DOCSLIB.ORG

Pathology of Oral Cavity

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Pathology of Oral Cavity Developmental disorders Facial cleft – disorder in the migration of neural crest cells failure of the fusion process and failure of inwards growth of the mesoderm genetics play a part in the development of facial clefts Lateral cleft –the commonest -cheiloschisis (harelip) -incomplete cleft–coloboma labii -cleft extending to the nose cavity - labium leporinum -cleft palate, soft palate - uranoschisis, jaw - gnatoschisis and uvula- staphyloschisis Medial, transverse,oblique cleft, Developmental disorders Vestibular defect Accesory mouth Macrostomy Microstomy Aglossia Microglossia Macroglossia Ankyloglossia Lingua plicata (scrotal tongue) Mikrognatia, progenia, prognatia Fordyce´s spots Dermoid cyst Heterotopic gastric and intestinal mucoses Heterotopic nerve tissue White nevus(white sponge n, AD inheritance intracellular edema Necrosis Mechanical Chemical (arsenic, acid, lye, drugs – aspirin) Scurvy (Scorbut) Hemoblastosis Infections Allergy (ATB, metals) Autoimmunity (Wegener granulomatosis, Lupus erytematodes….) Atrophy atrophy of mucosa and processus alveolares old age diabetes disorders of inervation, Plummer –Vinson‘s sy (atrophic glossitis + epithelial dysplasia in pernitious anemia anemia Pigmentation of the oral cavity melanin: physiological in darked races Hormonal: Graphite spots in Addison‘s disease melanin spots in Peutz-Jeghers syndrome Reactive: pigmentation in lichen planus actinic keratosis Therapy associated: Oral contraceptives Antimalarials Phenothiazines Methyldopa Pigmentation of the oral cavity hemosiderin after trauma rarely in hemochromatosis exogenic pigmentation – chronic poisoning by heavy metals-- lead, mercury,zinc, amalgam Addison´s disease Inflammation of the oral cavity stomatitis – the whole oral cavity cheilitis- lip, glossitis- tongue gingivitis- gingiva Non-specific inflammation Inflammation with exsudate predominance: serous catharral purulent Inflammation with alteration predominance (tissue damage) pseudomembranous ulcerative gangrenous Serous inflammation – stomatitis acuta simplex Inflammatory erythema The mildest form May be local or accompany systemic diseases All known causative agents Transient, without consequences Catharral inflammation Catharrals – serous exsudate + mucus overproduction Etiology: similar as in serous i. Purulent inflammation – stomatitis purulenta Mosty odontogenic etiology flegmonous inflammation may spread to sublingual, submandibular, parapharyngeal areas - angina Ludovici (Ludwig´s angina= angina maligna=morbus strangularis) -cheilitis phlegmonosa – orinates from furuncle, serious complication – spread through vessels to cranial cavity with brain sinuses tromboflebitis splavů, leptomeningitis glossitis abscedens- foreign body actinomycosis- anaerobic mikrobes actinomyces- abscending and granulomatous reacton with scarring Periodontal inflammation and osteomyelitis. - Ludwig´s angina Actinomycosis Pseudomembranous inflammation Pseudomembrane : necrotic tissue infiltrated by fibrin and PMN Causes: -bacterial (diptheria, scarlet fever) scarlet fever– beta hemolytic streptococcus group A, rapsberry tongue , lymphadenopathy, (peritonsil abscessus, otitis, meningitis…) -viral: inf. mononucleosis, influenza - immunosuppression -chemicals- acid, lye burns, Ulcerative inflammation 1. Preceding vesiculous diseases 2. Without preceding vesiculous diseases a. Infectious a. Infectious – herpetic stomatitis (herpes virus 1,2) – tbc – Herpes zoster ( varicella-zoster) – syphilis – Herpangina, Hand-foot-mouth disease – cytomegalovirus (Coxsackie A,B) b. Non-infectious b. Non-infectious – trauma – Pemphigus vulgaris – chemical burning – Pemphigoid – apthous stomatitis – Dermatitis herpetiformis – systemic diseases(SLE) – drug reactions – malignant tumors Vesiculous inflammation Characterised by blisters formation (vesicula, bulla with rapid maceration and ulceration Mechanisms 1. Spongiosis 2. Cytolysis and baloon degeneration 3. Akantolysis = dissolution of intercellular adhesions 4. Epidermolysis (separation of the epidermis in the basement membrane) Viral vesiculous inflammations a. Herpes simplex 1,2 Infection of immunized organisms Infection of non-immunized organisms – (recurrent) Primary gingivostomatitis HSV persist in nerve ganglias, in -childhood, adulthood Fever, systemic symptoms activation arises herpes labialis- resembling flu (lip, gingiva) – painful lesiosn Mucosal edema, erythema, small ulcers healed within 7 days - Dif. dg: Necrotising ulcerative periodontitis Pemphigus vulgaris Erythema multiforme Erozive lichen planus Dentists 2-10 days after contact – herpetic panaritium(HSV1), may last even 2 month sometime axillary lymphadenitids Herpetic stomatitis Herpes zoster Virus varicela zoster Elderly people Immunosuppression, often in lymphomas ( Hodgkin´s and T lymphomas), leukemias Efflorescence spread from one or more ganglia along nerves of an affected segment and infect the corresponding dermatome (an area of skin supplied by one spinal nerve) How the virus remains latent in the body, and subsequently re-activates is not understood. Strong painful rash Often n. trigeminus+ n facialis (paresis) Postherpetic neuralgia Herpangina Small kids Summer time Sudden onset Diffuse pharyngitis Apthous inflammations Apthous stomatitis /recurrent Typical features: aphta/- very common, 10-25% of population. - Minor apthous ulceration - Duration -10 days Etiology unknown - Regular intervals (cyclic) - Free period usually 3 weeks - genetic - Healed without scar - infection - Immunopathologic state (T lymphocytes) - Major apthous ulceration - 1-2 ulcers - Hormonal disturbances - Size 10mm - Hematologic diseases - Duration – may be month - Stress - Non- cyclic - Healed with scars - Some food (citrus, cherry) - More commom genital - Folate and B12 def. involvement - Abnormal response to trauma - GIT disease Apthous inflammations Minor apthous ulceration. Major apthous ulceration Autoimmune vesiculous diseases Pemphigus vulgaris It is an autoimmune disease caused by antibodies directed against both desmoglein 1 and desmoglein 3 resulting in the loss of cohesion between keratinocytes in the epidermis, classified as a type II hypersensitivity reaction. It is characterized by extensive flaccid blisters and mucocutaneous erosions. Potentially fatal 50% of cases begins in mouth Paraneoplastic pemphigus (usually fatal) Pemphigoid Autoimmune disease with subepithelial bullae – epidermolysis Female preponderance Elderly people Pemhigus vulgaris Necrotizing and gangrenous inflammation Noma Noma is a rapidly progressive, polymicrobial, opportunistic infection that occurs during periods of compromised immune function.Fusobacterium necrophorumand Prevotella intermedia are thought to be key players in the process and interact with one or more other bacterial organisms (such as Borrelia vincentii , Staphylococcus aureus and nonhemolytic Streptococcus The reported predisposing factors: Malnutrition or dehydration Poor oral hygiene Poor sanitation Unsafe drinking water Recent illness Malignancy An immunodeficiency disorders, including AIDS Necrotizing and gangrenous inflammation Acute ulcerative gingivitis Vincent´s angina (Vincent´s organisms Borrelia vincentii and Fusiformis) Interdental papillae Healthy individuals Immunocompromised Mycotic infections Candidiasis /disease of the diseased/ Less frequently: aspergillosis, forms: pseudomembranous Deep mycosis atrophic (blastomycosis, hypertpphic cryptomycosis) – Causes: opportunistic inf. - -immature immune system tissue necrosis -ATB therapy -HIV (because of vessels -diabetes occlusion) -anaemias -immunosuppression - Chronic inflammation chronic gingivitis - insufficient oral hygiene, tartar, diabetes, avitaminosis, May be comined with resorption of alveolar processes chronic hyperplastic gingivitis - in pregnant, antiepileptic drugs Granuloma fissuratum Stomatitis nicotinica (palate, mucosal hyperplasia sliznice with hyperkeratosis) Atrophic glossitis (Hunter‘s) - pernitious anaemis Anguli infectiosi (stomatitis angularis, angulae cheilitis) salivary maceration, Fe, vitamin B deficiencies, malabsorption Chronic inflammation granulomatous cheilitis cheilitis granulomatosa - unknown etiology, macrocheilia, perivascular granullomas Melkersson-Rosenthal‘s syndrome (paresis of facial nerve+ lingua plicata) Specific inflammation Syphilis TBC – rare, as complication of pulmonary TBC Acquired syphilis -Treponema pallidum 1. stage: chancre (tongue, lips) Healed spontaneously within 3 month Acquired syphilis 2. stage: condylomata lata Flat placques or ulcerations Acquired syphilis 3. stage: (30% of patients) gumma (very often as intersticial glossitis) Congenital syphilis – Hutchinson´s teeth (peg shaped) Imperfect formation of enamel Hutchinsonova trias: + labyrintitis Keratitis Others: Gothic palate, saddle nose Progressive changes Macroglosia Gingival hyperplasia Leukoplakia Granullomas Epulis Epulides Epulis (Galén) Epulis is a soft tissue swelling of the gingival margins Hyperplastic inflammatory lesions arising from periodontal tissues Epulis granulomatosa Epulis fibromatosa Epulis gravidarum Epulis gigantocelularis (giant cell) Epulis fibromatoza Giant cell epulis Giant cell epulis Progressive changes of the tongue Makroglossia congenital (lymphangioma, Down´s syndrom) acquired (acromegaly, AL amyloidosis) Lingua villosa nigra Elongation of filliforme papillae+propagation of chromogenic bacterias, bad hygiene, smoking, drugs, Fuligo lingue Granulomatous disease Foreign body granuloma Pyogenic granuloma (teleangiectaticum) – dark red, (5mm), similar to capillary hemangioma + neutrophils Oro-facial granulomatosi (swollen lip) Crohn´s disease Sarcoidosis Melkersson-Rosenthal‘s syndroms Wegener´s granulomatosis Histiocytoses Central giant cell granuloma local reactive intraosseal neoplasia, dif.dg – osteoklastoma Pyogenic granuloma Precanceroses Leukoplakia - white patch acanthosis, hypekeratosis zvláštním typem je chronická hyperplastická kandidioza Hairy leukoplakia - tongue margins, in HIV Plummer-Vinson‘s syndrome- atrophic glossitis+ dysplasia erythroplasia- bright red patches with dysplasia .
Load more

Recommended publications
  • Prevalence of Oral Lesions in Complete Denture Wearers- an Original Research
    IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) e-ISSN: 2279-0853, p-ISSN: 2279-0861.Volume 20, Issue 1 Ser.3 (January. 2021), PP 29-33 www.iosrjournals.org Prevalence of oral lesions in complete denture wearers- An original research Prenika Sharma1*, Reecha Gupta2 1- MDS, Oral medicine and radiology 2- Professor and HOD Department of Prosthodontics, Indira Gandhi Govt. Dental College, Jammu (J&K) Abstract: Background: Complete denture patients are often associated with the various denture-related oral mucosallesions. The purpose of this study is to evaluate the prevalence ofdenture-related oral mucosal lesions in complete denture patients. Materials and Methods: The study was consisted of 225 patientshaving various denture-induced oral mucosal lesions from theoutpatient department of the department out of the 395 completedenture patients examined. Data related to gender, age, length ofdenture use, hygiene care were obtained. All the data were tabulated and analyzed. Results: In 225 complete denture patients. Denture stomatitis (60.23%) was the most commonlesion present, followed by Epulis fissuratum and angularcheilitis. The denture-induced oral mucosal lesions werefound more common in age >40 years (59.78%) and in female(52.70%) complete denture wearer patients. Conclusion: The present studies showed that oral lesions associated with wearing denture are prevalent and create health problems that impact the quality of life of dental patients. Key Words: Complete denture, denture stomatitis, Epulis fissuratum, oralmucosal lesions. --------------------------------------------------------------------------------------------------------------------------------------- Date of Submission: 26-12-2020 Date of Acceptance: 07-01-2021 --------------------------------------------------------------------------------------------------------------------------------------- I. Introduction Edentulism may be the last sequel of periodontal diseases and dental caries. In case of older adults, edentulism is essential as a correlate of self-esteem and quality of life.
    [Show full text]
  • Cracked Tooth Syndrome, an Update
    International Journal of Applied Dental Sciences 2021; 7(2): 314-317 ISSN Print: 2394-7489 ISSN Online: 2394-7497 IJADS 2021; 7(2): 314-317 Cracked tooth syndrome, an update © 2021 IJADS www.oraljournal.com Received: 19-02-2021 Dariela Isabel Gonzalez-Guajardo, Guadalupe Magdalena Ramirez- Accepted: 21-03-2021 Herrera, Alejandro Mas-Enriquez, Guadalupe Rosalia Capetillo- Dariela Isabel Gonzalez-Guajardo Hernandez, Leticia Tiburcio-Morteo, Claudio Cabral-Romero, Rene Master in Sciences Student, Hernandez-Delgadillo and Juan Manuel Solis-Soto Universidad Autonoma de Nuevo Leon, Facultad de Odontologia, Monterrey, Nuevo Leon, CP 64460, DOI: https://doi.org/10.22271/oral.2021.v7.i2e.1226 Mexico Guadalupe Magdalena Ramirez- Abstract Herrera Introduction: Cracked tooth syndrome is defined as an incomplete fracture initiated from the crown and Professor, Universidad Autonoma de extending cervically, and sometimes gingivally, and is usually directed mesiodistally. Objective: To Nuevo Leon, Facultad de analyze the literature about cracked tooth syndrome, its etiology, prevalence, pulp involvement and Odontologia, Monterrey, Nuevo Leon, CP 64460, Mexico treatment. Methodology: Using the keywords “cracked tooth syndrome”, “etiology”, “prevalence”, “pulp Alejandro Mas-Enriquez involvement” and “treatment”, the MEDLINE/PubMed and ScienceDirect databases were searched, with Associate Professor, Universidad emphasis on the last 5 years. It was evaluated with the PRISMA and AMSTAR-2 guidelines. Autonoma de Nuevo Leon, Facultad de Odontologia, Monterrey, Nuevo Results: There are many causes for cracks, the main one being malocclusion. Another is due to Leon, CP 64460, Mexico restorations, pieces to which amalgam was placed due to the extension of the cavity for the retentions. The second lower molar presents more frequently fissures due to premature contact.
    [Show full text]
  • Orofacial Pain
    QUINTESSENCE INTERNATIONAL OROFACIAL PAIN Noboru Noma Cracked tooth syndrome mimicking trigeminal autonomic cephalalgia: A report of four cases Noboru Noma DDS, PhD1/Kohei Shimizu DDS, PhD2/Kosuke Watanabe DDS3/Andrew Young DDS, MSD4/ Yoshiki Imamura DDS, PhD5/Junad Khan BDS, MSD, MPH, PhD6 Background: This report describes four cases of cracked All cases mimicked trigeminal autonomic cephalalgias, a group tooth syndrome secondary to traumatic occlusion that mim- of primary headache disorders characterized by unilateral icked trigeminal autonomic cephalalgias. All patients were facial pain and ipsilateral cranial autonomic symptoms. referred by general practitioners to the Orofacial Pain Clinic at Trigeminal autonomic cephalalgias include cluster headache, Nihon University Dental School for assessment of atypical facial paroxysmal hemicrania, hemicrania continua, and short-lasting pain. Clinical Presentation: Case 1: A 51-year-old woman unilateral neuralgiform headache attacks with conjunctival presented with severe pain in the maxillary and mandibular injection and tearing/short-lasting neuralgiform headache left molars. Case 2: A 47-year-old woman presented with sharp, attacks with cranial autonomic features. Pulpal necrosis, when shooting pain in the maxillary left molars, which radiated to caused by cracked tooth syndrome, can manifest with pain the temple and periorbital region. Case 3: A 49-year-old man frequencies and durations that are unusual for pulpitis, as was presented with sharp, shooting, and stabbing pain in the max- seen in these cases. Conclusion: Although challenging, dif- illary left molars. Case 4: A 38-year-old man presented with ferentiation of cracked tooth syndrome from trigeminal intense facial pain in the left supraorbital and infraorbital areas, autonomic cephalalgias is a necessary skill for dentists.
    [Show full text]
  • Application of Lasers in Treatment of Oral Premalignant Lesions
    Symbiosis www.symbiosisonline.org www.symbiosisonlinepublishing.com Review article Journal of Dentistry, Oral Disorders & Therapy Open Access Application of Lasers in Treatment of Oral Premalignant Lesions Amaninder Singh*1, Akanksha Zutshi2, Preetkanwal Singh Ahluwalia3, Vikas Sharma4 and Vandana Razdan5 1,4oral and maxillofacial surgery, reader, National Dental College and Hospital, Dera Bassi, Punjab 2oral and maxillofacial surgery, senior lecturer, National Dental College and Hospital, Dera Bassi, Punjab 3oral and maxillofacial surgery, professor, National Dental College and Hospital, Dera Bassi, Punjab 5Pharmacology, professor, Govt. Medical College and Hospital, Jammu Received: April 03, 2018; Accepted: June 04, 2018; Published: June 11, 2018 *Corresponding author: Amaninder Singh, House No- 620, Phase- 6, mohali, 160055, E-mail address: [email protected] Abstract radiation. Laser systems and their application in dentistry and especially the basis of energy of the beam and wavelength of the emitted oral surgery are rapidly improving today. Lasers are being used as a niche tool as direct replacement for conventional approaches ClassificationGas lasers of lasers [6] CO advantages of lasers are incision of tissues, coagulation during Argon like scalpel, blades, electro surgery, dental hand piece. The specific Liquid Dyes2 canoperation be used and for treatmentpostoperative of conditions benefits likesuch lowas premalignant postoperative lesions, pain, better wound healing. For soft tissue oral surgical procedures lasers Solid
    [Show full text]
  • Reaction of Antigens Isolated from Herpes Simplex Virus Transformed Cells with Sera of Squamous Cell Carcinoma Patients1
    [CANCERRESEARCH36,4394-4401,December1976] Reaction of Antigens Isolated from Herpes Simplex Virus transformed Cells with Sera of Squamous Cell Carcinoma Patients1 Mary F. D. Notter and John J. Docherty2 Department of Microbiology and Cell Biology, The Pennsylvania State University, University Park, Pennsylvania 16802 SUMMARY we examined the reactive patterns of cancer patient sera with antigens isolated from cells transformed by these vi Antigens isolated from herpes simplex virus type 1, muses. Our studies reveal a positive correlation between herpes simplex virus type 2, on cytomegalovinus-trans sera of patients with diagnosed squamous cell carcinoma formed hamster cells were tested against 66 semafrom non and antigens isolated from both HSV-1- and HSV-2-trans cancer individuals or patients with different types of cancer. farmed cells. By use of the microcomplement fixation procedure to quan tify all antigen-antibody interactions, it was observed that MATERIALS AND METHODS 94% (p < 0.001) of all semafrom patients with squamous cell carcinoma reacted with antigens from herpes simplex virus Cells. Hamster cells transformed by HSV-1 [14-012-8-1; type 1-transformed cells, while 84% (p < 0.001) of the same (9)], HSV-2 [333-8-9 (8)], on cytomegalovirus [CX-90-3B, T2 sena reacted with antigen preparations from herpes simplex (2)] were acquired from F. Rapp, M. S. Hershey Medical virus type 2-transformed cells. When semafrom patients with Center, Hershey, Pa., while cell cultures of normal non adenocancinoma, sarcoma, liposarcoma, and melanoma transformed hamster cells were prepared from 13-day-old were tested against these antigens, there was no significant embryos (Lakeview Hamster Colony, Newfield, N.
    [Show full text]
  • Malignant Transformation of Actinic Cheilitis
    INQUIRY ACTINIC CHEILITIS Malignant transformation of actinic cheilitis BACKGROUND analysis of the results and suffered from a lack of tests of statistical fi Actinic cheilitis (AC) is a chronic inflammation of the lip, usually signi cance. It also included the 9 patients diagnosed with SCC at the lower lip, caused by excessive exposure to solar or artificial the beginning of the study with the 2 who had malignant transfor- ultraviolet (UV) radiation. The UV radiation directly and indi- mation over the course of the study and reported a rate of ma- rectly damages the DNA in skin epithelial cells, causing genetic lignant transformation of 16.9%, which was inaccurate. aberrations and immunosuppression. AC is therefore considered to have malignant transformation potential, although the risk of fi such transformation remains unde ned. Globally, the prevalence Clinical Significance of AC is between 0.45% and 2.4%, but tends to be significantly higher among populations who participate in outdoor activities, A lack of research concerning the malignant transfor- rising to as much as 43.2%. A large percentage of the lower lip mation from AC to SCC is evident in the findings of carcinomas reported shows links to pre-existing AC lesions, this review. In addition, flaws in the single study iden- which indicates the malignant transformation potential of this dis- tified make it an unreliable guide to the potential malig- order. A review of the literature was undertaken to determine nant transformation of AC. Many factors enter into the the malignant transformation rate of AC. transformation process and influence whether it will occur and what its speed of progression will be.
    [Show full text]
  • Actinic Cheilitis and Lip Squamous Cell Carcinoma
    J Clin Exp Dent. 2019;11(1):e62-9. Actinic cheilitis and lip squamous cell carcinoma Journal section: Oral Medicine and Pathology doi:10.4317/jced.55133 Publication Types: Review http://dx.doi.org/10.4317/jced.55133 Actinic cheilitis and lip squamous cell carcinoma: Literature review and new data from Brazil Fernanda-Weber Mello 1, Gilberto Melo 1, Filipe Modolo 2, Elena-Riet-Correa Rivero 2 1 Postgraduate Program in Dentistry, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil 2 Department of Pathology, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil Correspondence: Department of Pathology Health Sciences Center Federal University of Santa Catarina University Campus, Trindade Mello FW, Melo G, Modolo F, Rivero ERC. Actinic cheilitis and lip squa- Florianópolis, 88.040-370, SC, Brazil mous cell carcinoma: Literature review and new data from Brazil. J Clin Exp [email protected] Dent. 2019;11(1):e62-9. http://www.medicinaoral.com/odo/volumenes/v11i1/jcedv11i1p62.pdf Article Number: 55133 http://www.medicinaoral.com/odo/indice.htm Received: 10/07/2018 © Medicina Oral S. L. C.I.F. B 96689336 - eISSN: 1989-5488 Accepted: 10/12/2018 eMail: [email protected] Indexed in: Pubmed Pubmed Central® (PMC) Scopus DOI® System Abstract Background: To investigate the prevalence of malignant and potentially malignant lesions of the lip in an oral pa- thology service and to compare these data with a literature review. Material and Methods: A total of 3173 biopsy reports and histopathological records were analyzed. Cases with a histological diagnosis of actinic cheilitis (AC) with or without epithelial dysplasia, in situ carcinoma, or lip squa- mous cell carcinoma (LSCC) were included.
    [Show full text]
  • Supernumerary Teeth in Primary Dentition Associated to Palatal Polyps
    Revista Odontológica Mexicana Facultad de Odontología Vol. 17, No. 3 July-September 2013 pp 168-172 CASE REPORT Supernumerary teeth in primary dentition associated to palatal polyps. Case report Dientes supernumerarios en dentición primaria asociados a pólipos palatinos. Reporte de caso Thalia Sánchez Muñoz Ledo,* Alejandro Hinojosa Aguirre,§ Germán Portillo Guerrero,II Fernando Tenorio Rocha¶ ABSTRACT RESUMEN Polyps are rare in children. The present article reports the clinical Los pólipos son poco frecuentes en niños. En este artículo se pre- case of a 14 month old male patient brought for treatment to the senta un caso clínico de un niño de un año dos meses que acude Pedodontics Clinic of the Graduate School, National School of a la Clínica de Odontopediatría de la DEPeI UNAM con dos póli- Dentistry National University of Mexico. He presented two palatal pos fibroepiteliales palatinos ubicados a ambos lados de la papila fibro-epithelial polyps, located at both sides of the incisive papilla. incisiva, 10 días posteriores a la excisión quirúrgica se observó la 10 days after surgical excision, a supernumerary tooth erupted in erupción de un diente supernumerario en el paladar, y 25 días des- the palate. 25 days later, eruption of a second supernumerary tooth pués se observó la erupción de un segundo diente supernumerario. was observed. Both teeth were extracted. Histological diagnosis Ambos dientes fueron extraídos. El diagnóstico histológico de las of palatal lesions was giant fibroblast fibroma. Nevertheless, no lesiones en el paladar fue: fibroma de fibroblastos gigantes; sin -em histological evidence was found to show possible relationship bargo, no se encontró evidencia histológica que mostrara alguna between presence of palatal polyps and supernumerary teeth.
    [Show full text]
  • The Peripheral Giant Cell Granuloma in Edentulous Patients: Report of Three Unique Cases
    Published online: 2019-09-30 The Peripheral Giant Cell Granuloma in Edentulous Patients: Report of Three Unique Cases Osman A. Etoza Ahmet Emin Demirbasa Mehmet Bulbulb Ebru Akayc ABSTRACT The peripheral giant cell granuloma (PGCG) is a rare reactive exophytic lesion taking place on the gingiva and alveolar ridge usually as a result of local irritating factors such as trauma, tooth extrac- tion, badly finished fillings, unstable dental prosthesis, plaque, calculus, chronic infections, and im- pacted food. This article presents 3 cases of PGCG that presented at the same location of the edentu- lous mandible of patients that using complete denture for over ten years. (Eur J Dent 2010;4:329-333) Key words: Peripheral giant cell granuloma; Chronic irritation; Edentulous patients; Complete denture. INTRODUCTION Giant cell granuloma lesions (peripheral and teoclastoma, or giant-cell hyperplasia. Etiologic central) are benign, non-odontogenic, moderately factors are not known, although it is thought that rare tumors of the oral cavity. They develop pe- it may be due to an irritant or aggressive factor ripherally (within gingiva) or centrally (in bone).1 such as trauma, tooth extraction, badly finished The peripheral giant cell granuloma (PGCG) is a fillings, unstable dental prosthesis, plaque, calcu- rare reactive exophytic lesion taking place on the lus, chronic infections, or impacted food.2,3 Clini- gingiva and alveolar ridge, also known as a giant- cal appearance of PGCGs can present as polyploi- cell epulis, giant-cell reparative granuloma, os- dy or nodular lesions, primarily bluish red with a smooth shiny or mamillated surface, stalky or 2,4,5 a Erciyes University, Faculty of Dentistry, Department of sessile base, small and well demarcated.
    [Show full text]
  • Pigmented Villonodular Synovitis of the Temporomandibular Joint: a Case Report and the Literature Review
    1314 Cai et al. Case Report TMJ Disorders J. Cai1, Z. Cai1, Y. Gao2 1Department of Oral and Maxillofacial Pigmented villonodular synovitis 2 Surgery, Beijing, China; Department of Oral Pathology, Peking University School & of the temporomandibular joint: Hospital of Stomatology, Beijing, China a case report and the literature review J. Cai, Z. Cai, Y. Gao: Pigmented villonodular synovitis of the temporomandibular joint: a case report and the literature review. Int. J. Oral Maxillofac. Surg. 2011; 40: 1314–1322. # 2011 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved. Abstract. Pigmented villonodular synovitis (PVNS) is an uncommon benign proliferative disorder of synovium that may involve joints, tendon sheaths, and bursae. It most often affects the knees, and less frequently involves other joints. It presents in the temporomandibular joints (TMJs) extremely rarely. The authors report an elderly female patient with PVNS of the TMJ with skull base extension, who had traumatic history in the same site. It was diagnosed through core-needle Keywords: pigmented villonodular synovitis (PVNS); synovitis; temporomandibular joint biopsy, which was not documented in the literature. Radical excision and follow-up (TMJ). for 7–8 years was recommended because of the reported malignant transformation and high recurrence rate. This case and previously reported cases in the literature are Accepted for publication 2 March 2011 reviewed and discussed. Available online 6 April 2011 The term pigmented villonodular synovi- were reported in detail (Table 1). The visits and mouth-opening for a long time tis (PVNS) was introduced by JAFFE et al. authors present an additional case of during the operation.
    [Show full text]
  • Evaluation of Effect of a Vitamin-Based Barrier Cream on the Clinical Severity of Actinic Cheilitis
    J Clin Exp Dent. 2020;12(10):e944-50. Evaluation of effect of a vitamin-based barrier cream on the clinical severity of actinic cheilitis Journal section: Oral Medicine and Pathology doi:10.4317/jced.57013 Publication Types: Research https://doi.org/10.4317/jced.57013 Evaluation of effect of a vitamin-based barrier cream on the clinical severity of actinic cheilitis: A preliminary study Mariana-Sudati Rodrigues 1, Eduardo-Oliveira Kaefer 2, Juliana-Tomaz Sganzerla 1, Humberto-Thomazi Gassen 1, Rubem-Beraldo dos Santos 1, Sergio-Augusto-Quevedo Miguens-Jr 1 1 Lutheran University of Brazil – ULBRA (Graduate Program in Dentistry), Canoas, RS, Brazil 2 Lutheran University of Brazil – ULBRA (School of Dentistry), Cachoeira do Sul, RS, Brazil Correspondence: Department of Oral Medicine, Graduate Program in Dentistry Lutheran University of Brazil Av. Farroupilha 8001, Prédio 59 Bairro São José, Canoas – RS - CEP 92425-900 [email protected] Rodrigues MS, Kaefer EO, Sganzerla JT, Gassen HT, dos Santos RB, Received: 07/03/2020 Accepted: 02/07/2020 Miguens-Jr SAQ. Evaluation of effect of a vitamin-based barrier cream on the clinical severity of actinic cheilitis: A preliminary study. J Clin Exp Dent. 2020;12(10):e944-50. Article Number: 57013 http://www.medicinaoral.com/odo/indice.htm © Medicina Oral S. L. C.I.F. B 96689336 - eISSN: 1989-5488 eMail: [email protected] Indexed in: Pubmed Pubmed Central® (PMC) Scopus DOI® System Abstract Background: Actinic Cheilitis (AC) is a pathological condition of the labial mucosa considered potentially malig- nant. The aim of this study was to investigate the effect of treatment of AC with daily use of a vitamin-based barrier cream.
    [Show full text]
  • Multiple Large Peripheral Giant Cell Granuloma: a Case Report
    CASE REPORT BALIKESİR SAĞLIK BİLİMLERİ DERGİSİ / BALIKESIR HEALTH SCIENCES JOURNAL MULTIPLE LARGE PERIPHERAL GIANT CELL GRANULOMA: A CASE REPORT BÜYÜK BOYUTLARDA MULTİPL PERİFERAL DEV HÜCRELI GRANÜLOM: VAKA RAPORU Mustafa Gümüşok1 Murat Özle2 Begüm Okur2 Anıl Seçkin2 Farid Museyibov3 Özlem Üçok1 Sedat Çetiner2 1Gazi Üniversitesi Diş Hekimliği Fakültesi, ÖZET Ağız, Diş Ve Çene Radyolojisi Anabilim Dalı, Ankara Periferal dev hücreli granülom (PDHG) oral bölgenin sık izlenen dev hücreli bir lezyonudur. 2Gazi Üniversitesi Diş Hekimliği Fakültesi, PDHG’ler gerçek bir neoplazmı temsil etmezler. Etyolojileri çok açık olmayan bu lezyonların, Ağız, Diş Ve Çene Cerrahisi Anabilim Dalı, travma veya lokal irritasyonlara bağlı gelişen reaktif bir lezyon olduğu düşünülmektedir. Ankara PDHG’lere kadınlarda erkeklere oranla daha sık, mandibulada ise maksilladan daha fazla 3 Gazi Üniversitesi Diş Hekimliği Fakültesi, rastlanılır. Gingiva veya dişsiz alveolar kret üzerinde kırmızı, kırmızı-mavi nodüler kitle şeklinde Oral Patoloji Anabilim Dalı, Ankara görülürler. Bu olgu raporunda, 48 yaşında erkek hastada görülen, maksilla sol santral kesici - sağ kanin kesici dişler ve mandibula sağ santral kesici-sol kanin kesici dişler bölgesinde lokalize, Yazışma Adresi: yüzde asimetriye neden olan büyük boyutlu PDHG’ler sunulmuştur. Multipl PDHG vakasının Mustafa Gümüşok radyolojik, klinik, histopatolojik bulguları ile birlikte teşhis, tedavi ve 6 aylık takibi rapor Gazi Üniversitesi Diş Hekimliği Fakültesi Ağız edilmiştir. Diş Ve Çene Radyolojisi Asti Karşısı Emek Ankara Ankara – Türkiye Anahtar Kelimeler: Periferal dev hücreli granülom, mandibula, maksilla, multipl lezyon SUMMARY E posta: [email protected] Peripheral giant cell granuloma (PGCG) is the most common oral giant cell lesion. PGCG Kabul Tarihi: 25 Şubat 2015 presumably does not represent a true neoplasm. PGCG is believed to be stimulated by local irritation or trauma besides the causing of PGCG isn’t known exactly.
    [Show full text]