FOR REFERENCEONLY
.... The finanrid dcniii ofam& mrdc for ruppon ofidentilid iiidividuilt haw h.cn cxdudd. ISBN I 86983s 166
RLgitcrrrdCharity No: 210183 Ptinrd byAhacusPdnringCa.Umiud Governon JulimJrck, BM. PhD sir rmr 0uia
Pmfaror Sir David Wothmll. MD, FRCP, FRS
PmfnrorSir Hans K.mb.5. ScD. HonFRCP. FRS
PmbrRoy Andrmn. FFS
Secremy Bridget M Opiluic. ScD, FIBid. FRCPh C 0 N T E N T I c H A 0 R II A H*S P I E f A C E
Chairman's Pmhcc ...... 5 Dimoir Rrpon ...... 6 Lord Fnnb ...... 9 SirJohn McMichrrl ...... 14 Mmrgrmrnr SmRofthcTmn Finmm ...... 17
Nmrmcimrrr hnd...... 21 Infmion 2nd immunity Rncl...... 24 Molrmiirrnd Oil Pmd ...... 27 Physiology and Phrrmrcology Pancl ...... 31
Clininl Imcrnr Gmup 34 Tmpial Mdirinc inicrnt Gmup ...... 37 Vc,.rinrty lntcrn, Gmup ...... 40 inrcrnrrionrl inierni GNU^ ...... 42
Suppon lorthc HixotyofMidicinc ...... 48 Wcllcomc inrritum for thc Hinoty of Mcdicinr 56 Writomr Cmrm for Mdinl Scimw...... 62
Cnnr Information rcnonri Suppon ...... 66
Uniisrnd Institurn Other Suppon- 153 imrmwionrl Ptagnmmc . Suppon forthr Hiimty ofMdicinc ...... 178
4 c H A I n II A N*S P I E F A c E
Hcnry%,ouldmnrthcTmscm mrkcauhrirniial donation Dl-toh Report for thcbmcfir of mcdial rnnrrh in Amcrio. his hinhpirrc. This prhas hmn domindby the knowldgc thrr grrrt Thc Cownon haw rhcmforcdrridcd 10 mrkc a gnm of changnvouldwronocrurin rheTmSandin thcunivcniria mmc 10 Burroughs 5400 million Ihc Wcllwmc Fund, and mrdial whaolr which rrrciw its funds. ppblc in fiv~qurlannual inrialmcnts commencing this
)?a"
Thnc mQ~chrnga in iheTrurr hwccoindddwith palidol dcvciapmcnrr which will Jmott aminly grrrtly rkourmivitin. Thcanhiishmcnc inMay 1972ofIhc OW= ofSdmccrndTrrhnoiogy undcrthc Chinalbrofrhc Duchyaf~~cmirwillhdm~~i~~~~,i"1993 !hati'
likly to aKsr thc wysciena is fundd and manrgd oatiandiy. Thc -mi of the himry divide in rrnizry duelion with the raring up afrhc Highs Fduorion Funding Countih lor Englrid, Smtiind md Ma.and thc dricrminrrion hy piirtirnr thmughour rhc politial lpmmm
to incrc~~cthenumbrnofrtudcna in univmitinwhih rrducing rhc unit of mmac per student. will hive pmlound rKrro on thcrbiiiryofuniv~nintnfftaundrmkrrwtrrh tha is inrcmalionally mmpnitiv..
7 a I R E c T o R*S n E P o R T LORD fRANKS
Onccrgain. ihcnpid gmwth ofihcTrut1hrrrcquiddrgmr cffon hy thcnrfE Igmtlyappmim thrgoodwiil and
ntrcmcly hard work ofmymlloguo rhmughoui nhcpar Lord Fnnh,who wua Twmc fmm I963 to I982 and roting but ahilmring yo,. Chairman from 1965 m 1962. dicdon I5 (kmbcr 199Za.r BRlUGETMOGiLViE rhc age 0187. Hc war a mn afmormour dirrincrian.and many obiruaries havcdrady hem published. The
apprcciirianthat hut opmdhis personality WI the addmr delivered by RiihardSmcthursr, Pmvorr of Warcctrrr Cdlcgc. Oxford, at rhc Mrmotiai Service an IZUmmbcr i992arthcUnivrnilyChurchafSlMuy rhc Virgin, Oxford, which is rcproduccdhcrc in full with prmiuion.
8 9 LORD FRANKS LORD FRANKS
m me that his quditio WE rhosc ofthc mmplerc school: of mcim hiiroryrrwrii~rafphilo~uphy:ofModrrrw~lluof
Grmr From mcimi hiwry hr pin& hir iikiong inicms in
&grot mmemcnir ofhinory. mdnpccidly thc mwrmmtr ofpmplnou,afCcnrnlArir-in hirluryw hefinirhrd rndingi liwvolumc hirmryofthc Moguls. Bur shin mining
M m marc thin Ilifcrime'r fwinrrion: he had I mind which
could 1- big prtrcrnr ad=Ia(c them m rmdi c~mnwith hmih~rking~rtiruinion,likc thclprn ofr prhuilding.
Om cvrninghc kcpi UI and our invntmcnrzdvisn. fmm Schrodcn, ofwhich he warrhr rimca Dirrcmr,spellbound
IS he m-wotc rhr canvmtionrl hrdtgmund ppcr which all inwrmmf rdvircn hdirvc all dcgc invufmcnt rommiiicu
ncd hcfor. they nnpmpcriy wiw ihc performancc ofthc ponfolio. "WA now," hcuid, kickingour his long legs like m snlorldingAnglrpoilcI.mp.'I don'tthink the'rquirc right."mdfomrd onsomcdirpurd villsgcan the irncCLchanonbordcr. That hcnmc thcccntrrafa vrici of
mnccntiic ring afqumcnt which cnmmprurd lrEum- currmg msrkctv, monctrry plig in rhc UnitedSnrcr. thc UKand Wutcm Eumpc.mdplrntforIhhcaformofrhc
lniiimrimrl Man.tnySyncm. Honqmmpclr mc m
conds however. thzt thcrc may haw h-n family as well as Ginrs influence in this rrchinctuni rkill: 'hc thauid haw
bcm a I~NCIU~cnginccr." one ofOliveis Word fricndr
mld mc. not knowing ihrr this WII indcd thr pmfurion af hir youngrr hmthcr.
Allicd to this IIWC of large patterns, Oliverriro had rhc
skills dcploycd hy ylmcom who tnndziu hrrwcm Iangurgn ofquirc disrent EYIIU~~~~skill. hc gained MmrofihcobiturinofOiiw hivcdnwnztcmrian rothr working for his sprrkling fin! in Mads. He had rhc ability influcnccconhim offfinr..ndrhu~aflhcphiiorophyridcof ID qlir a mmpicx ruk into much smiilcr componcnn, toivc
Grcrit. But hc hadsbrorbcd Ihc ffiniian 'I ought. ihcrcforcl dore pmblcms. and ihrn re.rscmhlrcvrryrhing inm I M' fmm hm family. long hcforc hc mchdOxford. 1. ycms cohcirnt whale.
IO LOlD FRANYS
To condudc I simply dorhc judgcmmr ofLord Bullock with whom I spokon the morning ofhii do&'Hcwurtdy grcrr muofthzrl hrvcnodoubtwhauamr.'
Aulvltier U Chalrman of the Trust This hiicfdscriprion ofhitEontilburionrrChirm.nof the Trustis hadan a mnwrution hc hsd with Dr I' 0
Wiilivni thrr w11mordd in May 1991.
Lord Fnnk fclr char. in relationship ID rhc mmpny, it
UN ibrolurcly senrid thz rhc Trust UN noc involvcd in my renrcwirh the bwinarcxccptas arhucholdcr, which it had a right to bc. To quoa him, " - convrmrion. nlk- Yci - but inwrfmncc. poii5y making, with regad m rhr budnru- No". in his viw, the attitude of chc Gmpmy itrclfwv mlaud by rhc id& ofSir Hcnty Wellcome. in
that itUN in bushes 10 makc a pmtit, cmnidy md
rightly, hut the motiwion UN not sokly msximum pm6t and that this was pdywhy many pcoplr mycd 6: the whole of rhcir menwith Wrllmmc. Concerning rhc business. Lord Fnnb said that nowhys it is more
difficult IO irk a long-rcrm viw 2nd char during hir rime as Chrinnm, thc Trust mok IUI in dvidcnds thm it might haw don. haurn the Foundation ncrdcd the fun& to buiid ;p in -lurch. Lord Fnnk thought there wuld bc rrimcwhcn~hcbwincuw,apmdcdrh~irwouldb.mmr imporrible m miinnin the =hionship that cxirrrdduring his time brwm rhc Tnut md the Fwhrion. Hs rcmcmbed rhc hrcafrhcNuficldFoun~tionul warning of the prcntid dmpofhaving dl rhc Trust's
tggr in onc bubt hut. m him. thcquadon w,wkn the
12 I3 John McMirhicl war horn in 1904 and cducmd at Kirkcudbrighi Academy and Edinburgh Univcrriry, fmm which hequalified in midicinein 1727. Heohraimd his
MD (drh Gold Medal1 in 1733 for a rhcris OD liver fihrorit. Bcrwrcn qualification and 1939 hc worked in various positionsin Scotland and London whcre he aisndcd his knowlcdge info the physiologiol upmr of
the hmr and circulation. This cxprrimcc led to hir
appointment w Reader in Mdisinc at thc Parrgraduarr
Mcdiral School of London Univcrriry in 1939 md 10 his succ4ingSirFnncir Fnicfrrrhr Pmfcrrorin 1946rt :hc agc 0142. For thc ncxr 20 ycan hc Icd the xhool
with enthusiasm IO ih cminsm position.
John McMichd h.cun.3 WdcomcTmrec on rho iciiicmcnr ofSir Hcnry Dale. Bcoux of his cammitmmn, hc mr a vcy busy man md yet I on hirdly rrmcmhcr him
miuinga meeting. It ii obviour rhcicforc rhrr hr placd the acridtics ofthcl'mrurr very high an his list ofprioriris. HI
14 15 NANACEMINT STAFF OF THE TRUST FINANCE
Unit for Pollq Research In Science and Medicine I Jochhn,BSr. PhD. HmdofUmit
Dmii Frronin who hubrcn rhs CbicfAcmunnnr at the
16 17 FINANCE
Supportfor Medid Rwch Dufing the ynr theTmr's apdiiunon mdicrl march
arludingthe hirtory of mdicinc ronlkdB7 million (P5.9million for 1990/911.Thsronl v.lucofrpplimti@x
w11U48.8 million.An rniiysb ii shown in fipn 4.
I8 19 SUPPORT FOR MEDICAL REISARCH NEUROSCIENCES PANEL
tFmm March 1592 ttFmm Augur 19% tttFmm f&uq 1992
21 20 NEUROSCIENCES PAWEL N E U.R 0 I C I E H C I3 S ? A ll E L
uniwniryrnffin wriow wys. faicrzmpls DtAln rhr rwdy ofpnicns uringadvmdMRI imaging in the Thomron (Dlpanmcnt of Physiology. Royal fac Horpini ciiniol sating. School afMt.didnc) mwdcd a Rcsnxh Luve
fellowship. in rhii wy. ~pp,panfora qiwcmmr Imum Thc brndrh of rhe Pan& remit in SUpponing ncumxicnm wupmvidrd mdlow DtThomion m be ruhsnnrirl~ is funh~rillusmrcdby thccooiinucdruppn amrdcdro rcliocd from tnching 2nd adminimriveduriu fora WO- Pmfccrai Michael Geldcr md DI Alzn Stcin (Dlplnmcnraf year period. This will diow hcr m ~.omc~ntniconher Prychimy, Univcniryof Oxford) for ihcirwork m ntablish rcchniolly demanding rtudyaflc phyriology and thc influirnrcofpxcnni psychiatric dimrdcrondiid
marpholou of ringic axan synrpric Canncctioni bcrwem dcvurlopmcnc, Spccilinlly. this axrrrhh daigdto study
nmmna in dcnr ncocotr~x.using intncclluhr arordingr. rhccNect ofr pranrsuffcringfmm tin ntingditordcron a child? dwclcpmenr. Wirh nrli~r~upportfmm rheTtun. Dr Stein had mdidchc dcvclopmcnlafr cohort of infmrr 1r1hcrgcafl2m 14 months. Thiinewpmgnmmcgnnt hamrumd that thr dorelopmcnr ofthir pupof childan
will bc fallowd up JI rhcy mL school 26ai 4'12 m 5'11 yun. Thisgmup will hccomprd wirhothctmhons
whore mathcn hsd suffcrrd fmm I dcpmrivc dirordcr. In
22 lNPECTlON AND 1I)UUNITY PANEL INFECTION AND IUUUNITT r&ne~ INIICTION AND IMMUNITY PANE1
J &U, MA. DM. FRCP U";mipfo&d MOLECULAR AND CELL ?ANEL
The Molmrhr mdGiI Pdmnridcn pmpsb inwlving bvi~rarurhinthchnud.~ofmolrml.r~.nddlbiology
(including bimhrmisry. molrcvlrr Y~IR~of immunology. dnclopmcntrlhiologyind genciicr). iogcthcr with ghr appiiodan of thcw dieiplinn ta uhc study afdiniol. vricrinrryad trapid mcdtinc.
A mnl 14 ncw pmpuh for longcr-term support wtc coluidmd and six n.wzwids wrr mrdr The Rncl m panimlarly pleadto rccommcnd2 Ptinripl Fcllowrhip to Pmf-r Daugi~Farm. which will rnrhic him mdhis group to move fmm thc Johns Hopkins Uniucnity.
Bdtimorc. 10 thcSrhool ofCiinial Mcdicinc. Univmity of Summeruhoolr
Gmbridgc. who. hrwill have thczdnnmgcafrrcns IO ThcTmit conrinucditssupport ofporrdmorai Iahonmry clinid mtdd fog his work on Ihr rcgulrtianormdhody- mnnm Two haviiy avrr-$uhrcribcdmuna wctc affndin mdiaad inllunmrrion. Pmgnmmc gnnir wcrc2w.rd.d 10 ghr BiochrmiuryDivision of chc Uniad Mdioland Dmal ~worminmUKrcirniirtrwho..rllo~~l~ movingra rhr Schools (UMDS) ofGuy's 2nd Sr Thorns's Hospirrlr. Thc Univcnityaffimhridgc. One will suppon Pmfcuor retcr dghih munrin this mia- GmeTqehg 2nd Homolognu. Goodfdlow'r work an the grncrin of mammriirnIOL Rmmhiluiian -wasdimid by Dr Manin Em- DrJohn dcrctminrtion, mdrhcathn a study ofgolrtis imprinting Hnthand Dr Andrew Poncr. by Dr himSunni.
Thrninthmum-DNAklatd McthodsofHummCmcticr: YACCloninginCcnomcAnrlpi.-wudi~d by Dr David kdly, Dr Tony Malum md Dr loannb kgpuuir.
28 MOLECULAR AND CELL PANE,
30 PIIISIOLOCI AND PHARMACOLOGY PANEL
Although thc ptch-drmp rshdquc isan errnardimrily
powcrful tool. it amofgive m inrighi into the pmcurrs inwlvda;, malmlarlFvel.Twoappmacha havcbanuxd
10 pmh mom drcply inm the fundnmcntd changn occurring
31 ion. mylm thc4mcmbnne. Molmlir biologiol rrchniqunnn pmvidc dmihofrhc membnnc-spanning proteins which conidmtc uhr ion rhrnnds and this approach hubanrdopd hyDr Malcolm Hunrrrfmmthc Dcpnmcnt of Physiology. Univcnigof Lcrdr. Dr Hunter holdra WcllwmcTmr PmgnmmcCnnr for hi, mdinof
ion rhmneb in mm1cpirhdid ccllt. Hcir nilw hcing fun& togcrhcrwith PmfurorJohnFindlay fmm dc Ucprnmcnr of Eiochcmbityto study ihc molcccular hiologyafthcachannrlr mbjems such II psychiatry and ophthdmology an lvndd Zhmugh fcilowlhip schemctadmin1rtct.d bythcTnuc't advisory pdt.hut mon mining frllowl in subirclr such as mcllidnctugyorprrhologyrrccoruid.rrd inn compcrition, which in rhc prundcrrcvimw held fom iim ondidncs coming fonwd lor MdiiGduatc Fcliowrhip, and rheGovrmonafrhcTnu wcrcplclxd to be rbk CO ~~CINCthc fun& avriirblr far this whmc ID meet the demands mrdc upon it. Thc Tmsr has long rrgrtdd march mining *I onc ofin most impomnr mivitics. and thctuccctrofthisrchrmr hrbccn noed byrheGovrmom with particularpl-rc. DnpitcrhcrurcatofthcMdidGdwreFcl~w'hip rchrmcrnd rhcorhnrniningrchema lordinidrru. rht mnl numbcr of mdinliy qudiid ma& uoLn "iving their 34 35 TROC~C~LMEDICINE INTEIIEIT CROUP RerwchDmloprnent Awards In Troplul 2nd many 0th- distinguished irieniun with whom hs hu Medlclne workcd dowly during hit arur. B~cauwofihcm~jorcmnomicandradrlpmbicmrhcing munitis in 1. dcvcloping world, many young dinial md nondininl scicniim who iindcnikc mnrch mining in dcv&pdmunrrin. indudingthc UK. fail m rciurn 10 their homcrountryahcr mmplaion oftheir mining pcdd (unully;l PhD marly pasidonon1 tnlning).Torddrnr this problcm in ihcrrn of rmpial mrdirinc. thcTmtr has intmducda nwform ofruppon. Rsnrch Dcveiopmar Awards in Tmpial Mcdicinc. Tbac awards am rimd at dinial or nondinial scicniiiii who ID compkringr rchcmc ofminingai docmnl or juniorporrdoctonl lev4 in thc UK 2nd who have prrmrnrnr positions IO mum ID in their homc rountdn. hipicnu afan award recivc rrsrrah npcnrrr for ihmyanminiriircwork in their hamcinrrirurionr; innch yar individurli am also givrn pcnonal suppan and mrch apnwr for oncvirir ofnp to thrcc months at &e iabnmiy ofthc UK~panror.Tbcrrh.msd~oprovidnoncrcturnair flight prryorlo,lcUK~panvlrrovirir ihcavcruuwohcr. 3.8 I VETERINARY INTEREST CROUP VETERINARY INTEIEST GROUP 40 41 Srherntl of support and rvyh mule durrng 1991192 EumpnTnrrllingRecuchFIUahip There awards arcduigwd m bcilintcvirits ofbnwrtn rhrcc months 2nd WO ycm by porrdocroni (or cquivrlcnd worLtsfmmthcUK(orrh~Ripuhlis~flr.lmd)ro Irbonmriu in minirnd Eumpa and wnvcmly by scicwists in mxinlrnd Eump. (including the Gmmonwnll of indrpcndrnt Stdm lrhonmrln in the UK (01 dcRepublic of lmimd). kxhCouncil institutions and units, while unablc IO apply far pmja 2nd 43 INTERNATIONAL INTEIEST GIOUI INTEINATIONLL INTEREST eROU? On91 mSlpr92 5 1 5 4 3 1 3 I 21 1 - I 2 4 3 2 3 I - 3 - - I 7 2 I - I8 I 17 55 18 76 5 i I 3 2 I 22 44 45 INTEINATIONAL INTEIEST CROUP hcimpmwmmt of thcainingrchemn afruppon undcr thcir nmit md the inrmduaion of nwrypn ofaward. Foilowing ronridmdm ofthc Group's pmpmlr 21 the TmNfif Annual Policy Mating. xhc Govcmorr wrc plrvcd m cndanc smnl funding initiatiw. U docribd bdw. SInior European RdFell-hips Awards mrdc undcr this nwly cinrrd mmpititivc fellowhip rchemcirc intmdcd m~uppanouoimdingyoung hiomdial invoiigrion from rhc Europnn miniand who with 10 ntrbkh indcpindmt march gmup in thc British Islo. Applicants will k qardto haw errhlirhed an ini~maiionalrrpurrdon in thcir hid ofaudy. Raipicnn of this impanant nnu intcmationd award arcnpdm kof Ihcumc highaiihrca,IhrTnr,i'~S.niorRsvrrch Fcllwsin Buic md Ciini-i Riomdial Science. 46 Staff members responsible David EAlkn, MA, PhD. Smtq Anm Fdxudh Gran" oflm 48 49 50 51 SUPPORT FOR THE HISTORY SUPPORT FOR THE HISTOIIV OF ME~ICINE OF HEDICIWC Unlvenly of Glupw DworDrJohmnr Grycr-&.dad, 0ncofih.mijordlv.iopmcnt~thitprrrynrforlhUnii his hrcn its panicipaiion in thcntahiirhmcntofihc Univeniry Srhwl of Hinory. The Diretor of dc Unit is on the PirnningCommiltccwhich will hc dnhingr constimiion for chir. whilr Dr Marycritc Dupmis on dc pdIdRacmh Commirtrcwt up ID coordinate mnah2nd Inching actlviiicc. Thc Unirwill rain irrrdminirtnlircidrnriry whik ruhntn~*llyconoihuringm thr widc ~ngcofhltoriol npcnircivailrblc in Glasgow. The Unit mntinuo IO develop ih pragnmmc in rcrneh mdtnchingfmm thr arty modern period m twcniicrh- rrniury hiordrnrc. This year it ntntrcdr. Wcllmmc RclcJrch Scholrnhipfora PhD 10 he undrnrkcn in thr Mcdiol hruiiy hy Mr Hamla Sturdy on'Thr Scoriirh hoardingout of lunaticr and idiots 1857-1 913: m altcmaiiw 80 inrtitwiond arc'. Mr Siurdy's work nrarly dovcrailswith thr Glasgow Unit's upanding activitiu in the hirrory of psychiatry. 53 52 SUPIDRT FOR THE HISTO~V OF UEDICINE Work on cpidcmiologial chmgc in mufh-cut England md the Nonh Su Basin bctwcrn 1600 md 1800 w11 underraken by DIMIty 0ob.oninIhcIrcondyurafhcr Wellcamc Fellomhip. in mllrbonrion with Or Smith. Or 54 55 WELLCOUE INSTITUTE FOR THE HISTORY OF MEDICINE 56 57 WELLCOWE INSTITUTE POI THE nis'ron~OF WEDICINE will cmbls thr Libnry ID miintain andenhance its position U Iprimary inrcrnational mourcc in the history af mtdicinc lmponrni and inicmring~rquiiirionrduring 1971192 induded. forihc Imnognphic Collmionr, thm wr~rcolourrofr physician. il rurgcon and imuwr by m unknown Delhi prinatrmund 1830. Thuc picrmu WEIC mmmiuiowd by the Anglalndirn advcnturcrColoncl Jrmu Skinner 11778-1841). Thc iimc drprnmcnrrcquired morhrrwrrrrrolour, this iimc ofthc Huntcrian rnrromy rrhaol in Great Windmill Lrrn. London. in 1839. by Roben Blcmmd Schnebbelic ld.1847). The printcd book. depmmcnn wx cnriehcd by rhc PurrhusafihelibnryofthcNItiandInrri~uteoflndwriml Psychology fmm thc Polyrcchnic of Lit London (now the Univcoiry ofhrr London). Thc NllP was a SUEI~SDIbody ID thc Idustrial Paiguc Ruorch Board, ret up by the MRC during World War 1. Among iu innurnrid mcmbcn wcl~ CharluShrringtan.CS MycnmdChr,I~Sperrmm;$c Iuw pua psyrhologha contributing book. from their penonrl libnrin ro the coliwimn. ThcNllP Libnry mnsife ofrbout 2000 wiumcr on psychiatry, psychology, sociology. rnihmplogy md mlrrcd rubiccts. mostly fmm the laic ninaccnth 2nd twrnticth cmmrict, bur including mmc 30orroprr1851 ismr. The Wnrcm Manurrriptr Drprnmcnr purchd the ppcs of Robcn Whyrr (1714-17GG). ProLlor af Mcdicinc IC Edinburgh Univeniry. with the aid ofa Ipdri gnnr hom the Governon. The Dcpmmmt nlm purchued prpcn rdditiond m abring holding.ofThomu Hodgkin (1798-18GG) md hi. family, md iomc papen ofCmrgc Bdlingril(I780-1855), PmfworofMilinry Surgery at Edinburgh Univcnity. Fihmn volumu ofmrnuwripr ppcn, 59 58 WELLCO~EINSTITUTE THE WELLCOME INSTITUTE FOR THE FOR HISTO~YOF ~E~ICIUE H~CTOIY OF ~E~~CIUE hzibwcrr U followt: Philip Wilds 'Surgmn 'rurnd' Physicirn:ThcGtmmd Writing of hiclTurner Il6G7-174t~ws~mimdby DrSrrphon hmfmy, UnivmiryofLncurrr, adDr Bynum;AkihitoSutuWs 'Mind and in Dimin EnlightmmrnrBririrh Medicine' w -mind by Dr Rogcr Smiih, Univcnity of Lncutrr. and DI Lwrcncc md Dr Rcnrrc Hauscis 'Serudiry, Nwnrthcnii md the Lw:Richard yon KnRt Ebing 11840-1902)'hy Or John Fomtu, UniwnityofGmhridge. mdDr Portcr. Twrlw rctntch srudents ax dwlyworking within rhr Unit. ~~~ THE WELLCO~ECENTRE OR THE WELLCO~ECENTRE rom ~E~I~ALSCIENCE SCIENCE Thcmrin lriivityafrhcicirncc bundingrmionrofthcTmst ism pmvide fun& forbimcdid Torch. The Wcllmme C~nrrcrims m help this -& IO Roudrh by cncoungingi porithc nniiude IO biamcdid -&by the public. Ihl quirn a bmad ipprorch involving work with whools. the mdi. politicimr. thc public and with wicnritrrthmrrlvct N Guoa* OBE DLin. FSA, FMA Dimr, SmwMwmm THE WLLLCOHE CENTRE FOR MEDICAL SCIENCE MEDICAL Anorhcr intcicsting joint cnrcrpiprisc with thc British krociaion is the dcvclopmmr ofr tyndicrrd scimce 64 65 STUDENTSHI~SAND SCHOLARCHIPS PERSONAL SUPPORT Studmrhips 2nd Scholmhipr. Fillomhips 79 UnivmityA wr. IOf OlnOnl University of Oxford CIOVC fer Mmhcmatid Blology Mr P D Dale under Dr J A Sharut and Dr P K FUnl Modclling wound conmnciian in dc dcrmit (036300iZPZZ). 67 STUDENTIHIPS AND SCHOLARSHIPS ITYOENTIHIPS AND SCHOLAIIHIPS Bristol Unlverrly of Bristol Dcppnrunmt of Biorhunirtv Mr S C Lovlll undw Dr Hilary Mukhead rtolrinmginming apcrimmrs m invurigrtc the rllorreric rrgvlrtion ofpynnnre kinase (0358W92/21. Brighton Cambridge Bil&ton Polytechnic University dCunbridge Aberdeen D~~Z~IIIICIIIof Phnrmacy Dipmefit of Aantomy University of Aberdeen MrMJThomaronvnderDrG W Hmlon Mr S hker undcr Dr R N Laon I)rp.nmeni ofhlolrmlnr md CIll Biology Mioohirl chin1 invrnionofdrug molmle Funaiod intmxciombwmn conid ourpuamnrmlling Mus Chlre M Wood un&r Pmluror IR both [035729W92IZ). xhc monkey's hrnd mefi~mm). A molmbtmmlFii.dthc gatingof ihc KKpotassium nmpn ,)Wm 1035740l~2Zl. . 69 ITUDENTSHICS AND SCHOLAIISHIPS Liverpaoi University of Liverpool Dqutment of Mdirine MI Eihlbeth A Hooks under Dr M J )aCboclon Geneixpmrionduringpmiirmrion md dilfrrcntidon of pmumr uteiliir ulls fmm norm2 and prhoiogiui mmdc (035776U9ZZl. D~pm-t ofPhumPmlogv.nd"hUOPtb MI Victoria] Green under Proferror 0 K hrk Gcncricpoiymorphimofcporidc hyddvcand is impiicrtionrfor dmgthenpy 1035723rnZI. Leeds University of Leeds DepMment of Pureand Applied Biology MI G N Arkw under DrJD Altringhrm Phpiologid and mlrhmicai pmpcrti~oftnlufarmcd mrmmdiantkclarl mu&. mdrhcdmlopmm of innifonnrtion ruhniquu for UIC in cudiacurisrsugry (035897fZ721Zl. Leicester University of Leicester D~p.rtrnrntof Blochemistry MSSum E Critchlow undo Dr A Muweil Thcmolrml.rbui*of~hc.nion ofquinoionedmg.7 fO3S879iZ92~. 70 71 STUDENTSHIPS AND SCHOLARSHlPS St Bartholomew's Hospital Medical Collage u'ib H- Rc.euch InniNIc MI Vanessa J Hadson under Dr R Corder Pia-mdorhclin pmccuingin mdorheliri ceUt (03582IlzZ72Z). St George's Hospital Medlnl School Manchester Dcp~n-1ofGllulnr Md Malcdw Science Unlvenlty of Manchester Mr Judith E Camrrigh~under Dr A P Johnstone Nawich Cyrokinr-mdid cfim on rhcnprrnion ofnitric oxide Mr 5 Allen under Dr N J Bulkid md adhminn moirruln by human endorhclirl cdh Thr role ofinmcdlular ptcin folding on the parr- ~035858fzZ72IZl. tnnrlriionrl modiliation of ~ccrrrolypmreilu (035853fZ9Z). St Msry's Hospital Medkal School Dcpurmmt ofPhpiol0by sod Biophplrr MI jrner E Phiillpr under Dr C AShuukwonh MrSDHunterundcrDrjG RJaff- MicmBbrillrrzhnormdiris in Marfin ryndmme Thcmionrofteunur toxin in rcmponl hnin rcgions: an (0358Wrn-m dmmphy4ologiol .Ndyafchmnicrpil.pticroci using the ramhind rcmponl conical slice (03584n9ZZl. Depurment ofObsrnicsplld Gynncmlogy MI N A Hey mda DrJ D Aplln Unlvenlty College and Mlddluu School of Hormonal ~ntmlof mucin aprrnion in human Medicine mdomcdum: lcicwnu m cmhryo implmntion Depurmmt ofhatomy and Biology (035854iZ9ZI. MS Arvid VWI under Pmfusorae,y Tickle A nw dl hiaiogiai appmch ID thc analysis ofthr wndof onibgc difilcnrirrian f035801IZ92Zl. 72 73 PreStw, Isncmhke Polytechnic Scbool ofApptldBiology Mrjann Ahkwunder DrR W hardDrJ Sin% The nrud mdchmiimr involvedin mniml ofpmkain ~smimin &e ring daw (035730lZJZ'Z). Mr 5 Springer wdcr Dr A R M Townrend Readinx orpMornt of Bioc%ttry Thc hiorhcmiiiry ofvinl mdgnprclmoiion Unlvenity of Reading M4sr M&e Huumnn under Dr I D Campbell (W5834L?Y92/Zj, DcpPrmvnt ofMiuobmlogy SrmmdnudisofSHlmd SH3dowinr (035747L?Y92/Z). Miss Glllirn R Huahlnlon under PmttmorJW AJmmd and Lbantory of Phpiology Dr D J Ennr MbLauren Fadmore wdet Rofplor G K Mh Mr G A P C Bums wder Dr M P Young Lalation and dunrrcrizarion of the gcnc mmding thc c.iidrr Phorpholipidripriling 2nd NI~DYII in ullulu pmlifrniion bnimioniai and corticwubmnial prrhwyr in the mcpmr for hcprririr A YiNS (035755lZJZ). andgmmh 1035753IZ72IZl. primrtc hnin f035749L?Y92/Z). St Andrew DIpMmrntofEx-nmnl Plychology MIS Surm J France under Dr D R Moore University of St Andm Mr R C de Borchgnve under DrJN P Rawlint SamcdTcctrofariy horinglouon thcfmcrionand Dvtdhysholagy Limbic-striatalininnions in ainmtiond lnrning mnnenions of Bc fcrir rudirarymna (035746/ZJ92!2), Mr bunF Allen derDr P Wlnn (035744/Z72/2). An cuminationof the intcnaiont bmnrhc striimand Mr M Nublr undcr Pmferror C Wakemore the nudw rcgmmtipeduncvloponrinw in the nt Rqulriion of rympsc formacion in thc dcvcloping uibmi f03553IU9Z). mna (035748/7fl2/Z). Shemeid Portsmouth Univenityof Sheflleld Portsmouth Polytechnic Dcwmmc ofMdirioe smd Pharmacology BiophpioLbornrmia Mc A Hall under Proferror I R Peake Mr D Meqhunder Dr G G Knee idmrilicrtian and maiysis of the DNA rqurncm regdating DNA~qumcsremgnirion hy Ed7124 mnhyluc thr livcr-spcci8c rnnrriprion oftk pmtein C md (035732fZ92IZI. pmrcin S gcns (W577llZJXZ). MlsS Michelle Webb undo Dr K Firman Domain ~f~~flli2nd subunit intcnaians of type IC rcliricrionmnhylucl fO3573IlZ92~). 74 75 I STUDENTSHICS AND SCHOLA~SHIPS STUD EN TI HI?^ AND SCHOLARSNIPS Imperid College of Science. Technology and Mr Gaii Waikinrhrw undw PmfessarJHlch Medicine A moleculrr md ccllulrr rnalyrir ofncumtoxin-indud ell Dcpnnmentof BiochcnLtry dntli f035970rn22). Dr Y U under PmfessorJ0 Dolly Countrr-rrringbotulinum ncammxinpoisoning by targcring Nottingham nrurmiidngantibodininto alf.crcd choiincrgicnews via University of Nottingham innomow inngonci forms ofrhc murated toxin Depmaf of life ScLnce fo359.93lmzizl. Mr P 5 Jones vndcr Dr D R Bell Thc ralcoi~hc'pii~mcpmiifmmrmiurrd r.rcplor'in King's College London (KQC) mrcprormdiucdrmlity (035949N9Z). Phm-logy Gmup Mr K McNaughr under Professor P G Jenner Ncumcoiicig of scnhydmiroquinolincd Queen Mary and Wesfleld College Deplnment of Eioehcmistry Miss Kerrtin Kmmer under Dr IR Phiiiipi Dwlopmm of hcpatoq~ccuI1u1. systems aprnting dmg- m.t.blizing wzymn (03595lN92Z). St George's Hospital Medlcd School DcpMmrnt of Gllulv nnd MalmiuSdence Mks Shinah Z Iqbl under Dr C L bshford Lpmionand purifirrtionofwild.rypcand mutated alpha- minofS~$l~lmmrraurrru:nn~lytirufm~mhnncm.mbnncdrmrgc inducd byihrputified toxins f0359471Z92m. 71 77 STUDENTSHllS AND SCHDLARSHIPS Mr IC Dirk under Professor D E Onions Thr anine immunodrfcirncy ryndmme f03553UZ9212). Edinburgh Dundee Univenity of Edinburgh Univwrity of Dundee Deppnmwt ofVitcrillpIJ.Clinid Studies Dcprmncnt of ANtomy md Phyaiolagy Mr G H Stun under Pmfesror H R P Miller Dr Atiron A Eiiion under Probwr M J Rennin immunologiairrrivriionofcuunmu. mast c~lbin rhmp: Thrhrtcmgcndlyofneumd diumchmnclr: m cffuu on ccil tnllic rhmugh rhc drrmir f035589/,?921Z). durmphyriologid rrudy wing moirmiu bioiopid and monsrirution ruhniqucs (036IWZ92E). Leicester Univsnity of Leicester Depuunent oiNcphmlogy Drsj HarporunderDrJ hehrliy Polymeric igA in igA ncphmpxhF sire ofodgin and rmrion 1034937Imlu). 78 79 FELLOWSHICJ fELLOWSHI?I Degrrunentof PvblicHdth .nd PoUcj Dr JuliaE C W Verne under Dr P Elliott lndividurlchmnic apme IO outdwr air polturionin &tion ID rhildhoodwharc: a srudyaftLhwkhddm in Kirklm (03537NZPW. Unlvenly College London Dcpurmrnc of Biocbnnty. nnd Molcollv Biology Univeniy Cdlega and Middlesex School of Mr DTJonuunder PmfwarJanetM Thornton Medicine A fold mogniiianapproach to protein IITUCIU~Cptdicrion DepnrmrentofGmmunity Medidn. and dncmimiion (o36.€Qu9zla. DrY Ln-ShiomoundvProferrMGf'lamn London Lriy-onwPirkinmnirm in lrbrion IO murrcdddn!+ing Institute of Psychiatry wicr in childhood (exredon) ~01942m89f4l. Depst-t ofEpidemidogy and General Pnnice Dr M Prince un&r Profurnor A H Mmn lhc Garpd Oak projrct: dementia, dcprcuian and activity limitation in thc community - awdy of the chmct&tiU ol 11 changingdddy popularion owtime (0353821~21ZJ 80 81 f ELLOWSHIPS Klng'r College Schwl of Medlcine and Dentlrtly DqnrtmrntofMcdicine Dr J P Midi under bfexor A M McGwor 7hemdoainc~dndpuroincmi~~flGF.Iingiummn*oid- inddmde~rrbdumandgmvxh inhibrion (034WZBllV. London Chving Cmu and Wesbninster MediulSchod McdiCJ bit Or E Lyntue MUMunder ProferrorS L Ughmm Conicommid-mdirrcddmRNA W~NUin rhc ni pituitary gbnd. and the passible mlcof iipomnin.r.iad pmicins (cxtrruiod (030820IZ89l&. Imperial College ofscknce, Technolow and Medicine Ikputmcllt of Bioiq(y Dr M E Murdoch undcr Dr R M &Iz& Clinid md immunopihoiogid nudisofonchwml di- in thcrkin. is modifiapilion byiwmminmd dation m onchmml dircrte (addiddirionrl ~-l(o3YNwN1/4~ King's Collage London (KQC) Phydolag. Gmp Mr C Lou- under Dr R W A Unden Thc mk of pcriodonnl ligmmt mwhmor.cepron in the jaw. opcnbg r.flcx in halrh and dwuc (0353173/2ZZ), St Bartholomm's HospitalMedical College Orpsrtmrnt of Medicine Dr AM cntedi wdcr Dr AHWas Replition of the gwmh hormonrindcpcndcntiniulin.liks gmwth hrtor-bindingpmrrin (030821IZ8Pl&. 83 FELLOWSHIPS FELLOWIHICS Dr A M Thornson under Dr W G Wood Globin gene rcgulaionduring clythmid diff.rmti&n (0354lWZl92ZI. a4 FELLOWSHIPS fELLOWSHIP5 Brlghton Universltyofswrex Schwl OfBiologid Sdaccr Dr Nkoh I Bidwell under Dr T S Collnt A rubrysrm in the honqkwhich detmt vebdry dirmntinuiria2nd morion prnliu (~~on/9uzI. Cambridge Univenity of Cambridge Dep~rtmatof Phyiolog. Dr H P C Roblmon un&r Dr T D Lamb Synrpticmnducnncnmd information pro-ingin dmd irvisual comicrl ncumnn ~0364011m21z). DrY Tadmor under Dr DJTdhurrt Coding of mni~tin mmpln imrga (0364031Z921Z). Edinburgh Univenity of Edinburgh ~cputmcntofrhnrm-iogy Lh P C Knox under Messor I M L DomlLon Ths umicofcrrnoculrrmucclcrR.rcnrfcnlbrck in visual pm-ing (03640mza. a6 a7 FELLOWSHIPS London lnrtltute of Neurology I)rpmmcnt ofCl1nir.l Prychology Dr G Barren under Professor E K Wadrp An cvcnt-alamiptmrhl siudyofthc timing and loalindon ofbnin activirywmimd with wrd rririml and compahmrion im health and dimx (0347I6L791~1. Institute of Psychlay D~~P~WAIofrlychly. Miss Kathryn M Manden under Profuror) AGny Giugow Dodopmrnt ofcland hybrid cholinergic cell lins for Unlvenity of Glasgow intention of cognitive kncrion (034i~lL3. Department of Physiology DrDSSlepieundrrDr GLSmirh Royal Free Hospital School of Wclne Edinburgh Thc intnccliulw mwhmirms underlying rhc slow inormpie Depupupnror of Physiology Unlrenfy of Edinburgh rapam 10 t length chmgc in ordirc muelc Dr Margaret E appleyard under Professor K M Spyer aputnmt of Bochmby (035999/7JJZ/Z). Nonduriol aciimml ofauerylcholinutcnrc in rhs rnmrndirn b ] G We mder Dr D K &pi bnin (03547IGBZZ). Thcmnr ofincnulluiwpmtrin tnffic byoh&isadd l034754LWIEl. 88 89 FELLOWSHIPS London Univenlty College London Dcparmmr of Obdsrsod Gymedogy Dr Bemadem Modeil undcr Pmlermr C RDdecL Dmiopmrnt af the science ofmmmunicy gcnnicr Lsbmamry ofrhpiology (0349rnrnZ). Dr P A Smith uder DrJ C Ellov Modulation afoldum ~umntsin prnrintic B uiL 1034539m9lIz). Aberdeen Reading Unlvenlty of Aberdeen Univeniy of Reading tkparmrot ofOphth.lnology tkparmmt of Biochrmiivy nnd Phpiology Miss Fbns H Harper under PmfarmrJ V Fomrmr DIM ESymondrunderDrMALomu An invnri@grrionoftupp~r ell mrchaniim in i maof Thc mlcafihymid hononct and hmwn dipox tirrus in the organ.tpd8c autoimmunity @3H5rnW. mntmi of nconaid thcrmorcgulrtionmd rcrpintion l03445~91IW. Birmingham Unlvenity of Birmingham Cambridge Depnrtmrnt of Physiology University ofcambridga MISSMade Ncyl~nunder DrJnnrcsM Manhdi School ofWinid M&nc The mla ofrhc rmin-angiorcnrin ryltcm md rrrirl PWfMlOr D T FWnUnder Profuror D K kn natriurriicpcptid~ in dmrmining rrd lundon in ZNIC ad Rcgulaion ofmrihody-mdind inflammation chronic hyparir (O~~W~KJ?Z?Z). 10364s91m31zJ. DrElisbefh AMudd under Rdeuor Sir David Wuthrnll Conirol ofmRNA pmcningmdturwcrin E mli 103s8Soimm~. 91 FELLOWSHIPS F E L L 0 w I H', , I King's College London (KQC) Phy*oIogg Gmvp Mlrr Ere M Taylor un&r MnorM W B Bndbuq md PmferrorTJPeten Mmhmbmsofimnmd mnrfminin mnrponraovredd cndothrlium fO3G4~Zl. London lrnprlai College of Science, Technology and Colchester Medicl ne Univerrity of Essex Depurment of Biochemhey Lkpvrmat dfchcmisuy md Biologicd ChcmLey Mr K H KhDo under Pmfwlrr Anne Dell Mr A MrLeLn under Dr PJ Thomlley and Dwrlopmmt sad appliotion of new rtnrcgia for hlgh- Masor P H Sonluen wniitivity FAE-MS mdyxi oforhohydnr~connining The dinial rignitionccofihr moditiaiion afchrglyoulvc hiapolymcn f0364asimziz~. rymm in dirhcra mdlitu f03G454lZ921Z). Institute of Psychtatty ofe+,iw Miss Julia A Nun" vndcr ProfesorJ A Gmy and Dr R G Morris Contrihurian ofihc hippoamput m mrmory functioning invcrtiprcd thmugh mlgnctic mllmn who hrvrundngoncrurgiol trcafmmr farcpilcpry MIS Jane K Relton under Dr Nancy] Rothwell (036451N921Z). Inrcrlrukin-1 mcdkion of ischaemic drmrgc (03G467LWW. 92 93 F e L L o w I n.1 r s Leicester Unlvenlty of Leicester Deptment of Phyriolqy Dr I D Fonyd~eunder Fmfumr P R SmReld Madulation ofrynrptictnnimirrian in thcCNS: qdailaion ofrrlcium 2nd parasium chznndr bypfcrynrpric-pmn (rdditiondcquiprncnrl (031301~9W. Dcpurmat of Pathology DIDC Wniith MdcrPmfeuorH Waidnunn T-cell mlmncc in autoimmunity (additionalequipment) ~ol95oelmzal. 94 fELLOWIHIPI FELLOWSHIPS CardHT Universlty of Wales College of Medicine Cardiff Drpumrat of MddBiodcmimy Or B P Mwgan under hkzarG H Elder The pithvgnic mlc afporc&tming toxintofihc immune ryrirm (mcnrion) (01~~93lZL Edinburgh Univemlty of Edinburgh D~putlnrncofM&nc DPJR Serki under PmferrorCR W Ehnnlt Molrmlsr rnd bblogiol mdk of mnimstcmidrcccpmir nnd rtcmid mcnboliimin the bnin (arcmion1 (Of733~lE). 97 Unlvenlty Collegeand Middlesex School of Medicine LO"&" Dcpsmnrot ofMimb&gy Blrkbeck College London Dr P C Onpbuloh under Dr G A W Rook DcpPrvnrnt of Cherntty Evrlurdan ofihc.Rmof~piimrithenpyuingM.weam Mrl-kr!aLAnlhoyunderDrJKNichhon an adjmct to chcmoihcnpyin the mnrgrmmr ofTB and NMR tpwroxopicirudinon the mcribolic mdbiochemical TBIHIV pcicnts fOX265IZ9W. cllmtr ofmodcl ncphmtoiinrin isoldrcml cells ~035Ro4m2Iz~. Kingston. jsmdcr Unlvenly of the West lndln Tmpid Mrtnbolirm Research Unit Dr E 5 Cooper under Dr T Forrester The irnmunologioibasis for the pmirrcnrr,and clinical cllccti.of Trirl,urilinfcctianin children (035136RmU). London Nottingham King%College London (KQC) St George's Hospital Medical School Unlvenlty of Nottlnghham Phpiologv Gmup Depurmcnt of GUdv and Molrmlsr Science DIpYrmrntof zoology MI IA Romem under DI N JomAbbon Dr G Bed"-Addo under Prdetror E C Godon-Smith Dr P K Gqal under Professor D Wakelin In zimmririry wdioon thr biaod-bnin hatricr The niiunl hiimry ofhypcr-rcacrivcmaiarid rplcnom& - Host. and pnritc, wi.tionrrdacrmin.nnofimmunc fo35R4zmZlz). gcnaicprcdispition, nhr cR't ofprcgnrniy 2nd rigniliclnu rnpnrivcncu m i&tion (cmmioa) fO32641NMIA)). of lymphoeylc clonaliry ' (034593l~7112). OXhd St Mary's Medkd School HospIU Unfverslty ofOxford Dcp~rrmmtoflrnmuoology Drppuunrnt of Pwliauks DrSurhilr G D'Soun under Rabror J R Lamb Or W McGulre under Pmferror E R Moxm and Dr B M hmiiiai turcpribilig mycabrcrcrirlinfmiont: an m Greenwood invnrigrion ofT-ccll mpomo in ATmd children mdthcir The mlc ofMF.binding pmrcini in mdulndngthrrmriry familin (035213IZ9W. of Pkmmdim.&lripmmt infection in African childrcn f035XWZ'W. 98 79 FELLOWIWICS University College and Middlesex School of Medlrlne Depatlmmt of M-biolw Dr P C Onyebuleh mdcr Dr G A W Re& E~lurtionofrhcrffmrafopiim.l thcnpyuring M. ~wmu m adjunct 10 chcmothcnpy in ths mrupmmt ofTB and TBlHlV pirirne (035265iZ9W. 99 LECTURESHlPS AND SENIOR LECTU~EIHI~S London St Mary's HorplW Medical School Depvbnrnt ef Phpiolog md Biophpii Belfast Dr J G R JoReryr Queen's Univenly of Belfut Cclluhrind iod circuit mmhmirms ofncurologid diiclc DcpMmeat of rhyddogy in rodmu (015171/u9uA)). DrSMWadvndrrDrNGMcHik The O~ICof pccmrking in lymphatic vcrwlr Manchester f0355w/mm. Unlverrity of Manchester Department of Biorhcmiar, mdMolccul* Biology DrJK P Sheehm under Profeuor M E Gnnr oxford Mucus dycopmains-an old barricrundrr nounrrck Unlreniy of Oxford [additional npenwt) (016534/2%73/C). Orpartmm* of P+iiuy Dr A L Stein under Pmfaror M G Geidrr Reading Infmsofmothm with ndngdirodcr; rconimilcd study Unlveniy of Reading (atcluian) (017716E!87/R~. Department of Biocbcmiiy md Phpiologp Dr M A Hmron under Pmfaror C H Rodeck Chcmo-pmn mdchemorcflan in thcfcnuuul nmnitc [additional apcmn) ~OI~IIW~~I~). .. Cambridge Liverpool Unlveniy of Cimtiridge Unlvershy of Liverpool Lkplnmurt ofMrdicine Depnrmrcm ofVa&nq Winid Sdmm Dr C M Lockwood Dr M Benne= undo Pmfumr MJ Ualbonand Chsnrtcrivtian af~urornrigcmpracntin human systemic PmfEtror C J Gukcll wruiiiii by makuhr hioiogicll irrhniqum [additional Pathogen& 2nd cpidemioiogyofvinl dimin hmuurnd Abenleen apC",e) (017802/Z!87/A). rnimdt (034479ZPIlZ). Universityof Aberdeen DcpmntmtofMrdidnc Dr M H N Golden under Profeuor R L Himwonh In .i,~gluitihionc,~ynthnirmdflux nm (011124'93/BR). RCSEARCH D~VELOPHENTAWARDS IN TROCICAL UEDICIHL Dcpnnmm ef MddEniomol~gy Dr Dk-Elfin A Elnrlrm derDr R D Ward U5 400 PROJECT GRANTS An epidemiologiolstudy on the WCOD oflcirhmroirrir in IO2 I03 PROJECT GRANTS hpwnrart of Phyrlolagy Dr K D Thornburl lM3l5 Thc mehhmitm ofnitric oxidcmditrd rcLrarion ofthc rmwrh murtlcrphinmrofthc urinrty bladder i03@49lZ92Zl. Bangor. Gwynedd University College of Nnrth Wales Srbml of Biologid Sr*nscl Belfast Dr M J Lehanc €77971 Queen's Unlvenlty of Belfast r.liimphicmrmbnncfunrtion in O~Yflies Deputmcnt ofBiochmLy io3S4l8Irn2El. D~n K nima fa8 279 A mdyofthcaprpsion ofmumpi viruspdprptiduwirh thc objnivc of mingvirvi from an inFIcrious cDNA donc (03454dl~91l. PROJECT CIANTS PR011tCT GRANTS Bodrnin Glynn Research Foundation Llrnlted DrSEHdford f95 840 Glynn ltcwrch 1Ntimtc The dynamihofDNA mrnmunicriiont (ON779lD¶IIw. Dr P Rich f73 088 Pmtonarionmd ligurd.binding chcmirrryofthemulydc inermdirtmofihc bindcar cenm ofryrodmmc roxiduc fO34505lZ91/w. Brlghton Uniuedtyof Sussex Dr M J A Tanner f97394 lnbonmry of Biochrminry Thc st~~tunlmdlunnitionrl mnmquencclofthc Jsnriolu ' .A Dr Vtrglnia M Fain with Dr J iiayand in rcd di anion mlupomer (hnd3) found in MdmmLn DrSJMorley f167ISI 0wiqIm f034708L391k'I. ~ontmlof pmicin rynthmit in mammrlirn reUs by mimgenr andgmwh bcron f03471W91E). PROlEC7 ORANTS PROJECT GRANTS Unlvenltyof Cambridge Dcpvtmmt ofhstomy Dr RJKeynes with DrtM W Cook €12920 Thc adon ofinhihirory ylympmrcinr in dmvrlopmcnrmd rrgrnrntion ofihsvmebnt.tc rcninl nervovlryncm (additional apenwr) (03140mAL Professor B Maahem €114542 lnncmrionofnomalrnd inflameddmni pulp (w4757lzJ7lla. Rofesror K T Khaw with Dr R Scryg w2 175 A mdomivd double blind mnrmlledtrial of25- hydmxpiramin D ruppirmcntrtbn on blood prmur~ 1035337m9Uz. DrE N G Marsh €68 533 An oxidaivc muplingbryme involved in actinorhodin biosynihcrb (034802/V71fZl. 108 I09 GRANTS PROIECT ORANTS Canterbury University of Kent Bioio&d Lbontoy DIM J Cardenwith Dr Anne Roobol UGSGl Nmmfilrmcnr protcini and kinuu fO35101/~92/ZJ 110 111 PROlECT GRANTS PROIECT GIANTS Or RA Qulnlan 110773 Idmtifiotion, purification 2nd rhrnclniuiion of thr lens- tpccific. bndd fiirmcnr pmtrilu i0338421D!711A). Dr M J R Stark 1126523 Molccculrrgmltis chmacriution of I candidarc yurt intermdiatc fihmmt homologueand athcr novd yat dmodviin nrgrt pmtdnr (036234~72Z). Unlvenhy College Dublin DIplMlrnt ofhlogy Dep~runentofZoolagy Dr M Rogers 1174274 Dr R w Bank3 U9 144 Tnnrmiuih!c mcrphrlapathia: chamcriution ofgmn and Funcrional organizationofihcrbducmrdigici quid mdiw protdn~iha inrcnn with the prim pmicin PrP musclrofthccatuamoddformotormnrml f03G22212772Z). i036032LWZL?. I12 IN GRANT. CROIECT GRANTS Dr Sheila Young with Dr Dorothy Child €15 H2 An invsciprion afmughingin psicnswith spinrl injuricr ~03~33zrn~w Deputmcnr ofRerphtory Msdidne Dr W MacNee with Dr K Doddron l89 e80 The mmhmirmsofscbbnormdncurmphllrcq4stnrian during ~mohad ozone inhzlaionand lung inflammation 103474rnIU). I14 PROIECT GRANTS PIOIECT GRANTS Dr D J Miller f88524 Ihr donsofa-derived fm ndidron the oqandln of forr. pmduaionmdcrlcium rrongein mudr (0346~Il~. Dr J C Neil with Dr B J Willen €117747 A molrculrrmrlpis ofhoit mII mcpron for lclinc immunod&icng vim ~a3s91~m9~~1. Univeniy of Strathclyde Dr 5unm M 0 Hourani €6611 Ik-at bflmmunolo~ Sub- ofpurinoccpmrr in smooth mdc Dr W Hamen €16895 (034852iZ91~ lrnmunarupprrrrivcpmpcnicr of filrdrl phorpharylrholine- containingacmrory-rcrmmv products (@~48QllZ7IlZ). I 116 Leicester Univenltyof Leicester Dep.runnt ofBio&t&y DrRACqer w 597 Nov wiiu to the quinopmtcin rroty- hiorynrhairofthc quinone mhnor of a banerid minc oxidax Ikgumtrnt ofMcdisinc (0351791~2E). Dr R INorman with Dr Sum J Clrr €45995 Sodium-lithium municmmtpon 2nd mcmbnnc fluidity in Dr D R Ctilrhley €47 620 awntid and renal hypcnrnrion (0364nm919u. lrolrrionofrDNk rncoding zdmulin, a qtcskclml pmtrin found in cell-matrix junctions (036504/~92/Z), 119 London Birkbeck Cdkge London orprrcmat of Chcmty DrPJPdler fim NMR rtudcrofihc mtnl-hindingritaofremm albumin (nldditiondape-) (032ll9fZW/Al Ikpmmmt of CTtsllognphy DrHden R Pibil 110551 Thcsrmnurcanduwmhlyofvisual pmtrin. (rddiiianrl "pot-) f033WZZ71/4 121 PROlLCT DRANTS Deputmrnc ofPsychuy Rofuror C D Minden LlGO52 Dr A J Holbnd with Dr M J Brammer €27096 Motor pwmmingin dirardm nfthc burl gmglia Clinial 2nd biochcmid (atcm ion) (0186501~88lAl. rdulrr with Down'r syndrome (atmriod (Ol8l45~8UBl. DrR K Rtknt €31 281 Rapon- demcnu to mmodcnndinduccn In rhe Xnaptu GATA-lgenc (03477l~IlZl. 122 PIOIECT ORANTS Tbmmbosi. U- Unit Dr M F Suiiy l29031 Sirununl and funaionrl pmpcnia of ihccril -mar for umkinnuc type piaminogcn raintor (03086@2/89/B). Dcpnnrocnr of Public Health wtd PoUq Proferror M G Marmot with Dr M Bahk and DrAnn ArtwonhwithDrPlCDeUm rt109031 Dr C Hemman €25 902 Thc impact ofrincruppltmmation on morbidiryand gmmh Thc cffccr ofrocirl and working conditionson thc pdirton in Im.il.lor.gationrl-rp infintr in nonh-mt 8Nii and dmiopmcm ofmyoardial infimion. Apopulsion- (03GG0517J92IZJ. bad wwonrml nudy in Curhoslav.kii. (03G228I279Z). National Heart and Lung lnrtitute Depanmmt of CkdkMdkhnc Dr 5 B Minmn with Dr N J Seven NO5 I40 London School of Hygiene and Tmpkal Medicine Thc uitnmtcture of rhr mntnailerpprm~~ of vuculu SirJ Reid i80 WO smooth muxlr (0345W2791lZA Li.blithmmioftrdai~nhipwhoncinmcmotyofDcC E Gordon Smith (O~QG~~~~ZIZJ. Dr C M Dye with Dr 9 J Pubneli . ... 1324222 Thcqidirnidagyofvirrcnl leirhmaniuir in Amuonim Bmil f03G365rn2Z). 124 I PROIECT C~ANTS Royal College of Surgeons of England Dipsrunat of Biophytio Pmfusoor D G Gadun LIE15913 FAIsions in childhood rpilrpsyand in crmbnl ikharmh- from hiahrmicll and nmctunl rhnormalitbto cogniiivc d>rfmdon l035717/Z92Z). Dr D Jardmwiih Dr A G Ramage fl33 oa3 Thc mk of 5.HT in the mntml ofrcflaly induced chapin =pi drive 10 thc hnn I034957/ZWZ). Dcpuulrat of Protein md Molrmtv Biology Pmferror D Chapman with Proferror E A Barnard 135 100 Endocdnc Unit The noblikhmcnrof* mumbiology raorrh group Profuror 5 R Bloom wim Dr 5 G Giibey fie 787 (03709ZD2/Z). Hprhdamic nmmprptidcY and insulin miwalma l~5ll~m2E). 126 127 ?lOJECT GRANTS PROJECT GRANTS Dr A P Jehnrtonewith Dr 5 S Nurrey I34 072 Applintion of nodNlLVyDtie aprluilan wyram to the pmdvctian ofroiuhlc xcambinrnt panionr ofhumrn thymimphin~uprorto rmdyir. intcmiion with thymimphinmd thr immunc yam f035908f7J92/Zl. Drpurmrnt of Child He& Dr M D binwith Roferror T E SQcey NO193 Plrccnial pcrmobiiity with disordcrcd fcml gmwth (aiciuion) f03oS04lZ89/A). 129 PROIECT GRANTS PROJECT GRANTS United Medkai and Dental School of Guy's and St Thomas's Hospital Divtion of Annmmy and GU Biology Dr I Cohen with Dr G P Wilklns U1 475 Pacton ihri gown inienctioni bcmnrcgnmringuonr and mdvcviroqa in rhc iojmdccntnl IICNOUI sprcm (dditiond cquipmcnil fO334Sl/a/91Lll. Dr SInh C Gwhrie with ProferrorA G 5 Lumden f74 878 Cnnirl motor ~CYIO~pathfinding f03546517l92/Z). hCH CTwmwahDr A Wader fR1 964 Professor A G 5 Lumtden E9437 Chmqa in dement mnccntndon in bmndiiiand wbr CdI linage in ths a$ chick embryo hindbnin dmrmind rmooth muscle during the pmlifrnrivc naponrc by domi mdysk using injicrd cciI.mimamms mrrkrn f03557rn9rn. (rdditionll quipmcnd fO32733fZJ9WA). Pmfuror A G 5 Lumrden with Dr C W FiagsdaleJr E133 714 Giiulu mcdunkmr und.~iyingihcdmiopmEnIofburl ganglia circuirlyriudicdin orgrnorypicairur fC73S5~92/Z). Dr IJ Muon fl2S424 Maic.ulrrFloningaffibmblra gmwh hnor reccptonand thcir apwionduring the dcvdoprncnr ofthr ~CNOWryrrnn ofthcmouv , fo34mlml/z). 130 131 P~O~ECTGRAWTS PROIECT ORlNTI PmfurorAnne E Wamer with Dr D Lamon 1163% An adpis ofrpctific ywnmofmnnclin pmzcinr to nplom funuionrl pmpmics ofgrp junnionchmndr (035019f.%9lI/zI. 132 133 CmOlECT ORANTS PROJECT GRANTS Manchester . Unirmity of Manchester institute of Science and Technology Dtplnwnt ofBiackrnicJ and Applied Mol.ctrlnr BiOiOgf Macow, Ruda Dr) E yewith Dr PFG Sims 0237 Dr D C Sigee with Dr A Muwell N7773 V A Engelhdt lnitltute of MoIuVlar Blology Doriopmcnrofr rnn~formatbnsystem forthc human Loc.liution of DNA gym mdothcr DNA.biding pmrh Dr A D Mimbekov with Dr Y P Lfiw $18 176 mrlarirl padre Pbmdimnfaiipnm (additional apcnru) in E mUhy monoclanrl rnribadylimmunogoldlabelling Colirbonrivcwork bcnvcrn Rvuian scintiw lnva1v.d in the lW3833lZ9llb'~. (0353551Z92Z). Ruuiur Human Gcnarnr Pmgnmms and their mlleapu rbmd in the field ofbiologicrl dmhnb and DNA wquencc Unlvevenlty of Manchester Department ofMdd Gsndo andpis (036G53lZWW. Dcpmmrnt ofBiorhcrntvy and Molrmlar Biology Dr A P Reid with Dr T Stmchan and Dr D Donna! $97953 Dr K M Brindle with Dr AhndnMay Fuiton SI24 020 Thc moirmlrr paholagyof mutations in HuPZ and rciricd A rombincdNMR md mulrmlar bioiogiul appmrd 10 gc"u ~0353011m212~. stdying cnrymo iu rdra ~035012/Z9112~. Lkpuvncnc ofMdidMicrobiology Dr Ruth Manhews wnh Roforor J P Burnie .f55 876 Thi (UF ofhumrn mombinant monoclondrnribadict m HSW in the tmtmrnt ofinfdon f03GZ17~212). Newmarket Animal Health Trust Depvtmrot ofClinial smdicr Dlputment offilland Strurmnl Biology Dr K C Buoett LIZ m Dr I J Miidwith Pmfsmr A R Cmrrman UE 480 A dominant ariy.onrcr mind dyrrtoghy in the a (03505W9W. The rolc ofariirory trninorcid rcEcpmn in the dohus pailidur (amrionl fO318491~~C/. 134 135 PROJECT GRANTS Deplrmtror ofExfimenlJ Psychelogy Dr] N P bdins 1115 112 Deprmnorr of Pipidogy md Phrmlogy Dirrociadonoflimhismnrributionr m memory Dr G W Bennen with Dr R W Chrke 127249 103GI59lmZZL In r,;wdnmion ofnluroprptide iTRH) dnx in CNS (ntmtionl i03107m90M1. Dep-ent of Hum= hammy Dr H M Charlwn with DrJanetMBnndon 127736 The hmrrionrl Sigdf8aX~OfkUkqTSin owm impirnntion (034930l~UZJ. Dr H M Charlmn €170 701 Lymphokine md nirtcd grnc aprcuion -id with gnfm afdlogcncis and xcnagcndctiuuewithinthc CNS i035757m7W. DrCE W Hahn with Dr AMS Black €31 476 (irdia-intory funcrion. in 6cintaivc arr unit and npcrimcnd Iahontory. by an inrpimdgu sinmidal forcing function xchniquc (crtcndonl . (017WUW8)... DcpPrtmrnfaf Biochmrisq DrlWCnig 176706 Phyricrl and gcnnid mrppingofhumrnXp11.3.p11,2md rhcidmifiation ofandidarc pmn farcy. dircva -with pniculsrtcl.rcno ID miinitis pigmcnmu RPl i0352351m2~1. Drputnmt ofzOology DrDIPrl~rdwithDrJMBehnkernd DrEAMum 1121 187 Thcmkofcrypliccpiropin immunigm hookworms io3452llmlG'~. 136 I37 PIOIECT ORANTI Nuftidd Lkp~mrnrofS- Or] A Todd urn 234 Mappingand chmcrctiudon ofr 'y~vI diabcra rurccpribilirygcncan mowrchmmolami I wditr hvmologucon hummchmmoromc 2q fO348l9NsfKl. DrAJRrkeruithDrBGCumming $94 193 Rnponsa to hinocuirrdisparity in the visual mncx (Wrm99IZ9ZZl. Dr K I Welsh f7f403 Dr D J Paterron f69 I93 MHGcndcdgcnn invalvd in anrip p-dog and Physiologlal hommrvir during hypeikrlrcmia: implintionr p-ontion by MHCciui II rnolrmln (035327/ZJZZl. for ordimspintorymnrrol (.ddirionrl fund4 fO34925/Z9I/Bl. D~AlironFBRdingwithMr]CSmithmd Mr NJ M Mommen €248 443 Dr] F Stein f73 739 Thcphydolc+I rolnafihturtihnrnd inirmrlrnrl Hinocul~rin.ebiliryindpluischildrrn (035216IZ9ZZl. sphinacr in miomiiion mddchraiion, and p8hophpiologid clunyn aruning in inmntinmcc Dr ANI G Taylor . €20 GO7 Planep Martinsreid, Germany (035330lZ92iZl. Identifiation and chmcrcriudon ofqoplvmisdyntin in Mu-PImck Institute for Psychiatry malppilb (03570W92IZl. Dep~msrdofNsvmphpraumlDgr , .' Pmfeuor G W Krrurrbrrg 225 809 Depmment if Paydrhy Forrhclifcxicnc.. miningp~m~kEumpcm RofesrorM G Gelder with Dr S E G Park fG9 N5 joumalim (0359J9/rn2/Zl. Pdmin rapiponrc IO d-fcnflunminc in dcprcuivc llncu end lnbantoy of Phytiology clinid "Ovriy , (03GZ73iZ9ZZ). PmfeuortBlabmorelD~ACHrll 2245610 Thcmicof'phpiol'h~tonin ihccontml ofaniiagc mmir in t rgr i g (035403IZ92Zl. 138 I39 ~ROIECT PROIECT GIANTS salisbuy Wirbuy General Horpical Warer Rqionnl Cytopmctic Unit Dr Partcia A Jacobs w 527 Thc origin of human IU chmmoromcaneuploidy (030833lZ891A). Southampton Southampton Gensnl Hospital Dcpnmn.otofChildHealth Dr I Karen Temple vim Drhvlcia AJacobr L95778 Unipmnnl diromy in humrnt (034484li79IlZ). 140 Dr N C Prke with Dr Undi A FothergillGiimore s82 5ao Stmnunl and kinnicmdia ofemall phosphoglyrcntc mume wingpmuin mginccringand hiophyrial appmxhn (034427VZ4JI/ZJ Dr D E Peg with Professor A W Robirds W8i 124 Cryapmcmrion of risucI (~3GOOll~2lZ~. Dr Margaret C M Smith U7 551 Thcmlnofrcpwrpmteinrin lclyrisvcnurlysogcny duision in the SnrpamymphigcPHlWi (@3478i/Z/WZI. Sdrllng Unkeniy of Stirllng DiLion ofBiochmLttyrnd GI1 Eiolagy Dr.Pj Bmphy with Dr Frances P Moore S44418 Rrgulicion ofmydin lipid mrrahoh by rmiblc pho,pholyhtion in normal 2nd hypxic oligodcndmym (a3547m9az). I42 143 IR0CRA)lUl GRANTS PlOGillAWME GRANTS Pmgnmmc Cram ...... 145 DrMASuml fl277036 The mtchrnirmr ofgcneric imprinting implications for gnc cxpmsion and dwdopmenr (036481~92/Z). 144 14.5 PROGRAMME GRANTS London Royal Free Hospital School of Medicine Clurlng Cross Sunley Research Centre Dc-rnt of PhpIolqy Drp~mmtofGIIda lmmuoology PmlerrorKMSplerwithDrMPGilbey €932859 Pmferror M Feldmann Lu OW Thc phpiologiol, morphologioland ncumchrmiolhis of ThcmkofTmllrin humrn~uioimmuncdiia~((rddiiion.l Rcgulaiion ofhurmonc-rtimulrrcd phorphnidylrholine hydmlpis f03G4wm2m. Department of Purr urdApplied Biology Royal Veterlnrly College Professor R M Andenon with Dr D A P Bundy, Department of Medicine and Anid Husbandry DrRMMaizeIr.DrM ESelkIrkmd Pmfermor R M bn with Dr J R Lundm 110991 Dr Deborah F Smith LZG4 07s 'The molrculai intcnnimi bcwccn dsmzgcmd riprirofrhc The WdlmmcTNn knritic DimW. and Biobgy of inmtind micmvill~rmcmbnne (dditloml finds) Helminths Unit (additional fundi) (031283Zl92/A). fO3lO24lZ93JA). Institute ofChlld Health United Medld and Dental School of Guy's and hdiologygynndPh#o Unit St Thomas's Hospital Profermr D G Gidhn 11 213 G47 Dcpnmnmt of Chcm1c.l Pathology Fool lni~niin rhildhwd cpikpty and in ccrcbml bchxmia - Proferror F S Walih mwo Fmm hiochrmiol md~i~~tunl abnormdirin to cognitive l'hc ml~oFcd adhaion molcmla in rkrlcirl muck dpFunctbn (03535Zrn3K). bddiriond cxpcnra) iOl838lWBl92lAl. Royal College of Surgeons of England Depucrnent of Biophpip Profesmr D G Gadien wnh DrSR Wdlim, Dr A Conneily, DrF Vargha.Khadem aod FenellaJ Kirkham a9679 Fod Inions in childhood rpibpry and in cmbnl iwhacmir - Fmm biochemical and sim~~nlrhnormrliiicr rourgnitivc dpruunaion (rnS35ZAmL?). 146 147 IROCRAUUE GRANTS Manchester YNlTS AND IUSTITUTEI Unireniyof Manchester Dep-mt of Phyliologid Scirnm Unitr and lmtil~t~ 150 Pderror R M (ire with Dr M C Steward. Dr P D Bmwn, ...... DrACEllbnandDrKRbv U89 428 Elmrdytytc rnlupnn mcehmismr in sccrcrory cpiihciia (035280L392/Z1. OXrOrd un1verSiy of oxford DIpnnmcnt of Biochemistry OrJK Heath U33 445 Ihr molmhr gnctio offlhroblrrtgmwh bctor rrtrpm (03G328Ei93EI. 149 148 UNITS AND INSTITUTES UNITS AND INSTITUTES Dr W M Wttklm saw For Dr C GilW irudy of nonapponunirtic brcrcrirlmd myrobrcrcrirlinfmiont in HIV-infccrdadults in Naimbi: why rhcyoccur. hawm impmv. dirgnorirrnd clinid mrnrgimmr mdways 10 prcvint tkm (033925IAI9ZA). Or W M Wadins 147921 Fortheprriod 1 Onokr i992to30 September 1993 for adminbtnrivrmrtr amrodrtd with rhc WdImmcTwt Research Labantorin in Nimbiand Kilili, Kmyr f0365GilAl9312). Dr W M Watklns a842s Pmfnror D A Warrell with Dr K Manh $11 930 Sdrrirs. clpentn and quipmcnt far thc pcriod 1 October To nnblirh Icompurcrhucd horpini inlomriion and Odd 1992 to 30Scprmbrr 1993 fora mdyofthcdmg dsrr mllicrion system (035127ILV9ZB). phzrmrmkinnicrmd pruirc rniimcc in thcrhmothmpy of hlciprrum mrlrrir (03656@A!931Zj. Proferror D A Warrell with Dr K llrnh and DI W M W&m a28 i37 Dr W M Watklnr tz4 GOi Sdrrics, nprnrn and rquipmcnr utacirtd wid Dr K Salrrin. npcnscs 2nd quipmmr for rhc pcriod I Ocrohcr Manhi inrcgnrcd riudin on 101crc malaria at the Wcllmmr Nairobi. Kenya 1992 to 31 January 1993 fort Intdyofnon.opponuniaic KEMRl Unit in Kilili, Kenyr (0351271~ZZL Wdkome Tmst Resewh laboratories lucrcrid mdmycohaacrial inlcctionr in HiV-infmd Dr W M Watkinnl a7584 individuals in Naimhi. Krnp (03G56SIAl93IZj. Pmfcuor D A Warrell with Dr W M WaMnr and Fortdminhiniionrmii mcidwiih lcWcllmmcTrurun Profeuor A M Breckentidge U8495 R-ah Lboniaria in Nimbiand Kilifi. Kenya Dr W M Watklnr wah Or K Marsh and Runah nprnruandquipmmrlorthcp=iod IOctakr (033927I,ZAj, Proferror D A Warreil fu(I 160 I992 m 30 Slprrmhcr 1993 for DrW M Wddnr'sNdyaf Sllrrin. nprnra 2nd cquipmcm.uaciatd with Dr K Ih,drugphsrmrmkinninmdp.rvircmirnn~inth. Minh'r inrqnrdmdin on yvac mllrrir II tbc Wclkomr chimoihcnpyofhlripmm mllrdr f0365WU93iZl. KEMRlUnit in Kilifi. Kenyr f03S127lUYZ2). 151 Dr N J Mite U0 WO Additional qnipmmr forthc pcriod 1April I992 ro30 OTHER s~rroiti September 1992 lor wdiaon malrtii, mdioidodt, md scmally rnnimirrcd d-a (03396WAl921C). Equipment ...... - I54 Publioriont ...... ".."...... 155 Sympm...... I56 Cambridge Ho Chi Mlnh City. Vletnam Genome Research Ltmlted Choquan Hospital SilngcrCMu. WeUmmsTnut Clinid RtyllEh Unit DrJSdrwn X44 I28 WO Dr NJ Mke E4 695 Forrhc cmhlirhmcnt of a Genom. RPO~insrinrie blrrin. npnmand quipmmr far rhc prririod IOciohcr (0365221ZY2/2). I992 10 30 Srptrmhcr 1993 for riudin on maloria and IOICIC Inmrirl md vinl infmionr ~03667IlAl931Z). DrN J White f60 083 Pmviiion ofliving.c~ommolLtion. aficn md Lbantoriofor thc Wcllromcl'mnrrt Clinical Rnnrch Unir, Gnrrcfor Tmpicrl Dims,Chquan Hoipinl. Ha Chi Minh City f03396Wk7ZI. Liverpool Univenlty of Uverpool Dublin, Republic of Ireland Aberdeen Depuunurt of Ph-wlog, and Theqwdo Mnky CoHege Dublin University of Aberdeen Dr N R Kineringhim with Proferror B K RhDr D I Back D~puuamtofGmctio Deputmmm of MddMicrobiology md Dr 5 A Ward 149715 ProfesorP Humphries G07G5.2 Or P Cash L23 503 The mlcofdnrg mcnbolitm in drugcfficrcymd mxicily FordrsrringrmioflrhonmtyrFIrcinrnwhiwchnolou Dimpiion ofgncaprcslan duringlronirinf~do"by (03573Y/cT7Z). building (037283lZ73ZA Cmuckic B YiNscr 1034755/mIZ). London London Slrmingham my4 Free H~ylbISchool of Medklne R& PostgraduateMedical School University of Birmingham Depimn~ntof Vidgy rkpanmmt of DvticR.di0l.m Depumreni ofphprmsmlogg Dr Jane E G~ndywfh Dr Gillian E Fnncls and DrD NS Kern U a5o (KM Dr ] M Henley wth Dr N M &mer mm DrTCmn U697 A mnrributiontowrrds rhr Clinical Rmrch Building To pmvidc m image sndysis facility f03f21OZ72Z). .Altmtion. in thmdimmrional cdl S~NCIUISD~intncdluhr ~0347211zl7~z~. loalimiim of mrcmmolmlcrruociitd with prnicular Bristol phyiiologial md dimSIUCI (additional equipmm4 Univenlty College London Univenlty of Bristol f031944LT9O/A). Drprnmrntof Ph-logy Depumrrnt of Mcdidnc Pmfuror D A Bmwn mth Froferror D Colquhoun. Dr D Dawbam 5145 054 United Medidand Dental School of Guy%and Professor 5 G CuibGndy and Frprcrrion of neumtmphic pmrrinr f0355GilZ72Z). St Thomu's Hosplnl Prof-r D H Jenkirwn 5L3 538 UDit br Metabolic Medidns Professor G C ViW A suppkmmr farthc building mtifora mdyofmolccculx DIpMnmt of Pathologyand Mlaobhlog. 116670 plumvcology md molmuhr nmmbiologyof rccrpcan md Dr C J Elmwith Dr W D BilliryDh Dr TJHill and 'Thcprthogencriiddiibnir nrphmpithy: hmilid Na'IH' ion chmdr fO34308rZ72lA). Profwor 0 T GJonu 113 545 antipon aaivily 2nd iu dadonship with mdy mal Cellulae immune rupnrn and phrgocjtic raponrs m vim hrmadynmic abnannditicr (035874rnZ). Nmastlc upon Tyne infaition in animal mod& ofdscvc f034530LDlZ). Unlrerslty of Newcastle upon Tyne Dqwtmrnt of Mlcrobiolog, Dr M Kehoe 516079 BaclcrLl drulcwc hcran (034477L391ZI. 155 I54 OTHER SUPPORT One World BroadcastingTNlt w 0 Dublin. RepublicofIreland To~rdsthrma ofthr'Michirl Swrnn Bursaria' in Royal Colkgs of Physicians of Ireland hmadcuting (03S24WZU). Dr B Kwgh DSW rowrrdr thc miti ofr symprium and ahihidan houcd hy Parliatnenhw Oms of Science md Teehndogl zhc Ropl Cailegc of PhyrirLnr of imlznd @?36437m9ziZI. Dr P M Border Fori WatminircrFdiomhip to hc held at rhc Piriirmcntary Olticc ofSdcncrmd Technology (03173@J,Wo/A), Social and Community Planning Research Mnjulk Field 11% WO A narional IUNF~ofrcrurl attitude md lifcsryiu (additiond ap mr a) (03128uA/9o/AI. Aarhus, Denmark Danish Centre for Human Genome Research Pmfeuor Margarem Mikkelren lswD For the I992 Eumpcrn Society for Human Gcncricr Mming in Elsenore fO35314/ZJW. Unlvenlty College and Mlddlddlerx School of Human Genome Organization Medicine The President and Council WlOWLl Cold Sprlng Harbor, USA Department of Hirmpnthology The funding ofihr Europnofficcofrhc Human Gcnomc Cold Spring brbar Labomtow Pmlewr M 5 R HultwM DrSB Lvru 159w Otpintion (031575IZ9MA). Dr Ted I Gmd2icker US249 4mnrdhution mrdrrhc smnd bicnnidmofcano.of lr Amnirihurion ciw.rdrthcapmwrofz GcneThm~ Aswinion of Pmhol+ ofEur, Gnml md Southcm Mmring hcld in ColdSpring Hathob New York. USAhm Africa (APECSA) (036700IZYmL. 22 10 26 SIprcmhcr 1992 (036016ZOZI. 15G 157 INTERNATIONAL PROCIAMIL Eumplnirrlibanioty Collrhoniion Suppon ...... I59 Ccntnl Fcllowhip Eump md Ovmnr ...... I60 Aurcnlirnand NN. Znlrnd Scnior Fcllowhipr 176 Inicrruiianal Projrrt Cnnw NwZtrlmd ...... "...... I77 London Imptrial Collap of Science, Technology and Medicine Depuuncnt of LUDchrlaby Dr R Reynolds Wim Prdessor N Henchhla Paediatric Cimic Unlvenir/ of me,Swiudand f758.G The cffecu afchmnichypcrphrnylrlrnlncmir on myclinogcncrir in nrs: wlncnhilityrnd rcgcniniionof oligobndmqm f030132~89L4)). 1NTEINATlONAL CRO=RANlE INTEINATIONAL ~ROCRAUU~ Unlvershy College London Dcprummt of Amtomy nnd DNclopmadBiology Proferror el Wen Qn (Depmmtof Hirwlow and Embryology,Third MdidMillor/ College, Chongqid undv Pmferror G Bumrmck ThlhcmkofmdoBilial cdL ofumbiliol mdplrand-Is in the rgul&n ofblood flow (utmiod (03248oNw4l, Glasgow Univenltyof Glasgow Dcpmmmt of Zoology Or Valentinr K Todomn (inrtititutaof Fanriwlogl. Soft) under Or M W Kennedy Smnd pratcin- of Tidin& >pi&md chcimmunc mponrr to rhcm f03G674iZ”/2). London NationalInstitute for Medical Research London De-cnt ofvirology United Medl4 and Dental School ofGuy’sand Or julh Serkediiwr (brtiwte of Micmblology, Sda) under St Thomas’s Hospital DrAJHay Dcpn~latofMcdicinc Babnhm Thrmti-influmnaaion ofr plam polyphcnoliccamplcx or W Peng (Tongji MedicalUnivwriy, Wuhrn) under (034itJZ/usml. DrJPTWardandDrlRCunemn Agriculture and Fwd Research Council Institute Thrmah.ni~mofr~donofiigwmn~n~,md~fitrcnha~~ of hid Phyltoloay Md Genaticr Research D~p~mmtof ’ University College London wlaiiviry for thc pulmonarycirculation f035689LVZQ. Cdl Biology Dqwtmeat of Physiology DrM Kudwelr (Research and Diagnqrticrl Hirtccl~unirL!~ tabonwy, Kwnlov) Roferrw M W Smlh Or R N phiiipwa (Imutute of Cell Bidonand Morphology. C+ under Ac~lluhr.n.lysb ofmcEidid inhicmin nmnadpigrmrll Sofa)under Or M I Whimker tmtsfins fO349Irn9lrn. Forth< +tion ofmiratinlndr bypho,phphoniliionduringlhc orlycmbryonicall~lnin thrrcludin f036309~ZL INTERNATIONAL PROGRAMME INTERNATIONAL riocaAnn~ Nottingham Unlvenlty of Nottingham D~putmmtofZcoiosy Kuopio DrJHemnek (iwicuie of Fam'tology, Cmeh hdq Unlvenity Centnl Hmpltd of Kuoplo of Liencsr. Csrke Budjovice) under Pmfrrror D Wakeiin Depnnmcnr dWinidNnuophyriolosy immunnmadui~tionin pniiiic infmrinn fO3460!7lZ9l/Z). DrKJBrwkr (Division ofBlluhemlmy.UMDS. Sr Thomas's Hospital, London) under DrR A buppinen oxford Thc miiorroufeofaicium miry inroreabni tissueduring Natural Environment Research Council Institute ischamis:8"'P and "F NMRirudy (0356351ZJZ). of Vlrology and EnvironmenaiMlvoblology Dr M hbudr (instilured Wroloa, Slovak Aedemyd London Sciwrr. hdrlava) derDr htrkia A Numli Unlted Medical and Dental School olGuy'r and Thc IOIC ofrick-batnc cnrcpluiitir vim (nimiion) St Thomu's Horpltd Edinburgh (032!755I~lA). Unit for Mctpbolis Mddoc Medical Research Council Human Genetlo Unit Or P H Groop (Depnmenf of Medicine. Helrinkl Or J P Jmemr (hbntond Gcnstlrr. Taleme) under univeniytenmi Horpml) wdcr PrdesiwG C Vibert) DrR CAllshire Microrlbuminuria. insulin rnimncc and sodium-lithium lioirrion afgrncr involvcd in Ebmmoramc tnnrmtriin in muntennnipon vtivily in inruiin.drpmdenr diakric Schimm&mmpponk (035l2~!7ZE). prdrnll: lccffm ~f~"~~~~"~i".~""~~i"g cnrymc inhibition (rxrmrion) fO3l6041U9WAJ. Unlvenity College and Middlesex School of Medicine Depvtment af Pscdinaic. Dr lm E Jarvela (National Public Heahh Institute, Hcirlnki) under Pmferror R M Gadiner Ccnnis linlvgc analysis of htcinhnrik ecoid iipohucinaris Uan.ky-Bidrchow&y dirw. CLNZ) f0358~5'ZE). 163 Puh sbubourg London Pasteur Institute LGMEKNRS U11114 INSERM London Sthool of Hniene and Tropical Medldne CIUhGmda Unit Dcprmnmt 0fGenrti.a Dcpnrtlnmt ofMcdid Pamitolow DFF Milh (Dcpmmenrof Medid Genrtl~.Unlvenlry of Dr Amanda G Rrher (Impcrhl Cancer Research Fund or Sylke Muller (Bernanf.Norht lndtum kr Tmprpl G!qow) unda Dr P Bruler Tumour Immunologl Unh London) der Medicine. Unkrslq of Hamburg) under Gcnc mpmion in H0,W.l-I- null mumimice Dr Diane Mathb md Dr C Benokt Pmferror A H hlrhmb (03GG87f~92IZj. rnrnrhymic dcction afhummT~ccllrcpolm rtudia Cloning. rlqucnringmd mpmion ofglutrrhioncducuw wing Inavci organ ~Itulc.yrrrm (mrcniion) from Onrhomm ~Ivulura poanrld nrgn for nriod-bucd Unit ofEpidrmiology of OnmgdcVinucr ~o33z.92lz9lM~. drugdaign (035aW9m). Dr R M R Bomford under Rofeuar G Biaudin de The HTLV-I immvnogcnicirymd pxhogcnkity National Institute for Medical Research (0352lIlz9m). DIputncnt ofVi Edinburgh Dr C Schmsder (Indtute d Virology. Humboldt Unit6 daLppim Medical Research Covncll Human Genetlcs Unit Univeniy, Berlin) under Dr AJHay Drlinc MlcDoupll(Hunterhn Deml Rerearch Unh Dr A khedl (GemCIncer Research Centre. Institute of Thc~rtu~lcmdfuncrionofthcinflu.nnAvi~lMZ landon Haphrl Medial Cdles) under Cell and Tumour Btologl. Heidelberg) under Dr N D Hude prodn (mcmsian) (0334051Z9l/AA Dr Isabelle Saint Gimns Thccmiion ofpreieirLmu~rian,inrh.Wilmfrumourgnr Ccnnic inrniig.riantwirhin rhe order Spimrharnlil wT/ (03680@7792"~. (almsion) (033257ID9IfA). HeId eI berg European Molecular Biology Wontory Dr Itsbelle Vernor (Wellcome TrurJCrnrrr Research Campaign Inrtltuteo! Unm and DevelopmentalBlologl, Cambridge)under Dr E bnenti A moimlrrrnd funniond rhrnocrivtianof kinain-iikc proteins in Xrnapw ndydmeiopmcnt (036362IZ92fZ). INTIIINATIONAL PROGRA~~E University College London m Dcpmtmmmofhatomy and DmlopmenrPl Biology Dv INap (Dcpment of Anatomy. Uciveniy Medical Leicester Cardiff Scbd of Debrecan) under Pmfesar C J WwN Univenlty of Wcester Univenity of Wales College of Cudiff Synrpricciminyinrhcrpinrlcvd (nrtcnriod Dcplwtrlunr of ccnctkr Depmenr of Pbpialogy f032833P3WAJ. Pmfersoar Y Milner (Tha Hebrew Unlveniy. Jewdern) DrM PirJlb (Scuola Nomle Supertore dl F%a) U& under DrEOm Proferrorv CNndii Muiicdycur PKCsmd rhcir London London National institute for Medical Rerearch Medical Research CwncilMammalian labontory ofDewlopmrnd Biology Development Unit Proferror S W Appihum (Hebrew Unlvenity of Dr M Zucconi (Depu~enrof Animal Biolop, University Jewrallm)underDrJRTarr d RvIO under Or Marilyn Monk Hormonrl rrgdrtion ofaptdonofcrdponc rrrrpmr Methylztion ofX-IinkdgcncCpCrrqurnusmd X- YWk during mcnmarphosis of Dmophih (036G331D92ZJ, inactintionduring mowembryonic dmlopmmr Univmityof York (035239rnW. Drpinmrnt of Biology UniversityCollege London Dr A Vehvszky (Bahton UmndogicalResearch Inramre) Depvunrnt of Medidnc . under Dr C J H Eliion Dr A W Abo (Sackler hwky of Medicine, Tel Avlv Phasmamlogialdmvrtion of mil fdlng behaviour Univenly) under Professor A W %gal l034~87P371lZ). 7hcm~hmirmofmionofp2inciandrhoCD1 inthe &vation ofchc NADPH oxidrw ofphignryric cdlr lo34587lD91la. Aberdnn Rowett Rerearch Inrtltute Division of Biochemid Sdrnra Dr M 5 Se& (Punjab Agricuitunl Univeniy. Ludhiam) UndaDrJPriCe Vitamin E,, tnrupn md mnrboliim in mttk 10366WZJ921Z). 166 I lNTElNATlOUAL PROGRAUME lelden Centre for Blophamaceutlcd Science OxfDrd Phnnnncwtical Tcrhnology UnivmitydOdwd Dr Barbara Nairbea (Deprment of Bblo@l Sciences. Inrtirure ofMolsrul.rMcdicinc Univerriy of Kceie) under DrJohanna A buwrtn Dr R K B Schuum (Univeniy Medid Cenue. Leiden) Thc poicnrirl of kctins as adjuvants in ani microsphcrr under Dr Kay E Dei- vldnc ddivqwncmr ~03G45~92IZl. hloimalzr rnrdin of spinal muscular atrophy (035155IrnW. Amrtmhrn Netherlands Cancer Institute Mr M C Taylor (Depament of Medial Panrimlogl. London %hod of Hygiene and Tropical Medicine) under Pdessor P Barst Antigenic widonin Afriinn trypnocomn London lO3V4017~1Aj. Klng'r College London (KQC) ll~titutefor Clinical Mioobiology Phnrm-logy Gmq DrS M Andenon (DepamentdMedidne Universiy of Dr P M Llboyrie(Depement of Neurology. Academic New& upon Tyne) under DrW VmEden Holplml. Leidm) under Proferror P G Jenner 7%~mlcof~HSPGO-rpcciBcTlymphocylD in nredjumnt Th~.ff~rafdrvgtrnrm.nimdnc~mtoxicinsulton rhe anhritit (034995~1lZJ. rurvivllmd function ofdopminc crll tnnrplrnrr (03G821GY92!2)). I69 INTERNATIONAL PROCRA~NE INTERNATIONAL ?IOCLAM~E Glasgow UnlrerrftyofGlasgow Depnnrnrnt afVndny. Patholqy Pmfesror E Sinski (Univeniy of Warnw) under PmfarorJLDuncmand DrMJSrcar Ccncricconiml ofrebrrnce to grtrointetinal ncmirode in 6hrm (03575lm72lZl. London Guy's HospitalMedical School PurincR-ch Lbonrory Birmingham Dr K#p~ymhbiannomb4rlemb (School of Medirlne. University ofBlnnlngham Lindlyr) underDr H Anne Simmondr Dcpwmcnrafhsrorny Thrmolmubr mmhrnirmrafdmr)3dcnarinsioridy in thc Dr N D Belpev (Nomsbink institute of Bioorganic Y~Cofinimduciion of nodmtivinl drup-&narinr Chemiry. Ruulan Acrdemy of Sciences) under arulogm into rhmothcnpy (0352G8IZl72R). DF B M Turner Chromoromc surhrcpmicinrand nuclrarmv&p; fnucmbly in rn.mmrrin Ccllr f0347bYrZ91121. Harrow London Clink4 ResearchCentre Klng's College London (KQC) Division of Immmoh Biochrmisry Smhn Dr D IGabrilovlrh (Cenurl lnrdrvm for Epidemiology. Or G bga(Depmnr of Cell and Molwkr Wow, Noscow) under Dr Stella C Knight Unireniyof Medkineand Pbrmaq. Uuj.Napocr) under Rnmvirwcrind drndriticcclk f03GG27lZOX). DrJA Wrjgglawmh Uuicand mrdiol reachon lipomme (a3443%a9112]. canterbury Universityof Kent Biologlcrl Lbornmry Dr VV Kurhnlmv (urdioloff Rerearch Centre. Russian Aedemy of SEknc~,Mor-) under Dr M F Tub The urcofm homoiogoluccll.fm mnrlrtion rytrcm m pmbc uhr mlc ofa novel tnnrladon hcror impnrnr for fidrliy of pmrein syntheis in yp.'~ (034744Irnlrn. 170 171 Natlonrl Heat and Lung Institute St George's Hospital Medkrl School lkputmolt of MiacMedidme Lkpnnmcnt of Cellular PodMderular Scicnrc DrA V Vomcnikov (Natioml Cwdido~haarch Centre. Dr Tarian K Rorronrm (Institute of Cytology. Rurrirn London Russian Academy of Medical Scknter. Mmcav) under Academy of Scienter. St Petenburg) under United Medlcal and Dental School of Guy's and Dr 5 B Marnon Pmferior C A Pastem& StThomas's Hospital Thrcffm ofphorphurylrtion on caldsman function 'kpmpcnics aiflow ihmugh nimwrpcnurn Shcningw School of PhridoBy (03568i/Z92/Z). (03649EJZ2Z). DPM Rorlc (Institute of Phybi-. Medlcal ficukf, Univerrlty Zvemvlr Markdc', Kmguimc) under Dr M B Segrl urd Pmleirw H Dmon Thc rok ofhitnminc in lrchrrmirad t.ptrfiuion injury in thr hnm (0346941iWI/Z). Universly College London DcpMmcnt ofhstomymd DcvclopmmtnlBiology Dr A U Z@nrhin (Depanment of Plumnmlogl. Kann Medid Institute) under Profeuor G Burnrmck Royal Free Hospipl School of Medicine A rtudyofnovd coampound..r purinocepcoragoniruand Dcputment dEiochemimy md Chcmbtry rnrrgnninr (0352l21Z9ZJZ). Dr 5 A Kmlenko (Irutiruce ofcytolow, Runirn Academy of Science% St Pelerrbug) under Pmfeuor J A Lucy Oxford Thcmahmirm airmniblcwuolrtian in rkdrtrl mwcie Natural Envlmnment Research Council lndtute lib- (035339ImZJZ). of Virology and Envlronmental Microbiology Or Tamn 5 Giwn(Institute of Pollomyelitisand Vim Royal PostgmduateMedlcal School EncephrlitldeSMwrrow) under Dr E A Gdd D~pnnmmiofMdidne DNdopmcnr ofchimrcricinfmiousdono imm tick-borne Dr W Usov (Inrtirute of Cardiology.Tcmk Research hvivirucs (03502J/~l/~. Cmtre. Rwrirn Aademy of Medlcal Wencer) under OF] M B Hugha md Dr A M Peterr Oxford Polytechnic lhcrnahrnism ainnrirophil-.uodtr.dlung injury in School of Biological and Mdrculsr Sdrncc human lung 2nd in an animal modcl. studied with Dr N IKiytkin (Shemykin Institute of Bioorganic ndionudids mdcxicmd imaging hygrmmr amm Chemistry. Rurrian Academy ofSricnrer, MOSCOW)undu (035199Z92lZJ Pmferror D J Beadle and Dr U& A King Exprnrion aincumioiini imm blackwidow spider venom using baculouinrrnp-on'rysam (036039LV9W. 173 INTERNATIONAL PROCRA~~E INTERNATIONAL rno~namnc Cambridge Unlversity of Cmmbrldge Dcprmnint ofhammy Md Erprritnmdp.ychology Dr hvlcla M Robledo under Dr Bj Everin Ncumbchwiounlsubrrnte of mrdand motivation f037124/A!92E). Rlluninz tz Cambridge La JoikCllifornls University of Cambridge Scrlpp Ruearch institute hpputmcat ofGa&o Dcppnment of Nnuophmpmlog Or 5 L Mxhiuunder Pmkrror P N Gwdfs)lw, Dr htrichM Roble& under Or Chdy L Ehlen Thc irolarian afre&drrrmining pa$wly gena Ncumhchrviounliubrrnta of mard and marintion (036517/N9W. fO37124fWZ?). Rmmlng m Stanford. Connectlcut Sanford Uniwrslty School of Wlcina DcpuuMntof Gcnetisl Dr 5 L Mamiu under Pmfuror H F Wllhrd The iiolaionofrarb.drtminingpithwry gem (03G517/BBZ?). 174 175 University College London Dcp.NII..t of Phumsmlogy Dr G T Smonunder Pmlesnv S G CullGndy Auckland Nan.NMDA giunmric rqonin the ccrrbdivm Unlversity of Auckland fO3652lfAI7Z). Auckland, UrnZehd Depurnm of Gllulnr and M0ld.r Biok Rdurnin~tz University of Auckland Dr 1 Kktler with Dr P bnrldron ff54997 San Diego, Whia Dlpuunmt dMolrrul~rMedicine Mcmbnnc chmndr and lcnr anma (0367i7IZ'XZ). The Wk institute Dr G W Klfurnren under Pmfernv J D Wanon Molorullr Neumbilogy Lbntorg The biology ofbm 7 htrp) inrepins in thc distinct blood. Dunedin Dr G 5 Smntcn undrr Pmbr5 T Heheminn bawdand mum1immuncrytrcmr (035471fZ93IZ). University of OLIp Medical S+hool Nan-NhfDA glutrmric rrcrpron in uhc rcr.bcllum Lpirncncnl Onl Biology Unit fO3G521fWZ). Professor M G Shepherd*im Or B C Monk 1126286 Anmrilungai n%aritrin the Gd;&lrlbinntpium Manchester mcmbnnc H'-A'II'w fO367WrnZI. University of Manchester Dcpunncnt of GI1 urd Srmaunl Biology Dr R 8 White under Profeuor M W J Fergur~and Dr P T Sharp Thcfcmi hipoihrbmir-pituir.r~i~:a nm mdci Melbourne. Victoria f036519L27721~. Royal Melbourne HqW The Wdm and Elin Hdl IN~~N~cof Medid bearch Dr P P W Sherd *im Dr Marilyn M J Dwon €E2350 Dr f J bote under Dr D Kemp Motor unit dwclopmcnt and form in mrU and irg Host rcslwnccfsctonin mdariz fO354~lvu9JI. niammrlin mwda fO3678rnXZI. 176 SUP?OlT Ion TNE HISTOIV OF NEDlClNE SUPPORT FOI THE MISTORY OF UEOICINE Rsruch hvcFell ...... I83 Cambridge Vniveolty of Cambridge Tnvci Grants ...... Wdcllm~eUnit €or the Himy ofMedidnc Couns 2nd OthnSuman ...... 190 DrVigInir Hobdry under Dr A R Cvnnlnghm Forrh.MPhii~ourwinrhrhi~oryofmdicinc lO3~rn2U. I79 SUPPORT FOR THE HISTORY SUPPORT FOR THE HlStOll OF WEOlClNC OF NEOICINE MrM PThomonunkrDrPJWeindiing Mmchhester hlmiddclricnry in Btiuin. L 1913-194G Mditianal University of Manchester opmwt) m4Ml/rnl/A). WeUmmr Unit lor the Hismy of Mcdi&c Dr J V Pirlume Th~mrnufiiturrafbodicr:shcmrdialwoddofthc Indunrid RNolution fum~17m~i). Bmmley Brornky College of Technology +mmt ofLifcScim- Dr N C Rvrrdl Colchester Srylcin wicnrilic mnrrh: a mmtu undintrndingrrrriivity University of Erlu in hiomdidwientc(ndditionni cxpscs) 103291Gl~lB). Deparmcnt of Hbmly Dr Miry N Wetriing unkr Profuror LJlordanan Colchester Mdicins ind13% a wmpmtivc rppmarhm inhntiddc. Unlvenity of Euex 1730-1830 (03494/usml. Unlvvllty College London Dcpmment ofHitoy Wellmmelnrdmtr fortbr Hirtoy ofMcdLine pmfaror LJlordancm Dublin, Republic dlreimd Dr G Lsunkr Or L ICmnd Thcpowcraflifc mnlinl wnccpiions in Fmn~and Bdmin Royal College of Surgeons of Ireland A cridcri editionwith introduction md English rnndationof 1780-1820 f034S!Wl~9l/~. Depnnmmt of Hbtoy of Md&s ihn alDjmrri iid&uwjr f03519~~)uzI. Dr L M Gary under ProlerrorJ B Lyons London A hiriary ofihr Irish pmr lzw mdidrnrirc (036U74PBW. St Battholomew's Hospital Medical College Drprnmcnr of Child H4th PmfarorJ A Waibr.Smith Conqirofdirnhoddim in infinryandarly childhood in #hcoumiieihcmetyinrhc UniidKingdom f037193/ZJ2/ZI. 180 I81 SUPPOIT FOI THE HISTORI SUPPOI? FOR THE HISTORY Of HEDICIHE Of MEDICINE Abewtwyth Unlrenly of Wales Onvr for the Adnnamrnt ofWelsh adGlcic Smdie Pmfusaor R G GWdd I30 106 W&h mdialliimturc of mddirvrl Waln 1036129/2/92/21. London Cambridge Blrkbeck College London Unlvenly of Cambridge LkpuuamtafHiswy Wellmme Unit for the Hirtoy of Medicine Dr M C W Hunter fZS1 DrRKFmxh fZGZS0 Arrudyoflhrmmporirianofm.dio1 mdothcrwridngrby Amdyofthc Ani& lo3G24sla92lz~. Roben Boyls (1627-191) lo348Gola9IIzI. HhyofP+dom adSocLI Svunom Cambridge Dr R Srhdeld wilh Dr P Weir LGS 97G Unlvenly of Cambridge The wimdlrngh oflili 10355mZ9Zl~. Wdlmme Unhbr rhe HirwryofMedlclna &I00914 Slivi~vldapolurofthcUnirfor199U93 lWS67~3ZJ Glasgow Unlrenly of Glugmu Welicome Vnlr fw the Hlrmry of Mediclne f132878 Salariu and apcm of rhc Unit far 1992173 tiupow 103SGnGY9~. Unlvurly of Glasgow Webmc Unit for the Hlmy ofM.dicins Welicms Unitfar the Historyof Medlcim S9S9 Dr MaperireW Dupewilh Addirisndr-xh CXQ~U~for the Unit for 1B1172 DrMAnmCmwher I44208 , 1034197lZ9ZB). Thcorigim. duaiion mdamtsofSmtnbh mdial gnduna; a mnpmtivc mllmixhiognphyofn cohonr London 1871 rod 1911 103GS79Z922J Univenly College London Wrllcome Unit far the Hirmq of Mdd~ I74 321 Salirici and apcnwr ofrhc Unit for i77U73 103s67.%m9m. Lodtbn. Nomich Nomkh Dr K Jones €700 University of East Anglla A history ofdrrp iludin mmr rhmpy in Whimphmii Dcpwnent ofbaomicnnd SochlSNdies (037042IZ9ZZl. Dr S Cherty f23# Horpicai mnrriburory schema and thc Financingofdunory Cambridge London mdpubiichorpidrinrhcpmvinmr.ls8O-l948 University of Cambridge London Holpital Medlcal Cdlege ([email protected]/2l. DrJHenderson 1878 Dcpurmcltt of Epidunioiog illld MddSutLtio Sphiiis priicnrs in iiitrcshcmury Romc (034865NI1z) Dr L Andenen 1lWO Perch Thc inrmdunion ofchimpnciic rcchhniquu in &e UK Mr] 5 G Blair U50 19330-19GI ~0353411ZP212). Thc pmfcriiod hirrory afthe RAMC in rhr ouentkh (03GQ8lZ9ZZl. Halesowen, West Midlands Mclbums. Australia Pmfuror G AJ AyMe *ith Dr May English 11300 Univ-lty of Moniuh Hospital infcaion: ihc middleagm IO the twentieth rcnrury Dcpvtlnat of Phpiology (036618L392IZJ Pmbmr R V Shon U224 John Hunrcir &id aprrimcnrr on dergmwth in der (035368/ZQZ). Newcutls upon Tyne University of Newcastle upon Tyne D~p~mnentafMvlrdidnc Dr FJW Millet f500 ThcwotkofHEArm~rmng. 187~19121ndds~olurionol haithorcin NovrrrdcupnTync. 1711-1948 p3672uusUw SUPPORT FOR THE HISTORY OF MEDICINE Kele Paris, Fnnce University of Keck Hospitai for Sick Children Dcput-t of Gloiw PdIlen Acch¶ltlLult Albuquerque, USA Dr H 5 Tmenr f7ow Dr Ilma L6v.y now University dNew Mexico Thcmndinrcmaiionrl mnringafthr BritiihSocicpforthc Towids chc mst ofnsympium on innovation in mcdirin.: Dcpnnmmt afHttoy Himryofkknce. held in Toronto in Jaiy 1992 hiiioricrl and laciologicrl asp'pccu (035575L3921ZJ. Dr] WSpldle 4 low io3mlmllZ~, An inv-grtion ofGrmrn mdBtirkh mdioljoumb in Phlladelphla, USA connccrion with hit study on Gmnrn rmpioi mdioi Leicester College of Physicism of Philadelphia r-ah and pncricc (0362181~~1, University of Leicester IW~N~Clor the Hlsmry ofhidcine Dcputmcnt dMdr Murrtion Dr Caroline Hannrmy LI856 Beek, The Netherlands MI A E Bmwn I3m A canfcancc on dir-c and macicry in thc dcvcloping world: Dr T Van Hsivoon €4W Towards the cot ora mnfcanccon zhc oblitcniionofnhc exploring noy pcnpcoim ~03504lIZl92Z1. Astudyofrhc hirtoiyofcrnarvirus-txh Nov World, I4724972 fO357WZ9Zl. f03681~2IZl. Southampton University of Southmpton Beillng. China MdidRncpIEb Council Envimnmnrml PrDfetrorXL"0 now Epidemiology Unit A visit to Gmbridge, England immnnmionwish rhcrrudyd Dr C Waqn *ith Pmferror LudmibJ Jordano~ dlm the hiiroryand druia ofrndidond Chine mdirins Arymporiumon Ihcuwofthcqbrt.rric~ndinhnrw.ifia fo367omm r'pccordrfor hiirorid rc.nrrh fO36557/mZLQ. Berkeley, USA University College London Unlverslty of Cdifwnia, Berkeley DcpYmmt ofAnammy and Dnclopmmml Biology Pnrc mdGnRict SNdies D~WFB~num*ithSirChriltopherBa.th.DrS Lock Dr I A Baal fIwD adDr Till M Tmy 44900 A visit m Dublin, London and Chrtrworrh in mnnccrion with A thm-day~yrummcrsrhaalanihchitiory ofhaemoglobin rcmrrhon rhch~nphyofV.i~ntin.Grrrtnkct (0557WZ92iZJ (1628-1W) (035149IZ9W. 186 187 SY~PORTFOR THE nisronv OF MfOICINE Edinburgh Leipzig, kmuny Manchester Univurlty of Edinburgh Kul Sudhon Institute Univenity of Manchester Dlp-cnt of Emnomic and Socinl Hitay DrJLinrur rith DrTG-r €!mil Wellcame Unit Tor Ihc HLtory olMddne Dr L M Gary film A vidr IO :he Wclkomc institutelor rhc Hiscary afhldicine, Dr D J Cantor NWO A visit tu Sattk, USA, incannmian with his mnich om London for periods oftniningrnd hihliognphid A visit to T- and Wumsin in mmmionwith -h on Irish mdidhirmry fO36226!Z92Z), bmiliwiution f036147iZ92/.?), rhc history of ihcumrmidarthritis in Bdain fO34887iZYl/Zl. Ertangen. Germany Neumchlmrglrche Kllnlk der UnivenltVt Edangen-NUrnberg Dr M Buchkldsr am A vidt IO Ihr BritishLihnry mdthc Wcllmmc lnrtiiurc for Friern Hospital thr History of Mdicinc Lihnry in mnnmion with eriy TAPS, RtrpIFh Unit Biirilwork on mnioxomy f036457IZOZW. Dr D R Tomlinron $479 A visit to the &public oflwlrnd fora mmprimon hclwrcn Moscow, Rush Florence, Italy Englirhrndlrirhpvrursrofvylumr (1870-1730) People's Friendship University Dr Luda Ghilli $850 (03S315iZ92Z). Deprtmemt of Hbtory of Mcdidnc R-xh on Lwin mdGmk mmucripaon bomnicnnd Dr Tarlana 5 hmldna LlWO uiraladc mdidnc (03609ZZ92E). Lustlelgh. Newton Abbot To visit rhc UKin mnn.ciion wilh a study of thc main Mr A C Gould LlWD aiintik-r.h on the hiiroryofmcdidnc A vbir the USA in aonnmian with -xh into cpidcmic ~0353lI/ZYZZl. poliomyclitis fO3554@ZYW. Norwich MaasMcht, The Netherlands Unlvenity of East Anglia University oflimburg School ofM&m Lwgqzsand Em- Hiry ~rpurm-1 orrfiFioiw Dr J Bimpprrr fim Mr T Pieterr LlWD Thcdmlopmcnr ofihcrcionceofhlacd rnrufwion in Rush A viiii 10 thc USA in mnnmion with march on the history (0365iWZ7W. ofinterferon (037194iZ922. 188 SUP~ORTFOI THE HISTORV OF MEDICINE INDEXES Cokhwr Kipword index 192 University of Essex hdar ofUnivEnily EurblirhmendRPprch inrriwrn UD Dcputmutt of Sociology Index of Pcnond Nama...... W RohwP Thompson 19470 Lpnw. ofr cwryin on1 hiiiory rrrhniqun for historianr to k hdd at thr Univc~it).ofHcx in 1992193 (0359mrn2Iz). LO"&" London Hospital Medlul College Ikpvtmort of Epidnnioiogy and Medid Statisti- Mr G W7kw-z 19472 Mcdial history for mdidswdcne - a audy afchanga in childbirth 103GC47IZ9ZZ). 191 174 I 123 192 193 194 195 197 I98 199 203 la6 205 207 rn 208 211 213 214 59 211 217 218 219 ' 220 Ennr. 5 W 76 Emin. B I I"-%I45 174 Ew~WmdyRI62l.S Eym.f.linnA 84 Burrhc1l.B 27-28 224 HIILAVS 97 Hiii.~~im HillTJ I54 Hill. W G 88. IO2 Him;wnh.RL IM H~-.J r 13 Hhmo.S I67 Hirct. hl C W H&d~y.Virgini. 179 Hdyon.DR 73 HhnSA 111 HollmmnDV 90 Holdm. D W 127 Holdm.Dp hdyhl 142 Holbd.AJ I21 ~dii~.cr140 H~~..JR Ian HolmrrMlgrnC 81 Holma.PH 102 HmkElivbnhA 71 Hmp.NM 117 Hoplin.lM I48 HopkhAP 143 HopYm.1 155 Horn. G 88 HmalA 133 HmonJD IN Krll,DB IW HaruuhA 165 Kdly. D 24 HOU+.. r I 13 KdQ D R 75 Hounni. Suunni M 0 117 Krlb.FI 141 I1aM.A 75 How. C R 88 HaU.AC lb Hownh.ShciL 15 Ha. A I a0 HowlLP 133 HIO.FR 142 Hm.lli. R E 24-26 37. 39.41 Hubmk.1 Is9 Hndkk.Dlp 106 HuCaAD 127 HuCalhlB 172 Hu+Q 140 Huhm.M.4 103 Humc.R 101 Hum+rb.MI 71.134 Hunrhri-.P 23. 112. 14s. 154 Huni.CI 49 Hun~Dhl122 HW.SP 173 Hunm.JAA I14 Hunm.M 32,118 Hunm,M CW 182 Hunm.SD 72 HumsW N I55 Hud.Hiluy 117 Wlvtr m Hurky.Magro 21 Hurrhinm.CillimnR 75 Hur&ma.CI 70 227. hlhl 79 Wd.J PT 131, 165 Ww.L I87 WNw.HD 121 WdRD IO2 Wrkb.KI 139 W>hJD169 Wad, S A IS& 151 WmQii,Ci 161 , Wh.N-iJ 181 Wd.SM 101 Wsrling.MyN I80 wdIw.p Y Wudmp,CAJ 111 W=,JD I14 WhPH118 Wu1n.A I31 Wamn.AH 73 W$UunsPO 13-14 Wdow, C E 143 Wexrwi&J 68 W&hRG142 W=m.r,AmcE 132 Wad.MuicE 75 WdII. hlh 83 WimU.DA lS0-15J Wq.U 117 WdIunrSR I46 Wmn. G 8 42 mhmm,SB 82 WhTJ31 Wamn.J 161 W.HV I64 Wb".R as97 Wm%nm. E K 89 \VhPrr.sirffinnh 11 %n.NH 115 WYIIJAH Q W+,DN IQ %n.r m Warm.JmnilmA 130 \"wpm,R IU Wib0n.R 125 Wairmmn.8 30 WhinLn. M J 1.R. 163 %n.RA 143 Watkint. W M 110-151 rYhb,E 88 %mRC I81 Wamn,U.inrD 77.llS whirr. NJ 37, ISl452 Wdm",VG 136 WZWD.JD 176 Wm.RAH 71.94 Wdmn.DC 141 w-sr 79 W~l.r,Ebbc&G181 Wm, N 151 WVlLP 75 w*,u,ch,il.=m 81 WilnliJA I16 Warn. F Z 94 Wolds, RC 89, I32 Ww.A 1661 Wdpn. L 62 NI wo-u,suunJ IIU WdGrM68 Wmd.Kdn~J 85 WdWC 84 W&, H R 27-28 I12 WdRI 181 WdLCJ 166 WwbMM 143 WmllN.DM 108