(12) United States Patent (10) Patent No.: US 8,557,285 B2 Plachetka (45) Date of Patent: *Oct
US008557285B2 (12) United States Patent (10) Patent No.: US 8,557,285 B2 Plachetka (45) Date of Patent: *Oct. 15, 2013 (54) PHARMACEUTICAL COMPOSITIONS FOR (56) References Cited THE COORONATED DELVERY OF NSAIDS U.S. PATENT DOCUMENTS (75) Inventor: John R. Plachetka, Chapel Hill, NC 4,198.390 A 4, 1980 Rider ............................ 424/471 (US) 4.255.431 A 3/1981 Junggren et al. .............. 514,338 (73) Assignee: Pozen Inc., Chapel Hill, NC (US) (Continued) (*) Notice: Subject to any disclaimer, the term of this FOREIGN PATENT DOCUMENTS patent is extended or adjusted under 35 AU 2006235929 11, 2006 U.S.C. 154(b) by 0 days. CA 2139653 T 2001 This patent is Subject to a terminal dis (Continued) claimer. OTHER PUBLICATIONS (21) Appl. No.: 13/215,855 Goldstein et al., “PN400 significantly improves upper (22) Filed: Aug. 23, 2011 gastrointestinal tolerability compared with enteric-coated naproxen alone in patients requiring chronic NSAID therapy: Results from (65) Prior Publication Data Two Prospective, Randomized, Controlled Trials.” POZEN Inc. sponsored study, 2009. (Document D15 from Letter to European US 2012/OO64156A1 Mar. 15, 2012 Patent Office for counterpart European Application No. 02734602.2, Related U.S. Application Data regarding Oral Proceedings dated Dec. 18, 2009). (60) Division of application No. 12/553,804, filed on Sep. (Continued) 3, 2009, now abandoned, which is a division of application No. 11/129,320, filed on May 16, 2005, Primary Examiner — Nissa Westerberg now Pat. No. 8,206,741, which is a (74) Attorney, Agent, or Firm — Parker Highlander PLLC continuation-in-part of application No.
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