bear witness to the fragility of our global innovation and discovery community and the transience of health and well-being. • Prepare future leaders in American surgery As a society, we have long embraced the critical importance of fostering • Serve our communities with the generation of knowledge to make a difference in every facet of our lives. sensitivity and compassion One truly remarkable aspect of the past 18 months was our capacity to mobilize every available resource from the worlds of science, public policy, Surgery Chair and public health to “work the problem.” This effort catalyzed new fields of Elliot Chaikof, MD, PhD therapeutics of unprecedented efficacy and novel approaches to evaluating Editor/Writer Hilary Bennett and translating discoveries. Photography The generation of knowledge through research has been a cornerstone Danielle Duffey/BIDMC of our department since its founding. As you will read in our cover story, James Dwyer/BIDMC virtually all of our faculty and trainees conduct research that is transforming our understanding and treatment of challenging diseases, enhancing Please forward comments, news surgical training, and revealing and finding solutions to address disparities items, and requests to be added to or removed from the mailing list to: in surgical care. Editor, Inside Surgery, Beth Israel We believe that for research to thrive and bear fruit, it requires an Deaconess Medical Center, optimal milieu. We understand that innovation and discovery do not occur Department of Surgery, LMOB-9C, 110 Francis St., Boston, MA 02215. in isolation but rather at the interface of disciplines, where diverse viewpoints E-mail: surgerycommunications@ interact, problems are examined from multiple perspectives, and ideas bidmc.harvard.edu germinate into new solutions to intractable clinical problems. Thus, we Tel: 617-632-9581 continually strive to foster innovation by providing an environment that bidmc.org/surgery nurtures intellectual diversity, embraces individual freedom and flexibility, and promotes spontaneity and originality. By embracing these values, Cover photo: Susan Hagen, PhD, we are able to further our mission to develop more effective approaches Associate Vice Chair for Research to promote health and well-being, prevent illness, and treat or cure disease. in the Department of Surgery and Director of the BIDMC Microscopy The author and aviator Antoine de Saint-Exupéry wrote, “As for the future, and Histopathology Cores. Dr. Hagen’s your task is not to foresee it, but to enable it.” By questioning the status quo, research focuses on the development innovating, and collaborating, the women and men of the Department of of gastric cancer, one of the leading causes of cancer deaths worldwide. Surgery work together to enable an equitable future where each and every one of us will be graced with better, healthier lives. Follow us on Twitter @BIDMCSurgery Follow us on Instagram @BIDMCSurgery

Elliot Chaikof, MD, PhD bidmc.org/surgery Inside Surgery | Summer 2021 — Page 2 HOME << | >>

ymphedema is an incurable, painful, and Lpotentially life-threatening condition that affects 1.2 million patients in the United States, most of whom have undergone surgery for breast cancer, which often requires the removal of lymph nodes. To plastic surgeon Dhruv Singhal, MD, Director of Lymphatic Surgery at BIDMC, this state of affairs is simply unacceptable. So, when he is not providing the latest treatments for patients with or at high risk of lymphedema, he is engaged in research focused on improving their care and, ideally, preventing the condition entirely. “One of the biggest challenges we face Dhruv Singhal, MD (left), conducts NIH-funded research aimed in treating lymphedema is that the current at predicting and preventing lymphedema. understanding of the lymphatic system is limited, and we also have no way to accurately measure its an intensely painful and potentially life-threatening function,” says Dr. Singhal, who is also Co-director condition—in patients with sickle cell disease. of the Boston Lymphatic Center. It is also true for surgical oncologist A. James Thanks to Dr. Singhal’s ongoing research, that Moser, MD, who is collaborating with researchers will likely change. Earlier this year, Dr. Singhal nationwide to identify biomarkers for the diagnosis received an R01 grant from the National Institutes and targeted treatment of pancreatic cancer (see of Health (NIH) to fund his research project that page 24), and Christiane Ferran, MD, PhD, whose seeks to define the anatomy of an alternate Harvard Medical School-funded research may lead pathway involved in lymphatic drainage from the to a novel treatment for type 1 diabetes that does arm (see page 16). He and his team will map its not require insulin. variations in both healthy women and those who have undergone breast cancer treatment that puts Surgery Research Leadership them at high risk for lymphedema. With this information, surgeons could predict Richard D. Cummings, PhD which variations predispose breast cancer Vice Chair, Basic and patients to develop lymphedema. Dr. Singhal then Translational Research plans to develop a novel method of noninvasive intraoperative optical imaging to assess the function of this pathway during surgery. “This would Susan Hagen, PhD enable us to predict a patient’s risk of developing Associate Vice Chair, Research lymphedema and, if warranted, implement preventive interventions,” says Dr. Singhal.

Unsolved problems an inspiration Benjamin James, MD, MS For surgeon-scientists like Dr. Singhal, as well as Director, Resident Research non-clinical researchers in the Department of Surgery, the inspiration for their research—the question they “own”—often arises from unsolved James Rodrigue, PhD problems in the clinic, which fuels their passion Vice Chair, Clinical Research to find answers that will improve patients’ lives. That is certainly the case for Richard D. Cummings, PhD, whose laboratory research led to a new, FDA-approved treatment that significantly reduces the frequency of vaso-occlusive crises— Continued on page 4 >

bidmc.org/surgery Inside Surgery | Summer 2021 — Page 3 HOME << | >> < Continued from page 3

And it is likewise the case for the scores of other Interdisciplinary Research surgeon-scientists and laboratory investigators—as well as the trainees they mentor—in the Department Research is conducted in all of our clinical divisions of Surgery, whose research is inspired by unsolved as well as our interdisciplinary research programs, problems and the patients it may someday benefit. which foster collaborations among investigators throughout Boston, the nation, and the world, in A cornerstone of the department both academia and the life sciences and medical technology industries. Research has been a cornerstone of the Department of Surgery since its founding more • Center for Drug Discovery and Translational than 150 years ago. Today, all divisions and nearly Research; Director: Lijun Sun, PhD all faculty members participate in translational or • Center for the Study of Nutrition Medicine; clinical research programs, receiving funding from Directors: Richard D. Cummings, PhD, Jin-Rong multiple sources. Many of these programs include Zhou, PhD undergraduates, medical students, and residents • Harvard Medical School Center for Glycoscience; pursuing research electives and fellowships, as well Director: Richard D. Cummings, PhD as postdoctoral fellows. Additionally, numerous • Rongxiang Xu, MD Center for Regenerative research nurses, clinical coordinators, and Therapeutics; Director: Aristidis Veves, MD, DSc biostatisticians support these research efforts, which take place in 25,000 square feet of space across the BIDMC campus. The types of research in which the department is engaged are diverse and span the entire spectrum 580+ Scholarly Articles from bench to bedside. For example, investigators conduct laboratory-based research to define the Members of the Department of Surgery molecular basis of disease; develop novel surgical disseminate their findings internationally by publishing, on average, 580+ peer-reviewed approaches, tools, and devices; and evaluate the scholarly articles a year, as well as numerous effectiveness of competing interventions. They also chapters and textbooks in the fields of surgery carry out studies of large communities that shed and biomedical sciences. Many faculty also serve light on disparities in the delivery of surgical care as editors or reviewers for high-impact scholarly or access to treatment for society’s most vulnerable journals such as JAMA, New England Journal of citizens. In addition, investigators conduct research Medicine, Lancet, Science, and Nature. to determine the best ways to train surgeons to meet the challenges of the 21st century.

Research Grants by Division* Acute Care Surgery, Trauma, and Surgical Critical Care $4,246,546 Vascular and Endovascular Surgery $6,313,045 Cardiac Surgery $218,600 Urologic Surgery General Surgery $893,625 $992,566 Interdisciplinary Surgery Transplant Surgery $2,438,158 $2,148,440 Neurosurgery Thoracic Surgery and $302,256 Interventional Pulmonology $406,566 Plastic and Reconstructive Surgery $187,515 Surgical Oncology Podiatric Surgery $1,458,502 $1,522,767

*Fiscal year 2020 (October 1, 2019-September 30, 2020); includes research training grants bidmc.org/surgery Inside Surgery | Summer 2021 — Page 4 HOME << | >>

$21M+ in Research Funding The Department of Surgery’s total research funding from all sources, including the National Institutes of Health (NIH), exceeded $21 million in fiscal year (FY) 2020. In addition to federal grants from the NIH, the Department of Defense, the Health Resources and Service Administration, and other federal agencies, our investigators receive funding from Harvard Medical School, foundations, industry, and generous donors.

as part of their surgical training. Still, another is the FIRST (Facilitating Innovative Through the department’s Center for Drug Research and Surgical Trials) Program, which Discovery and Translational Research—one of provides faculty and trainees with comprehensive several interdisciplinary research programs— clinical research support from staff with extensive research teams are designing new molecular experience in all facets of clinical research. The and biologic agents to treat patients with cancer FIRST Program also hosts research-focused and other serious conditions. Researchers in seminars throughout the academic year. the department are also investigating novel applications of machine learning and recent Research training grants innovations in the field of data science. The department is the recipient of numerous research training grants from the NIH. These include Innovative programs support research its longstanding T32 training grant in vascular To support faculty and trainees in these and all surgery research and a T35 grant supporting research endeavors, the Department of Surgery summer research opportunities for medical has introduced a number of innovative programs students. In addition, the department was awarded over the past 10 years. two Mentored Clinical Scientist awards from the One, which was recently described in the NIH to assist clinical fellows with their transition to journal Academic Medicine, is the Surgical becoming independent research investigators. Program in Innovation (SPIN). SPIN is a six-month The department’s research has an international workshop-based curriculum to teach surgical impact, reaching and influencing investigators trainees the basics of the innovation process, worldwide through the publication each year focusing on problem identification, product design, of hundreds of scholarly papers in high-impact, prototype fabrication, and initial steps in the peer-reviewed scientific journals (see page 4) and commercialization process. Taught by medical, the faculty’s leadership in influential surgical and engineering, and medical technology industry scientific organizations. But its most significant faculty, participants collaborate in teams to develop impact—today and in the future—is in the lives a novel device, fabricate a prototype, and pitch their of patients. product to a panel of judges. Another is the Clinical Scholarship Program, which pairs all first-year categorical general ➔ For a comprehensive look at the surgery residents with a faculty research mentor, Department of Surgery’s research, who guides the residents throughout the year as please see our annual Surgery they acquire the skills to develop and implement a Research Reports via the home page of our website. To request clinical research project. In 2020, Harvard Medical a print copy of the latest (FY 2020) School recognized the Clinical Scholarship Program Surgery Research Report, with its annual Program Award for a Culture of please email us at: Excellence in Mentoring. Nearly all Surgery residents [email protected]. pursue a two- or three-year research fellowship bidmc.org/surgery Inside Surgery | Summer 2021 — Page 5 HOME << | >> A Point of Pride Department Fosters an Inclusive Culture

hen resident Daniel Cloonan, MD, was in his Wfinal year of medical school at the University of Nebraska, he had little doubt about which surgical residency program would be his top choice. Jordan Broekhuis, MD, his partner since medical school, was a first-year resident in the BIDMC General Surgery Residency Program and spoke highly not only about his training but also the inclusive culture for all residents, including LGBTQ+ individuals. “I knew from Jordan and the residents I met through him that I would also feel welcome, safe, and valued in the BIDMC program,” says Dr. Cloonan, a PGY3 who is now in the first year The new “Progress Pride” flag was hoisted at the Massachusetts of his research elective at Massachusetts State House in Boston in June 2020. The flag is explicitly inclusive General Hospital. of transgender people and people of color. The other programs Dr. Cloonan interviewed Dr. Digesu, who serves on the Surgery DEI with had no representation from the queer Committee, agrees that being open about who you community, while it was clear during his interviews are is vital to thriving during the rigors of surgical at BIDMC that being openly gay was not only training. “It is important to feel comfortable talking accepted but also celebrated. Having witnessed about your life with colleagues with whom you and experienced mistreatment and derogation spend so much time over many years, sometimes throughout his education, Dr. Cloonan finds it in stressful circumstances,” he says. a relief to work in an environment where he can All three doctors applaud the department’s be fully himself with fellow trainees and faculty multi-faceted, ongoing efforts to achieve greater members without fear of negative consequences. diversity, equity, and inclusion, and believe it is As a white man, Dr. Cloonan acknowledges that making significant progress, as evidenced by the he has it easier than others in the queer community, award it recently received from Harvard Medical including women, people of color, and transgender School (see page 14). While they acknowledge individuals. Still, he believes that the department’s there is still work to be done, they agree that the inclusive culture benefits everyone in its training department’s longtime commitment to DEI programs, likening it to “a rising tide that raises makes it easier to identify and address areas all boats.” for improvement. Dr. Broekhuis, a PGY4 who is now in the first “Our [general surgery] program director year of his research elective at BIDMC, is equally Dr. [Tara] Kent, Dr. Chaikof, and the other leaders positive about his experiences as an applicant the department have always made it clear that and resident. When he was interviewing in 2017, they value the whole person, regardless of their he attended a department-sponsored dinner gender, sexual orientation, or background,” says where Christopher Digesu, MD, a general surgery Dr. Broekhuis. “They see applicants and trainees residency alumnus who is now a cardiothoracic as individuals who have unique backgrounds and surgery fellow at BIDMC, was in attendance with strengths, and strive to help them become the best his then partner. “The clear LGBTQ+ visibility at this possible surgeons they can be.” recruitment event spoke volumes about the training program,” says Dr. Broekhuis. “I got the sense—since To learn more about the Department of Surgery fully justified—that these are my people and that ➔ Committee on Diversity, Equity, and Inclusion, they would support me.” visit our website: bidmc.org/surgery. bidmc.org/surgery Inside Surgery | Summer 2021 — Page 6 HOME << | >> Congratulations to Our 2021 Graduates

Recent graduates of the General Surgery and Integrated Vascular Surgery Residency Programs (from left): Christopher Barrett, MD, Jordan Pyda, MD, MPH, Nicholas Swerdlow, MD, Patric Liang, MD (Integrated Vascular Surgery), Asish Misra, MD, PhD, Kortney Robinson, MD, MPH, Borami Shin, MD, and Charity Glass, MD, MPP. Not pictured is Shen Li, MD.

RESIDENTS FELLOWS

General Surgery Acute Care Surgery Minimally Invasive Christopher Barrett, MD Stephanie Maroney, MD Urologic Surgery Fellowship: Surgical Critical Care, Advanced GI and Minimally Da David Jiang, MD Boston Medical Center Invasive Surgery Plastic and Charity Glass, MD, MPP* Keitaro Nakamoto, MD Fellowship: Breast Surgical Oncology Reconstructive Surgery Breast Surgical Oncology Aesthetic and Shen Li, MD* Stephanie Serres, MD, PhD Fellowship: Surgical Oncology, Reconstructive Surgery University of Chicago Cardiothoracic Surgery Ashley Nadia Boustany, MD Ammara Abbasi Watkins, Microsurgery Asish Misra, MD, PhD MD, MPH Fellowship: Transplant Surgery, Amy Maselli, MD Colon and Rectal Surgery Keck School of Medicine of USC Surgical Critical Care Jeremy Dressler, MD Jordan Pyda, MD, MPH Eran Brauner, MD Fellowship: Transplant Surgery, Endovascular and Operative Vascular Surgery The Johns Hopkins Hospital Neurovascular Surgery Melinda Schaller, MD Dominic Harris, MD Kortney Robinson, MD, MPH Fellowship: Cardiothoracic Surgery, Hand/Upper Extremity Surgery Baylor Scott & White Dallas-Fort Worth Rikesh Gandhi, MD Borami Shin, MD Swapnil Kachare, MD Fellowship: Cardiothoracic Surgery, Brian Schurko, MD Brigham and Women’s Hospital Interventional Pulmonology Nicholas Swerdlow, MD Hyun Kim, MD Fellowship: Vascular Surgery, Anastasiia Rudkovskaia, MD Beth Israel Deaconess Medical Center Faisal Shaikh, MD Sandeep Somalaraju, MD Integrated Vascular Surgery Patric Liang, MD Advanced Diagnostic Bronchoscopy Podiatric Surgery Anjan Devaraj, MD Casey Lewis, DPM Shahzad Khan, MD John Martucci, DPM Keren Mendez-Ramirez, MD * Graduating Fall 2021 Sidra Raoof, MD bidmc.org/surgery Inside Surgery | Summer 2021 — Page 7

HOME << | >> Selected Publications

Acute Care Surgery, Trauma, Neurosurgery Otolaryngology/Head and Surgical Critical Care Cavalcanti DD, Nelson PK, Raz E, Shapiro M, and Neck Surgery Ledderose C, Bromberger S, Slubowski CJ, Nossek E, Tanweer O, Riina HA; Endovascular Gomez ED, Ceremsak JJ, Leibowitz A, Jalisi S. Sueyoshi K, Junger WG. Frontline Science: Neurosurgery Research Group (ENRG) A novel cough simulation device for P2Y11 receptors support T cell activation by including Ogilvy CS and Thomas AJ. education of risk mitigation techniques directing mitochondrial trafficking to the Endovascular treatment of aneurysms using during aerosol-generating medical immune synapse. J Leukoc Biol flow-diversion embolization: 2-dimensional procedures. Otolaryngol Head Neck Surg 2021;109(3):497-508. operative video. Oper Neurosurg 2021; in press. 2021;20(4):E284-5. Narula N, Tsikis S, Jinadasa SP, Parsons CS, Naples JG, Castellanos I, Moberly AC. Cook CH, Butt B, Odom SR. The effect of Gomez-Paz S, Akamatsu Y, Salem MM, Considerations for integrating cognitive anticoagulation and antiplatelet use in Enriquez-Marulanda A, Robinson TM, Ogilvy testing into adult cochlear implant trauma patients on mortality and length CS, Thomas AJ, Moore JM. Upfront middle evaluations: Foundations for the future. JAMA of stay. Am Surg 2021; in press. meningeal artery embolization for treatment Otolaryngol Head Neck Surg 2021; in press. of chronic subdural hematomas in patients Siracusa R, Schaufler A, Calabrese V, Fuller with or without midline shift. Interv Rubin SJ, Wu KY, Kirke DN, Ezzat WH, Truong PM, Otterbein LE. Carbon monoxide: From Neuroradiol 2020;Dec 29:1591019920982816. MT, Salama AR, Jalisi S. Head and neck poison to clinical trials. Trends Pharmacol Sci cancer complications in the geriatric 2021;Mar 26:S0165-6147(21)00041-9. Mackel CE, Nelton EB, Reynolds RM, Fox WC, population based on hospital case volume. Spiotta AM, Stippler M. A scoping review of Ear Nose Throat J 2021;100(2):NP62-68. Bariatric and Minimally burnout in neurosurgery. Neurosurgery 2021:nyaa564. Invasive Surgery Plastic and Maragkos GA, Filippidis AS, Chilamkurthy S, Abdalla M, Jones DB. Weight loss following Reconstructive Surgery Salem MM, Tanamala S, Gomez-Paz S, Rao Roux-en-Y gastric bypass causally Crystal DT, Cuccolo NG, Plewinski MJ, P, Moore JM, Papavassiliou E, Hackney D, implicated with serum levels of IL-22: A Ibrahim AMS, Sinkin JC, Lin SJ, Agag RL, Thomas AJ. Automated lateral ventricular and Mendelian randomization and phenome- Lee BT. Assessment of opioid-prescribing cranial vault volume measurements in 13,851 wide association study. Obesity practices in breast augmentation: Future subjects utilizing deep learning algorithms. 2021;29(3):610-5. directions for prescribing guidelines. Ann World Neurosurg 2021;148:e363-73. Plast Surg 2021;86(1):11-8. Jones DB, Abu-Nuwar MRA, Ku CM, Berk LS, Salem MM, Maragkos GA, Gomez-Paz S, Trainor LS, Jones SB. Less pain and earlier Del Valle DD, Pardo JA, Maselli AM, Valero Ascanio LC, Ngo LH, Ogilvy CS, Thomas AJ, discharge after implementation of a MG, Fan B, Seyidova N, James TA, Lee BT. Moore JM. Trends of ruptured and multidisciplinary enhanced recovery after Evaluation of online Spanish and English unruptured aneurysms treatment in the surgery (ERAS) protocol for laparoscopic health materials for preventive mastectomy. United States in Post-ISAT era: A national sleeve gastrectomy. Surg Endosc Are we providing adequate information? inpatient sample analysis. J Am Heart Assoc 2020;34(12):5574-82. Breast Cancer Res Treat 2021; in press. 2021;10(4):e016998. Granoff MD, Pardo J, Singhal D. Power- Cardiac Surgery Stippler M, Keith S, Nelton EB, Parsons CS, assisted liposuction: An important tool in Singleton J, Bilello LA, Tibbles CD, Davis RB, Vervoort D, Premkumar A, Ghandour H, the surgical management of lymphedema Edlow JA, Rosen CL. Pathway-based Kpodonu J. Health system needs to establish patients. Lymphat Res Biol 2021;19(1):20-2. cardiac surgery centers. Thorac Cardiovasc reduction of repeat head computed Surg 2021; in press. tomography for patients with complicated Johnson AR, Fleishman A, Granoff MD, mild traumatic brain injury: Implementation Shillue K, Houlihan MJ, Sharma R, Kansal KJ, Colon and Rectal Surgery and outcomes. Neurosurgery Teller P, James TA, Lee BT, Singhal D. 2021;88(4):773-8. Evaluating the impact of immediate Kulaylat AN, Kulaylat AS, Schaefer EW, Mirkin lymphatic reconstruction for the surgical K, Tinsley A, Williams E, Koltun WA, Ophthalmology prevention of lymphedema. Plast Reconstr Hollenbeak CS, Messaris E. The impact Surg 2021;147(3):373e-81e. of preoperative anti-TNFα therapy Arroyo JG, Seto B, Yamada K, Zeng K, Minturn R, Lemire CA. Rapid reduction on postoperative outcomes following Kim G, Johnson AR, Hamaguchi R, of macular edema due to retinal vein ileocolectomy in Crohn’s disease. J Adondakis M, Tsai LL, Singhal D. Breast occlusion with low-dose normobaric Gastrointest Surg 2021;25(2):467-74. cancer-related lymphedema: Magnetic hyperoxia. Graefes Arch Clin Exp resonance imaging evidence of sparing Storino A, Wong D, Ore AS, Gaytan-Fuentes Ophthalmol 2021; in press. centered along the cephalic vein. J Reconstr IA, Fabrizio A, Cataldo T, Messaris E. Microsurg 2021; in press. Recurrence and survival of neuroendocrine North VS, Reshef ER, Lee NG, Lefebvre DR, neoplasms of the rectum: Single-center Freitag SK, Yoon MK. Lower eyelid experience. J Gastrointest Surg 2020; in press. malposition following repair of complex orbitofacial trauma. Orbit 2020;22:1-6. Faculty names are in bold within their primary division or center; trainee names are in italics. bidmc.org/surgery Inside Surgery | Summer 2021 — Page 8 HOME << | >> Marks H, Bucknow A, Roussakis E, Nowell N, Storino A, Drews RE, Tawa NE Jr. Malignant Vascular and Kamali P, Cascales JP, Kazei D, Lin SJ*, adnexal cutaneous tumors and role of Evans CL*. A paintable phosphorescent sentinel lymph node biopsy. J Am Coll Surg Endovascular Surgery bandage for postoperative tissue oxygen 2021;Mar 13:S1072-7515(21)00173-3. Dansey KD, Varkevisser RRB, Swerdlow NJ, Li assessment in DIEP flap reconstruction. C, de Guerre LEVM, Liang P, Marcaccio C, Sci Adv 2020;6:eabd1061. (*co- Thoracic Surgery and O’Donnell TF, Carroll BJ, Schermerhorn M. corresponding authors) Epidemiology of endovascular and open Interventional Pulmonology repair for abdominal aortic aneurysms Podiatric Surgery Kheir F, Thakore SR, Uribe Becerra JP, in the United States from 2004-2015 and Tahboub M, Kamat R, Abdelghani R, implications for screening. J Vasc Surg Matoori S, Veves A, Mooney DJ. Advanced Fernandez-Bussy S, Kaphle UR, Majid A. 2021;Feb 13:S0741-5214(21)00188-9. bandages for diabetic wound healing. Sci Cone-beam computed tomography-guided Transl Med 2021;13(585):eabe4839. electromagnetic navigation for peripheral Latz CA, Boitano L, Schwartz S, Swerdlow N, lung nodules. Respiration 2021;100(1):44-51. Dansey K, Varkevisser RRB, Patel V, Smith A, Watkins T, Theocharidis G, Lang I, Schermerhorn M. Contemporary mortality Leschinsky M, Maione A, Kashpur O, Marin-Corral J, Pascual-Guardia S, Amati F, after emergent open repair of complex Raimondo T, Rahmani S, Baskin J, Mooney D, Aliberti S, Masclans JR, Soni N, Rodriguez A, abdominal aortic aneurysms. J Vasc Surg Veves A, Garlick J. A novel three-dimensional Sibila O, Sanz F, Sotgiu G, Anzueto A, 2021;73(1):39-47. skin disease model to assess macrophage Dimakou K, Petrino R, van de Garde E, function in diabetes. Tissue Eng Part C Restrepo MI; GLIMP investigators including Latz CA, Boitano L, Schwartz S, Swerdlow N, Methods 2021;27(2):49-58. Kheir F. Aspiration risk factors, microbiology, Dansey K, Varkevisser RRB, Patel V, and empiric antibiotics for patients Schermerhorn ML. Mortality is high Surgical Education hospitalized with community-acquired following elective open repair of complex pneumonia. Chest 2021;159(1):58-72. abdominal aortic aneurysms. Eur J Vasc Bohnen JD, Chang DC, George BC. Endovasc Surg 2021;61(1):90-7. Operating room times for teaching and nonteaching cases are converging: Less time Transplant Surgery Liang P, Motaganahalli RL, Malas MB, Wang for learning? J Surg Educ 2021;78(1):148-59. Torres X, Menjivar A, Baillès E, Rangil T, GJ, Eldrup-Jorgensen J, Cronenwett JL, Nolan Delgado I, Musquera M, Paredes D, BW, Kashyap VS, Schermerhorn ML. Chung JJ, Qiu JM, Chaikof EL, Naples JG. Martínez M, Avinyó N, Vallés C, Cañas L, Protamine use in transcarotid artery Multidisciplinary care initiative: A paradigm Lorenzo D, Vila-Santandreu A, Ojeda R, revascularization is associated with lower shift in the pre-clinical curriculum. Med Educ Arcos E, De Sousa-Amorim E, Fernández A, risk of bleeding complications without higher 2021; in press. Rodrigue JR. The Spanish version of the fear risk of thromboembolic events. J Vasc Surg of kidney failure questionnaire: Validity, 2020;72(6):2079-87. Polanco-Santana JC, Storino A, Souza-Mota reliability, and characterization of living L, Gangadharan SP, Kent TS. Ethnic/racial donors with the highest fear of kidney Park DD, Chen J, Kudelka MR, Jia N, Haller bias in medical school performance failure. Transplant Direct 2021;7(2):e655. CA, Kosaraju R, Premji AM, Galizzi M, Nairn evaluation of general surgery residency AV, Moremen KW, Cummings RD, Chaikof EL. applicants. J Surg Educ 2021;Feb 23:S1931- Urologic Surgery Resident and elicited murine macrophages 7204(21)00048-9. differ in expression of their glycomes and Gershman B, Boorjian SA. When less is glycan-binding proteins. Cell Chem Biol Storino A, Polanco-Santana JC, Allar BG, more: The comparative effectiveness of 2020;Dec 29:S2451-9456(20)30514-6. Fakler MN, Wong D, Whyte R, Gangadharan partial versus radical nephrectomy. Eur SP, Kent TS. Paging patterns among junior Urol 2021;Mar 25:S0302-2838(21)00208-6. Rokosh RS, Mastracci TM, Chaikof EL. surgery residents in a tertiary care center. Society for Vascular Surgery implementation J Surg Educ 2021;Mar 31:S1931-7204(21) McConkey D, Best CJM, Gumminger JA, of clinical practice guidelines for patients 00052-0. Olumi AF. Advancing bladder preservation: with an abdominal aortic aneurysm: Biomarkers, decision-making, and therapy. Screening for an abdominal aortic Wong DJ, Miranda-Nieves D, Nandivada P, Urol Oncol 2021;39(4):199-200. aneurysm. J Vasc Surg 2021;73(4):1126-7. Patel MS, Hashimoto DA, Kent DO, Gómez- Márquez J, Lin SJ, Feldman HJ, Chaikof EL. Reitblat C, Bain PA, Porter ME, Bernstein DN, Rokosh RS, Starnes BW, Chaikof EL. Society The Surgical Program in Innovation (SPIN): Feeley TW, Graefen M, Iyer S, Resnick MJ, for Vascular Surgery implementation of A design and prototyping curriculum for Stimson CJ, Trinh QD, Gershman B. Value- clinical practice guidelines for patients with surgical trainees. Acad Med 2021; in press. based healthcare in urology: A collaborative an abdominal aortic aneurysm: Repair of review. Eur Urol 2021;Jan 4:S0302- an abdominal aortic aneurysm. J Vasc Surg Surgical Oncology 2838(20)30956-8. 2021;Feb 4:S0741-5214(21)00160-9.

Mele A, Fan B, Pardo J, Emhoff I, Beight L, Reitblat C, Bellmunt J, Gershman B. Solomon Y, Varkevisser RRB, Swerdlow NJ, Serres SK, Singhal D, Magrini L, James TA. Management of clinically regional node- Li C, Liang P, Siracuse JJ, de Borst GJ, Axillary lymph node dissection in the era positive urothelial carcinoma of the bladder. Schermerhorn ML. Outcomes following of immediate lymphatic reconstruction: Curr Oncol Rep 2021;23(2):24. transfemoral carotid artery stenting Considerations for the breast surgeon. stratified by pre-procedural symptom Unadkat P, Fleishman A, Olumi AF, Wagner J Surg Oncol 2021;123(4):842-5. status. J Vasc Surg 2020;Dec 2:S0741- A, Chang P, Kim SP, Korets R, Gershman B. 5214(20) 32503-9. NCD Risk Factor Collaboration (NCD-RisC) Contemporary incidence and predictors of including Duda RB. Heterogeneous occult inguinal lymph node metastases in Wu WW, Swerdlow NJ, Dansey K, Shuja F, contributions of change in population men with clinically node-negative (cN0) Wyers MC, Schermerhorn ML. Surgical distribution of body mass index to change penile cancer. Urology 2021;Feb 24:S0090- treatment patterns and clinical outcomes in obesity and underweight. Elife 4295(21)00196-5. of patients treated for expanding aneurysm 2021;10:e60060. sacs with type II endoleaks after endovascular aneurysm repair. J Vasc Surg Pardo JA, Fan B, Mele A, Serres S, Valero 2021;73(2):484-93. MG, Emhoff I, Alapati A, James TA. The role of Oncotype DX® recurrence score in predicting axillary response after neoadjuvant chemotherapy in breast cancer. Ann Surg Oncol 2021;28(3):1320-5. bidmc.org/surgery Inside Surgery | Summer 2021 — Page 9 HOME << | >>

The Department of Surgery congratulates the following faculty members on their recent Harvard Medical School promotions or appointments.

PROMOTED TO: ASSISTANT PROFESSOR OF SURGERY

Ryan P. Cauley, MD, MPH Dr. Cauley’s clinical focus is complex reconstructive Dr. Cauley, who joined the faculty in 2020, surgery of the head and neck, breast, thorax, and lower is a member of the Division of Plastic extremity; the treatment of facial trauma; wound and burn and Reconstructive Surgery. He is board management; and gender-affirmation surgery. In addition, certified in both plastic and reconstructive he is a key member of the new BIDMC Multidisciplinary surgery and surgical critical care. Wound Care Clinic. Dr. Cauley received his medical Dr. Cauley’s research interests encompass health degree from Weill Cornell Medicine, services, wound and burn surgery, microsurgical outcomes, graduating Alpha Omega Alpha, and completed his plastic and the optimization of surgical care in patients at high surgery residency in the Harvard Combined Plastic Surgery risk of wound complications. He also conducts research Residency Program. He later pursued clinical fellowships in of patient-reported outcome measures in the assessment acute burn surgery and reconstruction at Massachusetts of surgical efficacy and cost effectiveness. Dr. Cauley’s General Hospital, surgical critical care at Brigham and scholarship is reflected in 27 peer-reviewed publications, Women’s Hospital, and microsurgery at BIDMC. Dr. Cauley and he serves as a reviewer for the Journal of also earned a master of public health degree from Harvard Reconstructive Microsurgery. T. H. Chan School of Public Health.

APPOINTED AS: ASSISTANT PROFESSOR OF SURGERY

Kristen T. Crowell, MD she investigated sepsis in the murine model. In addition, Dr. Crowell joined the Division of Colon Dr. Crowell has led multiple clinical studies, including an and Rectal Surgery in 2020, following investigation of the compliance and efficacy of C. difficile the completion of a clinical fellowship infection treatment guidelines. Her findings have been in colorectal surgery at Cleveland Clinic published in peer-reviewed journals and presented at Foundation. Dr. Crowell’s clinical focus national meetings. is colorectal cancer and inflammatory Dr. Crowell’s scholarship is reflected in 23 publications, bowel disease (IBD). including 16 peer-reviewed papers, and she has co-authored Dr. Crowell earned her medical degree from the six book chapters. A committed educator, Dr. Crowell wrote University of Texas Medical Branch and completed her an educational module on colostomy and colostomy closure residency in general surgery at Penn State Milton S. for the Surgical Council on Resident Education (SCORE) Hershey Medical Center. During her residency, Dr. Crowell curriculum that is used nationally by surgery residents spent two years conducting research in the Department studying for exams. Dr. Crowell is also an active member of Cellular and Molecular Physiology at Penn State, where of several national professional societies.

PROMOTED TO: ASSISTANT PROFESSOR OF SURGERY

Arriyan Samandar (Sammy) Dr. Dowlatshahi received his medical degree from Dowlatshahi, MD Albert Ludwig University of Freiburg, Germany. He Dr. Dowlatshahi is a plastic surgeon with completed an integrated plastic surgery residency at the added qualification in hand surgery. University of Massachusetts, and a fellowship in hand and He joined BIDMC in 2017 and holds a microsurgery at BIDMC. dual appointment in the Department Dr. Dowlatshahi’s clinical expertise is in hand surgery of Surgery (Division of Plastic and and complex reconstructive surgery and microsurgery with Reconstructive Surgery) and the a focus on orthoplastic surgery, which combines principles Department of Orthopedic Surgery (Division of Hand from plastic surgery and orthopedic surgery to treat and Upper Extremity Surgery). difficult musculoskeletal conditions involving bone, nerve, bidmc.org/surgery Inside Surgery | Summer 2021 — Page 10 HOME << | >> vasculature, and soft tissue. Dr. Dowlatshahi is Dr. Dowlatshahi’s scholarship is reflected in 19 publications, Director of the BIDMC Orthoplastic and Reconstructive and he has authored or co-authored five book chapters. He is Microsurgery Program. a core faculty member of the Harvard Combined Orthopaedic Among other accomplishments, Dr. Dowlatshahi has Residency Program, the BIDMC Plastic and Reconstructive increased the volume and sophistication of microsurgical Surgery Residency Program, the BIDMC Hand Surgery reconstructions at BIDMC, including using a technique known Fellowship, and the BIDMC Microsurgery Fellowship. He also as super-microsurgery, which involves operating on vessels serves as BID-Milton Site Director for BIDMC’s Plastic and and nerves with a diameter of 0.7 mm or smaller. Reconstructive Surgery Residency Program.

APPOINTED AS: PROFESSOR OF SURGERY

Devin Eckhoff, MD clinical/research fellowship in transplant surgery, also at the Dr. Eckhoff is Chief of Transplant Surgery University of Wisconsin-Madison. and Director of the Transplant Institute at Dr. Eckhoff’s major research interests have been focused BIDMC. Dr. Eckhoff was recruited to BIDMC on xenotransplantation and expanding the supply of organs in 2020 from the University of Alabama for transplantation. His work has investigated transplanting (UAB) at Birmingham, where he was genetically modified kidneys from pigs to humans, thereby Professor of Surgery and held the Arnold expanding the supply of organs for transplantation. Dr. Eckhoff’s G. Diethelm Endowed Chair in research has been supported by the National Institutes of Transplantation Surgery. Among many other leadership Health and industry, and is reflected in more than 150 published roles at UAB, Dr. Eckhoff was Director of the Division of peer-reviewed manuscripts and book chapters. Transplantation for 17 years. A Fellow of the American College of Surgeons, the Dr. Eckhoff received his medical degree from the American Surgical Association, and the American Society University of Minnesota, graduating Alpha Omega Alpha. of Transplantation, Dr. Eckhoff is frequently invited to speak Following the completion of his residency in general surgery nationally and internationally, and serves on the Council of the at the University of Wisconsin-Madison, Dr. Eckhoff pursued American Society of Transplant Surgeons. a research fellowship in transplantation and subsequently a

PROMOTED TO: ASSISTANT PROFESSOR OF OTOLARYNGOLOGY

James Naples, MD at BIDMC that integrates many of the services needed to Dr. Naples, a neurotologist who specializes manage patients with complex dizziness/vertigo. in disorders of the ear and skull base, joined Dr. Naples has diverse research interests that include the Division of Otolaryngology/Head and hearing loss due to cisplatin-induced ototoxicity and the Neck Surgery in 2019. history of medicine. He currently serves on the History Dr. Naples earned his medical degree and Archives Committee of the American Academy of from the University of Connecticut School Otolaryngology, and his research efforts are reflected in 43 of Medicine, completed his residency in peer-reviewed publications. otolaryngology at the University of Connecticut, and pursued With a longstanding interest in education, Dr. Naples a fellowship in otology/neurotology (ear diseases) at the serves as an Associate Program Director of the Otolaryngology/ University of Pennsylvania. Head and Neck Surgery Residency at BIDMC/Harvard Dr. Naples’s clinical interests include hearing loss and Medical School, and also serves on the Otology and cochlear implants, skull base surgery, acoustic neuroma, Neurotology Education Committee of the American Academy and Meniere’s disease. He established a novel “Dizzy Clinic” of Otolaryngology.

PROMOTED TO: ASSISTANT PROFESSOR OF SURGERY

Heidi Rayala, MD, PhD from Washington University School of Medicine in St. Louis. Dr. Rayala is a member of the Division of She completed an internship in surgery at Brigham and Urologic Surgery who was recruited to the Women’s Hospital, a residency in urologic surgery at the Department of Surgery in 2020 following Harvard Program in Urology (Longwood Area), and a ten years at Cambridge Health Alliance fellowship in urologic oncology at Memorial Sloan Kettering (CHA). At CHA, Dr. Rayala held numerous Cancer Center. leadership positions, including Chair of the Dr. Rayala is dedicated to teaching and serves as the Cancer Committee, where she led many supervising attending for the resident-run Genitourinary Clinic, quality-improvement projects focused on improving cancer which provides care to underserved patients. She is also course care for the underserved. instructor for the Harvard Medical School Practice of Medicine Dr. Rayala’s clinical interests include prostate cancer, Introduction to the GU exam, and co-directs the Harvard bladder cancer, kidney stone disease, erectile dysfunction, Medical School Introduction to Suturing workshop. In addition, recurrent urinary tract infections, benign prostatic hypertrophy, Dr. Rayala serves as a member of the Harvard Medical School and male and female urinary incontinence. Admissions Committee. Dr. Rayala received her medical and doctoral degrees

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Prathima Nandivada, MD, 2018 Department of Surgery, Boston Children’s Hospital Assistant Professor of Surgery, Harvard Medical School

lthough she trained and performed for Amany years as a classical vocalist, Prathima Nandivada, MD, never seriously considered a professional singing career. Instead, from a very young age her sights were always set on becoming a doctor. After graduating from Massachusetts Institute of Technology, Dr. Nandivada attended Renaissance can often reconstruct the anatomy to give these School of Medicine at Stony Brook University, fully children a normal life,” she says, noting that she intending to become an academic pediatrician. will find great satisfaction following these patients But she changed course following a sub-internship throughout their childhood. in vascular surgery at BIDMC, deciding to pursue Dr. Nandivada continues to conduct research, a career as a surgeon-scientist in vascular surgery. aiming to divide her time equally between patient “My top residency choice was BIDMC, largely care and basic and clinical research. Her basic because of its clinical and research strengths research, under the mentorship of Jerrold Turner, in vascular surgery,” says Dr. Nandivada, who MD, PhD, of Brigham and Women’s Hospital, is graduated from medical school Alpha Omega Alpha. focusing on the biology of tight junctions in the It was during her clinical rotation at Boston developing gastrointestinal tract and their role in Children’s Hospital (BCH), however, that pediatric diseases such as necrotizing enterocolitis Dr. Nandivada’s previous dream of working with and Hirschsprung disease. She will also participate children was rekindled. It was further fueled by in clinical research projects through the Colorectal her three-year research elective at BCH with and Pelvic Malformation Center under the BIDMC alumnus Mark Puder, MD, PhD, a pediatric mentorship of its director, Belinda Dickie, MD, PhD. surgeon-scientist whose translational research As much as she loves patient care and research, led to a lifesaving treatment for children with liver Dr. Nandivada’s favorite roles are teacher and disease resulting from long-term intravenous mentor, for which she has received numerous (parenteral) nutrition. “Dr. Puder has been an teaching awards. She finds it rewarding to educate influential role model who prepared me for a career parents about their child’s condition and to teach as a surgeon-scientist,” says Dr. Nandivada. residents, including those from BIDMC, in the OR, After graduating from residency in 2018, clinic, or research setting. Dr. Nandivada—now confident she had found the Dr. Nandivada also enjoys being a mentor and right career path—completed a two-year fellowship role model to trainees who seek her advice about in pediatric surgery at BCH, where she is now an how to balance a career as a surgeon-scientist with attending surgeon. “I came full circle and am now parenthood. “I tell them that in addition to having a doing what I dreamed about as a child—caring for supportive partner, a supportive residency program children and their families,” says Dr. Nandivada. is critically important,” says Dr. Nandivada, who has While she provides the full range of pediatric a five-year-old son. “I am grateful to the BIDMC general surgery, as a member of the Colorectal residency program not only for the excellent training and Pelvic Malformation Center Dr. Nandivada I received, but also for the support of so many has a particular clinical focus on the treatment outstanding faculty throughout my residency of anorectal malformations. “Over the course of and beyond.” several operations performed during infancy, we bidmc.org/surgery Inside Surgery | Summer 2021 — Page 12 HOME << | >> New Faculty For more information about our new faculty, including their clinical and research interests, practice sites, and contact information, please visit the “Find-A-Doctor” section on the BIDMC website.

ACUTE CARE SURGERY, TRAUMA, PODIATRIC SURGERY AND SURGICAL CRITICAL CARE John “JT” Marcoux, DPM Anupamaa (Anu) Seshadri, MD Medical School: Temple University Medical School: University of School of Podiatric Medicine Maryland School of Medicine Residency: Podiatric Medicine and Residency: General Surgery, Surgery, Presbyterian Medical Center, Brigham and Women’s Hospital UPenn Health System Fellowship: Surgical Critical Care, Trauma, and Acute Care Surgery, University of Pittsburgh SURGICAL ONCOLOGY Medical Center Stephanie Serres, MD, PhD Medical School: University of Texas OPHTHALMOLOGY Southwestern Medical School Alisa Prager, MD, MPH Residency: General Surgery, Beth Israel Deaconess Medical Center Medical School: Columbia University Fellowship: Breast Surgical Oncology, College of Physicians and Surgeons Beth Israel Deaconess Medical Center Residency: Ophthalmology, Northwestern University Fellowship: Glaucoma, THORACIC SURGERY AND INTERVENTIONAL Northwestern University PULMONOLOGY Chenchen Zhang, MD, PhD Joseph (Jamie) Raevis, MD Medical School: Xiangya School Medical School: Georgetown of Medicine, Central South University School of Medicine University (China) Residency: Ophthalmology, State Residency: Internal Medicine, University of New York Downstate Norwalk Hospital/Yale School Fellowship: Vitreoretinal, University of Medicine of Wisconsin-Madison Fellowships: Interventional Pulmonology, University of Pennsylvania; Pulmonary OTOLARYNGOLOGY/ Medicine and Critical Care, Saint Louis University Hospital HEAD AND NECK SURGERY Christopher Brook, MD UROLOGIC SURGERY Medical School: Albany Marissa Kent, MD Medical College Medical School: Tufts University Residency: Otolaryngology, Boston School of Medicine Medical Center Residency: Urology, Mount Fellowship: Rhinology and Anterior Sinai Hospital Skull Base Surgery, Massachusetts Fellowship: Prosthetic Surgery, Eye and Ear Infirmary Reconstructive and Transgender Urology, Mount Sinai Hospital PLASTIC AND RECONSTRUCTIVE SURGERY Ashley Nadia Boustany, MD VASCULAR AND ENDOVASCULAR SURGERY Medical School: West Virginia Patric Liang, MD University School of Medicine Medical School: Albert Einstein Residency: Plastic and Reconstructive College of Medicine Surgery, University of Kentucky School Residency: Vascular Surgery, Beth of Medicine Israel Deaconess Medical Center Fellowship: Aesthetic and Fellowship: Harvard-Longwood Reconstructive Plastic Surgery, Beth Research Fellowship Israel Deaconess Medical Center bidmc.org/surgery Inside Surgery | Summer 2021 — Page 13 HOME << | >> NEWSBRIEFS

Asish Misra, MD, PhD, a 2021 General Surgery Residency Program graduate who will be pursuing his fellowship in transplant surgery at Keck School of Medicine of USC, was awarded a $100,000 fellowship training grant from the OneLegacy Foundation in April. Dr. Misra’s project, “Nanostructured Mass Exchanger for Hepatic Replacement Therapy,” will apply his microfluidics/nanoparticle expertise toward the goal of developing a bioartificial liver. Dr. Misra will be Harvard Medical School selected the collaborating on this project with Juliet Emamaullee, Department of Surgery for the 2021 Harold MD, PhD, an abdominal organ transplant surgeon in Amos Faculty Diversity Group Award, which was the Department of Surgery at Keck School of Medicine established to recognize and celebrate those who of USC. The OneLegacy Foundation supports the have made significant achievements in moving mission of OneLegacy, the nation’s largest organ, the medical school toward being a diverse and eye, and tissue recovery organization. inclusive community. The department’s Diversity, Equity, and Michael Yaffe, MD, PhD, Acute Inclusion (DEI) Committee, formerly chaired Care Surgery, Trauma, and by Sidhu Gangadharan, MD, MHCM, Chief of Surgical Critical Care, was named Thoracic Surgery and Interventional Pulmonology, a Margaret MacVicar Faculty and now chaired by Anne Fabrizio, MD, Colon Fellow by Massachusetts Institute and Rectal Surgery, continues the longtime work of of Technology (MIT), where he Department of Surgery faculty, staff, trainees, and is the David H. Koch Professor of researchers to create a diverse community that is Biology and Biological Engineering equitable and welcoming to all. “This has always and Director of the MIT Center for Precision Cancer been a critically important area of focus for our Medicine. Dr. Yaffe also holds an appointment community, and we are truly honored to have our in the Division of Surgical Oncology in the BIDMC achievements recognized with this award,” said Department of Surgery. Surgery Chair Elliot Chaikof, MD, PhD. The MacVicar Faculty Fellows Program A virtual ceremony hosted by Harvard recognizes exemplary and sustained contributions Medical School to acknowledge and celebrate to undergraduate education at MIT. The 2021 fellows the recipients of the 2021 Harold Amos join an elite group of scholars from across MIT who Faculty Diversity Group Award was held in April. are committed to curricular innovation, scientific research, and improving the student experience through teaching, mentoring, and advising. In addition, Dr. Yaffe was elected to the Association Jacques Kpodonu, MD, Cardiac of American Physicians (AAP), an honorary medical Surgery, was a moderator society founded in 1885 for “the advancement of of an inaugural webinar on scientific and practical medicine.” Election to the AAP, congenital and pediatric heart which is limited to 70 per year, is an honor extended surgery in Africa. The program to physicians with outstanding credentials in basic was sponsored by the African or translational biomedical research. University for Thoracic and Cardiovascular Surgery, which promotes the development of cardiothoracic and vascular surgery in Africa via virtual lectures and educational webinars. Dr. Kpodonu presents and publishes frequently about global health disparities in cardiothoracic surgery. bidmc.org/surgery Inside Surgery | Summer 2021 — Page 14 HOME << | >>

Three dozen members of the Department of Surgery were named “Top Doctors” in the January 2021 issue of Boston Magazine: Drs. Jeffrey Arle, Mark Callery, David Caradonna, Thomas Cataldo, Elliot Chaikof, Peter Chang, Joseph Ciccone, Anurag Das, Lisa Ferzoco, Sidhu Gangadharan, Allen Hamdan, William Innis, Scharukh Jalisi, Ted James, Daniel Jones, Kamal Khabbaz, Ernest Kornmehl, Mark Kuperwaser, Stephen Lazarou, Bernard Lee, Samuel Lin, David Liu, Adnan Majid, Leonard Miller, Abraham Morgentaler, Donald Morris, A. James Moser, Christopher Ogilvy, Aria Olumi, Heidi Rayala, Marc Schermerhorn, Terri Silver, Sumner Slavin, Ajith Thomas, Andrew Wagner, Mark Wyers, and Richard Whyte.

Seema Anandalwar, MD (top), and Residents Sharif Sabe, MD, and Chun Li, MD, MPH, were selected as Betty Liu, MD, each received a 2021 Administrative Chief Residents of the Resident Research Award from the General Surgery Residency Thoracic Surgery Foundation, the Program for the 2021-2022 charitable arm of the Society of academic year. They were selected Thoracic Surgeons. The highly for this honor by their peers and competitive awards provide two approved by faculty because of years of financial support for their dedication to the residency, surgical trainees seeking to acquire leadership, and commitment investigational skills. Dr. Sabe’s to the education and well-being project is “The Impact of Glycemic of all residents. Control on Extracellular Vesicle- Mediated Angiogenesis in a Porcine Model of Chronic Myocardial Ischemia and Metabolic Syndrome.” Dr. Liu’s project is “Accelerating Wound Healing of Mesothelial Injuries Using a Bio- The journal Plastic and Derived Interface with the Heart and Lungs.” Reconstructive Surgery named Samuel Lin, MD, MBA, Plastic and Reconstructive Surgery, to its Joseph Ogbonna, MPH, was “Reviewer Hall of Fame” for having promoted to Director of Quality reviewed between 700-799 articles Programs in the Department of for the journal since 2004. Dr. Lin Surgery. In this role, Mr. Ogbonna serves on the journal’s editorial leads the planning, facilitation, board and is the outcomes section editor. and implementation of quality- improvement, patient-safety, and clinical-effectiveness projects Each year, the Department of Surgery and the Clinton throughout the department and its specialty divisions. and Joseph Koufman Foundation award educational After working in quality and safety management grants to four surgical nursing professionals with at Tufts Medical Center, Mr. Ogbonna joined the prominent leadership potential who also demonstrate department as Senior Quality Improvement Project humanism and excellence in patient care. The Manager in 2015. Mr. Ogbonna graduated cum laude recipients of this year’s Clinton and Joseph Koufman from American University of Nigeria with a full-tuition, Foundation Awards for Excellence are: Brianna merit-based scholarship, and later earned a Master Nadeau, BSN, RN, perioperative services; William of Public Health degree from Tufts University. Entwistle, BSN, RN, inpatient services; Sharon Kaden, PA-C, Cardiac Surgery; and Elizabeth Tillotson, RN, MSN, NP-C, ambulatory surgical care. Runners-up are: Alyssa Kuba, MSN, NP-BC, and Alec Spooner, BSN, RN, both of inpatient services.

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Cardiothoracic Surgery fellow Resident Jordan Broekhuis, MD, (thoracic track) and General who is completing his research Surgery Residency Program elective under the mentorship of alumnus Christopher Digesu, MD, Benjamin James, MD, MS, was was selected for the American selected to serve on the Association Association for Thoracic Surgery for Academic Surgery’s (AAS) (AATS) Leadership Academy, Membership Committee. The which this year focuses on a mission of the AAS, which has more diversity perspective. Through an intensive, didactic, than 4,000 members, is to inspire and develop young and interactive program, the AATS Leadership academic surgeons. Academy provides participants with administrative, interpersonal, and mentoring skills needed to succeed as academic cardiothoracic surgeons.

Resident Daniel Cloonan, MD, was selected to serve on the American Society of Transplant Surgeons (ASTS) Pipeline Taskforce. The taskforce focuses on recruiting trainees to the field of transplant surgery by establishing programming in career development, mentorship, and diversity. Ruslan Korets, MD (right), Urologic Surgery, was Dr. Cloonan also serves on the Trainee Advisory nominated for the 2021 American Urological Association Board, which is the first and only exclusively trainee (AUA) Residents and Fellows Committee Teaching group within the ASTS. This group works to guide Award for his dedication to teaching and outstanding ASTS programming from the medical student, resident, professional accomplishments. “We are grateful for and fellow perspective. Dr. Cloonan is completing Dr. Korets’s commitment to education and for providing his research elective in the Center for Transplantation an innovative learning environment for our trainees,” Sciences at Massachusetts General Hospital. says Urologic Surgery Chief Aria Olumi, MD.

Dhruv Singhal, MD, Plastic and With this information, surgeons Reconstructive Surgery, received could predict which variations an R01 grant from the National predispose breast cancer patients Heart, Lung, and Blood Institute to develop lymphedema, an of the National Institutes of Health. incurable, painful, and potentially Dr. Singhal is Co-director of life-threatening condition that the Boston Lymphatic Center, a affects 1.2 million patients in the joint program between BIDMC United States. Later, Dr. Singhal and Boston Children’s Hospital. plans to develop a novel method The grant will fund Dr. Singhal’s of noninvasive intraoperative research project entitled optical imaging to assess “Mapping and Quantifying involved in lymphatic drainage the function of this pathway Lymphatic Drainage of the from the arm. They will map its during breast cancer surgery Arm’s Alternate Pathway.” variations in both healthy women to predict a patient’s risk of Employing imaging and those who have undergone developing lymphedema and, if techniques, Dr. Singhal and breast cancer treatment that puts warranted, implement preventive his team will aim to define the them at high risk for lymphedema interventions. anatomy of an alternate pathway but did not develop the condition. bidmc.org/surgery Inside Surgery | Summer 2021 — Page 16 HOME << | >> A book authored by Per-Olof 2020 fiscal year, and reports from faculty Hasselgren, MD, PhD, “Thyroid across all divisions and interdisciplinary research Cancer & Thyroid Nodules in 30 centers. To request a print copy, contact: Minutes: A Guide to Symptoms, [email protected]. Diagnosis, Surgery, and Disease Management,” was selected as a Silver Winner in the 33rd annual Benjamin Franklin Award program (health and fitness category). Published in mid-2020, Dr. Hasselgren’s book is one of a series of “in 30 Andrew Chang, an undergraduate biology student Minutes” guides published by i30 Media. Regarded at Northeastern University, won a RISE award for his as one of the highest national honors for independent research on aromatase inhibitors and mechanisms of publishers, the Benjamin Franklin Award program resistance to benign prostatic hyperplasia, which was recognizes excellence in book editorial and design. conducted under the mentorship of Aria Olumi, MD, Chief of Urologic Surgery. RISE is an annual showcase for research and creative projects undertaken by Resident Carolina Torres Perez- Northeastern undergraduate and graduate students. Iglesias, MD, was awarded the prestigious Paul Farmer Global Surgery Research Fellowship for Daniel Jones, MD, Chief of Bariatric 2021-2023 by the Harvard Program and Minimally Invasive Surgery, in Global Surgery and Social was selected by the Society for Change. The purpose of the Surgery of the Alimentary Tract fellowship is to train leaders who will (SSAT) Foundation to receive the further promote surgical, anesthesia, and obstetrics 2021 Andrew L. Warshaw Master and gynecology care; education; research; and policy Educator Award. In 2010, the SSAT development in global surgery in resource-poor Foundation established the award settings throughout the world. Past Paul Farmer Global to recognize an outstanding surgical educator and Surgery Research fellows from the Department of mentor. Dr. Jones was presented with the award Surgery are Nakul Raykar, MD, MPH, a graduate of the at the virtual SSAT and SSAT Foundation awards General Surgery Residency Program, and Jordan ceremony in May. Pyda, MD, MPH, who graduated from the General Surgery Residency Program in June. The National Institutes of Health awarded an R01 grant to a team of investigators from BIDMC (Andrew Wagner, MD, Peter Chang, MD, MPH, Urologic Surgery, and Seymour Rosen, MD, Pathology) Thanh Dinh, DPM, Podiatric Surgery, along with a team from was installed as President of the Massachusetts Institute of American College of Foot & Ankle Technology (James Fujimoto, PhD, study principal Surgeons, the specialty’s leading investigator) to explore a new non-linear microscope organization. Dr. Dinh is Program Director of BIDMC’s (NLM) technology to assess radical prostatectomy Podiatric Medicine and Surgery Residency Program. specimen margins in real time during robotic prostatectomy. Their multidisciplinary study will first evaluate the feasibility of the NLM microscope. The annual Department of The team will subsequently conduct a randomized Surgery Research Report is controlled trial to evaluate outcomes using the NLM now available in print and technology. The study goals are to evaluate whether on the department’s website. the use of NLM can improve nerve-sparing rates and The 144-page publication cancer control during robotic prostatectomy. includes an overview of research underway within the department, a bibliography of published and in-press publications during the

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In April, resident Benjamin Allar, Teviah Sachs, MD, MPH, MD, and Gezzer Ortega, MD, MPH, a 2012 graduate of the Brigham and Women’s Hospital, BIDMC General Surgery had an opinion piece published Residency Program, was in Scientific American entitled “Our named Chief of Surgical Health System is Failing Patients Oncology at Boston with Limited English.” The authors Medical Center. Dr. Sachs highlight disparities in care due to also serves as Associate patient-provider language discordance and highlight Program Director for the surgery residency avenues to improve access to medical interpretation at Boston Medical Center. at state and local levels.

Kristina Giles, MD, a 2012 Kathryn Kowalsky, graduate of the BIDMC LICSW, Division of General Surgery Residency Acute Care Surgery, Program, was named Trauma, and Surgical Director of the Division Critical Care, received of Vascular Surgery at a certificate of Maine Medical Center. appreciation from Prior to joining Maine Blue Ledge Co-op, Medical Center in 2020, Dr. Giles practiced an affordable senior housing facility in Roslindale, Mass., for her commitment to supporting members for several years at the University of Florida. of the Blue Ledge community during the past year via a weekly virtual trauma session. Among Ms. Kowalsky’s achievements were helping build the culturally diverse residents’ trust in the COVID-19 vaccine, leading to a very high rate of vaccination, Alumni, do you have news you would and reducing their fears about going to the hospital like to share with our readers? for important medical appointments. We would love to hear from you! Please send your news to: [email protected]

< Continued from page 11 APPOINTED AS: ASSISTANT PROFESSOR OF SURGERY

Lars Stangenberg, MD, PhD hospital in Liestal, Switzerland, and subsequently an Dr. Stangenberg is a member of the attending at Rhode Island Hospital for nearly four years, Division of Vascular and Endovascular where he was an Assistant Professor of Surgery at Alpert Surgery who was recruited to the Medical School of Brown University. Department of Surgery in early 2020. Dr. Stangenberg’s clinical interests include Dr. Stangenberg received his MD endovascular and open repair of abdominal and thoracic and PhD (magna cum laude) from aortic aneurysms, carotid artery surgery and stenting, Albert Ludwig University of Freiburg, stenting and bypass surgery for peripheral vascular Germany. After a research fellowship in oncology at disease, and thoracic outlet syndrome. Massachusetts General Hospital (MGH), he completed Dr. Stangenberg’s primary research interest is aortic his general surgery residency at MGH, followed by a pathologies, and his scholarship is reflected in 19 peer- clinical fellowship in vascular and endovascular surgery reviewed publications. He is a member of the Society for at BIDMC. Clinical Vascular Surgery, the Society for Vascular Surgery, Prior to joining BIDMC, Dr. Stangenberg was an and the New England Society for Vascular Surgery, and attending surgeon at a University of Basel-affiliated is engaged in teaching trainees at all levels.

bidmc.org/surgery Inside Surgery | Summer 2021 — Page 18 HOME << | >> Teaching Awards Each June, departmental teaching awards are announced at the White Coat Ceremony, where awardees are acknowledged and rising chief residents receive their white coats from graduating chief residents. We are proud to announce this year’s award recipients and acknowledge our 2021-2022 chief residents.

HAROLD BENGLOFF, MD AWARD Stephen Odom, MD Voted by residents as the faculty member who best exemplifies humanism in teaching.

Rising chief residents wearing their new white coats (from left): Michael Dombek, MD, GEORGE W.B. Alexander Chalphin, MD, Michelle Fakler, MD, MPA, Seema Anandalwar, MD, MPH, STARKEY, MD AWARD Quynh Chu, MD, Kirsten Dansey, MD, MPH (integrated vascular surgery), Chun Li, MD, Stephen Odom, MD MPH, Daniel Wong, MD, MHS, Sarah Tracy, MD, and Lorenzo Anez-Bustillos, MD, MPH. To the faculty member with the highest-rated teaching evaluations from second-year Harvard Medical School students in the Core Surgery Clerkship.

RESIDENT TEACHER AWARD KHALID KHWAJA, MD Kortney Robinson, MD, MPH FACULTY AWARD Voted by residents as the senior David Liu, MD resident who best exemplifies To a junior clinical faculty member teaching to other residents. who best fosters a culture of PRIMARY CLINICAL EXPERIENCE collaboration, respectfulness, RESIDENT TEACHING AWARD RUSSELL J. NAUTA, MD AWARD compassion, and shared sense of Jordan Pyda, MD, MPH Kortney Robinson, MD, MPH purpose in their interactions with Selected for dedication to teaching by To the resident who best exemplifies trainees, employees, and patients. all Harvard Medical School students the compassion and commitment who rotated at BIDMC Surgery. that Dr. Nauta shared with each of his patients.

ISAAC O. MEHREZ, MD AWARD James Wallace, MD THORACIC SURGERY To the third-year resident selected SERVICE AWARDS JOHN L. ROWBOTHAM, MD AWARD by Mount Auburn Hospital surgeons To the intern and PGY4 with Amy Wyrzykowski, MD for “Dedication to the highest quality the best performance on the To the faculty member who, as care, honesty, willingness to learn, Thoracic Surgery Service. chosen by residents, best exemplifies and a sense of humor.” Jennifer Pan, MD (PGY1) excellence in clinical surgical teaching. Chun Li, MD, MPH (PGY4)

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RESIDENTS

GENERAL SURGERY: Categorical Interns GENERAL SURGERY: Preliminary Interns Huma Baig, MD Fatemeh Adiliaghdam, MD Harvard Medical School Tehran University of Medical Sciences School of Medicine Jaime Pardo Palau, MD Universidad de Los Andes Facultad de Medicina Ritah Chumdermpadetsuk, MD John Polanco Santana, MD, MSc, MPH Columbia University Vagelos College Pontificia Universidad Católica Madre y Maestra of Physicians and Surgeons Facultad de Ciencias de la Salud Mariana Juanita Rodriguez, MD Universidad de Los Andes Facultad de Medicina Nicholas DeStefino, MD Christian Schaufler, MD Harvard Medical School University of Connecticut School of Medicine

INTEGRATED VASCULAR SURGERY Jeremy Darling, MD Tufts University School of Medicine Camila Guetter, MD Universidade Federal do Paraná (UFPR) NEUROSURGERY Faculdade de Medicina Michael Avery, MD, PhD Case Western Reserve University School of Medicine

Josephine Nwokedi, MD, MBA OTOLARYNGOLOGY/HEAD AND NECK SURGERY Keck School of Medicine of the Brett Campbell, MD University of Southern California Tulane University School of Medicine Kevin Tie, MD University of North Carolina at Chapel Hill School of Medicine Jemin Park, MD University of Michigan Medical School PLASTIC AND RECONSTRUCTIVE SURGERY Helen Xun, MD Johns Hopkins University School of Medicine

Aminah Sallam, MD PODIATRIC SURGERY Yale School of Medicine Usman Aleem, DPM Barry University School of Podiatric Medicine Thao Nguyen, DPM New York College of Podiatric Medicine

Emily Scire, MD UROLOGIC SURGERY Perelman School of Medicine Sina Monfared, MD at the University of Pennsylvania Boston University School of Medicine Michelle Shabo, MD University of Massachusetts Medical School Thomas Xu, MD University of Virginia School of Medicine

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FELLOWS

ADVANCED GI AND MINIMALLY INVASIVE SURGERY MINIMALLY INVASIVE UROLOGIC SURGERY Danbee Kim, MD May Jean (“MJ”) Counsilman, MD MedStar Georgetown/Washington Hospital Center Thomas Jefferson Medical Center

CARDIOTHORACIC SURGERY PLASTIC AND RECONSTRUCTIVE SURGERY Jamal Anyalebechi, MD (Cardiac) Rachel Akintayo, MD University of Washington MedStar Georgetown/Washington University Hospital Independent Plastic Surgery Fellow Patrick Seastedt, MD (Thoracic) Weill Cornell Medicine​ Trina Ghosh, MD Washington University in St. Louis School of Medicine COLON AND RECTAL SURGERY Aesthetic and Reconstructive Surgery Eric Rosenfeld, MD, MPH Anthony Haddad, MD Baylor College of Medicine Brigham and Women’s Hospital Independent Plastic Surgery Fellow ENDOVASCULAR AND OPERATIVE Jacob Rinkinen, MD NEUROVASCULAR SURGERY Brigham and Women’s Hospital Max Shutran, MD Microsurgery Tufts Medical Center SURGICAL CRITICAL CARE HAND/UPPER EXTREMITY SURGERY Joanna Etra, MD Jimmy Chan, MD Johns Hopkins University School of Medicine Icahn School of Medicine Acute Care Surgery/Surgical Critical Care Brent Pickrell, MD Benjamin Hall, MD Brigham and Women’s Hospital Warren Alpert Medical School, Brown University Brian Schmitberg, MD Surgical Critical Care UCONN School of Medicine VASCULAR SURGERY INTERVENTIONAL PULMONOLOGY Nicholas Swerdlow, MD David Abia-Trujillo, MD Beth Israel Deaconess Medical Center Mayo Clinic Emily Schuiteman Ducomb, DO University of Vermont Medical Center Anil Magge, MD University of Connecticut Health Abhinav Mittal, MD West Virginia University Medicine

ADVANCED DIAGNOSTIC BRONCHOSCOPY Jan Fouad, MD Yale-New Haven Hospital Christian Castillo Latorre, MD VA Caribbean Healthcare System Chetana Pendkar, MD SUNY-Downstate Medical Center Aritra Sen, MD Tufts University Medical Center

Urologic Surgery interns Sina Monfared, MD, and Michelle Shabo, MD bidmc.org/surgery Inside Surgery | Summer 2021 — Page 21 HOME << | >> Harvard Surgery Research Day A Decade of Highlighting Trainees’ Research

en years ago, Surgery TChair Elliot Chaikof, MD, PhD, proposed an idea to his counterparts at Boston Children’s Hospital, Brigham and Women’s Hospital, and Massachusetts General Hospital—to engage all four of the Harvard-affiliated surgery departments in an event that would foster and highlight their trainees’ research while also creating a sense of community Marc Schermerhorn, MD (left), was the mentor for Patric Liang, MD’s research project, and collaboration among trainees which tied for second prize in the clinical/health services research category. and faculty alike. The response was enthusiastic. Each year, a committee To acknowledge all those who In May 2012, the inaugural Harvard comprising several faculty submitted posters, a booklet was Surgery Research Day was held at members from each hospital produced that listed the titles, the Joseph B. Martin Conference collaborates for months to plan the authors, mentors, and institutions Center at Harvard Medical School, event and score the submissions, of all 190 abstracts. where it has been held every rotating the responsibility for Another highlight of the day is spring except during the pandemic. event planning annually among a lecture by a nationally prominent “This event gives participants an the hospitals. surgical leader. This year’s visiting opportunity to share their research In 2021, following the usual professor was E. Shelley Hwang, with peers and faculty, learn about rigorous review process, 18 MD, MPH, Vice Chair of Research the research of others within the abstracts were chosen for virtual in the Department of Surgery at Harvard surgery community, and oral presentations: nine in basic Duke University, whose topic was make connections that may spark science and nine in clinical/health “Standing on the Shoulders of future collaborations,” says services research. First and second Giants: One Surgeon’s Adventures Dr. Chaikof. prizes were awarded for the best as a Physician-Scientist.” The first year, 150 abstracts oral presentations in each category, “Harvard Surgery Research were submitted; in 2021, the total and winners were announced at Day provides a great showcase reached 190 abstracts. Trainees the event. of research projects across the at all levels, not just residents, Based this year at BIDMC, Harvard surgical community and a are encouraged to participate, the 2021 organizing committee unique opportunity to connect with including clinical fellows, medical members were: Louis Chu, MD, other scientists,” says recent BIDMC or graduate students, and PhD Christiane Ferran, MD, PhD, and vascular surgery graduate Patric postdoctoral fellows. Jennifer Wilson, MD, MPH, BIDMC; Liang, MD. Dr. Liang’s oral abstract Dario Fauza, MD, PhD, and Tom on the outcomes of transcarotid Harvard Surgery Research Jaksic, MD, PhD, Boston Children’s artery revascularization compared Day Visiting Professors Hospital; Erika Rangel, MD, and to carotid endarterectomy tied Quoc-Dien Trinh, MD, Brigham and for second place in the clinical/ 2012: Thomas Krummel, MD Women’s Hospital; and Genevieve health services research category. 2013: Yuman Fong, MD Boland, MD, PhD, and Motaz “I continue to be impressed year 2014: Michael Longaker, MD, MBA 2015: John Birkmeyer, MD Qadan, MD, PhD, Massachusetts after year by the breadth and 2016: Timothy Billiar, MD General Hospital. novelty of the research projects 2017: Melina Kibbe, MD Since the event was held being presented, and I am grateful 2018: Gail Besner, MD virtually this year, there was to have had the opportunity to 2019: Steven Libutti, MD no poster session, which is present our project this year.” 2021: E. Shelley Hwang, MD, MPH always a highlight of the day. bidmc.org/surgery Inside Surgery | Summer 2021 — Page 22 HOME << | >> IN MEMORIAM

The Department of Surgery mourns the loss of two longtime, beloved colleagues: William C. DeWolf, MD, and Clinton Koufman, MD.

William C. DeWolf, MD Award and selection as an Dr. DeWolf joined BIDMC in 1984 American Urological Association and served as Chief of Urology Scholar. Dr. DeWolf was president from 1988 until his retirement in of the National Urologic Forum 2019. Dr. DeWolf was the BIDMC and served on the editorial board Distinguished Professor of Surgery of Urology, one of the leading at Harvard Medical School. academic urologic journals. Born and raised in Illinois, In 2007, an endowed chair Dr. DeWolf attended an advanced at Harvard Medical School—the seven-year medical school program Janet & William DeWolf Professor at Northwestern University, from of Surgery/Urology at Harvard which he graduated in 1967. Medical School—was established in Dr. DeWolf completed his residency his honor. The chair is held by at the University of Minnesota, and Dr. DeWolf’s successor, Aria Olumi, later completed a fellowship in MD, Chief of Urologic Surgery. transplantation at the University of Dr. DeWolf was a role model Minnesota and a research fellowship and mentor to scores of faculty Dr. William C. DeWolf at Dana-Farber Cancer Institute. and trainees and provided In addition to serving as Chief of compassionate care to countless his children Steven and Julia; two Urology and Director of the Urologic patients. In addition to his family, grandchildren; and his siblings Research Laboratories at BIDMC, Dr. DeWolf loved Boston sports, Cherris and Craig. Dr. DeWolf’s illustrious 35-year career classical music, and trips to Maine. Contributions in memory of as a surgeon-scientist reflects a long Dr. DeWolf died on May 24, Dr. DeWolf may be made to the list of achievements that include 2021, following a long, valiant battle William C. DeWolf, MD Visiting a National Institutes of Health with pancreatic cancer. He leaves Professorship Endowment Fund Research Career Development behind his wife of 55 years, Janet; (bidmcgiving.org/dewolf).

Clinton Koufman, MD was a role model for decades of Dr. Koufman was a devoted surgical trainees. physician, husband, father, Dr. Koufman was predeceased grandfather, and great-grandfather by his wife, Laurel, and is survived by who practiced at BIDMC for more his children, Ann Koufman-Frederick, than 50 years. After graduating from PhD, Victor Koufman, and Stephanie Brookline High School, William and Koufman; seven grandchildren, Mary College, and Boston University and four great-grandchildren. School of Medicine, Dr. Koufman One of Dr. Koufman’s grandsons, completed his residency in general Steven Koufman Leckie, MD, is an surgery at BIDMC, interrupted by orthopedic surgeon at Beth Israel two years of service in the U.S. Deaconess Hospital-Plymouth. Air Force. Dr. Koufman touched the lives Dr. Clinton Koufman with his wife, Laurel. Dr. Koufman was in private of dozens of family members and practice at BIDMC for his entire friends, hundreds of students and host a post-pandemic celebration career until his retirement in 2008. colleagues, and thousands of of Dr. Koufman’s life at a later date. Late in his career, he transitioned patients. He loved books, swimming, Contributions in memory of from general surgery to specialize and travel. Dr. Koufman died Dr. Koufman may be made to in breast cancer surgery. He served peacefully at home, surrounded by the Clinton and Joseph Koufman as president of the medical staff, his children, on December 21, 2020 Award Fund at Beth Israel and because of his technical skill, at the age of 91. A private burial was Deaconess Medical Center humor, and warmth, Dr. Koufman held in December. The family may (bidmc.org/givenow). bidmc.org/surgery Inside Surgery | Summer 2021 — Page 23 HOME <<

Beth Israel Deaconess Medical Center Department of Surgery, LMOB-9C 110 Francis Street Boston, MA 02215

Gift Supports Pancreatic Cancer Research

his year, more than 60,400 adults in the United to identify biomarkers based on TStates will receive a diagnosis of pancreatic thousands of tumor samples. cancer. Sadly, only one in ten will still be alive in five Using this AI platform, Berg also years, taken by a type of cancer that in addition to developed a new cancer drug being particularly aggressive often eludes detection that is now ending phase 2 clinical trials for patients with metastatic until it is too late for treatment to be effective. pancreatic cancer. Determined to turn the tide on pancreatic cancer, “Our partnership has advanced a true precision in 2014 the Boston-area biotechnology company Berg medicine approach to diagnosing and treating Health partnered with BIDMC and other collaborators pancreatic cancer,” says Niven R. Narain, PhD, President in the multi-national Pancreatic Cancer Research Team and Chief Executive Officer of Berg. “Dr. Moser, a partner in an initiative called Project Survival®. Project Survival who is forward-thinking in clinical innovation, makes the is led by surgical oncologist A. James Moser, MD, Co- perfect collaborator on Berg’s technology to address one Director of both the BIDMC Pancreas and Liver Institute of the most dire unmet needs in medicine.” and the BIDMC Pancreatic Cancer Research Program. In 2006, Dr. Narain co-founded the company with Board Chair and Silicon Valley venture capitalist and commercial real estate developer, Carl E. Berg. Mr. Berg “Our partnership has advanced a is passionate about improving health by using patient true precision medicine approach biology and AI as the basis for developing diagnostics to diagnosing and treating and drugs, and has supported Berg’s leading-edge pancreatic cancer.” Interrogative Biology® platform development, which has been the main driver of analyses to Project Survival. —Niven R. Narain, PhD This spring, in a further act of generosity, Berg President and Chief Executive Officer, Berg Health Health made a philanthropic gift of $270,000 to support Dr. Moser’s ongoing pancreatic cancer biomarker research. “The sustained commitment to pancreatic The goal of Project Survival, which has been cancer research by Mr. Berg and Dr. Narain over many supported since its inception by a $5 million grant from years has been extraordinary,” says Dr. Moser. “Thanks Berg, is to identify and validate prognostic biomarkers that will enable clinicians to not only diagnose pancreatic to their vision, support, and generosity, we are that cancer early, but also to determine which treatments much closer to our shared goal of dramatically are most likely to be effective in individual patients. Berg reducing deaths from pancreatic cancer through employs its powerful artificial intelligence (AI) platform early detection and targeted treatment.”

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