De Vlaamse Aidspionier En Ondernemer Rudi Pauwels Is De

Total Page:16

File Type:pdf, Size:1020Kb

De Vlaamse Aidspionier En Ondernemer Rudi Pauwels Is De ZAKEN PIONIERGENOMINEERDE 4: RUDI PAUWELS IN AIDSPREVENTIE EN ZIEKTEDETECTIE De Vlaamse aidspionier en RUDI PAUWELS “Ik heb al veel ondernemer Rudi Pauwels is gedaan in mijn leven, maar over wat we de vader van een revolutionair hier hebben gedaan, kan je zeggen dat het minilab dat snel een breed not often done is.” gamma van ziektes kan detecteren. Het leverde hem een tweede nominatie voor Trends Manager van het Jaar op. BERT LAUWERS e 54-jarige Pauwels lanceerde midden de jaren negentig de hiv-specialist Tibo- tec-Virco. Daarmee lag hij aan de basis van drie van ’s werelds meest gebruikte en succesvolste aidsremmers. Nadat hij Tibotec-Virco in 2002 had verkocht aan Dde Amerikaanse farmareus Johnson & Johnson, trok Pauwels met zijn gezin naar Zwitserland om er tijdens een sabbatical nabij het meer van Genève te herbronnen. Daar kiemde de zin voor een nieuw baanbrekend medisch avon- tuur, dat in 2007 uitmondde in de lancering van Biocartis. Met zijn nieuwe initiatief wilde de CEO en voorzitter van Biocartis een mobiel lab ontwik- kelen dat op basis van bloed, speeksel of tumor- weefsel snel een breed gamma van ziektes, of zelfs de aanleg tot ziektes, in een zeer vroeg stadium kan opsporen en zo veel erger kan voorkomen voor patiënten. Biocartis focust intussen op de detectie van kankers. Het minilab, Idylla geheten, is pas gelanceerd, na zeven jaar ontwikkeling en investeringen. Het EMY ELLEBOOG 78 30 OKTOBER 2014 | WWW.TRENDS.BE eerste toestel is de deur uit, naar een niet sche uitdagingen, maar ook de financie- nader genoemd Belgisch universitair zie- “De hiv-remmers ring, de snelle uitbouw, en het op heel kenhuis. De verwachtingen zijn hoog- korte tijd samenbrengen van mensen met gespannen, ook al omdat het toestel de van Tibotec-Virco verschillende culturen en achtergron- uitgaven in de gezondheidszorg mee den die verbiocartiseerd moeten worden”, onder controle moet kunnen houden. zijn wereldwijd zegt Pauwels. Samen met financieel direc- “Dit past volledig in de gepersonali- beschikbaar. teur Hilde Windels dokterde hij dit jaar seerde geneeskunde”, zegt Pauwels. “Bio- ook een nieuwe structuur voor de prille farmabedrijven ontwikkelen wereldwijd Met Biocartis groep uit. Die herstructurering omvat honderden nieuwe therapieën tegen kan- ook de overname van het Gentse bio- ker. Wij kunnen met onze testen bepa- kan ik niet voor techbedrijf Pronota. len welk geneesmiddel zal werken bij een patiënt. Dat is belangrijk om de juiste the- minder gaan” Vaandeldrager van de biotech rapie te kiezen en nodeloze uitgaven voor Pauwels, die eerder mee aan de oor- een of ander duur product te vermijden. sprong lag van het beursgenoteerde Bel- Dit gaat ook in tegen het gangbare beeld gisch-Nederlandse biotechbedrijf Gala- dat de ontwikkeling van al die nieuwe van de KU Leuven, heeft intussen de pagos, is uitgegroeid tot een onbetwiste geneesmiddelen de gezondheidszorg activiteiten van Biocartis grotendeels vaandeldrager van de Vlaamse biotech- onbetaalbaar zal maken. Het is net omge- geconcentreerd in de hem zeer ver- sector. Zijn belang voor de sector werd keerd.” trouwde vroegere gebouwen van Tibo- dik in de verf gezet toen hij in 2010 dank- Pauwels droomt er al lang van het tec-Virco in Mechelen. Die stonden leeg zij de inspanningen van enkele oude diagnosetoestel in een later stadium ook sinds de verhuizing van het bedrijf naar bekenden uit de biotechsector en van de aan te wenden voor een brede waaier van de campus van Janssen Pharmaceutica, overheid kon worden overtuigd om in toepassingen. Zo zou Idylla ooit kunnen een andere dochter van Johnson & Vlaanderen het productieapparaat van worden gebruikt in luchthavens, cruise- Johnson, in Beerse. “In 36 maanden heb- Biocartis uit te bouwen. Voor de Vlaamse schepen of zelfs supermarkten. Pauwels ben we hier een bedrijf van A tot Z uit- biotechsector was die terugkeer van de ziet bovendien potentieel in de voe- gebouwd. We hebben niet alleen een verloren zoon toen een opsteker van for- dingsindustrie of bij milieutesten. product ontwikkeld met de allerhoog- maat. Om de lancering van Idylla te finan- ste normen, maar ook een hele produc- Het spectaculaire parcours van Bio- cieren, haalde Biocartis recentelijk nog tie-infrastructuur en commerciële infra- cartis heeft al ver buiten de landsgren- 64,5 miljoen euro op. Sinds de start van structuur, en we zijn van een tiental zen indruk gemaakt. Zo werd het bedrijf het bedrijf verzamelde Pauwels daarmee mensen naar 194 gegroeid.” twee jaar geleden al door het Wereld Eco- bij investeerders al bijna een kwart mil- “Ik heb al veel gedaan in mijn leven, nomisch Forum bekroond tot technolo- jard euro. De trouwe believers in Pauwels maar over wat we hier hebben gedaan, giepionier. En de bekendheid zal een forse zijn niet van de minsten. Het gaat om kan je zeggen dat het not often done is”, duw in de rug krijgen wanneer Biocartis onder anderen de familie Colruyt, de zei Pauwels eerder in Trends. Over vijf zoals verwacht volgend jaar naar de beurs familie van Janssen Pharmaceutica-stich- jaar moet Biocartis een revenue engine trekt om Idylla zo snel mogelijk wereld- ter Paul Janssen, ex-bouwaannemer Luc zijn die niet meer afhankelijk is van wijd te kunnen uitrollen. Verelst en Rudi Mariën, de voormalige externe financiering, stelt de doctor in “We hebben maar weinig tijd in dit sterke man van Innogenetics. Ook de de farmaceutische wetenschappen, die leven en in die korte tijd proberen we iets Vlaamse investeringsmaatschappij PMV terugblikt op “een heel groot jaar”. “Er te realiseren”, zei Pauwels eerder in en het Vlaams overheidsfonds voor Inno- waren niet alleen de grote technologi- Trends. “Ik steek er mijn energie, tijd en vatie IWT hebben zich achter het geld niet in om in de periferie het bedrijf geschaard, net als Johnson kader op te vullen. Vandaag zijn de & Johnson en het Nederlandse Phi- BIOCARTIS SA (IFRS) hiv-remmers van Tibotec-Virco lips. Sinds de recente kapitaalronde wereldwijd beschikbaar. Met Bio- is ook het Japanse Hitachi Chemi- In miljoen euro 2013 2012 2011 cartis kan ik niet voor minder gaan.” cal aan boord gekomen. Inkomsten 12,1 6,6 10,3 De recente ontwikkelingen hebben Nettoresultaat -35,6 -44,4 -33,1 zijn ambitie met het bedrijf alleen Een groot jaar Vrije kasstroom -44,9 -48,9 -32,8 maar aangezwengeld. “Ik ben nu Pauwels, die in 1984 begon als Kortetermijnschuld 13,4 13,8 12,3 nog meer overtuigd en gepassio- onderzoeker aan het Rega-instituut Personeel (einde jaar) 175 145 79 neerd.” z WWW.TRENDS.BE | 30 OKTOBER 2014 79.
Recommended publications
  • Biomérieux and Biocartis Sign Strategic Partnership in Molecular Diagnostics
    bioMérieux and Biocartis Sign Strategic Partnership in Molecular Diagnostics Co-development of assays and co-distribution of a fully integrated molecular platform due for launch in 2012 bioMérieux gains exclusive rights in microbiology bioMérieux takes equity stake in Biocartis Marcy l’Etoile (France) and Lausanne (Switzerland) – November 4, 2010 — bioMérieux and Biocartis announced today that they have entered into a strategic agreement to co-develop assays on Biocartis’ fully integrated molecular diagnostics system, which the two companies will co-distribute starting in 2012. Under the agreement, bioMérieux will have worldwide exclusive rights to develop and commercialize microbiology assays on the platform. It will also have access to the platform for certain oncology and theranostics assays. bioMérieux has taken a €9 million equity stake in Biocartis. Biocartis has continued to successfully develop its molecular diagnostics platform, which was acquired from Philips earlier this year. The platform now fully integrates all the steps of a multiplexed molecular assay, from sample-in to data- out, in a sealed disposable cartridge, which avoids any contamination risk. Providing rapid results, the system is able to perform complex tests on a wide variety of samples, including oncology assays on tissue. The Biocartis platform does not require molecular biology experience or infrastructure with highly skilled technicians, and involves only 1-2 minutes hands-on time. Adapted to both small and large labs, the platform is fully scalable and allows random access use. bioMérieux, the world leader in microbiology, will enhance the Biocartis platform’s broad menu with an exclusive line of tests for healthcare-associated infections and sepsis.
    [Show full text]
  • Invitation to Annual Shareholders' Meeting
    PRESS RELEASE REGULATED INFORMATION 10 April 2018, 07:00 CEST Invitation to Annual Shareholders’ Meeting Biocartis to propose new board composition Mechelen, Belgium, 10 April 2018 – Biocartis Group NV (the ‘Company’ or ‘Biocartis’), an innovative molecular diagnostics company (Euronext Brussels: BCART), has the honor to invite its shareholders, warrant holders, directors and statutory auditor to its annual shareholders' meeting that will be held on Friday 11 May 2018 at 2:00 p.m. CEST (‘AGM’) at the offices of the Company at Generaal de Wittelaan 11B, 2800 Mechelen, Belgium. The agenda of the AGM includes the proposal for a new board composition based on the appointment of five new independent board members and the re-appointment of three board members whose current mandates will expire at the closing of the AGM. The proposed board composition will allow for a transition towards a board of directors consisting predominantly of independent directors. Subject to the AGM approving the proposed resolutions, the board of directors will be composed as follows as from the closing of the AGM: Five new independent board members: CRBA Management BVBA, represented by Christian Reinaudo (candidate chairman of the board), Ann-Christine Sundell, Harry Glorikian, CLSCO BVBA, represented by Leo Steenbergen, and Luc Gijsens BVBA, represented by Luc Gijsens. Additional information on the proposed new board candidates is included in the explanatory note prepared by the board of directors which can be found on the Company’s website. Four existing board members: Herman Verrelst (CEO) and the re-appointment of three board members, i.e. Peter Piot (independent director), Hilde Windels BVBA, represented by Hilde Windels (non-executive director) and Roald Borré (non-executive director).
    [Show full text]
  • Praesens Foundation, Institut Pasteur, Institut Pasteur De Dakar, University of Nebraska Medical Center, Twist Bioscience Consortium Win Prix Galien Medstartup Award
    Praesens Foundation, Institut Pasteur, Institut Pasteur de Dakar, University of Nebraska Medical Center, Twist Bioscience Consortium Win Prix Galien MedStartUp Award October 24, 2019 -- Consortium Developed an Integrated Solution for Better Preparedness and Faster Response to Outbreaks and Epidemics in High-Risk Areas -- BRUSSELS & PARIS & SOUTH SAN FRANCISCO, Calif. & OMAHA, Neb.--(BUSINESS WIRE)--Oct. 24, 2019-- The Praesens Foundation, the Institut Pasteur, the Institut Pasteur de Dakar, University of Nebraska Medical Center and Twist Bioscience Corporation (NASDAQ: TWST) today announced that the consortium is the winner of the Prix Galien MedStartUp award in the category: 'Best Collaboration Dedicated to the Developing or Underserved Populations Worldwide'. The consortium works together to develop, quantify and scale up a range of innovative solutions on the continent of Africa to ensure better preparedness and response to infectious disease outbreaks. This includes assays to rapidly identify pathogens developed for and by low and middle income countries that are not necessarily addressed by the traditional diagnostic players and will benefit the communities that need it most. “Past and recent disease outbreaks of Ebola, SARS, MERS-CoV, Zika and Dengue, have shown that infectious diseases continue to affect many lives while also representing social, economic, and national security threats that can quickly evolve into global health crises1, causing major human suffering and imposing enormous economic damage,” said Dr. Rudi Pauwels,
    [Show full text]
  • Meeting Report: 26Th International Conference on Antiviral Research Q
    Antiviral Research 100 (2013) 276–285 Contents lists available at ScienceDirect Antiviral Research journal homepage: www.elsevier.com/locate/antiviral Review Meeting report: 26th International Conference on Antiviral Research q R. Anthony Vere Hodge Vere Hodge Antivirals Ltd, Old Denshott, Leigh, Reigate, Surrey, UK article info abstract Article history: The 26th International Conference on Antiviral Research (ICAR) was held in San Francisco, California from Received 2 August 2013 May 11 to 15, 2013. This article summarizes the principal invited lectures at the meeting. The opening Accepted 8 August 2013 symposium on the legacy of the late Antonín Holy´ included presentations on his pioneering work with Available online 21 August 2013 nucleotide analogs, which led to the development of several antiviral drugs including tenofovir. This drug has transformed the treatment of HIV infection and has recently become the first-line therapy for chronic Keywords: hepatitis B. The Gertrude Elion Award lecturer described the anti-HIV activities of the CCR5 inhibitor Human immunodeficiency virus cenicriviroc and the reverse transcriptase inhibitor festinavirÒ, and also reviewed the evaluation of bio- Hepatitis B degradable nanoparticles with adjuvant activity. The William Prusoff Award winner reported on the cre- Hepatitis C Herpesviruses ation of NAOMI, a computer model with 21 enzymes to predict the activity of nucleoside analogs against Antiviral therapy hepatitis C virus (HCV). Other invited lecturers discussed the development of countermeasures against severe dengue and the potential of RNA virus capping and repair enzymes as drug targets. Topics in the clinical symposium included the current status of the anti-HCV compounds sovaprevir, ACH-3102, miravirsen and ALS-2200; the evaluation of single-tablet regimens for HIV infection; and the investiga- tion of cytomegalovirus resistance to CMX001.
    [Show full text]
  • Johnson & Johnson to Acquire Tibotec-Virco
    Johnson & Johnson to Acquire Tibotec-Virco NEW BRUNSWICK, N.J., March 22 /PRNewswire-FirstCall/ -- Johnson & Johnson today announced it has signed a definitive agreement to acquire all of the assets of Tibotec-Virco NV, a privately-held biopharmaceutical company focused on developing anti-viral treatments, with several promising compounds in development for the treatment of infectious diseases including HIV. The transaction is valued at approximately $320 million in cash and debt. Johnson & Johnson is expected to incur a one-time charge of approximately $145 million, or $0.05 per share, upon closing, reflecting the write-off of in-process research and development costs. The transaction is anticipated to close in the second quarter of 2002 subject to customary closing conditions and regulatory approvals. Excluding one-time charges, the acquisition is not expected to impact earnings for 2002 or 2003. "Tibotec-Virco will provide a good strategic fit with our current pharmaceutical research and development operations," said Dr. Per Peterson, Chairman, Research & Development for the pharmaceuticals group of Johnson & Johnson. "By combining Tibotec-Virco's expertise with our own research and development activities, we will expand our drug discovery and development capabilities, particularly in the field of anti-viral therapies." Headquartered in Mechelen, Belgium, Tibotec-Virco applies the latest techniques in ultra-high throughput screening, pharmacogenomics, molecular biology and artificial intelligence to discovering and developing new drugs. The company has drug discovery and development programs focusing on potential new drugs that are active against drug-resistant strains of HIV including two products in early clinical development. Tibotec-Virco also has early stage research programs concentrating on the development of treatments for hepatitis C and other infectious diseases.
    [Show full text]
  • Life Sciences 2010.Key
    LIFE SCIENCES FLANDERS Prof. Dr. Ann Van Gysel, Managing Director FlandersBio FLANDERS, BELGIUM Centrally Located Biotech hub SUCCESSFUL BIOTECH HUB • World renowned research centers, universities and hospitals • 143 life sciences companies with biotech activities • 118 conduct innovative R&D • Flanders ranks no 2 in Europe • Total market cap, stock listed biotech companies • Flanders Ranks no 1in Europe • Annual life sciences convention >900 participants LIFE SCIENCES AREAS • Medical Biotech - focus on healthcare, from diagnostics to therapeutics • Plant Biotech - largest R&D hub in Europe, from molecular breeding to GMOs • Industrial Biotech - focus on bioprocessing, from enzymes to biofuels and food STRONG IN R&D • Innovative research • Strong life sciences companies network • Big in Biopharma • Clinical excellence INNOVATIVE RESEARCH • High quality universities • Excellent research institutes, focus on life sciences • VIB [world class biotech research] • IMEC [focus on nanotechnology] • CMI [translational medicine] Ind. Products Health care Agro & Food R&D provider Tech provider 143 BIOTECH COMPANIES 12 24 21 15 64 Ind. Products Health care Agro & Food R&D provider 13.000 Tech provider EMPLOYEES IN 384 R&D 1.163212 >30.000 in total 4.648 6.652 BELGIUM, HOME TO ... • Pharmaceutical companies • 5% of the top-100 drugs are developed in Belgium • Per capita the highest number of drugs in development • Total production: 5.2 billion euro • Total export value: 34 billion euro source: pharma.be CLINICAL EXCELLENCE • Dense medical network •
    [Show full text]
  • Resistance Analyses in HIV Infected Patients with a History of Multiple
    Sex Transm Inf 2001;77:449–452 449 Sex Transm Infect: first published as 10.1136/sti.77.6.449 on 1 December 2001. Downloaded from Resistance analyses in HIV infected patients with Original a history of multiple antiretroviral treatment article regimens Andreas Plettenberg, Dirk Albrecht, Thore Lorenzen, Volker Paech, Heiko Petersen, Thomas Fenner, Thomas Meyer, Rüdiger Arndt, Kurt Hertogs, Rudi Pauwels, Thomas Weitzel, Albrecht Stoehr Objective: To assess HIV-1 isolate based resistance profiles from extensively pretreated patients and eVects of a resistance guided switch of antiretroviral therapy. Methods: In a prospective study phenotypic and genotypic resistance analyses were performed on HIV infected individuals with failure of the current therapy and history of at least three anti- retroviral regimens. Antiretroviral therapy was changed according to the results. Viral load and CD4 lymphocyte counts were measured at baseline, after 10 (SD 2), and 24 (2) weeks. Results: All patients (n=52) failed their actual regimen. Currently versus ever previously taking the specific drug, resistance associated mutations and phenotypic resistance to AZT and 3TC were found in over 80% of individuals; resistance to DDI and D4T was detected in less than 10% of cases. A resistance guided switch of therapy was followed by a median decrease of viral load of 0.5 log10 units after 24 weeks. Individuals resistant to two or more drugs compared with patients with resistance to less than two drugs of ongoing treatment, were switched to a regimen contain- ing DDI, D4T, and a PI or NNRTI. After 10 (SD 2) weeks viral load decrease was pronounced in patients with resistance to at least two drugs in the previous regimen.
    [Show full text]
  • Janssen Diagnostics and Biocartis Announce Launch of Influenza-Respiratory Virus Panel on the Idylla™ Platform
    PRESS RELEASE Janssen Diagnostics and Biocartis announce launch of Influenza-Respiratory Virus Panel on the Idylla™ platform Mechelen and Beerse, Belgium, 30 November 2015 - Janssen Diagnostics, part of the Johnson & Johnson family of companies (NYSE: JNJ) and Biocartis (Euronext Brussels: BCART), an innovative molecular diagnostics company, today announced the launch of their first infectious disease test on the Idylla™ platform. The Idylla™ Respiratory IFV-RSV Panel has been developed by Janssen Diagnostics and is intended for the detection of various strains of Influenza Virus (IFV) and Respiratory Syncytial Virus (RSV). The Idylla™ Respiratory IFV-RSV Panel received CE-IVD marking on 18 November 2015 and is being launched for commercial use in Europe and other geographies recognising the CE-mark. Janssen Diagnostics has appointed Biocartis as co-exclusive worldwide distributor of the test. Respiratory viruses are one of the most important causes of morbidity and mortality throughout the world1 with the influenza virus killing at least 50 million and up to 100 million people in the last century alone2. The majority of diagnostic tests currently used for this market are rapid immunoassays which are chosen due to their low cost and convenience. However, one of the key downsides of these rapid tests is their poor sensitivity. Negative samples are typically re-tested in a central lab with a more sensitive molecular test, delaying time-to-result by many hours. The new Idylla™ Respiratory IFV-RSV Panel, running on the Idylla™ platform, combines in one single product the speed of rapid tests with the quality and sensitivity standards of central lab tests.
    [Show full text]
  • PDF Version of This Page
    About this Report Annual overview 2013 Janssen Global Public Health founded Launch of INVOKANA® (canagliflozin), IMBRUVICA™ (ibrutinib), OLYSIO™ (simeprevir) Dr. Paul Stoffels in top 25 of the biopharmaceutical sector Janssen-Cilag adjusts organization in Belgium and the Netherlands Janssen wins Supply Chain Award 2013 Join forces in the fight against brain diseases Economic trade mission in India Open doors for the first time in many years 10 years the difference for people with HIV Animal rights activists protest Dr. Koen Andries celebrated First Lifetime Achievement Award FIT Start-up of combined heat and power plant House of Work Ability European Medical Information Framework (EMIF) Pillcoach Labyrinth Psychotica HepCoach Janssen Global Public Health founded In 2013 Janssen announced the creation of Janssen Global Public Health (GPH), a major step in the organization’s commitment to finding solutions, together with others, which may turn the tide of global healthcare and offer an answer to the medical needs of, among others, the most vulnerable regions. The new structure joins all efforts made by Janssen in the field of development and availability of innovative medicines. Our goal is to address seemingly intractable health challenges in new and unexpected ways. Janssen GPH mainly focuses on diseases which are a heavy burden for countries with limited resources and emerging markets. Launch of INVOKANA® (canagliflozin), IMBRUVICA™ (ibrutinib), OLYSIO™ (simeprevir) In 2013 three new products were launched in the United States and several other In addition, the FDA approved IMBRUVICA™ (ibrutinib) capsules for patients with countries. In March 2013 Janssen announced the approval by the US Food and mantle cell lymphoma (MCL).
    [Show full text]
  • Life Sciences
    DEZE THEMABIJ LAGE WORDT GEPUBLICEERD DOOR MEDIAPLANET EN VALT NIET ONDER DE VERANTWOORDELIJ KHEID VAN DE REDACTIE VAN DE STANDAARD FEBRUARI 2019 WWW.IEDEREENINNOVEERT.BE Life Sciences WAR FOR TALENT P06 Zoektocht naar de juiste profi elen. HUMAN RESOURCES P07 Rudi Pauwels: Focus op outsourcing en projectmatig werken. "De gezondheidssector INNOVATIEPLATFORM P10 heeft een universele Brug tussen wetenschap en industrie. roadmap nodig." © FOTO: PRIVÉ© FOTO: Experten van Van Lanschot Kempen in life sciences en private banking vanlanschot.be kempen.com 2 ❘ WWW.IEDEREENINNOVEERT.BE MEDIAPLANET Infrastructuur Nieuwe indeling van laboratoria trekt jonge onderzoekers aan en stimuleert innovatie. P13 De Belgische biotech Precisiegeneeskunde Jo Vandesompele legt VOORWOORD uit hoe diagnoses via barst uit zijn voegen liquid biopsies gesteld kunnen worden met een minimaal invasieve De toepassingsgebieden van biotech worden niet alleen procedure. talrijker, maar binnen eenzelfde domein bewijzen steeds P15 vaker meerdere vormen van biotech hun grote waarde. Willem Dhooge en Pascale Engelen, Co-General Managers van flanders.bio, geven duiding bij deze trend. www.iedereeninnoveert.be Pascale Willem Dhooge Engelen Co-General Co-General Manager Manager flanders.bio flanders.bio De lifesciencessector zet steeds meer in op preventie bij wondzorg. Ontdek de innovaties op onze website. raditioneel telt België een aan- Vlaamse Overheid, bedrijven en koepelor- tal toonaangevende industriële ganisaties ondersteunt bedrijven bij het sectoren, zoals de chemische en inzetten van biotech, medische technologie farmaceutische sector en de voe- of digitale technologieën voor de ontwikke- dingsindustrie. Ook in de nieuwe ling van nieuwe gezondheidsoplossingen. LIFE SCIENCES ❘ FEBRUARI 2019 Thoogtechnologische sectoren gooit ons land in Europa en op wereldvlak hoge ogen.
    [Show full text]
  • Annual Report 2015 2
    Biocartis Annual Report 2015 2 Sooner “or later, we are all patients.” RUDI PAUWELS, FOUNDER AND CEO BIOCARTIS 2015 Highlights 05 4. Remuneration report 76 76 Interview Biocartis Chairman Rudi Mariën 07 4.1. Remuneration policy and CEO & Founder Rudi Pauwels​​ 4.2. Remuneration of Directors 76 Disclaimer and other information​​​​​​ 09 4.3. Remuneration of members of the 77 executive team 80 1. Business section 10 4.4. Relative weighting of each component of the remuneration 1.1. About Biocartis Group 12 4.5. Characteristics of the stock options 80 1.2. Risks related to our business​​​​​ 18 4.6. Changes to the remuneration policy 82 1.3. Review 2015​​​​​​​ 25 4.7. Remuneration policy for the next two 83 1.4. Biocartis as an organisation​​​​​ 35 financial years (2016-2017) 3 1.5. Activities 39 4.8. Main contractual conditions 83 2. The Biocartis share 52 5. Consolidated annual accounts 86 2.1. Outstanding shares and share capital 52 5.1. Consolidated financial statements as of 86 and for the years ended 31 December 2.2. Share performance​​​​​​ 53 2015 and 2014 2.3. Trading volume 53 5.2. Notes to the consolidated financial 91 2.4. Shareholders 54 statements 2.5. Analyst coverage 56 2.6. Financial calendar 56 6. Statutory Annual Accounts 140 6.1. Abbreviated statutory annual accounts 140 2.7. Investor relation details 56 6.2. Activity Biocartis Group NV 140 6.3. Income statement and balance sheet 140 3. Corporate Governance 60 Biocartis Group NV 3.1. Introduction 60 6.4. Discussion of statutory accounts 141 3.2.
    [Show full text]
  • Belgian Events
    Newsletter of the Belgian Embassy in London Belgian Events June 2011 The recently opened ‘Museum aan de Stroom’ (MAS) forms part of a regeneration project in Antwerp’s port Royal news Page 2 Royal Wedding Some 40 ‘crowned heads’ attended the Royal Marriage of Prince William and Catherine Middleton on 29 April. The Belgian Royal Household was represented by HRH Crown Prince Philippe and HRH Princess Mathilde. HRH Crown Prince Philippe and HRH Princess Mathilde at Westminster Abbey Belgian Embassy, 17 Grosvenor Crescent, London SW1X 7EE E-mail: [email protected] Website: www.diplomatie.be/london Editor: Kris Dockx Reactions and contributions by outsiders are welcome Political news Page 3 Belgian elected head of global transport policy body Belgian Carole Coune, 42, has been chosen to succeed Ireland’s Jack Short as the next Secretary General of the International Transport Forum at the OECD. At their annual summit in Leipzig in May, transport ministers from 52 member countries chose Coune to succeed Short as the head of the Paris-based intergovernmental organisation. The International Transport Forum provides a global platform for transport policy issues. It acts as a thinktank for member countries and organises an annual summit, at which ministers debate strategic issues of the sector with business leaders, top academics and representatives of civil society. Carole Coune earned her stripes with the Belgian Na- tional Railway, where, amongst others, she was Secre- tary to the Management Board and led the Department of International Affairs. After several years’ experience in the policy cell of the Belgian Minister for Transport, Coune became Director General for Land Transport at the Belgian Ministry of Transport in 2005.
    [Show full text]