PROGRAM (Updated 5 July, 2016)
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New Challenges and Opportunities for Innovation Peter Piot, London
Professor Peter Piot’ Biography Baron Peter Piot KCMG MD PhD is the Director of the London School of Hygiene & Tropical Medicine, and the Handa Professor of Global Health. He was the founding Executive Director of UNAIDS and Under Secretary-General of the United Nations (1995-2008). A clinician and microbiologist by training, he co-discovered the Ebola virus in Zaire in 1976, and subsequently led pioneering research on HIV/AIDS, women’s health and infectious diseases in Africa. He has held academic positions at the Institute of Tropical Medicine, Antwerp; the University of Nairobi; the University of Washington, Seattle; Imperial College London, and the College de France, Paris, and was a Senior Fellow at the Bill & Melinda Gates Foundation. He is a member of the US National Academy of Medicine, the National Academy of Medicine of France, and the Royal Academy of Medicine of his native Belgium, and is a fellow of the UK Academy of Medical Sciences and the Royal College of Physicians. He is a past president of the International AIDS Society and of the King Baudouin Foundation. In 1995 he was made a baron by King Albert II of Belgium, and in 2016 was awarded an honorary knighthood KCMG. Professor Piot has received numerous awards for his research and service, including the Canada Gairdner Global Health Award (2015), the Robert Koch Gold Medal (2015), the Prince Mahidol Award for Public Health (2014), and the Hideyo Noguchi Africa Prize for Medical Research (2013), the F.Calderone Medal (2003), and was named a 2014 TIME Person of the Year (The Ebola Fighters). -
Biomérieux and Biocartis Sign Strategic Partnership in Molecular Diagnostics
bioMérieux and Biocartis Sign Strategic Partnership in Molecular Diagnostics Co-development of assays and co-distribution of a fully integrated molecular platform due for launch in 2012 bioMérieux gains exclusive rights in microbiology bioMérieux takes equity stake in Biocartis Marcy l’Etoile (France) and Lausanne (Switzerland) – November 4, 2010 — bioMérieux and Biocartis announced today that they have entered into a strategic agreement to co-develop assays on Biocartis’ fully integrated molecular diagnostics system, which the two companies will co-distribute starting in 2012. Under the agreement, bioMérieux will have worldwide exclusive rights to develop and commercialize microbiology assays on the platform. It will also have access to the platform for certain oncology and theranostics assays. bioMérieux has taken a €9 million equity stake in Biocartis. Biocartis has continued to successfully develop its molecular diagnostics platform, which was acquired from Philips earlier this year. The platform now fully integrates all the steps of a multiplexed molecular assay, from sample-in to data- out, in a sealed disposable cartridge, which avoids any contamination risk. Providing rapid results, the system is able to perform complex tests on a wide variety of samples, including oncology assays on tissue. The Biocartis platform does not require molecular biology experience or infrastructure with highly skilled technicians, and involves only 1-2 minutes hands-on time. Adapted to both small and large labs, the platform is fully scalable and allows random access use. bioMérieux, the world leader in microbiology, will enhance the Biocartis platform’s broad menu with an exclusive line of tests for healthcare-associated infections and sepsis. -
Invitation to Annual Shareholders' Meeting
PRESS RELEASE REGULATED INFORMATION 10 April 2018, 07:00 CEST Invitation to Annual Shareholders’ Meeting Biocartis to propose new board composition Mechelen, Belgium, 10 April 2018 – Biocartis Group NV (the ‘Company’ or ‘Biocartis’), an innovative molecular diagnostics company (Euronext Brussels: BCART), has the honor to invite its shareholders, warrant holders, directors and statutory auditor to its annual shareholders' meeting that will be held on Friday 11 May 2018 at 2:00 p.m. CEST (‘AGM’) at the offices of the Company at Generaal de Wittelaan 11B, 2800 Mechelen, Belgium. The agenda of the AGM includes the proposal for a new board composition based on the appointment of five new independent board members and the re-appointment of three board members whose current mandates will expire at the closing of the AGM. The proposed board composition will allow for a transition towards a board of directors consisting predominantly of independent directors. Subject to the AGM approving the proposed resolutions, the board of directors will be composed as follows as from the closing of the AGM: Five new independent board members: CRBA Management BVBA, represented by Christian Reinaudo (candidate chairman of the board), Ann-Christine Sundell, Harry Glorikian, CLSCO BVBA, represented by Leo Steenbergen, and Luc Gijsens BVBA, represented by Luc Gijsens. Additional information on the proposed new board candidates is included in the explanatory note prepared by the board of directors which can be found on the Company’s website. Four existing board members: Herman Verrelst (CEO) and the re-appointment of three board members, i.e. Peter Piot (independent director), Hilde Windels BVBA, represented by Hilde Windels (non-executive director) and Roald Borré (non-executive director). -
International Congress on Targeting Ebola 28
CONFERENCE REPORT Journal of Virus Eradication 2015; 1: 282–283 International Congress on Targeting Ebola 28–29 May 2015, Pasteur Institute, Paris Sabine Kinloch-de Loës1* and Colin S Brown2,3 1 Division of Infection and Immunity, Royal Free Hospital, London, UK 2 Hospital for Tropical Diseases, University College Hospital London, UK 3 King‘s Sierra Leone Partnership, King‘s Centre for Global Health, King‘s Health Partners and King‘s College London, UK Introduction messages throughout the meeting. Professor Piot, one of the discoverers of the Ebola virus, described a recent return to The International Congress on Targeting Ebola 2015 was held on Yambuku in the DRC, the site of the first EVD outbreak in 1976. 28–29 May 2015 at the Pasteur Institute in Paris (www.targeting- The current state of the healthcare infrastructure did not reflect ebola.com). The meeting was organised in partnership with the the many promises of future investments made at the time of the COPED of the French Academy of Sciences, the French Task Force outbreak, a poignant reminder that we must not assume that Group for Ebola, the Pasteur Institute and the Task Force for current promises of investment will always materialise. Infectious Diseases. Publication of a summary of the meeting by the organisers is anticipated in an open-access journal. This paper Professor Muyembe-Tamfum, a microbiologist with four decades aims to provide a brief overview of the main discussion points of EVD experience, warned how outbreaks have become more during the meeting. frequent since 2012 in the DRC, both with the Zaire ebolavirus (EBOV) strain now seen in West Africa, and the Bundibuyo ebolavirus This meeting brought together more than 300 experts in the field (BDBV). -
Praesens Foundation, Institut Pasteur, Institut Pasteur De Dakar, University of Nebraska Medical Center, Twist Bioscience Consortium Win Prix Galien Medstartup Award
Praesens Foundation, Institut Pasteur, Institut Pasteur de Dakar, University of Nebraska Medical Center, Twist Bioscience Consortium Win Prix Galien MedStartUp Award October 24, 2019 -- Consortium Developed an Integrated Solution for Better Preparedness and Faster Response to Outbreaks and Epidemics in High-Risk Areas -- BRUSSELS & PARIS & SOUTH SAN FRANCISCO, Calif. & OMAHA, Neb.--(BUSINESS WIRE)--Oct. 24, 2019-- The Praesens Foundation, the Institut Pasteur, the Institut Pasteur de Dakar, University of Nebraska Medical Center and Twist Bioscience Corporation (NASDAQ: TWST) today announced that the consortium is the winner of the Prix Galien MedStartUp award in the category: 'Best Collaboration Dedicated to the Developing or Underserved Populations Worldwide'. The consortium works together to develop, quantify and scale up a range of innovative solutions on the continent of Africa to ensure better preparedness and response to infectious disease outbreaks. This includes assays to rapidly identify pathogens developed for and by low and middle income countries that are not necessarily addressed by the traditional diagnostic players and will benefit the communities that need it most. “Past and recent disease outbreaks of Ebola, SARS, MERS-CoV, Zika and Dengue, have shown that infectious diseases continue to affect many lives while also representing social, economic, and national security threats that can quickly evolve into global health crises1, causing major human suffering and imposing enormous economic damage,” said Dr. Rudi Pauwels, -
Meeting Report: 26Th International Conference on Antiviral Research Q
Antiviral Research 100 (2013) 276–285 Contents lists available at ScienceDirect Antiviral Research journal homepage: www.elsevier.com/locate/antiviral Review Meeting report: 26th International Conference on Antiviral Research q R. Anthony Vere Hodge Vere Hodge Antivirals Ltd, Old Denshott, Leigh, Reigate, Surrey, UK article info abstract Article history: The 26th International Conference on Antiviral Research (ICAR) was held in San Francisco, California from Received 2 August 2013 May 11 to 15, 2013. This article summarizes the principal invited lectures at the meeting. The opening Accepted 8 August 2013 symposium on the legacy of the late Antonín Holy´ included presentations on his pioneering work with Available online 21 August 2013 nucleotide analogs, which led to the development of several antiviral drugs including tenofovir. This drug has transformed the treatment of HIV infection and has recently become the first-line therapy for chronic Keywords: hepatitis B. The Gertrude Elion Award lecturer described the anti-HIV activities of the CCR5 inhibitor Human immunodeficiency virus cenicriviroc and the reverse transcriptase inhibitor festinavirÒ, and also reviewed the evaluation of bio- Hepatitis B degradable nanoparticles with adjuvant activity. The William Prusoff Award winner reported on the cre- Hepatitis C Herpesviruses ation of NAOMI, a computer model with 21 enzymes to predict the activity of nucleoside analogs against Antiviral therapy hepatitis C virus (HCV). Other invited lecturers discussed the development of countermeasures against severe dengue and the potential of RNA virus capping and repair enzymes as drug targets. Topics in the clinical symposium included the current status of the anti-HCV compounds sovaprevir, ACH-3102, miravirsen and ALS-2200; the evaluation of single-tablet regimens for HIV infection; and the investiga- tion of cytomegalovirus resistance to CMX001. -
Johnson & Johnson to Acquire Tibotec-Virco
Johnson & Johnson to Acquire Tibotec-Virco NEW BRUNSWICK, N.J., March 22 /PRNewswire-FirstCall/ -- Johnson & Johnson today announced it has signed a definitive agreement to acquire all of the assets of Tibotec-Virco NV, a privately-held biopharmaceutical company focused on developing anti-viral treatments, with several promising compounds in development for the treatment of infectious diseases including HIV. The transaction is valued at approximately $320 million in cash and debt. Johnson & Johnson is expected to incur a one-time charge of approximately $145 million, or $0.05 per share, upon closing, reflecting the write-off of in-process research and development costs. The transaction is anticipated to close in the second quarter of 2002 subject to customary closing conditions and regulatory approvals. Excluding one-time charges, the acquisition is not expected to impact earnings for 2002 or 2003. "Tibotec-Virco will provide a good strategic fit with our current pharmaceutical research and development operations," said Dr. Per Peterson, Chairman, Research & Development for the pharmaceuticals group of Johnson & Johnson. "By combining Tibotec-Virco's expertise with our own research and development activities, we will expand our drug discovery and development capabilities, particularly in the field of anti-viral therapies." Headquartered in Mechelen, Belgium, Tibotec-Virco applies the latest techniques in ultra-high throughput screening, pharmacogenomics, molecular biology and artificial intelligence to discovering and developing new drugs. The company has drug discovery and development programs focusing on potential new drugs that are active against drug-resistant strains of HIV including two products in early clinical development. Tibotec-Virco also has early stage research programs concentrating on the development of treatments for hepatitis C and other infectious diseases. -
Responding to the Ebola Epidemic in West Africa: What Role Does Religion Play? Case Study
WFDD CASE STUDY RESPONDING TO THE EBOLA EPIDEMIC IN WEST AFRICA: WHAT ROLE DOES RELIGION PLAY? By Katherine Marshall THE 2014 EBOLA EPIDEMIC was a human and a medical drama that killed more than 11,000 people and, still more, devastated the communities concerned and set back the development of health systems. Its impact was concentrated on three poor, fragile West African countries, Guinea, Liberia, and Sierra Leone, but the tremors reverberated throughout the world, gen- erating reactions of compassion and fear, spurring mobilization of vast hu- man and financial resources, and inspiring many reflections on the lessons that should be learned by the many actors concerned. Among the actors were many with religious affiliations, who played distinctive roles at various points and across different sectors. This case study is one of a series produced by the Berkley Center for Religion, Peace, and World Affairs at Georgetown University and the World Faiths De- velopment Dialogue (WFDD), an NGO established in the World Bank and based today at Georgetown University. The goal is to generate relevant and demanding teaching materials that highlight ethical, cultural, and religious dimensions of contemporary international development topics. This case study highlights the complex institutional roles of religious actors and posi- tive and less positive aspects of their involvement, and, notably, how poorly prepared international organizations proved in engaging them in a systematic fashion. An earlier case study on Female Genital Cutting (FGC or FGM) focuses on the complex questions of how culture and religious beliefs influ- ence behaviors. This case was prepared under the leadership of Katherine Marshall and Crys- tal Corman. -
Life Sciences 2010.Key
LIFE SCIENCES FLANDERS Prof. Dr. Ann Van Gysel, Managing Director FlandersBio FLANDERS, BELGIUM Centrally Located Biotech hub SUCCESSFUL BIOTECH HUB • World renowned research centers, universities and hospitals • 143 life sciences companies with biotech activities • 118 conduct innovative R&D • Flanders ranks no 2 in Europe • Total market cap, stock listed biotech companies • Flanders Ranks no 1in Europe • Annual life sciences convention >900 participants LIFE SCIENCES AREAS • Medical Biotech - focus on healthcare, from diagnostics to therapeutics • Plant Biotech - largest R&D hub in Europe, from molecular breeding to GMOs • Industrial Biotech - focus on bioprocessing, from enzymes to biofuels and food STRONG IN R&D • Innovative research • Strong life sciences companies network • Big in Biopharma • Clinical excellence INNOVATIVE RESEARCH • High quality universities • Excellent research institutes, focus on life sciences • VIB [world class biotech research] • IMEC [focus on nanotechnology] • CMI [translational medicine] Ind. Products Health care Agro & Food R&D provider Tech provider 143 BIOTECH COMPANIES 12 24 21 15 64 Ind. Products Health care Agro & Food R&D provider 13.000 Tech provider EMPLOYEES IN 384 R&D 1.163212 >30.000 in total 4.648 6.652 BELGIUM, HOME TO ... • Pharmaceutical companies • 5% of the top-100 drugs are developed in Belgium • Per capita the highest number of drugs in development • Total production: 5.2 billion euro • Total export value: 34 billion euro source: pharma.be CLINICAL EXCELLENCE • Dense medical network • -
Resistance Analyses in HIV Infected Patients with a History of Multiple
Sex Transm Inf 2001;77:449–452 449 Sex Transm Infect: first published as 10.1136/sti.77.6.449 on 1 December 2001. Downloaded from Resistance analyses in HIV infected patients with Original a history of multiple antiretroviral treatment article regimens Andreas Plettenberg, Dirk Albrecht, Thore Lorenzen, Volker Paech, Heiko Petersen, Thomas Fenner, Thomas Meyer, Rüdiger Arndt, Kurt Hertogs, Rudi Pauwels, Thomas Weitzel, Albrecht Stoehr Objective: To assess HIV-1 isolate based resistance profiles from extensively pretreated patients and eVects of a resistance guided switch of antiretroviral therapy. Methods: In a prospective study phenotypic and genotypic resistance analyses were performed on HIV infected individuals with failure of the current therapy and history of at least three anti- retroviral regimens. Antiretroviral therapy was changed according to the results. Viral load and CD4 lymphocyte counts were measured at baseline, after 10 (SD 2), and 24 (2) weeks. Results: All patients (n=52) failed their actual regimen. Currently versus ever previously taking the specific drug, resistance associated mutations and phenotypic resistance to AZT and 3TC were found in over 80% of individuals; resistance to DDI and D4T was detected in less than 10% of cases. A resistance guided switch of therapy was followed by a median decrease of viral load of 0.5 log10 units after 24 weeks. Individuals resistant to two or more drugs compared with patients with resistance to less than two drugs of ongoing treatment, were switched to a regimen contain- ing DDI, D4T, and a PI or NNRTI. After 10 (SD 2) weeks viral load decrease was pronounced in patients with resistance to at least two drugs in the previous regimen. -
Cultural Practices and the Transmission of Ebola in Sierra Leone: Lessons Learned from a Medical Anthropology Perspective
University of Northern Iowa UNI ScholarWorks Dissertations and Theses @ UNI Student Work 2019 Cultural practices and the transmission of Ebola in Sierra Leone: Lessons learned from a medical anthropology perspective Abubakarr Jalloh University of Northern Iowa Let us know how access to this document benefits ouy Copyright ©2019 Abubakarr Jalloh Follow this and additional works at: https://scholarworks.uni.edu/etd Part of the Infectious Disease Commons, and the Public Health Commons Recommended Citation Jalloh, Abubakarr, "Cultural practices and the transmission of Ebola in Sierra Leone: Lessons learned from a medical anthropology perspective" (2019). Dissertations and Theses @ UNI. 944. https://scholarworks.uni.edu/etd/944 This Open Access Dissertation is brought to you for free and open access by the Student Work at UNI ScholarWorks. It has been accepted for inclusion in Dissertations and Theses @ UNI by an authorized administrator of UNI ScholarWorks. For more information, please contact [email protected]. Copyright by ABUBAKARR JALLOH 2019 All Rights Reserved CULTURAL PRACTICES AND THE TRANSMISSION OF EBOLA IN SIERRA LEONE: LESSONS LEARNED FROM A MEDICAL ANTHROPOLOGY PERSPECTIVE An Abstract of a Dissertation Submitted in Partial Fulfillment Of the Requirements for the Degree Doctor of Education Approved: ________________________________________ Dr. Christopher Edginton, Committee Chair _________________________________________ Dr. Jennifer Waldron Dean of the Graduate College Abubakarr Jalloh University of Northern Iowa May 2019 ABSTRACT The link between culture and infectious diseases has long been established. This is primarily due to the notion that culture shapes and influences people’s beliefs, actions, and ways of life. Such beliefs and their accompanying actions ultimately contribute to people’s risk of contracting an infectious disease. -
Janssen Diagnostics and Biocartis Announce Launch of Influenza-Respiratory Virus Panel on the Idylla™ Platform
PRESS RELEASE Janssen Diagnostics and Biocartis announce launch of Influenza-Respiratory Virus Panel on the Idylla™ platform Mechelen and Beerse, Belgium, 30 November 2015 - Janssen Diagnostics, part of the Johnson & Johnson family of companies (NYSE: JNJ) and Biocartis (Euronext Brussels: BCART), an innovative molecular diagnostics company, today announced the launch of their first infectious disease test on the Idylla™ platform. The Idylla™ Respiratory IFV-RSV Panel has been developed by Janssen Diagnostics and is intended for the detection of various strains of Influenza Virus (IFV) and Respiratory Syncytial Virus (RSV). The Idylla™ Respiratory IFV-RSV Panel received CE-IVD marking on 18 November 2015 and is being launched for commercial use in Europe and other geographies recognising the CE-mark. Janssen Diagnostics has appointed Biocartis as co-exclusive worldwide distributor of the test. Respiratory viruses are one of the most important causes of morbidity and mortality throughout the world1 with the influenza virus killing at least 50 million and up to 100 million people in the last century alone2. The majority of diagnostic tests currently used for this market are rapid immunoassays which are chosen due to their low cost and convenience. However, one of the key downsides of these rapid tests is their poor sensitivity. Negative samples are typically re-tested in a central lab with a more sensitive molecular test, delaying time-to-result by many hours. The new Idylla™ Respiratory IFV-RSV Panel, running on the Idylla™ platform, combines in one single product the speed of rapid tests with the quality and sensitivity standards of central lab tests.